Hani S. El-Nezami

Professore associato

email: elnezami@hku.hk
telefono: +85261109527
edificio: Kadoorie Biological Sciences Building
stanza: S13

Academic qualifications:
- MAppSc, RMIT-University, Australia, 1994
- PhD, RMIT-University, Australia, 1999.

Previous academic positions held (with dates):
- Academy of Finland Senior Fellow (Health Council), 2005-2010 (resigned to take up the post at HKU)
- Senior Research Fellow, University of Kuopio, Kuopio, Finland, 2003-2005
- Post Doctoral Fellow, University of Kuopio, Kuopio, Finland, 1999- 2002

Present academic position:
- Associate Professor, University of Hong Kong, Faculty of Science, School of Biological Sciences
iv. Research interests: Gut Health, Gut Microbiota, Probiotics, Food Contaminants

Scientific publications in the last five years indexed in Scopus and/or Web of Science
1.Murphy LY Wan, Stephen J Forsythe, Hani El-Nezami. Probiotics interaction with foodborne pathogens. Critical Reviews in Food Science and Nutrition, 2018, In Press
2.Murphy LY Wan#, KH Ling#, Hani El-Nezami, MF Wang. Influence of dietary food components on gut health. Critical Reviews in Food Science and Nutrition, 2018. https://doi.org/10.1080/10408398.2018.1433629
3.Murphy Lam Yim Wan, Hani El-Nezami. Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy. Hepatobiliary Surgery and Nutrition, 2018, 7: 11–20.
4.Murphy LY Wan#, Zhijian Chen#, Nagendra P Shah, Hani El-Nezami. Effects of Lactobacillus rhamnosus GG and Escherichia coli Nissle 1917 cell-free supernatants on modulation of mucin and cytokine secretion on human intestinal epithelial HT29-MTX cells. Journal of Food Sciences, 2018. In Press
5.Murphy LY Wan#, KH Ling#, Hani El-Nezami, MF Wang. Oxyresveratrol protective effects against deoxynivalenol-induced intestinal barrier dysfunction and bacterial translocation on porcine intestinal epithelial IPEC-J2 cells. Journal of Food Bioactives, 2018, 1:116-123
6.Ka Yiu Yip, Murphy LY Wan, Alice ST Wong, Kenneth Korach, Hani El-Nezami. Combined Low-Dose Zearalenone and Aflatoxin B1 on Growth and Cell-Cycle Progression in Breast Cancer MCF-7 Cells. Toxicology Letters, 281:139-151, 2017
7.Wan MLY, KH Ling, Hani El-Nezami, MF Wang. 2018. Influence of dietary food components on gut health. Critical Reviews in Food Sciences and Nutrition, doi: 10.1080/10408398.2018.1433629
8.J Ou, J Teng, HS El-Nezami, M Wang. 2018. Impact of resveratrol, epicatechin and rosmarinic acid on fluorescent AGEs and cytotoxicity of cookies. J Functional Food, 40: 44-50.
9.Wan MLY, KH Ling, El-Nezami,H., MF Wang. 2018. Oxyresveratrol protective effects against deoxynivalenol-induced intestinal barrier dysfunction and bacterial translocation on porcine intestinal epithelial IPEC-J2 cells. Journal of Food Bioactives, 2018. Accepted.
10.Murphy Lam Yim Wan, Hani El-Nezami. Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy. Hepatobiliary Surgery and Nutrition, 2018, In Press.
11.Poon W.L., Alenius H., Ndika J., Fortino, Kolhinen V., Mesceriakovas A., Wang M.F., Greco D., Lahde A, Jokiniemi J., Lee JCY, El-Nezami H., and Piia Karisola., 2017. Nano-sized zinc oxide and silver, but not titanium dioxide, induce innate and adaptive immunity and antiviral response in differentiated THP-1 cells. Nanotoxicology, doi.org/10.1080/17435390.2017.1382600
12.Yan, S. C. A., Lau, W., Chan, W., Greiner, R., Ma, S.W., Kitts, D. D., and El-Nezami, H., 2017. Prenatal developmental toxicity in rats assessed after oral exposure to polyvinylpyrrolidone-coated-silver nanoparticles. Toxicology, [Under major revision].
13.So SSY, Wan MLY, El-Nezami H. Probiotics-mediated suppression of cancer. Curr. Opin. Oncol. 2017, 29(1):62-72.
14.Ka YY, Wan MLY, Wong AST, Korach, K. and El-Nezami H. Combined Low-Dose Zearalenone and Aflatoxin B1 on Growth and Cell-Cycle Progression in Breast Cancer MCF-7 Cells. Toxicology Letters. Toxicology letters 281, 139-151
15.Ni Y, Wong VH, Tai WC, Li J, Wong WY, Lee MM, Fong FL, El-Nezami H, Panagiotou
G. A metagenomic study of the preventive effect of Lactobacillus rhamnosus GG on intestinal polyp formation in ApcMin/+ mice. J. Appl. Microbiol, 2016 [Epub ahead of print]
16.Chan YK, El-Nezami H, Chen Y, Kinnunen K, Kirjavainen PK. Probiotic mixture VSL#3 reduce high fat diet induced vascular inflammation and atherosclerosis in ApoE−/− mice. AMB Express, 2016, 6(1):61.
17.Chan YK, Brar MS, Kirjavainen PK, Chen Y, Peng J, Li D, Leung FCC, El-Nezami H. High fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma A-FABP and cholesterol: a pilot study of high fat diet and its intervention with Lactobacillus rhamnosus GG (LGG) or telmisartan in ApoE mice. BMC Microbiol., 2016, 16:264.
18.Li J, Sung CYJ, Yueqiong Ni, Panagiotou G and El-Nezami H: Probiotic modulated gut microbiota suppresses hepatocellular carcinoma growth in mice. Proceedings National Academy of Sciences (PNAS), 2016 doi: 10.1073/pnas.1518189113
19.Fong FLY, Kirjavainen P, Wong VHY, El-Nezami H: Immunomodulatory effects of Lactobacillus rhamnosus GG (LGG)-derived soluble factors on antigen-presenting cells from healthy blood donors. Scientific Reports 2016, doi: 10.1038/srep22845.
20.Murphy L. Y. Wan, Paul C. Turner, Kevin J. Allen, Hani El-Nezami. Lactobacillus rhamnosus GG modulates intestinal mucosal barrier and inflammation in mice following combined dietary exposure to deoxynivalenol and zearalenone. J. Functional Foods 2016. 22:34-43
21.Murphy LY Wan, KH Ling, MF Wang, Hani El-Nezami. Green tea polyphenol epigallocatechin-3-gallate preserves intestinal epithelial barrier functions by preventing bacterial translocation at physiological concentrations. Molecular Nutrition and Food Research. 2016 DOI 10.1002/mnfr.201500992
22. KH Ling, Murphy LY Wan, Hani El-Nezami, MF Wang. Protective capacity of resveratrol, a red wine constituent polyphenol against deoxynivalenol-induced intestinal barrier dysfunction and bacterial translocation. Chem Res Toxicol 2016 DOI: 10.1021/acs.chemrestox.6b00001
23.Woo CSJ, and El-Nezami H: Maternal-Fetal Cancer Risk Assessment of Ochratoxin A during Pregnancy. Toxins 2016, doi:10.3390/toxins8040087
24.Monson, M, Settlage, R, Mendoza, K, Rawal, S, El-Nezami, H, Coulombe, R and Reed, K: Modulation of the spleen transcriptome in domestic turkey (Meleagris gallopavo) in response to aflatoxin B1 and probiotics. Immunogenetics 2015, 67(3): 163-178.
25. Woo CSJ, and El-Nezami H: Mycotoxins in Asia: is China in danger? QUAL ASSUR SAF CROP 2015, 7(1): 3-25.
26. Fong FLY., Kirjavainen P., Shah N., El-Nezami H.S: Mechanism of Action of Probiotic Bacteria on Intestinal and Systemic Immunities and Antigen Presenting Cells, International Reviews Immunology 2015
27.Fong FLY, Kirjavainen P., Wong V. H. Y., El-Nezami H.S: Immunomodulatory effects of Lactobacillus rhamnosus GG on dendritic cells, J Functional Foods 2015, 13:71-79



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