HUMAN BIOLOGY AND MEDICAL GENETICS

Call for application 41th cycle

Bando ordinario

Educational goals and objectives

The PhD in Human Biology and Medical Genetics aims to provide a high-profile preparation in integrated and highly advanced topics of cellular, molecular biology and medical genetics. PhD students receive in-depth experimental training, including both basic research and its applicative aspects in various fields of cellular physiology and pathology and medical genetics, also with reference to the diagnostic definition of complex clinical cases.
The primary objective is to train young researchers by inserting them in innovative research projects of high scientific depth, encouraging them towards a rigorous, independent, critical and creative attitude.
A strong point of the training of doctoral students is the integration of wet-lab and computational biology experiences, for the training of researchers capable of consciously managing both the design/implementation of complex experiments and the subsequent analyzes with computational tools, in the field of research and diagnostics in medical genetics. Together, students can deepen their theoretical knowledge through an adequate consultation of the scientific literature and critically discussing the results of their research activity in weekly seminars and annual presentations, frequently held in English. In addition, multiple interdisciplinary seminars and theoretical and practical courses are offered to students within the BeMM (Biology and Molecular Medicine) PhD school. Students are also encouraged to participate in national and international congresses or courses, having an individual budget made available by the PhD program. The primary objective is also to provide the skills to finalize one's work to the production of scientific publications in highly prestigious journals.
Another objective of this PhD course is the internationalization promoted by encouraging people to attend laboratories abroad for continuous periods. Furthermore, during the course, foreign teachers are invited to carry out lectures, seminars and courses.

The PhD in Human Biology and Medical Genetics is divided into two curricula:
1) Human Biology: addresses the study of different themes of molecular and cellular biology, with an approach aimed at understanding the fundamental mechanisms of cell functioning, differentiation, proliferation and transformation and their application in various fields of human physiology and pathology.
2) Medical Genetics: addresses the study of the molecular defects underlying genetic diseases through the application of Next Generation Sequencing and cytogenomics sequencing technologies, and functional studies. Particular interest is aimed at the transfer of this knowledge in genetic counseling for a correct clinical setting, for prognosis and follow-up, and for any prevention and therapeutic programs.

Specifiche economiche

Sapienza Scholarships	Other Scolarships	Departments	Without scholarship
3	1	0	1

Themes, curriculum and specific competence

Borse ENTI TERZI, PARTENARIATI ESTESI, ECCELLENZA

Tematica: Studio del ruolo della sovraespressione di WRNIP1 nei meccanismi molecolari della chemioresistenza nei tumori, in particolare quelli con fenotipo "BRCAness
Ente finanziatore: ISTITUTO SUPERIORE DI SANITÀ (ISS)
Competenze richieste: nessuna competenza specifica richiesta

Admission Procedure

Qualifications assessment	The following will be evaluated: (1) academic background, considering: master's degree, specialized degree, or single-cycle degree, ongoing degree (limited to master's degree or single-cycle degree); (2) publications; (3) scientific background, taking into account: national and international research experiences (including Erasmus), training courses, and research scholarships.

Oral interview	The oral examination will consist of two parts: (1) Presentation of a research project: the candidate is required to present a project that is consistent with the research areas of the PhD program in Human Biology and Medical Genetics. The evaluation will be based on knowledge of the state of the art, originality and innovative content, clarity, and completeness of the presentation of objectives, methodologies, and potential results, feasibility of the project, relevance of the project to the educational objectives of the PhD program. It is emphasized that a written project should NOT be submitted, and the presentation does not involve the use of a computer; (2) Skills assessment: the candidate will be asked questions related to basic knowledge of cellular/molecular biology and general/medical genetics, acquired technical skills, and the ability to master them. At the end of the oral examination, an English language proficiency test will be conducted, which will involve reading and translating a paragraph from an article in English on a topic related to the themes of the PhD program. The minimum positive score for the oral test is 50/80.
language	ITALIANO

contacts and info

oriana.dangelogargano@uniroma1.it laura.stronati@uniroma1.it

Curriculum studiorum

Graduation date and grade of the Master's degree
detailed list of exams including completion dates and scores of Masters's degree
History of Scholarships, Research Grants (or similar)
Certificates of Foreign Languages
Certificates of participation in post-graduate university courses
certificates of Participation in research groups
certificates of Participation in internships
Other University Awards/Degrees (e.g.: awards in competition, second degree)

Required documentation

§ List of publications

optional, the file must be uploaded within le ore 23:59 del 19/06/2025

§ Curriculum Vitae et Studiorum

mandatory, the file must be uploaded within le ore 23:59 del 19/06/2025

Language Skills

the candidate must know the following languages

ENGLISH

Exam Schedule

Qualifications assessment

day	07/07/2025
notes	none
publication on notice board	NO
publication on the web site	Yes
web site	(https://phd.uniroma1.it/web/BIOLOGIA-UMANA-E-GENETICA-MEDICA_nD3490.aspx)
date of publication	07/07/2025
contacts	oriana.dangelogargano@uniroma1.it; laura.stronati@uniroma1.it

Oral interview

day	10/07/2025
notes	none
time	09:00
classroom	aula 101
address	Viale Regina Elena 295/Edificio D
publication on notice board	NO
publication on the web site	Yes
web site	https://phd.uniroma1.it/web/BIOLOGIA-UMANA-E-GENETICA-MEDICA_nD3490.aspx
date of publication	10/07/2025
contacts	oriana.dangelogargano@uniroma1.it; laura.stronati@uniroma1.it

Evaluation scale

Qualifications assessment

Valutazione titoli

Punteggio massimo complessivo per la prova/overall max score: 40

Voto di laurea
University final degree mark

Punteggio massimo/max score: 20
Voto di laurea
University final degree mark

110, 110 e lode 110, 110 cum laude	20,0
109 -108 109 -108	18,0
107 -106 107 -106	15,0
105 -104 105 -104	12,0
103 -102 103 -102	8,0
<102 <102	2,0

Gli studenti che discuteranno la tesi prima della data stabilita per la valutazione dei titoli sono tenuti a comunicare al Coordinatore del corso o al Presidente della Commissione il voto di laurea conseguito, mentre per coloro che discuteranno la tesi dopo la data stabilita per la valutazione dei titoli, ma comunque prima del 31 ottobre 2025, la griglia del voto di laurea è sostituita dalla seguente:
Students who have not obtained their title by the application deadline (or graduands who will obtain the degree by October 31st, 2025) will be evaluated on the average grade resulting from the list of the exams:

29 - 30 29 - 30	20,0
28 – 28.99 28 – 28.99	18,0
27 - 27.99 27 - 27.99	15,0
26 - 26.99 26 - 26.99	12,0
25 - 25.99 25 - 25.99	8,0
<25 <25	2,0

Pubblicazioni
Publications

Punteggio massimo/max score: 15
Pubblicazioni
Publications

Pubblicazione ISI (primo autore) ISI (author)	7,0
Pubblicazione ISI (co-autore) ISI (co-author)	3,0
Libro o Capitolo di libro (solo autore) Book or chapter in book (author)	3,0
Libro o Capitolo di libro (co-autore) Book or chapter in book (co-author)	1,0
Contributo a convegno Contribution to a lecture/ congress	1,0

Esperienze di ricerca
Research experiences

Punteggio massimo/max score: 5
Esperienze di ricerca
Research experiences

Esperienze all’estero (almeno due mesi, compreso Erasmus) Experience abroad (at least 2 months, including Erasmus)	2,5
Contratti di collaborazione alla ricerca Collaboration contracts	2,0
Corsi di formazione alla ricerca Training courses for researchers	0,5

Oral interview

Prova orale

Punteggio massimo complessivo per la prova/overall max score: 80

Prova orale
Interview

Punteggio massimo/max score: 80
Prova orale
Interview

Discussione delle tematiche relative al progetto di ricerca Discussion of topics related to the research project	20,0
Conoscenza di base sulla biologia cellulare/molecolare e genetica generale/medica Basic knowledge of molecular/cell biology and genetics/medical genetica	30,0
Discussione sull’esperienza pregressa, sulle competenze tecniche acquisite e sulla capacità di padroneggiarle Discussion about the curriculum, previous experience, and technical skills	25,0
Lingua straniera Foreign language	5,0