FIAMMETTA VERNI'

Professore associato


email: fiammetta.verni@uniroma1.it




PERSONAL DATA
Name: Fiammetta VERNI'
Citizenship: Italian
Work address: Department of Biology and Biotechnology Charles Darwin
Sapienza University of Rome
Piazzale Aldo Moro, 5 - 00185 Rome, Italy
E-mail: fiammetta.verni@uniroma1.it
ACADEMIC TRAINING AND WORK POSITIONS
2022 to present Associate Professor of Genetics, Sapienza University of Rome (Department of
Biology and Biotechnology Charles Darwin )
1997 Researcher, Sapienza University of Rome (Department of Biology and Biotechnology
Charles Darwin )
1995 Annual research fellowship of Telethon, Sapienza, University of Rome
1994 Annual research fellowship of Istituto Pasteur Fondazione Cenci Bolognetti Sapienza,
University of Rome
1994 PhD Degree in Evolutionary Biology, Sapienza, University of Rome
1989 Research Fellowship at Cornell University (Ithaca N.Y.) USA
1988 Biological Sciences Degree, Sapienza University of Rome.
RESEARCH EXPERIENCE
In the past my research activity has mainly concerned the characterization of genes controlling
different aspects of Drosophila cell cycle. Currently, I focused my attention on the impact of the
diet on genome integrity. In particular I m studying the relationship between vitamin B6,
genome instability, diabetes and cancer using Drosophila as a model system, with the aim of
clarify the mechanisms behind this relationship.
TECHNICAL SKILLS AND COMPETENCES
General genetic and cytogenetic methodologies. Immunofluorescence. General molecular
biology methodologies.
PUBLICATIONS (of the last 10 years):
1. Pilesi E, Angioli C, Graziani C, Parroni A, Contestabile R, Tramonti A and Fiammetta Vernì. A
gene-nutrient interaction between vitamin B6 and serine hydroxymethyltransferase (SHMT)
affects genome integrity in Drosophila J Cell Physiol 2023 (in revision).
2. La Torre M, Merigliano C, Maccaroni K, Chojnowski A, Goh WI, Giubettini M, Vernì F, Capanni
C, Rhodes D, Wright G, Burke B, Soddu S, Burla R, Saggio I. Combined alteration of lamin and
nuclear morphology influences the localization of the tumor-associated factor AKTIP. J Exp Clin
Cancer Res. 2022 41:273. doi: 10.1186/s13046-022-02480-5.
3. Mascolo E, Liguori F, Merigliano C, Schiano L, Gnocchini E, Pilesi E, Volonté C, Di Salvo ML,
Contestabile R, Tramonti A, Vernì F. Vitamin B6 rescues insulin resistance and glucose-induced
DNA damage caused by reduced activity of Drosophila PI3K. J Cell Physiol 2022 237:3578-3586.
doi: 10.1002/jcp.30812.
4.Vernì F. DNA Damage Response (DDR) and DNA Repair. Int J Mol Sci. 2022 vol 23:7204. doi:
10.3390/ijms23137204
5.Gnocchini E, Pilesi E, Schiano L, Vernì F. Vitamin B6 deficiency promotes loss of heterozygosity
(LOH) at the Drosophila warts (wts) locus Int J Mol Sci 2022, vol 23: 6089 doi:
10.3390/ijms23116087.
6. Liguori F, Mascolo E, Vernì F. The genetics of diabetes: what we can learn from Drosophila.
Int J Mol Sci 2021, vol. 22, ISSN: 1661-6596, doi: 10.3390/ijms222011295
7. Merigliano C, et al , AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT
III subunits to the midbody. PLOS GENETICS (2021)., vol. 17, ISSN: 1553-7404, doi:
10.1371/journal.pgen.1009757
8. Mascolo E, Liguori F, Stufera Mecarelli L, Amoroso N, Merigliano C, Amadio S, Volonté C,
Contestabile R, Tramonti A, Vernì F. Functional Inactivation of Drosophila GCK Orthologs
Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2. Int J Mol Sci.
2021;22. doi:10.3390/ijms22020918
9. Burla R, La Torre M, Maccaroni K, Verni F, Giunta S, Saggio I. Interplay of the nuclear
envelope with chromatin in physiology and pathology. Nucleus. 2020;11: 205 218.
doi:10.1080/19491034.2020.1806661
10. Mascolo E, Vernì F. Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. Int J
Mol Sci. 2020;21. doi:10.3390/ijms21103669
11. Licursi V, Anzellotti S, Favaro J, Sineri S, Carucci N, Cundari E, Fiore M, Guarguaglini G,
Pippa S, Nisi P S, Vernì F, Biagioni S, Cacci E, Amendola R, Lupo G, Negri R. X-ray irradiated
cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation
with dose-dependent kinetics. Sci Rep. 2020;10: 6562. doi:10.1038/s41598-020-63348-2
12. Contestabile R, di Salvo ML, Bunik V, Tramonti A, Vernì F. The multifaceted role of vitamin
B(6) in cancer: Drosophila as a model system to investigate DNA damage. Open Biol.
2020;10:200034. doi:10.1098/rsob.200034
13. Raimondo D, Remoli C, Astrologo L, Burla R, La Torre M, Vernì F, Tagliafico E, Corsi A, Del
Giudice S, Persichetti A, Giannicola G, Robey PG, Riminucci M, Saggio. Changes in gene
expression in human skeletal stem cells transduced with constitutively active Gs correlates
with
hallmark histopathological changes seen in fibrous dysplastic bone. PLoS One. 2020;15:
e0227279. doi:10.1371/journal.pone.0227279
14. Mascolo E, Amoroso N, Saggio I, Merigliano C, Vernì F. Pyridoxine/pyridoxamine 5 -
phosphate oxidase (Sgll/PNPO) is important for DNA integrity and glucose homeostasis
maintenance in Drosophila. J Cell Physiol. 2020;235: 504 512. doi:10.1002/jcp.28990
15. Mascolo E, Barile A, Mecarelli LS, Amoroso N, Merigliano C, Massimi A, Saggio I, Hansen
T, Tramonti A, Di Salvo M., Barbetti F, Contestabile R, Vernì F. The expression of four pyridoxal
kinase (PDXK) human variants in Drosophila impacts on genome integrity. Sci Rep. 2019;9:
14188. doi:10.1038/s41598-019-50673-4
16. Merigliano C, Mascolo E, Cesta A, Saggio I, Vernì F. A new role for Drosophila Aurora-A in
maintaining chromosome integrity. Chromosoma. 2019;128: 41 52. doi:10.1007/s00412-018-
00687-0
17. Burla R, La Torre M, Zanetti G, Bastianelli A, Merigliano C, Del Giudice S, Vercelli A, Di
Cunto F, Boldo M, Vernì F, Saggio I. p53-Sensitive Epileptic Behavior and Inflammation in Ft1
Hypomorphic Mice. Front Genet. 2018;9: 581. doi:10.3389/fgene.2018.00581
18. Merigliano C, Mascolo E, Burla R, Saggio I, Vernì F. The Relationship Between Vitamin B6,
Diabetes and Cancer. Front Genet. 2018;9: 388. doi:10.3389/fgene.2018.00388
19.Merigliano C, Mascolo E, La Torre M, Saggio I, Vernì F. Protective role of vitamin B6 (PLP)
against DNA damage in Drosophila models of type 2 diabetes. Sci Rep. 2018;8: 11432.
doi:10.1038/s41598-018-29801-z
20. Burla R, La Torre M, Merigliano C, Vernì F, Saggio I. Genomic instability and DNA
replication defects in progeroid syndromes. Nucleus. 2018;9: 368 379.
doi:10.1080/19491034.2018.1476793
21. La Torre M, Merigliano C, Burla R, Mottini C, Zanetti G, Del Giudice S, Carcuro M, Virdia
I, Bucciarelli E, Manni I, Rampioni Vinciguerra G, Piaggio G, Riminucci M, Cumano A,
Bartolazzi A, Vernì F, Soddu S, Gatti M, Saggio I. Mice with reduced expression of the telomere
associated protein Ft1 develop p53-sensitive progeroid traits. Aging Cell. 2018;17: e12730.
doi:10.1111/acel.12730
22. Di Giorgio ML, Esposito A, Maccallini P, Micheli E, Bavasso F, Gallotta I, Vernì F, Feiguin
F, Cacchione S, McCabe BD, Di Schiavi E, Raffa GD. WDR79/TCAB1 plays a conserved role in the
control of locomotion and ameliorates phenotypic defects in SMA models. Neurobiol Dis.
2017;105: 42 50. doi:10.1016/j.nbd.2017.05.005
23. Bianchi FT, Tocco C, Pallavicini G, Liu Y, Vernì F, Merigliano C, Bonaccorsi S, El-Assawy
N, Priano L, Gai M, Berto GE, Chiotto AA, Sgrò F, Caramello A, Tasca L, Ala U, Neri F, Oliviero S,
Mauro A, Geley S, Gatti M, Di Cunto F. Citron Kinase Deficiency Leads to Chromosomal
Instability and TP53-Sensitive Microcephaly. Cell Rep. 2017;18: 1674 1686.
doi:10.1016/j.celrep.2017.01.054
24. Merigliano C, Marzio A, Renda F, Somma MP, Gatti M, Vernì F. A Role for the Twins Protein
Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity. Genetics.
2017;205: 1151 1167. doi:10.1534/genetics.116.192781
25. Cicconi A, Micheli E, Vernì F, Jackson A, Gradilla AC, Cipressa F, Raimondo D, Bosso G,
Wakefield JG, Ciapponi L, Cenci G, Gatti M, Cacchione S, Raffa GD. The Drosophila telomere
capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA
damage response. Nucleic Acids Res. 2017;45: 3068 3085. doi:10.1093/nar/gkw1244
26. Gai M, Bianchi FT, Vagnoni C, Vernì F, Bonaccorsi S, Pasquero S, Berto GE, Sgrò F, Chiotto
AA, Annaratone L, Sapino A, Bergo A, Landsberger N, Jacqueline Bond J, Huttner WB, Di Cunto
F. ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
EMBO Rep. 2017;18: 1870. doi:10.15252/embr.201745023
27. Vernì F, Cenci G. The Drosophila histone variant H2A.V works in concert with HP1 to
promote kinetochore-driven microtubule formation. Cell Cycle. 2015;14: 577 588.
doi:10.4161/15384101.2014.991176
28. Messina G, Damia E, Fanti L, Atterrato MT, Celauro E, Mariotti FR, Accardo MC, Walther
M, Vernì F, Picchioni D, Moschetti M, Caizzi R, Piacentini L, Cenci G, Giordano E, Dimitri P.
Yeti, an essential Drosophila melanogaster gene, encodes a protein required for chromatin
organization. J Cell Sci. 2014;127: 2577 2588. doi:10.1242/jcs.150243
29. Marzio A, Merigliano C, Gatti M, Vernì F. Sugar and chromosome stability: clastogenic
effects of sugars in vitamin B6-deficient cells. PLoS Genet. 2014;10: e1004199.
doi:10.1371/journal.pgen.1004199
30. Cipressa F, Romano S, Centonze S, zur Lage PI, Vernì F, Dimitri P, Gatti M, Cenci G. Effete, a
Drosophila chromatin-associated ubiquitin-conjugating enzyme that affects telomeric and
heterochromatic position effect variegation. Genetics. 2013;195: 147 158.
doi:10.1534/genetics.113.153320

Produzione scientifica

11573/218636 - 9999 - fascetto a Drosophila gene required for cytokinesis, encodes a protein homologous to mammalian PRCI.
Verni', Fiammetta; Somma, M. P.; Bonaccorsi, Silvia; Belloni, Giorgio; Gatti, Maurizio - 13a Altro ministeriale

11573/1709402 - 2024 - Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations
Liguori, Francesco; Alberti, Francesca; Amadio, Susanna; Francesca Angelini, Daniela; Pilesi, Eleonora; Vitale, Giuseppe; Tesoriere, Giulia; Borsellino, Giovanna; Verni, Fiammetta; Volonté, Cinzia - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE (Amsterdam: Elsevier) pp. - - issn: 1879-260X - wos: WOS:001236163900001 (2) - scopus: 2-s2.0-85191187542 (2)

11573/1711429 - 2024 - Vitamin B6 deficiency cooperates with oncogenic Ras to induce malignant tumors in Drosophila
Pilesi, Eleonora; Tesoriere, Giulia; Ferriero, Angelo; Mascolo, Elisa; Liguori, Francesco; Argirò, Luca; Angioli, Chiara; Tramonti, Angela; Contestabile, Roberto; Volontè, Cinzia; Verni, Fiammetta - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:001238258400004 (0) - scopus: 2-s2.0-85194997356 (0)

11573/1711430 - 2024 - Vitamin B6 and diabetes and its role in counteracting advanced glycation end products
Verni, Fiammetta - 02a Capitolo o Articolo
libro: Vitamins and hormones - ()

11573/1697329 - 2023 - IVV-11 Pan-neuronal expression of human SOD1 mutations in Drosophila induces early neuroinflammation
Liguori, F.; Alberti, F.; Amadio, S.; Angelini, D.; Pilesi, E.; Passaro, I.; Verni, Fiammetta; Volontè, C. - 04d Abstract in atti di convegno
congresso: 34th ALS/MND Symposium Basilea, 6-8 dicembre 2023 (Basilea, Swiss)
libro: (2023) Theme 04 - In Vivo Experimetal Models, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 24:sup1, 128-139, DOI: 10.1080/21678421.2023.2260194 - ()

11573/1681318 - 2023 - A gene-nutrient interaction between vitamin B6 and serine hydroxymethyltransferase (SHMT) affects genome integrity in Drosophila
Pilesi, Eleonora; Angioli, Chiara; Graziani, Claudio; Parroni, Alessia; Contestabile, Roberto; Tramonti, Angela; Verni', Fiammetta - 01a Articolo in rivista
rivista: JOURNAL OF CELLULAR PHYSIOLOGY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-9 - issn: 0021-9541 - wos: WOS:000985887600001 (2) - scopus: 2-s2.0-85159181495 (2)

11573/1640256 - 2022 - Vitamin B6 deficiency promotes loss of heterozygosity (LOH) at the Drosophila warts (wts) locus
Gnocchini, Eleonora; Pilesi, Eleonora; Schiano, Ludovica; Verni', Fiammetta - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-11 - issn: 1422-0067 - wos: WOS:000809126600001 (4) - scopus: 2-s2.0-85130780375 (5)

11573/1654072 - 2022 - Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP
La Torre, Mattia; Merigliano, Chiara; Maccaroni, Klizia; Chojnowski, Alexandre; Ing Goh, Wah; Giubettini, Maria; Verni', Fiammetta; Capanni, Cristina; Rhodes, Daniela; Wright, Graham; Burke, Brian; Soddu, Silvia; Burla, Romina; Saggio, Isabella - 01a Articolo in rivista
rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. - - issn: 1756-9966 - wos: WOS:000853082900001 (4) - scopus: 2-s2.0-85137716628 (5)

11573/1641668 - 2022 - Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K
Mascolo, Elisa; Liguori, Francesco; Merigliano, Chiara; Schiano, Ludovica; Gnocchini, Eleonora; Pilesi, Eleonora; Volontè, Cinzia; Di Salvo, Luigi Martino; Contestabile, Roberto; Tramonti, Angela; Vernì, Fiammetta - 01a Articolo in rivista
rivista: JOURNAL OF CELLULAR PHYSIOLOGY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0021-9541 - wos: WOS:000808170700001 (4) - scopus: 2-s2.0-85131575649 (5)

11573/1660228 - 2022 - DNA Damage Response (DDR) and DNA Repair
Verni', Fiammetta - 01m Editorial/Introduzione in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000822205000001 (7) - scopus: 2-s2.0-85132934074 (7)

11573/1582519 - 2021 - The genetics of diabetes: what we can learn from Drosophila
Liguori, Francesco; Mascolo, Elisa; Verni', Fiammetta - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000714723400001 (7) - scopus: 2-s2.0-85117194288 (11)

11573/1486133 - 2021 - Functional inactivation of drosophila GCK orthologs causes genomic instability and oxidative stress in a fly model of MODY-2
Mascolo, Elisa; Liguori, Francesco; Stufera Mecarelli, Lorenzo; Amoroso, Noemi; Merigliano, Chiara; Amadio, Susanna; Volonté, Cinzia; Contestabile, Roberto; Tramonti, Angela; Vernì, Fiammetta - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000611336600001 (7) - scopus: 2-s2.0-85100104845 (9)

11573/1567244 - 2021 - AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody
Merigliano, Chiara; Burla, Romina; La Torre, Mattia; Del Giudice, Simona; Teo, Hsiangling; Liew, Chong Wai; Chojnowski, Alexandre; Goh, Wah Ing; Olmos, Yolanda; Maccaroni, Klizia; Giubettini, Maria; Chiolo, Irene; Carlton, Jeremy G; Raimondo, Domenico; Vernì, Fiammetta; Stewart, Colin L; Rhodes, Daniela; Wright, Graham D; Burke, Brian E; Saggio, Isabella - 01a Articolo in rivista
rivista: PLOS GENETICS (San Francisco, CA : Public Library of Science, c2005-) pp. - - issn: 1553-7404 - wos: WOS:000692720600001 (13) - scopus: 2-s2.0-85114446003 (12)

11573/1441392 - 2020 - Interplay of the nuclear envelope with chromatin in physiology and pathology
Burla, R; La Torre, M; Maccaroni, K; Vernì, Fiammetta; Giunta, S; Saggio, I. - 01a Articolo in rivista
rivista: NUCLEUS (Austin, Tex. : Landes Bioscience) pp. 205-218 - issn: 1949-1034 - wos: WOS:000561995700001 (13) - scopus: 2-s2.0-85089748237 (19)

11573/1396007 - 2020 - The multifaceted role of vitamin b6 in cancer: drosophila as a model system to investigate dna damage
Contestabile, R.; Di Salvo, M. L.; Bunik, V.; Tramonti, A.; Verni, F. - 01a Articolo in rivista
rivista: OPEN BIOLOGY (London : Royal Society) pp. 200034- - issn: 2046-2441 - wos: WOS:000526945800001 (15) - scopus: 2-s2.0-85082380924 (17)

11573/1383443 - 2020 - X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics
Licursi, Valerio; Anzellotti, Silvia; Favaro, Jessica; Sineri, Serena; Carucci, Nicoletta; Cundari, Enrico; Fiore, Mario; Guarguaglini, Giulia; Pippa, Simone; Nisi, Paola S.; Verni', Fiammetta; Biagioni, Stefano; Cacci, Emanuele; Amendola, Roberto; Lupo, Giuseppe; Negri, Rodolfo - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000562147700003 (5) - scopus: 2-s2.0-85083477391 (6)

11573/1402415 - 2020 - Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms
Mascolo, Elisa; Verni', Fiammetta - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000539312100265 (72) - scopus: 2-s2.0-85085458233 (87)

11573/1358024 - 2020 - Changes in gene expression in human skeletal stem cells transduced with constitutively active Gsα correlates with hallmark histopathological changes seen in fibrous dysplastic bone
Raimondo, Domenico; Remoli, Cristina; Astrologo, Letizia; Burla, Romina; La Torre, Mattia; Verni', Fiammetta; Tagliafico, Enrico; Corsi, Alessandro; Del Giudice, Simona; Persichetti, Agnese; Giannicola, Giuseppe; Robey, Pamela G.; Riminucci, Mara; Saggio, Isabella - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000534612400014 (10) - scopus: 2-s2.0-85078709920 (9)

11573/1324356 - 2019 - The expression of four pyridoxal kinase (pdxk) human variants in drosophila impacts on genome integrity
Mascolo, E.; Barile, A.; Stufera Mecarelli, Lorenzo; Amoroso, N.; Merigliano, C.; Massimi, A.; Saggio, I.; Hansen, T.; Tramonti, A.; Di Salvo, M. L.; Barbetti, F.; Contestabile, R.; Verni', F. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000488481500051 (10) - scopus: 2-s2.0-85072935487 (11)

11573/1299581 - 2019 - Pyridoxine/pyridoxamine 5′‐phosphate oxidase (Sgll/PNPO)is important for DNA integrity and glucose homeostasis maintenance in Drosophila
Mascolo, Elisa; Amoroso, Noemi; Saggio, Isabella; Merigliano, Chiara; Verni', Fiammetta - 01a Articolo in rivista
rivista: JOURNAL OF CELLULAR PHYSIOLOGY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0021-9541 - wos: WOS:000485370700001 (18) - scopus: 2-s2.0-85072217732 (19)

11573/1211550 - 2019 - A new role for Drosophila Aurora-A in maintaining chromosome integrity
Merigliano, Chiara; Mascolo, Elisa; Cesta, Anthony; Saggio, Isabella; Vernì, Fiammetta - 01a Articolo in rivista
rivista: CHROMOSOMA (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 41-52 - issn: 0009-5915 - wos: WOS:000459275000006 (4) - scopus: 2-s2.0-85059522210 (4)

11573/1122355 - 2018 - Genomic instability and DNA replication defects in progeroid syndromes
Burla, Romina; La Torre, Mattia; Merigliano, Chiara; Verni', Fiammetta; Saggio, Isabella - 01a Articolo in rivista
rivista: NUCLEUS (Austin, Tex. : Landes Bioscience) pp. - - issn: 1949-1034 - wos: WOS:000446537800001 (33) - scopus: 2-s2.0-85054408727 (38)

11573/1200219 - 2018 - p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice
Burla, Romina; La Torre, Mattia; Zanetti, Giorgia; Bastianelli, Alex; Merigliano, Chiara; Del Giudice, Simona; Vercelli, Alessandro; Di Cunto, Ferdinando; Boido, Marina; Verni', Fiammetta; Saggio, Isabella - 01a Articolo in rivista
rivista: FRONTIERS IN GENETICS (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-8021 - wos: WOS:000451482300001 (9) - scopus: 2-s2.0-85077990827 (12)

11573/1090295 - 2018 - Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits
La Torre, Mattia; Merigliano, Chiara; Burla, Romina; Mottini, Carla; Zanetti, Giorgia; Del Giudice, Simona; Carcuro, Mariateresa; Ilaria, Virdia; Bucciarelli, Elisabetta; Isabella, Manni; Rampioni Vinciguerra, Gian Luca; Giulia, Piaggio; Riminucci, Mara; Ana, Cumano; Bartolazzi, Armando; Verni', Fiammetta; Silvia, Soddu; Gatti, Maurizio; Saggio, Isabella - 01a Articolo in rivista
rivista: AGING CELL ([Oxford] : Blackwell Science Ltd, 2002-) pp. - - issn: 1474-9726 - wos: WOS:000439767700002 (15) - scopus: 2-s2.0-85045190427 (15)

11573/1143773 - 2018 - The Relationship Between Vitamin B6, Diabetes and Cancer
Merigliano, Chiara; Mascolo, Elisa; Burla, Romina; Saggio, Isabella; Verni', Fiammetta - 01a Articolo in rivista
rivista: FRONTIERS IN GENETICS (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-8021 - wos: WOS:000444470900001 (42) - scopus: 2-s2.0-85055211222 (49)

11573/1136658 - 2018 - Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes
Merigliano, Chiara; Mascolo, Elisa; La Torre, Mattia; Saggio, Isabella; Verni', Fiammetta - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000440144400049 (26) - scopus: 2-s2.0-85050800899 (29)

11573/925229 - 2017 - The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response
Cicconi, Alessandro; Micheli, Emanuela; Verni', Fiammetta; Jackson, A; Gradilla, Ac; Cipressa, Francesca; Raimondo, Domenico; Bosso, Giuseppe; Wakefield, Jg; Ciapponi, Laura; Cenci, Giovanni; Gatti, Maurizio; Cacchione, Stefano; Raffa, Grazia Daniela - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 3068-3085 - issn: 0305-1048 - wos: WOS:000398376200022 (14) - scopus: 2-s2.0-85019962618 (16)

11573/955559 - 2017 - WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models
Di Giorgio, Maria Laura; Esposito, Alessandro; Maccallini, Paolo; Micheli, Emanuela; Bavasso, Francesca; Gallotta, Ivan; Verni', Fiammetta; Feiguin, Fabian; Cacchione, Stefano; Mccabe, Brian D.; Schiavi, Elia Di; Raffa, Grazia Daniela - 01a Articolo in rivista
rivista: NEUROBIOLOGY OF DISEASE (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 42-50 - issn: 0969-9961 - wos: WOS:000406734300004 (15) - scopus: 2-s2.0-85019703595 (15)

11573/933755 - 2017 - Citron Kinase Deficiency Leads to Chromosomal Instability and TP53-Sensitive Microcephaly
Federico Tommaso, Bianchi; Chiara, Tocco; Gianmarco, Pallavicini; Yifan, Liu; Verni', Fiammetta; Merigliano, Chiara; Bonaccorsi, Silvia; Nadia El, Assawy; Lorenzo, Priano; Marta, Gai; Gaia Elena, Berto; Alessandra Maria Adelaide, Chiotto; Francesco, Sgro; Alessia, Caramello; Laura, Tasca; Ugo, Ala; Francesco, Neri; Salvatore, Oliviero; Alessandro, Mauro; Stephan, Geley; Maurizio, Gatti; Ferdinando Di, Cunto - 01a Articolo in rivista
rivista: CELL REPORTS (Elsevier B.V. Cambridge MA: Cell Press) pp. 1674-1686 - issn: 2211-1247 - wos: WOS:000397324900010 (43) - scopus: 2-s2.0-85013159186 (43)

11573/933281 - 2017 - A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity
Merigliano, Chiara; Antonio Marzio, 1; Fioranna Renda, 2; Maria Patrizia Somma, 3; Gatti, Maurizio; Verni', Fiammetta - 01a Articolo in rivista
rivista: GENETICS (Genetics Society of America:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7029, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728) pp. 1151-1167 - issn: 0016-6731 - wos: WOS:000395807200012 (22) - scopus: 2-s2.0-85020319410 (22)

11573/922987 - 2016 - ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules
Gai, Marta; Bianchi, Federico T; Vagnoni, Cristiana; Verni', Fiammetta; Bonaccorsi, Silvia; Pasquero, Selina; Berto, Gaia E; Sgrò, Francesco; Chiotto, Alessandra Ma; Annaratone, Laura; Sapino, Anna; Bergo, Anna; Landsberger, Nicoletta; Bond, Jacqueline; Huttner, Wieland B; Di Cunto, Ferdinando - 01a Articolo in rivista
rivista: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 1396-1409 - issn: 1469-221X - wos: WOS:000385710000005 (47) - scopus: 2-s2.0-84989905489 (54)

11573/772214 - 2015 - The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation
Verni', Fiammetta; Cenci, Giovanni - 01a Articolo in rivista
rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 577-588 - issn: 1538-4101 - wos: WOS:000350137700020 (12) - scopus: 2-s2.0-84923605889 (11)

11573/540470 - 2014 - Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells
Marzio, Antonio; Merigliano, Chiara; Gatti, Maurizio; Verni', Fiammetta - 01a Articolo in rivista
rivista: PLOS GENETICS (San Francisco, CA : Public Library of Science, c2005-) pp. - - issn: 1553-7404 - wos: WOS:000337144700028 (34) - scopus: 2-s2.0-84897403895 (39)

11573/548882 - 2014 - Yeti, an essential Drosophila melanogaster gene, encodes a protein required for chromatin organization
Messina, Giovanni; Elisabetta, Damia; Fanti, Laura; M. T., Atterrato; Celauro, Emanuele; Accardo, Maria Carmela; Mariotti, Francesca Romana; M., Walter; Verni', Fiammetta; D., Picchioni; R., Moschetti; R., Caizzi; Piacentini, Lucia; Cenci, Giovanni; E., Giordano; Dimitri, Patrizio - 01a Articolo in rivista
rivista: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 2577-2588 - issn: 0021-9533 - wos: WOS:000337217400019 (28) - scopus: 2-s2.0-84901800943 (28)

11573/763324 - 2014 - PRINCIPI DI GENETICA
S., Aceto; Ciapponi, Laura; S., Dolfini; R., Elli; D., Ghisotti; E., Giordano; R., Mantovani; L., Marcucci; P. V., Riva; G., Saccone; Saggio, Isabella; M., Venturin; Verni', Fiammetta - 03e Traduzione di libro
libro: Principi di genetica - D.P. Snustad, M.J. Simmons ()

11573/519585 - 2013 - Effete, an E2 ubiquitin-conjugating enzyme with multiple roles in Drosophila development and chromatin organization
Cipressa, Francesca; S., Romano; S., Centonze; P. I., Zur; Verni', Fiammetta; Dimitri, Patrizio; Gatti, Maurizio; Cenci, Giovanni - 01a Articolo in rivista
rivista: GENETICS (Genetics Society of America:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7029, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728) pp. 147-158 - issn: 0016-6731 - wos: WOS:000324174200012 (11) - scopus: 2-s2.0-84883774006 (12)

11573/413121 - 2011 - Phenotypic analysis of misato function reveals roles of noncentrosomal microtubules in Drosophila spindle formation
V., Mottier Pavie; Cenci, Giovanni; Verni', Fiammetta; Gatti, Maurizio; Bonaccorsi, Silvia - 01a Articolo in rivista
rivista: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 706-717 - issn: 0021-9533 - wos: WOS:000287307000006 (17) - scopus: 2-s2.0-79952777567 (18)

11573/359937 - 2008 - Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference.
Somma, M. P.; Ceprani, Francesca; Bucciarelli, E.; Naim, Valeria; De Arcangelis, V.; Piergentili, Roberto; Palena, A.; Ciapponi, Laura; Giansanti, M. G.; Pellacani, Claudia; Petrucci, Romano; Cenci, Giovanni; Verni', Fiammetta; Fasulo, Barbara; Goldberg, M. L.; Di Cunto, F.; Gatti, Maurizio - 01a Articolo in rivista
rivista: PLOS GENETICS (San Francisco, CA : Public Library of Science, c2005-) pp. 1-18 - issn: 1553-7390 - wos: WOS:000260410600011 (66) - scopus: 2-s2.0-48249153027 (66)

11573/69191 - 2007 - Drosophila melanogaster as a model for studying protein-encoding genes that are resident in constitutive heterochromatin
Nicoletta, Corradini; Rossi, Fabrizio; E., Giordano; R., Caizzi; Verni', Fiammetta; Dimitri, Patrizio - 01a Articolo in rivista
rivista: HEREDITY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 3-12 - issn: 0018-067X - wos: WOS:000242851000002 (13) - scopus: 2-s2.0-33845794290 (14)

11573/236964 - 2005 - The paradox of functional heterochromatin
Dimitri, Patrizio; Corradini, N.; Rossi, F.; Verni', Fiammetta - 01a Articolo in rivista
rivista: BIOESSAYS (-HOBOKEN, USA, NJ: JOHN WILEY & SONS INC -Cambridge : Cambridge University Press, 1984-) pp. 29-41 - issn: 0265-9247 - wos: WOS:000226083200006 (55) - scopus: 2-s2.0-12344298627 (61)

11573/69189 - 2005 - Transposable elements as artisans of the heterochromatic genome in Drosophila melanogaster
Dimitri, Patrizio; Corradini, N; Mei, E; Rossi, F; Zhimulev, I. F; Verni', Fiammetta - 01a Articolo in rivista
rivista: CYTOGENETIC AND GENOME RESEARCH (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 165-172 - issn: 1424-8581 - wos: WOS:000231064600017 (11) - scopus: 2-s2.0-23844523785 (12)

11573/239825 - 2004 - Feo, the Drosophila homolog of PRC1, is required for central spindle formation and cytokinesis
Verni', Fiammetta; Somma, M. P.; Gunsalus, K. C.; Bonaccorsi, Silvia; Belloni, Giorgio; Goldberg, M. L.; Gatti, Maurizio - 01a Articolo in rivista
rivista: CURRENT BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 1569-1575 - issn: 0960-9822 - wos: WOS:000223813500023 (92) - scopus: 2-s2.0-4644243831 (93)

11573/210876 - 2003 - Known and predicted genes in the heterochromatin of Drosophila melanogaster.
Corradini, N.; Rossi, F.; Verni, F.; Dimitri, Patrizio - 04a Atto di comunicazione a congresso
congresso: Sixth international conference on Drosophila heterochromatin (Ravello)
libro: Sixth international conference on Drosophila heterochromatin, Ravello - ()

11573/42750 - 2003 - FISH analysis of Drosophila melanogaster heterochromatin using BACs and P-elements.
Corradini, N.; Rossi, F.; Verni', Fiammetta; Dimitri, Patrizio - 01a Articolo in rivista
rivista: CHROMOSOMA (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 26-37 - issn: 0009-5915 - wos: WOS:000184326000004 (23) - scopus: 2-s2.0-1542546220 (25)

11573/69001 - 2003 - FISH analysis of Drosophila heterochromatin using BACs and P-elements.
Corradini, N; F., Rossi; Verni, F.; Dimitri, Patrizio - 01a Articolo in rivista
rivista: CHROMOSOMA (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 26-37 - issn: 0009-5915 - wos: (0) - scopus: (0)

11573/42749 - 2003 - Vital genes in the heterochromatin of chromosomes 2 and 3 of Drosophila melanogaster
Dimitri, Patrizio; Nicoletta, Corradini; F., Rossi; Verni', Fiammetta; Cenci, Giovanni; Belloni, Giorgio; I. F., Zhimulev; D. E., Koryakov - 01a Articolo in rivista
rivista: GENETICA (Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. 209-215 - issn: 0016-6707 - wos: WOS:000181857500011 (18) - scopus: 2-s2.0-0012748071 (20)
congresso: 5th International Conference on Drosophila Heterochromatin (CORTONA, ITALY)

11573/43256 - 2001 - Male sterile mutant casanova gives clues to mechanisms of sperm-egg interactions in Drosophila melanogaster.
Perotti, Me; Cattaneo, F; Pasini, Me; Verni', Fiammetta; Hackstein, J. H. - 01a Articolo in rivista
rivista: MOLECULAR REPRODUCTION AND DEVELOPMENT (New York N.Y.: Wiley) pp. 48-59 - issn: 1040-452X - wos: WOS:000170917500016 (42) - scopus: 2-s2.0-0034855620 (47)

11573/5593 - 2000 - Genetic and molecular analysis of wing apart-like (wapl), a gene controlling heterochromatin organization in Drosophila melanogaster.
Verni', Fiammetta; Gandhi, R.; Goldberg, M. L.; Gatti, Maurizio - 01a Articolo in rivista
rivista: GENETICS (Genetics Society of America:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7029, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728) pp. 1693-1710 - issn: 0016-6731 - wos: WOS:000086491000023 (69) - scopus: 2-s2.0-0034117543 (72)

11573/163666 - 1997 - Genes controlling chromosome structure in Drosophila melanogaster.
Verni', Fiammetta; Somma, M. P.; Gandhi, R.; Goldberg, M. L.; Gatti, Maurizio - 02a Capitolo o Articolo
libro: Chromosomes Today - ()

11573/7197 - 1995 - Mutations in twinstar, a Drosophila gene encoding a cofilin/ADF homologue, result in defects in centrosome migration and cytokinesis
K. C., Gunsalus; Bonaccorsi, Silvia; E., Williams; Verni', Fiammetta; Gatti, Maurizio; M. L., Goldberg - 01a Articolo in rivista
rivista: THE JOURNAL OF CELL BIOLOGY (Rockefeller University Press:1114 First Avenue, Fourth Floor:New York, NY 10021:(212)327-8572, EMAIL: rupcd@rockvax.rockefeller.edu, INTERNET: http://www.rockefeller.edu/rupress, Fax: (212)327-7944) pp. 1243-1259 - issn: 0021-9525 - wos: WOS:A1995TJ29500011 (257) - scopus: 2-s2.0-0028799957 (261)

11573/247466 - 1994 - Chromatin and microtuble organization during premeiotic, meiotic and early postmeiotic stages of Drosophila melanogaster spermatogenesis
Cenci, Giovanni; Bonaccorsi, Silvia; Pisano, Claudio; Verni', Fiammetta; Gatti, Maurizio - 01a Articolo in rivista
rivista: JOURNAL OF CELL SCIENCE (The Company of Biologists Limited:Bidder Building, 140 Cowley Road, Cambridge CB4 0DL United Kingdom:011 44 1223 420482, EMAIL: mandy@thecob.demon.co.uk, INTERNET: http://www.biologists.com, Fax: 011 44 1223 423353) pp. 3521-3534 - issn: 0021-9533 - wos: WOS:A1994QB17500024 (172) - scopus: 2-s2.0-0028556680 (168)

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