Seminars The seminars are common to the two curricula and will take place from 01/11/2024 to 31/10/2025.Venue, times, date - if not specified - and delivery method will be communicated directly to doctoral students via institutional e-mail. 2025 Workshop on cancer immunotherapy and vaccines 28/05/2025 Fabio Palombo, Alexandre Harari, Laurence Zitvogel, Guido Kroemer, Gennaro Ciliberto, Luigia Pace Germ cell of the testis: from basic research to the clinic 21/05/2025 Elena Vicini, Ewa Rajpert-De Meyts, Sara Di Persio, Francesco Lombardo Misconduct and predatory publishing 14/05/2025 Cinzia Caporale, Enrico Bucci Therapy 3.0 for the treatment of type 2 diabetes mellitus: the medicines of the near future 23/04/2025 A. Giaccari, F. Giorgino, R. Buzzetti, S. Del Prato Gut microbiota and cardiovascular diseases 16/04/2025 Francesco Violi Endogenous DNA Mutator Enzymes at the Crossroad of Virology and Oncology 19/03/2025 Jean-Pierre Vartanian Neural bases of unconscious vision in humans and non-human primates 12/03/2025 Marco Tamietto Host pathogen interaction: lessons from malaria, cytomegalovirus and SARS 05/03/2025 Antonio Lanzavecchia A ‘functionomic’ view of the immune response 26/02/2025 Gioacchino Natoli, Beatrice Bodega, Sergio Abrignani, Giuseppe Macino The role of the lung in autoimmune pathology of the central nervous system 29/01/2025 Francesca Odoardi 2024 Investigating the pathophysiology and therapeutics of vascular Ehlers-Danlos syndrome, a rare genetic arterial disease 18/12/2024 Xavier Jeunemaitre Platelet Activation, Cardiovascular Diseases and Tumours 11/12/2024 Francesca Santilli, Paola Patrignani, Valerio De Stefano Systemic Amyloidosis: an open challenge. From mechanisms to treatments 04/12/2024 Reprogrammed mitochondria as a central hub in cancer cell metabolism: not always the same side of the coin 27/11/2024 Maria Rosa Ciriolo The inflammation as a meta-narration 20/11/2024 Silvano Sozzani, Claudio Franceschi, Alberto Mantovani, Douglas Golenbock Spontaneous brain activity in health and disease 13/11/2024 Maurizio Corbetta 2023 Role of melatonin in the progression of primary sclerosing cholangitis Prof.ssa Mancinelli Non-alcoholic hepatic steatosis and cardiovascular risk. Prof. Del Ben HCC prevention Elastomer evaluation of liver disease. Prof. De Santis Hemodynamic changes in the cirrhotic patient. Prof. Merli Role of lactoferrin in biliary epithelial proliferation Prof. Mancinelli Nutritional, nutraceutical and pharmacological approach in NAFLD/NASH Prof.ssa Del Ben Hepatic encephalopathy. Prof. Riggio Stem cells in pathophysiology and regenerative medicine of the liver and biliary tree. Prof. Cardinale Micro and macro-nodular cirrhosis Prof. Petrozza Update on the functional anatomy units of the liver. Prof. Gaudio Hepatocarcinoma: epidemiology, clinical and therapy. Prof. De Santis Direct and indirect portal pressure measure. Prof. Riggio Liver biopsy: value and prognostic factor in the developmental and proliferative pathologies of the liver. Prof. Petrozza Portal hypertension therapy: AASLD guidelines Prof. Riggio Hepatic masses Prof. Petrozza Mechanisms involved in the pathophysiology of liver lipid metabolism. Prof. Ginanni Corradini Pathophysiology, clinical and therapeutic features of NAFLD/NASH. Prof. Angelico Hemodynamic changes in the course of cirrhosis of the liver and following shunt procedures for the treatment of portal hypertension. Prof. Merli Pharmacological and nutraceutical approach in NAFLD/NASH therapy. Prof. Angelico Diagnostic and clinical therapeutic aspects of NASH Prof. Del Ben Preoperative prognostic factors in liver transplant. Prof. Ginanni Corradini Modern acquisitions on the structure and histo-physiology of the liver. Prof. Gaudio Cholangiocarcinoma: from basic science to bedside. Prof. Alvaro Role of sarcopenia in liver disease and liver-muscle interaction Prof. ssa Merli Liver stem cells: from physiopathology to clinical applications Prof. Alvaro Pathophysiology and diagnostics of portal circulation. Prof. De Santis New acquisitions in regenerative medicine of the liver, biliary tree and pancreas. Prof. Cardinale Polycystic liver Prof. Onori Cellular cross-talk in the pathogenesis of NAFLD. Prof. Carpino Pathogenetic mechanisms of steatosis and hepatic fibrosis evolutionary in HCV infection. Prof. Ginanni Corradini Hepatic role of IGF-I Prof. Franchitto Role of growth factors on the proliferation of cholangiocytes in primary cultures. Prof. Mancinelli Cholangiocyte proliferation in cholestatic and neoplastic pathology Prof. Alvaro Biliary tract. Prof. Franchitto Hepatic circulatory territories: the hepatic segments Prof. Onori Experimental models of cirrhosis Prof. Franchitto Liver and Atherosclerosis Prof. Gaudio