JACOPO DESIDERIO

Dottore di ricerca

ciclo: XXXIV


supervisore: Prof. Vito D'Andrea

Titolo della tesi: Linfoadenectomia guidata dall’imaging a fluorescenza mediante verde di indocianina e tecnologia near infrared nella gastrectomia robotica

Objectives: The objective of this study was verifying the feasibility and the role of a lymphadenectomy assisted by fluorescence imaging during robotic gastrectomy. Methods: This is an interventional prospective study. Inclusion criteria: cT1-cT3 and cN0-N+. Description: the day before surgery, the ICG was injected endoscopically into the submucosa around the tumor (0.83mg / mL, 0.3mL x 4-6). Each patient underwent a robotic total D2 gastrectomy. The lymph node stations were sent to the pathologist in different containers and further subdivided according to fluorescence. Results: Twenty patients were included in this study (Female=65%; mean age=73±9.56y). Among the pathological findings: mean tumor size=41.4mm±28.03; EGC was found in 45% of cases; 45% of patients had no Lns metastases (N0, no.=9), 20% had up to 2 metastic Lns (N1, no.=4), 5% 3 to 6 metastic Lns (N2, no.=1) and 30% a significant lymphnode spread with more than 7 metastatic Lns (N3a, no.=3; N3b no.=3). The 60% of patients showed an advanced stage of disease (II-III). No intraoperative major complications occurred. The total operative time was 324.61min±80.85, the EBL=103ml±102.83. The fluorescence detection rate was 100%. The total number of Lns analyzed was 1522Lns with a mean per patient=76.1Lns±25.41. The number of positive Lns for metastasis was 115Lns (mean=5.75Lns±9.11), consequently 1407Lns were free from disease. Total perigastric Lns=1155 (75.88%), while total extra-perigastric Lns=355 (24.12%). In the fluorescent tissue, 1349Lns were identified (88.63%). All the 115 metastatic Lns were fluorescent, while all Lns found in the non-fluorescent tissue areas were free from disease. Conclusions: Some advantages were found: easier detection of nodes in the adipose tissue and dissection in challenging anatomical sites, detection of small Lns that may escape at the normal view, checking the completeness of the lymphadenectomy at the end of the procedure.

Produzione scientifica

  • 11573/945345 - 2016 - Robotic double-loop reconstruction method following total gastrectomy (01a Articolo in rivista)
    PIRONI, DANIELE; SANTORO, ALBERTO; DESIDERIO, JACOPO
  • 11573/537239 - 2013 - Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. (01a Articolo in rivista)
    DESIDERIO, JACOPO; GUARINO, SALVATORE
  • 11573/949363 - 2017 - Robotic right hemicolectomy. Analysis of 108 consecutive procedures and multidimensional assessment of the learning curve (01a Articolo in rivista)
    DESIDERIO, JACOPO; GUARINO, SALVATORE; PALAZZINI, GIORGIO; D'ANDREA, VITO
  • 11573/523605 - 2013 - Effects of Laparoscopic Sleeve Gastrectomy in patients with morbid obesity and metabolic disorders (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; REDLER, ADRIANO
  • 11573/480868 - 2012 - Colonic explosion during treatment of radiotherapy complications in prostatic cancer (01a Articolo in rivista)
    DESIDERIO, JACOPO; DI ROCCO, GIORGIO; SANTORO, ALBERTO; REDLER, ADRIANO
  • 11573/354353 - 2011 - "THE TRATMENT OF HEPATOCELLULAR CARCINOMA:THE ROLE OF SURGERY IN A MULTIDISCIPLINARY APPROACH" (04b Atto di convegno in volume)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; DI ROCCO, GIORGIO
  • 11573/799537 - 2015 - Robotic pylorus-preserving pancreaticoduodenectomy. Technical considerations (01a Articolo in rivista)
    DESIDERIO, JACOPO; PIRONI, DANIELE; SANTORO, ALBERTO
  • 11573/690664 - 2014 - Robotic pancreaticoduodenectomy in a case of duodenal gastrointestinal stromal tumor (01a Articolo in rivista)
    DESIDERIO, JACOPO; D'ANDREA, VITO; SANTORO, ALBERTO
  • 11573/840136 - 2015 - Robotic total gastrectomy with intracorporeal robot-sewn anastomosis. A novel approach adopting the double-loop reconstruction method (01a Articolo in rivista)
    PIRONI, DANIELE; D'ANDREA, VITO; SANTORO, ALBERTO; DESIDERIO, JACOPO
  • 11573/570573 - 2014 - Laparoscopic versus open left colectomy in patients with sigmoid colon cancer: Prospective cohort study with long-term follow-up (01a Articolo in rivista)
    DESIDERIO, JACOPO; REDLER, ADRIANO; SANTORO, ALBERTO
  • 11573/1178027 - 2018 - Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy (01a Articolo in rivista)
    DESIDERIO, JACOPO; DI NARDO, DOMENICO; PALAZZINI, GIORGIO; D'ANDREA, VITO
  • 11573/463893 - 2012 - Gastric carcinosarcoma: A case report and review of the literature (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO
  • 11573/537241 - 2013 - Systematic review and meta-analysis of randomized clinical trials comparing single-incision versus conventional laparoscopic cholecystectomy. (01a Articolo in rivista)
    DESIDERIO, JACOPO; GUARINO, SALVATORE; SANTORO, ALBERTO
  • 11573/690858 - 2014 - Robotic rectal resection for cancer: A prospective cohort study to analyze surgical, clinical and oncological outcomes. (01a Articolo in rivista)
    DESIDERIO, JACOPO; FILIPPINI, ANGELO; D'ANDREA, VITO; SANTORO, ALBERTO
  • 11573/516599 - 2013 - Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors' experience. (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; REDLER, ADRIANO
  • 11573/982209 - 2017 - New totally intracorporeal reconstructive approach after robotic total gastrectomy. Technical details and short-term outcomes (01a Articolo in rivista)
    PALAZZINI, GIORGIO; D'ANDREA, VITO; DESIDERIO, JACOPO
  • 11573/951020 - 2017 - Minimally invasive surgery for gastric cancer. A comparison between robotic, laparoscopic and open surgery (01a Articolo in rivista)
    PALAZZINI, GIORGIO; D'ANDREA, VITO; DESIDERIO, JACOPO
  • 11573/443534 - 2011 - High tie versus low tie of the inferior mesenteric artery: a protocol for a systematic review (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; REDLER, ADRIANO
  • 11573/950987 - 2017 - Robotic total gastrectomy with intracorporeal robot-sewn esophagojejunal anastomosis: analysis of outcomes after adapting a new strategy for reconstruction. (04f Poster)
    PALAZZINI, GIORGIO; D'ANDREA, VITO; DESIDERIO, JACOPO
  • 11573/523602 - 2013 - Is-non-operative management safe and effective for all splenic blunt trauma? a systematic review (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; REDLER, ADRIANO
  • 11573/762186 - 2014 - Robotic distal pancreatectomy with or without preservation of spleen: a technical note (01a Articolo in rivista)
    DESIDERIO, JACOPO; DI ROCCO, GIORGIO; REDLER, ADRIANO; SANTORO, ALBERTO
  • 11573/530129 - 2013 - Current status of robotic bariatric surgery: a systematic review (01a Articolo in rivista)
    SANTORO, ALBERTO; GUARINO, SALVATORE; DESIDERIO, JACOPO; REDLER, ADRIANO
  • 11573/799549 - 2015 - Distal pancreatectomy with splenic preservation: a short-term outcome analysis of the Warshaw technique (01a Articolo in rivista)
    DESIDERIO, JACOPO; SANTORO, ALBERTO; PIRONI, DANIELE
  • 11573/769993 - 2014 - Case report Autoimmune pancreatitis: a case of difficult diagnosis (01a Articolo in rivista)
    SANTORO, ALBERTO; DESIDERIO, JACOPO
  • 11573/945340 - 2016 - Laparoscopic peritoneal lavage. Our experience and review of the literature (01g Articolo di rassegna (Review))
    DESIDERIO, JACOPO; PIRONI, DANIELE; SANTORO, ALBERTO
  • 11573/799520 - 2015 - Robotic versus laparoscopic approach in colonic resections for cancer and benign diseases. Systematic review and meta-analysis (01g Articolo di rassegna (Review))
    DESIDERIO, JACOPO; GUARINO, SALVATORE; SANTORO, ALBERTO; MINELLI, LILIANA
  • 11573/690860 - 2014 - Video Vignette: One-stage minimally invasive combined laparoscopic hepatic resection and robot-assisted right hemicolectomy and abdominoperineal resection (01a Articolo in rivista)
    DESIDERIO, JACOPO; REDLER, ADRIANO; SANTORO, ALBERTO
  • 11573/1381314 - 2020 - Enhanced recovery after surgery for gastric cancer (ERAS-GC). Optimizing patient outcome (01g Articolo di rassegna (Review))
    DESIDERIO, JACOPO; D'ANDREA, VITO
  • 11573/1356706 - 2019 - A protocol for cooperation to establish an International Gastric Cancer Unit (IGCU) (01a Articolo in rivista)
    DESIDERIO, JACOPO; D'ANDREA, VITO
  • 11573/1679576 - 2020 - Evaluation of appendicitis risk prediction models in adults with suspected appendicitis (01a Articolo in rivista)
    PODDA, GIAN MARCO; BOLTON, TESSA WENDY; ISSA, RAND EMAD AWAD; REZVANI, SEYEDALI; BARONIO, GIADA; LUCCHI, ANDREA; SAGNOTTA, ANDREA; CAMPAGNARO, THOMAS; GALLO, GAETANO; BIANCAFARINA, ALESSIA; PODDA, GIAN MARCO; SALAMONE, GIANCARLO; PEREIRA, JONAS PEDRO; LIMA, FRANCESCA MADDALENA; GARCEA, ALESSANDRO; MCARTHUR, IAN DOUGLAS; FIORI NASTRO, PAOLO; BHARGAVA, ANVITA; MAGRO, TIZIANA; MARSHALL, GARLAND; MARANGONI, GIOELE; MIRZA, SUSANNA; CIANCHI, FILIPPO; CAPELLI, PIERO; GUGLIELMI, ALESSANDRA; PIETRABISSA, ANTONIO; COLANGELO, ETTORE; CASTAGNOLI, GIUSEPPE; SALAMONE, GIANCARLO; BABILONI, FABIO; GARCEA, ALESSANDRO; JONES, AMELIA GWEN; JOHNSON, J KARL; MORGAN, RANDA MARIA; BROWN, LORI ANN; ISSA, RAND EMAD AWAD; ISMAIL, OMAR HABIB; WILLIAMS, CAROLYN S.; PATEL, NEEL; O'BRIEN, MAHON JAMES; AL MANSOUR, MONIR; JAIN, ARIHANT; WILLIAMS, JULIAN MARK; HUSSAIN, NASIR; ISLAM, SHAHIDUL; HUSSAIN, ALTAF; KAMAL, MARYAM; MILLER, JOSHUA BENJAMIN; TURNBULL, JUDITH ANNE; WILLIAMS, RICCARDO; BULL, CHRISTIAN; COSSU, FABRIZIO; VULCANO, CARMINE LUCIANO; BARONIO, GIADA; SEPE, LILIANA CARMELA; LA REGINA, GIUSEPPE; LUCCHI, ANDREA; CAMPAGNARO, THOMAS; LAZZARI, GIULIA; DESIDERIO, JACOPO; SAGNOTTA, ANDREA; VIVIANI, EMANUELE; PIU, FEDERICA; ANGELIERI, DANIELE; FALASCHI, FEDERICA; CIRILLO, BRUNO; POILLUCCI, GAETANO; PINNA, ELENA; DE LUCA, EUGENIA; VESCIO, GIOVANNI; D'AMBRA, LUCA; GENNAI, ANDREA; CERVELLERA, MONICA; BIANCAFARINA, ALESSIA; PROVENZA, GIUSEPPE; PODDA, GIAN MARCO; CASTAGNOLI, GIUSEPPE; GIRAUDO, GIANLUCA; ROMOLI, LETIZIA; RIBAUDO, MARIA CRISTINA; CARCOFORO, PAOLO; SALAMONE, GIANCARLO; LICARI, LESLIE CLAIRE; MELLA, YURI ALFONZO; STOICA, IONELA GEORGIANA; MURPHY, ANDREW ROBERT; MUNTEAN, ADRIAN; SANCHEZ, LORENZO RAONEL SIMON; DIAZ, MARTA ELENA ANGELA; ANSARI, SIDDIQUE AKBER; GRASSIA, MARIA GABRIELLA; DEPALMA, NORMA; SALAMONE, GIANCARLO
  • 11573/1338607 - 2015 - Can the measurement of amylase in drain after distal pancreatectomy predict post-operative pancreatic fistula? (01a Articolo in rivista)
    POLISTENA, ANDREA; DESIDERIO, JACOPO
  • 11573/1504220 - 2021 - Modified ypTNM Staging Classification for Gastric Cancer after Neoadjuvant Therapy: A Multi-Institutional Study (01a Articolo in rivista)
    DESIDERIO, JACOPO
  • 11573/1504328 - 2019 - Robotic total gastrectomy for gastric cancer in Italy: clinical and oncological results from the IMIGASTRIC database (04d Abstract in atti di convegno)
    DI NARDO, DOMENICO; DESIDERIO, JACOPO; EBERSPACHER, CHIARA; D'ANDREA, VITO; PALAZZINI, GIORGIO
  • 11573/1504305 - 2019 - Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy (04d Abstract in atti di convegno)
    DESIDERIO, JACOPO; DI NARDO, DOMENICO; D'ANDREA, VITO
  • 11573/1504290 - 2019 - A case matched analysis from the IMIGASTRIC database to compare robotic, laparoscopic and open (04d Abstract in atti di convegno)
    DI NARDO, DOMENICO; DESIDERIO, JACOPO; EBERSPACHER, CHIARA; PALAZZINI, GIORGIO
  • 11573/1529296 - 2021 - Gastrectomy for stage IV gastric cancer. A comparison of different treatment strategies from the SEER database (01a Articolo in rivista)
    DESIDERIO, JACOPO; SAGNOTTA, ANDREA; ANNIBALE, BRUNO; D'ANDREA, VITO
  • 11573/1504230 - 2020 - Multicenter validation study of the American Joint Commission on Cancer (8th Edition) for gastric cancer: Proposal for a simplified and improved TNM staging system (01a Articolo in rivista)
    DESIDERIO, JACOPO; LU, JING
  • 11573/864769 - 2016 - Analysis of long-term results after liver surgery for metastases from colorectal and non-colorectal tumors (01a Articolo in rivista)
    PIRONI, DANIELE; D'ANDREA, VITO; SANTORO, ALBERTO; DESIDERIO, JACOPO
  • 11573/1504319 - 2019 - Robotic gastrectomy compared with open surgery in western centers: a weighted analysis based on sites effect from the Imigastric database (04d Abstract in atti di convegno)
    DESIDERIO, JACOPO; DI NARDO, DOMENICO
  • 11573/1504297 - 2019 - A prospective trial comparing minimally invasive approaches and open surgery is needed in gastric cancer. Methodology from a study protocol (04d Abstract in atti di convegno)
    DI NARDO, DOMENICO; DESIDERIO, JACOPO; EBERSPACHER, CHIARA; PALAZZINI, GIORGIO
  • 11573/1671405 - 2023 - THE DUODENAL WINDOW APPROACH TO PANCREATODUODENECTOMY (01a Articolo in rivista)
    AVENIA, STEFANO; DESIDERIO, JACOPO; DI NARDO, DOMENICO; RANUCCI, MARIA CHIARA
  • 11573/1659861 - 2020 - Safety of hospital discharge before return of bowel function after elective colorectal surgery (01a Articolo in rivista)
    SAGNOTTA, ANDREA; PARINI, DIEGO; MARTIN, PETRA; LA TORRE, FILIPPO; COLANGELO, ETTORE; SAGNOTTA, ANDREA; DESIDERIO, JACOPO; LAPOLLA, PIERFRANCESCO; COLETTA, DIEGO; CIRILLO, BRUNO; DE TOMA, GIORGIO; GALLO, GAETANO; LICARI, LESLIE CLAIRE; CERRA, CATIA; PATEL, SANDESH KUMAR
  • 11573/1648194 - 2021 - Laparoscopic compared with open d2 gastrectomy on perioperative and long‐term, stage‐stratified oncological outcomes for gastric cancer. A propensity score‐matched analysis of the imigastric database. (01a Articolo in rivista)
    DESIDERIO, JACOPO; D'ANDREA, VITO
  • 11573/1671408 - 2022 - Incidental Neuroendocrine Tumor of the appendix: what better attitude in case of acute appendicitis? A case report and review of literature. (04f Poster)
    DI NARDO, DOMENICO; DESIDERIO, JACOPO; PALAZZINI, GIORGIO
  • 11573/537240 - 2013 - Intracorporeal versus extracorporeal anastomosis during laparoscopic right hemicolectomy - systematic review and meta-analysis. (01a Articolo in rivista)
    GUARINO, SALVATORE; DESIDERIO, JACOPO
  • 11573/480659 - 2012 - Total thyroidectomy with ultrasonic dissector for cancer: multicentric experience (01a Articolo in rivista)
    GUARINO, SALVATORE; DESIDERIO, JACOPO; SANTORO, ALBERTO; DE TOMA, GIORGIO
  • 11573/633220 - 2014 - Robotic right colectomy with intracorporeal anastomosis compared with laparoscopic right colectomy with extracorporeal and intracorporeal anastomosis: a retrospective multicentre study. (01a Articolo in rivista)
    GUARINO, SALVATORE; DESIDERIO, JACOPO

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