GIAMPIERO BARDELLA

Dottore di ricerca

ciclo: XXXIII


supervisore: Prof. Stefano Ferraina

Titolo della tesi: Topology of local information dynamics during motor decision in the premotor cortex of primates.

Despite recent works have investigated functional and effective cortical networks in animal models, the dynamical information transfer underneath most of the higher brain functions is still unknown. Here we address the issue by analysing at the mesoscopic scale neuronal activities from a multielectrode array (96 channels) in the dorsal premotor cortex (PMd) of rhesus monkeys during a countermanding reaching task, requiring dynamical decisions after visual instructions. We used transfer entropy and graph theory to extract the PMd effective network and to quantify the local information patterns corresponding to motor decision-making. We found that the network of information processing is highly heterogeneous, information-spreader hubs exist and exhibit topological differences between movement generation and inhibition. Interestingly, within our framework we identified the presence of a hierarchical organization between four neuronal activity classes involved in the decision-making process. Moreover, we observed that the hierarchical organization changed when movement was executed or cancelled after programmed. We propose that motor decisions are based on the reorganization of local network formed by few subclasses of neuronal modules hierarchically organized

Produzione scientifica

11573/1711968 - 2024 - Neural activity in quarks language. Lattice field theory for a network of real neurons
Bardella, Giampiero; Franchini, Simone; Pan, Liming; Balzan, Riccardo; Ramawat, Surabhi; Brunamonti, Emiliano; Pani, Pierpaolo; Ferraina, Stefano - 01a Articolo in rivista
rivista: ENTROPY (Basel : MDPI, 1999-) pp. 1-58 - issn: 1099-4300 - wos: (0) - scopus: (0)

11573/1684222 - 2024 - Response inhibition in Premotor cortex corresponds to a complex reshuffle of the mesoscopic information network
Bardella, Giampiero; Giuffrida, Valentina; Giarrocco, Franco; Brunamonti, Emiliano; Pani, Pierpaolo; Ferraina, Stefano - 01a Articolo in rivista
rivista: NETWORK NEUROSCIENCE (Network Neuroscience) pp. - - issn: 2472-1751 - wos: (0) - scopus: (0)

11573/1727438 - 2024 - Force monitoring reveals single trial dynamics of motor control in a stop signal task
Ramawat, Surabhi; Marc, Isabel B.; Di Bello, Fabio; Bardella, Giampiero; Ferraina, Stefano; Pani, Pierpaolo; Brunamonti, Emiliano - 01a Articolo in rivista
rivista: PHYSIOLOGICAL REPORTS () pp. - - issn: 2051-817X - wos: (0) - scopus: 2-s2.0-85210010501 (0)

11573/1679366 - 2023 - Reward prospect affects strategic adjustments in stop signal task
Giuffrida, V.; Marc, I. B.; Ramawat, S.; Fontana, R.; Fiori, L.; Bardella, G.; Fagioli, S.; Ferraina, S.; Brunamonti, E.; Pani, P. - 01a Articolo in rivista
rivista: FRONTIERS IN PSYCHOLOGY (Lausanne: Frontiers Editorial) pp. 1125066- - issn: 1664-1078 - wos: WOS:000961217800001 (2) - scopus: 2-s2.0-85152585440 (2)

11573/1682600 - 2023 - Functional network complexity reflects diverse reward contexts in macaque premotor cortex
Giuffrida, Valentina; Bardella, Giampiero; Ramawat, Surabhi; Marc, Isabel Beatrice; Fontana, Roberto; Brunamonti, Emiliano; Pani, Pierpaolo; Ferraina, Stefano - 04f Poster
congresso: Human Brain Project - Summit 2023 (Marisiglia - Francia)
libro: Human Brain Project - Summit 2023 - ()

11573/1692658 - 2023 - Neuronal population dynamics and network organizations reflect motivational context in monkey premotor cortex during movement execution and inhibition
Giuffrida, Valentina; Marc, Isabel Beatrice; Bardella, Giampiero; Ramawat, Surabhi; Fontana, Roberto; Brunamonti, Emiliano; Pani, Pierpaolo; Ferraina, Stefano - 04f Poster
congresso: NEUROSCIENCE ANNUAL MEETING 2023 (Washington, DC)
libro: Neuroscience 2023 abstracts - ()

11573/1692645 - 2023 - Local field potentials in macaque dorsal premotor cortex are modulated by the manipulation of acquired ordinal information in a transitive inference task
Marc, I. B.; Giuffrida, V.; Ramawat, S.; Andujar, M.; Bardella, G.; Pani, P.; Ferraina, S.; Brunamonti, E. - 04f Poster
congresso: NEUROSCIENCE ANNUAL MEETING 2023 (Washington, DC)
libro: Neuroscience 2023 abstracts - ()

11573/1692647 - 2023 - Motor decision is influenced by the difficulty of solving a numerical comparison in a selective stop signal task
Marc, I.; Segreti, M.; Giuffrida, V.; Ramawat, S.; Paul, Ann; Bardella, G.; Pani, P.; Ferraina, S.; Brunamonti, E. - 04f Poster
congresso: NEUROSCIENCE ANNUAL MEETING 2023 (Washington, DC)
libro: Neuroscience 2023 abstracts - ()

11573/1682738 - 2023 - The premises of a transitive inference task modulate the synchrony of local field potentials in macaque dorsal premoto rcortex
Marc, Isabel Beatrice; Bardella, Giampiero; Giuffrida, Valentina; Ramawat, Surabhi; Pani, Pierpaolo; Ferraina, Stefano; Brunamonti, Emiliano - 04f Poster
congresso: 13th Primate Neurobiology Meeting 2023 (Goettingen; Germany)
libro: The premises of a transitive inference task modulate the synchrony of local field potentials in macaque dorsal premotor cortex - ()

11573/1669953 - 2023 - Restart errors reaction time of a two-step inhibition process account for the violation of the race model’s independence in multi-effector selective stop signal task
Marc, Isabel Beatrice; Giuffrida, Valentina; Ramawat, Surabhi; Fiori, Lorenzo; Fontana, Roberto; Bardella, Giampiero; Fagioli, Sabrina; Ferraina, Stefano; Pani, Pierpaolo; Brunamonti, Emiliano - 01a Articolo in rivista
rivista: FRONTIERS IN HUMAN NEUROSCIENCE (Lausanne : Frontiers Research Foundation) pp. - - issn: 1662-5161 - wos: WOS:000937342100001 (2) - scopus: 2-s2.0-85148654336 (2)

11573/1681947 - 2023 - The transitive inference task to study the neuronal correlates of memory-driven decision making: a monkey neurophysiology perspective
Ramawat, Surabhi; Marc, Isabel Beatrice; Ceccarelli, Francesco; Ferrucci, Lorenzo; Bardella, Giampiero; Ferraina, Stefano; Pani, Pierpaolo; Brunamonti, Emiliano - 01a Articolo in rivista
rivista: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 105258- - issn: 0149-7634 - wos: WOS:001019059200001 (2) - scopus: 2-s2.0-85161351209 (2)

11573/1646091 - 2022 - Reply to: Hannah et al. (2021) Commentary: ‘Does action-stopping involve separate pause and cancel processes? A view from premotor cortex’: Action-stopping models must consider the role of the dorsal premotor cortex
Pani, P.; Giarrocco, F.; Bardella, G.; Brunamonti, E.; Ferraina, S. - 01b Commento, Erratum, Replica e simili
rivista: CORTEX (Primo editore: Tipografica Varese, Varese Attuale:Masson SPA:via Flli Bressan 2, I 20126 Milan Italy:011 39 02 27074286, EMAIL: aboonamenti@masson.it, INTERNET: http://www.masson.it, Fax: 011 39 02 27074210) pp. 160-163 - issn: 0010-9452 - wos: WOS:000812347500002 (0) - scopus: 2-s2.0-85129323328 (0)

11573/1621694 - 2022 - Different Contribution of the Monkey Prefrontal and Premotor Dorsal Cortex in Decision Making During a Transitive Inference Task
Ramawat, S.; Mione, V.; Di Bello, F.; Bardella, G.; Genovesio, A.; Pani, P.; Ferraina, S.; Brunamonti, E. - 01a Articolo in rivista
rivista: NEUROSCIENCE (Oxford: Elsevier Ltd. Oxford; New York: Pergamon Press) pp. 147-162 - issn: 0306-4522 - wos: WOS:000781963000003 (7) - scopus: 2-s2.0-85124416412 (8)

11573/1470694 - 2021 - Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex
Giarrocco, F.; Bardella, G.; Giamundo, M.; Fabbrini, F.; Brunamonti, E.; Pani, P.; Ferraina, S. - 01a Articolo in rivista
rivista: CORTEX (Primo editore: Tipografica Varese, Varese Attuale:Masson SPA:via Flli Bressan 2, I 20126 Milan Italy:011 39 02 27074286, EMAIL: aboonamenti@masson.it, INTERNET: http://www.masson.it, Fax: 011 39 02 27074210) pp. 326-340 - issn: 0010-9452 - wos: WOS:000615719500024 (16) - scopus: 2-s2.0-85097745091 (19)

11573/1336004 - 2020 - The small scale functional topology of movement control: Hierarchical organization of local activity anticipates movement generation in the premotor cortex of primates
Bardella, Giampiero; Pani, Pierpaolo; Brunamonti, Emiliano; Giarrocco, Franco; Ferraina, Stefano - 01a Articolo in rivista
rivista: NEUROIMAGE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. - - issn: 1053-8119 - wos: WOS:000509662600054 (7) - scopus: 2-s2.0-85076508346 (6)

11573/1190409 - 2016 - Hierarchical organization of functional connectivity in the mouse brain: a complex network approach
Bardella, Giampiero; Bifone, Angelo; Gabrielli, Andrea; Gozzi, Alessandro; Squartini, Tiziano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 32060- - issn: 2045-2322 - wos: WOS:000381606700001 (22) - scopus: 2-s2.0-84983335529 (26)

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