Phd in MORPHOGENESIS AND TISSUE ENGINEERING

List of courses / activities for the first year

More information The doctorate organizes a series of courses with the aim of providing PhD students with advanced training in the fields of basic and translational research. A series of seminar activities will also be programmed, moderated and organized by the members of the teaching body, on the various research topics relevant to the educational objectives of the PhD, such as: Genetic and epigenetic regulation in cell differentiation, development and pathological conditions. Cellular and molecular mechanisms of tissue regeneration. Regulation of angiogenesis and calcium signaling in human endothelial cells and tumor progression. Epigenetic regulation of the genesis and progression of prostate cancer induced by inflammatory stimuli. Mechanisms of regulation of the immune response. Signal transduction mechanisms in tissue remodeling. Tissue homeostasis. Molecular mechanisms of muscle atrophy and hypertrophy. Molecular mechanisms activated by physical exercise and exercise-mimetic drugs. Tissue engineering. Regenerative medicine. Application of physical methods and techniques to the study of interactions between nanocarriers for the delivery of drugs and nucleic acids in target cells. Use of brain-computer interfaces for communication between subjects and electronic devices. Study of cortical activity during cognitive tasks in humans. Method of choosing the subject of the thesis The subject of the thesis is planned between tutor and PhD student, presented and discussed in front of the teaching body (CdD), as a research PROJECT, and approved by the CdD Admission to the second year Each doctoral student presents the research project at the beginning of the academic year. At the end of the AA, the doctoral student presents the results obtained during the year to the Board of Directors through an oral presentation and a report in English. The activity of each doctoral student is evaluated taking into consideration the following parameters: - motivations, - work commitment, - autonomy in carrying out the experimental activity, - culture and scientific updating, - interactivity with the environment, - design skills, - critical ability and participation in scientific discussions, - accomplished results, - publications.

List of courses / activities for the second year

More information The Ph.D. course organizes a series of activities, such as the theoretical-practical Bioinformatics course, the statistical methods course, the drug discovery & delivery course, the research integrity course, etc., with the aim of providing PhD students with advanced training in the fields of basic research and translational medicine. A series of seminar activities will also be scheduled, held by Italian and foreign professors and researchers, on topics not only specific to the PhD curricula, but also transdisciplinary. The goal is to promote and provide PhD students with an innovative and competitive academic program, aimed at stimulating their critical spirit and propensity to face the complexity of knowledge. For details of the activities, consult the links in the section: "Insights" Method of preparation of the thesis Defined by tutor and PhD student, approved by the CdD: Experiment planning; Experimental activity; Evaluation and interpretation of the results; Discussion of the experimental results in periodic lab-meetings; Preparation of communications at congresses. Admission to the third year Each PhD student presents the research project and any preliminary results in the spring. At the end of the academic year, the PhD student presents the results obtained during the year to the CdD through an oral presentation and a report in English. The activity of each PhD student is evaluated taking into consideration the following parameters: - motivations, - work commitment, - autonomy in carrying out the experimental activity, - culture and scientific updating, - interactivity with the environment, - design skills, - critical ability and participation in scientific discussions, - accomplished results, - publications.

List of courses / activities for the third year

More information The PhD course organizes a series of theoretical-practical courses, such as Scientific writing, ethics of scientific research, data patentability, etc., with the aim of providing doctoral students with advanced training in the areas of basic and translational research and the importance of ethics and scientific rigor. A series of seminar activities will also be organized on the following topics: Experimental models for the study of homeostasis and tissue regeneration. Tissue engineering. Plasticity and tissue identity. The basics of cell differentiation. Signals and factors of cell differentiation. The evolution of regenerative bio-medicine. In the third year, the preparation of the thesis contributes to the training activities. Teaching activities (not institutional courses): Tissue engineering and stem cell biology; elements of bioinformatics Research related activities: Didactic activities (not institutional courses): Embryogenesis and Histogenesis, Regulation of the cell cycle and apoptosis, Safety elements in the laboratory, Practical-training research activity (see scientific reports), Educational and research activities independently chosen by the student and approved by the Academic Board, Participation (active / passive) in national and international conferences (e.g .: Conference organized by BEMM students; Annual conferences ABCD, SIB and IIM, etc.). For details of the activities, consult the links in the section: "Insights" Method of admission to the final examination In the spring, the PhD students present the results obtained in previous years and report the progress of the preparation of the thesis. Oral presentation of the thesis in English to the CdD accompanied by a draft of the final thesis (in English). The thesis is submitted to external reviewers chosen by the Academic Board. Based on the evaluations of the external reviewers, on the presentation and final discussion of the thesis with the answers given to the evaluators' comments, on the evaluation of the entire doctoral curriculum, the Board of Professors decides on the admission of the doctoral students to the final exam for the achievement of the PhD title. Final examination Critical review of the thesis by at least 2 External reviewers, each of them presenting a written report. Presentation and discussion of the thesis in front of the CdD. Evaluation of the opinions of external reviewers. The CdD evaluate and approves the presentation of the student and the research activity carried out. Submission of the thesis in final form and discussion of the thesis in front of the examination board.