Tutti i seminari attinenti alle tematiche di Biologia cellulare e dello Sviluppo organizzati da questo corso di dottorato, dal dottorato GBM, dai Dipartimenti di Sapienza, dalla scuola BEMM e da altre Istituzioni sono considerati validi per la formazione dei dottorandi, e sono elencati nel Report Annuale di ciascun dottorando.


Seminari degli Istituti del Polo San Lorenzo,
organizzati dal Dottorato BCS in collaborazione con IBPM/CNR BBCD/Sapienza e corsi di dottorato GBM (tenuti ogni due settimane circa in Aula Tatò - Via dei Sardi 70, 2° piano).

30-01-2023 Marco Paggi Unit of Cellular Networks and Molecular Therapeutic Targets IRCCS - Regina Elena National Cancer Institute, Rome “Repurposing the antipsychotic drug chlorpromazine in the treatment of glioblastoma: a fast track from lab results to clinical trials”Introduzione (inglese):

130-2-2023 Livia Perfetto Dipartimento di Biologia e Biotecnologie “C. Darwin” Sapienza Università di Roma “Network-based approaches to support Systems Medicine”
63-03-2023 ore 12.30 Massimiliano Lucidi, Department of Sciences, Università degli Studi Roma Tre “Super-resolution imaging and optical nanoscopy on bacteria”
20-03-2023 Maurizio Fanciulli, Department of Research, Diagnosis and Innovative Technologies, Traslational Research Area, IRCCS Regina Elena National Cancer Institute, Roma, “Enhancer engagement sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic Leukemia”
03-04-2023 Francesca Sardina, Istituto di Biologia e Patologia Molecolari, CNR, Roma “Microtubule network and spastin functions: new therapeutic perspectives for Hereditary Spastic Paraplegia”
17-04-2023 Enea Di Domenico, Dipartimento di Biologia e Biotecnologie ''C. Darwin'' Sapienza Università di Roma “Advances in exploring and manipulating the human skin microbiome”
08-05-2023 Emanuele Mauri, Dipartimento di Chimica, Materiali e Ingegneria Chimica "G. Natta",Politecnico di Milano "Hydrogel-based systems for biomedical applications: a leap into promising therapeutic strategies"
22-05-2023 Raymond Kaempfer, Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University, Jerusalem, Israel "HIV co-opts the host antiviral response to enable splicing of its own mRNA"
29-05-2023 Francesco Boccellato, Ludwig Institute for Cancer Research, University of Oxford, UK “Stem-cell driven models to understand epithelial response to infections and cancer initiation”
05-06-2023 Silvia Di Angelantonio, Dipartimento di Fisiologia e Farmacologia, Sapienza Università di Roma; Center for Life Nano- & Neuro-Science, IIT@Sapienza, Roma; Caterina Sanchini, Center for Life Nano- & Neuro-Science, IIT@Sapienza, Roma “Microtubule rearrangement as microglia reactivity marker”
19-06-2023 Paul Clarke, Frazer Institute, The University of Queensland, Australia “Mitotic cell death: a mechanism to prevent and treat cancer”
12-09-2023 Toshihide Okajima, ISIR, Osaka University, Japan “Neutron crystallography of bacterial copper amine oxidase: Real positions of hydrogen atoms in enzyme”
25-09-2023 Antonio Lazcano, Facultad de Ciencias, UNAM, El Colegio Nacional, Mexico “Prebiotic chemistry and the origin of life: back to the Miller experiment?”
9-10-2023 Jomon Joseph, National Centre for Cell Science, Pune, India “Cell biology of Annulate Lamellae – an unexplored organelle"

Seminari organizzati dal corso di dottorato in Biologia Cellulare e dello Sviluppo e tenuti da docenti stranieri

01-03-2023 Martin Stegmann TUM School of Life Sciences, Technische Universität, München, Germany "Coordination of plant growth and stress by endogenous peptides"
03-05-2023 Luisa Currado - Cantaluppi & Partners-Rappresentante professionale presso l’UAMI (Ufficio Marchi e Design comunitario) e l’EUIPO (Ufficio dell’Unione Europea per la Proprietà Intellettuale) “IP for dummies: patent procedure pills”
30-03-2023 Claudio Moser, Fondazione Edmund Mach, San Michele all'Adige, Trento “Grapevine breeding via gene editing”
21-04-2023 Monica De Caroli, Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali, Università del Salento, Lecce "And there was light: a green lantern in the plant cell wall”
13-06-2023 Sara Raggi, Umeå Plant Science Centre, Umeå, Sweden “Investigating the molecular and cellular mechanisms regulating apical hook development in A. thaliana”
13-06-2023 Federica Locci, Max Planck Institute, Cologne, Germany “Sensing the danger: a confluent view of plant innate immunity”
13-06-2023 Nora Gigli Bisceglia, Utrecht University, Utrecht, The Netherlands "Exploring the role of cell wall modification and sensing in activating stress responses in plants"


I seminari degli anni precedenti sono riportati nel link a destra della pagina


A journey from distress signals in plants to biotechnology for health and energy production (‘Stress is natural’)
Plant development and stress responses are regulated by complex signalling networks that mediate specific and dynamic plant responses upon activation by various types of signals. Jasmonates (JAs) mediate responses to stress and act like growth inhibitors. The latest work has identified new regulatory nodes regulating diverse plant responses to developmental and environmental cues. In my laboratory, we are interested in discovering the cellular components linking plant stress responses to growth processes with the aim to improve yield and adaptation of plants to their environment. We also exploit the ability of JAs to induce protective specialized metabolites to develop novel functional screenings to improve the understanding of key pathways leading to the production of economically important compounds. A second research line is aimed at tailoring the composition of cell wall polymers to improve processing of biomass and the improvement of key traits to produce biomass and biofuels in microbes and plants is achieved by affecting the composition of plant cell wall polymers. A review of the state of the art and the latest results will be presented.
Routes and mechanisms of membrane protein trafficking, endocytosis and turnover under the challenge of polarity
In this 2nd EMBO Lecture, Prof. Daillinas will highlight how previous and ongoing studies on membrane trafficking of UapA and other transporters unravel novel routes and mechanisms of endocytosis and translocation to the plasma membrane via Golgi-bypass. These findings present paradigmatic shifts in our knowledge on membrane cargo trafficking in eukaryotes.
Structure-Function relationships in transporters: lessons from model fungal systems
The lecture will present a collection of genetic, functional and biophysical findings concerning structure-function relationships in the UapA purine transporter, a paradigmatic case of elevator-type transporters, present in all organisms. These findings shed light on how specific substrate recognition and transport is determined and provide hints on how the molecular knowledge obtained can be used to genetically modify transporters. Specific examples of fungal transporters in which cytosolic tails have acquired, through evolution, novel functions related to control of transporter biogenesis and turnover, but also how cytosolic tails affect transport catalysis from a distance, will be presented.
One-step nanoscale expansion microscopy reveals protein shapes using conventional microscopes

Therapeutic targeting of mitochondrial dynamics vulnerabilities in multiple myeloma

The cytoskeleton regulatory protein hMENA affects the tumor immune microenvironment of lung cancer

Functional Genomics of Microsatellite Unstable Tumors and Therapeutic Target Discovery

Spastin recovery: opening up new therapeutic perspectives for hereditary spastic paraplegia

New functional connections of the plant ER

Prediction of protein-RNA interactions from single-cell transcriptomic data

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