CARLOTTA ZEPPILLI

Dottoressa di ricerca

ciclo: XXXV


supervisore: Dott. Antonio Profico, Dott.ssa Ileana Micarelli
co-supervisore: Prof. Giorgio Manzi

Titolo della tesi: Geometric Morphometrics and Functional Morphology applied to the study of skeletal remains from archaeological and modern samples

Bones are living tissue and can be considered an archive that records and stores an individual's biological and cultural data, providing direct evidence of the biology of past populations. Factors that occur and influence bones’ structure during the lifetime can be mechanical (e.g., activity levels and patterns) and non-mechanical (e.g., biological factors). Over the years, numerous methods have been proposed for reconstructing physical activities and mobility through the analysis of long bones diaphyseal morphology. Notably, analyses of the lower limb allow to observe the influence of lifestyle and mobility patterns, while the study of the upper limb aims to examine the presence of lateralisation (i.e., a preference for using one side over the other). This project aims to study cortical bone thickness and distribution in the diaphyses of femurs, tibiae, and humeri in a virtual environment. The sample under examination comprises CT scans of: i) recently deceased modern individuals selected from the forensic New Mexico Decedent Image Database: for each individual biological information and loading history are reported (e.g., occupations and physical activities); ii) archaeological skeletal remains from Classical and Early Medieval Italian cemeteries (Lucus Feroniae, RM; Povegliano Veronese; VR Selvicciola, VT), with a further application of the method proposed for some palaeopathological case studies from the same sites. The combined use of known modern and archaeological individuals offers the opportunity to consider, as comprehensively as possible, the study of variability within the sample, taking into account a broader range of factors. A new R package, morphomap, was applied and implemented. This approach aims not to limit the investigation to a few sections along the diaphysis but allow a detailed analysis of cortical bone distribution, thickness, and morphology along the entire diaphysis. The study is therefore potentially able to achieve a high degree of detail. Each cross-section is then analysed using an integrated approach that combines Cross-Sectional Geometry and Geometric Morphometrics, followed by multivariate statistics. The results of the explorative analyses are promising: the known modern sample allowed us to investigate which biological factors (specifically sex and age) most influence the morphology and thickness of cortical bone in the humeri, femurs, and tibiae. In particular, an interesting correlation was found within the age-specific women's sample, suggesting a possible occurrence of osteoporosis, but further analyses are needed to better explore this result. Finally, the application of this approach to some palaeopathological case studies was presented. For each case, a multidisciplinary investigation was applied allowing to reconstruct the individual's osteobiography. This thesis takes advantage of a known sample and an innovative technique. Its principal outcome is that the multidisciplinary approach overcomes data availability limitations and broadens possible interpretations. These results provide an efficient tool for future research in different disciplines, such as human evolution, primatology, and archaeology.

Produzione scientifica

  • 11573/1672353 - 2022 - Living and surviving in the Roman Empire: skeletal trauma and strontium isotopes of an individual from Lucus Feroniae (Rome, Italy) (04d Abstract in atti di convegno)
    FARESE, MARTINA; FORMICHELLA, GIULIA; BERNARDINI, SARA; ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; MANZI, GIORGIO; TAFURI, MARY ANNE
  • 11573/1571027 - 2021 - Morphometric maps of bilateral asymmetry in the human humerus. An implementation in the R package morphomap (01a Articolo in rivista)
    PROFICO, ANTONIO; ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; RAIA, PASQUALE; MANZI, GIORGIO
  • 11573/1678568 - 2023 - Stabbed to death. An osteobiography example of violence among Longobards (Povegliano Veronese, Italy, 6th-8th c CE) (01a Articolo in rivista)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; BERNARDINI, SARA; PROFICO, ANTONIO; DI GIANNANTONIO, STEFANIA; GIOSTRA, CATERINA; MANZI, GIORGIO; TAFURI, MARY ANNE
  • 11573/1562808 - 2021 - Abnormal development of paired enigmatic structures in the derived dicynodont Lystrosaurus murrayi (Therapsida, Anomodontia) (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA
  • 11573/1199996 - 2018 - CA-LSE and AST-3D: two new digital tools for reproducing the inner cavities of skeletal elements (04d Abstract in atti di convegno)
    BUZI, COSTANTINO; PROFICO, ANTONIO; VENEZIANO, ALESSIO; ZEPPILLI, CARLOTTA; MANZI, GIORGIO
  • 11573/1657564 - 2022 - An integrated approach to the study of long bone morphology and cortical thickness distribution (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; PROFICO, ANTONIO; MICARELLI, ILEANA; MANZI, GIORGIO
  • 11573/1575209 - 2021 - Stabbed by a blade during the barbarian invasions: the case of multiple perimortem traumas from an Italian Longobard cemetery (6th-8th c. CE) (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; TAFURI, MARY ANNE; MANZI, GIORGIO
  • 11573/1491322 - 2020 - Quantifying the lateralization in the upper limb of historical human populations: a detailed study of the cortical bone distribution in the humeral diaphysis (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; PROFICO, ANTONIO; TAFURI, MARY ANNE; MANZI, GIORGIO
  • 11573/1657567 - 2022 - Health care among an Early Medieval community in Italy (Selvicciola, 4th-8th centuries CE) (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; BERNARDINI, SARA; PROFICO, ANTONIO; TAFURI, MARY ANNE; MANZI, GIORGIO
  • 11573/1657565 - 2022 - Severe ankylosis of the left hip in the Early Medieval Community of Selvicciola (Italy, 4th-8th Centuries CE) (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; BERNARDINI, SARA; PROFICO, ANTONIO; TAFURI, MARY ANNE; MANZI, GIORGIO
  • 11573/1671641 - 2023 - Multi-isotope analysis of primary and secondary dentin as a mean to broaden intra-life dietary reconstruction. A case from Longobard Italy (01a Articolo in rivista)
    BERNARDINI, SARA; ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; MANZI, GIORGIO; TAFURI, MARY ANNE
  • 11573/1571067 - 2021 - Measuring the asymmetry in long bone morphometric maps of cortical thickness: occupationrelated differences in the modern human humerus (04d Abstract in atti di convegno)
    ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; MANZI, GIORGIO
  • 11573/1672358 - 2022 - Were they actually local? Strontium isotope analysis of individuals from the Roman cemetery of Lucus Feroniae (Rome, Italy) (04f Poster)
    FARESE, MARTINA; BERNARDINI, SARA; ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; MANZI, GIORGIO; TAFURI, MARY ANNE
  • 11573/1672361 - 2022 - Indagini paleopatologiche e isotopiche su uno scheletro femminile di epoca romana imperiale (Lucus Feroniae, I-III secolo CE) (04f Poster)
    FARESE, MARTINA; FORMICHELLA, GIULIA; BERNARDINI, SARA; ZEPPILLI, CARLOTTA; MICARELLI, ILEANA; MANZI, GIORGIO; TAFURI, MARY ANNE

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