The food supply offers a rich panoply of (bio)chemical compounds that affect biological function.
While the latest data suggest that there are over 135,000 compounds in the food supply, knowledge
of their relationship to (patho)biological phenotype is rather limited, with a mere ~200 having been
studied epidemiologically and/or functionally. This ‘dark matter’ of nutrition offers a stunning
opportunity to explore the normal biochemical functions of food compounds, as well as their
potential role as drugs. Using a combination of machine learning, artificial intelligence, network
medicine, epidemiological association, and cell-based experimentation, we demonstrate an effective
approach to dissecting the functional richness of (bio)chemicals in the food supply, and their
potential application to health and disease.
24 ottobre 2022, alle ore 10.00, Aula A del
Dipartimento di Chimica e tecnologie del farmaco (Edificio CU019)