Various Lewis acids have been developed as green catalysts for asymmetric
synthesis. Chiral metal complexes derived from bismuth, iron, and copper salts have been
employed in selected asymmetric C–C, C–Si, C–N, and C–S bond-forming reactions, such
as the Mukaiyama aldol, epoxide opening, thia-Michael and Diels-Alder reactions.
Enantioselective oxidation catalysts will also be presented.
2 As part of our ongoing interest
in the development of greener reaction conditions, we report alternate reaction solvent
systems. These results will contribute to the development of green acid catalysis for
28/02/2020, 14.30, Sala Parravano