MICHELE GRASSO

Dottore di ricerca

ciclo: XXXIV



Titolo della tesi: Impact of early decannulation on dysphagia outcomes following supracricoid laryngectomy

OBJECTIVES: Early decannulation, performed within the first ten days after supracricoid partial laryngectomy, can result in a more rapid recovery of swallowing function with a semisolid bolus in the short term, about 30 days. METHODS: We selected 20 patients with squamous cell carcinoma of larynx, who underwent supracricoid laryngectomies: 10 cricohyoidopexy (CHP) and 10 cricohyoidoepiglottopexy (CHEP). Staging was pT2 (10 pts), and pT3 (10 pts). Fiberoptic Endoscopic Evaluation of Swallowing (FEES) was used to assess postoperative swallowing function after a mean of 12 and 22 days from surgery. A modified PAS Score (Penetration-Aspiration Scale) was assigned for subtotal laryngectomies. RESULTS: Decannulation occurred after 6.7 ± 2.1 days. Univariate analysis showed that the type of surgery (CHP or CHEP), pT, resection of one arytenoid, and decannulation time are significantly associated with the 12-day PAS Score. The 22-day PAS score is significantly associated with only 3 variables: type of surgery, pT, and resection of one arytenoid. CONCLUSION: From the data presented, the factors that most delay an effective recovery of swallowing are T3 and the resection of one arytenoid. Early decannulation has been shown statistically to improve PAS score in the short term, but not in the long term. In the literature, the average decannulation time ranges from 8 to 105 days, with a decannulation rate ranging from 85.7% to 100% of patients.

Produzione scientifica

  • 11573/780774 - 2014 - Recurrent respiratory papillomatosis by HPV: review of the literature and update on the use of cidofovir. (01a Articolo in rivista)
    FUSCONI, MASSIMO; GRASSO, MICHELE; GRECO, ANTONIO; GALLO, ANDREA; CAMPO, FLAMINIA; TURCHETTA, ROSARIA; PAGLIUCA, GIULIO; DE VINCENTIIS, MARCO
  • 11573/1678174 - 2023 - Partial horizontal supracricoid laryngectomy: which factors impact on post‐decannulation swallowing outcomes? A prospective single‐center experience (01a Articolo in rivista)
    GRASSO, MICHELE; FUSCONI, MASSIMO; BELLIZZI, MARIO GIUSEPPE; FLACCADORO, FLAVIA; AGOLLI, GRISELDA; RUOPPOLO, GIOVANNI; DE VINCENTIIS, MARCO; RALLI, MASSIMO; DI STADIO, ARIANNA; COLIZZA, ANDREA; GRECO, ANTONIO
  • 11573/517196 - 2013 - Rosai-Dorfman disease in the larynx (01b Commento, Erratum, Replica e simili)
    FUSCONI, MASSIMO; BENINCASA, ANNA TERESA; GRASSO, MICHELE; DE VINCENTIIS, MARCO
  • 11573/1281487 - 2017 - Response to letter to Editor: "The clinical course of recurrent respiratory papillomatosis after the use of cidofovir is influenced by multiple factors" (01f Lettera, Nota)
    GRASSO, MICHELE
  • 11573/1281481 - 2014 - Use of cidofovir in HPV patients with recurrent respiratory papillomatosis (01a Articolo in rivista)
    GRASSO, MICHELE
  • 11573/1345307 - 2018 - The effectiveness of long-term course of Sterimar Mn nasal spray for treatment of the recurrence rates of acute allergic rhinitis in patients with chronic allergic rhinitis (01a Articolo in rivista)
    GRASSO, MICHELE; DE VINCENTIIS, MARCO; AGOLLI, GRISELDA
  • 11573/1381235 - 2020 - Laryngeal tuberculosis in renal transplant recipients: a case report and review of the literature (01i Case report)
    CIALENTE, FABRIZIO; GRASSO, MICHELE; RALLI, MASSIMO; DE VINCENTIIS, MARCO; MINNI, ANTONIO; AGOLLI, GRISELDA; DELLO SPEDALE VENTI, MICHELE; RIMINUCCI, MARA; CORSI, ALESSANDRO; GRECO, ANTONIO
  • 11573/1010649 - 2017 - Day-case management of chronic suppurative otitis media with cholesteatoma with canal wall down technique surgery: long-term follow-up (01a Articolo in rivista)
    RALLI, GIOVANNI; GRASSO, MICHELE; RALLI, MASSIMO
  • 11573/1412722 - 2018 - Interleukin-8 and laryngeal squamous cell carcinoma (01a Articolo in rivista)
    GRASSO, MICHELE; RALLI, MASSIMO; AGOLLI, GRISELDA; FIORE, MARCO; CECCANTI, MAURO; DE VINCENTIIS, MARCO; GRECO, ANTONIO
  • 11573/1398816 - 2020 - Lingual cyst with respiratory epithelium: the importance of differential diagnosis (01f Lettera, Nota)
    CIALENTE, FABRIZIO; DE SOCCIO, GIULIA; SAVASTANO, VINCENZO; GRASSO, MICHELE; DELLO SPEDALE VENTI, MICHELE; RALLI, MASSIMO; RIMINUCCI, MARA; DE VINCENTIIS, MARCO; CORSI, ALESSANDRO; MINNI, ANTONIO
  • 11573/1587182 - 2021 - Squamous cell papilloma-like presentation of multiple neurovascular hamartomas of the oral cavity (01i Case report)
    COLIZZA, ANDREA; RALLI, MASSIMO; GRASSO, MICHELE; RIMINUCCI, MARA; GRECO, ANTONIO; DE VINCENTIIS, MARCO; CORSI, ALESSANDRO
  • 11573/1612173 - 2021 - Rupture of the pleomorphic adenoma of the parotid gland: what to know before, during and after surgery (01a Articolo in rivista)
    GRASSO, MICHELE; FUSCONI, MASSIMO; CIALENTE, FABRIZIO; DE SOCCIO, GIULIA; RALLI, MASSIMO; MINNI, ANTONIO; AGOLLI, GRISELDA; DE VINCENTIIS, MARCO; D'ANDREA, VITO; GRECO, ANTONIO
  • 11573/1655114 - 2021 - Approccio laterocervicale nelle Open Partial Horizontal Laryngectomies (OPHL): outcome oncologici e funzionali. (04d Abstract in atti di convegno)
    COLIZZA, ANDREA; MINNI, ANTONIO; RALLI, MASSIMO; GRECO, ANTONIO; GRASSO, MICHELE; ANGELETTI, DILETTA; DE VINCENTIIS, MARCO
  • 11573/1412835 - 2020 - The role of cytokines in head and neck squamous cell carcinoma: a review (01a Articolo in rivista)
    RALLI, MASSIMO; GRASSO, MICHELE; GILARDI, ANTONIO; CECCANTI, MAURO; MESSINA, MARISA PATRIZIA; FIORE, MARCO; ALTISSIMI, GIANCARLO; DE VINCENTIIS, MARCO; GRECO, ANTONIO

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma