Call for application 39th cycle

Bando ordinario (expired 22/06/2023)


Educational goals and objectives

GENETICS AND MOLECULAR BIOLOGY
In the last years there has been a great development of Genetics and Molecular Biology. These two disciplines have progressively exchanged conceptual categories and experimental methods, reaching an integration that represents the central and unifying theme of modern biology. This has created new areas of basic and applied research and expanded existing ones. This determined a strong demand for specialists in this field, able to conduct high-level research at universities, research centres and industry.
Genetics, born as a science referred to the analysis of heredity, has quickly evolved to the study of structure and function of the hereditary material. This led genetics to become an essential component of almost every area of biology, as well as a discipline with a strong power in integrating different fields of biology. The results obtained in the first decades of this century have established that the genetic composition of an organism not only determines the various levels of phenotypic organization, but also how they interact with the environment in which it lives.
Molecular biology in the last 40 years has made it possible to clarify the chemical/physical bases of many biological processes. The structure of the gene and its mode of replication, transcription and translation are now well known in their molecular details. More recently, "omics" methodologies have allowed studying the whole genome, transcriptome and proteome structure allowing the study of cell functions at a more global level. Moreover, the recent technologies of genetic engineering have provided a powerful means of investigation that made it possible to overcome those limits that were considered insurmountable until a few years ago by the very nature of biological systems studied.

Specifiche economiche

Tipologia 1: DM118
Transizione digitale Generiche Pubblica Amministrazione Patrimonio culturale
0 3 0 0

Tipologia 2: DM117 Tipologia 3: PE/PNC/CN/TP Tipologia 4:Enti terzi
PE/PNC CN/TP
0 0 0 2 (+1)*

Tipologia 5: Sapienza Senza borsa
4 2

* Dopo la pubblicazione del bando è stata finanziata 1 borsa da parte di ISS sulla tematica: "Analisi molecolare del microambiente tumorale nel glioblastoma" in relazione al progetto EraPerMed "Improving personalised glioblastoma care by intertwined immunomics and artificial intelligence approaches"

Tematiche, curriculum e competenze specifiche
Themes, curriculum and specific competence

C_PNRR - DM118 GENERICHE - non associata a curriculum

- RNA non codificanti e modifiche dell'RNA come nuovi bersagli per le terapie a base di RNA
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Non-coding RNAs and RNA modifications as novel targets for RNA therapeutics
Founded by: PNRR
Required skills: no specific skill required

C_PNRR - DM118 GENERICHE - non associata a curriculum

- Cause e conseguenze dell'instabilità genomica
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Understanding the causes and consequences of genome instability.
Founded by: PNRR
Required skills: no specific skill required

C_PNRR - DM118 GENERICHE - non associata a curriculum

- Identificazione di tratti genetici per adattare la crescita di piante di interesse agronomico allo stress abiotico
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Identification of important genetic traits to adapt crops growth to abiotic stress
Founded by: PNRR
Required skills: no specific skill required

F - ENTI TERZI - non associata a curriculum

- Caratterizzazione dei meccanismi molecolari causativi di malattie rare associate a nuove mutazioni di geni della superfamiglia di RAS
Ente finanziatore: ISTITUTO SUPERIORE DI SANITA'
Competenze richieste: nessuna competenza specifica richiesta
- Molecular characterization of the pathogenetic mechanisms underlying rare diseases caused by novel mutations in RAS superfamily genes
Founded by: ISTITUTO SUPERIORE DI SANITA'
Required skills: no specific skill required

F - ENTI TERZI - non associata a curriculum

- Analisi molecolare del microambiente tumorale nel glioblastoma
Ente finanziatore: ISTITUTO SUPERIORE DI SANITA'
Competenze richieste: nessuna competenza specifica richiesta
- Analisi molecolare del microambiente tumorale nel glioblastoma
Founded by: ISTITUTO SUPERIORE DI SANITA'
Required skills: no specific skill required

Il candidato sceglierà una tematica in fase di presentazione della candidatura on line

Admission Procedure

Qualifications assessment TITLES (max 35 points)
(1) Academic titles: average grade resulting from the list of the exams (both bachelor and master degree); master degree obtained within the prescribed time period; admission to Schools of Advanced Studies/Excellence Programs.
(2) Scientific titles: publications, national and international research experiences (including Erasmus), research fellowships and grants, training courses.
Written examination WRITTEN EXAMINATION (max 45 points)
Minimum score for admission to the oral examination: 25/45
The candidate may choose one of three topics extracted. The written test is in Italian.
Examples of topics for previous cycles are available on the doctoral course website
language ITALIANO
Oral interview INTERVIEW (max 40 points).
The oral examination consists of two parts: Project presentation and evaluation of the competences. (1) Research project: the candidate must present a project (without the use of media support) coherent with the research lines of the PhD course in Genetics and Molecular Biology (research projects for the 39° cycle are available on the web site). Evaluation will be based on: clarity of the presentation and knowledge of the state of the art; originality and innovation of the content; project feasibility; pertinence of the project with the PhD course objectives. Please note that a written project is NOT requested. (2) Evaluation of the candidate’s knowledge on general topics inherent to genetics and molecular biology. The interview will be followed by a test aimed to verify the candidate’s knowledge of the English language. The test will consist in reading and translating a paragraph of a scientific article in English on a topic related to the themes of the doctorate.

Minimum global score for admission to the PhD programme: 80/120
language INGLESE
ITALIANO

contacts and info Fulvio Cruciani (coordinatore) fulvio.cruciani@uniroma1.it Silvia Lopizzo (segreteria) silvia.lopizzo@uniroma1.it
more info Please note that the written examination is in Italian, no other languages are allowed.

Curriculum studiorum

Graduation date and grade of the Master's degree
detailed list of exams including completion dates and scores of Masters's degree
Graduation date and grade of the Bachelor’s degree
detailed list of exams including completion dates and scores of Bachelor's degree
History of Scholarships, Research Grants (or similar)
Certificates of Foreign Languages
Certificates of participation in post-graduate university courses
certificates of Participation in research groups
certificates of Participation in internships
Other University Awards/Degrees (e.g.: awards in competition, second degree)
Computer skills

Required documentation

§ List of publications
optional
Only publications (articles, reviews, conference abstracts, book chapters, etc.) included in this list will be taken into account for the evaluation of the titles regarding scientific production., the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ other document: Certificate of admission to academic excellence programs or Schools for Advanced Studies
optional
Self-certification admitted, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ other document: Self-certification master degree within prescribed time
mandatory
Candidates must upload a self-certification which clearly states whether or
not they have obtained (or will obtain if they are undergraduates) their master
degree within the scheduled time foreseen to complete the course., the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)

Language Skills

the candidate must know the following languages
ENGLISH

Exam Schedule

Qualifications assessment
day03/07/2023
notesnone
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/GENETICA-E-BIOLOGIA-MOLECOLARE_nD3506.aspx
date of publication07/07/2023
contactsSilvia Lopizzo (silvia.lopizzo@uniroma1.it); Fulvio Cruciani (fulvio.cruciani@uniroma1.it)

Written examination
day13/07/2023
notesnone
time09:30
classroomAula Pasquini, Edificio di Zoologia CU008
address Viale dell'Università 32, 00185 Roma
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/GENETICA-E-BIOLOGIA-MOLECOLARE_nD3506.aspx
date of publication17/07/2023
contactsSilvia Lopizzo (silvia.lopizzo@uniroma1.it); Fulvio Cruciani (fulvio.cruciani@uniroma1.it)

Oral interview
day20/07/2023
notesnone
time09:30
classroomAula Serra 1, Edificio di Genetica CU022
addressPiazzale Aldo Moro 5, 00185 Roma
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/GENETICA-E-BIOLOGIA-MOLECOLARE_nD3506.aspx
date of publication24/07/2023
contactsSilvia Lopizzo (silvia.lopizzo@uniroma1.it); Fulvio Cruciani (fulvio.cruciani@uniroma1.it)

Evaluation scale

file:visualizza il file
file (eng):visualizza il file (eng)

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma