Research activities of Dott. Salvatore Raffa, Researcher of the Dept. of Clinical and Molecular Medicine of “Sapienza” University of Rome, are mostly devoted to the analysis of the cellular and tissue expression of receptors for epithelial growth factors and of their role in hyperproliferative and neoplastic processes.
In addition, research activity has been focused on: i) the maturation of Herpesvirus, in particular on the analysis of the intracellular localization and function of viral glycoproteins in infected or producing cells
ii) the study of role of mitochondrial structure-function pattern on cardio- cerebrovascular diseases and in breast cancer models;
iii) the application of confocal microscopy and transmission electron microscopy to ultrastructural pathology and histocytopathological diagnostics;
iv) the optimization of methods for the separation and characterization of disseminated and circulating tumor cells.