Delivered study plan 2023/2024

I year
First year students have taken courses organized by the Scientific Board as well as take part to workshops and schools in agreement with the supervisor.
1° Year (39° cycle)
 
1 CFU (8 hours) Strategies in drug discovery and drug analysis    
Teacher Dr Sara Consalvi
Course Dates Time Where
Strategies in drug discovery_Part 1 02/02/2024 15.30 – 17.30 lesson online
Strategies in drug discovery_Part 2 09/02/2024 15.30 – 17.30 lesson online
Strategies in drug discovery_Part 3 16/02/2024 15.30 – 17.30 lesson online
Strategies in drug discovery_Part 4 23/02/2024 15.30 – 17.30 lesson online
1 CFU (8 hours) Metabolomic analysis in food
sciences		    
Teacher Dr Cinzia Ingallina    
Course Dates Time Where
Primary and secondary metabolism 01/03/2024 15.00 – 17.00 lesson online
Metabolomic analysis in food science 08/03/2024 15.00 – 17.00 lesson online
Metabolomic approach in natural
product research		 15/03/2024 15.00 – 17.00 lesson online
Common synthetic scaffolds in the synthesis of structurally diverse
natural		 22/03/2024 15.00 – 17.00 lesson online
1 CFU (8 hours) Green Organic Chemistry    
Teacher Dr Mattia Bizzarri
Course Dates Time Where
Introduction to green chemistry 26/04/2024 09.00 – 11.00 lesson online
Use of catalytic reagents in organic
synthesis_Part 1		 03/05/2024 09.00 – 11.00 lesson online
Use of catalytic reagents in organic
synthesis_Part 2		 10/05/2024 09.00 – 11.00 lesson online
Role of green chemistry in the
synthesis of bioactive compounds		 17/05/2024 09.00 – 11.00 lesson online
1 CFU (8 hours) Biochemistry of bioactive peptides
Teacher Dr Bruno Casciaro
Course Dates Time Where

 
Introduction to bioactive peptides 15/05/2024 15.00 – 17.00 AULA B
Antimicrobial peptides 17/05/2024 15.00 – 17.00 AULA B
Nanotechnologies to ameliorate the biological profile of antimicrobial
peptides		 22/05/2024 15.00 – 17.00 AULA B
Methodologies for the characterization of bioactive
peptides		 24/05/2024 15.00 – 17.00 AULA B

Method of choosing the subject of the thesis
Each student, at the beginning of the first year and in accordance with the Scientific Board, had selected a supervisor. 
Each student has agreed on a possible  project thesis with the supervisor.

Admission to the second year
At the end of the first year students prepared a report that demonstrated their understanding of the field of study and that they have made a reasonable start to the specific project.
After the report has been independently assessed by the feedback supervisor and the Director of Graduate Studies, an interview has been taken to discuss progress.
On the basis of all the evidence of achievement to date the Scientific Board decided whether a student can continue into the second year with a PhD registration. 
 
II year
Second year students have taken courses organized by the Scientific Board as well as take part to workshops and schools in agreement with the supervisor.
2° Year (38° cycle)
 
1 CFU (8 hours) Natural organic compounds of food and pharmaceutical interest    
Teacher Dr Marco Franceschin    
Course Dates Time Where
Techniques for the study and characterization of secondary metabolites; main biogenetic pathways
Acetate and mevalonate pathway: terpenes and cannabinoids		 04/12/2023 9.00 – 11.00 Lesson online
Shikimic acid pathway: flavonoids Examples of secondary metabolites
with known biological activity		 11/12/2023 9.00 – 11.00 Lesson online
Alkaloids: examples of natural antitumoral compounds
Natural antioxidants (polyphenols, vitamin E and vitamin C)
Nutrition facts label: food and drug additives (preservatives and colorants)		 18/12/2023 9.00 – 11.00 Lesson online
Module 3 “quality” of the dossier: structure and information; basis of
GMP (Good Manufacturing Practice)		 15/01/2014 9.00 – 11.00 Lesson online
1 CFU (8 hours) Multidimensional mass spectrometry for applications in the (bio) chemical, pharmaceutical and food fields    
Teacher Dr Davide Corinti    
Course Dates Time Where
Introduction to Mass Spectrometry
for life sciences applications		 16/01/2024 16.00 – 18.00 Blended/Aula B

 
Selectivity and applications of mass
spectrometry ionization sources		 18/01/2024 16.00 – 18.00 Blended/ Aula B
Ion activation methods for structural recognition of ions of biological
interest		 23/01/2024 16.00 – 18.00 Blended/ Aula B
Applications of mass spectrometry to
metabolomics		 25/01/2024 16.00 – 18.00 Blended/ Aula B
       
1 CFU (8 hours) Development of NMR protocols for food analysis    
Teacher Dr Mattia Spano    
Course Dates Time Where
Novel foods: definition 06/02/2024 16.00 – 18.00 lesson online
The case study of Canapa 13/02/2024 16.00 – 18.00 lesson online
The case study of Insect 20/02/2024 16.00 – 18.00 lesson online
Advanced methodologies to study
novel foods		 27/02/2024 16.00 – 18.00 lesson online
1 CFU (8 hours) Advanced methodologies for studying complex matrices    
Teacher Prof Andrea Calcaterra    
Course Dates Time Where
Introduction to natural products, extraction, isolation, and structure elucidation. Classifications in synthetic methodology, retrosynthetic analysis, synthons and
reagents, group disconnections		 05/03/2024 14.30 – 16.30 Blended/ Aula B
Regio- and chemoselectivity. Asimmetric synthesis, chiral auxiliary, racemic resolution. Useful reactions
in total synthesis		 12/03/2024 14.30 – 16.30 Blended/ Aula B
Useful reactions in total synthesis.
Control of stereochemistry. Catalytic asymmetric reactions		 19/03/2024 14.30 – 16.30 Blended/ Aula B

 
Total synthesis of thyroxine,
longifolene, reserpine, strychnine		 26/03/2024 14.30 – 16.30 Blended/ Aula B
1 CFU (8 hours) Cycle of advanced lessons    
Teacher Prof Stefano Stranges    
Course Dates Time Where
Chiral photon/chiral molecule interaction as a spectroscopic tool
for chiral recognition		 16/01/2024 15.00 – 16.00 lesson online
Teacher Prof Maria Elisa Crestoni    
Course Dates Time Where
Exploring the intrinsic properties of bioinorganic complexes by ion-
molecule reactions		 16/01/2024 16.00 – 17.00 lesson online
Teacher Prof Alessia Ciogli    
Course Dates Time Where
A dynamic approach to investigate
the stereochemical (in)stability of chiral compounds		 17/01/2024 15:00 – 17:00 Aula B
Teacher Prof. Luisa Mannina    
Course Dates Time Where
NMR methodologies in the study of
complex matrices		 13/02/2024 15.00 – 16.00 lesson online
Teacher Prof Barbara Chiavarino    
Course Dates Time Where
Advanced ion spectroscopy techniques: identification and structural characterization of
bioactive molecules		 16/04/2024 15.00 – 17.00 lesson online
Teacher Prof. Giancarlo Fabrizi    
Course Dates Time Where
Click chemistry, a powerful molecular assembly tool for the
widest range of applications		 05/06/2024 10.00 – 11.00 lesson in presence/ Aula B
Method of preparation of the thesis
At the beginning of the second year students were asked to produce a short research plan at the start of the year. 
The report has been independently assessed by the feedback supervisor and the Scientific Board.

Admission to the third year
At the end of the second year students prepared a report that demonstrated their understanding of the field of study and that they have made a reasonable start to the specific project.
After the report has been independently assessed by the feedback supervisor and the Director of Graduate Studies, an interview was taken to discuss progress.
On the basis of all the evidence of achievement to date the Scientific Board decided whether a student can continue into the second year with a PhD registration. 
 

 
III year
Third year students have taken courses organized by the Scientific Board as well as take part to workshops and schools in agreement with the supervisor.
3° Year (37° cycle)
 
1 CFU (8 hours) Advanced techniques in separation science for unravelling the complexity of natural products and (bio)pharmaceuticals: from small chiral molecules to peptides    
Teacher Dr Giulia Mazzoccanti
Course Dates Time Where
Introduction to Advanced Separation
Science		 16/01/2024 10.00 – 12:00 lesson online
Chiral separations 23/01/2024 10.00 – 12:00 lesson online
Peptides and protein: focus on
biopharmaceuticals		 30/01/2024 10.00 – 12:00 lesson online
Multidimensional liquid
chromatographic techniques		 06/02/2024 10.00 – 12:00 lesson online
1 CFU (8 hours) Biochemical aspects of nutrition    
Teacher Prof Anna Maria Giusti    
Course Dates Time Where
Total Food Quality: markers of
food processing		 18/04/2024 15.00 – 17.00 lesson online
Total food Quality: effects of thermal treatment on phytochemical
contents in plant foods		 16/05/2024 15.00 – 17.00 lesson online
Photoacustic techniques applied to non desctructive analysis of
phytochemicals in plant foods, Part I		 29/05/2024 15.00 – 17.00 lesson online
Photoacustic techniques applied to non desctructive analysis of
phytochemicals in plant foods, Part II		 12/06/2024 15:00- 17:00 lesson online
1 CFU (8 hours) Cycle of advanced lessons
Teacher Dr Luana Izzo    
Course Dates Time Where

 
Bioaccessibility of food waste bioactive compounds under in vitro
gastrointestinal digestion		 16/02/2024 14.30 – 16.30 lesson online
Case study - Dairy by-products 23/02/2024 14.30 – 16.30 lesson online
Teacher Dr Valeria Antonietta Pietropaolo
Course Dates Time Where
Natural antivirals to fight viral
diseases		 27/02/2024 15.00 – 16.00 lesson online
Teacher Prof Antonella Goggiamani
Course Dates Time Where
Recent advances in metal-assisted
cross-coupling processes		 5/07/2024 15.30 – 16.30 lesson online
Teacher Prof Dante Rotili    
Course Dates Time Where
Radiotracers for tumor radioguided
surgery		 16/07/2024 11.00 – 12.00 Aula C CU018 (Plesso Didattico
Tecce)
Teacher Prof Patrizia Paolicelli    
Course Dates Time Where
Micro and nanoencapsulation of biologically active molecules: new
trends and challenges		 26/07/2024 12.00 – 13.00 lesson online
  Cycle of lesson Closure    
Teacher Prof Caterina Scuderi
Course Dates Time Where
Journal club 18/03/2024 15.00 – 17.00 lesson online
Teacher Prof Chiara Di Meo
Course Dates Time Where
Journal club 07/05/2024 15.00 – 16.00 lesson online
Teacher Prof Giuseppe La Regina
Course Dates Time Where
How to write the PhD thesis 27/06/2024 15.00 – 16.00 lesson online
Teacher Prof Giovanna Poce
Course Dates Time Where
Journal club 19/07/2024 15.00 – 16.00 lesson online
Method of admission to the final examination
Before the end of September, each student produced a final progress review.
After the report has been independently assessed by the feedback supervisor and the Director of Graduate Studies, an interview was held.
On the basis of all the evidence of achievement to date the Scientific Board decided whether a student can discuss the final exam.


Final examination
The final defence took place in the form of a presentation to a scientific commitee composed of 3 experts.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma