MONICA BALLARINO
Dati Personali
Cittadinanza: Italiana
Website: https://corsidilaurea.uniroma1.it/it/users/monicaballarinouniroma1.it
Identificativi di ricerca
ORCID ID: 0000-0002-8595-7105
SCOPUS Author ID: 6603725001
Formazione/Qualifica
2017 Abilitazione Scientifica Nazionale (ASN) II Fascia. Eleggibilità a I Fascia. Disciplina Accademica: Biologia Molecolare (05/E2)
2005 PhD in Genetica e Biologia Molecolare, conseguito in Sapienza Università di Roma, Italia
2003 Abilitazione alla professione di Biologo (150/150)
2001 Laurea magistrale (LM-6) cum laude in Scienze Biologiche (indirizzo BIOMOLECOLARE), Sapienza Università di Roma, Italia
Attività di Ricerca ed esperienze Post-dottorato
2019-oggi Professore II fascia c/o Dip. Biologia e Biotecnologie Charles Darwin , BBCD, Sapienza Università di Roma, Italia
2016-19 Ricercatore RTDB c/o BBCD, SapienzaUniversità di Roma, Italia
2012-15 Ricercatore RTDA c/o BBCD, Sapienza Università di Roma, Italia
2009-12 Ricercatore associato presso il laboratorio del Prof. Laszlo Tora, IGBMC, CNRS/INSERM/Université de Strasbourg, Francia
2010 Visiting scientist c/o il laboratorio del Prof. Olivier Bensaude, Institut de Biologie de l ENS, Parigi, Francia
2005-09 Attività di Post-dottorato c/o il laboratorio della Prof. Irene Bozzoni, Dip. GBM, Sapienza Università di Roma, Italia
2002-05 PhD in Gen. e Biologia Molecolare, School of Molecular Medicine and Biology, Dip. GBM, Sapienza Università di Roma, Italia
Pubblicazioni su Riviste Peer-Reviewed Internazionali
Ballarino M, Pepe G, Helmer-Citterich M, Palma A. 2023 "Exploring the landscape of tools and resources for the analysis of long non-coding RNAs".
Comput Struct Biotechnol J. 2023;21:4706-4716. doi: 10.1016/j.csbj.2023.09.041. eCollection 2023.
Buonaiuto G, Taliani V, Nicoletti C, Desideri F and Ballarino M 2023 Preparation of cardiac extracts from embryonal hearts to capture RNA-protein interaction by CLIP . Bio-protocol 13(20): e4857. DOI: 10.21769/BioProtoc.4857
Taliani V, Buonaiuto G, Desideri F, Setti A, Santini T, Galfrè S, Schirone L, Mariani D, Frati G, Valenti V, Sciarretta S, Perlas E, Nicoletti C, Musarò A, Ballarino M. 2023 "The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart" Elife. doi: 10.7554/eLife.81360.
Desideri F, D'Ambra E, Laneve P, Ballarino M. 2022 "Advances in endogenous RNA pull-down: A straightforward dextran sulfate-based method enhancing RNA recovery" Front. Mol. Biosci. doi: 10.3389/fmolb.2022.1004746
Carvelli A, Setti A, Desideri F et al, 2022 "A multifunctional locus controls motor neuron differentiation through short and long non coding RNAs", EMBO Journal.
Macino M, Biferali B, Cipriano A, Ballarino M, Mozzetta C. 2021 Targeting the Expression of Long Noncoding RNAs in Murine Satellite Cells from Single Myofibers. Bio Protoc. Nov 5;11:e4209. doi: 10.21769/BioProtoc.4209.
Buonaiuto G, Desideri F, Taliani V, Ballarino M. 2021 "Muscle Regeneration and RNA: New Perspectives for Ancient Molecules". Cells. Sep 23;10(10):2512. doi: 10.3390/cells10102512.
Cipriano A, Macino M, Buonaiuto G, Santini T, Biferali B, Peruzzi G, Colantoni A, Mozzetta C, Ballarino M. 2021 Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells . Elife. Jan 12;10:e54782. doi: 10.7554/eLife.54782.
Desideri F, Cipriano A, Petrezselyova S, Buonaiuto G, Santini T, Kasparek P, Prochazka J, Janson G, Paiardini A, Calicchio A, Colantoni A, Sedlacek R, Bozzoni I, Ballarino M. 2020 Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1 Cell Rep. Dec 22;33:108548. doi: 10.1016/j.celrep.2020.108548.
Santini T, Martone J and Ballarino M. 2021 "Visualization Of Nuclear And Cytoplasmic Long Noncoding RNAs At Single-Cell Level By RNA-FISH", Methods Mol Biol. 2157:251-280. doi: 10.1007/978-1-0716-0664-3_15.
Pagano F, Calicchio A, Picchio V, Ballarino M. 2020 The non-coding side of cardiac differentiation and regeneration , Curr Stem Cell Res Ther. 15(8): 723-738. doi: 10.2174/1574888X15666200123120249.
Rea J, Menci V, Tollis P, Santini T, Armaos A, Garone MG, Iberite F, Cipriano A, Tartaglia GG, Rosa A, Ballarino M, Laneve P, Caffarelli E. 2020 HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade Cell Death Dis. 11(7):527. doi: 10.1038/s41419-020-02738-w.
Martone J, Mariani D, Desideri F and Ballarino M. 2019 "Noncoding RNAs shaping muscle" Front. in Cell and Dev. Biol. 7:394. doi: 10.3389/fcell.2019.00394. eCollection 2019.
Ballarino M, Cipriano A, Tita R, Santini T, Desideri F, Morlando M, Colantoni A, Carrieri C, Nicoletti C, Musarò A, Carroll DO, Bozzoni I. 2018 Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice EMBO J. 37(18). pii: e99697. doi: 10.15252/embj.201899697. Article featured on the COVER of the same issue.
Di Martino D, Colantoni A, Ballarino M Martone J, Mariani D, Danner J, Bruckmann A, Meister G, Morlando M, Bozzoni I. 2018 "The long non coding RNA lnc-31 interacts with Rock1 mRNA and mediates its YB-1-dependent translation" Cell Reports Apr 17;23(3):733-740. doi: 10.1016/j.celrep.2018.03.101
Cipriano A and Ballarino M. 2018 The ever-evolving concept of the gene: the use of RNA/Protein experimental techniques to understand genome functions Front. Mol. Biosci. 6;5:20. doi: 10.3389/fmolb.2018.00020
Ribeiro DM, Zanzoni A, Cipriano A, Delli Ponti R, Spinelli L, Ballarino M, Bozzoni I, Tartaglia GG, Brun C. 2017 Protein complex scaffolding predicted as a prevalent function of long non-coding RNAs Nucleic Acids Res, Nov 20 doi: 10.1093/nar/gkx1169.
Rosa A and Ballarino M, 2016 Divergent lncRNAs take the lead on pluripotent cell differentiation Stem Cell Investigation doi: 10.21037/sci.2016.09.02
Ballarino M, Morlando M, Fatica A and Bozzoni I, 2016 Non-coding RNAs in muscle differentiation and musculoskeletal diseases J Clin Invest. Jun 1;126(6):2021-30.
Rosa A and Ballarino M, 2015 Long non-coding RNA regulation of pluripotency Stem Cells International, July 7; Article ID 296848.
Morlando M, Ballarino M and Fatica A, 2015 Long non-coding RNAs: new players in hematopoiesis and leukemia Front. Med. Apr 14;2:23.
Ballarino M, Cazzella V, D Andrea D, Grassi L, Bisceglie L, Cipriano A, Santini T, Pinnarò C, Morlando M, Tramontano A and Bozzoni I, 2015 Novel lncRNAs in myogenesis: a miR-31 overlapping transcript controls myoblast differentiation Mol Cell Biol Feb;35(4):728-36.
Morlando M, Ballarino M, Fatica A and Bozzoni I, 2014 The role of Long Noncoding RNAs in the Epigenetic Control of Gene Expression ChemMedChem 9(3):505-10.
Di Carlo V, Grossi E, Laneve P, Morlando M, Dini Modigliani S, Ballarino M, Bozzoni I and Caffarelli E, 2013 TDP-43 regulates the microprocessor complex activity during in vitro neuronal differentiation Mol Neurobiol. 48(3):952-63.
Helmrich A*, Ballarino M*, Nudler E and Tora L, 2013 Transcription-replication encounters, consequences and genomic instability Nat Struct Mol Biol 20(4):412-8. *equal contribution.
Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D and Tora L, 2013 TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs Oncogene 32(39):4646-55.
Helmrich A, Ballarino M and Tora L, 2012 Common fragile site instability is linked to transcription Cellular Oncology 35:S23-S23 ISSN: 2211-3428.
Helmrich A, Ballarino M and Tora L, 2011 Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes Mol. Cell 23;44(6):966-77.
Ballarino M, Pagano F, Girardi E, Morlando M, Cacchiarelli D, Marchioni M, Proudfoot NJ, and Bozzoni I, 2009 Coupled RNA processing and transcription of intergenic primary miRNAs Mol Cell Biol 29:5632-8.
Starnes* LM, Sorrentino* A, Pelosi E, Ballarino M, Morsilli O, Biffoni M, Santoro S, Felli N, Castelli G, De Marchis ML, Mastroberardino G, Gabbianelli M, Fatica A, Bozzoni I, Nervi C and Peschle C, 2009 NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls & -globin and G-CSF receptor expression Blood 114:1753-1763 *equal contribution
De Marchis ML, Ballarino M, Salvatori B, Puzzolo MC, Bozzoni I and Fatica A, 2009 A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells Leukemia 23:856-862.
Morlando M, Ballarino M, Gromak N, Pagano F, Bozzoni I and Proudfoot NJ 2008 Primary micro-RNA transcripts are processed co-transcriptionally Nat Struct Mol Biol 15: 902-909.
Fatica A, Rosa A, Ballarino M, Marchis ML, Rasmussen KD and Bozzoni I, 2008 Role of microRNAs in myeloid differentiation Biochem Soc Trans. 36:1201-1205.
Rosa A*, Ballarino M*, Sorrentino A, Sthandier O, De Angelis FG, Marchioni M, Guarini A, Fatica A and Bozzoni I, 2007 The interplay between the master transcription factor PU.1 and two miRNAs regulates human monocyte differentiation PNAS 104:19849-19854 *equal contribution.
Fatica A, Rosa A, Fazi F, Ballarino M, Morlando M, De Angelis FG, Caffarelli E, Nervi C and Bozzoni I, 2006 microRNA and hematopoietic differentiation Cold Spring Harb Symp Quant Biol. vol. LXXI CSHL PRESS 71:205-10
Ballarino M, Morlando M, Pagano F, Fatica A and Bozzoni I, 2005 The cotranscriptional assembly of snoRNPs controls the biosynthesis of H/ACA snoRNAs in S. cerevisiae Mol Cell Biol 25:5396-5403.
Morlando M, Ballarino M, Greco P, Caffarelli E, Dichtl B and Bozzoni I, 2004 Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast EMBO J. 23:2392-2401.
Ballarino M, Marchioni M, Fruscalzo A and Carnevali F, 2004 Identification of positive and negative regulatory regions controlling expression of the X.laevis beta-Trcp gene Gene 336:275-285.
Ballarino M, Marchioni M and Carnevali F, 2002 The Xenopus laevis Trcp Gene: genomic organization, alternative splicing, 5 and 3 region characterization and comparison of its structure with that of human beta-Trcp genes BBA 1577:81-92.
Pubblicazioni in Atti di Congressi Internationali e Corsi
F. Desideri, G. Buonaiuto, V. Taliani, I. Bozzoni, M. Ballarino (2022) "Noncoding RNA shaping gene expression: implications in neuromuscular physiopathology" Regulatory & Non-coding RNAs, CSHL, NY
F. Desideri, A. Setti, A. Carvelli, S. Galfrè, M. Ballarino, P. Laneve, I. Bozzoni (2022) "Noncoding RNA shaping gene expression: implications in motor neurons specification", Regulatory & Non-coding RNAs, CSHL, NY
M. Ballarino (2021) FISHing for Charme, a long noncoding solution to cell differentiation issues EMBO Practical Course: FISHing for RNAs: Classical to Single Molecule Approaches, EMBL Heidelberg, (Germany) virtual, *Invited speaker
I. Bozzoni, J. Martone, M. Morlando, P. Laneve, M. Ballarino, A. Carvelli, F. Pellegrini, V. Padovano, T. Santini, F. Desideri, S. Biscarini. (2021) ncRNAs in motor neuron differentiation and physiopatology Noncoding RNA World: From Mechanism to Therapy, ncRNA 2021, MDPI, virtual
G. Buonaiuto, V. Taliani, F. Desideri, I. Bozzoni, C. Nicoletti, A. Musarò, M. Ballarino (2021) From mouse to human: the nuclear lncRNA Charme as a putative candidate for clinical application? Noncoding RNA World: From Mechanism to Therapy, ncRNA 2021, MDPI, virtual
F. Desideri, G. Buonaiuto, V. Taliani, T. Santini, P. Kasparek, S. Petrezselyova, R. Sedlacek, I. Bozzoni, M. Ballarino (2020) "A comprehensive glimpse on Charme long noncoding RNA 2nd CCP Phenogenomics, Conference 2020 Vestec, (Prague) *Invited speaker
F. Desideri, G. Buonaiuto, V. Taliani, A. Cipriano, A. Calicchio, I. Bozzoni, P. Kasparek, S. Petrezselyova, R. Sedlacek, M. Ballarino (2019) Long noncoding RNAs fine tune myogenesis: a comprehensive glimpse on Charme. EMBO | EMBL Symposium: The Non-Coding Genome, Heidelberg, Germany
F. Desideri, G. Buonaiuto, V. Taliani, A. Cipriano, A. Calicchio, I. Bozzoni, P. Kasparek, S. Petrezselyova, R. Sedlacek, M. Ballarino (2019) Sequence determinants regulating Charme long noncoding RNA epigenetic activities. CCP Phenogenomics Conference 2019, Vestec, Prague
F. Desideri, A. Cipriano, A. Calicchio, G. Buonaiuto, T. Santini, R. Tita, A. Musarò, D. O Carroll, I. Bozzoni and M. Ballarino (2018) Charme Long Noncoding RNA Shapes the 3D Nuclear Structure by its Close Cooperation with Chromatin Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics, Keystone Simposia, Canada
M. Ballarino, F. Desideri, A. Cipriano, R. Tita, T. Santini, C. Nicoletti, A. Calicchio, A. Musaro , I. Bozzoni (2017) Charme lncRNA controls the chromosomal architecture of pro-myogenic genomic loci and regulates heart remodelling EMBO Conference: Nuclear structure and Dynamics, L IIsle sur la Sorgue, France
Cipriano, F. Desideri, R. Tita, T. Santini, C. Nicoletti, A. Calicchio, G. Buonaiuto, A. Musarò, D. O Carroll, I. Bozzoni and M. Ballarino. (2018) The lncRNA Charme regulates skeletal muscle differentiation and heart development . Muscle Meeting Berlin, Germany.
Cipriano, D. Desideri, R. Tita, Santini, C. Nicoletti, A. Calicchio, A. Musaro , D. O Carroll, I. Bozzoni, M. Ballarino (2017) The charming regulation of muscle development and heart remodeling by Charme lncRNA EMBO Symposium: The Non-coding Genome, Heidelberg, Germany
I. Bozzoni, M. Ballarino, M. Morlando, J. Martone, I. Legnini, T. Santini, A. Cipriano, D. Mariani, F. Desideri, D. Dimartino, R. Tita (2017) The control of muscle differentiation: from coding to noncoding RNA and back EMBO Symposium: The Non-coding Genome, Heidelberg, Germany
R. Tita, M. Ballarino, A. Cipriano, F. Desideri and I. Bozzoni (2016) In vivo functional analysis of muscle specific lncRNAs by CRISPR/Cas9 technology Genome Editing & Gene Modulation, Oxford (UK)
A. Cipriano, M. Ballarino, R. Tita, F. Desideri and I. Bozzoni (2016) Characterization of a lncRNA involved in skeletal and cardiac muscle differentiation EMBO Conference: RNA structure meets function, Stockholm Archipelago, Sweden
D. Dimartino, M. Morlando, M. Ballarino, S. Shamloo, J. Martone and I. Bozzoni (2015) Defining the role of newly identified long non-coding RNAs in myogenesis EMBO Conference: The Non-Coding genome, Heidelberg, Germany
S. Shamloo, J. Martone, M. Ballarino, D. Mariani and I. Bozzoni (2015) Identification, validation, and classification of novel lncRNAs with a putative role in muscle differentiation International Conference on the Long and the Short of Non-Coding RNAs, Chania, Crete, Greece
M. Ballarino, A. Cipriano, R. Tita, L. Bisceglie, T. Santini and I. Bozzoni. (2015) The long non-coding RNA lnc-405 is a nuclear transcript which promotes myoblasts differentiation EMBO Conference: Chromatin and Epigenetics, Heidelberg (Germany)
R. Tita, A. Cipriano, L. Bisceglie, M. Ballarino and I. Bozzoni (2015) In vivo study of the long-non coding RNA lnc-405 in myogenesis. (2015) PHENOMIN European School for Advanced Mouse Phenogenomics, Château du Liebfrauenberg, Alsace, (France)
L. Bisceglie, M. Ballarino, A. Cipriano, R. Tita and I. Bozzoni (2015) RNAseq profiling identifies novel lncRNAs modulated during murine myogenesis , Non-Coding Genome, Institut Curie Training unit International Course, Paris (France)
M. Ballarino, M. Morlando, A. Cipriano, L. Bisceglie and I. Bozzoni (2014) Novel RNAs during in vitro myogenesis: a lncRNA overlapped to miR-31 controls the timing of murine myoblast differentiation ESF EMBO Symposium Long Regulatory RNAs, Pultusk (Poland)
M. Ballarino, V. Cazzella, C. Pinnaro`, L. Bisceglie, D. D Andrea, L. Grassi, T. Santini, A. Tramontano and I. Bozzoni (2013) Long non coding RNAs and muscle differentiation The Regulatory Roles of ncRNA" Workshop, Baeza (Spain)
M. Ballarino, B. Gu, C. Keime, O. Bensaude and L. Tora (2011) The novel TAF15-U1 snRNP has a splicing independent function necessary for the maturation of intron-encoded ncRNAs Nuclear Structure and Dinamics EMBO Workshop, L isle sur la Sorgue (France)
Morlando M, Ballarino M, Pagano F, Girardi E, Cacchiarelli D, Marchioni M, Proudfoot N, Bozzoni I. Coupling between transcription and processing promotes efficient expression of independently transcribed microRNA genes . SIROCCO Annual Meeting (2009), Hinxton, Cambridge (UK)
M. Morlando, M. Ballarino, F. Pagano, E. Girardi, D. Cacchiarelli, M. Marchioni, N.J. Proudfoot, I. Bozzoni (2009) Coupling between transcription and processing promotes efficient expression of independently transcribed microRNA genes Messenger RNA 3 ends and gene expression EMBO Workshop, University of Oxford (UK)
M. Ballarino (2009) Coupled RNA processing and transcription of intergenic primary miRNAs ESF RNA quality Workshop, Gyf-sur-Yvette (France)
M. Morlando, M. Ballarino, F. Pagano, E. Girardi, D. Cacchiarelli, N.J. Proudfoot and I. Bozzoni (2009) RNA processing and transcription are tightly coupled for the intergenic miRNAs biogenesis The Biology of RNA Silencing Keystone Symposia, Canada
E. Girardi, M. Ballarino, J. Martone, D. Cacchiarelli, M. Cesana, I. Bozzoni (2008) The molecular and cellular mechanisms regulating skeletal muscle development and re generation EMBO Conference Series (1°) Sant Feliu de Guixols (Spain)
M. Morlando, F. Pagano, E. Girardi, D. Cacchiarelli, M. Ballarino, and I. Bozzoni (2008) Drosha processing and miRNA transcription RNAQuality meeting, Granada (Spain)
M. Morlando, M. Ballarino, N. Gromak, F. Pagano, D. Cacchiarelli, E. Girardi, N.J. Proudfoot and I.Bozzoni (2008) Microprocessor complex processes primary micro-RNA transcript during transcription Thirteenth Annual Meeting of the RNA Society, Berlino (Germany)
F. Pagano, M. Ballarino, M. Morlando, E. Girardi, M. Marchioni and I. Bozzoni (2008) New connections between microRNAs transcription and processing Sirocco/Right Young Scientists Symposium, Cambridge (UK)
M. Ballarino, A. Rosa, O. Sthandier, F. De Angelis, M. Marchioni, A. Fatica, I. Bozzoni (2007) Role of microRNAs in human myelopoiesis RNA 2007, Madison Wisconsin
E. Caffarelli, P. Laneve, M. Morlando, M. Fiori, M. Ballarino, S. Ghinaglia, A. Rosa, A. Fatica, I. Bozzoni (2005) Characterisation of the sequences required for the regulation of the miRNA expression RNA 2005, Banff, Alberta, Canada
M. Morlando, M. Ballarino, S. Ghinaglia, F. Pagano, T. Moschetti, A. Fatica and I. Bozzoni (2005) Coupling between co-transcriptional snoRNPs assembly and 3 -end formation in yeast . EMBO Conference Messenger RNA 3 ends: interconnections with transcription and mRNA turnover , Sir William Dunn School of Pathology & Brasenose College, University of Oxford (UK)
M. Morlando, M. Ballarino, F. Pagano, T. Moschetti, S. Ghinaglia, E. Caffarelli, A. Fatica and I. Bozzoni (2004) Factory of small non coding RNA in Saccharomyces cerevisiae Workshop Coupling between transcription and RNA processing Baeza (Spain)
M. Ballarino, M. Morlando, T. Moschetti, E. Caffarelli, A. Fatica, and I. Bozzoni (2004) Influence of polII CTD phosphorylation on snoRNA assembly and termination RNA 2004, Madison Wisconsin
Pubblicazioni in Atti di Congressi Nazionali e Corsi
G. Buonaiuto,V. Taliani, F. Desideri, M. Ballarino (2022). "From mouse to human: how RNA epigenetic influences cardiac and neuromuscular physiology and disease" ABCD National Ph.D. Meeting, Salerno (NA)
F. Desideri, A. Cipriano, G. Buonaiuto, T. Santini, V. Taliani, S. Petrezselyova, A. Colantoni, C. Nicoletti, A. Musarò, I. Bozzoni, M. Ballarino (2020). On the impact of nuclear long noncoding RNAs in myogenesis: Charme interacts with the chromatin to fine-tune muscle specification Pathogenesis and Therapies of Neuromuscular Diseases 17th IIM-Myology Meeting (virtual)
M. Macino, A. Cipriano, G. Buonaiuto, T. Santini, B. Biferali, G. Peruzzi, A. Colantoni, C. Mozzetta, M. Ballarino (2020). Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA lnc-Rewind in muscle stem cells . Pathogenesis and Therapies of Neuromuscular Diseases 17th IIM-Myology Meeting (virtual)
G. Buonaiuto, F. Desideri, V. Taliani, T. Santini, I. Bozzoni, M. Ballarino (2019) Deciphering the long noncoding RNAs language in myogenesis: a comprehensive glimpse on Charme MEETING del Dipartimento di Biologia e Biotecnologie C. Darwin , Sapienza Università di Roma (RM)
G. Buonaiuto, F. Desideri, V. Taliani, T. Santini, A. Colantoni, E. Perlas, C. Nicoletti, A. Musarò, I. Bozzoni, M. Ballarino (2019) Deciphering the long noncoding RNAs language in myogenesis: a comprehensive glimpse on Charme ShareScience 2019 Sapienza Università di Roma (RM)
M. Ballarino (2018) Non-coding regulation of myogenic chromatin EPIGEN Final Meeting, San Servolo, Venice *Invited speaker
A. Cipriano, F. Desideri, R. Tita, T. Santini, C. Nicoletti, A. Calicchio, C. Carrieri, A. Musaro, D. O Carroll, I. Bozzoni, M. Ballarino (2018) The Charming regulation of muscle development and heart remodelling by Charme lncRNA SIBBM 2018, Roma (RM) *Invited speaker
M. Ballarino, A. Cipriano, F. Desideri, T. Santini, C. Nicoletti, A. Calicchio, G. Buonaiuto, M. Morlando, A. Musarò, I. Bozzoni. (2018) Non-coding regulation of myogenic chromatin SIBBM 2018, Roma (RM)
F. Desideri, A. Cipriano, A. Calicchio, R. Tita, A. Musarò, I. Bozzoni, M. Ballarino (2017) Analysis of 3D chromatin conformation structures mediated by the long noncoding RNA Charme ABCD Meeting, Bologna (BO)
M. Ballarino, A. Cipriano, F. Desideri, R. Tita, T. Santini, C. Nicoletti, A. Calicchio, A. Musarò, I. Bozzoni. (2017) Charme lncRNA controls the chromosomal architecture of pro-myogenic genomic loci and regulates heart remodelling Ponzano Meeting, Ponzano Romano (Italy)
D. Dimartino, M. Morlando, A. Colantoni, M. Ballarino, S. Shamloo, J. Martone and I. Bozzoni. (2016) Newly identified long non-coding RNAs promote proliferation and differentiation of murine myoblasts XIV Convegno FISV, Roma (RM)
R. Tita, M. Ballarino, A. Cipriano, F. Desideri, I. Bozzoni. (2016) A new murine long non-coding RNA conserved in human and involved in muscle differentiation SIGU, Turin (Italy)
M. Ballarino, R. Tita, A. Cipriano, F. Desideri and I. Bozzoni (2016) Lnc-405 interacts with Pur / proteins to regulate myogenic differentiation SIBBM 2016, Napoli
A. Cipriano, R. Tita, L. Bisceglie, M. Ballarino and I. Bozzoni (2015) Characterization of a nuclear lncRNA involved in skeletal and cardiac muscle differentiation IIM Myology Meeting, Reggio Emilia
J. Martone, M. Ballarino, F. Briganti, I Legnini, A. Cipriano, L. Bisceglie, S. Shamloo, Bozzoni I. (2015) RNA-based gene therapy of Duchenne Muscular Dystrophy Fondazione Telethon, XVIII Scientific Convention, Riva del Garda (TN)
M. Ballarino, V. Cazzella, M. Morlando, L. Bisceglie, A. Cipriano, C. Pinnarò, A. Tramontano, I. Bozzoni (2014) Identification of novel lncRNAs modulated during myogenic differentiation in mouse Molecular biology of muscle development and regeneration EMBO Workshop, Lecce
M. Morlando, I. Legnini, A. Mangiavacchi, M. Ballarino, V. Cazzella, A. Fatica, I. Bozzoni (2014) The interplay between the HUR protein and the long non-coding RNA linc-MD1 drives the progression from early to late muscle differentiation stages Molecular biology of muscle development and regeneration EMBO Workshop, Lecce
E. Girardi, M. Ballarino, M. Marchioni, I. Bozzoni (2008) Analysis of the transcription machinery of the microRNA genes 4th SIBBM Seminar, Frontiers in Molecular Biology, Milano
F. Pagano, E. Girardi, D. Cacchiarelli, M. Ballarino and I. Bozzoni (2007) The RNAseIII Drosha controls miRNA biogenesis during transcription 9° Convegno FISV, Riva del Garda (TN)
A. Rosa, M. Ballarino, P. Laneve, U. Gioia, M. L. De Marchis, F. Pagano, E. Girardi, D. Cacchiarelli, F. Moretti, O. Sthandier, F. G. De Angelis, E. Caffarelli A., Fatica, I. Bozzoni (2007) miRNAs as novel players in molecular circuitries controlling cell differentiation The world of small non-coding RNAs: from basic to applied science, Accademia Nazionale dei Lincei, Roma
M. Ballarino, M. Morlando, F. Pagano, A. Fatica, I. Bozzoni (2006) The Factory of small non coding RNA , First ROC International Workshop, Roma
E. Girardi, F. Pagano, M. Ballarino, M. Morlando, M. Marchioni, A. Fatica, I. Bozzoni (2006) Non-canonical RNA factories for non-coding RNA genes , First ROC International Workshop, Roma
E. Girardi, F. Pagano, M. Ballarino, M. Morlando, M. Marchioni, A. Fatica, I. Bozzoni (2006) non-canonical RNA factories for non-coding RNA genes , 8° Convegno FISV, Riva del Garda (TN)
A. Rosa, M. Ballarino, F.G. De Angelis, T. Incitti, O., Sthandier A. Fatica, I. Bozzoni (2006) Role of micrornas in myeloid differentiation , II IFOM-IEO Campus, Meeting on Cancer, Milano
M. Ballarino, A. Rosa, F. Pagano, E. Girardi, M. Marchioni, I. Bozzoni (2006) Identification of factors regulating hematopoietic microRNAs transcription , EMBO/SEMM Workshop on Homeodomain proteins, hematopoietic development and Leukemias, Riva del Garda (TN)
F. Pagano, M. Morlando, M. Ballarino, S. Ghinaglia, A. R. Cerroni, M. Arceci, A. Fatica, I. Bozzoni (2005) Cotranscriptional assembly of ribonucleoparticles controls the biosynthesis of RNA polymerase II non-coding transcripts , 7° Convegno FISV, Riva del Garda (TN)
M. Fiori, E. Caffarelli, P. Laneve, M. Morlando, M. Ballarino, S. Ghinaglia, A. Rosa, A. Fatica, I. Bozzoni (2005) Characterization of the sequences required for the regulation of the miRNA expression , Milano
M. Ballarino, M. Morlando, F. Pagano, T. Moschetti, S. Ghinaglia, E. Caffarelli, A. Fatica and I. Bozzoni (2004) Factory of small non coding RNAs in Saccharomyces cerevisiae 6° Convegno FISV, Riva del Garda (TN)
M. Morlando, M. Ballarino, Greco P., Caffarelli E., Dicht D. and I. Bozzoni. (2004) RNA-protein interactions on nascent snoRNA transcripts regulate 3 -end formation RNA-2 day, Roma
M. Morlando, P. Greco, T. Moschetti, M. Ballarino, R. Simone e I. Bozzoni (2003) Accoppiamento tra eventi trascrizionali e post-trascrizionali nella biosintesi degli snoRNA 5° Convegno FISV, Rimini
M. Ballarino, A. Fruscalzo, M. Marchioni, F. Carnevali (2003) The X.laevis beta-Trcp gene promoter is a target of catenin/Tcf-3 pathway 5° Convegno FISV, Rimini
M. Ballarino, M. Marchioni, F. Carnevali (2002) Analisi di beta-Trcp, un regolatore negativo del pathway Wnt e della specificazione del pattern dorso-ventrale nell embrione di Xenopus laevis Convegno SIBBM Struttura e Funzione del Genoma , Cortona (AR)
M. Ballarino, M. Marchioni, F. Carnevali (2002) Il gene beta-Trcp di Xenopus laevis: struttura genomica, isoforme di splicing e regolazione trascrizionale 4°Convegno FISV, Riva del Garda (TN)
M. Ballarino, A. Fruscalzo, M. Marchioni, F. Carnevali (2001) Analisi strutturale e funzionale del gene beta-Trcp in Xenopus laevis , 3° Convegno FISV, Riva del Garda (TN)
M. Ballarino, G. Lagna, Ali Hemmati-Brivanlou, M. Marchioni, F. Carnevali (2000) Regolazione negativa della formazione dell asse e della segnalazione di Wnt in embrioni di Xenopus da parte della proteina beta-Trcp , 2° Convegno FISV, Riva del Garda
Partecipazione a Progetti di Ricerca Nazionali e Internazionali (EU)
2020 Sapienza Ricerca Bandi di Ateneo. Titolo Drosophila melanogaster as a model for unveiling conserved factors involved in cancer stem cell radioresistance n. protocollo RM120172B7D32C04
2019 Progetti di ricerca Medie Attrezzature Scientifiche, Sapienza Ateneo. Titolo Sequenziamento di lunghe molecole di DNA/RNA per lo studio di organismi modello e non modello , MA11916B7BEBDEB8
2018 Sapienza Ricerca Bandi di Ateneo (Medi). Ministero dell'istruzione, dell'università e della ricerca. Titolo New therapeutic approach for Duchenne Muscular Dystrophy , RM118164363B1D21
2017 PRIN2017 Prot. 2017P352Z4 Non coding RNAs, new players in gene expression regulation: studying their role in neuronal differentiation and neurodegeneration
2016 Telethon2016 «RNA-based studies of DMD: post-transcriptional control and role of noncoding RNAs in normal and dystrophic muscle development» No. GGP16213
2014 Acquisizione di medie e grandi attrezzature scientifiche, Sapienza Ateneo Studio del profilo di espressione di mRNA e miRNA tramite PCR quantitativa"
2013 ERC Adv Grant «Role of long non coding RNA in muscle differentiation and disease» GA 340172 MUNCODD
2013 Progetti AWARDS, prot. C26H13WW7B Sapienza Università di Roma
2012 EPIGENOMICS FLAGSHIP PROJECT (Progetto Bandiera Epigenomica)
2012 AFM-Telethon «Role of long non coding RNAs in muscle differentiation and in Duchenne Muscular Dystrophy (DMD)» No. 17835
2009 AIRC miRNA function and misfunction in tumour cells No. 8723 IG2009
2009 Progetti di Ricerca di Università, prot. C26A092PFW Sapienza Università di Roma
2007 PRIN «Ruolo dei microRNA nel differenziamento cellulare e nella tumorigenesi» prot. 20077YZTL8
2005 PRIN «La fabbrica dell'RNA: accoppiamento tra processi trascrizionali e post-trascrizionali nella biosintesi di piccoli RNA non codificanti» prot. 2005050339_002
2005 UE FP6-LIFESCIHEALTH- SIROCCO grant No. 037900
2003 PRIN «La fabbrica dell RNA dei geni TOP: ruolo delle regioni del promotore sul processamento dei piccoli RNA nucleolari intronici» prot. 2003054827_002
Finanziamenti (PI)
2022 Progetto PRIN 2022 PNRR (P2022FFEWN, RNA2Fun)
2022 Progetto PRIN 2022 (2022BYB33L,NOMeN)
2022 Progetto PNRR Spoke 3, CUP B83C22002870006, linea tematica 2. PI and task leader 3.2.5
2021 Sapienza Ateneo n. protocollo RM12117A5DE7A45B
2020 PROGETTI DI GRUPPI DI RICERCA 2020 POR FESR Lazio Titolo: Soluzione Integrata di Microscopia Brillouin Avanzata A03752020-36389
2019 Sapienza Ateneo n. protocollo RM11916B7A39DCE5
2017 INFRAFRONTIER-Disease model development and systemic phenotyping "Generation and Phenotyping of the Charme lncRNA deficient mice
2017 FFABR ANVUR (2017). Ministero dell'istruzione, dell'università e della ricerca
2017 Sapienza Ateneo n. protocollo RM11715C7C8176C1
Premi
2019 Riconoscimento di "Eccellente Insegnamento Universitario", Facoltà di Scienze Matematiche Fisiche Naturali, Sapienza
2015 Miglior Poster Telethon (2015) XVIII Scientific convention, Riva del Garda, Italia
2010 Long-Term fellowship FRM-Fondation pour la Recherche Medicale, Francia
2009 Miglior Poster SIROCCO (2009) Annual meeting, Hinxton, (UK)
2004-05 Premio di Studio Fondazione TELETHON prog. N. GSP030543C
Esperienze di Insegnamento e Tutoraggio studenti:
Didattica FRONTALE:
dal 2019: MOLECULAR BIOLOGY (CFU:6, 60 ore), Laurea Magistrale in Fisica (LM17), Facoltà di SMFN, Sapienza, Roma
dal 2018: MOLECULAR BIOLOGY AND GENOMICS (CFU:6, 48 ore), Laurea Triennale in Bioinformatics (L-2), Facoltà di Farmacia e Medicina, Sapienza, Roma
dal 2017: GENOMICA (modulo 2) (CFU:3, 24 ore), Laurea Triennale in Scienze Biologiche (L-13), Facoltà di SMFN, Sapienza, Roma
2013-18: INGEGNERIA GENETICA E TERAPIA GENICA (CFU:3, 24 ORE), Laurea Magistrale in Biotecnologie GIA, Facoltà di SMFN, Sapienza, Roma
2014-17: Lecturer per il corso di EPIGENETIC CONTROL OF GENE EXPRESSION (CEEG), (Docente titolare: prof. G. Camilloni), Laurea Magistrale in Genetica e Biologia Molecolare nella Ricerca di Base e Biomedica (GBMRBB), Facoltà di SMFN, Sapienza, Roma
Didattica INTEGRATIVA:
- Lecturer per il corso di GENE EXPRESSION REGULATION OF EUKARYOTES (Docente titolare: prof. I. Bozzoni), Laurea Magistrale in Genetica e Biologia Molecolare, Facoltà di SMFN, Università Sapienza , Roma
- Lecturer per la "Scuola Superiore di Studi Avanzati" Sapienza su Metodi per l analisi di acidi nucleici e proteine . I-II anno, area Scienze della Vita
- Lecturer per le scuole di Dottorato in:
Genetics and Molecular Biology, Università Sapienza, Roma
"LncRNAs in muscle differentiation"
"Immunoprecipitation and beyond: new and improved methodologies to detect RNA/protein interactions with chromatin"
"Methodological issues and challenges for probing the function of long noncoding RNAs"
Morphogenesis and Tissue Engineering, Sapienza, Roma
"A noncoding solution to cell differentiation issues: the Charme example"
Membro delle Commissioni di Esame per i Corsi di:
- REGOLAZIONE DELL'ESPRESSIONE GENICA NEGLI EUCARIOTI (Docente titolare: prof. A. Fatica), Laurea Magistrale in Genetica e Biologia Molecolare, Facoltà di SMFN, Sapienza
- GENE EXPRESSION REGULATION OF EUKARYOTES (Docente titolare: prof. I. Bozzoni), Laurea Magistrale in Genetica e Biologia Molecolare, Facoltà di SMFN, Sapienza
Tutoraggio di studenti durante i loro progetti di tesi in Scienze Biologiche, Specialistica in Genetica e Biologia Molecolare o tesi di Dottorato c/o BBCD, Sapienza
Partecipazione in qualità di Insegnante al First ROC practical course on ChIP related techniques, 2006 , Regina Elena Cancer Institute CRS-IRE Roma, Italia
Coordinatrice dei "seminari del mercoledì" c/o Dip. Biologia e Biotecnologie Charles Darwin , Sapienza Università di Roma
Organizzatrice del 1st EMBL Sapienza Chromatin and Epigenetics PhD meeting, 26/27 Settembre 2016, Sapienza Università di Roma
Responsabilità Istituzionali ed Editoriali
2021-oggi Membro del Consiglio Tecnico Scientifico SPBA-Centro Servizi e Ricerca, sperimentazione preclinica benessere animale
2021-oggi Membro della Giunta di Dipartimento (BBCD, Sapienza)
2019 oggi Socio Ordinario Accademia Medica
2018 oggi Membro SIBBM
2017 oggi Membro del collegio dei docenti del Dottorato in Genetics and Molecular Biology, Sapienza Università di Roma
2017 oggi Editore Associato per la rivista Frontiers Molecular Bioscience Journal"