Call for application 39th cycle

Bando ordinario (expired 22/06/2023)


Educational goals and objectives

MORPHOGENESIS AND TISSUE ENGINEERING
The Ph.D. program in Morphogenesis and Tissue Engineering is part of the School of Doctorate in Biology and Molecular Medicine. The overall aim of the Ph.D. program is to provide cultural, analytical and methodological tools and analytical tools to perform high level-, basic- or traslational- or applied-, research in the biomedical and biotechnological fields.
For this purpose, the courses are aimed to teach the students not only notions (rapidly changing and evolving) but also to acquire evaluation criteria to innovatively pinpoint unresolved issues, in specific fields and to design experimental strategies which address these issues.
The educational aims of the Ph.D. program are developed through research guidelines regarding the study of the mechanisms regulating cell differentiation, tissue homeostasis, regeneration and the physiopathology of different tissues. In particular, the research interests are distributed in three main curricula:

Curriculum in Morphogenetic and Cytological Sciences:
Progression and maintenance of the differentiated state, through interaction between muscle cells and factors regulating histogenesis, homeostasis and tissue regeneration;
Identification of molecular mechanisms of cell differentiation;
Tissue engineering to mimic neo-organogenesis to produce ex vivo living tissue and to study cell–cell interactions, stem cell–matrix interactions and the role of tissue niche on stem cells behavior;
Molecular mechanisms of tissue remodeling and homeostasis
Stem cells and regenerative medicine

Curriculum in Cell Sciences and Technologies. The main areas of training for this curriculum are:

Mechanisms controlling cell cycle and death, a primary interest being devoted to the study of molecular regulators of the intrinsic and extrinsic apoptosis pathways.
isolation and characterization of mammalian germline stem cells, prerequisite for their potential use in medical therapy of infertility and of testis germ cell tumors.
Tissue homeostasis and malignant transformation: interplay between tissue homeostasis changes induced by inflammatory agents and carcinogenesis or tumor progression in hyperplasic and carcinoma cells and in "in vivo" mouse models of orthotopic- and xenotransplants; cross talk between signal pathways activated by receptors of innate immunity and oncogenes in the onset of transformed phenotype; immunosuppressive mechanisms developed by tumour cells and strategies to restore anti-tumour immunosurveillance.

Curriculum in Cell and Tissue Biophysics focus in the following fields:
mathematical modeling, multivariate statistics and biophysical chemistry;
spectroscopical methods;
human biology, molecular genetics and brain metabolism;
dynamical simulations and modeling of biosystems at different dimensional scale.

Specifiche economiche

Tipologia 1: DM118
Transizione digitale Generiche Pubblica Amministrazione Patrimonio culturale
0 3 0 0

Tipologia 2: DM117 Tipologia 3: PE/PNC/CN/TP Tipologia 4:Enti terzi
PE/PNC CN/TP
0 0 0 1

Tipologia 5: Sapienza Senza borsa
6 2

Tematiche, curriculum e competenze specifiche
Themes, curriculum and specific competence

C_PNRR - DM118 GENERICHE - sul curriculum: BIOFISICA CELLULARE E TISSUTALE

- Neuromarker neurofisiologi relativi alla promozione di messaggi e comportamenti ecologicamente responsabili
Ente finanziatore: PNRR
Competenze richieste: competenze in neurofisiologia
- Neurophysiologic neuromarker related to the promotion of messages and behaviors environmentally responsible.
Founded by: PNRR
Required skills: skills in neurophysiology

C_PNRR - DM118 GENERICHE - sul curriculum: SCIENZE MORFOGENETICHE E CITOLOGICHE

- Identificazione di bersagli terapeutici per indurre la morte cellulare dei progenitori mieloidi trasformati superando gli effetti protettivi delle cellule mesenchimali della nicchia midollare.
Ente finanziatore: PNRR
Competenze richieste: Competenze in biologia cellulare e molecolare
- Identification of therapeutic targets to induce transformed myeloid progenitors cell death overcoming the protective effects of the bone marrow niche mesenchymal cells.
Founded by: PNRR
Required skills: Expertise in cellular and molecular biology

C_PNRR - DM118 GENERICHE - sul curriculum: SCIENZE E TECNOLOGIE CELLULARI

- Approccio olistico nello studio degli effetti della gravità alterata su linee cellulari germinali maschili umane utilizzando tecnologie avanzate
Ente finanziatore: PNRR
Competenze richieste: Competenze in biologia cellulare e molecolare
- Holistic approach in the study of the effects of altered gravity on human male germ cell lines by using advanced technologies
Founded by: PNRR
Required skills: Expertise in cellular and molecular biology

F - ENTI TERZI - non associata a curriculum

- L’inibizione dei miR-4488 e miR-4443 come nuova strategia per ridurre il potenziale metastatico del melanoma
Ente finanziatore: IFO - IRE
Competenze richieste: Competenze in tecniche di biologia cellulare e molecolare; competenze in oncologia molecolare
- Inhibiting miR-4488 and miR-4443 as a new strategy to tackle the metastatic potential of melanoma
Founded by: IFO - IRE
Required skills: skills in cell and molecular biology; expertise in molecular oncology

Il candidato sceglierà una tematica in fase di presentazione della candidatura on line

Admission Procedure

Qualifications assessment Candidates wishing to apply for a PhD position can find information on the procedures, methods, and deadlines by connecting to the Sapienza website (https://www.uniroma1.it/it/pagina/dottorati-di-ricerca) Call for applications of XXXIX cycle.
The qualifications are estimated according to the evaluation criteria defined by the Doctoral Teaching Council (the evaluation grid is available in the call for applications):
1. Academic titles and transcripts (graduation date and score, detailed exams, grades).
2. Curriculum vitae. Please clearly indicate research experience, acquired technical skills, publications, and other qualifications that the candidate may consider useful for the purposes of evaluation, scholarships, research training courses, research collaboration contracts.
3. Letter of motivation. The candidate must indicate the reasons for the choice to apply to the MIT PhD program, must briefly describe the previous research experience, the acquired technical competences / skills and future scientific interests.
4. Letter(s) of recommendation supporting the candidate. It should be clear from the letter why the reviewer is able to evaluate the candidate.
There is no minimum qualification score for admission to the oral exam.
Oral interview Oral examination consists in:
a) A 12- to 15-minute presentation, in front of the Commission, related to the experimental work conducted during the preparation of the thesis, or other experimental work, or of a research project selected by the candidate among the topics of the MIT PhD program. The evaluation will consider the clarity and completeness of the presentation, the way in which the various sections are balanced (identification of scientific problem and state of the art, experimental methodology, results, conclusions). In the case a research project is presented, the Commission will assess its originality and feasibility, the clarity and completeness of the aims presented, of the methodologies and of the potential results.
b) Discussion of the contents of the presentation.
c) Other topics selected by the Commission from among those that are inherent to the cultural topic of the PhD course.
d) Assessment of level of English.

The schedule of the oral exam will be published on the PhD course website: https://phd.uniroma1.it/web/MORFOGENESI-E-INGEGNERIA-TISSUTALE_nD3525_IT.aspx
language ITALIANO

contacts and info Per informazioni: dottoratomit.saimlal@uniroma1.it sito web: https://phd.uniroma1.it/web/MORFOGENESI-E-INGEGNERIA-TISSUTALE_nD3525_IT.aspx
more info For further information: dottoratomit.saimlal@uniroma1.it
Evaluation criteria are those detailed in the call and website

Curriculum studiorum

Graduation date and grade of the Master's degree
detailed list of exams including completion dates and scores of Masters's degree
Graduation date and grade of the Bachelor’s degree
History of Scholarships, Research Grants (or similar)
Certificates of Foreign Languages
Certificates of participation in post-graduate university courses
certificates of Participation in research groups
certificates of Participation in internships
Other University Awards/Degrees (e.g.: awards in competition, second degree)
Computer skills

Required documentation

§ degree thesis abstract
mandatory
The candidate must provide a page abstract of its thesis organized in the following points:
- RATIONALE
- PRELIMINARY DATA
- BROAD OBJECTIVES
- PROJECT DESIGN AND METHODS
- EXPECTED RESULTS, da caricare entro la scadenza del bando,, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ first letter of introduction (by a teacher)
mandatory, the letter must be uploaded by the candidate
Recommendation letters should be provided ONLY in the format present on the PhD website (File name
RECOMMENDATION LETTER)., the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ List of publications
optional
The candidate can submit the list of indexed publications on PubMed/ISI/Scopus, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ letter of motivation (by the candidate)
mandatory
The cover letter should include the following points:
- Explain the reasons that prompted you to apply for this PhD program
- What are your career plans and what do you plan to do right after your PhD?, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ degree thesis (complete)
mandatory
Provide the PDF of master thesis, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)
§ Curriculum Vitae et Studiorum
mandatory
Clearly indicate the professional training (only relevant activities), research experience, acquired technical skills,
publications and other qualifications that the candidate considers useful for the purposes of evaluation,
scholarships, research training courses, research collaboration contracts, etc.,, the file must be uploaded within 22/06/2023 ore 14:00 (ora italiana)

Language Skills

the candidate must know the following languages
ENGLISH

Exam Schedule

Qualifications assessment
day03/07/2023
notesLa commissione, sulla base del numero delle domande pervenute, può riunirsi per la valutazione dei titoli in più giorni.
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/MORFOGENESI-E-INGEGNERIA-TISSUTALE_nD3525.aspx
date of publication14/07/2023
contactsdottoratomit.saimlal@uniroma1.it

Oral interview
day17/07/2023
notesLa commissione, sulla base del numero dei candidati ammessi alla prova orale fornirà un calendario dei giorni di convocazione dei candidati. La prova orale, per chi fosse impossibilitato a svolgerla in presenza, potrebbe essere svolta da remoto, comunicando la propria impossibilità alla commissione e all'indirizzo email del dottorato MIT.
time09:00
classroomAula Monesi
addressSezione di istologia ed Embriologia Medica; Via A. Scarpa 14
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/MORFOGENESI-E-INGEGNERIA-TISSUTALE_nD3525.aspx
date of publication31/07/2023
contactsdottoratomit.saimlal@uniroma1.it

Evaluation scale

file:visualizza il file
file (eng):visualizza il file (eng)

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