FRANCESCO GIOSUÈ IRACE

Dottore di ricerca

ciclo: XXXIV

Titolo della tesi: OXIDATIVE STRESS AND AUTOPHAGY IN THORACIC AORTIC ANEURYSMS

Thoracic aortic aneurysms (TAA) pathogenesis and progression include many mechanisms. In this study, we investigated the role of autophagy, oxidative stress, and endothelial dysfunction in 36 TAA patients and 23 control patients. Univariable and multivariable analyses were performed. TAA patients displayed higher oxidative stress and endothelial dysfunction then control patients. Autophagy in the TAA group was reduced. The association of oxidative stress and autophagy with aortic disease supports the role of these processes in TAA. We demonstrate a putative role of Nox2 and autophagy dysregulation in human TAA. These findings could pinpoint novel treatment targets to prevent or limit TAA progression.

Produzione scientifica

11573/1704209 - 2024 - Extended septal myectomy for obstructive hypertrophic cardiomyopathy and its impact on mitral valve function

Lio, Antonio; D’Ovidio, Mariangela; Chirichilli, Ilaria; Saitto, Guglielmo; Nicolò, Francesca; Russo, Marco; Irace, Francesco; Ranocchi, Federico; Davoli, Marina; Musumeci, Francesco - 01a Articolo in rivista

rivista: JOURNAL OF CARDIOVASCULAR MEDICINE (Lippincott Williams & Wilkins) pp. 210-217 - issn: 1558-2027 - wos: WOS:001158283700003 (0) - scopus: 2-s2.0-85184290788 (0)

11573/1704210 - 2024 - Systematic adjustment of root dimensions to cusp size in aortic valve repair: a computer simulation

Marom, Gil; Weltert, Luca Paolo; Raanani, Ehud; Chirirchilli, Ilaria; Giebels, Christian; Irace, Francesco Giosue; De Paulis, Ruggero; Schäfers, Hans-Joachim - 01a Articolo in rivista

rivista: INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY (Oxford: Oxford University Press) pp. - - issn: 2753-670X - wos: (0) - scopus: (0)

11573/1698186 - 2023 - Panoramic on Epigenetics in Coronary Artery Disease and the Approach of Personalized Medicine

Bergonzini, Marcello; Loreni, Francesco; Lio, Antonio; Russo, Marco; Saitto, Guglielmo; Cammardella, Antonio; Irace, Francesco; Tramontin, Corrado; Chello, Massimo; Lusini, Mario; Nenna, Antonio; Ferrisi, Chiara; Ranocchi, Federico; Musumeci, Francesco - 01a Articolo in rivista

rivista: BIOMEDICINES (Basel : MDPI) pp. - - issn: 2227-9059 - wos: WOS:001094150700001 (0) - scopus: 2-s2.0-85175470261 (1)

11573/1698185 - 2023 - Aortic Annuloplasty: Focus on the Use of an External Teflon Ring

Chirichilli, Iilaria; Ricci, Alessandro; Weltert, Luca; Torre, Mario; Irace, Francesco; Scaffa, Raffaele; Folino, Giulio; Salica, Andrea; D'aleo, Salvatore; Wolf, Lorenzo Guerrieri; Fusca, Samuel; Bellisario, Alessandro; Marra, Giulia; Andreis, Marco; Ciani, Camilla; Forcina, Sara; De Paulis, Ruggero - 01a Articolo in rivista

rivista: SURGICAL TECHNOLOGY INTERNATIONAL ([Oklahoma City] : Century Press, c1991-) pp. - - issn: 1090-3941 - wos: (0) - scopus: (0)

11573/1687788 - 2023 - Reply: Leave well enough alone

Irace, Francesco Giosuè; Chirichilli, Ilaria; De Paulis, Ruggero - 01a Articolo in rivista

rivista: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (New York: Elsevier Orlando, FL: Mosby Year Book) pp. - - issn: 0022-5223 - wos: WOS:001103026000001 (0) - scopus: 2-s2.0-85173479593 (0)

11573/1698187 - 2023 - Aortic Valve Replacement: Understanding Predictors for the Optimal Ministernotomy Approach

Irace, Francesco Giosuè; Chirichilli, Ilaria; Russo, Marco; Ranocchi, Federico; Bergonzini, Marcello; Lio, Antonio; Nicolò, Francesca; Musumeci, Francesco - 01a Articolo in rivista

rivista: JOURNAL OF CLINICAL MEDICINE (MDPI Publishing, Basel, Switzerland) pp. - - issn: 2077-0383 - wos: WOS:001103316400001 (0) - scopus: 2-s2.0-85176576839 (1)

11573/1692413 - 2023 - Temporary intravascular shunts and limb salvage in civilian vascular trauma

Martinelli, Ombretta; Miceli, Francesca; Cuozzo, Simone; Irace, Francesco Giosuè; Avenia, Stefano; Iannone, Immacolata; Clementi, Ilaria; Sapienza, Paolo; Bellini, Maria Irene - 01a Articolo in rivista

rivista: FRONTIERS IN SURGERY (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-875X - wos: WOS:001119819300001 (0) - scopus: (0)

11573/1664303 - 2022 - Twenty-year experience of aortic valve reimplantation using the Valsalva graft

Chirichilli, Ilaria; Scaffa, Raffaele; Irace, Francesco Giosuè; Salica, Andrea; Weltert, Luca Paolo; D'aleo, Salvatore; Chiariello, Luigi; De Paulis, Ruggero - 01a Articolo in rivista

rivista: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (Oxford: Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery Amsterdam: Elsevier Science Berlin: Springer, 1987-) pp. - - issn: 1010-7940 - wos: WOS:000943585200001 (2) - scopus: 2-s2.0-85149999029 (1)

11573/1616782 - 2022 - The black root: Aortic valve sparing in alkaptonuria

Folino, G.; Scaffa, R.; Salica, A.; Weltert, L.; D'aleo, S.; Guerrieri, L.; Irace, F.; Coscioni, E.; Gerosa, G.; De Paulis, R. - 01a Articolo in rivista

rivista: JOURNAL OF CARDIAC SURGERY (Mount Kisco, N.Y. : Futura Pub. Co., c1986-) pp. - - issn: 0886-0440 - wos: WOS:000754389800001 (1) - scopus: 2-s2.0-85124510055 (1)

11573/1663397 - 2022 - Mitral repair of myxomatous valves with simple annuloplasty: a follow-up up to 12 years

Folino, Giulio; Salica, Andrea; Scaffa, Raffaele; Irace, Francesco Giosuè; Weltert, Luca Paolo; Bellisario, Alessandro; Gerosa, Gino; De Paulis, Ruggero - 01a Articolo in rivista

11573/1655284 - 2022 - Reimplantation versus aortic ring annuloplasty in bicuspid valve with borderline aortic root ectasia

Irace, F. G.; Chirichilli, I.; Folino, G.; Salica, A.; Guerrieri Wolf, L.; Scaffa, R.; D'aleo, S.; Weltert, L. P.; De Paulis, R. - 01a Articolo in rivista

rivista: JTCVS TECHNIQUES (New York: Elsevier Inc) pp. - - issn: 2666-2507 - wos: WOS:000873983200007 (0) - scopus: 2-s2.0-85135956230 (0)

11573/1655282 - 2021 - Root Reimplantation and Aortic Annuloplasty With External Ring in Bicuspid Aortic Valve: An Anatomical Comparison

Chirichilli, Ilaria; Irace, Francesco Giosue'; Salica, Andrea; D'aleo, Salvatore; Guerrieri Wolf, Lorenzo; Garufi, Luigi; De Paulis, Ruggero - 01a Articolo in rivista

rivista: SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY (W B Saunders Company:Fulfillment Department, The Curtis Center, Independence Square West:Philadelphia, PA 19106:(800)654-2452, (215)238-7800, EMAIL: wbspcs@harcourt.com, INTERNET: http://elsevierhealth.com, Fax: (215)238-6445) pp. 844-851 - issn: 1043-0679 - wos: (0) - scopus: 2-s2.0-85111551659 (2)

11573/1616819 - 2021 - Aortic root anatomy after aortic valve reimplantation

Irace, F. G.; Chirichilli, I.; Salica, A.; D'aleo, S.; Guerrieri Wolf, L.; Garufi, L.; De Paulis, R. - 01a Articolo in rivista

rivista: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (New York: Elsevier Orlando, FL: Mosby Year Book) pp. - - issn: 0022-5223 - wos: WOS:000955238200001 (6) - scopus: 2-s2.0-85105345030 (7)

11573/1571385 - 2021 - Role of oxidative stress and autophagy in thoracic aortic aneurysms

Irace, Francesco G.; Cammisotto, Vittoria; Valenti, Valentina; Maurizio, Forte; Schirone, Leonardo; Bartimoccia, Simona; Alessandra, Iaccarino; Peruzzi, Mariangela; Schiavon, Sonia; Morelli, Andrea; Marullo, Antonino G. M.; Miraldi, Fabio; Nocella, Cristina; Ruggero De Paulis, ; Umberto, Benedetto; Greco, Ernesto; Biondi Zoccai, Giuseppe; Sciarretta, Sebastiano; Carnevale, Roberto; Frati, Giacomo - 01a Articolo in rivista

rivista: JACC. BASIC TO TRANSLATIONAL SCIENCE (New York: Elsevier B.V.) pp. 719-730 - issn: 2452-302X - wos: WOS:000711000100001 (12) - scopus: 2-s2.0-85122627701 (12)

11573/1546918 - 2021 - Optimized use of the "skirt" of the Valsalva graft for the completion Bentall

Scaffa, Raffaele; Salica, Andrea; Weltert, Luca; Irace, Francesco Giosuè; Wolf, Lorenzo Guerrieri; D'aleo, Salvo; Bellisario, Alessandro; De Paulis, Ruggero - 01a Articolo in rivista

rivista: ANNALS OF THORACIC SURGERY ([Boston etc.]: [Little Brown & Co. etc.]) pp. - - issn: 0003-4975 - wos: WOS:000697696500014 (3) - scopus: 2-s2.0-85115034376 (3)

11573/1667787 - 2020 - Semeiotica dell'apparato Cardiovascolare

Amoroso, Antonio; Basili, Stefania; Biffoni, Marco; Catania, Antonio; Casella, Giovanni; Caronna, Roberto; Chirletti, Piero; D'orazio, Valerio; Gentile, Vincenzo; Irace, Luigi; Mascagni, Domenico; Mezzetti, Giuseppe; Mongardini, Massimo; Monti, Massimo; Angelo Rendina, Erano; Urcioli Collaboratori Capitolo 5: Alessia Alunno, Paolo; Belli, Cristina; Benhamida, Jamila; Castiglione, Anna; Di Girolamo, Alessia; Dorelli, Barbara; Faccenna, Federico; Gattuso, Roberto; Gigante, Antonietta; Giosuè Irace, Francesco; Jabbout, Jihad; Malaj, Alban; Marino, Mario; Martinelli, Ombretta; Maruca, Debora; Proietti, Camilla - 03c Manuale Didattico

11573/1386538 - 2020 - Long-term follow-up of Bentall procedure using the Perimount bioprosthesis and the Valsalva graft

Chirichilli, Ilaria; Irace, Francesco Giosuè; D'aleo, Salvatore; Folino, Giulio; Weltert, Luca Paolo; Scaffa, Raffaele; Nardella, Saverio; De Paulis, Ruggero - 01a Articolo in rivista

rivista: INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY (-[S.l.] : European Association for Cardio-thoracic Surgery -Oxford : Elsevier Science) pp. - - issn: 1569-9285 - wos: WOS:000537398800004 (4) - scopus: 2-s2.0-85084101588 (3)

11573/1361388 - 2020 - A direct correlation between commissural orientation and annular shape in bicuspid aortic valves: a new anatomical and computed tomography classification

Chirichilli, Ilaria; Irace, Francesco Giosue'; Weltert, Luca Paolo; Salica, Andrea; Guerrieri Wolf, Lorenzo; Fusca, Samuel; Ricci, Alessandro; De Paulis, Ruggero - 01a Articolo in rivista

11573/1361374 - 2020 - Ascending aorta disruption after thoracic blunt trauma

Irace, F.; Rico, V.; Ciuffetta, D.; Miraldi, F. - 01i Case report

rivista: CHINESE JOURNAL OF TRAUMATOLOGY (Chongqing : Editorial Board of Chinese Journal of Traumatology) pp. 32-33 - issn: 1008-1275 - wos: WOS:000518215500008 (0) - scopus: 2-s2.0-85078257240 (0)

11573/1698188 - 2020 - Procedure cardiovascolari - Protesi valvolari cardiache

Miraldi, Fabio; Chourda, Emmanouela; Marullo, Antonino G. M.; Irace, Francesco Giosue - 02a Capitolo o Articolo

libro: Malattie cardiovascolari Approccio clinico e scientifico - (9788855320665)

11573/1386533 - 2020 - External stents for vein grafts in coronary artery bypass grafting: targeting intimal hyperplasia

Weltert, Luca Paolo; Wolf, Lorenzo Guerrieri; Garufi, Luigi; Scaffa, Raffaele; Salica, Andrea; Ricci, Alessandro; Irace, Francesco Giosuè; Fusca, Samuel; D'aleo, Salvatore; Chirichilli, Ilaria; Bellisario, Alessandro; De Paulis, Ruggero - 01a Articolo in rivista

rivista: SURGICAL TECHNOLOGY INTERNATIONAL ([Oklahoma City] : Century Press, c1991-) pp. 197-201 - issn: 1090-3941 - wos: WOS:000587503100028 (0) - scopus: 2-s2.0-85085630186 (2)

11573/1252879 - 2019 - Morphological modification of the aortic annulus in tricuspid and bicuspid valves after aortic valve reimplantation: an electrocardiography-gated computed tomography study

Chirichilli, Ilaria; Irace, Francesco; Weltert, Luca; Tsuda, Kazumasa; Scaffa, Raffaele; Salica, Andrea; Galea, Nicola; De Paulis, Ruggero - 01a Articolo in rivista

11573/1321744 - 2019 - Latest Advances in Annuloplasty Protheses for Valvular Reconstructive Surgery

Weltert, Luca; Licitra, Rosaria; Salica, Andrea; Irace, Francesco; De Paulis, Ruggero - 01a Articolo in rivista

rivista: SURGICAL TECHNOLOGY INTERNATIONAL ([Oklahoma City] : Century Press, c1991-) pp. - - issn: 1090-3941 - wos: WOS:000567363300002 (0) - scopus: 2-s2.0-85074744191 (2)

11573/1178862 - 2018 - One-year outcomes after ruptured abdominal aortic aneurysms repair: is endovascular aortic repair the best choice? A single-center experience

Martinelli, Ombretta; Fenelli, Cecilia; Ben-Hamida, Jamila Ben; Fresilli, Mauro; Irace, Francesco Giosuè; Picone, Veronica; Malaj, Alban; Gossetti, Bruno; Irace, Luigi - 01a Articolo in rivista

rivista: ANNALS OF VASCULAR SURGERY (Springer-Verlag New York Incorporated:175 Fifth Avenue:New York, NY 10010:(212)460-1500, EMAIL: orders@springer-ny.com, INTERNET: http://www.springer-ny.com, Fax: (212)533-3503) pp. 63-69 - issn: 0890-5096 - wos: WOS:000446674300005 (8) - scopus: 2-s2.0-85049298564 (8)

11573/1061014 - 2017 - Open and endovascular treatment by covered and multilayer stents in the therapy of renal artery aneurysms. Mid and long term outcomes in a single center experience

Irace, L.; Ben Hamida, Jamila; Martinelli, O.; Stumpo, R.; Irace, F. G.; Venosi, S.; Gattuso, R.; Berloco, P. B.; Gossetti, B. - 01a Articolo in rivista

rivista: IL GIORNALE DI CHIRURGIA (CIC Edizioni Internazionali:Corso Trieste N 42, I 00198 Rome Italy:011 39 06 8412673, EMAIL: abbonamenti@gruppocic.it, INTERNET: http://www.gruppocic.it, Fax: 011 39 06 8412688) pp. 219-224 - issn: 0391-9005 - wos: WOS:000426956100002 (8) - scopus: 2-s2.0-85039798775 (9)

11573/927666 - 2017 - Therapeutical options in the management of carotid dissection

Martinelli, Ombretta; Venosi, Salvatore; Ben Hamida, Jamila; Malaj, Alban; Belli, Cristina; Irace, Francesco Giosue'; Gattuso, Roberto; Frati, Giacomo; Gossetti, Bruno; Irace, Luigi - 01a Articolo in rivista

rivista: ANNALS OF VASCULAR SURGERY (Springer-Verlag New York Incorporated:175 Fifth Avenue:New York, NY 10010:(212)460-1500, EMAIL: orders@springer-ny.com, INTERNET: http://www.springer-ny.com, Fax: (212)533-3503) pp. 69-76 - issn: 0890-5096 - wos: WOS:000402642100024 (14) - scopus: 2-s2.0-85009192456 (18)

11573/924218 - 2016 - Optimizing the exposure in minimally invasive mitral surgery. a new left atrial retractor system

Greco, Ernesto; Rose, David; Irace, Francesco Giosue'; Frati, Giacomo - 01a Articolo in rivista

rivista: JOURNAL OF THORACIC DISEASE (Hong Kong : Pioneer Bioscience Publishing Company) pp. 3728-3732 - issn: 2072-1439 - wos: WOS:000391175400096 (5) - scopus: 2-s2.0-85010295341 (6)

11573/1089336 - 2015 - Video assistance in mitral surgery. reaching the thru port access

Irace, Francesco G; Rose, David; D'ascoli, Riccardo; Caldaroni, Federica; Andriani, Ines; Piscioneri, Fernando; Vitulli, Piergiusto; Piattoli, Matteo; Tritapepe, Luigi; Greco, Ernesto - 01a Articolo in rivista

rivista: JOURNAL OF VISUALIZED SURGERY (香港 : AME Publishing Company Xiānggǎng : AME Publishing Company) pp. - - issn: 2221-2965 - wos: (0) - scopus: (0)

11573/899078 - 2015 - Recent developments in minimally invasive cardiac surgery. evolution or revolution

Marullo, Antonino G. M; Irace, Francesco G.; Vitulli, Piergiusto; Peruzzi, Mariangela; Rose, David; D'ascoli, Riccardo; Iaccarino, Alessandra; Pisani, Angelo; De Carlo, Carlotta; Mazzesi, Giuseppe; Barretta, Antonio; Greco, Ernesto - 01a Articolo in rivista

rivista: BIOMED RESEARCH INTERNATIONAL ([London]: [Hindawi] Cairo: Hindawi Publishing Corporation) pp. - - issn: 2314-6133 - wos: WOS:000363135100001 (18) - scopus: 2-s2.0-84945548679 (26)

11573/558069 - 2013 - Extra-anatomical bypass: a surgical option for recurrent aortic coarctation.

Malaj, A; Martinelli, Ombretta; Irace, Fg; Jabbour, J; Gossetti, Bruno; Mazzesi, Giuseppe - 01a Articolo in rivista

rivista: CASE REPORTS IN VASCULAR MEDICINE (Cairo: Hindawi Publishing Corporation) pp. - - issn: 2090-6986 - wos: (0) - scopus: (0)

11573/444524 - 2012 - Mid- and long-term results of endovascular treatment in thoracic aorta blunt trauma

Irace, Luigi; Laurito, Antonella; Venosi, Salvatore; Irace, Francesco Giosue'; Alban, Malay; Gossetti, Bruno; Gattuso, Roberto; Martinelli, Ombretta - 01a Articolo in rivista

rivista: THE SCIENTIFIC WORLD JOURNAL (-NEW YORK, USA: -Newbury : TheScientificWorld. -Boynton Beach, Fla. : Scientific World.) pp. 1-4 - issn: 1537-744X - wos: WOS:000307064900001 (10) - scopus: 2-s2.0-84862329716 (12)

11573/408036 - 2009 - Trattamento chirurgico degli aneurismi dell'aorta addominale in urgenza: risultati del trattamento chirurgico classico e propettive dell'esclusione endovascolare.

Martinelli, Ombretta; Felli, Mmg; Alunno, A; Castiglione, A; Mansour, W; Irace, Fg; Malaj, A; De Marchi, F; Irace, Luigi - 01a Articolo in rivista

rivista: MINERVA CARDIOANGIOLOGICA (Edizioni Minerva Medica:Corso Bramante 83-85, 10126 Turin Italy:011 39 011 678282318, EMAIL: journals.dept@minervamedica.it, INTERNET: http://www.minervamedica.it, Fax: 011 39 011 674502) pp. - - issn: 0026-4725 - wos: (0) - scopus: (0)