Progress Report Incontri in cui gli studentə del 2° e 3° anno espongono l'avanzamento delle loro ricerche 17 gennaio 2025 Docenti: Trombetta (chair), Bozzoni, Presutti, Raffa, ADV Arbitri: Biagi, Cannistrà, Simula, Spurio Maria Chiara Barone: “Molecular characterization of the pathogenetic mechanisms underlying different diseases caused by novel mutations related to the RAS superfamily genes” Clelia Cortile: “Epigenetic profiling of Multiple Myelomainitiation and progression” Michela De Nittis: “Unveiling Auxin Minimum-responsive Genes Triggering the Division-to-Differentiation switch in Arabidopsis thaliana Root Apical Meristem” 31 gennaio 2025 Docenti: Cacchione (chair), Ciapponi, Dello Ioio, Fanti, ADV Arbitri: Cappelletto, Corda, Tesoriere, Silvestri Diego Ferreri: “From nucleus to centrosome: the “mitotic trip” of MRG15, a moonlighting protein involved in Drosophila cell cycle regulation” Raffaele Garraffo: “The role of the dsRBP STAU1 in circRNA-mRNA interactions” Sara Gualdi: "Immunological analysis of the tumor microenvironment in glioblastoma” 14 febbraio 2025 Docenti: Giunta (chair), Laneve, Tartaglia, Serino, ADV Arbitri: De Santis, Di Tommaso, Santopietro, Cortile Maria Chiara Cappelletto: “Characterization of epigenetic variations of human Multiple Myeloma: the involvement of NRF1” Damiano Guerrini: “The role of trascriptional stress in Spinal Muscolar Atrophy” Letizia Pistacchia: "Population genomics of Asiatic lion: a whole genome sequencing approach for preserving the biodiversity of an endangered species” 28 febbraio 2025 Docenti:Fatica (chair), Cruciani, Sabatini, Piacentini, ADV Arbitri: Grazzi, Lepri, Barone, De Nittis Sofia Silvestri: “Spatial Optimization and Genetic Approaches for the Identification of Key Biodiversity Areas” Marco Simula: “Long noncoding RNA at the interface between muscle and nerve” Alessia Spurio: “Investigating centromere instability in human cancer” 07 marzo 2025 Docenti: Dimitri (chair), Guarguaglini, Raimondo, Vernì, ADV Arbitri: Mastrangelo, Medici, Ferreri, Garraffo Maria Chiara Biagi: “Engineering circular RNAs for efficient protein production” Fabio Piscopo: “Unveiling the role of PCIF1 methyltransferase in Triple- Negative Breast Cancer (TNBC).” 28 marzo 2025 Docenti: Ballarino (chair), Lavia, Trombetta, Fanti, ADV Arbitri: Menicucci, Riesle, Risi, Gualdi, Guerrini Luca Corda: "Genetic and epigenetic changes in the repetitive regions of the human genome" Lucrezia De Santis: "Dissecting the role LINC00504 and LINC00520 in melanoma phenotype switching" 04 aprile 2025 Docenti: Dello Ioio (chair), Laneve, Ciapponi, Giunta, ADV Arbitri: Santopietro, Tarullo, Piscopo, Pistacchia Elena Di Tommaso: "Understanding the role of CENP-A in modulating responses to DNA damage and R-loops formation in human cancers" Federica Cannistrà: "Role of the nuclear envelope in physiological and pathological conditions” 09 maggio 2025 Docenti: Serino (chair), Cacchione, Vernì, Bozzoni, ADV Arbitri: Tesoriere, Vrachnos, Silvestri, Simula Alessandro Grazzi: "CyCoNP lncRNA sustains NCAM1 expression by RNA-RNA direct binding to control human motor neuron specification." Andrea Lepri: “Unveiling the signaling pathway of light-independent seed germination". 16 maggio 2025 Docenti: Presutti (chair), Cruciani, Ballarino, Tartaglia, ADV Arbitri: Biagi, Spurio, Barone, Cortile Anna Mastrangelo: “Investigation of the mechanisms regulating AurkA nuclear localization” Margherita Medici: “Targeting the RNA-binding protein HuD (ELAVL4) to control ALS disease" 30 maggio 2025 Docenti: Lavia (chair), Fatica, Piacentini, Dimitri, ADV Arbitri: Cannistrà, De Santis, De Nittis, Ferreri Giulia Menicucci: "High resolution NGS approach for non invasive detection of somatic mutations in solid tumors" Aileen Julia Riesle: “Epigenetic mechanisms regulating monogenic expression of Olfactory Receptor genes” 06 giugno 2025 Docenti: Raimondo (chair), Dello Ioio, Saggio, Laneve, ADV Arbitri: Di Tommaso, Grazzi, Garraffo, Gualdi Flavia Risi: "Echoes from the last Green Sahara: whole genome analysis of Fulani, a key population to unveil the evolutionary history of Africa" Maria Virginia Santopietro: "Moonlighting roles of chromatin-remodeling proteins in cell division". 13 giugno 2025 Docenti: Guarguaglini (chair), Raffa , Sabatini, Cacchione, ADV Arbitri: Lepri, Mastrangelo, Guerrini, Piscopo MarcoTarullo: "FTO targeting by chemical inhibition as a strategy against chronic myeloid leukemia” Giulia Tesoriere: "Role of Vitamin B6 in cancer using Drosophila as a model system". Dimitrios Miltiadis Vrachnos: “A new theoretical framework to predict phase separation”.