The PhD course in Cell and Developmental Biology is an Interdisciplinary and Innovative Ph.D. Course and aims to provide students with a high profile and highly interdisciplinary approach, because based on widely diversified conceptual and methodological approaches:

In vitro cultures
Genetics of bacteria, yeast, Drosophila, mouse and plants
Chemical genetics
Heterologous expression in bacteria and eukariots
Cell / organ genetic transformation
Biochemistry and Molecular biology
"Omic" studies (transcriptomics, proteomics, metabolomics, interactomics etc.)
Cell fractionation
Microscopy Immunocytochemistry and electron microscopy
Live Cell Imaging
Structural biology

Main themes addressed by this Ph.D. Course:
Cell membrane: organization and function
Receptors: growth factor receptors / immune receptors / GPCR / intracellular / nuclear receptors in animals and plants Signal transduction
Regulation of and from the cytoskeleton
Nuclear and organelle dynamics
Molecular motors and other cellular machines Intracellular traffic / transport
Post-translational modifications and their regulation
Nuclear matrix, chromatin and genome
Control mediated by RNA / non-coding sequences and their functions
Cellular processes in development and disease
Study of cells in 3 and 4 dimensions
Determinants of cell fate
Stem cell biology
Biology of subcellular organelles
Biology of single-celled organisms
Microbes (including viruses) and interaction between host cells Immunity and microenvironment
Models of human diseases
Metabolic pathways: subcellular, cellular and subcellular compartmentalization and regulatory mechanisms
Metabolic control
Damage and DNA repair
Translational cellular science

The main goal of our PhD program is to give to our students a basic knowledge in the topics of Cell Biology as well as a broad experimental training with the aim to make them able to compete for international or national calls as qualified postdoctoral researchers.

We strongly encourage PhD projects which exploit integrated and interdisciplinary approaches to key aspects of Cell Biology. We also encourage the students to take full responsability of their work and to improve their communication skills. This is done by:
  1. requiring yearly presentations of their results in the form of public seminars (in English);
  2. appointing external tutors for in depth analysis of their scientific results;
  3. encouraging their attendance to international and national meetings and stages (they have individual budgets dedicated to these activities).

The updating of their scientific background is pursued by encouraging their participation to conferences performed by well known italian and foreigner scientists that we invite each year. These seminars, monographic or coordinated in series, are often co-organised with the BEMM (Biologia e Medicina Molecolare) PhD school or with other PhD programs.


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