Education and qualifications
January 2021 National Scientific Qualification 05/B2 – Comparative Anatomy and Cytology (Associate Professor) - Anatomia Comparata e Citologia (II fascia)
February 2019 Qualification to the functions of Maître de conférences (Senior Lecturer) - Cell Biology Section, number 19265331178 – Ministry of National education and youth – Ministry of high education, research and innovation – France
December 2011 Post Master's degree in Dietetics and Nutrition at the Università Cattolica del Sacro Cuore – Rome.
May 2011 Italian professional qualification as Biologist (Esame di stato per l’abilitazione alla professione di biologo) with final note 150/150 – University of L'Aquila - Italy
February 2008 Obtaining of double PhD degree for joint research doctoral thesis in Development and Cellular Biology from University of Rome Sapienza – Italy – and in Science de la Vie from Université de Bourgogne – Dijon (France).
July 2004 Master's degree in Biology (specialisation in Biotechnology) (5 years) – University of Rome Sapienza, Italy – with final note 110/110 cum laude.
Publications (according to Scopus)
1. Mathew AR, Cavallucci V, Fidaleo M. Altered vitamin B12 metabolism in the central nervous system is associated with the modification of ribosomal gene expression: new insights from comparative RNA dataset analysis. Funct Integr Genomics. 2023 Jan 23;23(1):45. doi: 10.1007/s10142-023-00969-6. PMID: 36683116; PMCID: PMC9868042.
2. Engelmann C, Habtesion A, Hassan M, Kerbert AJ, Hammerich L, Novelli S, Fidaleo M, Philips A, Davies N, Ferreira-Gonzalez S, Forbes SJ, Berg T, Andreola F, Jalan R. Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in amouse model of ACLF (2022) Journal of Hepatology, 77 (5), pp. 1325-1338
3. Panzarini E, Leporatti S, Tenuzzo BA, Quarta A, Hanafy NAN, Giannelli G, Moliterni C, Vardanyan D, Sbarigia C, Fidaleo M, Tacconi S, Dini L. Therapeutic Effect of Polymeric Nanomicelles Formulation of LY2157299-Galunisertib on CCl4-Induced Liver Fibrosis in Rats. J. Pers. Med. 2022, 12, 1812. https://doi.org/10.3390/jpm12111812
4. Tacconi S, Augello S, Persano F, Sbarigia C, Carata E, Leporatti S, Fidaleo M, Dini L. Amino- functionalized mesoporous silica nanoparticles (NH2-MSiNPs) impair the embryonic development of the sea urchin Paracentrotus lividus. Environ Toxicol Pharmacol. 2022 Oct;95:103956. doi: 10.1016/j.etap.2022.103956. Epub 2022 Aug 10. PMID: 35963553
5. Andreola F, Moliterni C, Quagliariello A, Scaldaferri F, Fidaleo M. Editorial: The Role of Microbiota in the Onset and Development of Intestine and Liver Diseases and Cancer: Molecular and Cell Mechanisms. Front Cell Dev Biol. 2022 Mar 9;10:852188. doi: 10.3389/fcell.2022.852188. PMID: 35356278; PMCID: PMC8959644.
6. Cavallucci V, Palucci I, Fidaleo M, Mercuri A, Masi L, Emoli V, Bianchetti G, Fiori ME, Bachrach G, Scaldaferri F, Maulucci G, Delogu G, Pani G. Proinflammatory and Cancer-Promoting Pathobiont Fusobacterium nucleatum Directly TargetsColorectal Cancer Stem Cells(2022) Biomolecules, 12 (9), art. no. 1256, .
7. Tredicine M, Camponeschi C, Pirolli D, Lucchini M, Valentini M, Geloso MC, Mirabella M, Fidaleo M, Righino B, Moliterni C, Giorda E, Rende M, De Rosa MC, Foti M, Constantin G, Ria F, Di Sante G. A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis. iScience. 2022 Jan 11;25(2):103763. doi: 10.1016/j.isci.2022.103763. PMID: 35128357; PMCID: PMC8804271.
8. Panzarini, E., Carata, E., Mariano, S., Tenuzzo, B. A., Tacconi, S., Fidaleo, M., & Dini, L. (2022). Plant and human health: the new era of biobased nanoscale systems. In Nanotechnology-Based Sustainable Alternatives for the Management of Plant Diseases (pp. 301-322). Elsevier.
9. Mariano, S., Tacconi, S., Fidaleo, M., & Rossi, M., Dini, L., (2021). Micro and Nanoplastics identification: Classic methods and innovative detection techniques. Frontiers in Toxicology, 3, 2.
10. Giudetti AM, Vergara D, Longo S, Friuli M, Eramo B, Tacconi S, Fidaleo M, Dini L, Romano A, Gaetani S. Oleoylethanolamide Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in High-Fat Diet-Fed Rats. Antioxidants (Basel). 2021 Aug 14;10(8):1289. doi: 10.3390/antiox10081289. PMID: 34439537; PMCID: PMC8389293.
11. Fidaleo, M.; Tacconi, S.; Sbarigia, C.; Passeri, D.; Rossi, M.; Tata, A.M.; Dini, L. Current Nanocarrier Strategies Improve Vitamin B12 Pharmacokinetics, Ameliorate Patients’ Lives, and Reduce Costs. Nanomaterials 2021, 11, 743. https://doi.org/10.3390/nano11030743
12. Petito, V., Fidaleo, M., Pani, G., Putignani, L., Gasbarrini, A., & Scaldaferri, F. (2020). Tumor necrosis factor-α and solute carrier family 22 member 4 gene polymorphisms as potential determinants of intestinal dysbiosis. Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 52(6), 691-693.
13. Cavallucci, V., Fidaleo, M., & Pani, G. (2020). Nutrients and neurogenesis: the emerging role of autophagy and gut microbiota. Current Opinion in Pharmacology, 50, 46-52.
14. Palombo, R., Frisone, P., Fidaleo, M., Mercatelli, N., Sette, C., & Paronetto, M. P. (2019). The Promoter-Associated Noncoding RNA pncCCND1_B Assembles a Protein–RNA Complex to Regulate Cyclin D1 Transcription in Ewing Sarcoma. Cancer research, 79(14), 3570-3582.
15. Passacantilli, I., Frisone, P., De Paola, E., Fidaleo, M., & Paronetto, M. P. (2017). hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells. Nucleic acids research, 45(21), 12270-12284.
16. Fidaleo, M*., Cavallucci, V*., & Pani, G. (2017). Nutrients, neurogenesis and brain ageing: from disease mechanisms to therapeutic opportunities. Biochemical pharmacology, 141, 63-76. (*equal contribution)
17. Cavallucci, V*., Fidaleo, M*., & Pani, G. (2016). Neural stem cells and nutrients: poised between quiescence and exhaustion. Trends in Endocrinology & Metabolism, 27(11), 756-769 (*equal contribution)
18. Fidaleo, M., De Paola, E., & Paronetto, M. P. (2016). The RNA helicase A in malignant transformation. Oncotarget, 7(19), 28711.
19. Ascione, F., Zuorro, A., Fidaleo, M., Lavecchia, R., Guido, S., & Caserta, S. (2016). Experimental Investigation of Honey as Wound Repair Enhancer by In Vitro Time-Lapse Microscopy. Chemical Engineering Transactions, 49, 259-264.
20. Fidaleo, M., Lavecchia, R., & Zuorro, A. (2015). Antibacterial and anti-quorum sensing activities of selected Italian honeys against antibiotic-resistant pathogens. OnLine Journal of Biological Sciences, 15(4), 236.
21. Fidaleo, M*., Svetoni, F*., Volpe, E., Miñana, B., Caporossi, D., & Paronetto, M. P. (2015). Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9. Oncotarget, 6(31), 31740 (*equal contribution)
22. Zuorro, A., Fidaleo, M., Fidaleo, M., & Lavecchia, R. (2014). Degradation and antibiotic activity reduction of chloramphenicol in aqueous solution by UV/H2O2 process. Journal of environmental management, 133, 302-308.
23. Fidaleo, M., Fanelli, F., Cerù, MP., & Moreno, S. (2014). Neuroprotective properties of peroxisome proliferator-activated receptor alpha (PPARα) and its lipid ligands. Current Medicinal Chemistry, 21(24), 2803-2821.
24. Fidaleo, M*., Fracassi, A., Zuorro, A., Lavecchia, R., Moreno, S., & Sartori, C. (2014). Cocoa protective effects against abnormal fat storage and oxidative stress induced by a high-fat diet involve PPARα signalling activation. Food & Function, 5(11), 2931-2939. (* corresponding author)
25. Fidaleo, M., Zuorro, A., & Lavecchia, R. (2013). Enhanced antibacterial and anti-quorum sensing activities of triclosan by complexation with modified β-cyclodextrins. World Journal of Microbiology and Biotechnology, 29(9), 1731-1736.
26. Fidaleo, M*., & Sartori, C. (2013). PPARα Signaling is Activated by Cocoa in Mouse Liver. Natural Product Communications, 8(5), 1934578X1300800507. (* corresponding author)
27. Fidaleo, M., Zuorro, A., & Lavecchia, R. (2011). Antimicrobial activity of some Italian honeys against pathogenic bacteria. CHEMICAL ENGINEERING, 24, 1015.
28. Fidaleo, M*., Arnauld, S*., Clémencet, M. C., Chevillard, G., Royer, M. C., De Bruycker, M., Wanders, RJ., Athias, A., Gresti, J., Clouet, P., Degrace, P., Kersten, S., Espeel, M., Latruffe, N., Nicolas-Francès, V., & Mandard, S. (2011). A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα-mediated upregulation of SREBP-2 target genes in the liver. Biochimie, 93(5), 876-891 (*equal contribution)
29. Zuorro, A., Fidaleo, M., & Lavecchia, R. (2010). Solubility enhancement and antibacterial activity of chloramphenicol included in modified β-cyclodextrins. Bull Korean Chem Soc, 31, 3460-3462.
30. Fidaleo, M*. (2010). Peroxisomes and peroxisomal disorders: the main facts. Experimental and toxicologic pathology, 62(6), 615-625. (* corresponding author)
31. Fidaleo, M., Zuorro, A., & Lavecchia, R. (2010). Methylglyoxal: a new weapon against staphylococcal wound infections?. Chemistry letters, 39(4), 322-323.
32. Fidaleo, M*. (2009). Human health risk assessment for peroxisome proliferators: more than 30 years of research. Experimental and Toxicologic Pathology, 61(3), 215-221. (* corresponding author)
33. Arnauld, S*., Fidaleo, M*., Clémencet, M. C., Chevillard, G., Athias, A., Gresti, J., Wanders, RJ., Latruffe, N., Nicolas-Franès, V., & Mandard, S. (2009). Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14, 643. Biochimie, 91(11-12), 1376-1386. (*equal contribution)
34. Fidaleo, M*., & Sartori, C. (2008). Administration of ciprofibrate to lactating mothers induces PPARα-signaling pathway in the liver and kidney of suckling rats. Experimental and Toxicologic Pathology, 60(1), 33-4. (* corresponding author)
35. Fidaleo, M*., Berardi, E., & Sartori, C. (2008). Differential modulation of PPARα and γ target gene expression in the liver and kidney of rats treated with aspirin. Experimental and Toxicologic Pathology, 59(6), 391-397 (* corresponding author)