Call for application 39th cycle

Bando ordinario (expired 22/06/2023)


Educational goals and objectives

BIOCHEMISTRY
The PhD in Biochemistry is rather unique among the bio-molecular and biomedical PhD programmes. The major educational aim of this programme is to form young scientists able to figure out biochemical problems on the frontier of biology and medicine. At the end of the Course, the biochemistry PhD students are expected to be able to recognise the existence of open questions, to frame them within the current scientific knowledge, and related international literature, and to propose ways of experimentally approaching them. In this respect, these students are expected to design experiments and protocols suitable to solve or at least to correctly approach the problems, also making use of most advanced experimental tools available. Thus, their cultural and scientific background is considered of paramount importance together with high level continuous practical bench-training, both needing to be as vast and profound as possible; all specializations being achieved only at latest stages and always as a finalised part of the Programme.
Most of these young scientists are called to cope with oral presentations in scientific meetings of national/international level.
All above is ideally achieved during 3 years courses whereby every student experiences, individually, the possibility of carrying out his own research. The acquisition of the theoretical and the practical knowledge proceeds in parallel in such a way to optimise the growth of the young biochemical scientist.
The overall process is supervised by a Tutor and typically in one of the bio-molecular and biotechnological areas operative in the Department of Biochemical Sciences, namely:
Cellular Biochemistry and Physiology
Basic Biochemistry
Protein Chemistry
Calcium signalling and signal transduction
Amidohydrolases
Antioxidants
Oxidative stress and carcinogenesis
Pyridossal-phosphate Enzymes
Inorganic Biochemistry
Aminoxidases
Nitric Oxide & Nitrite reductases in eukaryotes and prokaryotes
Fe transport & storage
Molecular Biology and Biophysics
Enzymology
Globins
Proteins, DNA & nuclear cromatin
Viral genome
Terminal Oxidases & Bioenergetics
Thermodynamics of Conformational Stability
Structural Biology
Biocristallography
Protein Folding
Proteomics & Peptidomics
Bioinformatics
Structural Dynamics
Biotechnology
Bacterial & Vegetal toxins
Bioactive peptides & Immunity
Proteins & Enzymes from extremophyles
Protein - haemoglobin engineering
Engineering of hemoglobin as a blood substitute
Bio active compounds of pharmacological interest.

Specifiche economiche

Tipologia 1: DM118
Transizione digitale Generiche Pubblica Amministrazione Patrimonio culturale
0 3 0 0

Tipologia 2: DM117 Tipologia 3: PE/PNC/CN/TP Tipologia 4:Enti terzi
PE/PNC CN/TP
0 0 0 0

Tipologia 5: Sapienza Senza borsa
5 2

Tematiche, curriculum e competenze specifiche
Themes, curriculum and specific competence

C_PNRR - DM118 GENERICHE - non associata a curriculum

- Sviluppo di sistemi di trasporto mirato di sostanze attive come farmaci
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Development of targeted transport systems of active substances such as drugs
Founded by: PNRR
Required skills: no specific skill required

C_PNRR - DM118 GENERICHE - non associata a curriculum

- Approcci innovativi per l’identificazione e ottimizzazione di nuovi agenti terapeutici per il trattamento di malattie infettive e genetiche
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Innovative approaches to identify and optimize new therapeutic agents for the treatment of infectious and genetic diseases
Founded by: PNRR
Required skills: no specific skill required

C_PNRR - DM118 GENERICHE - non associata a curriculum

- Approccio integrato di metabolomica e proteomica nello studio di patologie complesse
Ente finanziatore: PNRR
Competenze richieste: nessuna competenza specifica richiesta
- Integrated metabolomics and proteomics approach in the study of complex pathologies
Founded by: PNRR
Required skills: no specific skill required

Il candidato sceglierà una tematica in fase di presentazione della candidatura on line


Admission Procedure

Qualifications assessment The evaluation of qualifications will concern only the graduate degree grade. If the candidate is waiting to graduate - still within 10/31/2023 - the average of the exam marks will be used.

Written examination Description of the test: the written test consists of a paper on a topic of general biochemistry, extracted from three tracks prepared by the Commission. The paper will be evaluated by the Commission on the basis of the congruity with the subject matter of the test, the clarity and the completeness of the discussion.
language ITALIANO

Oral interview Description of the test: candidates who have passed the written test must sit an interview with the Selection Committee.
During this interview the Commission will proceed to:
1) a discussion with the candidate of the written test
2) verification of the candidate's general scientific culture and of his/her aptitude to tackle laboratory research both from a theoretical and methodological point of view, evaluating
the clarity, the mastery and the specific competence on the subject treated
3) assessment of the degree of knowledge and fluency of the English language.

Candidates admitted to the oral exam must present themselves with a declaration which certifies, under their own responsibility, all the exams taken with the relative marks and the subject of their degree thesis.
language ITALIANO


contacts and info Per tutte le informazioni: https://phd.uniroma1.it/web/pagina.aspx?i=3487&l=IT&p=726 Prof. Francesco Malatesta Tel: 06 49910943 email: francesco.malatesta@uniroma1.it
more info Recommended texts:
J. Voet, D. Voet, & C.W. Pratt, Fundamentals of Biochemistry: Life at the Molecular Level (Wiley)
D.L. Nelson & M.M.Cox, Lehninger Principles of Biochemistry (Freeman & Co)

Curriculum studiorum

Graduation date and grade of the Master's degree
detailed list of exams including completion dates and scores of Masters's degree

Required documentation

Language Skills

the candidate must know the following languages
ITALIANO
ENGLISH

Exam Schedule

Qualifications assessment
day04/07/2023
notesnone
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/pagina.aspx?i=3487&l=IT&p=726
date of publication04/07/2023
contactsfrancesco.malatesta@uniroma1.it

Written examination
day05/07/2023
notesnone
time13:00
classroomA - CU010
addressPiazzale Aldo Moro 5, 00185 Roma
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/pagina.aspx?i=3487&l=IT&p=726
date of publication12/07/2023
contactsfrancesco.malatesta@uniroma1.it

Oral interview
day13/07/2023
notesnone
time09:00
classroomA1 -CU010
addressPiazzale Aldo Moro 5, 00185 Roma
publication on notice boardNO
publication on the web siteYes
web sitehttps://phd.uniroma1.it/web/pagina.aspx?i=3487&l=IT&p=726
date of publication14/07/2023
contactsfrancesco.malatesta@uniroma1.it

Evaluation scale

file:visualizza il file
file (eng):visualizza il file (eng)

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