NOEMI SVOLACCHIA

Dottoressa di ricerca

ciclo: XXXV



Titolo della tesi: Molecular mechanisms controlling the relationship between cell expansion and cell differentiation

Plant cells are enclosed by a specialized type of extracellular matrix, the cell wall. Growing cells are surrounded by the primary cell wall which is composed by three different polysaccharides: cellulose microfibrils, hemicellulose and pectins. Cellulose and hemicellulose together are fundamental to provide strength and robustness to the cell wall while pectins create a gel-like structure that allows cell expansion. Changes in the cell wall composition determine modifications of its mechanical properties. Several studies indicate that besides its structural function, the cell wall is implicated in the regulation of morphogenesis and different aspects of plant development, while a specific control on cell state remains elusive. Here, using the Arabidopsis thaliana root apical meristem as model system and by means of a molecular-genetic approach, I demonstrate that the cell wall can control and modify cells activities. I was able to show that a stiffer cell wall induces cell division while an elastic cell wall promotes cell differentiation. Moreover, by using a transcriptomic analysis, in which cell wall mechanical properties are altered in a time-controlled and in a tissue-specific manner, I laid down the foundation to shed light on the genes that, by responding to changes in cell wall mechanical properties, trigger a change in cell activity.

Produzione scientifica

11573/1688737 - 2023 - microRNA165 and 166 modulate response of the Arabidopsis root apical meristem to salt stress
Scintu, Daria; Scacchi, Emanuele; Cazzaniga, Francesca; Vinciarelli, Federico; De Vivo, Mirko; Shtin, Margaryta; Svolacchia, Noemi; Bertolotti, Gaia; Unterholzner, Simon Josef; Del Bianco, Marta; Timmermans, Marja; Di Mambro, Riccardo; Vittorioso, Paola; Sabatini, Sabrina; Costantino, Paolo; Dello Ioio, Raffaele - 01a Articolo in rivista
rivista: COMMUNICATIONS BIOLOGY ([London]: Springer Nature) pp. - - issn: 2399-3642 - wos: WOS:001048568700001 (2) - scopus: 2-s2.0-85167740002 (1)

11573/1668591 - 2023 - The mutual inhibition between PLETHORAs and ARABIDOPSIS RESPONSE REGULATORs controls root zonation
Shtin, Margaryta; Polverari, Laura; Svolacchia, Noemi; Bertolotti, Gaia; Unterholzner, Simon J; Mambro, Riccardo Di; Costantino, Paolo; Ioio, Raffaele Dello; Sabatini, Sabrina - 01a Articolo in rivista
rivista: PLANT AND CELL PHYSIOLOGY (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. - - issn: 0032-0781 - wos: WOS:000932131300001 (2) - scopus: 2-s2.0-85150396530 (2)

11573/1668653 - 2023 - Cytokinins
Svolacchia, Noemi; Sabatini, Sabrina - 01g Articolo di rassegna (Review)
rivista: CURRENT BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. R10-R13 - issn: 0960-9822 - wos: WOS:000925836900001 (7) - scopus: 2-s2.0-85145700974 (6)

11573/1454974 - 2020 - A PHABULOSA-controlled genetic pathway regulates ground tissue patterning in the Arabidopsis root
Bertolotti, Gaia; Unterholzner, Simon Josef; Scintu, Daria; Salvi, Elena; Svolacchia, Noemi; Di Mambro, Riccardo; Ruta, Veronica; Linhares Scaglia, Francisco; Vittorioso, Paola; Sabatini, Sabrina; Costantino, Paolo; Dello Ioio, Raffaele - 01a Articolo in rivista
rivista: CURRENT BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. - - issn: 0960-9822 - wos: WOS:000631966000008 (14) - scopus: 2-s2.0-85097093740 (16)

11573/1460419 - 2020 - Arabidopsis primary root growth: let it grow, can't hold it back anymore!
Svolacchia, Noemi; Salvi, Elena; Sabatini, Sabrina - 01a Articolo in rivista
rivista: CURRENT OPINION IN PLANT BIOLOGY (Current Biology, London) pp. 133-141 - issn: 1369-5266 - wos: WOS:000600745300018 (11) - scopus: 2-s2.0-85092761327 (13)

11573/1275764 - 2019 - The Lateral Root Cap Acts as an Auxin Sink that Controls Meristem Size
Di Mambro, Riccardo; Svolacchia, Noemi; Dello Ioio, Raffaele; Pierdonati, Emanuela; Salvi, Elena; Pedrazzini, Emanuela; Vitale, Alessandro; Perilli, Serena; Sozzani, Rosangela; Benfey, Philip N; Busch, Wolfgang; Costantino, Paolo; Sabatini, Sabrina - 01a Articolo in rivista
rivista: CURRENT BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 1199-1205.e4 - issn: 0960-9822 - wos: WOS:000462931400028 (49) - scopus: 2-s2.0-85063388496 (53)

11573/1275762 - 2019 - Cytokinin-Dependent Control of GH3 Group II Family Genes in the Arabidopsis Root
Pierdonati, Emanuela; Unterholzner, Simon Josef; Salvi, Elena; Svolacchia, Noemi; Bertolotti, Gaia; Dello Ioio, Raffaele; Sabatini, Sabrina; Di Mambro, Riccardo - 01a Articolo in rivista
rivista: PLANTS (Basel: MDPI) pp. - - issn: 2223-7747 - wos: WOS:000467296200017 (28) - scopus: 2-s2.0-85065082661 (29)

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