LUDOVICA LASCHENA

PhD Student

PhD program:: XLI
email: ludovica.laschena@uniroma1.it

supervisor: Prof.ssa Valeria Panebianco

Research: development of an integrated diagnostic pathway for the early detection of clinically significant prostate cancer, combining prostate MRI, targeted biopsies, and spatial transcriptomics, with the aim of improving patient stratification and supporting personalized therapeutic decision-making

Education and Training
• Academic Year 2019/2020: Degree in Medicine and Surgery from Sapienza University of Rome. Final grade: 110/110 with honors (15/07/2020)
• 01/11/2021 – 30/10/2025: Residency in Radiology at Sapienza University of Rome. Final grade: 70/70 with honors (27/10/2025)
• 30/10/2025 – Present: Phd in Network Oncology and Precision Medicine at Sapienza University of Rome

Work Experience
• October 2020: Performed oro-nasopharyngeal swabs for SARS-CoV-2 detection at Poliambulatorio Analisi Cliniche Luisa and venous blood draws.
• October 2020 - November 2020: Performed oro-nasopharyngeal swabs for SARS-CoV-2 detection at the pedestrian Drive-in at Villa Betania.
• December 2020 - March 2022: Performed oro-nasopharyngeal swabs for SARS-CoV-2 detection at Fiumicino Airport Drive-in. Vaccination doctor at the Fiumicino and Porta di Roma Vaccination Hubs in collaboration with the Italian Red Cross.

Funding
2024: Awarded funding under the Scientific Research Call “Projects for Research Start-up – Type 1” for the research project titled: “Diffusion Weighted Imaging as Imaging Guide to MR-Directed Prostate Biopsies”

Personal Skills and Competences
Mother tongue: Italian
Other languages: English - Reading: B2, Writing: B2, Speaking: C1

Relational Skills
Effective communication - Empathy and clear interaction with colleagues and patients - Active listening and emotional support - Sensitivity to emotional and psychological needs

Organizational Skills
Teamwork in multidisciplinary teams - Flexibility and adaptability - Time management and prioritization Technical Skills - Proficient in medical imaging software such as PACS and RIS - Experience with some AI tools in radiology - Participation in radiological research and publication

Research Area Field
Uro-genital Imaging and Abdominal Imaging • MRI (prostate, bladder, kidneys) • Prostate targeted biopsies • CT (kidneys, post-processing) • Network Medicine in prostate cancer research

Scientific Affiliations
Italian Society of Medical and Interventional Radiology (SIRM)
• European Society of Radiology (ESR)
• European Society of Urogenital Radiology (ESUR)
Research project: PhD activity focused on the development of an integrated diagnostic pathway for the early detection of clinically significant prostate cancer, combining prostate MRI, targeted biopsies, and spatial transcriptomics, with the aim of improving patient stratification and supporting personalized therapeutic decision-making.

Research products

11573/1767213 - 2026 - Integrating Artificial Intelligence into Prostate MR Imaging: Technical Foundations, Clinical Applications, and Workflow Implications

Messina, Emanuele; Novelli, Simone; Laschena, Ludovica; Borrelli, Antonella; Mezzapesa, Francesca; De Giacomo, Luca; Bincoletto, Gaia; Messineo, Daniela; Bicchetti, Marco; Dehghanpour, Ailin; Pecoraro, Martina; Del Monte, Maurizio; Panebianco, Valeria - 01g Articolo di rassegna (Review)

paper: MAGNETIC RESONANCE IN MEDICAL SCIENCES (- Tokyo : Japanese Society for Magnetic Resonance in Medicine - Tokyo : Japan Society of Magnetic Resonance in Medicine) pp. - - issn: 1347-3182 - wos: WOS:001723774800001 (0) - scopus: (0)

11573/1767218 - 2026 - Multicentre validation of the PRECISE scoring system for prostate MRI during active surveillance

Giganti, Francesco; Leni, Riccardo; Wagaskar, Vinayak; Gandaglia, Giorgio; Barrett, Tristan; Panebianco, Valeria; Sanguedolce, Francesco; Van Der Hoeven, Erik Jrj; Ghai, Sangeet; Grummet, Jeremy; Gmeiner, Jasmin; Radtke, Jan Philipp; Ward, Ryan D.; Baroni, Ronaldo Hueb; Porpiglia, Francesco; Rivas, Juan Gomez; Zattoni, Fabio; Renard-Penna, Raphaële; Kesch, Claudia; Gatti, Marco; Schieda, Nicola; Ploussard, Guillaume; Lewis, Sara; Brembilla, Giorgio; Kastner, Christof; Messina, Emanuele; Tewari, Ash; Moore, Caroline M.; Valerio, Massimo; Stabile, Armando; Kasivisvanathan, Veeru; Null, Null; Freeman, Alex; Haider, Aiman; Englman, Cameron; Allen, Clare; Emberton, Mark; Dickinson, Louise; Fatterpekar, Monali; Pasat-Karasik, Cristina; Ratnani, Parita; Briganti, Alberto; Barletta, Francesco; Scuderi, Simone; Quarta, Leonardo; Montorsi, Francesco; Sanmugalingam, Nimalan; Sushentsev, Nikita; Caglic, Iztok; Lee, Kang Lung; Borrelli, Antonella; Laschena, Ludovica; Pecoraro, Martina; Dehghanpour, Ailin; Rakauskas, Arnas; Violi, Naik Vietti; Hernandez, Jonathan; Heetman, Joris G.; Finelli, Antonio; Pham, Tho; Rajwa, Pawel; Baltzer, Pascal; Schimmöller, Lars; Boschheidgen, Matthias; Purysko, Andrei S.; Coelho, Fernando Morbeck; Checcucci, Enrico; De La Parra, Irene; Crimì, Filippo; Hadaschik, Boris A. - 01a Articolo in rivista

paper: EUROPEAN RADIOLOGY (Heidelberg : Springer.) pp. - - issn: 1432-1084 - wos: WOS:001639169900002 (0) - scopus: (0)

11573/1760260 - 2026 - Artificial intelligence-assisted reading of non-contrast prostate MRI: application and concordance with expert interpretation in a screening population within the PROSA trial

Messina, Emanuele; Borrelli, Antonella; Mezzapesa, Francesca; Laschena, Ludovica; Lucciola, Sara; Novelli, Simone; Landini, Nicholas; Pecoraro, Martina; Sciarra, Alessandro; Santini, Daniele; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN RADIOLOGY (Heidelberg : Springer.) pp. - - issn: 1432-1084 - wos: (0) - scopus: (0)

11573/1767214 - 2026 - AI-assessed sarcopenia as an independent predictor of neoadjuvant chemotherapy outcomes in muscle-invasive bladder cancer

Borrelli, Antonella; Novelli, Simone; Messina, Emanuele; Laschena, Ludovica; Dehghanpour, Ailin; Mezzapesa, Francesca; Landini, Nicholas; Simone, Giuseppe; Muscaritoli, Maurizio; Panebianco, Valeria - 01a Articolo in rivista

paper: LA RADIOLOGIA MEDICA (Milano: Springer Verlag Italia) pp. - - issn: 1826-6983 - wos: (0) - scopus: 2-s2.0-105034887229 (0)

11573/1742622 - 2025 - Diagnostic accuracy and inter-reader agreement of the nacVI-RADS for bladder cancer treated with neoadjuvant chemotherapy. A prospective validation study

Dehghanpour, Ailin; Pecoraro, Martina; Messina, Emanuele; Laschena, Ludovica; Borrelli, Antonella; Novelli, Simone; Santini, Daniele; Simone, Giuseppe; Girometti, Rossano; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN RADIOLOGY (Heidelberg : Springer.) pp. 4016-4026 - issn: 1432-1084 - wos: WOS:001387766500001 (2) - scopus: 2-s2.0-85213839348 (6)

11573/1745850 - 2025 - Biparametric vs Multiparametric MRI for Prostate Cancer Diagnosis

Ng, Alexander B. C. D.; Asif, Aqua; Agarwal, Ridhi; Panebianco, Valeria; Girometti, Rossano; Ghai, Sangeet; Gómez-Gómez, Enrique; Budäus, Lars; Barrett, Tristan; Radtke, Jan Philipp; Kesch, Claudia; De Cobelli, Francesco; Pham, Tho; Taneja, Samir S.; Hu, Jim C.; Tewari, Ash; Rodríguez Cabello, Miguel Á.; Dias, Adriano B.; Mynderse, Lance A.; Borghi, Marcelo; Boesen, Lars; Singh, Paras; Renard-Penna, Raphaële; Leow, Jeffrey J.; Falkenbach, Fabian; Pecoraro, Martina; Giannarini, Gianluca; Perlis, Nathan; López-Ruiz, Daniel; Kastner, Christof; Schimmöller, Lars; Rossiter, Marimo; Nathan, Arjun; Khetrapal, Pramit; Chan, Vinson Wai-Shun; Haider, Aiman; Clarke, Caroline S.; Punwani, Shonit; Brew-Graves, Chris; Dickinson, Louise; Mitra, Anita; Brembilla, Giorgio; Margolis, Daniel J. A.; Takwoingi, Yemisi; Emberton, Mark; Allen, Clare; Giganti, Francesco; Moore, Caroline M.; Kasivisvanathan, Veeru; Null, Null; Borrelli, Antonella; Briganti, Alberto; Crestani, Alessandro; Sciarra, Alessandro; Evangelista, Alex; Freeman, Alex; Kirkham, Alex; Zlotta, Alexandre; Blanca Pedregosa, Ana; Bjartell, Anders; Ryan, Andrew; Tong, Angela; Warren, Anne; Andrews, Antonette; Finelli, Antonio; Ciardi, Antonio; Rannikko, Antti; Stabile, Armando; Villers, Arnauld; Platas Sancho, Arturo; Baring, Ashley; Roy, Ashoke; Issa, Balqiisa; Israël, Bas; Hadaschik, Boris A; Aulló Gonzalez, Carolina; English, Caroline L; Hung Lee, Chau; Zuiani, Chiara; Caris, Christien; Von Stempel, Conrad; Amate, Cristina; Yong, Daniel Zp; Rozze, Davide; Lomas, Derek J; Cannoletta, Donato; Wang Chang, Eileen; Messina, Emanuele; Zussino, Gaia; Antoch, Gerald; Gandaglia, Giorgio; Robert, Gregoire; Sauter, Guido; Thevarajah, Harini; Sorrell, Harriet; Mcbain, Hazel; Reis, Henning; Rios Pita, Hernando; Potyka, Ingrid; Caglic, Iztok; Collavino, Jeanlou; Theysohn, Jens; Grummet, Jeremy; Koshy, Jincy; Weng, Jing Yi (Jessica); Wilkinson, John; Van Egmond, Joke; Piper, Jon; Deeks, Jonathan; O'brien, Jonathan; Valero Rosa, José; Luis Sanz Miguelañez, Juan; Mesa Quesada, Juan; Jannusch, Kai; Corr, Kateri; Haines, Kenneth; Umutlu, Lale; Quarta, Leonardo; Casarotto, Letizia; Gimeno, Linda; Orecchia, Luca; Moretti, Lucas; Laschena, Ludovica; Drewes, Lukas; De Rooij, Maarten; Sanchez Ostos, Manuel; Bicchetti, Marco; Gatti, Marco; De Los Desamparados Esteban Peris, María; Volpacchio, Mariano; Prentice, Mark; Graefen, Markus; Soligo, Matteo; Boschheidgen, Matthias; Roethke, Matthias C; Del Monte, Maurizio; Singhera, Mausam; Fatterpekar, Monali; Al-Nader, Mulham; Kachanov, Mykyta; Shaida, Nadeem; Takahashi, Naoki; Fleshner, Neil; Muirhead, Nicola; Vasdev, Nikhil; Sanmugalingam, Nimalan; Nørgaard, Nis; Albers, Peter; Vicente, Pete; Incze, Peter; Ryan, Philip; Rouvier, Philippe; Mead, Phoebe; Charles Mozer, Pierre; De Visschere, Pieter; Viana, Publio Cesar Cavalcante; Jimenez, Rafael E; Novotta, Réka; Huang, Richard; O'sullivan, Richard; Karlin Jepsen, Rikke; Frese, Robert; Clow, Rosemary; Al-Monajjed, Rouvier; Lewis, Sara; Cashman, Sophia; Pizzolitto, Stefano; Lelie, Steven; Lindner, Sydney; Shah, Syed; Al-Hammouri, Tarek; González Sanchez, Teresa; Bathala, Tharakeswara; Van Der Kwast, Theodorus H; Reid, Thomas; Mcclure, Timothy; Maurer, Tobias; Peruzzi, Valeria; Løgager, Vibeke; Prabhu, Vinay; Wagaskar, Vinayak; Witjes, Wim - 01l Trial clinico

paper: JAMA (American Medical Association:515 North State Street:Chicago, IL 60610:(800)262-2350, (312)464-2518, EMAIL: ama-subs@ama-assn.org, INTERNET: http://www.ama-assn.org, Fax: (312)464-5600) pp. - - issn: 0098-7484 - wos: (0) - scopus: (0)

11573/1738666 - 2025 - Multiparametric MRI for Bladder Cancer: A Practical Approach to the Clinical Application of VI-RADS

Pecoraro, Martina; Cipollari, Stefano; Messina, Emanuele; Laschena, Ludovica; Dehghanpour, Ailin; Borrelli, Antonella; Del Giudice, Francesco; Muglia, Valdair Francisco; Vargas, Hebert Alberto; Panebianco, Valeria - 01g Articolo di rassegna (Review)

paper: RADIOLOGY (Radiological Society of North America:820 Jorie Boulevard:Oak Brook, IL 60523:(630)571-7873, EMAIL: subscrib@rsna.org, INTERNET: http://www.rsna.org, Fax: (630)571-7837) pp. - - issn: 0033-8419 - wos: WOS:001462320900021 (0) - scopus: 2-s2.0-86000264135 (8)

11573/1738673 - 2025 - In reply to the letter to editor by Paz‑Manrique et al. regarding “What the urologist needs to know before radical prostatectomy: MRI efective support to pre‑surgery planning”

Laschena, Ludovica; Messina, Emanuele; Flammia, Rocco Simone; Borrelli, Antonella; Novelli, Simone; Messineo, Daniela; Leonardo, Costantino; Sciarra, Alessandro; Panebianco, Valeria - 01b Commento, Erratum, Replica e simili

paper: LA RADIOLOGIA MEDICA (- Milano : Springer Verlag Italia -Turin Italy: Edizioni Minerva Medica) pp. 989-990 - issn: 0033-8362 - wos: WOS:001479518300001 (0) - scopus: 2-s2.0-105004354065 (0)

11573/1758977 - 2025 - Primary Noncontrast Magnetic Resonance Imaging for Prostate Cancer Screening: A Randomized Clinical Trial (PROSA)

Messina, Emanuele; Borrelli, Antonella; Sciarra, Alessandro; Laschena, Ludovica; Antonini, Debora; Shaholli, David; Magliocca, Fabio M.; Novelli, Simone; Santini, Daniele; La Torre, Giuseppe; Panebianco, Valeria - 01l Trial clinico

paper: EUROPEAN UROLOGY (Amsterdam: Elsevier Science Basel; New York: Karger, 1975-) pp. - - issn: 0302-2838 - wos: (0) - scopus: 2-s2.0-105025153525 (1)

11573/1681989 - 2024 - Prospective validation study of a novel integrated pathway based on clinical features, MRI biomarkers and microRNAs for early detection of prostate cancer

Pecoraro, Martina; Catanzaro, Giuseppina; Conte, Federica; Besharat, Zein Mersini; Messina, Emanuele; Laschena, Ludovica; Trocchianesi, Sofia; Splendiani, Elena; Sciarra, Alessandro; Catalano, Carlo; Paci, Paola; Ferretti, Elisabetta; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN UROLOGY ONCOLOGY ([Amsterdam]: European Association of Urology; Published by Elsevier B.V.) pp. - - issn: 2588-9311 - wos: WOS:001171264200001 (2) - scopus: 2-s2.0-85181477687 (3)

11573/1714413 - 2024 - What the urologist needs to know before radical prostatectomy: MRI effective support to pre-surgery planning

Laschena, Ludovica; Messina, Emanuele; Flammia, Rocco Simone; Borrelli, Antonella; Novelli, Simone; Messineo, Daniela; Leonardo, Costantino; Sciarra, Alessandro; Ciardi, Antonio; Catalano, Carlo; Panebianco, Valeria - 01a Articolo in rivista

paper: LA RADIOLOGIA MEDICA (Milano: Springer Verlag Italia) pp. 1048-1061 - issn: 1826-6983 - wos: WOS:001254108500001 (4) - scopus: 2-s2.0-85196823659 (5)

11573/1727810 - 2024 - Imaging assessment of prostate cancer recurrence: advances in detection of local and systemic relapse

Muglia, Valdair Francisco; Laschena, Ludovica; Pecoraro, Martina; De Lion Gouvea, Gabriel; Colli, Leandro Machado; Panebianco, Valeria - 01a Articolo in rivista

paper: ABDOMINAL RADIOLOGY ([Boston MA]: Springer US, 2016-) pp. - - issn: 2366-0058 - wos: WOS:001309934800004 (2) - scopus: 2-s2.0-85203518184 (2)

11573/1718965 - 2024 - MRI for risk stratification of muscle invasion by upper tract urothelial carcinoma: a feasibility study

Messina, Emanuele; Proietti, Flavia; Laschena, Ludovica; Flammia, Rocco Simone; Pecoraro, Martina; Cipollari, Stefano; Simone, Giuseppe; Catalano, Carlo; Leonardo, Costantino; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN RADIOLOGY EXPERIMENTAL (Springer) pp. - - issn: 2509-9280 - wos: WOS:001145314800001 (7) - scopus: 2-s2.0-85182704521 (8)

11573/1671704 - 2023 - Bridging the experience gap in prostate multiparametric magnetic resonance imaging using artificial intelligence: A prospective multi-reader comparison study on inter-reader agreement in PI-RADS v2.1, image quality and reporting time between novice and expert readers

Forookhi, Ali; Laschena, Ludovica; Pecoraro, Martina; Borrelli, Antonella; Massaro, Michele; Dehghanpour, Ailin; Cipollari, Stefano; Catalano, Carlo; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN JOURNAL OF RADIOLOGY (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114 -editore precedente: Georg Thieme, Stuttgart ; New York : Thieme, [c1981.) pp. - - issn: 0720-048X - wos: WOS:000992926300001 (19) - scopus: 2-s2.0-85148606990 (22)

11573/1678102 - 2023 - Low cancer yield in pi-rads 3 upgraded to 4 by dynamic contrast-enhanced mri. is it time to reconsider scoring categorization

Messina, Emanuele; Pecoraro, Martina; Laschena, Ludovica; Bicchetti, Marco; Proietti, Flavia; Ciardi, Antonio; Leonardo, Costantino; Sciarra, Alessandro; Girometti, Rossano; Catalano, Carlo; Panebianco, Valeria - 01a Articolo in rivista

paper: EUROPEAN RADIOLOGY (Heidelberg : Springer.) pp. - - issn: 1432-1084 - wos: WOS:001053188900065 (30) - scopus: 2-s2.0-85152420105 (27)

11573/1669327 - 2023 - Seeing is believing: state of the art Imaging of bladder cancer

Messina, Emanuele; Pecoraro, Martina; Pisciotti, Martina Lucia; Del Giudice, Francesco; Lucciola, Sara; Bicchetti, Marco; Laschena, Ludovica; Roberto, Michela; De Berardinis, Ettore; Franco, Giorgio; Panebianco, Valeria - 01a Articolo in rivista

paper: SEMINARS IN RADIATION ONCOLOGY (W B Saunders Company:Fulfillment Department, The Curtis Center, Independence Square West:Philadelphia, PA 19106:(800)654-2452, (215)238-7800, EMAIL: wbspcs@harcourt.com, INTERNET: http://elsevierhealth.com, Fax: (215)238-6445) pp. 12-20 - issn: 1053-4296 - wos: WOS:000897773100002 (10) - scopus: 2-s2.0-85140955515 (13)

11573/1671719 - 2022 - Biparametric prostate MRI: impact of a deep learning-based software and of quantitative ADC values on the inter-reader agreement of experienced and inexperienced readers

Cipollari, Stefano; Pecoraro, Martina; Forookhi, Alì; Laschena, Ludovica; Bicchetti, Marco; Messina, Emanuele; Lucciola, Sara; Catalano, Carlo; Panebianco, Valeria - 01a Articolo in rivista

paper: LA RADIOLOGIA MEDICA (- Milano : Springer Verlag Italia -Turin Italy: Edizioni Minerva Medica) pp. 1245-1253 - issn: 0033-8362 - wos: WOS:000854862400003 (25) - scopus: 2-s2.0-85138162480 (22)