Progress Report Meetings in which 2nd and 3rd year PhD students explain the progress of their research 24 November 2023 Docenti: Giunta (chair), Fatica, Tartaglia, Cacchione, Saggio, Arbitri: Stufera Mecarelli, Amico, Tarullo, Meschino LUDOVICA ALTIERI "CENP-F, a microtubule regulator in mitosis and developing neurons" ALESSANDRO GIAMPIETRO "Characterization of genetic drivers in cancer and aging" 15 December 2023 Docenti: Ciapponi (chair), Dello Ioio, Dimitri, Ballarino, Cruciani Arbitri: Alessandro De Santis, Cazzaniga, Risi, Cappelletto VERONICA FERTITTA "Host-microorganism interactions in obesity and colorectal cancer" CHIARA GRELLONI “Study of circular RNAs role in cancer progression through RNA-RNA interactions” 12 January 2024 Docenti: Raffa (chair), Fanti, Lavia, Presutti, Raimondo Arbitri: Di Cristofano, De Vivo, Menicucci, Lucrezia De Santis ANGELA IUZZOLINO “Exploring the role of alpha-tubulin N-acetyltransferase 1 (ATAT1) in the cancer” VITTORIO PADOVANO “Functional in vivo and in vitro characterisation of lncRNAs in motoneurons in physiological and pathological conditions” 26 January 2024 Docenti: Fatica (chair), Trombetta, Vernì, Bozzoni, Ciapponi, Arbitri: Giampietro, Di Pietro, Tesoriere, Ferreri, ELEONORA PILESI "Relationship between vitamin B6 and cancer in Drosophila melanogaster: the role of DNA damage" LORENZO STUFERA MECARELLI “Study of ALS-related spatial transcriptomic and proteomic alterations in iPSCs-derived motor neurons” 9 February 2024 Docenti: Laneve (chair), Sabatini, Piacentini, Cruciani Arbitri: Iuzzolino, Farrotti, Lepri, Garraffo MARGARYTA SHTIN “Unraveling the molecular circuit governing the Lateral Root Cap Programmed Cell Death events” FEDERICO VINCIARELLI ”Groundbreaking” ability of the root: how to cope with soil’s hardness and avoid obstacles”. 23 February 2024 Docenti: Ciapponi (chair), Guarguaglini, Ballarino, Tartaglia, Serino Arbitri: Pilesi, Gentile, Virginia, Santopietro, Gualdi ALESSANDRO DE SANTIS "The role of non coding RNA in Human Melanoma cells" DEGISEW YINUR MENGISTU "Analysis of the primary microcephaly pathogenic mechanisms using Drosophila as model system" 8 March 2024 Docenti: Dello Ioio (chair), Giunta, Dimitri, Trombetta, Cacchione, Arbitri: Vinciarelli, Grandioso, Medici, Guerrini SAMUELE DI CRISTOFANO “Probing Intermolecular Interactions using Computational Methods” EDISON DI PIETRO “Study of telomeres - From plants to mammals” 22 March 2024 Docenti: Presutti (chair), Fatica, Fanti, Lavia, Raimondo Arbitri: Padovano, Magnanimi, Cannistrà, Piscopo FRANCESCA CAZZANIGA (online) “Improving crop fitness in high salt conditions” ANTONIO VITO AMICO "Study of plant microRNA candidates with possible anti-inflammatory activity: bioinformatic and molecular analyses” 12 April 2024 Docenti: Serino (chair), Serino, Vernì, Saggio, Bozzoni Arbitri: Grelloni, Proietti, Grazzi, Pistacchia MIRKO DE VIVO "Crucial role of Asymmetric Cell Division in plant adaptation to hard and dry soils" SERENA FARROTTI "The air is dry: a quest to safeguard plants from a hotter and drier future". 19 April 2024 Docenti: Cacchione (chair), Laneve, Tartaglia, Piacentini, Cruciani Arbitri: Fertitta, Kazmi, Corda, Silvestri DAVIDE GENTILE "Novel genetic tools to accelerate the breeding of new resilient crop varieties for sustainable agriculture". FRANCESCO MAGNANIMI “Molecular basis of the control of flower opening and closure by essential oils in model and crop plant species" 03 May 2024 Docenti: Guarguaglini (chair), Dello Ioio, Dimitri, Ballarino, Fanti Arbitri: Altieri, Volpe, Vrachnos, Simula ALESSIA GRANDIOSO “Study of synthetic circRNA in therapy” MIRENA PROIETTI “Adaptation to Global change: New insights from Transposable Elements” 17 May 2024 Docenti: Sabatini (chair), Ciapponi, Raffa, Presutti, Vernì Arbitri: Shtin, Biagi, Mastrangelo, Spurio, De Nittis EMILIA VOLPE 'Impact of climate change on human DNA'. KAZMI HIRA “Generation of plants with high germination potential” NOEMI MESCHINO "Detailed investigation into the mosaic embryo karyotypes obtained with preimplantation genetic testing" 31 May 2024 Docenti:Giunta (chair), Bozzoni, Cacchione, Cruciani, Trombetta, Arbitri: Stufera Mecarelli, Amico, Tarullo, Meschino, Barone MARTINA CHIARA BIAGI “Engineering circular RNAs for efficient protein production. FEDERICA CANNISTRA' “Role of the nuclear envelope in physiological and pathological conditions.” MARIA CHIARA CAPPELLETTO "Characterization of epigenetic variations of human Multiple Myeloma: the involvement of NRF1 14 June 2024 Docenti: Dello Ioio, (chair), Dimitri, Fanti, Fatica, Ciapponi, Arbitri: Alessandro De Santis, Cazzaniga, Risi, Cappelletto, Cortile LUCA CORDA "Genetic and epigenetic changes in the repetitive regions of the human genome" ELENA DI TOMMASO "Understanding the role of CENP-A in modulating responses to DNA damage and R-loops formation in human cancers" LUCREZIA DE SANTIS "Dissecting the role LINC00504 and LINC00520 in melanoma phenotype switching" 21 June 2024 Docenti: Ballarino (chair), Guarguaglini, Laneve, Lavia, Piacentini Arbitri: Giampietro, Di Pietro, Menicucci, Lucrezia De Santis, De Nittis ALESSANDRO GRAZZI "CyCoNP lncRNA sustains NCAM1 expression by RNA-RNA direct binding to control human motor neuron specification." ANDREA LEPRI “Unveiling the signaling pathway of light-independent seed germination". ANNA MASTRANGELO “Investigation of the mechanisms regulating AurkA nuclear ocalization” 28 June 2024 Docenti: Presutti(chair), Raffa, Raimondo, Sabatini, Saggio Arbitri:, Di Cristofano, De Vivo, Tesoriere, Ferreri, Gualdo, Piscopo GIULIA MENICUCCI "High resolution NGS approach for non invasive detection of somatic mutations in solid tumors" FLAVIA RISI "Echoes from the last Green Sahara: whole genome analysis of Fulani, a key population to unveil the evolutionary history of Africa" MARCO TARULLO "FTO targeting by chemical inhibition as a strategy against chronic myeloid leukemia" 12 July 2024 Docenti: Serino(chair), Tartaglia, Vernì, Cruciani, Bozzoni Arbitri: Iuzzolino, Farrotti, Lepri, Garraffo, Pistacchia MARGHERITA MEDICI “Targeting the RNA-binding protein HuD (ELAVL4) to control ALS disease" MARIA VIRGINIA SANTOPIETRO "Moonlighting roles of chromatin-remodeling proteins in cell division". GIULIA TESORIERE "Role of Vitamin B6 in cancer using Drosophila as a model system". DIMITRIOS MILTIADIS VRACHNOS “A new theoretical framework to predict phase separation”.