Riboregulation from bacteria to eukaryotes: mechanisms and challenges.


The aim of this one-day workshop is to gather attention on the novel role of RNA as regulator of protein activity and its importance in the control of cellular metabolism. Understanding the molecular details of RNA-protein interactions and the effect on cellular physiology is a key step to exploit the impact of these discoveries to fundamental science and to translational applications in the field of RNA therapeutics

21/06/2023

WORKSHOP PROGRAMME

08:30 Registration

SECTION I - MORNING

09:00 Welcome address

09:15 MATTHIAS HENTZE (EMBL, DE): Riboregulation: Biology, Mechanisms and Scope

10:00 INA HUPPERTZ (MAX PLANCK, COLOGNE, DE):
Controlling Stem Cell Fate and Metabolism: The Power of Riboregulation of Enolase 1’s Activity

10:40 Coffee break

11:10 BEN LUISI (UNIVERSITY OF CAMBRIDGE, UK): Dynamic ribonucleoprotein complexes in the control of bacterial gene expression

11:50 GIAN GAETANO TARTAGLIA (IIT, IT): Predictions of RNA-binding ability of proteins

12:40 FRANCESCA CUTRUZZOLA' (SAPIENZA UNIVERSITY OF
ROME, IT): Riboregulation of serine hydroxymethyltransferase controls serine metabolism
across cellular compartments

SECTION II - AFTERNOON

15:00 ROUNDTABLE: Riboregulation: future challenges for fundamental research and RNA therapeutics

16:30 Concluding remarks

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