ILARIA BONAVENTURA

PhD Student

PhD program:: XL
email: ilaria.bonaventura@uniroma1.it

supervisor: Prof. Daniele Gianfrilli

Medical Doctor (MD) Specialist in Endocrinology and Metabolic Diseases Focus on adrenal and pituitary disorders, gynecological endocrinology, andrology, and general endocrinology. WORK EXPERIENCE -Nov 2024 – Present: PhD Candidate in Endocrine Sciences, Department of Experimental Medicine – Sapienza University of Rome. -Jan 2021 – Jan 2025: Residency in Endocrinology and Metabolic Diseases, Sapienza University of Rome – Policlinico Umberto I. EDUCATION AND TRAINING -Jan 2021 – Jan 2025: Residency in Endocrinology and Metabolic Diseases, Sapienza University of Rome – Policlinico Umberto I. Thesis title: Exploring the role of GDF-15 in Cushing’s syndrome: new insights into adrenal steroid dysregulation. Thesis supervisor: Daniele Gianfrilli; External supervisor: Martin Reincke. Final grade: 70/70 with honors. Graduation date: 27/01/2025. -Mar 2024 – Dec 2024: Research project abroad for specialization thesis – University Hospital of Munich (LMU), Department of Internal Medicine IV, Ludwig Maximilian University (LMU), Munich, Germany (Supervisor: Prof. Martin Reincke). -Feb 2019 – Jul 2019: Research scholarship for thesis abroad at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, Oxford (UK), under the supervision of Prof. Jeremy W. Tomlinson. -2013 – 2019: Degree in Medicine and Surgery (MD), Policlinico Umberto I – Sapienza University of Rome. Thesis title: Dose-dependency of adverse metabolic effects in short-term glucocorticoid therapy: a pilot study in healthy volunteers undergoing hyperinsulinemic euglycemic clamp. Supervisor: Prof. Daniele Gianfrilli; External supervisor: Prof. Jeremy W. Tomlinson. Final grade: 110/110 cum laude. Graduation date: 23/09/2019. -2008 – 2013: High School Diploma, G. Marconi Institute – Scientific and Technological High School – Civitavecchia (Rome). Final grade: 100/100. HONORS AND AWARDS -2025: COST Action (CA20122), Short-Term Scientific Missions (4th call) Award. -2024: SIE Rising Star (Italian Society of Endocrinology) for promising young investigators: award recognizing excellence and commitment in the development and execution of the research project during the international research stay at Ludwig Maximilian University, Munich, Germany. -2023: EYES Clinical Observership Program (C.O.P.), European Society of Endocrinology (ESE) Early Career Investigators Exchange Programme at Ludwig Maximilian University, Munich, Germany. -2018: Research scholarship for thesis abroad: award for conducting the medical degree thesis project at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital – Oxford – United Kingdom.

Research products

11573/1761362 - 2026 - Long-term cardiac effects of adrenalectomy versus surveillance in mild cortisol excess: 5-year results from the prospective ITACA study

De Alcubierre, Dario; Ferrari, Davide; Tomaselli, Alessandra; Moscucci, Federica; Bonaventura, Ilaria; Francia, Aurora; Vozza, Elisabetta; Lospinuso, Ilaria; Ettorre, Evaristo; Hasenmajer, Valeria; Minnetti, Marianna; Sbardella, Emilia; Tenuta, Marta; Morelli, Sergio; Paganini, Alessandro M; Isidori, Andrea M; Pofi, Riccardo - 01a Articolo in rivista

paper: EUROPEAN JOURNAL OF ENDOCRINOLOGY (Bristol: Bioscientifica.) pp. 170-184 - issn: 1479-683X - wos: (0) - scopus: 2-s2.0-105029792011 (0)

11573/1742379 - 2025 - Chronotherapy with Once-Daily Osilodrostat Improves Cortisol Rhythm, Quality of Life, and Sleep in Cushing's Syndrome

Ferrari, Davide; Bonaventura, Ilaria; Simeoli, Chiara; Tomaselli, Alessandra; Vincenzi, Ludovica; De Alcubierre, Dario; Sciarra, Francesca; Rizzo, Flavio; Cerroni, Lorenzo; Di Paola, Nicola; Minnetti, Marianna; Sbardella, Emilia; Venneri, Mary Anna; Pofi, Riccardo; Pivonello, Rosario; Gianfrilli, Daniele; Hasenmajer, Valeria; Isidori, Andrea - 01a Articolo in rivista

paper: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (-Springfield, Ill. : Charles C. Thomas -Philadelphia : J.B. Lippincott Co. -Baltimore, Md. : Issued for the Endocrine Society by the Williams & Wilkins Co. -Bethesda, MD : Endocrine Society -Chevy Chase, MD : Endocrine Society) pp. - - issn: 0021-972X - wos: (0) - scopus: (0)

11573/1747097 - 2025 - Gonadal and sexual function in men living with HIV. Insights from a single-centre study

Bonaventura, Ilaria; Hasenmajer, Valeria; D'addario, Nicolò F; Pozza, Carlotta; Ceccarelli, Giancarlo; D'ettorre, Gabriella; Mastroianni, Claudio M; Jannini, Emmanuele A; Gianfrilli, Daniele - 01a Articolo in rivista

paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Sprimger Milano: Kurtis) pp. - - issn: 1720-8386 - wos: WOS:001575795500001 (0) - scopus: 2-s2.0-105017267844 (0)

11573/1750658 - 2025 - Breaking Down Bone Disease in People Living with HIV: Pathophysiology, Diagnosis, and Treatment

Hasenmajer, Valeria; D'addario, Nicolò Francesco; Bonaventura, Ilaria; Sada, Valentina; Nardi, Christopher; Jannini, Emmanuele Angelo; D'ettorre, Gabriella; Mastroianni, Claudio; Gianfrilli, Daniele - 02a Capitolo o Articolo

book: Advances in Experimental Medicine and Biology - (9783031856402; 9783031856419)

11573/1742893 - 2025 - Adrenal causes of endocrine hypertension in childhood or adolescence

Pellegrini, Bianca; Bonaventura, Ilaria; Hasenmajer, Valeria; Simeoli, Chiara; Pivonello, Claudia; Ferrari, Davide; Criscuolo, Sabrina; Tomaselli, Alessandra; Isidori, Andrea M; Grossman, Ashley B; Lenzi, Andrea; De Martino, Maria Cristina; Savage, Martin O - 01g Articolo di rassegna (Review)

paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Sprimger Milano: Kurtis) pp. - - issn: 1720-8386 - wos: WOS:001512295700001 (0) - scopus: 2-s2.0-105008483381 (0)

11573/1755924 - 2025 - Dose-dependent and tissue-specific adverse effects of exogenous glucocorticoids: insights for optimizing clinical practice

Pofi, R.; Othonos, N.; Marjot, T.; Bonaventura, I.; Barrett, A.; White, S.; Miller, H.; Potter, T.; Bailey, M.; Eastell, R.; Gossiel, F.; Woods, C.; Hazlehurst, J. M.; Hodson, L.; Tomlinson, J. W. - 01a Articolo in rivista

paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Springer Milano: Editrice Kurtis Srl) pp. 2067-2076 - issn: 0391-4097 - wos: (0) - scopus: 2-s2.0-105009887877 (2)

11573/1763615 - 2025 - Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study

Nowak, Elisabeth; Zhang, Qilin; Zhang, Shuo; Zhao, Yao; Ye, Hongying; Machado, Márcio Carlos; Moises, Caio Celio Santiago; Tóth, Miklós; Stark, Júlia; Yuen, Kevin C J; Gurnell, Mark; Macfarlane, James; Mccormack, Ann; Govinna, Mauli; Gilis-Januszewska, Aleksandra; Minasyan, Mari; Bonaventura, Ilaria; Czepielewski, Mauro A; Ferriere, Amandine; Gadelha, Monica; Isidori, Andrea M; Kastelan, Darko; Maiter, Dominique; Tabarin, Antoine; Alexandraki, Krystallenia I; Chang, Julia; Frontera, Eric D; Hanzu, Felicia A; Matikainen, Niina; Miljic, Dragana; Pichler, Robert; Popovic, Vera; Spencer-Segal, Joanna L; Tordjman, Karen; Akirov, Amit; Araujo-Castro, Marta; Arvat, Emanuela; Bancos, Irina; Bioletto, Fabio; Burman, Pia; Castinetti, Frederic; Detomas, Mario; Fassnacht, Martin; Feelders, Richard A; Fountas, Athanasios; Igaz, Peter; Ilic, Sasa; Isand, Kristina; Kaltsas, Gregory; Meyer, Gesine; Parasiliti-Caprino, Mirko; Newell-Price, John; Ragnarsson, Oskar; Valassi, Elena; Vila, Greisa; Wass, John; Yoel, Uri; Fleseriu, Maria; Reincke, Martin - 01a Articolo in rivista

paper: THE LANCET DIABETES & ENDOCRINOLOGY () pp. 1030-1040 - issn: 2213-8595 - wos: WOS:001621336000009 (2) - scopus: 2-s2.0-105021707426 (1)

11573/1711296 - 2024 - Exploring sexual function in adrenal insufficiency: findings from the Dual RElease hydrocortisone versus conventionAl glucocorticoid replaceMent therapy in hypocortisolism (DREAM) trial

Hasenmajer, Valeria; De Alcubierre, Dario; Ferrari, Davide; Minnetti, Marianna; Bonaventura, Ilaria; Pofi, Riccardo; Simeoli, Chiara; Tomaselli, Alessandra; Sciarra, Francesca; Bottillo, Grazia; Angelini, Francesco; Cozzolino, Alessia; Venneri, Mary Anna; Jannini, Emmanuele A; Gianfrilli, Daniele; Pivonello, Rosario; Isidori, Andrea M - 01a Articolo in rivista

paper: ANDROLOGY (Oxford: Wiley-Blackwell, 2013-) pp. - - issn: 2047-2927 - wos: WOS:001192132200001 (4) - scopus: 2-s2.0-85189535830 (4)

11573/1704846 - 2024 - Predicting postoperative hypocortisolism in patients with non-aldosterone-producing adrenocortical adenoma: a retrospective single-centre study

Bonaventura, I; Tomaselli, A; Angelini, F; Ferrari, D; De Alcubierre, D; Hasenmajer, V; Sbardella, E; Cozzolino, A; Paganini, A M; Isidori, A M; Minnetti, M; Pofi, R - 01a Articolo in rivista

paper: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (Sprimger Milano: Kurtis) pp. - - issn: 1720-8386 - wos: WOS:001169843200002 (7) - scopus: 2-s2.0-85185469919 (7)

11573/1729115 - 2024 - Circadian clock disruption impairs immune oscillation in chronic endogenous hypercortisolism: a multi-level analysis from a multicentre clinical trial

Hasenmajer, V.; Sbardella, E.; Sciarra, F.; Simeoli, C.; Pivonello, C.; Ceccato, F.; Pofi, R.; Minnetti, M.; Rizzo, F.; Ferrari, D.; Bonaventura, I.; Barbagallo, F.; Giannetta, E.; Alunni Fegatelli, D.; Conia, S.; Navigli, R.; Arnaldi, G.; Scaroni, C.; Pivonello, R.; Gianfrilli, D.; Venneri, M. A.; Isidori, A. M. - 01a Articolo in rivista

paper: EBIOMEDICINE (Amsterdam : Elsevier) pp. - - issn: 2352-3964 - wos: WOS:001415095600001 (12) - scopus: 2-s2.0-85210272739 (13)

11573/1732918 - 2024 - Impact of Female Sex and Mild Cortisol Secretion on Coagulation Profile in Adrenal Incidentalomas

Bonaventura, Ilaria; Minnetti, Marianna; Ferrari, Davide; Hasenmajer, Valeria; Tomaselli, Alessandra; De Alcubierre, Dario; Lenzi, Andrea; Pofi, Riccardo; Isidori, Andrea M - 01a Articolo in rivista

paper: JOURNAL OF THE ENDOCRINE SOCIETY (Washington, DC : Endocrine Society) pp. - - issn: 2472-1972 - wos: WOS:001376680000001 (4) - scopus: 2-s2.0-85216074862 (4)

11573/1755826 - 2023 - Alterazioni della crescita conseguenti a patologie surrenaliche insorte in età pediatrica

Minnetti, Marianna; Bonaventura, Ilaria; Ferrari, Davide; Tomaselli, Alessandra; Hasenmajer, Valeria; Sada, Valentina; Cozzolino, Alessia; Isidori, Andrea M. - 01a Articolo in rivista

paper: L'ENDOCRINOLOGO (Milano: Editrice Kurtis.) pp. - - issn: 1590-170X - wos: (0) - scopus: (0)

11573/1696472 - 2023 - Effects of Dual-Release Hydrocortisone on Bone Metabolism in Primary and Secondary Adrenal Insufficiency: A 6-Year Study

Hasenmajer, Valeria; Ferrari, Davide; De Alcubierre, Dario; Sada, Valentina; Puliani, Giulia; Bonaventura, Ilaria; Minnetti, Marianna; Tomaselli, Alessandra; Pofi, Riccardo; Sbardella, Emilia; Cozzolino, Alessia; Gianfrilli, Daniele; Isidori, Andrea M - 01a Articolo in rivista

paper: JOURNAL OF THE ENDOCRINE SOCIETY (Washington, DC : Endocrine Society) pp. 1-10 - issn: 2472-1972 - wos: WOS:001123949200002 (8) - scopus: (0)

11573/1681988 - 2023 - Extra-Gonadal and Non-Canonical Effects of FSH in Males

Spaziani, Matteo; Carlomagno, Francesco; Tenuta, Marta; Sesti, Franz; Angelini, Francesco; Bonaventura, Ilaria; Ferrari, Davide; Tarantino, Chiara; Fiore, Marco; Petrella, Carla; Tarani, Luigi; Gianfrilli, Daniele; Pozza, Carlotta - 01g Articolo di rassegna (Review)

paper: PHARMACEUTICALS (Basel: MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-13 - issn: 1424-8247 - wos: WOS:001015618400001 (15) - scopus: 2-s2.0-85163877355 (15)

11573/1706842 - 2023 - Assessing treatment adherence is crucial to determine adequacy of mineralocorticoid therapy

Pofi, Riccardo; Bonaventura, Ilaria; Duffy, Joanne; Maunsell, Zoe; Shine, Brian; Isidori, Andrea; W Tomlinson, Jeremy - 01a Articolo in rivista

paper: ENDOCRINE CONNECTIONS (Bristol : BioScientifica) pp. - - issn: 2049-3614 - wos: WOS:001158929600001 (8) - scopus: 2-s2.0-85167703761 (6)

11573/1682997 - 2023 - 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial

Othonos, Nantia; Pofi, Riccardo; Arvaniti, Anastasia; White, Sarah; Bonaventura, Ilaria; Nikolaou, Nikolaos; Moolla, Ahmad; Marjot, Thomas; Stimson, Roland H; Van Beek, André P; Van Faassen, Martijn; Isidori, Andrea M; Bateman, Elizabeth; Sadler, Ross; Karpe, Fredrik; Stewart, Paul M; Webster, Craig; Duffy, Joanne; Eastell, Richard; Gossiel, Fatma; Cornfield, Thomas; Hodson, Leanne; Jane Escott, K; Whittaker, Andrew; Kirik, Ufuk; Coleman, Ruth L; Scott, Charles A B; Milton, Joanne E; Agbaje, Olorunsola; Holman, Rury R; Tomlinson, Jeremy W - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1025- - issn: 2041-1723 - wos: WOS:001050104400005 (30) - scopus: 2-s2.0-85148830348 (32)

11573/1642723 - 2022 - Effects of licorice on sex hormones and the reproductive system

Minnetti, Marianna; De Alcubierre, Dario; Bonaventura, Ilaria; Pofi, Riccardo; Hasenmajer, Valeria; Grazia Tarsitano, Maria; Gianfrilli, Daniele; Poggiogalle, Eleonora; Isidori, Andrea M. - 01g Articolo di rassegna (Review)

paper: NUTRITION (New York, NY : Elsevier Science Incorporated) pp. 111727- - issn: 0899-9007 - wos: WOS:000834281100002 (12) - scopus: 2-s2.0-85134608237 (17)

11573/1556814 - 2021 - Use of contrast enhanced ultrasound in testicular diseases: a comprehensive review

Tenuta, Marta; Sesti, Franz; Bonaventura, Ilaria; Mazzotta, Paola; Pofi, Riccardo; Gianfrilli, Daniele; Pozza, Carlotta - 01g Articolo di rassegna (Review)

paper: ANDROLOGY (Oxford: Wiley-Blackwell, 2013-) pp. - - issn: 2047-2927 - wos: WOS:000660076000001 (14) - scopus: 2-s2.0-85107708225 (15)

11573/1565990 - 2021 - Non-canonical effects of ACTH: insights into adrenal insufficiency

Hasenmajer, Valeria; Bonaventura, Ilaria; Minnetti, Marianna; Sada, Valentina; Sbardella, Emilia; Isidori, Andrea M. - 01g Articolo di rassegna (Review)

paper: FRONTIERS IN ENDOCRINOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-2392 - wos: WOS:000693584600001 (19) - scopus: 2-s2.0-85114319254 (18)

11573/1556810 - 2020 - Co-administration of 5α-reductase inhibitors worsens the adverse metabolic effects of prescribed glucocorticoids

Othonos, Nantia; Marjot, Thomas; Woods, Conor; M Hazlehurst, Jonathan; Nikolaou, Nikolaos; Pofi, Riccardo; White, Sarah; Bonaventura, Ilaria; Webster, Craig; Duffy, Joanne; Cornfield, Thomas; Moolla, Ahmad; Isidori, Andrea; Hodson, Leanne; W Tomlinson, Jeremy - 01a Articolo in rivista