VALERIO LICURSI

email: valerio.licursi@uniroma1.it
phone:

PRESENT POSITION
Full time Researcher
Institute of Biology and Molecular Pathology (IBPM-CNR), National Research Council of Italy (CNR)
c/o Dept. of Biology and Biotechnology “C. Darwin”, "Sapienza" University of Rome

EDUCATION
2023 ASN Associate Professor, 05/E2 – SSD BIO/11 Molecular Biology
2011 Ph.D. in Cell and Developmental Biology, Sapienza University of Rome, Italy. Research activity: Transcriptome and proteome analysis in superior cervical ganglion of dystrophic mdx mice
2007 Master’s Degree in Genomic Biotechnology with 110/110 cum laude, Sapienza University of Rome, Italy

PREVIOUS RESEARCH POSITIONS
2019-2022: Researcher (RTDA) at the Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome.
2016-2018: Post-Doc position at the Institute for Systems Analysis and Computer Science “Antonio Ruberti”, National Research Council, EPIGEN project. Research activity: Development of computational models for functional genomics applied to the study of tumors.
May 2015-Aug 2016: Post-Doc position at the Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome. Research activity: Dissecting the role of potential inhibitor drug of histone H3 lysine 4 demethylases using genome-wide approaches.
Jan 2011-Sep 2014: Post-Doc position at the Dept. of Biology and Biotechnology “C. Darwin”, Sapienza University of Rome.

RESEARCH FUNDING PROJECTS
In the last 10 years, scientific collaborations have been developed and maintained with several Italian and International groups.
2023-2025: Unit PI, PRIN 2022: “Nr2f1-dependent regulation of Mitochondrial Function in Neural Development and Disease”
2023-2025: Unit PI, PRIN 2022 PNRR: “The role of miR-211 in neuronal aging: From Disease Mechanisms to Therapy”
2020-2022: Member of the project founded by Regione Lazio: “Progetto Genoma Trisomia 21 (HGP-T21)”
2019-2022: Member of the project founded by ASI: "MARS-PRE: MARcatori biologici e funzionali per la biomedicina”
2019-2021: PI, project founded by Sapienza University of Rome: “Role of the chromatin remodeller histone demethylase KDM5B and its isoforms in breast cancer and melanoma”
2016: PI, project founded by Sapienza University of Rome. Title of the project: “The Cop9 Signalosome Complex as a therapeutic target in human cancer”
2011-2013: Member of the project PRIN: “Ruolo dei Fattori Regolativi Generali (GRF) di S. cerevisiae nell’organizzazione strutturale e dinamica della cromatina”

ACADEMIC AND SCIENTIFIC SUPERVISION
Scientific Supervisor of 1 Ph.D. student. I was Tutor of 2 Ph.D. students and more than 10 M.Sc. and B.Sc. students belonging to the Bioinformatics, Biotechnology and Genetic and Molecular Biology courses of the Sapienza University of Rome.

REVIEWER ACTIVITIES
Reviewer for the international journals “Plos One” ISSN 1932-6203, “DATABASE” ISSN 1758-0463

TEACHING ACTIVITIES
2019-present: Holder of the course: "Bioinformatics I" (6 CFU). Degree in "Bioinformatics". Sapienza University of Rome.
2019-2021: Practical training for the course “Statistics for Biologists”, Scuola di Dottorato in Biologia e Medicina Molecolare (BEMM)", Sapienza University of Rome
2014-2018: Practical training in statistics with R for the course “Statistica”, Scuola di Dottorato in Biologia e Medicina Molecolare (BEMM)", Sapienza University of Rome
2012-2014: Lessons and practical training in Microarray data analysis using R/Bioconductor during Trascrittomica course of the postgraduate Master’s course: "Bioinformatica: applicazioni biomediche e farmaceutiche", Sapienza University of Rome.

BIBLIOMETRIC INDEXES
ORCID ID: 0000-0002-8172-1437
Total number of publications: 49
Citations: 820
h-index: 17
Source: Scopus

PUBLICATIONS OF THE LAST TEN YEARS
1. Giuliani A, Licursi V, Nisi PS, et al. Dbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors. Stem Cell Rev and Rep. Published online August 22, 2023. doi:10.1007/s12015-023-10600-7
2. Fragale A, Stellacci E, Romagnoli G, et al. Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects. Int J Cancer. 2023;153(5):1080-1095. doi:10.1002/ijc.34602
3. Di Nisio E, Licursi V, Mannironi C, et al. A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression. Cancer Gene Ther. Published online January 26, 2023. doi:10.1038/s41417-022-00584-w
4. Di Nisio E, Danovska S, Condemi L, et al. H3 Lysine 4 Methylation Is Required for Full Activation of Genes Involved in α-Ketoglutarate Availability in the Nucleus of Yeast Cells after Diauxic Shift. Metabolites. 2023;13(4):507. doi:10.3390/metabo13040507
5. Wang W, Di Nisio E, Licursi V, et al. Simulated Microgravity Modulates Focal Adhesion Gene Expression in Human Neural Stem Progenitor Cells. Life. 2022;12(11):1827. doi:10.3390/life12111827
6. Tiberti S, Catozzi C, Croci O, et al. GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome. Nat Commun. 2022;13:6752. doi:10.1038/s41467-022-34467-3
7. Sibilio P, Belardinilli F, Licursi V, Paci P, Giannini G. An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy. Biology Direct. 2022;17(1):10. doi:10.1186/s13062-022-00324-y
8. Gualtieri A, Bianconi V, Renzini A, Pieroni L, Licursi V, Mozzetta C. The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth. Cell Reports. 2022;40(9):111267. doi:10.1016/j.celrep.2022.111267
9. Mandolesi G, Rizzo FR, Balletta S, et al. The microRNA let-7b-5p Is Negatively Associated with Inflammation and Disease Severity in Multiple Sclerosis. Cells. 2021;10(2). doi:10.3390/cells10020330
10. Mancini M, Grasso M, Muccillo L, et al. DNMT3A epigenetically regulates key microRNAs involved in epithelial-to-mesenchymal transition in prostate cancer. Carcinogenesis. 2021;(bgab101). doi:10.1093/carcin/bgab101
11. Licursi V, Wang W, Di Nisio E, et al. Transcriptional modulations induced by proton irradiation in mice skin in function of adsorbed dose and distance. Journal of Radiation Research and Applied Sciences. 2021;14(1):260-270. doi:10.1080/16878507.2021.1949675
12. Etna MP, Severa M, Licursi V, et al. Genome-Wide Gene Expression Analysis of Mtb-Infected DC Highlights the Rapamycin-Driven Modulation of Regulatory Cytokines via the mTOR/GSK-3β Axis. Frontiers in Immunology. 2021;12. Accessed July 24, 2023. https://www.frontiersin.org/articles/10.3389/fimmu.2021.649475
13. Di Nisio E, Lupo G, Licursi V, Negri R. The Role of Histone Lysine Methylation in the Response of Mammalian Cells to Ionizing Radiation. Frontiers in Genetics. 2021;12. Accessed July 24, 2023. https://www.frontiersin.org/articles/10.3389/fgene.2021.639602
14. Di Giulio S, Colicchia V, Pastorino F, et al. A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors. Oncogene. Published online September 10, 2021:1-10. doi:10.1038/s41388-021-02003-0
15. Dentici ML, Alesi V, Quinodoz M, et al. Biallelic variants in ZNF526 cause a severe neurodevelopmental disorder with microcephaly, bilateral cataract, epilepsy and simplified gyration. J Med Genet. Published online January 4, 2021. doi:10.1136/jmedgenet-2020-107430
16. De Vito F, Musella A, Fresegna D, et al. MiR-142-3p regulates synaptopathy-driven disease progression in multiple sclerosis. Neuropathol Appl Neurobiol. Published online September 7, 2021. doi:10.1111/nan.12765
17. Salvi E, Rutten JP, Di Mambro R, et al. A Self-Organized PLT/Auxin/ARR-B Network Controls the Dynamics of Root Zonation Development in Arabidopsis thaliana. Developmental Cell. 2020;53(4):431-443.e23. doi:10.1016/j.devcel.2020.04.004
18. Paci P, Fiscon G, Conte F, et al. Integrated transcriptomic correlation network analysis identifies COPD molecular determinants. Sci Rep. 2020;10:3361. doi:10.1038/s41598-020-60228-7
19. Licursi V, Anzellotti S, Favaro J, et al. X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics. Sci Rep. 2020;10:6562. doi:10.1038/s41598-020-63348-2
20. Gasparini S, Licursi V, Presutti C, Mannironi C. The Secret Garden of Neuronal circRNAs. Cells. 2020;9(8):1815. doi:10.3390/cells9081815
21. Gasparini S, Del Vecchio G, Gioiosa S, et al. Differential Expression of Hippocampal Circular RNAs in the BTBR Mouse Model for Autism Spectrum Disorder. Mol Neurobiol. 2020;57(5):2301-2313. doi:10.1007/s12035-020-01878-6
22. Coni S, Serrao SM, Yurtsever ZN, et al. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation. Cell Death Dis. 2020;11(12):1045. doi:10.1038/s41419-020-03174-6
23. Antonelli F, Esposito A, Calvo L, et al. Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing. PLoS ONE. 2020;15(1):e0227639. doi:10.1371/journal.pone.0227639
24. Rossi MN, Pascarella A, Licursi V, et al. NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial Cells. Front Cell Dev Biol. 2019;7. doi:10.3389/fcell.2019.00252
25. Pontiggia D, Spinelli F, Fabbri C, et al. Changes in the microsomal proteome of tomato fruit during ripening. Sci Rep. 2019;9. doi:10.1038/s41598-019-50575-5
26. Pippa S, Mannironi C, Licursi V, et al. Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B. Molecules. 2019;24(9). doi:10.3390/molecules24091739
27. Morciano P, Di Giorgio ML, Porrazzo A, et al. Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells. Front Physiol. 2019;10. doi:10.3389/fphys.2019.00383
28. Mocavini I, Pippa S, Licursi V, et al. JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer. Cancer Sci. 2019;110(4):1232-1243. doi:10.1111/cas.13925
29. Luly FR, Lévêque M, Licursi V, et al. MiR-146a is over-expressed and controls IL-6 production in cystic fibrosis macrophages. Sci Rep. 2019;9(1):16259. doi:10.1038/s41598-019-52770-w
30. Licursi V, Conte F, Fiscon G, Paci P. MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis. BMC Bioinformatics. 2019;20(1). doi:10.1186/s12859-019-3105-x
31. Conte F, Fiscon G, Licursi V, et al. A paradigm shift in medicine: A comprehensive review of network-based approaches. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. Published online August 2, 2019:194416. doi:10.1016/j.bbagrm.2019.194416
32. Fiscon G, Conte F, Licursi V, Nasi S, Paci P. Computational identification of specific genes for glioblastoma stem-like cells identity. Scientific Reports. 2018;8(1):7769. doi:10.1038/s41598-018-26081-5
33. Licursi V, Cestelli Guidi M, Del Vecchio G, et al. Leptin induction following irradiation is a conserved feature in mammalian epithelial cells and tissues. Int J Radiat Biol. 2017;93(9):947-957. doi:10.1080/09553002.2017.1339918
34. Guadagno NA, Moriconi C, Licursi V, et al. Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB. Neurobiol Dis. 2017;103:32-44. doi:10.1016/j.nbd.2017.03.010
35. Fragale A, Romagnoli G, Licursi V, et al. Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells. Cancer Immunol Res. 2017;5(7):604-616. doi:10.1158/2326-6066.CIR-17-0080
36. Carucci N, Cacci E, Nisi PS, et al. Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis. R Soc Open Sci. 2017;4(4):160913. doi:10.1098/rsos.160913
37. Capitano F, Camon J, Licursi V, et al. MicroRNA-335-5p modulates spatial memory and hippocampal synaptic plasticity. Neurobiol Learn Mem. 2017;139:63-68. doi:10.1016/j.nlm.2016.12.019
38. Capitano F, Camon J, Ferretti V, et al. microRNAs Modulate Spatial Memory in the Hippocampus and in the Ventral Striatum in a Region-Specific Manner. Mol Neurobiol. 2016;53(7):4618-4630. doi:10.1007/s12035-015-9398-5
39. Piersanti S, Burla R, Licursi V, et al. Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups. PLOS ONE. 2015;10(7):e0133607. doi:10.1371/journal.pone.0133607
40. Simão D, Pinto C, Piersanti S, et al. Modeling Human Neural Functionality In Vitro: Three-Dimensional Culture for Dopaminergic Differentiation. Tissue Engineering Part A. 2014;21(3-4):654-668. doi:10.1089/ten.tea.2014.0079
41. Licursi V, Salvi C, De Cesare V, et al. The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae. The FEBS Journal. 2014;281(1):175-190. doi:10.1111/febs.12584
42. Guidi MC, Mirri C, Fratini E, Licursi V, Marcelli A. FT-IR imaging spectroscopy as a complementary analytical technique to monitor lipids as biomarkers to high-LET (linear energy transfer) radiation. Rend Fis Acc Lincei. 2014;25(1):75-79. doi:10.1007/s12210-013-0273-x
43. Giusti N, Bufalieri F, Licursi V, et al. General features of the transcriptional response of mammalian cells to low- and high-LET irradiation. Rendiconti Lincei. 2014;25(S1):69-74. doi:10.1007/s12210-013-0274-9
44. Piersanti S, Astrologo L, Licursi V, et al. Differentiated neuroprogenitor cells incubated with human or canine adenovirus, or lentiviral vectors have distinct transcriptome profiles. PLoS ONE. 2013;8(7):e69808. doi:10.1371/journal.pone.0069808

Research products

11573/1742644 - 2025 - The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

#, Ilenia Masi; #, Flavia Ottavi; Caprara, Valentina; Del Rio, Danila; Kunkl, Martina; Spadaro, Francesca; Licursi, Valerio; Tuosto, Loretta; Bagnato, Anna; Rosano., Laura - 01a Articolo in rivista

paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: (0) - scopus: (0)

11573/1731944 - 2025 - The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration

Cencioni, Chiara; Malatesta, Silvia; Vigiano Benedetti, Virginia; Licursi, Valerio; Perfetto, Livia; Conte, Federica; Ranieri, Danilo; Bartolazzi, Armando; Kunkl, Martina; Tuosto, Loretta; Larghi, Alberto; Piro, Geny; Agostini, Antonio; Tortora, Giampaolo; Corbo, Vincenzo; Carbone, Carmine; Spallotta, Francesco - 01a Articolo in rivista

paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001399492200001 (14) - scopus: 2-s2.0-85216439800 (15)

11573/1742845 - 2025 - NSD2 and miRNAs as key regulators of melanoma response to Romidepsin and Interferon‐α2b treatment

De Santis, Alessandro; De Santis, Lucrezia; Rossi, Francesca; Gasparini, Silvia; Licursi, Valerio; Amico, Vito Antonio; Capone, Imerio; Fragale, Alessandra; D'atri, Stefania; De Lucia, Gabriele; Presutti, Carlo - 01a Articolo in rivista

paper: CANCER MEDICINE ([Chichester]: John Wiley & Sons Ltd Oxford : Blackwell Publishing) pp. - - issn: 2045-7634 - wos: WOS:001490931600001 (1) - scopus: 2-s2.0-105005581674 (1)

11573/1748123 - 2025 - Transcriptomic analysis reveals an estradiol-responsive pathway in Arabidopsis involving EDS1 and RBOHD and its modulation upon B. cinerea infection

Di Renzo, Sara; Guerrisi, Laura; Licursi, Valerio; De Lorenzo, Giulia - 04f Poster

conference: XIV National Congress of the Italian Society of Plant Biology (Palermo; Italy)

book: Abstract book XIV Congress of the Italian Society of Plant Biology - ()

11573/1752644 - 2025 - Analysis of microRNA-transcript regulatory networks in the hippocampus of the BTBR mouse model of autism

Gasparini, Silvia; Licursi, Valerio; Rinaldi, Arianna; Ricceri, Laura; Scattoni, Maria Luisa; Presutti, Carlo; Mannironi, Cecilia - 01a Articolo in rivista

paper: FRONTIERS IN CELLULAR NEUROSCIENCE (Lausanne (PO Box 110, 1015) : Frontiers Research Foundation, 2007-) pp. - - issn: 1662-5102 - wos: (0) - scopus: (0)

11573/1734833 - 2025 - The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

Masi, I.; Ottavi, F.; Caprara, V.; Rio, D. D.; Kunkl, M.; Spadaro, F.; Licursi, V.; Tuosto, L.; Bagnato, A.; Rosano', L. - 01a Articolo in rivista

paper: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:001427668200001 (4) - scopus: 2-s2.0-85218488658 (4)

11573/1737313 - 2025 - An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

Paldino, G.; Tedeschi, V.; Progano, V.; Salvati, E.; Licursi, V.; Vertecchi, E.; Bivolaru, A. L.; Molteni, E.; Scrivo, R.; Congia, M.; Cauli, A.; Caccavale, R.; Paroli, M.; Kunkl, M.; Tuosto, L.; Sorrentino, R.; Fiorillo, M. T. - 01a Articolo in rivista

paper: ARTHRITIS & RHEUMATOLOGY (Malden, MA : John Wiley & Sons, [2014]-) pp. 1-13 - issn: 2326-5205 - wos: WOS:001423251000001 (4) - scopus: 2-s2.0-85219691456 (4)

11573/1741577 - 2025 - Cxcr3 promotes protection from colorectal cancer liver metastasis by driving NK cell infiltration and plasticity

Russo, Eleonora; D'aquino, Chiara; Di Censo, Chiara; Laffranchi, Mattia; Tomaipitinca, Luana; Licursi, Valerio; Garofalo, Stefano; Promeuschel, Johann; Peruzzi, Giovanna; Sozio, Francesca; Kaffke, Anna; Garlanda, Cecilia; Panzer, Ulf; Limatola, Cristina; Vosshenrich, Christian A. J.; Sozzani, Silvano; Sciume', Giuseppe; Santoni, Angela; Bernardini, Giovanni - 01a Articolo in rivista

paper: THE JOURNAL OF CLINICAL INVESTIGATION (New York, N.Y. : American Society for Clinical Investigation, 1924-) pp. - - issn: 1558-8238 - wos: (0) - scopus: 2-s2.0-105007749324 (12)

11573/1746695 - 2025 - TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation

Tucci, Gloria; Pacella, Ilenia; Pinzon Grimaldos, Alessandra; Rossi, Alessandra; Cammarata, Ilenia; Zagaglioni, Marta; Peruzzi, Giovanna; Tirelli, Valentina; Sanchez, Massimo; Pietropaolo, Giuseppe; Sozio, Francesca; Del Prete, Annalisa; Licursi, Valerio; Barnaba, Vincenzo; Piconese, Silvia - 01a Articolo in rivista

paper: EUROPEAN JOURNAL OF IMMUNOLOGY (Weinheim : Wiley-VCH-Verl.) pp. - - issn: 1521-4141 - wos: WOS:001587241900013 (1) - scopus: 2-s2.0-105016768348 (1)

11573/1726179 - 2024 - Dissecting the role of LINC00504 and LINC00520 in melanoma phenotype switching

De Santis, Lucrezia; Licursi, Valerio; De Santis, Alessandro; Amico, Vito Antonio; Presutti, Carlo - 04f Poster

conference: RNA Therapeutics: From Concept to Clinic (Worcester, Massachusetts, USA)

book: RNA Therapeutics: From Concept to Clinic Abstracts - ()

11573/1714348 - 2024 - To Erase or Not to Erase: Non-Canonical Catalytic Functions and Non-Catalytic Functions of Members of Histone Lysine Demethylase Families

Di Nisio, Elena; Manzini, Valeria; Licursi, Valerio; Negri, Rodolfo - 01g Articolo di rassegna (Review)

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-21 - issn: 1422-0067 - wos: (0) - scopus: (0)

11573/1726831 - 2024 - Imaging-based methods to identify prognostic and predictive biomarkers for Hereditary Spastic Paraplegia

Fattorini, G.; Licursi, V.; Santorelli, M. F.; Silvestri, G.; Casali, C.; Rinaldo, C.; Sardina, F. - 04f Poster

conference: European Microscopy Conference 2024 (Copenhagen, DK)

book: EMC24 conference - ()

11573/1726832 - 2024 - Development of cell imaging-tools to identify prognostic and predictive biomarkers in Hereditary Spastic Paraplegia (HSP)

Fattorini, Gaia; Licursi, V.; Santorelli, M. F.; Silvestri, Gabriella; Casali, C.; Rinaldo, Cinzia; Sardina, F. - 04f Poster

conference: National PhD Meeting - ABCD (Bologna (BO), Italy)

book: ABCD PhD symposium - 2024 - ()

11573/1725880 - 2024 - The role of lysine histone demethylase KDM5B isoform on cellular migration and transcription regulation in breast cancer

Manzini, Valeria; Di Nisio, Elena; Tosto, Marta; Piana, Alessandro; Mannironi, Cecilia; Negri, Rodolfo; Licursi, Valerio - 04f Poster

conference: ABCD National Ph.D. Meeting (Bologna)

book: National Ph.D. Meeting Abstracts - ()

11573/1714626 - 2024 - Iron capture through CD71 drives perinatal and tumor-associated Treg expansion

Pacella, Ilenia; Pinzon Grimaldos, Alessandra; Rossi, Alessandra; Tucci, Gloria; Zagaglioni, Marta; Potenza, Elena; Pinna, Valeria; Rotella, Ivano; Cammarata, Ilenia; Cancila, Valeria; Belmonte, Beatrice; Tripodo, Claudio; Pietropaolo, Giuseppe; Di Censo, Chiara; Sciume', Giuseppe; Licursi, Valerio; Peruzzi, Giovanna; Antonucci, Ylenia; Campello, Silvia; Guerrieri, Francesca; Iebba, Valerio; Prota, Rita; Di Chiara, Maria; Terrin, Gianluca; De Peppo, Valerio; Grazi, Gian Luca; Barnaba, Vincenzo; Piconese, Silvia - 01a Articolo in rivista

paper: JCI INSIGHT (Ann Arbor, Michigan : American Society for Clinical Investigation, [2016]-) pp. - - issn: 2379-3708 - wos: WOS:001292821400001 (8) - scopus: 2-s2.0-85201029837 (8)

11573/1725857 - 2024 - Staphylococcus aureus colonizing the skin microbiota of adults with severe atopic dermatitis exhibits genomic diversity and convergence in biofilm traits

Sivori, Francesca; Cavallo, Ilaria; Truglio, Mauro; De Maio, Flavio; Sanguinetti, Maurizio; Fabrizio, Giorgia; Licursi, Valerio; Francalancia, Massimo; Fraticelli, Fulvia; La Greca, Ilenia; Lucantoni, Federica; Camera, Emanuela; Mariano, Maria; Ascenzioni, Fiorentina; Cristaudo, Antonio; Pimpinelli, Fulvia; Di Domenico, Enea Gino - 01a Articolo in rivista

paper: BIOFILM (Amsterdam: Elsevier B.V.) pp. - - issn: 2590-2075 - wos: WOS:001325238500001 (9) - scopus: 2-s2.0-85204725610 (9)

11573/1678489 - 2023 - H3 Lysine 4 Methylation Is Required for Full Activation of Genes Involved in α-Ketoglutarate Availability in the Nucleus of Yeast Cells after Diauxic Shift

Di Nisio, Elena; Danovska, Svetlana; Condemi, Livia; Cirigliano, Angela; Rinaldi, Teresa; Licursi, Valerio; Negri, Rodolfo - 01a Articolo in rivista

paper: METABOLITES (Basel : MDPI) pp. - - issn: 2218-1989 - wos: WOS:000977144100001 (1) - scopus: 2-s2.0-85153740514 (1)

11573/1667930 - 2023 - A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression

Di Nisio, Elena; Licursi, Valerio; Mannironi, Cecilia; Buglioni, Valentina; Paiardini, Alessandro; Robusti, Giulia; Noberini, Roberta; Bonaldi, Tiziana; Negri, Rodolfo - 01a Articolo in rivista

paper: CANCER GENE THERAPY (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. - - issn: 0929-1903 - wos: WOS:000918402800001 (8) - scopus: 2-s2.0-85146853977 (8)

11573/1693674 - 2023 - Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects

Fragale, Alessandra; Stellacci, Emilia; Romagnoli, Giulia; Licursi, Valerio; Parlato, Stefania; Canini, Irene; Remedi, Giacomo; Buoncervello, Maria; Matarrese, Paola; Pedace, Lucia; Ascione, Barbara; Pizzi, Simone; Tartaglia, Marco; D'atri, Stefania; Presutti, Carlo; Capone, Imerio; De Lucia, Gabriele - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF CANCER (New York, NY : Wiley-Liss) pp. 1080-1095 - issn: 1097-0215 - wos: WOS:001007348400001 (4) - scopus: 2-s2.0-85161647992 (4)

11573/1687377 - 2023 - Dbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors

Giuliani, A.; Licursi, V.; Nisi, P. S.; Fiore, M.; D'angelo, S.; Biagioni, S.; Negri, R.; Rugg-Gunn, P. J.; Cacci, E.; Lupo, G. - 01a Articolo in rivista

paper: STEM CELL REVIEWS AND REPORTS (New York NY: Springer; New York NY: Humana Press) pp. - - issn: 2629-3277 - wos: WOS:001052536000001 (1) - scopus: 2-s2.0-85168462377 (0)

11573/1677241 - 2022 - The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth

Gualtieri, Alberto; Bianconi, Valeria; Renzini, Alessandra; Pieroni, Luisa; Licursi, Valerio; Mozzetta, Chiara - 01a Articolo in rivista

paper: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. - - issn: 2211-1247 - wos: WOS:000875166100001 (10) - scopus: 2-s2.0-85137058763 (10)

11573/1638208 - 2022 - An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

Sibilio, P.; Belardinilli, F.; Licursi, V.; Paci, P.; Giannini, G. - 01a Articolo in rivista

paper: BIOLOGY DIRECT (London: BioMed Central) pp. 10- - issn: 1745-6150 - wos: WOS:000792626600001 (7) - scopus: 2-s2.0-85129491391 (8)

11573/1660646 - 2022 - GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

Tiberti, S.; Catozzi, C.; Croci, O.; Ballerini, M.; Cagnina, D.; Soriani, C.; Scirgolea, C.; Gong, Z.; He, J.; Macandog, A. D.; Nabinejad, A.; Nava Lauson, C. B.; Quinte', A.; Bertalot, G.; Petz, W. L.; Ravenda, S. P.; Licursi, V.; Paci, P.; Rasponi, M.; Rotta, L.; Fazio, N.; Ren, G.; Fumagalli-Romario, U.; Schaefer, M. H.; Campaner, S.; Lugli, E.; Nezi, L.; Manzo, T. - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. - - issn: 2041-1723 - wos: WOS:000885370100005 (57) - scopus: 2-s2.0-85141565395 (54)

11573/1660151 - 2022 - Simulated microgravity modulates focal adhesion gene expression in human neural stem progenitor cells

Wang, Wei; Di Nisio, Elena; Licursi, Valerio; Cacci, Emanuele; Lupo, Giuseppe; Kokaia, Zaal; Galanti, Sergio; Degan, Paolo; D'angelo, Sara; Castagnola, Patrizio; Tavella, Sara; Negri, Rodolfo - 01a Articolo in rivista

paper: LIFE (Basel: MDPI) pp. - - issn: 2075-1729 - wos: WOS:000884128000001 (3) - scopus: 2-s2.0-85141693372 (2)

11573/1568587 - 2021 - An Overview of the computational models dealing with the regulatory ceRNA mechanism and ceRNA deregulation in cancer

Conte, F.; Fiscon, G.; Sibilio, P.; Licursi, V.; Paci, P. - 02a Capitolo o Articolo

book: Methods in Molecular Biology - (978-1-0716-1502-7; 978-1-0716-1503-4)

11573/1568488 - 2021 - MiR-142-3p regulates synaptopathy-driven disease progression in multiple sclerosis

De Vito, Francesca; Musella, Alessandra; Fresegna, Diego; Rizzo, Francesca Romana; Gentile, Antonietta; Bassi, Mario Stampanoni; Gilio, Luana; Buttari, Fabio; Procaccini, Claudio; Colamatteo, Alessandra; Bullitta, Silvia; Guadalupi, Livia; Caioli, Silvia; Vanni, Valentina; Balletta, Sara; Sanna, Krizia; Bruno, Antonio; Dolcetti, Ettore; Furlan, Roberto; Finardi, Annamaria; Licursi, Valerio; Drulovic, Jelena; Pekmezovic, Tatjana; Fusco, Clorinda; Bruzzaniti, Sara; Hornstein, Eran; Uccelli, Antonio; Salvetti, Marco; Matarese, Giuseppe; Centonze, Diego; Mandolesi, Georgia - 01a Articolo in rivista

paper: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. - - issn: 0305-1846 - wos: WOS:000703989100001 (24) - scopus: 2-s2.0-85116392858 (27)

11573/1528841 - 2021 - Biallelic variants in ZNF526 cause a severe neurodevelopmental disorder with microcephaly, bilateral cataract, epilepsy and simplified gyration

Dentici, M. L.; Alesi, V.; Quinodoz, M.; Robens, B.; Guerin, A.; Lebon, S.; Poduri, A.; Travaglini, L.; Graziola, F.; Afenjar, A.; Keren, B.; Licursi, V.; Capuano, A.; Dallapiccola, B.; Superti-Furga, A.; Novelli, A. - 01a Articolo in rivista

paper: JOURNAL OF MEDICAL GENETICS (BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 1-8 - issn: 0022-2593 - wos: WOS:000722666900001 (8) - scopus: 2-s2.0-85098989323 (9)

11573/1569898 - 2021 - A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors

Di Giulio, Stefano; Colicchia, Valeria; Pastorino, Fabio; Pedretti, Flaminia; Fabretti, Francesca; Nicolis Di Robilant, Vittoria; Ramponi, Valentina; Scafetta, Giorgia; Moretti, Marta; Licursi, Valerio; Belardinilli, Francesca; Peruzzi, Giovanna; Infante, Paola; Goffredo, Bianca Maria; Coppa, Anna; Canettieri, Gianluca; Bartolazzi, Armando; Ponzoni, Mirco; Giannini, Giuseppe; Petroni, Marialaura - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000694774500002 (30) - scopus: 2-s2.0-85118235580 (32)

11573/1538086 - 2021 - The role of histone lysine methylation in the response of mammalian cells to Ionizing radiation

Di Nisio, Elena; Lupo, Giuseppe; Licursi, Valerio; Negri, Rodolfo - 01a Articolo in rivista

paper: FRONTIERS IN GENETICS (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-8021 - wos: WOS:000639426900001 (28) - scopus: 2-s2.0-85104034704 (30)

11573/1550695 - 2021 - Genome-Wide Gene Expression Analysis of Mtb-Infected DC Highlights the Rapamycin-Driven Modulation of Regulatory Cytokines via the mTOR/GSK-3β Axis

Etna, M. P.; Severa, M.; Licursi, V.; Pardini, M.; Cruciani, M.; Rizzo, F.; Giacomini, E.; Macchia, G.; Palumbo, O.; Stallone, R.; Carella, M.; Livingstone, M.; Negri, R.; Pellegrini, S.; Coccia, E. M. - 01a Articolo in rivista

paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-16 - issn: 1664-3224 - wos: WOS:000645669000001 (8) - scopus: 2-s2.0-85105228964 (8)

11573/1588017 - 2021 - Transcriptional modulations induced by proton irradiation in mice skin in function of adsorbed dose and distance

Licursi, Valerio; Wang, Wei; Di Nisio, Elena; Cammarata, Francesco P.; Acquaviva, Rosaria; Russo, Giorgio; Manti, Lorenzo; Cestelli Guidi, Mariangela; Fratini, Emiliano; Kamel, Gihan; Amendola, Roberto; Pisciotta, Pietro; Negri, Rodolfo - 01a Articolo in rivista

paper: JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES (Cairo: Egyptian Society of Radiation Sciences and Applications) pp. 260-270 - issn: 1687-8507 - wos: WOS:000687850800001 (2) - scopus: (0)

11573/1501737 - 2021 - The microRNA let-7b-5p Is negatively associated with Inflammation and disease severity in multiple sclerosis

Mandolesi, Georgia; Rizzo, Francesca Romana; Balletta, Sara; Stampanoni Bassi, Mario; Gilio, Luana; Guadalupi, Livia; Nencini, Monica; Moscatelli, Alessandro; Ryan, Colleen Patricia; Licursi, Valerio; Dolcetti, Ettore; Musella, Alessandra; Gentile, Antonietta; Fresegna, Diego; Bullitta, Silvia; Caioli, Silvia; Vanni, Valentina; Sanna, Krizia; Bruno, Antonio; Buttari, Fabio; Castelli, Chiara; Presutti, Carlo; De Santa, Francesca; Finardi, Annamaria; Furlan, Roberto; Centonze, Diego; De Vito, Francesca - 01a Articolo in rivista

paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000622404600001 (29) - scopus: 2-s2.0-85101385576 (29)

11573/1471575 - 2020 - Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation

Coni, S.; Serrao, S. M.; Yurtsever, Z. N.; Di Magno, L.; Bordone, R.; Bertani, C.; Licursi, V.; Ianniello, Z.; Infante, P.; Moretti, M.; Petroni, M.; Guerrieri, F.; Fatica, A.; Macone, A.; De Smaele, E.; Di Marcotullio, L.; Giannini, G.; Maroder, M.; Agostinelli, E.; Canettieri, G. - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (London: Nature Group-Springer London: Nature Publishing Group, 2001-) pp. - - issn: 2041-4889 - wos: WOS:000597627300001 (60) - scopus: 2-s2.0-85097416564 (62)

11573/1329897 - 2020 - A paradigm shift in medicine: a comprehensive review of network-based approaches

Conte, F.; Fiscon, G.; Licursi, V.; Bizzarri, D.; D'anto, T.; Farina, L.; Paci, P. - 01g Articolo di rassegna (Review)

paper: BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS (Amsterdam-UK : Elsevier) pp. - - issn: 1874-9399 - wos: WOS:000528165200002 (63) - scopus: 2-s2.0-85070199010 (75)

11573/1438971 - 2020 - The Secret Garden of Neuronal circRNAs

Gasparini, S.; Licursi, V.; Presutti, C.; Mannironi, C. - 01g Articolo di rassegna (Review)

paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000567163700001 (13) - scopus: 2-s2.0-85089131257 (13)

11573/1371754 - 2020 - Differential Expression of Hippocampal Circular RNAs in the BTBR Mouse Model for Autism Spectrum Disorder

Gasparini, S; Del Vecchio, G; Gioiosa, S; Flati, T; Castrignano, T; Legnini, I; Licursi, V; Ricceri, L; Scattoni, Ml; Rinaldi, A; Presutti, C; Mannironi, C - 01a Articolo in rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. - - issn: 0893-7648 - wos: WOS:000511046000001 (19) - scopus: 2-s2.0-85079457292 (19)

11573/1383443 - 2020 - X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics

Licursi, Valerio; Anzellotti, Silvia; Favaro, Jessica; Sineri, Serena; Carucci, Nicoletta; Cundari, Enrico; Fiore, Mario; Guarguaglini, Giulia; Pippa, Simone; Nisi, Paola S.; Verni', Fiammetta; Biagioni, Stefano; Cacci, Emanuele; Amendola, Roberto; Lupo, Giuseppe; Negri, Rodolfo - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000562147700003 (7) - scopus: 2-s2.0-85083477391 (8)

11573/1365548 - 2020 - Integrated transcriptomic correlation network analysis identifies COPD molecular determinants

Paci, Paola; Fiscon, Giulia; Conte, Federica; Licursi, Valerio; Morrow, Jarrett; Hersh, Craig; Cho, Michael; Castaldi, Peter; Glass, Kimberly; Silverman, Edwin K.; Farina, Lorenzo - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000551092600001 (35) - scopus: 2-s2.0-85085713157 (38)

11573/1460624 - 2020 - A Self-Organized PLT/Auxin/ARR-B Network Controls the Dynamics of Root Zonation Development in Arabidopsis thaliana

Salvi, E.; Rutten, J. P.; Di Mambro, R.; Polverari, L.; Licursi, V.; Negri, R.; Dello Ioio, R.; Sabatini, S.; Ten Tusscher, K. - 01a Articolo in rivista

paper: DEVELOPMENTAL CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 431-443.e23 - issn: 1534-5807 - wos: WOS:000534591500009 (77) - scopus: 2-s2.0-85084386730 (77)

11573/1330755 - 2019 - MIENTURNET: An interactive web tool for microRNA-target enrichment and network-based analysis

Licursi, V.; Conte, F.; Fiscon, G.; Paci, P. - 01a Articolo in rivista

paper: BMC BIOINFORMATICS ([London]: BioMed Central, [2000]-) pp. 545- - issn: 1471-2105 - wos: WOS:000494652100001 (293) - scopus: 2-s2.0-85074548656 (307)

11573/1329470 - 2019 - MiR-146a is over-expressed and controls IL-6 production in cystic fibrosis macrophages

Luly, Francesco Renato; Leveque, M.; Licursi, V.; Cimino, G.; Martin-Chouly, C.; Theret, N.; Negri, R.; Cavinato, L.; Ascenzioni, F.; Del Porto, P. - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000494945700026 (46) - scopus: 2-s2.0-85074711373 (42)

11573/1219880 - 2019 - JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer

Mocavini, Ivano; Pippa, Simone; Licursi, Valerio; Paci, Paola; Trisciuoglio, Daniela; Mannironi, Cecilia; Presutti, Carlo; Negri, Rodolfo - 01a Articolo in rivista

paper: CANCER SCIENCE (Tokyo : Japanese Cancer Association) pp. 1232-1243 - issn: 1349-7006 - wos: WOS:000467640800010 (28) - scopus: 2-s2.0-85063872530 (28)

11573/1247880 - 2019 - Depletion of ATP-citrate lyase (ATPCL) affects chromosome integrity without altering histone acetylation in Drosophila mitotic cells

Morciano, Patrizia; Di Giorgio, Maria Laura; Porrazzo, Antonella; Licursi, Valerio; Negri, Rodolfo; Yikang, Rong; Cenci, Giovanni - 01a Articolo in rivista

paper: FRONTIERS IN PHYSIOLOGY (Lausanne: Frontiers Research Foundation, 2010-) pp. 1-5 - issn: 1664-042X - wos: WOS:000463418100001 (7) - scopus: 2-s2.0-85068225424 (6)

11573/1266997 - 2019 - Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b

Pippa, S; Mannironi, C; Licursi, V; Bombardi, Luca; Colotti, G; Cundari, E; Mollica, A; Coluccia, A; Naccarato, V; La Regina, G; Silvestri, R; Negri, R - 01a Articolo in rivista

paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000469518100098 (26) - scopus: 2-s2.0-85065652898 (27)

11573/1319743 - 2019 - Changes in the microsomal proteome of tomato fruit during ripening

Pontiggia, Daniela; Spinelli, Francesco; Fabbri, Claudia; Licursi, Valerio; Negri, Rodolfo; De Lorenzo, Giulia; Mattei, Benedetta - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000489011300012 (17) - scopus: 2-s2.0-85072940146 (22)

11573/1330816 - 2019 - NLRP2 Regulates Proinflammatory and Antiapoptotic Responses in Proximal Tubular Epithelial Cells

Rossi, M. N.; Pascarella, A.; Licursi, V.; Caiello, I.; Taranta, A.; Rega, L. R.; Levtchenko, E.; Emma, F.; De Benedetti, F.; Prencipe, G. - 01a Articolo in rivista

paper: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. - - issn: 2296-634X - wos: WOS:000495417000001 (40) - scopus: 2-s2.0-85074658329 (40)

11573/1287522 - 2018 - Computational identification of specific genes for glioblastoma stem-like cells identity

Fiscon, G.; Conte, F.; Licursi, V.; Nasi, S.; Paci, P. - 01a Articolo in rivista

paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 1-10 - issn: 2045-2322 - wos: WOS:000432339200001 (42) - scopus: 2-s2.0-85047239443 (44)

11573/929601 - 2017 - MicroRNA-335-5p modulates spatial memory and hippocampal synaptic plasticity

Capitano, F.; Camon, J.; Licursi, V.; Ferretti, V.; Maggi, L.; Scianni, M.; Del Vecchio, G.; Rinaldi, A.; Mannironi, C.; Limatola, C.; Presutti, C.; Mele, A. - 01a Articolo in rivista

paper: NEUROBIOLOGY OF LEARNING AND MEMORY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 63-68 - issn: 1074-7427 - wos: WOS:000396386200008 (31) - scopus: 2-s2.0-85008331029 (34)

11573/950767 - 2017 - Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis

Carucci, Nicoletta; Cacci, Emanuele; Nisi, Paola Serena; Licursi, Valerio; Paul, Yu Lee; Biagioni, Stefano; Negri, Rodolfo; Rugg Gunn, Peter J.; Lupo, Giuseppe - 01a Articolo in rivista

paper: ROYAL SOCIETY OPEN SCIENCE (London : The Royal Society) pp. - - issn: 2054-5703 - wos: WOS:000400527200011 (7) - scopus: 2-s2.0-85017271064 (7)

11573/1013437 - 2017 - Antitumor effects of epidrug/IFN alpha combination driven by modulated gene signatures in both colorectal cancer and dendritic cells

Fragale, Alessandra; Romagnoli, Giulia; Licursi, Valerio; Buoncervello, Maria; Del Vecchio, Giorgia; Giuliani, Caterina; Parlato, Stefania; Leone, Celeste; De Angelis, Marta; Canini, Irene; Toschi, Elena; Belardelli, Filippo; Negri, Rodolfo; Capone, Imerio; Presutti, Carlo; Gabriele, Lucia - 01a Articolo in rivista

paper: CANCER IMMUNOLOGY RESEARCH (American Association for Cancer Research, Inc. (AACR), 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404; Phone: (215) 440-9300 or Toll Free: (866) 423-3965; Fax: (215) 446-7289; E-mail: cancerimmunolres@aacr.org.) pp. 604-616 - issn: 2326-6066 - wos: WOS:000404725300009 (28) - scopus: 2-s2.0-85022069828 (30)

11573/950793 - 2017 - Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB

Guadagno, Noemi Antonella; Moriconi, Claudia; Licursi, Valerio; D'acunto, Emanuela; Nisi, Paola Serena; Carucci, Nicoletta; De Jaco, Antonella; Cacci, Emanuele; Negri, Rodolfo; Lupo, Giuseppe; Miranda Banos, Maria Elena - 01a Articolo in rivista

paper: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 32-44 - issn: 0969-9961 - wos: WOS:000401683200004 (25) - scopus: 2-s2.0-85016948857 (26)

11573/1013439 - 2017 - Leptin induction following irradiation is a conserved feature in mammalian epithelial cells and tissues

Licursi, Valerio; Cestelli Guidi, Mariangela; Del Vecchio, Giorgia; Mannironi, Cecilia; Presutti, Carlo; Amendola, Roberto; Negri, Rodolfo - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 947-957 - issn: 0955-3002 - wos: WOS:000408781700008 (5) - scopus: 2-s2.0-85022176113 (4)

11573/828074 - 2016 - microRNAs Modulate Spatial Memory in the Hippocampus and in the Ventral Striatum in a Region-Specific Manner

Capitano, Fabrizio; Camon, Jeremy; Ferretti, Valentina; Licursi, Valerio; De Vito, Francesca; Rinaldi, Arianna; Vincenti, Sara; Mannironi, C.; Fragapane, P.; Bozzoni, Irene; Oliverio, Alberto; Negri, Rodolfo; Presutti, Carlo; Mele, Andrea - 01a Articolo in rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 4618-4630 - issn: 0893-7648 - wos: WOS:000380678600029 (15) - scopus: 2-s2.0-84940195325 (17)

11573/933277 - 2016 - Methylome profiling of BRCA-positive and BRCA-negative MBCs

Rizzolo, Piera; Silvestri, Valentina; Licursi, Valerio; Navazio, Anna Sara; Valentini, Virginia; Zelli, Veronica; Bianchi, S.; Palli, D.; Fox, S.; Ottini, Laura - 04d Abstract in atti di convegno

paper: EUROPEAN JOURNAL OF CANCER (Oxford, UK: Elsevier Science Limited Oxford; New York: Pergamon, 1990-.) pp. S18-S19 - issn: 0959-8049 - wos: WOS:000431649800054 (0) - scopus: (0)

11573/850648 - 2015 - S.cerevisiae as a tool to select inhibitors of the deneddylating activity of the COP9 signalome Angela Cirigliano, Sergio Menta, Mattia Mori, Valerio Licursi, Svetlana Danovska, Valentina Vapore, Giovanna Serino, Elah Pick, Bruno Botta, Rodolfo Negri, and Teresa Rinaldi

Cirigliano, Angela; Menta, Sergio; Mori, Mattia; Licursi, Valerio; Danovska, Svetlana; Vapore, Valentina; Serino, Giovanna; Pick, Elah; Botta, Bruno; Negri, Rodolfo; Rinaldi, Teresa - 04f Poster

conference: 27° International Congres of Yeast genetics and Molecular Biology (Levico Terme (Italia)

11573/854568 - 2015 - Poster: "In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation”

Danovska, Svetlana; Cundari, Enrico; Mannironi, Cecilia; Licursi, Valerio; Rinaldi, Teresa; Fabozzi, Simone; Cerini, Valentina; Proietto, Marco; Pippa, Simone; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 04a Atto di comunicazione a congresso

conference: ICYGMB - Internationa Congress of Yeast Genetics and Molecular Biology (Levico Terme (TN))

book: Abstracts of the 27th International Conference on Yeast Genetics and Molecular Biology - ()

11573/825138 - 2015 - Transcriptional response of human neurospheres to helper-dependent CAV-2 vectors involves the modulation of DNA damage response, microtubule and centromere gene groups

Piersanti, Stefania; Burla, Romina; Licursi, Valerio; Brito, Catarina; La Torre, Mattia; Alves, Paula M.; Simao, Daniel; Mottini, Carla; Salinas, Sara; Negri, Rodolfo; Tagliafico, Enrico; Kremer, Eric J.; Saggio, Isabella - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e0133607- - issn: 1932-6203 - wos: WOS:000358622000110 (10) - scopus: 2-s2.0-84941710940 (11)

11573/816085 - 2015 - Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation

Simão, Daniel; Pinto, Catarina; Piersanti, Stefania; Weston, Anne; Peddie, Christopher J; Bastos, André E. P; Licursi, Valerio; Schwarz, Sigrid C; Collinson, Lucy M; Salinas, Sara; Serra, Margarida; Teixeira, Ana P; Saggio, Isabella; Lima, Pedro A; Kremer, Eric J; Schiavo, Giampietro; Brito, Catarina; Alves, Paula M. - 01a Articolo in rivista

paper: TISSUE ENGINEERING. PARTS A, B AND C (New Rochelle, NY : Mary Ann Liebert, Inc.) pp. 654-668 - issn: 2152-4947 - wos: WOS:000349611600024 (33) - scopus: 2-s2.0-84923296267 (38)

11573/624801 - 2014 - In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation

Danovska, S.; Pippa, S.; Licursi, V.; Mannironi, C.; Vapore, Valentina; Proietto, Marco; Bufalieri, F.; Cundari, E.; Alagia, A.; Rinaldi, Teresa; Famiglini, V.; Coluccia, A.; La Regina, Giuseppe; Silvestri, R.; Negri, Rodolfo - 04b Atto di convegno in volume

conference: XIII FISV Congress (Pisa, PI, Italy)

book: Program and Abstracts XIII FISV Congress - (978-88-6741-223-5)

11573/553284 - 2014 - A proposed integrated systems approach to the radiation biology of cosmic interest: biophysics and molecular characterization of tissues irradiated with 14 MeV neutrons

Licursi, Valerio; Emiliano, Fratini; Barbara, Benassi; Mariangela Cestelli, Guidi; Claudia, Consales; Augusto, Marcelli; Chiara, Mirri; Negri, Rodolfo; Roberto, Amendola - 01a Articolo in rivista

paper: RENDICONTI LINCEI. SCIENZE FISICHE E NATURALI (Milano : Springer Verlag Italia) pp. s23-s27 - issn: 2037-4631 - wos: WOS:000332688700007 (1) - scopus: 2-s2.0-84899442680 (1)

11573/527777 - 2014 - The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae

Licursi, Valerio; Salvi, Chiara; Virginia De, Cesare; Rinaldi, Teresa; Mattei, Maria Benedetta; Fabbri, Claudia; Serino, Giovanna; Laylan, Bramasole; Jacob Z., Zimbler; Elah, Pick; Brett M., Barnes; Martin, Bard; Negri, Rodolfo - 01a Articolo in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 175-190 - issn: 1742-464X - wos: WOS:000330591100014 (17) - scopus: 2-s2.0-84891830764 (16)

11573/553282 - 2014 - General features of the transcriptional response of mammalian cells to low- and high-LET irradiation

Nicoletta, Giusti; Bufalieri, Francesca; Licursi, Valerio; Tiziana, Castrignano'; Mattia, D'antonio; Roberto, Amendola; Negri, Rodolfo - 01a Articolo in rivista

paper: RENDICONTI LINCEI. SCIENZE FISICHE E NATURALI (Milano : Springer Verlag Italia) pp. S69-S74 - issn: 2037-4631 - wos: WOS:000332688700014 (2) - scopus: 2-s2.0-84899425792 (1)

11573/623792 - 2014 - High Throughput Comparative Analysis of the Response of Human and Nonhuman Primate Neurons To Viral Vectors

Stefania, Piersanti; Licursi, Valerio; Catarina, Brito; Burla, Romina; Alves, Paula; Daniel, Simao; Gina, Devau; Mottini, Carla; Negri, Rodolfo; Enrico, Tagliafico; Kremer, Eric J.; Saggio, Isabella - 04c Atto di convegno in rivista

paper: MOLECULAR THERAPY (San Diego, CA : Academic Press, 2000-) pp. S192-S192 - issn: 1525-0024 - wos: WOS:000337231300494 (0) - scopus: (0)

conference: 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT) (Washington, DC)

11573/517839 - 2013 - Differentiated Neuroprogenitor Cells Incubated with Human or Canine Adenovirus, or Lentiviral Vectors Have Distinct Transcriptome Profiles

Piersanti, Stefania; Astrologo, Letizia; Licursi, Valerio; Costa, Rossella; Enrica, Roncaglia; Aurelie, Gennetier; Sandy, Ibanes; Miguel, Chillon; Negri, Rodolfo; Enrico, Tagliafico; Eric J., Kremer; Saggio, Isabella - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e69808-e69808 - issn: 1932-6203 - wos: WOS:000322838900086 (16) - scopus: 2-s2.0-84880796476 (15)

11573/505124 - 2012 - The transcriptional response of mammalian cancer cells to irradiation is dominated by a cell cycle signature which is strongly attenuated in non-cancer cells and tissues

Bufalieri, Francesca; Licursi, Valerio; Mattia, D'antonio; Tiziana, Castrignano; Roberto, Amendola; Negri, Rodolfo - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 822-829 - issn: 0955-3002 - wos: WOS:000310536700004 (6) - scopus: 2-s2.0-84868338871 (5)

11573/766202 - 2012 - A role for jhd2 demethylase in transcription regulation in S.cerevisiae

C., Mannironi; Danovska, Svetlana; F., Crebelli; A., Peserico; Alagia, Angela Alessandra; Rinaldi, Teresa; Licursi, Valerio; Proietto, Marco; E., Cundari; Negri, Rodolfo - 04a Atto di comunicazione a congresso

conference: XII FISV congress (Rome, Italy)

11573/434051 - 2012 - Lack of dystrophin in mdx mice modulates the expression of genes involved in neuron survival and differentiation

Licursi, Valerio; I., Caiello; Lombardi, Loredana; De Stefano, Maria Egle; Negri, Rodolfo; Paggi, Paola - 01a Articolo in rivista

paper: EUROPEAN JOURNAL OF NEUROSCIENCE (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 691-701 - issn: 0953-816X - wos: WOS:000301119000006 (9) - scopus: 2-s2.0-84858001120 (10)

11573/481156 - 2012 - In vivo skin leptin modulation after 14 MeV neutron irradiation: a molecular and FT-IR spectroscopic study

M., Cestelli Guidi; C., Mirri; E., Fratini; Licursi, Valerio; Negri, Rodolfo; A., Marcelli; R., Amendola - 01a Articolo in rivista

paper: ANALYTICAL AND BIOANALYTICAL CHEMISTRY (Heidelberg: Springer) pp. 1317-1326 - issn: 1618-2642 - wos: WOS:000307957800007 (45) - scopus: 2-s2.0-84865529557 (44)

11573/623984 - 2012 - A role for Jhd2 de-methylase in transcription regulation in S.cerevisiae

Mannironi, C.; Danovska, S.; Crebelli, F.; Peserico, A.; Alagia, A. A.; Rinaldi, Teresa; Licursi, V.; Proietto, Marco; Cundari, E.; Negri, Rodolfo - 04d Abstract in atti di convegno

conference: XII FISV Congress (Roma)

11573/540577 - 2012 - Canine adenovirus (CAV-2) vectors induce an innate immune response and a modulation of cell cycle genes in dopaminergic differentiated human midbrain neuronal progenitors.

Piersanti, S.; Astrologo, L.; Licursi, V.; Negri, R.; Roncaglia, E.; Tagliafico, E.; Schwarz, S.; Schwarz, J.; Kremer, E. J.; Saggio, I.; Negri, Rodolfo - 04f Poster

conference: FISV 2012, 12th Congress (Roma, Italia)

11573/540606 - 2012 - Canine adenovirus (CAV-2) vectors induce an innate immune response and a modulation of cell cycle genes in human dopaminergic neurons.

Piersanti, S.; Astrologo, L.; Licursi, V.; Negri, R.; Roncaglia, E.; Tagliafico, E.; Schwarz, S.; Schwarz, J.; Kremer, E. J.; Saggio, I.; Negri, Rodolfo - 04f Poster

conference: 10th International Adenovirus Meeting (Umeå, Svezia)

11573/526271 - 2012 - Canine adenovirus (CAV-2) vectors induce an innate immune response and the modulation of cell cycle genes in dopaminergic differentiated human midbrain neuronal precursors

Piersanti, Stefania; Astrologo, Letizia; Licursi, V.; Negri, Rodolfo; Roncaglia, E.; Tagliafico, E.; Kremer, E. J.; Saggio, Isabella - 04c Atto di convegno in rivista

paper: HUMAN GENE THERAPY (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. A157-A157 - issn: 1043-0342 - wos: WOS:000310364400473 (0) - scopus: (0)

conference: Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy/French-Society-of-Cell-and-Gene-Therapy (Versailles, FRANCE)

11573/763191 - 2012 - Role of the CSN5 subunit of Cop9 signalosome in transcription modulation of genes involved in zinc and lipid metabolism in S. cerevisiae

Salvi, Chiara; Licursi, Valerio; Alagia, Angela Alessandra; De Cesare, Virginia; Mattei, Maria Benedetta; Rinaldi, Teresa; Serino, Giovanna; G., Balliano; E., Pick; B. M., Barnes; M., Bard; Negri, Rodolfo - 04a Atto di comunicazione a congresso

conference: 12th FISV Congress (Rome, Italy)

book: 12th FISV Congress Federazione Italiana Scienze della Vita - ()

11573/530101 - 2011 - Role of the COP9 signalosome in transcription modulation of genes involved in lipid metabolism and ergosterol biosynthesis in S.cerevisiae

De Cesare, Virginia; V., Di Maria; Salvi, Chiara; Licursi, Valerio; Rinaldi, Teresa; Serino, Giovanna; G., Balliano; Negri, Rodolfo - 04c Atto di convegno in rivista

paper: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 83-83 - issn: 1742-464X - wos: WOS:000292333101032 (1) - scopus: (0)

conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/354502 - 2011 - Dose-Dependent Onset of Regenerative Program in Neutron Irradiated Mouse Skin

Emiliano, Fratini; Licursi, Valerio; Mara, Artibani; Katarzyna, Kobos; Paolo, Colautti; Negri, Rodolfo; Roberto, Amendola - 01a Articolo in rivista

paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e19242 -1-e19242 -12 - issn: 1932-6203 - wos: WOS:000290019400040 (14) - scopus: 2-s2.0-79955726634 (14)