ADVANCES IN CARDIO-THORACIC AND VASCULAR PATHOPHYSIOLOGY AND IMAGING

Call for application 41st cycle

Bando ordinario

Educational goals and objectives

The training objectives concern the training and development of research in the cardiovascular and chest field with the acquisition of notions of ultrasound and advanced radiatrics. The contents of the program are: cardiovascular anatomy and physiology; Vascular, cardiac and chest diseases; non -invasive and invasive diagnostics; notions of medical therapy and advanced surgical therapy methods; vegetative neuroeffectors mechanisms at the cardiovascular level; Identification, lease and biological role of protease inhibitors in the nervous and cardiovascular system; Dopaminergic and cholinergic receptor systems in the cardiovascular system; plasma and tissue protease inhibitors at the level of the cardiovascular system; evaluation of myocardial vitality and transmurality of necrosis after myocardial infarction, through polyparametric techniques; evaluation of the stunned and hibernated myocardium; pulmonary and extra-spy micobacteriasis; Neurotrophic receptors in the lung arteries and in the bronchiol-alveolar washing fluid in sarcoidosis; Aerosolic use of Alfa Interferon in pulmonary tuberculosis and chronic bronchitis; Ethiopathogenesis of pulmonary and extra -polmunary histiocyties.
As far as the imaging area is concerned, the training and development of research will be deepened first of all in the cardio-vascular field, in the oncological and gastro enterological ones through advanced scintigraphy techniques (Spect and Pet). The contents of the program include radiopharmaceuticals for this area, new image techniques, cardiological and gastro-enteric pathophysiology and neoplastic growth. Furthermore, pathophysiology and imaging updates are contemplated through seminars held by Italian and foreign experts in order to create high -level global scientific training in doctorates. The experiences gained will have to lead doctorals to orient themselves in a professional way in the following areas: evaluation of prostheses and vascular endoprotesis. Evaluation of cardiac pathophysiology and relative diagnostic. Evaluation of pneumological pathophysiology and its diagnostics. Diagnostic and therapeutic procedures inherent in Toracic Surgery Pulmonary transplant. Study of Artero-Venose pulmonary fistulas. Study of the artero-venosis cardio-circulators. Applications of scintigraphy in the diagnosis of the pathologies of the cardiovascular and systemic and pulmonary vascular system. Application of computerized tomography (CT) and magnetic resonance imaging (RM) in the diagnosis of the various cardiovascular and chest pathologies. To conclude translational laboratory activities.

Number of positions available

Sapienza Scholarships	Other Scholarships	Departments	Without scholarship
6	3	0	3

Themes, curriculum and specific competence

Borse ENTI TERZI, PARTENARIATI ESTESI, ECCELLENZA

Tematica: Identificazione e targeting dei meccanismi molecolari coinvolti nella radioresistenza nel rabdomiosarcoma pediatrico"
Ente finanziatore: ISTITUTO SUPERIORE DI SANITÀ (ISS)
Competenze richieste: nessuna competenza specifica richiesta

Tematica: scompenso cardiaco.
Ente finanziatore: IRCCS SAN RAFFAELE ROMA S.R.L
Competenze richieste: nessuna competenza specifica richiesta

Admission Procedure

Qualifications assessment	Titles (max 15 points) Titles can be submitted in self-certification. Candidates must send the qualifications electronically when submitting the application. Graduating students at the Master's degree will have a score of 0 under the degree grade. Only candidates who, in the context of the overall evaluation of qualifications and the project, will have achieved minimal score of 30/60

PROJECT EVALUATION	Project (max 45 points) a) title of the research project (max 100 characters); b) research objectives (max 900 characters), first describing the general objective and then identifying the specific objective. In the context of a scientific topic, the general objective of the project ("overall objective" or "goal" in English) consists in the solution of a very general problem and represents a very high goal (which requires a lot of time and / or an approach). multidisciplinary). The specific objective is to solve a specific problem and that is what the candidate undertakes to achieve at the end of the three years. The specific objective, which contributes to the achievement of the general objective, can in turn have sub-objectives, normally it is expressed through a noun and not through a verb (it is the goal, not the path) and must be SMART ( Specific, Measurable, Attainable, Relevant, Time-bound). The results expected during the individual research phases must not be described in this section (see following points); c) state of the art with essential bibliography (max 4,000 characters) which clearly reveals the knowledge of the topics covered and the identification of one or more open problems to which the project intends to respond (with the achievement of the specific objective); d) brief presentation of the various activities planned during the three years of the project (max 5,000 characters); e) time table including all the activities (recruitment, data analysis, thesis processing) foreseen during the three years of the project. For the purposes of the selection, particular attention will be paid to: a) clarity and completeness of the definition and description of the specific objective, the strategy used to achieve it and the time schedule; b) relevance of the project with the educational objectives of the doctorate; c) knowledge of the state of the art and definition of open problems; d) innovative contents of the project; e) feasibility of the project.
language	ITALIANO

Oral interview	Oral exam: max 60 points Candidates who have achieved a minimum assessment of 30/60 (qualifications and project) are admitted to the oral exam. If the number of candidates makes it necessary, the Evaluation Commission will continue the oral test in the days following the one scheduled for the start of the same. During the oral exam the various aspects concerning the proposed project, the CV and the titles presented will be studied in depth. At the same time, there will also be a verification of the knowledge of the English language. The oral exam will only be passed by candidates who have obtained a minimum mark of 30/60. The overall minimum score for inclusion in the final ranking is 60/120.
language	ITALIANO INGLESE

contacts and info

giuliana.fragassi@uniroma1.it

Curriculum studiorum

Graduation date and grade of the Master's degree
detailed list of exams including completion dates and scores of Masters's degree
Graduation date and grade of the Bachelor’s degree
Certificates of participation in post-graduate university courses

Required documentation

§ research project

mandatory
a) title of the research project (max 100 characters);
b) research objectives (max 900 characters), first describing the general objective and then identifying the specific objective. In the context of a scientific topic, the general objective of the project ("overall objective" or "goal" in English) consists in the solution of a very general problem and represents a very high goal (which requires a lot of time and / or an approach). multidisciplinary). The specific objective is to solve a specific problem and that is what the candidate undertakes to achieve at the end of the three years. The specific objective, which contributes to the achievement of the general objective, can in turn have sub-objectives, normally it is expressed through a noun and not through a verb (it is the goal, not the path) and must be SMART ( Specific, Measurable, Attainable, Relevant, Time-bound). The results expected during the individual research phases must not be described in this section (see following points);
c) state of the art with essential bibliography (max 4,000 characters) which clearly reveals the knowledge of the topics covered and the identification of one or more open problems to which the project intends to respond (with the achievement of the specific objective);
d) brief presentation of the various activities planned during the three years of the project (max 5,000 characters);
e) time table including all the activities (recruitment, data analysis, thesis processing) foreseen during the three years of the project.
2.1. For the purposes of the selection, particular attention will be paid to:
a) clarity and completeness of the definition and description of the specific objective, the strategy used to achieve it and the time schedule;
b) relevance of the project with the educational objectives of the doctorate;
c) knowledge of the state of the art and definition of open problems;
d) innovative contents of the project;
e) feasibility of the project.

, the file must be uploaded within le ore 23:59 del 19/06/2025

§ List of publications

optional, the file must be uploaded within le ore 23:59 del 19/06/2025

§ Curriculum Vitae et Studiorum

optional, the file must be uploaded within le ore 23:59 del 19/06/2025

Language Skills

the candidate must know the following languages

ENGLISH

Exam Schedule

Qualifications assessment

day	08/07/2025
notes	none
publication on notice board	NO
publication on the web site	Yes
web site	https://phd.uniroma1.it/web/ADVANCES-IN-CARDIO-THORACIC-AND-VASCULAR-PATHOPHYSIOLOGY-AND-IMAGING_nD4197.aspx
date of publication	11/07/2025
contacts	giuliana.fragassi@unirom11.it

Altra tipologia (PROJECT EVALUATION)

day	08/07/2025
notes	none
time	14:00
classroom	DIREZIONE PRIMA MEDICA
address	viale del policlinico 155
publication on notice board	NO
publication on the web site	Yes
web site	https://phd.uniroma1.it/web/ADVANCES-IN-CARDIO-THORACIC-AND-VASCULAR-PATHOPHYSIOLOGY-AND-IMAGING_nD4197.aspx
date of publication	11/07/2025
contacts	GIULIANA.FRAGASSI@UNIROMA1.IT

Oral interview

day	15/07/2025
notes	none
time	13:00
classroom	aula didattica prima clinica medica secondo piano
address	viale del policlinico 155
publication on notice board	NO
publication on the web site	Yes
web site	(https://phd.uniroma1.it/web/ADVANCES-IN-CARDIO-THORACIC-AND-VASCULAR-PATHOPHYSIOLOGY-AND-IMAGING_nD4197.aspx):
date of publication	15/07/2025
contacts	giuliana.fragassi@unirom11.it

Evaluation scale

Qualifications assessment

Valutazione titoli

Punteggio massimo complessivo per la prova/overall max score: 15

SPECIALIZZAZIONE
SPECIALIZATION

Punteggio massimo/max score: 2

70 E LODE 70 E LODE	2,0
70 70	1,0
<70 <70	0,0

VOTO DI LAUREA
THESIS EVALUATION

Punteggio massimo/max score: 3

VOTO DI LAUREA SPECIALISTICA
Degree mark

110 e lode 10 cum laude	3,0
110 110	2,0
105 -109 105-109	1,0
<105 e candidati laureandi alla laurea magistrale <105 and candidates undergraduated	0,0

PUBBLICAZIONI
PUBBLICATIONS

Punteggio massimo/max score: 10

6 ARTICOLI 6 ARTICLERS	6,0
5 ARTICOLI 5 ARTICLES	5,0
4 ARTICOLI 4 ARTICLES	4,0
3 ARTICOLI 3 ARTICLES	3,0
2 ARTICOLI 2 ARTICLES	2,0
1 ARTICOLO 1 ARTICLES	1,0
candidato ultimo o primo autore in 1 pubblicazion FIRST OR LAST AUTHOR IN 1 ARTICLE	2,0
candidato ultimo o primo autore in 2 pubblicazioni FIRST OR LAST AUTHOR IN 2 ARTICLES	3,0
candidato ultimo o primo autore in più di 2 pubblicazione FIRST OR LAST AUTHOR IN MORE THAN 2 ARTICLES	4,0

Altra tipologia (PROJECT EVALUATION)

Altra tipologia

VALUTAZIONE DEL PROGETTO
PROJECT EVALUATION

Punteggio massimo complessivo per la prova/overall max score: 45

VALUTAZIONE PROGETTO
PROJECT EVALUATION

Punteggio massimo/max score: 45

Oral interview

Prova orale

Punteggio massimo complessivo per la prova/overall max score: 60

PROVA ORALE
ORAL EVALUATION

Punteggio massimo/max score: 60