Phd in NETWORK ONCOLOGY AND PRECISION MEDICINE

email: umberto.malapelle@unina.it
phone: +39 0817463674
building: 20
room: 8

Curriculum vitae

Umberto Malapelle, Ph.D.
Researcher in Anatomic Pathology,
Department of Public Health,
University of Naples “Federico II”,
via S. Pansini 5, 80131, Naples, Italy

Contact information
Date and Place of birth: 17/04/1985; Naples.
Business address: Department of Public Health, University of Naples “Federico II”, via S. Pansini 5, 80131, Naples, Italy.
Cell: + 39 3203850702.
E- mail: umberto.malapelle@unina.it
Foreign Languages: Italian (mother tongue)
English (good reading, spoken and written)
Spanish (good reading, spoken and written)

Education
2009: Medical Biotechnology Degree, summa cum laude, University of Naples “Federico II”, Naples, Italy.
2013: Ph.D. in Anatomic Pathology, “Title of Thesis: “Valutazione dello stato mutazionale degli oncogeni predittivi di risposta terapeutica al trattamento di EGFR: validazione analitica e clinica.”, University of Naples “Federico II”, Naples, Italy.

Licensure:
AA_074980, Naples. (from 24/02/2016)

National Academic Qualification as Associate Professor from 29/04/2019 to 29/04/2025 (art. 16, comma 1, law 240/10)

Member of the Scientific Comminssion, School of medicine, University of Naples “Federico II“ (D.R. n. 3422 of 26/10/2020)

Professional Experience
2008: Research Partnership Italy-Spain. Molecular Pathology Laboratory (Prof. M. A. Piris) Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain.
2010: Training in “Laser capture microdissection with PALM MicroBeamsystem (Zeiss), Molecular Diagnostics Unit (Prof. Luis Lombardia), Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain.
2013: Ion PGM Training at Life Technologies in Frankfurter Str. 129B, 64293 Darmstadt, Germany.
2015 - 2017 Research Partnership Molecular Predictive Pathology, Pangaea Inst/Dexeus University, Barcelona, Spain.

National and International Research Projects
• 2008-2010: Research group member, Italy-Spain Partnership (MIUR grant, IT1816). Role of akt kinase in growth control of haematological and solid neoplasms. In collaboration with Dr. Miguel Angel Piris del Programa de Patologia Molecular Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.
• 2009-2012: Project PRIN Member: Histological and immunohistochemical effects of combined administration of rapamycin, tolvaptan, and AEZ-131 on the progression of polycystic disease in PCK rats, University of Naples “Federico II”, Naples, Italy.
• 2015-present: Co-Investigator Research Project “Molecular Biology in indeterminate thyroid FNA” funded by Regione Campania (Legge Regionale n. 24 del 29/12/2005).
• 2016-present: Co-Investigator Research Project ”Traslation in clinical practice of ctDNA analysis for EGFR mutation in NSCLC patients” Promoter: University of Naples “Federico II”, Naples, Italy.


Academic Appointments:
• 2013 - present: Speaker at the theoretical-practical Master's degree in “Metodologie di Anatomia Patologica per lo studio dei biomarcatori predittivi di risposta terapeutica” (coordinator prof. Giancarlo troncone), Department of Publich Health, University of Naples “Federico II”.
• 2016 – present: Professor for teaching activities in Anatomic Pathology, School of Medicine, University of Naples “Federico II”, Naples, Italy.
• 2016 – present: Professor for teaching activities in Anatomic Pathology, Neurophysiopathology Techniques degree, University of Naples “Federico II”, Naples, Italy.
• 2016 – present: Professor for teaching activities in Anatomic Pathology, audiometry and hearing aid degree, University of Naples “Federico II”, Naples, Italy.
• 2016 – present: Professor for teaching activities in Anatomic Pathology School, University of Naples “Federico II”, Naples, Italy.
• 2019-present: Chair of Young Investigators of International Society of Liquid Biopsy.
• 2020-present: Member of Revisors panel for Ph.D. students, University of Bologna, Bologna, Italy.
• 2020 – present: Member of "NETWORK ONCOLOGY AND PRECISION MEDICINE" Iinternational Ph.D. Program, University of Rome "La Sapienza", Rome, Italy.
• 2021 – present: Member of the Breast Unit, University of Naples “Federico II”, Naples, Italy.
• 2021 – present: Second Supervisor for the International PhD Course in Molecular Medicine, Curriculum in Experimental and clinical medicine, at the San Raffaele University in Milan, Italy
• 2021 – present: Second Supervisor for the Doctoral School in Life and Health Sciences PhD Program in Complex System for Life Sciences, at the University of Torino, Italy.
• 2021: UICC Virtual Fellowship. 18 May 2021. Clinical and Translational Research in Lung Cancer.



Editorial appointments:
• 2020-present: Editorial Board Member of Frontiers in Oncology for “Thoracic Oncology” specialty section as Associate Editor.
• 2020-present: Editorial Board Member of Frontiers in Oncology for “Women’s Cancer” specialty section as Associate Editor.
• 2020-present: Editorial Board Member of Critical Reviews in Oncology/Hematology as Deputy Editor.
• 2020-present: Editorial Board Member of Journal of Molecular Pathology as Associate Editor.
• 2020-present: Editorial Board Member of Cells as Associate Editor.


Technology transfer activities
• 2017 – present: Proposing member of the Spin – Off of the Department of Public Health, University of Naples “Federico II”, GENEDIN s.r.l. (Via Giovanni Devoti 14, 00167, Rome, Italy).
• Developer and owner (50%) of SiRe® panel (CE – IVD), a pool of oligonucleotidic probes for the characterization of the molecular assessment of preditictive genes of response to target therapies in metastatic colo-rectal carcinoma, non small cell lung cancer, melanoma and gastrointestinal stromal tumors.

Reviewer for International Project
- 2021: participated in the review process of the Dutch Cancer Society (KWF) for the call 2021-1

Expertise and My contribution to Molecular Predictive Pathology:

I graduated with a degree in biotechnology from the University of Naples “Federico II”, Italy in 2009, then I studied at the Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain as Research Partnership with the group of Prof. M. A. Pirirs. I obtained a PhD and Doctor Europaeus in Antomic Pathology from the University of Naples “Federico II”, Italy in 2013 under the direction of Professor Stefania Montagnani, then I collaborated at Pangaea Inst/Dexeus University, Barcelona, Spain in 2016 under the direction of Professor Rosell. I worked as researcher in the University of Naples, Italy from 2015 to today.
From 2008 to 2010 I worked as Research group member, Italy-Spain Partnership (MIUR grant, IT1816). Role of akt kinase in growth control of hematological and solid neoplasms. In collaboration with Dr. Miguel Angel Piris del Programa de Patologia Molecular Centro Nacional de Investigaciones Oncologicas Madrid, Spain.
In 2009 to 2012 I served as Project PRIN Member: Histological and immunohistochemical effects of combined administration of rapamycin, tolvaptan, and AEZ-131 on the progression of polycystic disease in PCK rats.
In 2015-in progress I am a Co-Investigator Research Project “Molecular Biology in indeterminate thyroid FNA” funded by Regione Campania (L.R. n. 24 del 29/12/2005).
From 2016 to today I am a Co-Investigator Research Project ”Traslation in clinical practice of ctDNA analysis for EGFR mutation in NSCLC patients” Promoter: Università degli Studi di Napoli Federico II.
I am an expert member of the International Society of Liquid Biopsy (ISLB) and I also serve as a board committee member of Italian Group of Molecular Pathology and Predictive Medicine (PMMP).
I am currently the Chief Suepervisor of the Molecular Pathology laboratory of Department of Public Health of University of Naples “Federico II”. My research is focused in molecular oncology and immunotherapy in thoracic oncology and in a pan-tumoral approach, using new genertion techniques in liquid biopsies, specifically in circulating free tumour DNA.
I am the developer of an NGS panel (Sire®) for the detection of clinical relevant mutations for NSCLC, GIST, mCRC and metastatic melanoma. I am the founder of University of Naples Spin – off (Genedin), involved in the developing of next generation procedure for detection and analysis of positive and negative biomarkers in the field of solid tumors.

Drafting Member of the Italian guidelines
- 2019 - present: AIOM – Lung neoplasms;
- 2020 - present: SIAPEC - Melanoma;
- 2020 - present: AIOM, SIAPEC, SIF, SIBICO – Molecular Predictive Pathology in cancer patients

Drafting Member of the International guidelines
- 2019 - present: International Association for the Study of Lung Cancer (IASLC) – Liquid biopsy in lung cancer

Papers:
1. Troncone G, Russo M, Malapelle U, Accardo M, Ferraro A, Cozzolino I, Palombini L. Cytological and molecular diagnosis of solid variant of papillary thyroid carcinoma: a case report. Cytojournal. 2008 Mar 19;5:2. doi: 10.1186/1742-6413-5-2. PMID: 18353179; PMCID: PMC2278161.
2. Troncone G, Cozzolino I, Fedele M, Malapelle U, Palombini L. Preparation of thyroid FNA material for routine cytology and BRAF testing: a validation study. Diagn Cytopathol. 2010 Mar;38(3):172-6. doi: 10.1002/dc.21166. PMID: 19693938.
3. Troncone G, Volante M, Iaccarino A, Zeppa P, Cozzolino I, Malapelle U, Palmieri EA, Conzo G, Papotti M, Palombini L. Cyclin D1 and D3 overexpression predicts malignant behavior in thyroid fine-needle aspirates suspicious for Hurthle cell neoplasms. Cancer. 2009 Dec 25;117(6):522-9. doi: 10.1002/cncy.20050. PMID: 19787802.
4. Troncone G, Malapelle U, Cozzolino I, Palombini L. KRAS mutation analysis on cytological specimens of metastatic colo-rectal cancer. Diagn Cytopathol. 2010 Dec;38(12):869-73. doi: 10.1002/dc.21302. PMID: 20049979.
5. Cozzolino I, Malapelle U, Carlomagno C, Palombini L, Troncone G. Metastasis of colon cancer to the thyroid gland: a case diagnosed on fine-needle aspirate by a combined cytological, immunocytochemical, and molecular approach. Diagn Cytopathol. 2010 Dec;38(12):932-5. doi: 10.1002/dc.21346. PMID: 20213843.
6. Malapelle U, Bellevicine C, Russo A, Salatiello M, Palombini L, Troncone G. KRAS testing on colo-rectal carcinoma cytological imprints. Diagn Cytopathol. 2011 Apr;39(4):274-7. doi: 10.1002/dc.21417. PMID: 20607679.
7. Malapelle U, Bellevicine C, Zeppa P, Palombini L, Troncone G. Cytology-based gene mutation tests to predict response to anti-epidermal growth factor receptor therapy: a review. Diagn Cytopathol. 2011 Sep;39(9):703-10. doi: 10.1002/dc.21512. Epub 2010 Nov 9. PMID: 21837660.
8. Malapelle U, de Rosa N, Rocco D, Bellevicine C, Crispino C, Illiano A, Piantedosi FV, Nappi O, Troncone G. EGFR and KRAS mutations detection on lung cancer liquid-based cytology: a pilot study. J Clin Pathol. 2012 Jan;65(1):87-91. doi: 10.1136/jclinpath-2011-200296. Epub 2011 Sep 22. PMID: 21945923.
9. Bellevicine C, Malapelle U, Docimo G, Ciancia G, Mossetti G, Pettinato G, Troncone G. Multicentric encapsulated papillary oncocytic neoplasm of the thyroid: A case diagnosed by a combined cytological, histological, immunohistochemical, and molecular approach. Diagn Cytopathol. 2012 May;40(5):450-4. doi: 10.1002/dc.21828. Epub 2011 Sep 30. PMID: 21965084.
10. Forzati F, Federico A, Pallante P, Abbate A, Esposito F, Malapelle U, Sepe R, Palma G, Troncone G, Scarfò M, Arra C, Fedele M, Fusco A. CBX7 is a tumor suppressor in mice and humans. J Clin Invest. 2012 Feb;122(2):612-23. doi: 10.1172/JCI58620. Epub 2012 Jan 3. Erratum in: J Clin Invest. 2013 Feb 1;123(2):934. PMID: 22214847; PMCID: PMC3266782.
11. Malapelle U, de Rosa N, Bellevicine C, Rocco D, Vitiello F, Piantedosi FV, Illiano A, Nappi O, Troncone G. EGFR mutations detection on liquid-based cytology: is microscopy still necessary? J Clin Pathol. 2012 Jun;65(6):561-4. doi: 10.1136/jclinpath-2011-200659. Epub 2012 Apr 1. PMID: 22466414.
12. Zeppa P, Sosa Fernandez LV, Cozzolino I, Ronga V, Genesio R, Salatiello M, Picardi M, Malapelle U, Troncone G, Vigliar E. Immunoglobulin heavy-chain fluorescence in situ hybridization-chromogenic in situ hybridization DNA probe split signal in the clonality assessment of lymphoproliferative processes on cytological samples. Cancer Cytopathol. 2012 Dec 25;120(6):390-400. doi: 10.1002/cncy.21203. Epub 2012 Apr 19. PMID: 22517675.
13. Malapelle U, Carlomagno C, Salatiello M, De Stefano A, De Luca C, Bianco R, Marciano R, Cimminiello C, Bellevicine C, De Placido S, Troncone G. KRAS mutation detection by high-resolution melting analysis significantly predicts clinical benefit of cetuximab in metastatic colorectal cancer. Br J Cancer. 2012 Aug 7;107(4):626-31. doi: 10.1038/bjc.2012.275. Epub 2012 Jul 17. PMID: 22805329; PMCID: PMC3419946.
14. Malapelle U, Bellevicine C, Salatiello M, de Luca C, Rispo E, Riccio P, Sparano L, De Stefano A, Carlomagno C, Maiello FM, Vita G, Nappi O, Troncone G. Sanger sequencing in routine KRAS testing: a review of 1720 cases from a pathologist's perspective. J Clin Pathol. 2012 Oct;65(10):940-4. doi: 10.1136/jclinpath-2012-200773. Epub 2012 Aug 7. PMID: 22872705; PMCID: PMC3461636.
15. Bellevicine C, Malapelle U, Iaccarino A, Schettino P, Napolitano V, Zeppa P, Troncone G. Foamy gland pancreatic ductal adenocarcinoma diagnosed on EUS-FNA: a histochemical, immunohistochemical, and molecular report. Diagn Cytopathol. 2013 Jan;41(1):77-80. doi: 10.1002/dc.22923. Epub 2012 Sep 25. PMID: 23008087.
16. Bellevicine C, Cozzolino I, Malapelle U, Zeppa P, Troncone G. Cytological and molecular features of papillary thyroid carcinoma with prominent hobnail features: a case report. Acta Cytol. 2012;56(5):560-4. doi: 10.1159/000338395. Epub 2012 Sep 27. PMID: 23075900.
17. Pallante P, Malapelle U, Berlingieri MT, Bellevicine C, Sepe R, Federico A, Rocco D, Galgani M, Chiariotti L, Sanchez-Cespedes M, Fusco A, Troncone G. UbcH10 overexpression in human lung carcinomas and its correlation with EGFR and p53 mutational status. Eur J Cancer. 2013 Mar;49(5):1117-26. doi: 10.1016/j.ejca.2012.09.033. Epub 2012 Oct 24. PMID: 23102841.
18. Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marfè G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R. Sphingosine kinase 1 overexpression contributes to cetuximab resistance in human colorectal cancer models. Clin Cancer Res. 2013 Jan 1;19(1):138-47. doi: 10.1158/1078-0432.CCR-12-1050. Epub 2012 Nov 19. PMID: 23166225.
19. Bellevicine C, Zabatta A, Malapelle U, Vetrani A, Troncone G. Diffuse large B-cell extranodal lymphoma of the uterine cervix: an incidental pap smear finding with histological and immunohistochemical correlation. Diagn Cytopathol. 2014 Jul;42(7):644-6. doi: 10.1002/dc.22966. Epub 2013 Feb 26. PMID: 23441015.
20. Bellevicine C, Iaccarino A, Malapelle U, Troncone G. Warthin tumor with signet-ring cell features as a pitfall in salivary gland cytopathology. Acta Cytol. 2013;57(3):309-12. doi: 10.1159/000348248. Epub 2013 Apr 25. PMID: 23635480.
21. Malapelle U, Bellevicine C, De Luca C, Salatiello M, De Stefano A, Rocco D, de Rosa N, Vitiello F, Russo S, Pepe F, Iaccarino A, Micheli P, Illiano A, Carlomagno C, Piantedosi FV, Troncone G. EGFR mutations detected on cytology samples by a centralized laboratory reliably predict response to gefitinib in non-small cell lung carcinoma patients. Cancer Cytopathol. 2013 Oct;121(10):552-60. doi: 10.1002/cncy.21322. Epub 2013 Jun 18. PMID: 23780873.
22. Malapelle U, Russo S, Pepe F, Sgariglia R, De Luca C, Bellevicine C, Pallante P, Troncone G. EGFR mutation detection by microfluidic technology: a validation study. J Clin Pathol. 2013 Nov;66(11):982-4. doi: 10.1136/jclinpath-2013-201730. Epub 2013 Jun 21. PMID: 23794480.
23. Bellevicine C, Iaccarino A, Malapelle U, Sasso FC, Biondi B, Troncone G. PAX8 is expressed in anaplastic thyroid carcinoma diagnosed by fine-needle aspiration: a study of three cases with histological correlates. Eur J Endocrinol. 2013 Jul 29;169(3):307-11. doi: 10.1530/EJE-13-0150. PMID: 23811186.
24. Malapelle U, Carlomagno C, de Luca C, Bellevicine C, Troncone G. KRAS testing in metastatic colorectal carcinoma: challenges, controversies, breakthroughs and beyond. J Clin Pathol. 2014 Jan;67(1):1-9. doi: 10.1136/jclinpath-2013-201835. Epub 2013 Sep 10. PMID: 24022727.
25. Bellevicine C, Vita GD, Malapelle U, Troncone G. Applications and limitations of oncogene mutation testing in clinical cytopathology. Semin Diagn Pathol. 2013 Nov;30(4):284-97. doi: 10.1053/j.semdp.2013.11.008. Epub 2013 Nov 12. PMID: 24342285.
26. de Biase D, Visani M, Malapelle U, Simonato F, Cesari V, Bellevicine C, Pession A, Troncone G, Fassina A, Tallini G. Next-generation sequencing of lung cancer EGFR exons 18-21 allows effective molecular diagnosis of small routine samples (cytology and biopsy). PLoS One. 2013 Dec 23;8(12):e83607. doi: 10.1371/journal.pone.0083607. PMID: 24376723; PMCID: PMC3871524.
27. Bellevicine C, Malapelle U, de Luca C, Iaccarino A, Troncone G. EGFR analysis: current evidence and future directions. Diagn Cytopathol. 2014 Nov;42(11):984-92. doi: 10.1002/dc.23142. Epub 2014 Mar 12. PMID: 24619906.
28. Bellevicine C, Bianco A, Malapelle U, De Luca C, Vigliar E, Cacciola NA, Pallante P, Troncone G. Performance of EGFR mutant-specific antibodies in different cytological preparations: a validation study. Cytopathology. 2015 Apr;26(2):99-105. doi: 10.1111/cyt.12155. Epub 2014 May 15. PMID: 24831172.
29. Della Vittoria Scarpati G, Calura E, Di Marino M, Romualdi C, Beltrame L, Malapelle U, Troncone G, De Stefano A, Pepe S, De Placido S, D'Incalci M, Marchini S, Carlomagno C. Analysis of differential miRNA expression in primary tumor and stroma of colorectal cancer patients. Biomed Res Int. 2014;2014:840921. doi: 10.1155/2014/840921. Epub 2014 Jul 10. PMID: 25143946; PMCID: PMC4128171.
30. Vigliar E, Malapelle U, Bellevicine C, de Luca C, Troncone G. Outsourcing cytological samples to a referral laboratory for EGFR testing in non-small cell lung cancer: does theory meet practice? Cytopathology. 2015 Oct;26(5):312-7. doi: 10.1111/cyt.12221. Epub 2014 Nov 7. PMID: 25376259.
31. Malapelle U, Vigliar E, Sgariglia R, Bellevicine C, Colarossi L, Vitale D, Pallante P, Troncone G. Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients. J Clin Pathol. 2015 Jan;68(1):64-8. doi: 10.1136/jclinpath-2014-202691. Epub 2014 Nov 5. PMID: 25378536.
32. Bellevicine C, Malapelle U, Vigliar E, de Luca C, Troncone G. Epidermal growth factor receptor test performed on liquid-based cytology lung samples: experience of an academic referral center. Acta Cytol. 2014;58(6):589-94. doi: 10.1159/000369756. Epub 2014 Nov 22. PMID: 25428205.
33. Malapelle U, Sgariglia R, De Stefano A, Bellevicine C, Vigliar E, de Biase D, Sepe R, Pallante P, Carlomagno C, Tallini G, Troncone G. KRAS mutant allele-specific imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer. J Clin Pathol. 2015 Apr;68(4):265-9. doi: 10.1136/jclinpath-2014-202761. Epub 2015 Jan 21. PMID: 25609577.
34. Bellevicine C, Vigliar E, Malapelle U, Pisapia P, Conzo G, Biondi B, Vetrani A, Troncone G. Cytopathologists can reliably perform ultrasound-guided thyroid fine needle aspiration: a 1-year audit on 3715 consecutive cases. Cytopathology. 2016 Apr;27(2):115-21. doi: 10.1111/cyt.12243. Epub 2015 Mar 21. PMID: 25810099.
35. Bellevicine C, Vigliar E, Malapelle U, Carelli E, Fiorelli A, Vicidomini G, Cappabianca S, Santini M, Troncone G. Lung adenocarcinoma and its thyroid metastasis characterized on fine-needle aspirates by cytomorphology, immunocytochemistry, and next-generation sequencing. Diagn Cytopathol. 2015 Jul;43(7):585-9. doi: 10.1002/dc.23264. Epub 2015 Apr 21. PMID: 25900221.
36. Cacciola NA, Calabrese C, Malapelle U, Pellino G, De Stefano A, Sepe R, Sgariglia R, Quintavalle C, Federico A, Bianco A, Uchimura Bastos A, Milone M, Bellevicine C, Milone F, Carlomagno C, Selvaggi F, Troncone G, Fusco A, Pallante P. UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients. Mol Carcinog. 2016 May;55(5):793-807. doi: 10.1002/mc.22322. Epub 2015 Apr 27. PMID: 25917796.
37. Malapelle U, Vatrano S, Russo S, Bellevicine C, de Luca C, Sgariglia R, Rocco D, de Pietro L, Riccardi F, Gobbini E, Righi L, Troncone G. EGFR mutant allelic-specific imbalance assessment in routine samples of non-small cell lung cancer. J Clin Pathol. 2015 Sep;68(9):739-41. doi: 10.1136/jclinpath-2015-203101. Epub 2015 Jun 5. PMID: 26047622.
38. Della Corte CM, Bellevicine C, Vicidomini G, Vitagliano D, Malapelle U, Accardo M, Fabozzi A, Fiorelli A, Fasano M, Papaccio F, Martinelli E, Troiani T, Troncone G, Santini M, Bianco R, Ciardiello F, Morgillo F. SMO Gene Amplification and Activation of the Hedgehog Pathway as Novel Mechanisms of Resistance to Anti-Epidermal Growth Factor Receptor Drugs in Human Lung Cancer. Clin Cancer Res. 2015 Oct 15;21(20):4686-97. doi: 10.1158/1078-0432.CCR-14-3319. Epub 2015 Jun 29. PMID: 26124204.
39. Malapelle U, De Stefano A, Carlomagno C, Bellevicine C, Troncone G. Next-generation sequencing in the genomic profiling of synchronous colonic carcinomas: comment on Li et al (2015). J Clin Pathol. 2015 Nov;68(11):946-7. doi: 10.1136/jclinpath-2015-203205. Epub 2015 Jul 2. PMID: 26139632.
40. Lucci R, Vigliar E, Malapelle U, Cigliano B, Troncone G, Bellevicine C. Fine-needle aspiration findings in focal (nodular) myositis of a newborn: A case report. Diagn Cytopathol. 2015 Nov;43(11):920-3. doi: 10.1002/dc.23309. Epub 2015 Jul 14. PMID: 26173198.
41. Vigliar E, Malapelle U, Troncone G. Cytopathology meets basic science. Cancer Cytopathol. 2015 Oct;123(10):571-2. doi: 10.1002/cncy.21578. Epub 2015 Jul 20. PMID: 26194340.
42. Cacciola NA, Sepe R, Forzati F, Federico A, Pellecchia S, Malapelle U, De Stefano A, Rocco D, Fusco A, Pallante P. Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1179-86. doi: 10.1007/s00210-015-1153-y. Epub 2015 Jul 28. PMID: 26216446.
43. Vigliar E, Malapelle U, de Luca C, Bellevicine C, Troncone G. Challenges and opportunities of next-generation sequencing: a cytopathologist's perspective. Cytopathology. 2015 Oct;26(5):271-83. doi: 10.1111/cyt.12265. PMID: 26399861.
44. Pellino G, Pallante P, Malapelle U, Ferraro A, Bellevicine C, Milone M, Troncone G, Fusco A, Selvaggi F; INSIghT-R Collaborative. UbcH10 overexpression is less pronounced in older colorectal cancer patients. Int J Colorectal Dis. 2016 Jul;31(7):1367-8. doi: 10.1007/s00384-015-2481-6. Epub 2016 Jan 7. PMID: 26744065.
45. Malapelle U, Pisapia P, Sgariglia R, Vigliar E, Biglietto M, Carlomagno C, Giuffrè G, Bellevicine C, Troncone G. Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases. J Clin Pathol. 2016 Sep;69(9):767-71. doi: 10.1136/jclinpath-2015-203403. Epub 2016 Jan 21. PMID: 26797410; PMCID: PMC5036215.
46. Malapelle U, de Luca C, Vigliar E, Ambrosio F, Rocco D, Pisapia P, Bellevicine C, Troncone G. EGFR mutation detection on routine cytological smears of non-small cell lung cancer by digital PCR: a validation study. J Clin Pathol. 2016 May;69(5):454-7. doi: 10.1136/jclinpath-2015-203429. Epub 2016 Feb 18. PMID: 26893402.
47. de Biase D, de Luca C, Gragnano G, Visani M, Bellevicine C, Malapelle U, Tallini G, Troncone G. Fully automated PCR detection of KRAS mutations on pancreatic endoscopic ultrasound fine-needle aspirates. J Clin Pathol. 2016 Apr 27:jclinpath-2016-203696. doi: 10.1136/jclinpath-2016-203696. Epub ahead of print. PMID: 27122185.
48. Malapelle U, Morra F, Ilardi G, Visconti R, Merolla F, Cerrato A, Napolitano V, Monaco R, Guggino G, Monaco G, Staibano S, Troncone G, Celetti A. USP7 inhibitors, downregulating CCDC6, sensitize lung neuroendocrine cancer cells to PARP-inhibitor drugs. Lung Cancer. 2017 May;107:41-49. doi: 10.1016/j.lungcan.2016.06.015. Epub 2016 Jun 17. PMID: 27372520.
49. De Luca C, Gragnano G, Pisapia P, Vigliar E, Malapelle U, Bellevicine C, Troncone G. EGFR mutation detection on lung cancer cytological specimens by the novel fully automated PCR-based Idylla EGFR Mutation Assay. J Clin Pathol. 2017 Apr;70(4):295-300. doi: 10.1136/jclinpath-2016-203989. Epub 2016 Aug 19. PMID: 27543600.
50. Bellevicine C, Sgariglia R, Malapelle U, Vigliar E, Nacchio M, Ciancia G, Eszlinger M, Paschke R, Troncone G. Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next-generation sequencing of thyroid FNA samples? Cancer Cytopathol. 2016 Nov;124(11):776-784. doi: 10.1002/cncy.21780. Epub 2016 Sep 26. PMID: 27717198.
51. Malapelle U, Pisapia P, Rocco D, Smeraglio R, di Spirito M, Bellevicine C, Troncone G. Next generation sequencing techniques in liquid biopsy: focus on non-small cell lung cancer patients. Transl Lung Cancer Res. 2016 Oct;5(5):505-510. doi: 10.21037/tlcr.2016.10.08. PMID: 27826531; PMCID: PMC5099511.
52. Pepe F, Smeraglio R, Vacirca D, Malapelle U, Barberis M, Troncone G. Microsatellite instability evaluation by automated microfluidic electrophoresis: an update. J Clin Pathol. 2017 Jan;70(1):90-91. doi: 10.1136/jclinpath-2016-204200. Epub 2016 Nov 21. PMID: 27872139.
53. Cortinovis D, Gregorc V, Migliorino MR, Abate MI, Manzo A, Malapelle U, Morabito A; Italian Lung Cancer Working Group. New perspectives in the second-line treatment of non squamous NSCLC patients: Results from a large Italian Lung Cancer Working Group. Crit Rev Oncol Hematol. 2017 Jan;109:35-41. doi: 10.1016/j.critrevonc.2016.11.015. Epub 2016 Nov 25. PMID: 28010896.
54. D'Argenio V, Torino M, Precone V, Casaburi G, Esposito MV, Iaffaldano L, Malapelle U, Troncone G, Coto I, Cavalcanti P, De Rosa G, Salvatore F, Sacchetti L. The Cause of Death of a Child in the 18th Century Solved by Bone Microbiome Typing Using Laser Microdissection and Next Generation Sequencing. Int J Mol Sci. 2017 Jan 6;18(1):109. doi: 10.3390/ijms18010109. PMID: 28067829; PMCID: PMC5297743.
55. Malapelle U, Sirera R, Jantus-Lewintre E, Reclusa P, Calabuig-Fariñas S, Blasco A, Pisapia P, Rolfo C, Camps C. Profile of the Roche cobas® EGFR mutation test v2 for non-small cell lung cancer. Expert Rev Mol Diagn. 2017 Mar;17(3):209-215. doi: 10.1080/14737159.2017.1288568. Epub 2017 Feb 9. Erratum in: Expert Rev Mol Diagn. 2017 Mar;17 (3):i. PMID: 28129709.
56. Malapelle U, Mayo de-Las-Casas C, Rocco D, Garzon M, Pisapia P, Jordana-Ariza N, Russo M, Sgariglia R, De Luca C, Pepe F, Martinez-Bueno A, Morales-Espinosa D, González-Cao M, Karachaliou N, Viteri Ramirez S, Bellevicine C, Molina-Vila MA, Rosell R, Troncone G. Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients. Br J Cancer. 2017 Mar 14;116(6):802-810. doi: 10.1038/bjc.2017.8. Epub 2017 Feb 7. PMID: 28170370; PMCID: PMC5355934.
57. Forzati F, De Martino M, Esposito F, Sepe R, Pellecchia S, Malapelle U, Pellino G, Arra C, Fusco A. miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene. BMC Cancer. 2017 Mar 4;17(1):170. doi: 10.1186/s12885-017-3158-z. PMID: 28259135; PMCID: PMC5336640.
58. De Luca C, Vigliar E, d'Anna M, Pisapia P, Bellevicine C, Malapelle U, Troncone G. KRAS detection on archival cytological smears by the novel fully automated polymerase chain reaction-based Idylla mutation test. Cytojournal. 2017 Feb 24;14:5. doi: 10.4103/1742-6413.200936. PMID: 28331530; PMCID: PMC5348988.
59. Clery E, Pisapia P, Feliciano S, Vigliar E, Marano A, De Luca C, Malapelle U, Troncone G, Bellevicine C. There is still a role for cytology in the 'liquid biopsy' era. A lesson from a TKI-treated patient showing adenocarcinoma to squamous cell carcinoma transition during disease progression. J Clin Pathol. 2017 Sep;70(9):798-802. doi: 10.1136/jclinpath-2017-204370. Epub 2017 Mar 31. PMID: 28363898.
60. Sgariglia R, Pisapia P, Nacchio M, De Luca C, Pepe F, Russo M, Bellevicine C, Troncone G, Malapelle U. Multiplex digital colour-coded barcode technology on RNA extracted from routine cytological samples of patients with non-small cell lung cancer: pilot study. J Clin Pathol. 2017 Sep;70(9):803-806. doi: 10.1136/jclinpath-2017-204373. Epub 2017 Apr 6. PMID: 28385922.
61. Della Corte CM, Malapelle U, Vigliar E, Pepe F, Troncone G, Ciaramella V, Troiani T, Martinelli E, Belli V, Ciardiello F, Morgillo F. Efficacy of continuous EGFR-inhibition and role of Hedgehog in EGFR acquired resistance in human lung cancer cells with activating mutation of EGFR. Oncotarget. 2017 Apr 4;8(14):23020-23032. doi: 10.18632/oncotarget.15479. PMID: 28416737; PMCID: PMC5410282.
62. Malapelle U, Mayo-de-Las-Casas C, Molina-Vila MA, Rosell R, Savic S, Bihl M, Bubendorf L, Salto-Tellez M, de Biase D, Tallini G, Hwang DH, Sholl LM, Luthra R, Weynand B, Vander Borght S, Missiaglia E, Bongiovanni M, Stieber D, Vielh P, Schmitt F, Rappa A, Barberis M, Pepe F, Pisapia P, Serra N, Vigliar E, Bellevicine C, Fassan M, Rugge M, de Andrea CE, Lozano MD, Basolo F, Fontanini G, Nikiforov YE, Kamel-Reid S, da Cunha Santos G, Nikiforova MN, Roy-Chowdhuri S, Troncone G; Molecular Cytopathology Meeting Group. Consistency and reproducibility of next-generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens. Cancer Cytopathol. 2017 Aug;125(8):615-626. doi: 10.1002/cncy.21868. Epub 2017 May 5. PMID: 28475299.
63. Malapelle U, Pallante P. Editorial: Second Line Treatment of Non-Small Cell Lung Cancer: Clinical, Pathological and Molecular Aspects of Novel Promising Drugs. Front Med (Lausanne). 2017 May 22;4:63. doi: 10.3389/fmed.2017.00063. PMID: 28589123; PMCID: PMC5439169.
64. De Stefano A, Rosanova M, Malapelle U, Martini M, De Falco S, Attademo L, Fiore G, Cenci T, Bellevicine C, De Placido S, Troncone G, Carlomagno C. Discordance in RAS mutations between primary colon tumor and metastases: a real event or a matter of methodology? Int J Biol Markers. 2017 Oct 31;32(4):e474-e477. doi: 10.5301/ijbm.5000273. PMID: 28665451.
65. Bellevicine C, Malapelle U, Vigliar E, Pisapia P, Vita G, Troncone G. How to prepare cytological samples for molecular testing. J Clin Pathol. 2017 Oct;70(10):819-826. doi: 10.1136/jclinpath-2017-204561. Epub 2017 Jul 24. PMID: 28739858.
66. Pisapia P, Lozano MD, Vigliar E, Bellevicine C, Pepe F, Malapelle U, Troncone G. ALK and ROS1 testing on lung cancer cytologic samples: Perspectives. Cancer Cytopathol. 2017 Nov;125(11):817-830. doi: 10.1002/cncy.21899. Epub 2017 Jul 25. PMID: 28743163.
67. Mayo-de-Las-Casas C, Garzón Ibáñez M, Jordana-Ariza N, García-Peláez B, Balada-Bel A, Villatoro S, Malapelle U, Karachaliou N, Troncone G, Rosell R, Molina-Vila MA. An update on liquid biopsy analysis for diagnostic and monitoring applications in non-small cell lung cancer. Expert Rev Mol Diagn. 2018 Jan;18(1):35-45. doi: 10.1080/14737159.2018.1407243. Epub 2017 Nov 26. PMID: 29172773.
68. Pisapia P, Pepe F, Smeraglio R, Russo M, Rocco D, Sgariglia R, Nacchio M, De Luca C, Vigliar E, Bellevicine C, Troncone G, Malapelle U. Cell free DNA analysis by SiRe® next generation sequencing panel in non small cell lung cancer patients: focus on basal setting. J Thorac Dis. 2017 Oct;9(Suppl 13):S1383-S1390. doi: 10.21037/jtd.2017.06.97. PMID: 29184677; PMCID: PMC5676109.
69. Bellevicine C, Sgariglia R, Migliatico I, Vigliar E, D'Anna M, Nacchio MA, Serra N, Malapelle U, Bongiovanni M, Troncone G. Different qualifiers of AUS/FLUS thyroid FNA have distinct BRAF, RAS, RET/PTC, and PAX8/PPARg alterations. Cancer Cytopathol. 2018 May;126(5):317-325. doi: 10.1002/cncy.21984. Epub 2018 Feb 22. PMID: 29469940.
70. Bianco A, Malapelle U, Rocco D, Perrotta F, Mazzarella G. Targeting immune checkpoints in non small cell lung cancer. Curr Opin Pharmacol. 2018 Jun;40:46-50. doi: 10.1016/j.coph.2018.02.006. Epub 2018 Mar 9. PMID: 29525401.
71. Della Corte CM, Ciaramella V, Cardone C, La Monica S, Alfieri R, Petronini PG, Malapelle U, Vigliar E, Pepe F, Troncone G, Castellone MD, Troiani T, Martinelli E, Ciardiello F, Morgillo F. Antitumor Efficacy of Dual Blockade of EGFR Signaling by Osimertinib in Combination With Selumetinib or Cetuximab in Activated EGFR Human NCLC Tumor Models. J Thorac Oncol. 2018 Jun;13(6):810-820. doi: 10.1016/j.jtho.2018.02.025. Epub 2018 Mar 8. PMID: 29526823.
72. De Luca C, Rappa AG, Gragnano G, Malapelle U, Troncone G, Barberis M. Idylla assay and next generation sequencing: an integrated EGFR mutational testing algorithm. J Clin Pathol. 2018 Aug;71(8):745-750. doi: 10.1136/jclinpath-2018-205197. Epub 2018 May 24. PMID: 29798838.
73. Bruera G, Pepe F, Malapelle U, Pisapia P, Mas AD, Di Giacomo D, Calvisi G, Troncone G, Ricevuto E. KRAS, NRAS and BRAF mutations detected by next generation sequencing, and differential clinical outcome in metastatic colorectal cancer (MCRC) patients treated with first line FIr-B/FOx adding bevacizumab (BEV) to triplet chemotherapy. Oncotarget. 2018 May 29;9(41):26279-26290. doi: 10.18632/oncotarget.25180. PMID: 29899858; PMCID: PMC5995185.
74. Pellino G, Gallo G, Pallante P, Capasso R, De Stefano A, Maretto I, Malapelle U, Qiu S, Nikolaou S, Barina A, Clerico G, Reginelli A, Giuliani A, Sciaudone G, Kontovounisios C, Brunese L, Trompetto M, Selvaggi F. Noninvasive Biomarkers of Colorectal Cancer: Role in Diagnosis and Personalised Treatment Perspectives. Gastroenterol Res Pract. 2018 Jun 13;2018:2397863. doi: 10.1155/2018/2397863. PMID: 30008744; PMCID: PMC6020538.
75. Malapelle U, Ricciuti B, Baglivo S, Pepe F, Pisapia P, Anastasi P, Tazza M, Sidoni A, Liberati AM, Bellezza G, Chiari R, Metro G. Osimertinib. Recent Results Cancer Res. 2018;211:257-276. doi: 10.1007/978-3-319-91442-8_18. PMID: 30069773.
76. Pepe F, De Luca C, Smeraglio R, Pisapia P, Sgariglia R, Nacchio M, Russo M, Serra N, Rocco D, Battiloro C, Ambrosio F, Gragnano G, Vigliar E, Bellevicine C, Troncone G, Malapelle U. Performance analysis of SiRe next-generation sequencing panel in diagnostic setting: focus on NSCLC routine samples. J Clin Pathol. 2019 Jan;72(1):38-45. doi: 10.1136/jclinpath-2018-205386. Epub 2018 Oct 2. PMID: 30279174.
77. Capo A, Sepe R, Pellino G, Milone M, Malapelle U, Pellecchia S, Pepe F, Cacciola NA, Manigrasso M, Bruzzaniti S, Sciaudone G, De Palma GD, Galgani M, Selvaggi F, Troncone G, Fusco A, D'Auria S, Pallante P. Setting up and exploitation of a nano/technological platform for the evaluation of HMGA1b protein in peripheral blood of cancer patients. Nanomedicine. 2019 Jan;15(1):231-242. doi: 10.1016/j.nano.2018.09.011. Epub 2018 Oct 9. PMID: 30308301.
78. Scimia M, Du J, Pepe F, Bianco MA, Russo Spena S, Patell-Socha F, Sun Q, Powell MJ, Malapelle U*, Troncone G. Evaluation of a novel liquid biopsy-based ColoScape assay for mutational analysis of colorectal neoplasia and triage of FIT+ patients: a pilot study. J Clin Pathol. 2018 Dec;71(12):1123-1126. doi: 10.1136/jclinpath-2018-205412. Epub 2018 Oct 12. PMID: 30315134. (*corresponding author)
79. Malapelle U, Iaccarino A, Rossi A. Cytology versus histology for programmed death-ligand 1 expression evaluation in the landscape of non-small cell lung cancer patients selection for immunotherapy. Transl Lung Cancer Res. 2018 Sep;7(Suppl 3):S221-S224. doi: 10.21037/tlcr.2018.08.09. PMID: 30393607; PMCID: PMC6193894.
80. Pisapia P, Malapelle U, Troncone G. Liquid Biopsy and Lung Cancer. Acta Cytol. 2019;63(6):489-496. doi: 10.1159/000492710. Epub 2018 Dec 19. PMID: 30566947.
81. Capalbo C, Belardinilli F, Raimondo D, Milanetti E, Malapelle U, Pisapia P, Magri V, Prete A, Pecorari S, Colella M, Coppa A, Bonfiglio C, Nicolussi A, Valentini V, Tessitore A, Cardinali B, Petroni M, Infante P, Santoni M, Filetti M, Colicchia V, Paci P, Mezi S, Longo F, Cortesi E, Marchetti P, Troncone G, Bellavia D, Canettieri G, Giannini G. A Simplified Genomic Profiling Approach Predicts Outcome in Metastatic Colorectal Cancer. Cancers (Basel). 2019 Jan 27;11(2):147. doi: 10.3390/cancers11020147. PMID: 30691222; PMCID: PMC6406354.
82. Malapelle U, Raez LE, Serrano MJ, Rolfo C; International Society of Liquid Biopsies (ISLB). Detection of epidermal growth factor receptor mutations in circulating tumor DNA: reviewing BENEFIT clinical trial. J Thorac Dis. 2018 Dec;10(12):6388-6391. doi: 10.21037/jtd.2018.11.22. PMID: 30746171; PMCID: PMC6344757.
83. Pallante P, Pisapia P, Bellevicine C, Malapelle U, Troncone G. Circulating Tumour Cells in Predictive Molecular Pathology: Focus on Drug-Sensitive Assays and 3D Culture. Acta Cytol. 2019;63(3):171-181. doi: 10.1159/000496213. Epub 2019 Feb 13. PMID: 30759433.
84. Pisapia P, Pepe F, Malapelle U, Troncone G. BRAF Mutations in Lung Cancer. Acta Cytol. 2019;63(3):247-250. doi: 10.1159/000496478. Epub 2019 Mar 6. PMID: 30840950.
85. Vigliar E, Malapelle U, Iaccarino A, Acanfora G, Pisapia P, Clery E, De Luca C, Bellevicine C, Troncone G. PD-L1 expression on routine samples of non-small cell lung cancer: results and critical issues from a 1-year experience of a centralised laboratory. J Clin Pathol. 2019 Jun;72(6):412-417. doi: 10.1136/jclinpath-2019-205732. Epub 2019 Mar 7. PMID: 30846480.
86. Friedlaender A, Banna G, Malapelle U, Pisapia P, Addeo A. Next Generation Sequencing and Genetic Alterations in Squamous Cell Lung Carcinoma: Where Are We Today? Front Oncol. 2019 Mar 19;9:166. doi: 10.3389/fonc.2019.00166. PMID: 30941314; PMCID: PMC6433884.
87. Clery E, Pisapia P, Vigliar E, Malapelle U, Bellevicine C, Troncone G, Schmitt FC. Role of Cytomorphology in the Era of Liquid Biopsy. Acta Cytol. 2019;63(6):497-505. doi: 10.1159/000499338. Epub 2019 Apr 3. PMID: 30943469.
88. Vigliar E, Pepe F, Migliatico I, Nacchio M, Cesaro S, Della Pepa R, Bellevicine C, Malapelle U, Fassan M, Pane F, Picardi M, Troncone G. Microfluidic chip technology applied to fine-needle aspiration cytology samples for IGH clonality assessment. Diagn Cytopathol. 2019 Aug;47(8):749-757. doi: 10.1002/dc.24184. Epub 2019 Apr 5. PMID: 30953406.
89. Schirripa M, Biason P, Lonardi S, Pella N, Pino MS, Urbano F, Antoniotti C, Cremolini C, Corallo S, Pietrantonio F, Gelsomino F, Cascinu S, Orlandi A, Munari G, Malapelle U, Saggio S, Fontanini G, Rugge M, Mescoli C, Lazzi S, Reggiani Bonetti L, Lanza G, Dei Tos AP, De Maglio G, Martini M, Bergamo F, Zagonel V, Loupakis F, Fassan M. Class 1, 2, and 3 BRAF-Mutated Metastatic Colorectal Cancer: A Detailed Clinical, Pathologic, and Molecular Characterization. Clin Cancer Res. 2019 Jul 1;25(13):3954-3961. doi: 10.1158/1078-0432.CCR-19-0311. Epub 2019 Apr 9. PMID: 30967421.
90. Pisapia P*, Malapelle U*, Roma G, Saddar S, Zheng Q, Pepe F, Bruzzese D, Vigliar E, Bellevicine C, Luthra R, Nikiforov YE, Mayo-de-Las-Casas C, Molina-Vila MA, Rosell R, Bihl M, Savic S, Bubendorf L, de Biase D, Tallini G, Hwang DH, Sholl LM, Vander Borght S, Weynand B, Stieber D, Vielh P, Rappa A, Barberis M, Fassan M, Rugge M, De Andrea CE, Lozano MD, Lupi C, Fontanini G, Schmitt F, Dumur CI, Bisig B, Bongiovanni M, Merkelbach-Bruse S, Büttner R, Nikiforova MN, Roy-Chowdhuri S, Troncone G; Molecular Cytopathology Meeting Group. Consistency and reproducibility of next-generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens. Cancer Cytopathol. 2019 May;127(5):285-296. doi: 10.1002/cncy.22134. Epub 2019 Apr 25. PMID: 31021538. (*equal contribution)
91. Malapelle U, Rossi A. Emerging angiogenesis inhibitors for non-small cell lung cancer. Expert Opin Emerg Drugs. 2019 Jun;24(2):71-81. doi: 10.1080/14728214.2019.1619696. Epub 2019 May 22. PMID: 31092048.
92. De Luca C, Conticelli F, Leone A, Gragnano G, Salatiello M, Galasso P, Pisapia P, Grillo LR, Iaccarino A, Vigliar E, Bellevicine C, Malapelle U, Troncone G. Is the Idylla EGFR Mutation Assay feasible on archival stained cytological smears? A pilot study. J Clin Pathol. 2019 Sep;72(9):609-614. doi: 10.1136/jclinpath-2019-205863. Epub 2019 May 20. PMID: 31110050.
93. Vigliar E, Malapelle U, Bono F, Fusco N, Cortinovis D, Valtorta E, Spyridon A, Bimbatti M, Zocchi M, Piva C, Gaudioso G, Iaccarino A, Morbini P, Pagni F. The Reproducibility of the Immunohistochemical PD-L1 Testing in Non-Small-Cell Lung Cancer: A Multicentric Italian Experience. Biomed Res Int. 2019 Apr 14;2019:6832909. doi: 10.1155/2019/6832909. PMID: 31111063; PMCID: PMC6487144.
94. Pisapia P, Bellevicine C, Malapelle U, De Luca C, Vigliar E, Troncone G. Bird's eye view of modern cytopathology: Report from the seventh international Molecular Cytopathology Meeting in Naples, Italy, 2018. Cancer Cytopathol. 2019 Jun;127(6):350-357. doi: 10.1002/cncy.22118. Epub 2019 May 28. PMID: 31135103.
95. Signorelli D, Giannatempo P, Grazia G, Aiello MM, Bertolini F, Mirabile A, Buti S, Vasile E, Scotti V, Pisapia P, Cona MS, Rolfo C, Malapelle U*; Immune-Oncology YOUNG Group. Patients Selection for Immunotherapy in Solid Tumors: Overcome the Naïve Vision of a Single Biomarker. Biomed Res Int. 2019 Apr 24;2019:9056417. doi: 10.1155/2019/9056417. PMID: 31179334; PMCID: PMC6507101. (*corresponding author)
96. Bruera G, Massacese S, Pepe F, Malapelle U, Dal Mas A, Ciacco E, Calvisi G, Troncone G, Simmaco M, Ricevuto E. Intensive first-line FIr-C/FOx-C association of triplet chemotherapy plus cetuximab in RAS wild-type metastatic colorectal cancer patients: preliminary phase II data and prediction of individual limiting toxicity syndromes by pharmacogenomic biomarkers. Ther Adv Med Oncol. 2019 May 10;11:1758835919846421. doi: 10.1177/1758835919846421. PMID: 31205502; PMCID: PMC6535746.
97. Banna GL, Olivier T, Rundo F, Malapelle U, Fraggetta F, Libra M, Addeo A. The Promise of Digital Biopsy for the Prediction of Tumor Molecular Features and Clinical Outcomes Associated With Immunotherapy. Front Med (Lausanne). 2019 Jul 31;6:172. doi: 10.3389/fmed.2019.00172. PMID: 31417906; PMCID: PMC6685050.
98. Covelli C, Parente P, Pepe F, Pisapia P, Fiordelisi F, Malapelle U. Mismatch repair proteins and microsatellite instability in solid pseudopapillary neoplasm of the pancreas. Hepatobiliary Pancreat Dis Int. 2019 Oct;18(5):491-492. doi: 10.1016/j.hbpd.2019.08.003. Epub 2019 Aug 22. PMID: 31477525.
99. Malapelle U, Rolfo C; International Society of Liquid Biopsy (ISLB). Liquid biopsy as a follow-up tool: Comment on longitudinal monitoring of somatic genetic alterations in circulating cell-free DNA during treatment with epidermal growth factor receptor-tyrosine kinase inhibitors. Cancer. 2020 Jan 1;126(1):22-25. doi: 10.1002/cncr.32482. Epub 2019 Sep 10. PMID: 31503330.
100. Villatoro S, Mayo-de-Las-Casas C, Jordana-Ariza N, Viteri-Ramírez S, Garzón-Ibañez M, Moya-Horno I, García-Peláez B, González-Cao M, Malapelle U, Balada-Bel A, Martínez-Bueno A, Campos R, Reguart N, Majem M, Blanco R, Blasco A, Catalán MJ, González X, Troncone G, Karachaliou N, Rosell R, Molina-Vila MA. Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions. Mol Oncol. 2019 Dec;13(12):2633-2645. doi: 10.1002/1878-0261.12574. Epub 2019 Oct 11. PMID: 31529604; PMCID: PMC6887582.
101. Malapelle U*. USP11 role in colorectal cancer growing and metastatisation. EBioMedicine. 2019 Oct;48:5-6. doi: 10.1016/j.ebiom.2019.09.022. Epub 2019 Sep 17. PMID: 31537502; PMCID: PMC6838450. (*corresponding author)
102. Bianco A, Perrotta F, Barra G, Malapelle U, Rocco D, De Palma R. Prognostic Factors and Biomarkers of Responses to Immune Checkpoint Inhibitors in Lung Cancer. Int J Mol Sci. 2019 Oct 5;20(19):4931. doi: 10.3390/ijms20194931. PMID: 31590386; PMCID: PMC6801651.
103. Russo A, De Miguel Perez D, Gunasekaran M, Scilla K, Lapidus R, Cooper B, Mehra R, Adamo V, Malapelle U, Rolfo C. Liquid biopsy tracking of lung tumor evolutions over time. Expert Rev Mol Diagn. 2019 Dec;19(12):1099-1108. doi: 10.1080/14737159.2020.1680287. Epub 2019 Oct 16. PMID: 31608732.
104. Malapelle U, Rossi A, Bria E. Relationship between performance status or younger age and osimertinib therapy in T790M-positive NSCLC: are the available data convincing? J Thorac Dis. 2019 Sep;11(Suppl 15):S1837-S1840. doi: 10.21037/jtd.2019.08.99. PMID: 31632763; PMCID: PMC6783785.
105. Pagni F, Guerini-Rocco E, Schultheis AM, Grazia G, Rijavec E, Ghidini M, Lopez G, Venetis K, Croci GA, Malapelle U, Fusco N. Targeting Immune-Related Biological Processes in Solid Tumors: We do Need Biomarkers. Int J Mol Sci. 2019 Nov 1;20(21):5452. doi: 10.3390/ijms20215452. PMID: 31683784; PMCID: PMC6862285.
106. Lettig L, Sahnane N, Pepe F, Cerutti R, Albeni C, Franzi F, Veronesi G, Ogliari F, Pastore A, Tuzi A, Pinotti G, Bovio A, Verusio C, Giordano M, Troncone G, Sessa F, Malapelle U, Furlan D. EGFR T790M detection rate in lung adenocarcinomas at baseline using droplet digital PCR and validation by ultra-deep next generation sequencing. Transl Lung Cancer Res. 2019 Oct;8(5):584-592. doi: 10.21037/tlcr.2019.09.18. PMID: 31737495; PMCID: PMC6835109.
107. Passiglia F, Calandri M, Guerrera F, Malapelle U, Mangone L, Ramella S, Trisolini R, Novello S. Lung Cancer in Italy. J Thorac Oncol. 2019 Dec;14(12):2046-2052. doi: 10.1016/j.jtho.2019.05.019. PMID: 31757374.
108. Bellevicine C, Migliatico I, Sgariglia R, Nacchio M, Vigliar E, Pisapia P, Iaccarino A, Bruzzese D, Fonderico F, Salvatore D, Biondi B, Masone S, Novizio V, Scavuzzo F, Serino D, De Palma M, Chiofalo MG, Botti G, Pezzullo L, Nuzzo V, Spiezia S, De Chiara G, Iorio S, Conzo G, Docimo G, Faggiano A, Bongiovanni M, Malapelle U, Colao A, Triassi M, Troncone G; Tiroide Network. Evaluation of BRAF, RAS, RET/PTC, and PAX8/PPARg alterations in different Bethesda diagnostic categories: A multicentric prospective study on the validity of the 7-gene panel test in 1172 thyroid FNAs deriving from different hospitals in South Italy. Cancer Cytopathol. 2020 Feb;128(2):107-118. doi: 10.1002/cncy.22217. Epub 2019 Dec 10. PMID: 31821746.
109. Pepe F, Pisapia P, Del Basso de Caro ML, Conticelli F, Malapelle U, Troncone G, Martinez JC. Next generation sequencing identifies novel potential actionable mutations for grade I meningioma treatment. Histol Histopathol. 2020 Jul;35(7):741-749. doi: 10.14670/HH-18-195. Epub 2019 Dec 24. PMID: 31872418.
110. De Luca C, Sgariglia R, Nacchio M, Pisapia P, Migliatico I, Clery E, Gragnano G, Campione S, Vigliar E, Malapelle U, De Dominicis G, Bellevicine C, Troncone G. Rapid On-site Molecular Evaluation in thyroid cytopathology: A same-day cytological and molecular diagnosis. Diagn Cytopathol. 2020 Apr;48(4):300-307. doi: 10.1002/dc.24378. Epub 2020 Jan 6. PMID: 31904908.
111. Passiglia F, Pilotto S, Facchinetti F, Bertolaccini L, Del Re M, Ferrara R, Franchina T, Malapelle U, Menis J, Passaro A, Ramella S, Rossi G, Trisolini R, Novello S. Treatment of advanced non-small-cell lung cancer: The 2019 AIOM (Italian Association of Medical Oncology) clinical practice guidelines. Crit Rev Oncol Hematol. 2020 Feb;146:102858. doi: 10.1016/j.critrevonc.2019.102858. Epub 2019 Dec 28. PMID: 31918343.
112. Rocco D, Malapelle U, Del Re M, Della Gravara L, Pepe F, Danesi R, Troncone G, Gridelli C. Pharmacodynamics of current and emerging PD-1 and PD-L1 inhibitors for the treatment of non-small cell lung cancer. Expert Opin Drug Metab Toxicol. 2020 Feb;16(2):87-96. doi: 10.1080/17425255.2020.1721460. Epub 2020 Jan 30. PMID: 31978315.
113. Bessi S, Pepe F, Ottaviantonio M, Pisapia P, Malapelle U, Troncone G, Biancalani M. Comparison between two different next generation sequencing platforms for clinical relevant gene mutation test in solid tumours. J Clin Pathol. 2020 Sep;73(9):602-604. doi: 10.1136/jclinpath-2019-206422. Epub 2020 Feb 14. PMID: 32060075.
114. Passiglia F, Bertolaccini L, Del Re M, Facchinetti F, Ferrara R, Franchina T, Malapelle U, Menis J, Passaro A, Pilotto S, Ramella S, Rossi G, Trisolini R, Novello S. Diagnosis and treatment of early and locally advanced non-small-cell lung cancer: The 2019 AIOM (Italian Association of Medical Oncology) clinical practice guidelines. Crit Rev Oncol Hematol. 2020 Apr;148:102862. doi: 10.1016/j.critrevonc.2019.102862. Epub 2020 Jan 25. PMID: 32062311.
115. Malapelle U, Muscarella LA, Pisapia P, Rossi A. Targeting emerging molecular alterations in the treatment of non-small cell lung cancer: current challenges and the way forward. Expert Opin Investig Drugs. 2020 Apr;29(4):363-372. doi: 10.1080/13543784.2020.1732922. Epub 2020 Feb 26. PMID: 32073317.
116. Gristina V*, Malapelle U*, Galvano A, Pisapia P, Pepe F, Rolfo C, Tortorici S, Bazan V, Troncone G, Russo A. The significance of epidermal growth factor receptor uncommon mutations in non-small cell lung cancer: A systematic review and critical appraisal. Cancer Treat Rev. 2020 Apr;85:101994. doi: 10.1016/j.ctrv.2020.101994. Epub 2020 Feb 21. PMID: 32113081. (*equal contribution)
117. Pisapia P, Pepe F, Troncone G, Malapelle U*. Predictive biomarkers for molecular pathology in lung cancer. Biomark Med. 2020 Mar;14(4):253-257. doi: 10.2217/bmm-2019-0490. Epub 2020 Mar 3. PMID: 32125183. (*corresponding author)
118. Passaro A, Malapelle U, Attili I, de Marinis F. Overcoming resistance to osimertinib in non-small cell lung cancer: Hopes, doubts, and in-between. Cancer. 2020 Jun 1;126(11):2594-2596. doi: 10.1002/cncr.32810. Epub 2020 Mar 10. PMID: 32154916.
119. Malapelle U, Pepe F, Pisapia P, Sgariglia R, Nacchio M, De Luca C, Lacalamita R, Tommasi S, Pinto R, Palomba G, Palmieri G, Vacirca D, Barberis M, Bottillo I, Grammatico P, Grillo LR, Costa V, Smeraglio R, Bruzzese D, Troncone G. Harmonization of Next-Generation Sequencing Procedure in Italian Laboratories: A Multi-Institutional Evaluation of the SiRe® Panel. Front Oncol. 2020 Mar 11;10:236. doi: 10.3389/fonc.2020.00236. PMID: 32219061; PMCID: PMC7078327.
120. Vigliar E, Iaccarino A, Bruzzese D, Malapelle U, Bellevicine C, Troncone G. Cytology in the time of coronavirus disease (covid-19): an Italian perspective. J Clin Pathol. 2020 Apr 20:jclinpath-2020-206614. doi: 10.1136/jclinpath-2020-206614. Epub ahead of print. PMID: 32312717; PMCID: PMC7211103.
121. Clery E, Pisapia P, Migliatico I, Pepe F, De Luca C, Russo M, De Rosa F, Smeraglia F, Insabato L, Vigliar E, Malapelle U, Mariconda M, Gridelli C, Troncone G. Cytology meets next generation sequencing and liquid biopsy: A case of lung adenocarcinoma presenting as metastasis to the phalanx. Diagn Cytopathol. 2020 Aug;48(8):759-764. doi: 10.1002/dc.24438. Epub 2020 Apr 22. PMID: 32320137.
122. Vigliar E, Iaccarino A, Campione S, Campanino MR, Clery E, Pisapia P, De Luca C, Bellevicine C, Malapelle U, De Dominicis G, Troncone G. PD-L1 expression in cell-blocks of non-small cell lung cancer: The impact of prolonged fixation. Diagn Cytopathol. 2020 Jul;48(7):595-603. doi: 10.1002/dc.24439. Epub 2020 Apr 25. PMID: 32333728.
123. Malapelle U, Pepe F, Pisapia P, Loperto I, Scamardo MS, Egidio R, De Pascale T, De Vita A, Triassi M, Troncone G, Rubba F. La biopsia liquida quale segnale di progressione tumorale nel carcinoma polmonare: potenziale di intervento in prevenzione terziaria [Liquid biopsy as indication of tumour progression in lung cancer: a potential intervention in tertiary prevention]. Epidemiol Prev. 2020 Jan-Feb;44(1):84-88. Italian. doi: 10.19191/EP20.1.A002. PMID: 32374118.
124. Rolfo C, Cardona AF, Cristofanilli M, Paz-Ares L, Diaz Mochon JJ, Duran I, Raez LE, Russo A, Lorente JA, Malapelle U, Gil-Bazo I, Jantus-Lewintre E, Pauwels P, Mok T, Serrano MJ; ISLB. Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB). Crit Rev Oncol Hematol. 2020 Jul;151:102978. doi: 10.1016/j.critrevonc.2020.102978. Epub 2020 May 5. Erratum in: Crit Rev Oncol Hematol. 2020 Aug 18;154:103058. PMID: 32428812.
125. Malapelle U, De Luca C, Iaccarino A, Pepe F, Pisapia P, Russo M, Sgariglia R, Nacchio M, Vigliar E, Bellevicine C, Schmitt FC, Troncone G. Predictive molecular pathology in the time of COVID-19. J Clin Pathol. 2020 May 19:jclinpath-2020-206711. doi: 10.1136/jclinpath-2020-206711. Epub ahead of print. PMID: 32434770; PMCID: PMC7242869.
126. Belardinilli F, Capalbo C, Malapelle U, Pisapia P, Raimondo D, Milanetti E, Yasaman M, Liccardi C, Paci P, Sibilio P, Pepe F, Bonfiglio C, Mezi S, Magri V, Coppa A, Nicolussi A, Gradilone A, Petroni M, Di Giulio S, Fabretti F, Infante P, Coni S, Canettieri G, Troncone G, Giannini G. Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer. Front Oncol. 2020 May 7;10:560. doi: 10.3389/fonc.2020.00560. PMID: 32457828; PMCID: PMC7221020.
127. Frisone D, Friedlaender A, Malapelle U, Banna G, Addeo A. A BRAF new world. Crit Rev Oncol Hematol. 2020 Aug;152:103008. doi: 10.1016/j.critrevonc.2020.103008. Epub 2020 May 26. PMID: 32485528.
128. Fusco N, Sajjadi E, Venetis K, Gaudioso G, Lopez G, Corti C, Rocco EG, Criscitiello C, Malapelle U, Invernizzi M. PTEN Alterations and Their Role in Cancer Management: Are We Making Headway on Precision Medicine? Genes (Basel). 2020 Jun 28;11(7):719. doi: 10.3390/genes11070719. PMID: 32605290; PMCID: PMC7397204.
129. Pagni F*, Malapelle U*, Doglioni C, Fontanini G, Fraggetta F, Graziano P, Marchetti A, Guerini Rocco E, Pisapia P, Vigliar EV, Buttitta F, Jaconi M, Fusco N, Barberis M, Troncone G. Digital Pathology and PD-L1 Testing in Non Small Cell Lung Cancer: A Workshop Record. Cancers (Basel). 2020 Jul 5;12(7):1800. doi: 10.3390/cancers12071800. PMID: 32635634; PMCID: PMC7408471. (*equal contribution)
130. Nikiforova MN, Lepe M, Tolino LA, Miller ME, Ohori NP, Wald AI, Landau MS, Kaya C, Malapelle U, Bellevicine C, Troncone G, Nikiforov YE, Baloch Z. Thyroid cytology smear slides: An untapped resource for ThyroSeq testing. Cancer Cytopathol. 2020 Jul 22. doi: 10.1002/cncy.22331. Epub ahead of print. PMID: 32697051.
131. Malapelle U, Pisapia P, Iaccarino A, Barberis M, Bellevicine C, Brunnström H, de Biase D, De Maglio G, Ericson Lindquist K, Fassan M, Fontanini G, Gruppioni E, Hofman P, Merkelbach-Bruse S, Molina Vila MA, Pujals A, Rapa I, Righi L, Rosell R, Schildgen O, Schildgen V, Schmitt FC, Tallini G, Vander Borght S, Vigliar E, Volante M, Wagener-Ryczek S, Weynand B, Troncone G. Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe. J Clin Pathol. 2020 Jul 31:jclinpath-2020-206957. doi: 10.1136/jclinpath-2020-206957. Epub ahead of print. PMID: 32737190; PMCID: PMC7397978.
132. Passiglia F*, Malapelle U*, Del Re M, Righi L, Pagni F, Furlan D, Danesi R, Troncone G, Novello S. KRAS inhibition in non-small cell lung cancer: Past failures, new findings and upcoming challenges. Eur J Cancer. 2020 Sep;137:57-68. doi: 10.1016/j.ejca.2020.06.023. Epub 2020 Jul 31. PMID: 32745965. (*equal contribution)
133. Nacchio M, Sgariglia R, Gristina V, Pisapia P, Pepe F, De Luca C, Migliatico I, Clery E, Greco L, Vigliar E, Bellevicine C, Russo A, Troncone G, Malapelle U. KRAS mutations testing in non-small cell lung cancer: the role of Liquid biopsy in the basal setting. J Thorac Dis. 2020 Jul;12(7):3836-3843. doi: 10.21037/jtd.2020.01.19. PMID: 32802465; PMCID: PMC7399406.
134. Rolfo C, Cardona AF, Cristofanilli M, Paz-Ares L, Diaz Mochon JJ, Duran I, Raez LE, Russo A, Lorente JA, Malapelle U, Gil-Bazo I, Jantus-Lewintre E, Pauwels P, Mok T, Serrano MJ; ISLB. Corrigendum to "Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)" [Crit. Rev. Oncol. Hematol. 151 (July) (2020) 102978]. Crit Rev Oncol Hematol. 2020 Aug 18;154:103058. doi: 10.1016/j.critrevonc.2020.103058. Epub ahead of print. Erratum for: Crit Rev Oncol Hematol. 2020 Jul;151:102978. PMID: 32823147.
135. Vigliar E, Iaccarino A, Sciortino M, De Luca C, Malapelle U, Bellevicine C, Troncone G. Molecular predictive testing in precision oncology: The Italian experience. Cancer Cytopathol. 2020 Sep;128(9):622-628. doi: 10.1002/cncy.22290. PMID: 32885914.
136. Malapelle U, Parente P, Pepe F, De Luca C, Cerino P, Covelli C, Balestrieri M, Russo G, Bonfitto A, Pisapia P, Fiordelisi F, D'Armiento M, Bruzzese D, Loupakis F, Pietrantonio F, Triassi M, Fassan M, Troncone G, Graziano P. Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study. Cells. 2020 Sep 2;9(9):E2019. doi: 10.3390/cells9092019. PMID: 32887373.
137. Malapelle U, Vigliar E, Troncone G. Biomarkers predictive value in early stage non-small cell lung cancer. Transl Lung Cancer Res. 2020 Aug;9(4):956-959. doi: 10.21037/tlcr.2020.04.16. PMID: 32953474; PMCID: PMC7481621.
138. Reale ML, Bironzo P, Bertaglia V, Palesandro E, Leone G, Tabbò F, Bungaro M, Audisio M, Mariniello A, Rapetti SG, Di Stefano RF, Artusio E, Capelletto E, Sperone P, Boccuzzi A, Calandri M, Perboni A, Malapelle U, Passiglia F, Novello S. SARS-CoV-2 Infection in Cancer Patients: A Picture of an Italian Onco-Covid Unit. Front Oncol. 2020 Aug 19;10:1722. doi: 10.3389/fonc.2020.01722. PMID: 32974210; PMCID: PMC7466731.
139. Fumagalli C, Guerini-Rocco E, Buttitta F, Iapicca P, You W, Mauri M, Felicioni L, Troncone G, Malapelle U, Scarpa A, Zamboni G, Calistri D, Barberis M, Marchetti A. Reliability and reproducibility among different platforms for tumour BRCA testing in ovarian cancer: a study of the Italian NGS Network. J Clin Pathol. 2020 Oct 5:jclinpath-2020-206800. doi: 10.1136/jclinpath-2020-206800. Epub ahead of print. PMID: 33020174.
140. Serrano MJ, Garrido-Navas MC, Diaz Mochon JJ, Cristofanilli M, Gil-Bazo I, Pauwels P, Malapelle U, Russo A, Lorente JA, Ruiz-Rodriguez AJ, Paz-Ares LG, Vilar E, Raez LE, Cardona AF, Rolfo C; International Society of Liquid Biopsy. Precision Prevention and Cancer Interception: The New Challenges of Liquid Biopsy. Cancer Discov. 2020 Nov;10(11):1635-1644. doi: 10.1158/2159-8290.CD-20-0466. Epub 2020 Oct 9. PMID: 33037026.
141. Malapelle U, Rossi G, Pisapia P, Barberis M, Buttitta F, Castiglione F, Cecere FL, Grimaldi AM, Iaccarino A, Marchetti A, Massi D, Medicina D, Mele F, Minari R, Orlando E, Pagni F, Palmieri G, Righi L, Russo A, Tommasi S, Vermi W, Troncone G. BRAF as a positive predictive biomarker: Focus on lung cancer and melanoma patients. Crit Rev Oncol Hematol. 2020 Oct 3;156:103118. doi: 10.1016/j.critrevonc.2020.103118. Epub ahead of print. PMID: 33038627.
142. Passaro A*, Malapelle U*, Del Re M, Attili I, Russo A, Guerini-Rocco E, Fumagalli C, Pisapia P, Pepe F, De Luca C, Cucchiara F, Troncone G, Danesi R, Spaggiari L, De Marinis F, Rolfo C. Understanding EGFR heterogeneity in lung cancer. ESMO Open. 2020 Oct;5(5):e000919. doi: 10.1136/esmoopen-2020-000919. PMID: 33067323; PMCID: PMC7569934. (*equal contribution)
143. Vigliar E, Cepurnaite R, Alcaraz-Mateos E, Ali SZ, Baloch ZW, Bellevicine C, Bongiovanni M, Botsun P, Bruzzese D, Bubendorf L, Büttner R, Canberk S, Capitanio A, Casadio C, Cazacu E, Cochand-Priollet B, D'Amuri A, Eloy C, Engels M, Fadda G, Fontanini G, Fulciniti F, Hofman P, Iaccarino A, Ieni A, Jiang XS, Kakudo K, Kern I, Kholova I, Liu C, Lobo A, Lozano MD, Malapelle U, Maleki Z, Michelow P, Musayev J, Özgün G, Oznur M, Peiró Marqués FM, Pisapia P, Poller D, Pyzlak M, Robinson B, Rossi ED, Roy-Chowdhuri S, Saieg M, Savic Prince S, Schmitt FC, Javier Seguí Iváñez F, Štoos-Veić T, Sulaieva O, Sweeney BJ, Tuccari G, van Velthuysen ML, VanderLaan PA, Vielh P, Viola P, Voorham R, Weynand B, Zeppa P, Faquin WC, Pitman MB, Troncone G. Global impact of the COVID-19 pandemic on cytopathology practice: Results from an international survey of laboratories in 23 countries. Cancer Cytopathol. 2020 Oct 27. doi: 10.1002/cncy.22373. Epub ahead of print. PMID: 33108683.
144. Pisapia P, Malapelle U, Salatiello M, Rosell R, Troncone G. A narrative review of lung cancer cytology in the times of coronavirus: what physicians should know. Transl Lung Cancer Res. 2020 Oct;9(5):2074-2081. doi: 10.21037/tlcr-20-795. PMID: 33209627; PMCID: PMC7653120.
145. de Biase D, Fassan M, Malapelle U*. Next-Generation Sequencing in Tumor Diagnosis and Treatment. Diagnostics (Basel). 2020 Nov 17;10(11):962. doi: 10.3390/diagnostics10110962. PMID: 33212911; PMCID: PMC7698429. (* corresponding author)
146. Pisapia P, Pepe F, Iaccarino A, Sgariglia R, Nacchio M, Russo G, Gragnano G, Malapelle U, Troncone G. BRAF: A Two-Faced Janus. Cells. 2020 Nov 27;9(12):E2549. doi: 10.3390/cells9122549. PMID: 33260892.
147. Iaccarino A, Pisapia P, Pepe F, Sgariglia R, Nacchio M, Russo G, Gragnano G, De Luca C, Troncone G, Malapelle U. Liquid biopsy for BRAF mutations testing in non-small cell lung cancer: a retrospective study. J Clin Pathol. 2020 Dec 4:jclinpath-2020-207107. doi: 10.1136/jclinpath-2020-207107. Epub ahead of print. PMID: 33277344.
148. Palladino R, Migliatico I, Sgariglia R, Nacchio M, Iaccarino A, Malapelle U, Vigliar E, Salvatore D, Troncone G, Bellevicine C. Thyroid fine-needle aspiration trends before, during, and after the lockdown: what we have learned so far from the COVID-19 pandemic. Endocrine. 2020 Dec 7:1–6. doi: 10.1007/s12020-020-02559-z. Epub ahead of print. PMID: 33284396; PMCID: PMC7719849.
149. Sabbatino F, Liguori L, Malapelle U, Schiavi F, Tortora V, Conti V, Filippelli A, Tortora G, Ferrone CR, Pepe S. Case Report: BAP1 Mutation and RAD21 Amplification as Predictive Biomarkers to PARP Inhibitor in Metastatic Intrahepatic Cholangiocarcinoma. Front Oncol. 2020 Nov 27;10:567289. doi: 10.3389/fonc.2020.567289. PMID: 33330039; PMCID: PMC7728995.
150. Pepe F, Pisapia P, Gristina V, Rocco D, Micheli M, Micheli P, Iaccarino A, Tufano R, Gragnano G, Russo G, De Luca C, Sgariglia R, Nacchio M, Girolami I, Eccher A, Russo A, Troncone G, Malapelle U. Tumor mutational burden on cytological samples: A pilot study. Cancer Cytopathol. 2020 Dec 30. doi: 10.1002/cncy.22400. Epub ahead of print. PMID: 33378102.
151. De Luca C, Pepe F, Iaccarino A, Pisapia P, Righi L, Listì A, Greco L, Gragnano G, Campione S, De Dominicis G, Pagni F, Sgariglia R, Nacchio M, Tufano R, Conticelli F, Vigliar E, Bellevicine C, Cortinovis DL, Novello S, Molina-Vila MA, Rosell R, Troncone G, Malapelle U. RNA-Based Assay for Next-Generation Sequencing of Clinically Relevant Gene Fusions in Non-Small Cell Lung Cancer. Cancers (Basel). 2021 Jan 4;13(1):139. doi: 10.3390/cancers13010139. PMID: 33406752; PMCID: PMC7796105.
152. Vavala T, Malapelle U, Veggiani C, Ludovini V, Papotti M, Leone A, Graziano P, Minari R, Bono F, Sapino A, Manotti L, Troncone G, Pisapia P, Girlando S, Buffoni L, Righi L, Colantonio I, Bertetto O, Novello S. Molecular profiling of advanced non-small cell lung cancer in the era of immunotherapy approach: a multicenter Italian observational prospective study of biomarker screening in daily clinical practice. J Clin Pathol. 2021 Jan 28:jclinpath-2020-207339. doi: 10.1136/jclinpath-2020-207339. Epub ahead of print. PMID: 33509945.
153. Malapelle U, Passiglia F, Cremolini C, Reale ML, Pepe F, Pisapia P, Avallone A, Cortinovis D, De Stefano A, Fassan M, Fontanini G, Galetta D, Lauricella C, Listì A, Loupakis F, Pagni F, Pietrantonio F, Pilotto S, Righi L, Bianchi AS, Parra HS, Tiseo M, Verzè M, Troncone G, Novello S. RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients. Eur J Cancer. 2021 Feb 12;146:74-83. doi: 10.1016/j.ejca.2021.01.015. Epub ahead of print. PMID: 33588147.
154. Vigliar E, Cepurnaite R, Iaccarino A, Pisapia P, De Luca C, Malapelle U, Bellevicine C, Troncone G. Cytopathology practice during the COVID-19 postlockdown: An Italian experience. Cancer Cytopathol. 2021 Feb 17. doi: 10.1002/cncy.22416. Epub ahead of print. PMID: 33595924.
155. Pisapia P, Pepe F, Iaccarino A, Sgariglia R, Nacchio M, Conticelli F, Salatiello M, Tufano R, Russo G, Gragnano G, Girolami I, Eccher A, Malapelle U, Troncone G. Next Generation Sequencing in Cytopathology: Focus on Non-Small Cell Lung Cancer. Front Med (Lausanne). 2021 Feb 11;8:633923. doi: 10.3389/fmed.2021.633923. PMID: 33644101; PMCID: PMC7904874.
156. Gragnano G, Nacchio M, Sgariglia R, Conticelli F, Iaccarino A, De Luca C, Troncone G, Malapelle U. Performance evaluation of a fully closed real-time PCR platform for the detection of KRAS p.G12C mutations in liquid biopsy of patients with non-small cell lung cancer. J Clin Pathol. 2021 Mar 1:jclinpath-2021-207416. doi: 10.1136/jclinpath-2021-207416. Epub ahead of print. PMID: 33649142.
157. Angerilli V, Galuppini F, Pagni F, Fusco N, Malapelle U, Fassan M. The Role of the Pathologist in the Next-Generation Era of Tumor Molecular Characterization. Diagnostics (Basel). 2021 Feb 18;11(2):339. doi: 10.3390/diagnostics11020339. PMID: 33670699; PMCID: PMC7922586.
158. Kerr KM, Bibeau F, Thunnissen E, Botling J, Ryška A, Wolf J, Öhrling K, Burdon P, Malapelle U, Büttner R. The evolving landscape of biomarker testing for non-small cell lung cancer in Europe. Lung Cancer. 2021 Feb 22;154:161-175. doi: 10.1016/j.lungcan.2021.02.026. Epub ahead of print. PMID: 33690091.
159. Malapelle U, Pilotto S, Passiglia F, Pepe F, Pisapia P, Righi L, Listì A, Bironzo P, Belluomini L, Tabbò F, Reale ML, Russo G, De Luca C, Novello S, Troncone G. Dealing with NSCLC EGFR mutation testing and treatment: A comprehensive review with an Italian real-world perspective. Crit Rev Oncol Hematol. 2021 Mar 17;160:103300. doi: 10.1016/j.critrevonc.2021.103300. Epub ahead of print. PMID: 33744362.
160. Malapelle U, Pepe F, Pisapia P, Sgariglia R, Nacchio M, Barberis M, Bilh M, Bubendorf L, Büttner R, Cabibi D, Castiglia M, De Andrea CE, de Biase D, Dumur CI, Fontanini G, Freire J, Gristina V, Hofman P, Ilie M, Lozano MD, Merkelbach-Bruse S, Pappesch R, Pelusi N, Roma G, Russo A, Savic S, Siemanowski J, Tallini G, Tischler V, Vander Borght S, Weynand B, Xu T, Troncone G. TargetPlex FFPE-Direct DNA Library Preparation Kit for SiRe NGS panel: an international performance evaluation study. J Clin Pathol. 2021 Mar 25:jclinpath-2021-207450. doi: 10.1136/jclinpath-2021-207450. Epub ahead of print. PMID: 33766954.
161. Pisapia P, Costa JL, Pepe F, Russo G, Gragnano G, Russo A, Iaccarino A, de Miguel-Perez D, Serrano MJ, Denninghoff V, Quagliata L, Rolfo C, Malapelle U*. Next Generation Sequencing for liquid biopsy based testing in Non-Small Cell Lung Cancer in 2021. Crit Rev Oncol Hematol. 2021 Mar 26:103311. doi: 10.1016/j.critrevonc.2021.103311. Epub ahead of print. PMID: 33781866.(*corresponding author).
162. Sgariglia R, Nacchio M, Migliatico I, Vigliar E, Malapelle U, Pisapia P, De Luca C, Iaccarino A, Salvatore D, Masone S, Troncone G, Bellevicine C. Moving towards a local testing solution for undetermined thyroid fine-needle aspirates: validation of a novel custom DNA-based NGS panel. J Clin Pathol. 2021 Mar 31:jclinpath-2021-207429. doi: 10.1136/jclinpath-2021-207429. Epub ahead of print. PMID: 33789920.
163. Pisapia P, Pepe F, Sgariglia R, Nacchio M, Russo G, Conticelli F, Girolami I, Eccher A, Bellevicine C, Vigliar E, Malapelle U, Troncone G. Next generation sequencing in cytology. Cytopathology. 2021 Apr 1. doi: 10.1111/cyt.12974. Epub ahead of print. PMID: 33792981.
164. Addeo A, Passaro A, Malapelle U, Luigi Banna G, Subbiah V, Friedlaender A. Immunotherapy in non-small cell lung cancer harbouring driver mutations. Cancer Treat Rev. 2021 Mar 19;96:102179. doi: 10.1016/j.ctrv.2021.102179. Epub ahead of print. PMID: 33798954.
165. Rebuzzi SE, Zullo L, Rossi G, Grassi M, Murianni V, Tagliamento M, Prelaj A, Coco S, Longo L, Dal Bello MG, Alama A, Dellepiane C, Bennicelli E, Malapelle U, Genova C. Novel Emerging Molecular Targets in Non-Small Cell Lung Cancer. Int J Mol Sci. 2021 Mar 5;22(5):2625. doi: 10.3390/ijms22052625. PMID: 33807876.
166. de Biase D*, Malapelle U*, De Leo A, Maloberti T, Visani M, Pisapia P, Acquaviva G, Pepe F, Russo G, Iaccarino A, Pession A, Tallini G, Troncone G. Multi-gene custom panels for the characterisation of metastatic colorectal carcinoma in clinical practice: express the role of PIK3CA mutations. J Clin Pathol. 2021 Apr 5:jclinpath-2021-207468. doi: 10.1136/jclinpath-2021-207468. Epub ahead of print. PMID: 33820865.(* contributed equally and corresponding authors)
167. De Luca C, Gragnano G, Conticelli F, Cennamo M, Pisapia P, Terracciano D, Malapelle U, Montella E, Triassi M, Troncone G, Portella G. Evaluation of a fully closed real time PCR platform for the detection of SARS-CoV-2 in nasopharyngeal swabs: a pilot study. J Clin Pathol. 2021 Apr 9:jclinpath-2021-207516. doi: 10.1136/jclinpath-2021-207516. Epub ahead of print. PMID: 33837109; PMCID: PMC8042579.
168. Fusco N*, Malapelle U*, Fassan M, Marchiò C, Buglioni S, Zupo S, Criscitiello C, Vigneri P, Dei Tos AP, Maiorano E, Viale G. PIK3CA Mutations as a Molecular Target for Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer. Front Oncol. 2021 Mar 25;11:644737. doi: 10.3389/fonc.2021.644737. PMID: 33842357; PMCID: PMC8027489.(*contributed equally).
169. Denninghoff V, Russo A, de Miguel-Pérez D, Malapelle U, Benyounes A, Gittens A, Cardona AF, Rolfo C. Small Cell Lung Cancer: State of the Art of the Molecular and Genetic Landscape and Novel Perspective. Cancers (Basel). 2021 Apr 6;13(7):1723. doi: 10.3390/cancers13071723. PMID: 33917282; PMCID: PMC8038650.
170. Galvano A, Gristina V, Malapelle U, Pisapia P, Pepe F, Barraco N, Castiglia M, Perez A, Rolfo C, Troncone G, Russo A, Bazan V. The prognostic impact of tumor mutational burden (TMB) in the first-line management of advanced non-oncogene addicted non-small-cell lung cancer (NSCLC): a systematic review and meta-analysis of randomized controlled trials. ESMO Open. 2021 Apr 30;6(3):100124. doi: 10.1016/j.esmoop.2021.100124. Epub ahead of print. PMID: 33940346.
171. Iaccarino A, Salatiello M, Migliatico I, De Luca C, Gragnano G, Russo M, Bellevicine C, Malapelle U, Troncone G, Vigliar E. PD-L1 and beyond: Immuno-oncology in cytopathology. Cytopathology. 2021 May 6. doi: 10.1111/cyt.12982. Epub ahead of print. PMID: 33955097.

Book chapters:
1. Pisapia P, Malapelle U, Troncone G. (2017). Clinical Practice Implications: Monitoring Drug Response and Resistance. Liquid Biopsy in Cancer Patients, pp 201-202, Springer.
2. Bellevicine C, Malapelle U, Vigliar E, Pisapia P, Ruosi C, Troncone G. (2018). How to Prepare Cytological Samples for Molecular Testing. Molecular Applications in Cytology, pp 11-28, Springer.
3. Malapelle U, Ricciuti B, Baglivo S, Pepe F, Pisapia P, Anastasi P, Tazza M, Sidoni A, Liberati AM, Bellezza G, Chiari R, Metro G. (2018). Osimertinib. Small Molecules in Oncology, Third Edition, pp 257-276. Springer.
4. Malapelle U, Pisapia P, Passiglia F, Dendooven A, Pauwels P, Salgado R, Rolfo C. (2019). Next-Generation Sequencing in Clinical Practice. Oncogenomics, pp 57-64. Academic Press.
5. Malapelle U, Pisapia P, Cieri M, Pepe F, Troncone G. (2019). RNA-Based Assays. Molecular Diagnostics in Cytopathology, pp 99-119. Springer, Cham.
6. Pisapia P, Cieri M, Pepe F, Malapelle U, Troncone G. (2019). DNA-Based Sequencing Assays. Molecular Diagnostics in Cytopathology, pp 83-97. Springer, Cham.

Major Invited Speeches:
 1: “Congresso Annuale di Anatomia Patologica SIAPEC-IAP”, 25-27 September 2008, Bari, Italy
 2: “22nd European Congress of Pathology”, 04-09 September 2009, Florence, Italy.
 3: “Congresso Annuale di Anatomia Patologica SIAPEC-IAP”, 21-25 September 2010, Bologna, Italy.
 4: “Molecular Cytopathology”, 04 October 2010, Naples, Italy.
 5: "Il ruolo della targeted therapy nelle neoplasie che iperesprimono EGFR'', 14 October 2011, IRCCS-CROB, Rionero in Vulture, Italy.
 6: "Congresso Annuale di Anatomia Patologica SIAPEC - IAP'', 27-29 October 2011, Palermo, Italy.
 7: "I Congresso nazionale di Citopatologia SIAPEC - IAP", 30 June 2012, Trieste, Italy.
 8: "III Molecular Cytopathology", 27 September 2012, Naples, Italy.
 9: "GIST & TUMORI RARI", 28 February 2014, Naples, Italy.
 10: "IV Corso Nazionale AIOM - SIAPEC, Percorso e metodologia nella diagnostica molecolare in oncologia", 26 March 2014, Rome, Italy.
 11: "ESHO 2014 International Conference", 11-14 June 2014, Turin, Italy.
 12: “III Congresso Associazione Giovani Oncologi Campani - Update sul trattamento del tumore del colon e del retto", 10 October 2014, Naples, Italy.
 13: “Congresso Annuale di Anatomia Patologica SIAPEC-IAP”, 22-25 October 2014, Florence, Italy.
 14: "Nuove evidenze nella gestione del carcinoma del colon metastatico", 17 December 2014, Pozzuoli, Italy.
 15: "Principali evidenze e punti aperti nel trattamento di II linea dell'adenocarcinoma in stadio avanzato", 23 January 2015, Milan, Italy.
 16: "Il confine tra benigno e maligno: il percorso diagnostico dalla morfologia alla biologia molecolare", 28-30 January 2015, Naples, Italy.
 17: "Il laboratorio di Patologia Molecolare: quale presente e quale futuro", 26-27 February 2015, Naples, Italy.
 18: "Metodologie di Anatomia Patologica per lo studio di Biomarcatori predittivi di risposta terapeutica", 9 April 2015, Naples, Italy.
 19: "Strategie terapeutiche nel carcinoma del colon - retto metastatico", 28 April 2015, Naples, Italy.
 20: "Primo incontro nazionale del gruppo di Patologia Molecolare e Medicina Predittiva (PMMP)", 20 June 2015, Rome, Italy.
 21: "Il patologo ed i test diagnostici di laboratorio: l'importanza della preclinica", 23 June 2015, Naples, Italy.
 22: "Campus in Oncologia", 25-26 June 2015, Bologna, Italy.
 23: "Strategie terapeutiche in prima e seconda linea per i pazienti con NSCLC EGFR+ e EGFR WT", 11 September 2015, Avellino, Italy.
 24: "39th European Congress of Cytology", 20-23 September 2015, Milan, Italy.
 25: "Dalla Diagnosi morfologica alla biopsia liquida: la base per l'impostazione del percorso terapeutico", Congresso Nazionale AIOM, 23-25 October 2015, Rome, Italy.
 26: "L'approccio terapeutico al paziente con NSCLC tra esperienze acquisite e prospettive future", 2 Novermber 2015, Milan, Italy.
 27: "Dalle evidenze del IASLC al dibattito aperto sulle attuali opzioni terapeutiche disponibili", 4 November 2015, Aci Castello, Italy.
 28: "Detectin Acquired Resistance on Liquid Biopsy", 10 November 2015, Naples, Italy.
 29: "RAS master program", 11 November 2015, Naples, Italy.
 30: "L'approccio terapeutico al paziente con NSCLC tra esperienze acquisite e prospettive future", 12 November 2015, Rome, Italy.
 31: "L'approccio terapeutico al paziente con NSCLC tra esperienze acquisite e prospettive future", 23 November 2015, Naples, Italy.
 32: "Scientific Exchange meeting oncology on lung cancer", 1-2 December 2015, Milan, Italy.
 33: "ALKUANTO: dall'importanza della determinazione di ALK all'importanza della gestione terapeutica appropriata", 18 March 2016, Naples, Italy.
 34: "Marcatori Molecolari in Anatomia Patologica: quando, come e perchè", 8 April 2016, University Maggiore della Carità, Novara, Italy.
 35: “NSCLC: what has changed?", 6 May 2016, Forte dei Marmi, Italy.
 36: "La chemioterapia e le terapie target nell'era dell'immunoterapia", 20 May 2016, Serravalle Scrivia, Italy.
 37: "Terapie a bersaglio molecolare nel carcinoma del polmone. Monitoraggio molecolare: come, quando e perchè?, 26 May 2016, Spedali Civili di Brescia, Brescia, Italy.
 38: "II Incontro Nazionale del gruppo italiano di Patologia Molcolare e Medicina Predittiva", 31 May 2016, Bologna, Italy.
 39: “Privat meet. ASCO annual meeting 2016", 3-7 June 2016, Chicago, IL, USA.
 40: "Il carcinoma del colon-retto metastatico: strategie di trattamento attuali e future.”, 22 June 2016, Naples, Italy.
 41: "I congresso regionale FONICAP", 1 July 2016, Cagliari, Italy.
 42: "Next generation network: from the knoledge to know – how. focus on liquid biopsy”, 29 September 2016, Rome, Italy.
 43: "Liquid biopsy in NSCLC clinical practice", 30 September 2016, Università Piemonte Orientale, Novara, Italy.
 44: “Private meet on NSCLC. ESMO 2016”, 7-11 October 2016, Copenhagen, Denmark.
 45: "Microambiente tumorale. Antiangiogenici e immunoterapia: miti e realtà", 11 October 2016, Milan, Italy.
 46: "V Molecular Cytopathology", 18 October 2016, Naples, Italy.
 47: "FOCUS on Neoplasie e nuove terapie", 20 October 2016, Lucca, Italy.
 48: "Strategie di trattamento nel NSCLC in stadio avanzato", 21 October 2016, Bologna, Italy.
 49: "Oncologia molecolare del polmone - consenso informato e responsabilità professionale", 8 November 2016, Naples, Italy.
 50: "Il carcinoma del colon retto metastatico: strategie di trattamento attuali e future", 9 November 2016, Naples, Italy.
 51: "Nuove frontiere diagnostico terapeutiche nelle neoplasie polmonari, renali e nel melanoma", 12 November 2016, Novara, Italy.
 52: "Ulisse: finding the way in lung cancer", 22-23 November 2016, Rome, Italy.
 53: "Higliths in oncologia: il trattamento del carcinoma colorettale metastatico ras wild - type", 26 November 2016, Rende, Italy.
 54: "Ulisse: finding the way in lung cancer", 29 November 2016, Naples, Italy.
 55: "Novità nei tumori polmonari", 30 November 2016, Bolzano, Italy.
 56: "PD-L1 un riferimento emergente nelle strategie dell'immunoncologia", 6 December 2016, Naples, Italy.
 57: "BEST OF WLCC 2016", Florence, Italy, after “World Lung Cancer Conference 2016", 13 December 2016, Wien, Austria.
 58: "Le patologie emergenti, confronto interdisciplinare NSCLC EGFR+ VE: how the multidisciplinary approach wins the game", 16 December 2016, Monza, Italy.
 59: "Master class mCRC2 2017", 7-8 April 2017, Baveno, Italy.
 60: “Stand Alone Scientific Symposium CTIO: Focus on Lung Cancer”, 18-19 April 2017, Rome, Italy.
 61: "IO YOUNG: una nuova prospettiva per l'immunoterapia", 12-13 May 2017, Milan, Italy.
 62: "PD-L1: un riferimento emergente nell'immuno - oncologia", 15 May 2017, Turin, Italy.
 63: “Next Generation Technologies – simultaneous biomarkers evaluation in clinical practice”, 31 May 2015, Naples, Italy.
 64: "III Incontro Nazionale del gruppo italiano di Patologia Molcolare e Medicina Predittiva", 6 June 2017, Bologna, Italy.
 65: “Congresso Nazionale dell’Associazione Italiana di Pneumologia Oncologica – AIPO – 2017”, 10-11 June 2017, Florence, Italy.
 66: “La selezione del paziente NSCLC”, 16 June 2017, Agrigento, Italy.
 67: “Tavola rotonda sul trattamento del paziente con NSCLC.”, 22 June 2017, Cagliari, Italy.
 68: “Win symposium + meet the expert”, 25-27 June 2017, Paris, France.
 69: “European Thoracic Oncology Platform”, 5-8 October 2017, Amsterdam, Netherlands.
 70: “Congresso Annuale di Anatomia Patologica SIAPEC-IAP”, 12-14 October 2017, Naples, Italy.
 71: “Congresso Nazionale della Associazione Italiana di Oncologia Medica – AIOM”, 27-29 October 2017, Rome, Italy.
 72: “Next Generation Sequencing to Next Generation Oncologist”, 20 November 2017, Istituto Mario Negri, Milan, Italy.
 73: “VI Molecular Cytopathology”, 4 December 2017, Naples, Italy.
 74: "Next generation network: from the knoledge to know – how. focus on liquid biopsy”, 11 December 2017, Naples, Italy.
 75: “Oltre la 1^ linea: il percorso terapeutico del paziente con mRCC”, 19 December 2017, Naples, Italy.
 76: “IPF Connect 2.0”, 1 February 2018, Catania, Italy.
 77: “IX Molecular Cytopathology”, 4 December 2020, Naples, Italy.
 78: Hot Topic Liquid Biopsy IASLC, Worldwide wirtual event, 2 -3 October 2020.
 79: 16º CONGRESO URUGUAYO DE ONCOLOGIA, 18 November 2020 (web – based congress), Montevideo, Uruguay.
 SOHC 2020, National Switzerland Congress of Oncology and Hematology, (we – based congress) Geneva, Switzerland.
 European Congress of Pathology 2020, Thermo Fisher Scientific – Symposium, web based congress, 7 December 2020.
 Focus on uncommon EGFR mutations in NSCLC: for pathologists. 16 and 23 March 2021.



Awards:
2009: Best Cytopathology Study Award, 22nd European Congress of Pathology, Florence, Italy.
2021: Frontiers in Oncology - GYN Associate Editorial Recognition Award.

Scopus
Number of citations: 2411.
H-index: 27.

Google Scholar
Number of citations: 3146.
H-index: 31.

I authorize the processing of personal data contained in my curriculum vitae on the basis of art. 13 of Legislative Decree 196/2003 and art. 13 GDPR 679/16 “European regulation on the protection of personal data”.

19 May 2021

Umberto Malapelle