FEDERICA D'ANTONIO

PhD Student

PhD program:: XXXVIII
email: f.dantonio@uniroma1.it




supervisor: Prof. Angela Mastronuzzi

D’ Antonio Federica

POSITION
Medical Oncology, Ph.D. Network Oncology and Precision Medicine at Sapienza University Rome. Medical oncology at Bambino Gesù Hospital Rome


WORK EXPERIENCE
12/2017-01/23 Oncology residency at Humanitas Cancer Center, Humanitas University (Rozzano). Tutor/Mentor: Prof. A. Santoro, Prof. Paolo Andrea Zucali, Dr.ssa Angela Mastronuzzi. I worked mainly in pediatric neuro-oncology, genitourinary and rare cancer fields, clinical phase I, II, and III trials.

EDUCATION

22/07/2016 Degree in Medicine at Campus Biomedico in Rome with magna cum laude mark.

01/12/2012-01/12/2013 Human Physiology tutor Campus Biomedico University, Department of Neuroscience, collaborating with prof Flavio Keller


02/2014-01/02/2015 Traineeship in Internal Medicine Campus Biomedico University with prof R.Antonelli Incalzi

02/2015-10/2017 Traineeship in Medical Oncology Campus Biomedico University with prof D.Santini and G.Tonini

08/2015-11/2015 Erasmus Traineeship in Medical Oncology Hospital Clínico, tutor prof. Andrés Cervantes, Valencia (Spain)

05/2016-08/2016 Traineeship in Pediatric Oncology A.Gemelli Umiversity in Rome with prof. Pietro Valentini

08/2016-12/2016 Internship in Medical Oncology at the Antwerp University (Belgium)
UZA Hospital, Tutor prof. Christian Rolfo

05/2018 Speaker at ESMO Precentorship on AYA Malignancies Lugano

11/2018 Speaker at ESMO Precentorship on Immune-oncology Zurig

11/2018 ESMO Presentation Cardio-Oncology “Predictors of cardiac toxicity in HER2 positive Breast Cancer patients on trastuzumab”

10/2019 ESMO Poster presentation ”Pathological down staging in patients with “Primary” or “Secondary” Muscle-invasive Bladder Cancer after neo-adjuvant platinum-based chemotherapy: a retrospective analysis.”

10/2020 ESMO/AIOM Poster “Invasive urothelial carcinoma and neural phenotype: alternative score detection (Piescore)” and prognostic implications.”

01/2021-12/2022 Internship in Pediatric neuro-oncology at Bambino Gesù Hospital Rome, Tutor Dr.ssa Angela Mastronuzzi, Prof. Franco Locatelli


MOTHER TONGUE
Italian
OTHER LANGUAGES
COMPREHENSION SPOKEN WRITTEN
Listening Reading Interaction oral
ENGLISH C1 C1 B2 B2 B2
Levels: A1 e A2: Basic - B1 e B2: User Self - C1 e C2: Advanced


Communication skill Excellent communication skills acquired during the studies at the University of Medicine and in performing personal activities (for example: personal hobby, large family enterprise)
Excellent exhibition skills.

Organizational and management skill: High level of Leadership skills
Outstanding competencies for team building

Digital skill User Self Office Suite, Stata


PUBBLICATION

Molecular Profiling of Pancreatic Neuroendocrine Tumors (pNETS) and the Clinical Potential Massimiliano Camilli, Konstantinos Papadimitriou, Amanda Nogueira, Lorena Incorvaia, Antonio Galvano, Federica D'Antonio, Jose Ferri, Daniele Santini, Nicola Silvestris, Antonio Russo, Marc Peeters, Christian Rolfo

A phase II study of the combination of gemcitabine and imatinib mesylate in pemetrexed-pretreated patients with malignant pleural mesothelioma.Zucali PA, Perrino M, De Vincenzo F, Giordano L, Cordua N, D'Antonio F, Santoro A. Lung Cancer. 2020 Apr


Pulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity: A case report on the therapeutic regimen. D'Antonio F, De Sanctis R, Bolengo I, Destro A, Rahal D, De Vincenzo F, Santoro A.Medicine (Baltimore). 2019 Aug;98(32)


Genomewide Association Study of Severe Covid-19 with Respiratory Failure.
David Ellinghaus, Ph.D., Frauke Degenhardt, M.Sc., Luis Bujanda, M.D., Ph.D., Maria Buti, M.D. et al.NEJM 2020 Jun 17

Current Perspectives on Immunotherapy in the Peri-Operative Setting of Muscle-Infiltrating Bladder Cancer. Paolo Andrea Zucali, Nadia Cordua, Federica D'Antonio, Federica Borea, Matteo Perrino, Fabio De Vincenzo, Armando Santoro 2020 Oct 21. Front Oncol.

Resound Trial: A phase 2 study of regorafenib in patients with thymoma (type B2-B3) and thymic carcinoma previously treated with chemotherapy.Perrino M, De Pas T, Bozzarelli S, Giordano L, De Vincenzo F, Conforti F, Digiacomo N, Cordua N, D'Antonio F, Borea F, Santoro A, Zucali PA.
Cancer. 2021 Oct 27

Baseline Characteristics and Outcomes of Cancer Patients Infected with SARS-CoV-2 in the Lombardy Region, Italy (AIOM-L CORONA): A Multicenter, Observational, Ambispective, Cohort Study.Di Cosimo S, Tagliaferri B, Generali D, Giudici F, Agustoni F, Bernardo A, Borgonovo K, Farina G, Luchena G, Luciani A, Nolè F, Palmeri L, Pietrantonio F, Poggi G, Zucali PA, Balletti E, Catania G, Bernocchi O, D'Antonio F, Giordano M, Grossi F, Lasagna A, La Verde N, Manzoni M, Montagna B, Olgiati A, Raimondi A, Rampinelli I, Verri E, Zaniboni A, Di Maio M, Beretta G, Danova M.Cancers (Basel). 2021 Mar

Clinical predictors of cardiac toxicity in HER2-positive early breast cancer patients treated with adjuvant s.c. versus i.v. trastuzumab Rita De Sanctis 1, Laura Giordano , Federica D'Antonio, Elisa Agostinetto, Arianna Marinello, Daniela Guiducci,Giovanna Masci, Agnese Losurdo, Monica Zuradelli, Rosalba Torrisi, Armando Santoro.

Systemic treatments for recurrent thymic tumours Authors: Paolo Andrea Zucali, Federica D'Antonio, Nadia Cordua, Federica Borea, Matteo Perrino, Fabio De Vincenzo, Armando Santoro

Advances in drug treatments for mesothelioma. Zucali PA, De Vincenzo F, Perrino M, Digiacomo N, Cordua N, D'Antonio F, Borea F, Fazio R, Pirozzi A, Santoro A.


SARS-CoV-2 vaccine in patients with thymic epithelial tumours with and without active or pre-existing autoimmune disorders: Brief report of a TYME network safety analysis Federica Giugliano, Paolo A Zucali et al. Eur J Cancer 2022 May

Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer
Cancers (Basel) 2022 Jul 2;

Prognostic Significance of Organ-Specific Metastases in Patients with Metastatic Upper Tract Urothelial Carcinoma.
Tufano A, Cordua N, Nardone V, Ranavolo R, Flammia RS, D'Antonio F, Borea F, Anceschi U, Leonardo C, Morrione A, Giordano A. Cancers (Basel) 2022 Jul 2.



PUBLICATION ongoing
A case of misdiagnosed metastatic intracranial myxoid angiomatoid fibrous histiocytoma treated with multimodal tailored therapy.

Projects
Relationship between circulating PD-L1 and Granzyme B and response to immune checkpoint inhibitors: a retrospective analysis’ Authors: Federica D’Antonio, Paolo Andrea Zucali, Egesta Lopci, Matteo Perrino, Fabio De Vincenzo, Nadia Cordua, , Federica Borea, Armando Santoro

Real-life data on the cardiac safety profile in AYA patients treated with intravenous Anthracycline

Certification
Basic Life Support Defibrillator (BLS-D) Certification Course (06/2020) American Heart Association
Intermediate Life Support (ILS), Italian Resuscitation Council

Department of Biomedical Sciences, Humanitas University Seminar: Advanced Topics in Biostatistics: Regression & Survival Analysis» Faculty Stefanos Bonovas, MD, MSc, PhD. Assistant Professor of Medical Statistics, Humanitas University.
Pediatric Advanced Life Support (PALS)American Heart Association Certification Course (11/2022)















Research products

11573/1667749 - 2022 - Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer
De Carlo, Camilla; Valeri, Marina; Rudini, Noemi; Zucali, Paolo Andrea; Cieri, Miriam; Elefante, Grazia Maria; D'antonio, Federica; Hurle, Rodolfo; Giordano, Laura; Bressan, Alessandra; Lazzeri, Massimo; Perrino, Matteo; Guazzoni, Giorgio; Terracciano, Luigi Maria; Colombo, Piergiuseppe - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000822105700001 (1) - scopus: 2-s2.0-85133944313 (2)

11573/1683463 - 2022 - Impact of chronic exposure to 5-alpha reductase inhibitors on the risk of hospitalization for COVID-19: a case-control study in male population from two COVID-19 regional centers of Lombardy, Italy
Lazzeri, Massimo; Duga, Stefano; Azzolini, Elena; Fasulo, Vittorio; Buffi, Nicolò; Saita, Alberto; Lughezzani, Giovanni; Paraboschi, Elvezia M; Hurle, Rodolfo; Nobili, Alessandro; Cecconi, Maurizio; Guazzoni, Giorgio; Casale, Paolo; Asselta, Rosannam; D'antonio, Federica - 01a Articolo in rivista
paper: MINERVA UROLOGY AND NEPHROLOGY (Torino: Minerva medica) pp. 77-84 - issn: 2724-6051 - wos: WOS:000768297300011 (2) - scopus: 2-s2.0-85126389556 (5)

11573/1667759 - 2022 - Resound Trial: A phase 2 study of regorafenib in patients with thymoma (type B2-B3) and thymic carcinoma previously treated with chemotherapy
Perrino, Matteo; De Pas, Tommaso; Bozzarelli, Silvia; Giordano, Laura; De Vincenzo, Fabio; Conforti, Fabio; Digiacomo, Nunzio; Cordua, Nadia; D'antonio, Federica; Borea, Federica; Santoro, Armando; Zucali, Paolo Andrea - 01a Articolo in rivista
paper: CANCER ([New York, NY : John Wiley & Sons] : American Cancer Society) pp. 719-726 - issn: 1097-0142 - wos: WOS:000711603600001 (11) - scopus: 2-s2.0-85118208983 (11)

11573/1683460 - 2022 - Advances in drug treatments for mesothelioma
Zucali, Paolo Andrea; De Vincenzo, Fabio; Perrino, Matteo; Digiacomo, Nunzio; Cordua, Nadia; D'antonio, Federica; Borea, Federica; Fazio, Roberta; Pirozzi, Angelo; Santoro, Armando - 01a Articolo in rivista
paper: EXPERT OPINION ON PHARMACOTHERAPY (London : Ashley Publications [London] : Informa Healthcare) pp. 929-946 - issn: 1744-7666 - wos: WOS:000792676100001 (2) - scopus: 2-s2.0-85130144672 (2)

11573/1667761 - 2021 - Clinical predictors of cardiac toxicity in HER2-positive early breast cancer patients treated with adjuvant s.c. versus i.v. trastuzumab
De Sanctis, Rita; Giordano, Laura; D'antonio, Federica; Agostinetto, Elisa; Marinello, Arianna; Guiducci, Daniela; Masci, Giovanna; Losurdo, Agnese; Zuradelli, Monica; Torrisi, Rosalba; Santoro, Armando - 01a Articolo in rivista
paper: BREAST (Amsterdam: Elsevier [London]: Harcourt Publishers) pp. 80-85 - issn: 1532-3080 - wos: WOS:000694866500009 (6) - scopus: 2-s2.0-85103277121 (6)

11573/1683461 - 2021 - Systemic treatments for thymic tumors: a narrative review
Zucali, Paolo Andrea; De Vincenzo, Fabio; Perrino, Matteo; Digiacomo, Nunzio; Cordua, Nadia; D'antonio, Federica; Borea, Federica; Santoro, Armando - 01a Articolo in rivista
paper: MEDIASTINUM (Hong Kong: AME Publishing) pp. 24-24 - issn: 2522-6711 - wos: (0) - scopus: 2-s2.0-85115321728 (8)

11573/1667771 - 2020 - A phase II study of the combination of gemcitabine and imatinib mesylate in pemetrexed-pretreated patients with malignant pleural mesothelioma
Zucali, Paolo Andrea; Perrino, Matteo; De Vincenzo, Fabio; Giordano, Laura; Cordua, Nadia; D'antonio, Federica; Santoro, Armando - 01a Articolo in rivista
paper: LUNG CANCER (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 132-137 - issn: 0169-5002 - wos: WOS:000526981600020 (5) - scopus: 2-s2.0-85080085587 (5)

11573/1667775 - 2019 - Pulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity: A case report on the therapeutic regimen
D'antonio, Federica; De Sanctis, Rita; Bolengo, Isabella; Destro, Annarita; Rahal, Daoud; De Vincenzo, Fabio; Santoro, Armando - 01a Articolo in rivista
paper: MEDICINE (-Wolters Kluwer Health, -Philadelphia : Lippincott, Williams & Wilkins) pp. e16754- - issn: 0025-7974 - wos: WOS:000483262500051 (6) - scopus: 2-s2.0-85070540519 (6)



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