MARTINA BRUNETTI

PhD Student

PhD program:: XL
email: martina.brunetti@uniroma1.it




supervisor: Prof.ssa Zein Mersini Besharat
co-supervisor: Dott.ssa Elena Splendiani

Research: Bioinformatic approaches for the analysis of spatial transcriptomic data in solid tumors

Education and Training
PhD in Network Oncology and Precision Medicine 11/2024 - Present Department of Experimental Medicine Sapienza University of Rome, Rome, Italy
Research Fellowship 04/2024 - 10/2024 Department of Experimental Medicine Sapienza University of Rome, Rome, Italy Validation of molecular biomarkers of disease using artificial intelligence-based algorithmic modelling
Research Scholarship 01/2023 - 10/2023 Department of Computer, Control and Management Engineering “Antonio Ruberti” Sapienza University of Rome, Rome, Italy Identification of putative novel molecular biomarkers and/or therapeutic targets using drug repositioning software for pan-cancer analysis
Master’s Degree in Biomedical Engineering 09/2021 - 10/2023 Sapienza University of Rome, Rome, Italy Curriculum: Computational Medicine Final grade: 110/110 cum laude Thesis: Bioinformatic analysis of biological networks for the identification of repositionable active molecules in different types of human cancers

Work Experience
Tutor - Biomedical Engineering (L-9) 01/12/2025 - 31/07/2026 San Raffaele Telematic University of Rome, Rome, Italy Skills Programming: Python, R, MATLAB, Bash Omics Data Analysis: Bulk and single-cell RNA-seq, spatial transcriptomics Computational Analysis: Statistical data analysis; machine learning applications; network-based approaches for drug repurposing Research Project: Bioinformatic approaches for the analysis of spatial transcriptomic data in solid tumors Development and optimization of bioinformatics pipelines for the analysis of spatial transcriptomics data generated using Open-ST, an innovative platform that preserves the spatial information associated with transcripts captured within tissue sections.

Research products

11573/1764762 - 2026 - Delivery of miR-139–5p from responsive human serum albumin nanoparticles boosts doxorubicin biological effects on triple negative breast cancer cells
Curcio, Manuela; Pediconi, Natalia; Brunetti, Martina; Spinello, Zaira; Raia, Tiziana; Citarella, Anna; Scorzafave, Ludovica; Nicoletta, Fiore Pasquale; Avena, Paola; Casaburi, Ivan; Palamà, Ilaria Elena; Besharat, Zein Mersini; Po, Agnese; Cirillo, Giuseppe; Iemma, Francesca; Ferretti, Elisabetta; Catanzaro, Giuseppina - 01a Articolo in rivista
paper: COLLOIDS AND SURFACES. B, BIOINTERFACES (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0927-7765 - wos: WOS:001623736400001 (0) - scopus: 2-s2.0-105021981193 (1)

11573/1730124 - 2024 - Study of Circulating MicroRNAs as biomarkers for guided Immunotherapy in Head and Neck carcinoma patients: A tool for personalized medicine
Autilio, Tanja Milena; Cirillo, Alessio; Besharat, Zein Mersini; Trocchianesi, Sofia; Citarella, Anna; Brunetti, Martina; Santini, Daniele; Botticelli, Andrea; Ferretti, Elisabetta - 04f Poster
conference: 36th AICC INTERNATIONAL MEETING – HIJACKING THE «GOOD» PATHWAYS (Roma)
book: 36th AICC INTERNATIONAL MEETING – HIJACKING THE «GOOD» PATHWAYS - ()

11573/1737280 - 2024 - A network-based bioinformatic analysis for identifying potential repurposable drugs for obesity avoiding hepatic steatosis side-effect
Brunetti, M.; Fiscon, G.; Di Costanzo, A.; Arca, M.; Paci, P. - 04b Atto di convegno in volume
conference: 2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024 (Lisbon, Portugal)
book: 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) - (9798350386226)

11573/1693907 - 2023 - Breast Cancer Epidemic Model and Optimal Control
Brunetti, Martina; Di Giamberardino, Paolo; Iacoviello, Daniela; Ingrosso, Marialourdes - 04b Atto di convegno in volume
conference: International Conference on Informatics in Control, Automation and Robotics (Rome; Italy)
book: ICINCO 2023 20th International Conference on Informatics in Control, Automation and Robotics - (9789897586705)

11573/1702302 - 2023 - A network-based bioinformatic analysis for identifying potential repurposable active molecules in different types of human cancers
Brunetti, M.; Paci, P.; Fiscon, G. - 04b Atto di convegno in volume
conference: 2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023 (Istanbul; Turkiye)
book: Proceedings of the 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) - ()



Le attività presentate in questa pagina sono finanziate totalmente, o in parte, dai fondi del Piano nazionale di ripresa e resilienza.
L'elenco e le finalità delle attività intraprese dalla Sapienza sono descritte nella pagina dedicata Sapienza per il Pnrr.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma