Giovanna Poce

Professore associato


email: giovanna.poce@uniroma1.it
telefono: +39 06 4991 3892
edificio: CU019
stanza: 202

Posizione Attuale Professore Associato (CHIM/08) Istruzione/formazione 10/03/2008, Dottorato di ricerca in Scienze Farmaceutiche, Facoltà di Farmacia, Sapienza Università di Roma 18/03/2004, Laurea in Chimica e Tecnologia Farmaceutiche, Facoltà di Farmacia, Sapienza Università di Roma Esperienze professionali 15/02/2021 - oggi, Professore Associato (CHIM/08), Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma 15/02/2019 - 14/02/2021, Ricercatore a Tempo Determinato B) (CHIM/08), Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma 01/10/2014 - 14/02/2019, Ricercatore a Tempo Determinato A) (CHIM/08), Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma 01/11/2007 - 30/09/2014, Post-doc, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma 03/08/2016 - 30/08/2016, Visiting Academic, Faculty of Health Sciences, University of Cape Town, South Africa. 20/10/2010 - 30/08/2012, Visiting Scientist, Department of Immunology and Infectious Diseases, Harvard School of Public Health, USA. 06/04/2009 - 30/10/2009, Academic Visitor, Department of Chemistry, Oxford University, UK. 06/12/2023, Abilitazione Scientifica Nazionale, Professore I fascia, 03/D1 CHIM/08 31/10/2018, Abilitazione Scientifica Nazionale, Professore II fascia, 03/D1 CHIM/08 Attività didattica 03/2015 - oggi, Titolare del corso Analisi dei Medicinali I (M-Z), Facoltà di Farmacia e Medicina, Sapienza Università di Roma 03/2021 - oggi, Titolare del corso Pharmaceutical Chemistry, CCL Bioinformatics, Sapienza Università di Roma Principali interessi di ricerca Design, synthesis and characterization of small molecules active against M. tuberculosis hitting novel targets: MmpL3, iron chelation, tryptophan biosynthetic pathway. Hit-to-Lead development. Design, synthesis and characterization of small molecule fluorophores as RNA mimics of green fluorescent protein for imaging purpose. BM212 drug target identification and validation: generation of resistant mutants, whole genome sequencing and development of assays that selectively access mycolates on the surface of M. smegmatis spheroplasts demonstrated that BM212 binds MmpL3 and inhibits flipping of mycolic acids across the inner membrane. PZP drug target identification and validation: generation of resistant mutants, whole genome sequencing, RNA extraction and quantitative RT-PCR, ESI-MS studies and UV-Vis titration of PZP with Fe2+ demonstrated that PZP enters mycobacterial cells and chelates Fe2+ and starves the bacteria for intracellular iron. Design, synthesis and characterization of small molecules active against Leishmania donovani. Comunicazioni a congresso/seminari Poce, G. Small molecules as enabling tools to advance antimicrobial research. Drug discovery & screening symposium from bench to drug discover, Institut Pasteur, Paris, France, December 7, 2023. (Keynote_Invited speaker) Poce, G. Simple Chemistries as Enabling Tool for Advancing TB and Cancer Research. Department of Chemistry, University of Cape Town, Cape Town, South Africa, August 24, 2016. (Seminar) Poce, G. Towards Tuberculosis Treatment with Next Generation BM635 Analogues. NPCF8, Parma, June 09-11, 2014. (Oral Communication) Poce, G. Towards Tuberculosis Treatment with Novel MmpL3 Inhibitors. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Perugia, Perugia, March 18, 2014. (Seminar) Poce, G. MmpL3 Inhibitors Enabling New Possibilities for TB Treatment. XXII National Meeting on Medicinal Chemistry, Rome, September 10-13, 2013. (Oral communication) Poce, G. BM212-Derived MmpL3 Inhibitors Enabling New Possibilities for the Treatment of TB. Tuberculosis Drug Development, Gordon Research Conference, Barga (LU), July 21-26, 2013. (Keynote_Invited speaker) Poce, G. Hit-to-Lead Development for a New Class of Anti-Mycobacterial Agents. Tres Cantos Open Lab Foundation, Tres Cantos, Spain, June 10, 2013. (Keynote_Invited speaker) Poce, G.; Porretta, G. C; De Logu, A.; De Rossi, E.; Rubin, E.J.; Ballel, L.; Botta, M.; Biava, M. 1,5-Diphenyl Pyrrolesas New Antimycobacterial Agents. Hit-to-lead Development and Target Validation. COST Action MeetingCM0801, Siena, May 30 – June 5, 2012. (Short oral communication) Poce, G. Identification of a New Chemical Series of Potent Antimycobacterial Compounds. XX National Meeting on Medicinal Chemistry, Abano Terme, September 12-16, 2010. (Oral communication) Biava, M.; Porretta, G.C.; Poce, G.; De Logu, A.; Manetti, F.; Botta, M. New Pyrrole Derivatives of BM212: a New Class of Antimycobacterial Agents. Design, Synthesis, Biological Evaluation and Study of Their Mode of Action. NPCFIII, Pisa, February 13-14, 2009. (Oral communication) Session Chairman: Session: Alternative Approaches to Target ID and Drug Discovery. Tuberculosis Drug Development, Gordon-Kenan Research Seminar, Barga (LU), July 20-21, 2013. Collaborazioni: - Prof Flaminia Catteruccia, Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, USA. - Prof Eric J. Rubin, Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, USA. - Prof Varpu Marjomäki, Department of Biological and Environmental Science, University of Jyväskylä, Finland. - Prof Sarah Butcher, Institute of Biotechnology, University of Helsinki, Finland. - Prof Musa Mhlanga, Department of Cell Biology, Radboud University, The Netherland. - Prof Kelly Chibale, Department of Chemistry, University of Cape Town, South Africa. - Dr Fabrice Agou, Department of Structural Biology and Chemistry, Institut Pasteur, France.

Produzione scientifica

11573/1716808 - 2024 - Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development
Appetecchia, Federico; Fabbrizi, Emanuele; Fiorentino, Francesco; Consalvi, Sara; Biava, Mariangela; Poce, Giovanna; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: (0) - scopus: (0)

11573/1711757 - 2024 - Amino Acid Biosynthesis Inhibitors in Tuberculosis Drug Discovery
Guida, Michela; Tammaro, Chiara; Quaranta, Miriana; Salvucci, Benedetta; Biava, Mariangela; Poce, Giovanna; Consalvi, Sara - 01g Articolo di rassegna (Review)
rivista: PHARMACEUTICS (Basel: MDPI, 2009-) pp. 1-36 - issn: 1999-4923 - wos: WOS:001257061500001 (0) - scopus: 2-s2.0-85197351471 (0)

11573/1720626 - 2024 - SAR Analysis of Novel Coxsackie virus A9 Capsid Binders
Tammaro, Chiara; Plavec, Zlatka; Myllymäki, Laura; Mitchell, Cristopher; Consalvi, Sara; Biava, Mariangela; Ciogli, Alessia; Domanska, Aušra; Leppilampi, Valtteri; Buckner, Cienna; Manetto, Simone; Sciò, Pietro; Coluccia, Antonio; Laajala, Mira; Dondio, Giulio M; Bigogno, Chiara; Marjomäki, Varpu; Butcher, Sarah J; Poce, Giovanna - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. - - issn: 0022-2623 - wos: WOS:001315707100001 (0) - scopus: (0)

11573/1668341 - 2023 - Tannin microcapsules for synergy-enhanced sunscreen formulations
Alfonsi, E.; Lange, H.; Zongo, L.; Poce, G.; Sgarzi, M.; Crestini, C. - 01a Articolo in rivista
rivista: INDUSTRIAL CROPS AND PRODUCTS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 116105- - issn: 0926-6690 - wos: WOS:001029319300001 (1) - scopus: 2-s2.0-85143868314 (1)

11573/1675540 - 2023 - Antiviral Mechanisms of N-Phenyl Benzamides on Coxsackie Virus A9
Laajala, Mira; Kalander, Kerttu; Consalvi, Sara; Sheik Amamuddy, Olivier; Tastan Bishop, Özlem; Biava, Mariangela; Poce, Giovanna; Marjomäki, Varpu - 01a Articolo in rivista
rivista: PHARMACEUTICS (Basel: MDPI, 2009-) pp. - - issn: 1999-4923 - wos: WOS:000957987000001 (2) - scopus: 2-s2.0-85151320878 (1)

11573/1668339 - 2023 - Direct-Acting Antivirals and Host-Targeting Approaches against Enterovirus B Infections: Recent Advances
Tammaro, Chiara; Guida, Michela; Appetecchia, Federico; Biava, Mariangela; Consalvi, Sara; Poce, Giovanna - 01a Articolo in rivista
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 203- - issn: 1424-8247 - wos: WOS:000940922000001 (7) - scopus: 2-s2.0-85148952319 (6)

11573/1620087 - 2022 - Malaria transmission blocking compounds: a patent review
Consalvi, Sara; Tammaro, Chiara; Appetecchia, Federico; Biava, Mariangela; Poce, Giovanna - 01a Articolo in rivista
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1-18 - issn: 1354-3776 - wos: WOS:000767678000001 (7) - scopus: 2-s2.0-85126475360 (7)

11573/1655508 - 2022 - Nano-based drug delivery systems of potent MmpL3 inhibitors for tuberculosis treatment
Hanieh, P. N.; Consalvi, S.; Forte, J.; Cabiddu, G.; De Logu, A.; Poce, G.; Rinaldi, F.; Biava, M.; Carafa, M.; Marianecci, C. - 01a Articolo in rivista
rivista: PHARMACEUTICS (Basel: MDPI, 2009-) pp. 1-13 - issn: 1999-4923 - wos: WOS:000774333800001 (6) - scopus: 2-s2.0-85126452255 (6)

11573/1335786 - 2021 - Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy
Aiello, Paola; Consalvi, Sara; Poce, Giovanna; Raguzzini, Anna; Toti, Elisabetta; Palmery, Maura; Biava, Mariangela; Bernardi, Marco; Kamale, Mohammad A.; Perry, George; Peluso, Ilaria - 01g Articolo di rassegna (Review)
rivista: SEMINARS IN CANCER BIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 150-165 - issn: 1044-579X - wos: WOS:000631703400011 (71) - scopus: 2-s2.0-85071626772 (79)

11573/1614886 - 2021 - A novel class of dual-acting DCH-CORMs counteracts oxidative stress-induced inflammation in human primary tenocytes
Appetecchia, F.; Consalvi, S.; Berrino, E.; Gallorini, M.; Granese, A.; Campestre, C.; Carradori, S.; Biava, M.; Poce, G. - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. - - issn: 2076-3921 - wos: WOS:000728018500001 (5) - scopus: 2-s2.0-85119177792 (6)

11573/1487147 - 2021 - Therapeutic potential for coxibs-nitric oxide releasing hybrids in cystic fibrosis
Consalvi, S.; Poce, G.; Ghelardini, C.; Di Cesare Mannelli, L.; Patrignani, P.; Bruno, A.; Anzini, M.; Calderone, V.; Martelli, A.; Testai, L.; Giordani, A.; Biava, M. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 112983- - issn: 0223-5234 - wos: WOS:000604903800029 (4) - scopus: 2-s2.0-85096376603 (5)

11573/1614881 - 2021 - 6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis
Consalvi, S.; Venditti, G.; Zhu, J.; Boshoff, H. I.; Arora, K.; De Logu, A.; Ioerger, T. R.; Rubin, E. J.; Biava, M.; Poce, G. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000703119000027 (2) - scopus: 2-s2.0-85114741985 (2)

11573/1462744 - 2020 - Sar analysis of small molecules interfering with energy-metabolism in mycobacterium tuberculosis
Appetecchia, F.; Consalvi, S.; Scarpecci, C.; Biava, M.; Poce, G. - 01a Articolo in rivista
rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-33 - issn: 1424-8247 - wos: WOS:000580832600001 (10) - scopus: 2-s2.0-85092679912 (12)

11573/1493983 - 2020 - Overcoming drug resistance in TB: an update
Consalvi, S.; Poce, G.; Scarpecci, C.; Biava, M. - 01m Editorial/Introduzione in rivista
rivista: FUTURE MICROBIOLOGY (London : Future Medicine, 2006-.) pp. 1607-1609 - issn: 1746-0913 - wos: WOS:000591446300001 (1) - scopus: 2-s2.0-85097964343 (1)

11573/1334361 - 2019 - Mycobacterial tryptophan biosynthesis: a promising target for tuberculosis drug development?
Consalvi, Sara; Scarpecci, Cristina; Biava, Mariangela; Poce, Giovanna - 01g Articolo di rassegna (Review)
rivista: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (Oxford: Pergamon, Amsterdam the Netherlands: Elsevier) pp. 126731- - issn: 0960-894X - wos: WOS:000495112100015 (11) - scopus: 2-s2.0-85074070157 (11)

11573/1307478 - 2019 - Novel therapies for glaucoma: a patent review (2013-2019)
Guglielmi, Paolo; Carradori, Simone; Campestre, Cristina; Poce, Giovanna - 01g Articolo di rassegna (Review)
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 769-780 - issn: 1354-3776 - wos: WOS:000480502600001 (22) - scopus: 2-s2.0-85070821891 (27)

11573/1334375 - 2019 - Novel pyrazole-containing compounds active against mycobacterium tuberculosis
Poce, Giovanna; Consalvi, Sara; Venditti, Giulia; Alfonso, Salvatore; Desideri, Nicoletta; Fernandez-Menendez, Raquel; Bates, Robert H.; Ballell, Lluis; Barros Aguirre, David; Rullas, Joaquin; De Logu, Alessandro; Gardner, Michelle; Ioerger, Thomas R.; Rubin, Eric J.; Biava, Mariangela - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 1423-1429 - issn: 1948-5875 - wos: WOS:000490355900009 (37) - scopus: 2-s2.0-85073024402 (37)

11573/1655529 - 2019 - Development of MmpL3 inhibitors for tuberculosis treatment
Poce, Giovanna; Consalvi, Sara; Venditti, Giulia; Scarpecci, Cristina; Biava, Mariangela - 02a Capitolo o Articolo
libro: Medicinal Chemistry approaches to tuberculosis and trypanosomiasis - (978-0-12-817556-9)

11573/1334385 - 2019 - Chocolate consumers and lymphocyte-to-monocyte ratio: a working hypothesis from a preliminary report of a pilot study in celiac subjects
Raguzzini, A; Poce, G; Consalvi, S; Toti, E; Palmacci, F; Biava, M; Peluso, I - 01a Articolo in rivista
rivista: ANTIOXIDANTS (Basel: MDPI) pp. - - issn: 2076-3921 - wos: WOS:000500759900023 (4) - scopus: 2-s2.0-85073539054 (4)

11573/1191296 - 2018 - Stimuli-responsive tannin–feIII hybrid microcapsules demonstrated by the active release of an anti-tuberculosis agent
Bartzoka, Elisavet D.; Lange, Heiko; Poce, Giovanna; Crestini, Claudia - 01a Articolo in rivista
rivista: CHEMSUSCHEM (WEINHEIM, GERMANY: WILEY-V C H VERLAG GMBH) pp. 3975-3991 - issn: 1864-5631 - wos: WOS:000451061000015 (20) - scopus: 2-s2.0-85055454631 (20)

11573/1071677 - 2018 - In vivo potent BM635 analogue with improved drug-like properties
Poce, Giovanna; Cocozza, Martina; Alfonso, Salvatore; Consalvi, Sara; Venditti, Giulia; Fernandez-Menendez, Raquel; Bates, Robert H.; Barros Aguirre, David; Ballell, Lluis; De Logu, Alessandro; Vistoli, Giulio; Biava, Mariangela - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 539-550 - issn: 0223-5234 - wos: WOS:000425198200041 (21) - scopus: 2-s2.0-85040337865 (23)

11573/957091 - 2017 - Pharmaceutical salt of BM635 with improved bioavailability
Poce, Giovanna; Consalvi, Sara; Cocozza, Martina; Fernandez Menendez, Raquel; Bates, Robert H.; Ortega Muro, Fátima; Barros Aguirre, David; Ballell, Lluis; Biava, Mariangela - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (Amsterdam Netherlands: Elsevier BV) pp. 17-23 - issn: 0928-0987 - wos: WOS:000394474200003 (10) - scopus: 2-s2.0-85004187448 (10)

11573/957084 - 2017 - 1,5-Diarylpyrroles as potent antitubercular and anti-inflammatory agents
Venditti, Giulia; Poce, Giovanna; Consalvi, Sara; Biava, Mariangela - 01a Articolo in rivista
rivista: CHEMISTRY OF HETEROCYCLIC COMPOUNDS (Consultants Bureau:A Division of Plenum Publishing Corporation, 233 Spring Street, Sixth Floor:New York, NY 10013:(800)221-9369, (212)620-8082, Fax: (212)463-0742) pp. 281-291 - issn: 0009-3122 - wos: WOS:000400545300005 (4) - scopus: 2-s2.0-85018288338 (5)

11573/1071674 - 2017 - MmpL3 is the flippase for mycolic acids in mycobacteria
Xu, Zhujun; Meshcheryakov, Vladimir A.; Poce, Giovanna; Chng, Shu-Sin - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 7993-7998 - issn: 0027-8424 - wos: WOS:000406189900070 (138) - scopus: 2-s2.0-85025640419 (142)

11573/891076 - 2016 - A series of COX-2 inhibitors endowed with NO-releasing properties: synthesis, biological evaluation, and docking analysis
Consalvi, Sara; Poce, Giovanna; Ragno, Rino; Sabatino, Manuela; Lamotta, Concettina; Sartini, Stefania; Calderone, Vincenzo; Martelli, Alma; Ghelardini, Carla; Dicesaremannelli, Lorenzo; Biava, Mariangela - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1804-1811 - issn: 1860-7179 - wos: WOS:000383579700016 (5) - scopus: 2-s2.0-84983288442 (7)

11573/869500 - 2016 - Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
Di Capua, Angela; Sticozzi, Claudia; Brogi, Simone; Brindisi, Margherita; Cappelli, Andrea; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Valacchi, Giuseppe; Giorgi, Gianluca; Giordani, Antonio; Poce, Giovanna; Biava, Mariangela; Anzini, Maurizio - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 99-106 - issn: 0223-5234 - wos: WOS:000375634400009 (27) - scopus: 2-s2.0-84953931791 (30)

11573/1191315 - 2016 - MmpL3 inhibitors: diverse chemical scaffolds inhibit the same target
Poce, Giovanna; Consalvi, Sara; Biava, Mariangela - 01a Articolo in rivista
rivista: MINI-REVIEWS IN MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 1274-1283 - issn: 1389-5575 - wos: WOS:000385572900002 (24) - scopus: 2-s2.0-84991396425 (28)

11573/870679 - 2016 - Novel inhibitors of Mycobacterium tuberculosis tryptophan biosynthetic pathway to treat tuberculosis
Venditti, Giulia; Consalvi, Sara; Helena, Boshoff; Biava, Mariangela; Poce, Giovanna - 04f Poster
congresso: VI EWDSy (European Workshop in Drug Synthesis) (Siena, Italia)

11573/1668504 - 2015 - Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors
Consalvi, Sara; Alfonso, Salvatore; Di Capua, Angela; Poce, Giovanna; Pirolli, Adele; Sabatino, Manuela; Ragno, Rino; Anzini, Maurizio; Sartini, Stefania; La Motta, Concettina; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Biava, Mariangela - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY ([Oxford]: Elsevier.) pp. 810-820 - issn: 1464-3391 - wos: WOS:000349083100018 (22) - scopus: 2-s2.0-84922322412 (22)

11573/869416 - 2015 - COX inhibitors: a patent review (2011 - 2014)
Consalvi, Sara; Biava, Mariangela; Poce, Giovanna - 01a Articolo in rivista
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1357-1371 - issn: 1354-3776 - wos: WOS:000366526700001 (33) - scopus: 2-s2.0-84949780684 (33)

11573/781378 - 2015 - A novel antimycobacterial compound acts as an intracellular iron chelator
Dragset Marte, S; Poce, Giovanna; Alfonso, Salvatore; Padilla Benavides, T; Ioerger, T. R.; Kaneko, T; Sacchettini, Jc; Biava, Mariangela; Parish, T; Argüello, Jm; Steigedal, M; Rubin, Ej - 01a Articolo in rivista
rivista: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 2256-2264 - issn: 0066-4804 - wos: WOS:000354993700051 (35) - scopus: 2-s2.0-84928905358 (34)

11573/781382 - 2015 - Activity of lipophilic and hydrophilic drugs against dormant and replicating mycobacterium tuberculosis
Piccaro, G; Poce, Giovanna; Biava, Mariangela; Giannoni, F; Fattorini, L. - 01a Articolo in rivista
rivista: JOURNAL OF ANTIBIOTICS (Japan Antibiotics Research Association:2-20-8 Kamiosaki Shinagawa-ku, Tokyo 141-0021 Japan:011 81 3 34910181, EMAIL: gakkyo@antibotics.or.jp, INTERNET: http://www.anibotics.or.jp, Fax: 011 81 34910179) pp. 711-714 - issn: 0021-8820 - wos: WOS:000365832300010 (52) - scopus: 2-s2.0-84948651608 (57)

11573/869374 - 2015 - Overcoming drug resistance for tuberculosis
Poce, Giovanna; Biava, Mariangela - 01a Articolo in rivista
rivista: FUTURE MICROBIOLOGY (London : Future Medicine, 2006-.) pp. 1735-1741 - issn: 1746-0913 - wos: WOS:000365746000005 (8) - scopus: 2-s2.0-84948137710 (9)

11573/540514 - 2014 - Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors
Biava, Mariangela; Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Consalvi, Sara; Angela Di, Capua; Vincenzo, Calderone; Alma, Martelli; Lara, Testai; Lidia, Sautebin; Antonietta, Rossi; Carla, Ghelardini; Lorenzo Di Cesare, Mannelli; Antonio, Giordani; Stefano, Persiani; Milena, Colovic; Melania, Dovizio; Paola, Patrignani; Maurizio, Anzini - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 772-786 - issn: 0968-0896 - wos: WOS:000329576400011 (25) - scopus: 2-s2.0-84892370910 (26)

11573/639185 - 2014 - SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development
Poce, Giovanna; Cocozza, Martina; Consalvi, Sara; Biava, Mariangela - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 335-351 - issn: 0223-5234 - wos: WOS:000343781800031 (45) - scopus: 2-s2.0-84906997561 (49)

11573/515578 - 2013 - Novel Analgesic/Anti-inflammatory Agents: 1,5-Diarylpyrrole Nitro-oxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors
Anzini, M.; Di Capua, A.; Valenti, S.; Brogi, S.; Rovin, M.; Giuliani, G.; Cappelli, A.; Vomero, S.; Chiasserini, L.; Saga, A.; Poce, Giovanna; Giorgi, G.; Calderone, V.; Martelli, A.; Testai, L.; Sautebin, L.; Rossi, A.; Papa, G.; Ghelardini, C.; Di Cesare Mannelli, L.; Benetti, V.; Giordani, A.; Anzellotti, P.; Dovizio, M.; Patrignani, P.; Biava, Mariangela - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3191-3206 - issn: 0022-2623 - wos: WOS:000318211100005 (45) - scopus: 2-s2.0-84876827778 (47)

11573/523394 - 2013 - Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography
Baiocco, P.; Poce, Giovanna; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; Colotti, G.; Biava, Mariangela; Moraca, F.; Botta, M.; Yardley, V.; Fiorillo, A.; Lantella, A.; Malatesta, Francesco; Ilari, Andrea - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1175-1183 - issn: 1860-7179 - wos: WOS:000320928400012 (57) - scopus: 2-s2.0-84879786172 (61)

11573/516096 - 2013 - A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity
Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; Consalvi, Sara; L., Sautebin; S., Pace; A., Rossi; C., Ghelardini; L., Di Cesare Mannelli; S., Schenone; A., Giordani; L., Di Francesco; P., Patrignani; Biava, Mariangela - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY ([Oxford]: Elsevier.) pp. 3695-3701 - issn: 1464-3391 - wos: WOS:000320347100007 (83) - scopus: 2-s2.0-84878612651 (88)

11573/526248 - 2013 - The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and endothelial dysfunction
Martelli, A; Testai, L; Anzini, M; Cappelli, A; Di Capua, A; Biava, Mariangela; Poce, Giovanna; Consalvi, Sara; Giordani, A; Caselli, G; Rovati, L; Ghelardini, C; Patrignani, P; Sautebin, L; Breschi, Mc; Calderone, V. - 01a Articolo in rivista
rivista: PHARMACOLOGICAL RESEARCH (Attuale:ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 24-28 OVAL RD, LONDON, ENGLAND, NW1 7DX Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 1-9 - issn: 1043-6618 - wos: WOS:000328874100001 (22) - scopus: 2-s2.0-84886005479 (25)

11573/515576 - 2013 - Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection
Poce, Giovanna; H. R., Bates; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; L., Ballel; Joaquin, Rullas; Alessandro De, Logu; Emanuela, Agus; Valentina La, Rosa; Maria Rosalia, Pasca; Edda De, Rossi; Baojie, Wae; S. J., Franzblau; Fabrizio, Manetti; Maurizio, Botta; Biava, Mariangela - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e56980-e56980 - issn: 1932-6203 - wos: WOS:000315186000063 (91) - scopus: 2-s2.0-84874297088 (97)

11573/492770 - 2012 - New 1,5 diarylpyrrole derivatives as antimycobacterial agents: Design, synthesis, biological evaluation and study of their mode of action
Alfonso, Salvatore; Poce, Giovanna; Porretta, Giulio Cesare; Battilocchio, Claudio; Rubin, E. J.; De Rossi, E.; De Logu, A.; Franzblau, S. C.; Botta, M.; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: NPCF6 (Riccione)

11573/490950 - 2012 - Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme
Biava, Mariangela; Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; Consalvi, Sara; Vincenzo, Calderone; Alma, Martelli; Lara, Testai; Carla, Ghelardini; Lorenzo Di Cesare, Mannelli; Lidia, Sautebin; Antonietta, Rossi; Antonio, Giordani; Paola, Patrignani; Maurizio, Anzini - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 287-298 - issn: 0223-5234 - wos: WOS:000312745100029 (14) - scopus: 2-s2.0-84868249710 (16)

11573/492768 - 2012 - New Heterocyclic Compounds Targeting Trypanothyione Metabolism in Leishmania Parasites
Biava, Mariangela; Cocozza, Martina; Poce, Giovanna; Alfonso, Salvatore; Battilocchio, Claudio; Colotti, G.; Malatesta, F.; Baiocco, P.; Ilari, Andrea - 04d Abstract in atti di convegno
congresso: NPCF6 (Riccione)

11573/492764 - 2012 - New Pyrrole Derivatives as Anti-inflammatory and Analgesic Agents: Design, Synthesis and Biological Evaluation
Biava, Mariangela; Consalvi, Sara; Poce, Giovanna; Battilocchio, Claudio; Alfonso, Salvatore; Ghelardini, C.; Sautebin, L. - 04a Atto di comunicazione a congresso
congresso: NPCF6 (Riccione)

11573/492117 - 2012 - Analogs of BM 212: a new chemical class of antimycobacterial agents acting upon a new target
Biava, Mariangela; Poce, Giovanna; Porretta, Giulio Cesare; Alfonso, Salvatore; Cocozza, Martina; De Logu, A; De Rossi, E; Ballel, L; Franzblau, S; Rubin E., J; Botta, M. - 04a Atto di comunicazione a congresso
congresso: 21st National Meeting on Medicinal Chemistry (Palermo)

11573/492120 - 2012 - Identification of a new chemical class of potent antimycobacterial compounds derived from BM 212: design, synthesis, biological evaluation and study of their mode of action.
Biava, Mariangela; Poce, Giovanna; Porretta, Giulio Cesare; Alfonso, Salvatore; De Logu, A; De Rossi, E; Ballel, L; Franzblau, S; Manetti, ; Rubin, Ej; Botta, M. - 04a Atto di comunicazione a congresso
congresso: XXIInd International Symposium on Medicinal Chemistry (EFMC-ISMC) (Berlino, Germania)

11573/509516 - 2012 - New 1,5-diphenyl pyrrole derivatives as anti-inflammatory COX-2 selective compounds and their use as potential antitumoral agents.
Consalvi, Sara; Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; M., Anzini; L., Sautebin; C., Ghelardini; A., Giordani; P., Patrignani; V., Calderone; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: IV European Workshop in Drug Synthesis (Siena)

11573/492772 - 2012 - 1,5-Diphenyl pyrroles as new antimycobacterial agents. Hit-to-lead development and target validation, New drugs for neglected diseases
Poce, Giovanna; Porretta, Giulio Cesare; De Logu, A; De Rossi, A; Rubin, Ej; Ballel, L; Botta, M; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: , CM0801 – (Siena,)

11573/434001 - 2012 - MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212
V., La Rosa; Poce, Giovanna; J., Ortiz Canseco; S., Buroni; M. R., Pasca; Biava, Mariangela; R. M., Raju; Porretta, Giulio Cesare; Alfonso, Salvatore; C., Battilocchio; B., Javid; F., Sorrentino; T. R., Ioerger; J. C., Sacchettini; F., Manetti; M., Botta; A., De Logu; E. J., Rubin - 01a Articolo in rivista
rivista: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 324-331 - issn: 0066-4804 - wos: WOS:000298404900040 (186) - scopus: 2-s2.0-84455173193 (200)

11573/492740 - 2011 - Pyrrole-based selective COX-2 inhibiting nitric oxide donors: synthesis, in vitro and in vivo evaluation
Battilocchio, Claudio; Porretta, Giulio Cesare; Poce, Giovanna; Alfonso, Salvatore; Calderone, V.; Sautebin, L.; Ghelardini, C.; Giordani, A.; Anzini, M.; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: 5° Meeting NPCF (Trieste)
libro: 5° Meeting NUOVE PROSPETTIVE IN CHIMICA FARMACEUTICA - ()

11573/492752 - 2011 - New Pyrrole-based selective COX-2 inhibiting nitric oxide donors: synthesis, in vitro and in vivo evaluation
Battilocchio, Claudio; Porretta, Giulio Cesare; Poce, Giovanna; Alfonso, Salvatore; Giordani, A.; Sautebin, L.; Ghelardini, C.; Calderone, V.; Patrignani, P.; Anzini, M.; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: XXIV Congresso Naionale della Società Chimica Italiana (Lecce)

11573/492735 - 2011 - Synthesis and biological evaluation of new heterocyclic derivatives with potential antimycobacterial activity: systematic approach to lead compound optimization
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Alfonso, Salvatore; Battilocchio, Claudio; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: NPCF5 (Trieste)

11573/357725 - 2011 - Developing Pyrrole-Derived Antimycobacterial Agents: a Rational Lead Optimization Approach
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Alfonso, Salvatore; A., De Logu; Fabrizio, Manetti; Maurizio, Botta - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 593-599 - issn: 1860-7179 - wos: WOS:000288814900004 (43) - scopus: 2-s2.0-79953052237 (43)

11573/427797 - 2011 - Novel Analgesic/Anti-Inflammatory Agents: Diarylpyrrole Acetic Esters Endowed with Nitric Oxide Releasing Properties
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Alfonso, Salvatore; Michele, Rovini; Salvatore, Valenti; Gianluca, Giorgi; Vincenzo, Calderone; Alma, Martelli; Lara, Testai; Lidia, Sautebin; Antonietta, Rossi; Giuseppina, Papa; Carla, Ghelardini; Lorenzo Di Cesare, Mannelli; Antonio, Giordani; Paola, Anzellotti; Annalisa, Bruno; Paola, Patrignani; Anzini, - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 7759-7771 - issn: 0022-2623 - wos: WOS:000297001600003 (41) - scopus: 2-s2.0-81555218668 (42)

11573/356131 - 2011 - Enlarging the NSAIDs Family: Ether, Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Novel Anti-Inflammatory and Analgesic Agents
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Botta, M; Manetti, F; Rovini, M; Cappelli, A; Sautebin, L; Rossi, A; Pergola, C; Ghelardini, C; Galeotti, N; Makovec, F; Giordani, A; Anzellotti, P; Tacconelli, S; Patrignani, P; Anzini, M. - 01a Articolo in rivista
rivista: CURRENT MEDICINAL CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 1540-1554 - issn: 0929-8673 - wos: WOS:000289781000012 (13) - scopus: 2-s2.0-79955005080 (14)

11573/492747 - 2011 - BM212 targets MmpL3, Gordon Research Conference on Tuberculosis Drug Development
Poce, Giovanna; Biava, Mariangela; Porretta, Giulio Cesare; Battilocchio, Claudio; Alfonso, Salvatore; Botta, M.; Javid, B.; Sorrentino, F.; Ioerger, T. R.; Sacchettini, J. R.; Rubin, E. - 04a Atto di comunicazione a congresso
congresso: Gordon Research Conference on Tuberculosis Drug Development (Lucca (Barga))

11573/492710 - 2010 - New pyrrole derivatives of BM 212: a new class of antimycobacterial agents. Design, synthesis, biological evaluation and study of their mode of action
Biava, Mariangela; Porretta, G. C.; Poce, Giovanna; Alfonso, Salvatore; Battilocchio, Claudio; De Logu, A.; De Rossi, E.; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: COST Action Meeting CM0801 (Siena)
libro: CM0801-New Drugs For Neglected Diseases - ()

11573/492446 - 2010 - BM 579: a novel pyrrole derivative with improved antimycobacterial activity
Biava, Mariangela; Porretta, G. C.; Poce, Giovanna; Alfonso, Salvatore; Battilocchio, Claudio; De Logu, A.; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: NPCF4 (Santa Margherita di Pula (Ca))
libro: IV Meeting "Nuove Prospettive in Chimica Farmaceutica" - ()

11573/172075 - 2010 - 1,5-Diaryl-Pyrroles as New Generation of Anti-Inflammatory and Analgesic Agents: Design, Synthesis, in vitro and in vivo Evaluation
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Alfonso, S; Battilocchio, Claudio; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: NPCF IV (Santa Margherita di Pula)
libro: NPCF IV - ()

11573/492727 - 2010 - Identification of a new Chemical Class of Potent Antimycobacterial Compounds
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Alfonso, Salvatore; Battilocchio, Claudio; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: XX Meeting on Medicinal Chemistry (Abano Terme (PD))

11573/364093 - 2010 - Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Alfonso, Salvatore; A., De Logu; Nadia, Serra; Fabrizio, Manetti; Maurizio, Botta - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 8076-8084 - issn: 0968-0896 - wos: WOS:000283649900045 (44) - scopus: 2-s2.0-78449242124 (50)

11573/492716 - 2010 - Developing New Antiinflammatory and Analgesic Agents: Design, Synthesis, Biological and harmacological Evaluation
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Alfonso, Salvatore; Botta, M.; Manetti, F.; Sautebin, L; Ghelardini, C; Makovec, F; Giordani, A; Patrignani, P; Anzini, M. - 04a Atto di comunicazione a congresso
congresso: III European Workshop in Drug Synthesis (Siena)

11573/362423 - 2010 - Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-inflammatory and Analgesic Agents. Synthesis, in vitro and in vivo Biological Evaluation
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; Manetti, F; Botta, M; Sautebin, L; Rossi, A; Pergola, C; Ghelardini, C; Norcini, M; Makovec, F; Anzellotti, P; Cirilli, R; Ferretti, R; Patrignani, P; Anzini, M. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 723-733 - issn: 0022-2623 - wos: WOS:000273672100019 (45) - scopus: 2-s2.0-77249138784 (49)

11573/361148 - 2010 - New heterocyclic compounds with potential activity against parasitic protozoan: Trypanosoma and Leishmania
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Battilocchio, Claudio; V., Yardley; Alfonso, Salvatore - 04a Atto di comunicazione a congresso
congresso: COST Action Meeting CM0801 (Certosa di Pontignano, Siena, Italia)
libro: CM0801-New Drugs For Neglected Diseases - ()

11573/341214 - 2010 - One-pot conversions of olefins to cyclic carbonates and secondary allylic and homoallylic amines to cyclic carbamates
Stephen G., Davies; Ai M., Fletcher; Wataru, Kurosawa; James A., Lee; Poce, Giovanna; Paul M., Roberts; James E., Thomson; David M., Williamson - 01a Articolo in rivista
rivista: JOURNAL OF ORGANIC CHEMISTRY ([Washington, D.C: American Chemical Society) pp. 7745-7756 - issn: 0022-3263 - wos: WOS:000284080300027 (39) - scopus: 2-s2.0-78449236740 (41)

11573/341213 - 2010 - Doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure N-enoyl oxazolidin-2-ones: a mechanistic probe
Stephen G., Davies; M. A., Fletcher; Gesine J., Hermann; Poce, Giovanna; Paul M., Roberts; Andrew D., Smith; Miles J., Sweet; James E., Thomson - 01a Articolo in rivista
rivista: TETRAHEDRON-ASYMMETRY (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB) pp. 1635-1648 - issn: 0957-4166 - wos: WOS:000281356000001 (27) - scopus: 2-s2.0-77956264668 (21)

11573/225700 - 2009 - New pyrrole derivatives of BM 212: a new class of antimycobacterial agents.Design, synthesis, biological evaluation and study of their mode of action.
Biava, Mariangela; Porretta, G. C.; Poce, G; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
libro: NUOVE PROSPETTIVE IN CHIMICA FARMACEUTICA - ()

11573/368481 - 2009 - Pyrrole derivatives of BM212 as novel antimycobacterial agents Design, synthesis, biological evaluation and study of their mode of action
Biava, Mariangela; Porretta, Giulio Cesare; Battilocchio, Claudio; Poce, G; Pompei, R; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
libro: XXVIII CONGRESSO NAZIONALE DELLA SOCIETÀ DI MICROBIOLOGIA GENERALE E BIOTECNOLOGIE MICROBICHE - ()

11573/359624 - 2009 - 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; De Logu, A; Saddi, M; Meleddu, R; Manetti, F; De Rossi, E; Botta, M. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 4734-4738 - issn: 0223-5234 - wos: WOS:000271225800057 (72) - scopus: 2-s2.0-70349765643 (77)

11573/224933 - 2009 - Derivatives of BM 212: synthesis and biological evaluation of new derivatives with improved antimycobacterial activity.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Pompei, R; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: 10th Drug Development Seminar in conjunction with the COST Action CM0801 (Rauischholzhausen Castle, Germany)
libro: 10th Drug Development Seminar in conjunction with the COST Action CM0801 - ()

11573/172394 - 2009 - Potent in vitro and in vivo novel 1,5-Diarylpyrrole-3-acetic Esters COX-2 inhibitors.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Sautebin, L; Patrignani, P; Ghelardini, C; Giordani, A; Anzini, M. - 04a Atto di comunicazione a congresso
congresso: XXIII CONGRESSO NAZIONALE DELLA SOCIETÀ CHIMICA ITALIANA (Sorrento)
libro: XXIII CONGRESSO NAZIONALE DELLA SOCIETÀ CHIMICA ITALIANA - ()

11573/428134 - 2009 - C-9 Alkenylidine bridged macrolides: WO2008061189.
Poce, Giovanna; Porretta, Giulio Cesare; Biava, Mariangela - 01a Articolo in rivista
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 901-906 - issn: 1354-3776 - wos: WOS:000267103900010 (2) - scopus: 2-s2.0-67649383643 (2)

11573/55507 - 2009 - New pyrrole derivatives of BM 212: lead compound optimization strategy, Tuberculosis drug development. Targets, technologies and trials
Poce, Giovanna; Porretta, Giulio Cesare; Borzi, F; De Logu, A; De Rossi, E; Manetti, F; Botta, M; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: Gordon Conference (Magdalen College, Oxford)
libro: -- - ()

11573/52493 - 2009 - BM212 and its derivatives: lead optimization of a new class of antimycobacterial agents.
Poce, Giovanna; Porretta, Giulio Cesare; De Logu, A; De Rossi, E; Manetti, F; Botta, M; Biava, Mariangela - 04a Atto di comunicazione a congresso
congresso: 10th Drug Development Seminar in conjunction with the COST Action CM0801 (Rauischholzhausen Castle, Germania)
libro: none - ()

11573/228858 - 2008 - HPLC Enantioseparation and Absolute Configuration of Novel Antiinflammatory Pyrrole Derivatives
Biava, Mariangela; Cirilli, R; Fares, V; Ferretti, R; Gallinella, B; Poce, Giovanna; Porretta, Giulio Cesare; Supino, Sibilla; Villani, Claudio - 01a Articolo in rivista
rivista: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 775-780 - issn: 0899-0042 - wos: WOS:000256777400003 (12) - scopus: 2-s2.0-45849083178 (13)

11573/368120 - 2008 - Design and Synthesis of novel diarylpyrroles as p38 MAP kinase inhibitors
Biava, Mariangela; Porretta, G. C.; Poce, Giovanna; Giordani, A; Menziani, C. - 04a Atto di comunicazione a congresso
libro: XIX NATIONAL MEETING ON MEDICINAL CHEMISTRY DIVISION OF ITALIAN CHEMICAL SOCIETY (SCI) - ()

11573/367352 - 2008 - Design and synthesis of 1,5-diaryl-2-ethyl pyrrole derivatives and their evaluation as antimycobacterial agents
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; De Logu, A; Maleddu, R; De Rossi, E; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
libro: XIX NATIONAL MEETING ON MEDICINAL CHEMISTRY DIVISION OF ITALIAN CHEMICAL SOCIETY (SCI) - ()

11573/362033 - 2008 - 1,5-Diphenyl Pyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; De Logu, A; Saddi, M; Meleddu, R; Manetti, F; De Rossi, E; Botta, M. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3644-3648 - issn: 0022-2623 - wos: WOS:000256922800031 (83) - scopus: 2-s2.0-45749084929 (86)

11573/55497 - 2008 - New derivatives of BM 212 with improved antimycobacterial activity.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Pompei, R; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
libro: 2nd World Conference on Magic Bullets - ()

11573/228277 - 2008 - Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Sibilla, Supino; Fabrizio, Manetti; Stefano, Forli; Maurizio, Botta; Lidia, Sautebin; Antonietta, Rossi; Carlo, Pergola; Carla, Ghelardini; Monica, Norcini; Francesco, Makovec; Paola, Anzellotti; Roberto, Cirilli; Rosella, Ferretti; Bruno, Gallinella; F., La Torre; Maurizio, Anzini; Paola, Patrignani - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 8072-8081 - issn: 0968-0896 - wos: WOS:000258827800024 (20) - scopus: 2-s2.0-50349084855 (21)

11573/364227 - 2008 - New oxazolidinone derivatives as antibacterial agents with improved activity
Poce, Giovanna; Giovanni, Zappia; Porretta, Giulio Cesare; Botta, Bruno; Biava, Mariangela - 01a Articolo in rivista
rivista: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 97-121 - issn: 1354-3776 - wos: WOS:000253670500001 (28) - scopus: 2-s2.0-40749136990 (32)

11573/366568 - 2008 - BM212 and new derivatives as a new class of antimycobacterial agents.
Poce, Giovanna; Porretta, G. C.; Borzi, F; De Logu, A; De Rossi, E; Manetti, F; Botta, M; Biava, M. - 04a Atto di comunicazione a congresso
libro: First IRBM workshop on Medicinal & Organic Chemistry. - ()

11573/368289 - 2007 - New 1,5-diphenyl Pyrrole Derived from BM 212: a New class of Antimycobacterial Agents.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; De Logu, A; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: TUBERCULOSIS DRUG DEVELOPMENT. GORDON RESEARCH CONFERENCE (OXFORD)

11573/55496 - 2007 - New 1,5-diarylpyrrole with improved antimycobacterial activity
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; De Logu, A; Saddi, M; Botta, M. - 04a Atto di comunicazione a congresso
libro: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana - ()

11573/492438 - 2007 - Design, synthesis and screening of new antitubercular agents derived from BM 212
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Deidda, D.; Pompei, R.; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
congresso: VI Laboratorio di Metodologie Sintetiche in Chimica Farmaceutica (Siena)
libro: VI LABORATORIO DI METODOLOGIE SINTETICHE IN CHIMICA FARMACEUTICA - ()

11573/121312 - 2007 - New pyrroles with potential antimycobacterial, antifungal and COX-2 selective inhibiting activities. Synthetic methodologies
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Supino, S; Sleiter, G. - 01a Articolo in rivista
rivista: CURRENT ORGANIC CHEMISTRY (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 1092-1112 - issn: 1385-2728 - wos: WOS:000249103400005 (13) - scopus: 2-s2.0-34548247237 (14)

11573/364538 - 2007 - Cyclooxygenase-2 Inhibitors. 1,5-Diarylpyrrol-3-acetic Esters with Enhanced Inhibitory Activity toward Cyclooxygenase-2 and Improved Cyclooxygenase-2/Cyclooxygenase-1 Selectivity
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Supino, Sibilla; Cappelli, A; Vomero, S; Manetti, F; Botta, M; Sautebin, L; Rossi, A; Ghelardini, C; Vivoli, E; Makovec, F; Anzellotti, P; Patrignani, P; Anzini, M. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5403-5411 - issn: 0022-2623 - wos: WOS:000250557100018 (53) - scopus: 2-s2.0-35948946191 (58)

11573/364230 - 2006 - Antimycobacterial agents. Novel diarylpirrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Supino, S; Deidda, D; Pompei, R; Molicotti, P; Manetti, F; Botta, M. - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4946-4952 - issn: 0022-2623 - wos: WOS:000239459800018 (116) - scopus: 2-s2.0-33746924405 (126)

11573/52491 - 2006 - New 1,5-diphenyl pyrrole derived from BM 212: a new class of antimycobacterial Agents
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Supino, S; Pompei, R; Manetti, F; Botta, M. - 04a Atto di comunicazione a congresso
libro: “Tuberculosis 2006" - ()

11573/492426 - 2006 - Synthesis of new pyrrole derivatives of BM 212, a potent antimycobacterial compound
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Supino, Sibilla; Deidda, D.; Pompei, R.; Manetti, F.; Botta, M. - 04a Atto di comunicazione a congresso
congresso: XXII Convegno Nazionale della Divisione di Chimica Farmaceutica della SCI (Firenze)
libro: Atti del XXII Convegno Nazionale della Divisione di Chimica Farmaceutica della SCI - ()

11573/242012 - 2005 - ENANTIOMERS OF NOVEL ANTIINFLAMMATORY PYRROLE DERIVATIVES:ANALYTICAL AND SEMIPREPARATIVE HPLC SEPARATION AND CHIROPTICAL PROPERTIES.
Biava, Mariangela; Cirilli, R.; Ferretti, R.; Poce, Giovanna; Porretta, Giulio Cesare; Villani, C. . - 04a Atto di comunicazione a congresso
libro: 17th International Symposium on Chiral Discrimination - ()

11573/365959 - 2005 - Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Delia, Deidda; Raffaello, Pompei; Andrea, Tafi; Fabrizio, Manetti - 01a Articolo in rivista
rivista: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 1221-1230 - issn: 0968-0896 - wos: WOS:000226967900030 (57) - scopus: 2-s2.0-12844266203 (62)

11573/368576 - 2005 - 1,5-DIARYLPYRROLE DERIVATIVESAS NOVEL CLASSES OF ACTIVE AND SELECTIVE COX-2 INHIBITORS.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Tibuzzi, D; Cappelli, A; Vomero, S; Botta, M; Manetti, F; Sautebin, L; Rossi, A; Makovec, F; Anzini, A. - 04a Atto di comunicazione a congresso
libro: XVIII NATIONAL MEETING OF MEDICINAL CHEMISTRY DIVISION OF ITALIAN CHEMICAL SOCIETY (SCI) - ()

11573/368160 - 2004 - Nuovi derivati 1,5-difenilpirrolici derivati del BM212 attivi come agenti antitubercolari
Biava, M; Porretta, G. C.; Poce, Giovanna; Deidda, D; Pompei, R; Tafi, A; Manetti, F. - 04a Atto di comunicazione a congresso
libro: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica - ()

11573/368453 - 2004 - 1,5-diarylpyrrole-3-acetic acids and esters as novel class of potent and selective COX-2 inhibitors.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Cappelli, A.; Vomero, S.; Botta, M.; Manetti, F.; Giorni, G.; Sautebin, L.; Rossi, A.; Makovec, F.; Anzini, M. . - 04a Atto di comunicazione a congresso
libro: Twelfth FECHEM Conference on Heterocycles in Bio-organic Chemistry - ()

11573/327339 - 2004 - 1,5-DIARYLPYRROLE-3-ACETIC ACIDS AND ESTERS AS NOVEL CLASSES OF POTENT AND SELECTIVE COX-2 INHIBITORS.
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Cappelli, A; Vomero, S; Botta, M; Manetti, F; Giorni, G; Sautebin, L; Rossi, A; Makovec, F; Anzini, M. - 04a Atto di comunicazione a congresso
libro: CONFERENZA SULLA RICERCA SCIENTIFICA. FACOLTÀ DI FARMACIA . “DALLE MOLECOLE AGLI ORGANISMI” - ()

11573/52488 - 2004 - Pyrrole Derivatives as New Antimycobacterial Class: Synthesis, S.A.R., Molecular Modelling Considerations and Microbiological Activity
Biava, Mariangela; Porretta, Giulio Cesare; Poce, Giovanna; Pompei, R; Deidda, D; Tafi, A.; Manetti, F.; Botta, M. - 04a Atto di comunicazione a congresso
libro: Conferenza sulla Ricerca Scientifica, Facoltà di Farmacia, dalle Molecole agli Organismi - ()

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma