FEDERICA CONTE



email: federica.conte@iasi.cnr.it




CURRENT POSITION Permanent contract as Researcher, focus on Biomedical Engineering and Bioinformatics Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI) National Research Council, Rome (Italy) Role: Researcher - III professional level WORK EXPERIENCE 21/12/2022 – 21/03/2023 Research collaboration Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI) National Research Council, Rome (Italy) Role: Research collaborator Project title: "Analisi computazionali e statistiche nell’ambito del progetto SUMMa: Smart Urban Mobility" Advisor: Mauro Mazzei Main activities: Application of computational and statistical methods for the analysis and integration of big data Protocol number: Prot. n. 0001191 of 21/12/2022 16/02/2022 – 20/12/2022 Research collaboration Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI) National Research Council, Rome (Italy) Role: Research collaborator Project title: Bioinformatics analysis for “Bando PRIN 2017 – Settore ERC LS2 - Codice Progetto 20178L3P38 - Regulation of gene expression in grapevine: analysis of genetic and epigenetic determinants” Advisor: Paola Paci Main activities: Analysis and integration of grapevine data Protocol number: Prot. n. 0000111 of 16/02/2022, Prot. n. 0000484 of 19/05/2022, Prot. n. 0000824 of 20/09/2022 2/11/2017 – 1/11/2021 Post-doctoral research fellowship Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI) National Research Council, Rome (Italy) Role: Post-Doc Project title: Bioinformatics analysis and systems biology approach for the study of human cancers and neurodegenerative diseases Advisor: Paola Paci Main activities: Study and development of computational models and bioinformatics tools to analyze data of human cancers and neurodegenerative diseases Protocol number: Prot. n. 0000841 of 02/11/2017 02/11/2018 — 02/05/2019 Research collaboration ACT Operations Research (ACTOR) Rome (Italy) Role: Biomedical Engineer Project title: Development of models for the early and non-invasive diagnosis of neurodegenerative diseases (MoDiag Project) Main activities: Development, study and application of mathematical models and computational algorithms in the context of neurodegenerative diseases with a high social and economic impact; Integrated analysis of different kinds of biological data 2/11/2015 – 31/10/2017 Post-doctoral research fellowship Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI) National Research Council, Rome (Italy) Role: Post-Doc Project title: A bioinformatic approach to the development of cancer biomarkers via mirna regulation network (cerna) and transcripts stability control Advisor: Paola Paci Main activities: Study and development of computational models to analyze biological data within the EPIGEN Flagship project Protocol number: Prot. n. 0000634 of 30/10/2015 EDUCATION AND TRAINING 01/11/2012 -– 31/10/2015 PhD in Automatica and Operations Research Department of Computer, Control and Management Engineering (DIAG) Sapienza University of Rome Dissertation title: Insulin signaling network: mathematical modeling and parameter estimation from experimental data Advisor (DIAG): Prof. Serenella Salinari Tutor (IASI-CNR): Dr. Alessandro Bertuzzi Final grade: Excellent Dissertation date: 23/05/2016 Main activities: Study of a mathematical model for the insulin signaling pathways and parameter estimation from experimental data 2010 — 2012 Master Degree in Biomedical Engineering Sapienza University of Rome Ingeneria Biomedica classe LM-21 [LM - Ordin. 2010] (D.M. 270/04) Dissertation title: Optimization of the protocol of tumour radiotherapy Advisor: Prof. Carlo Bruni Co-advisor: Drs. Carmela Sinisgalli, Dr. Federico Papa Final grade: 110/110 summa cum laude Dissertation date: 28/03/2012 2007 — 2010 Bachelor Degree in Clinical Engineering Sapienza University of Rome Ingeneria Clinica classe 10 [L-509 - Ordin. 2002] (D.M. 509/99) Dissertation title: Study of models for the regulation of glucose and insulin concentration in the blood: analysis of possible insulin therapy Advisor: Prof. Daniela Iacoviello Final grade: 110/110 Dissertation date: 22/01/2010 HONORS AND AWARDS 2018 Best Poster Award of the Bioinformatics Italian Society (BITS) at the 15th Annual Meeting of the Bioinformatics Italian Society - BITS2018, Turin (Italy) AUTHORS: Federica Conte, Giulia Fiscon, Paola Paci TITLE: Computational analysis to study the long non-coding RNAs associated ceRNA activity in human breast cancer 2017 Best Poster Award of the IEEE Technical Committee on Computational LifeScience Society (TCCLS) at Lipari School 2017 on Computational Drug Science and High-Precision Medicine AUTHORS: Federica Conte, Giulia Fiscon, Paola Paci TITLE: Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer TEACHING EXPERIENCE a.y. 2020–2023 “Cultore della materia” and teaching assistant for Bioingengeria per la Genomica course (6 CFU - SSD ING-INF/06) at Master Degree program in Biomedical Engineering of Department of Civil and Industrial Engineering, Sapienza University of Rome. “Cultore della materia”and teaching assistant for Bioinformatics II course (6 CFU - SSD INGINF/06) at Bachelor Degree program in Bioinformatics, Sapienza University of Rome (English course). “Cultore della materia” for Modelling and simulation of biomolecular dynamic systems course (6 CFU - SSD ING-INF/06) at Bachelor Degree program in Bioinformatics, Sapienza University of Rome (English course). a.y. 2019–2020 Teaching assistant for Bioingengeria per la Genomica course (6 CFU - SSD ING-INF/06) at Master Degree program in Biomedical Engineering of Department of Civil and Industrial Engineering, Sapienza University of Rome. a.y. 2017–2018 Adjunct Professor for Computational Biology course (6 CFU - SSD ING-INF/06) at Master Degree in Genetics and Molecular Biology at Sapienza University of Rome (English course). a.y. 2016–2017 Series of lectures for Molecular biology of mental processes course (6 CFU - SSD BIO/11) of Master Degree program in Neurobiology, Department of Mathematics, Physics and Natural science, Sapienza University of Rome. Series of Bioinformatics lectures for Biology of the cell course (6 CFU - SSD BIO/13) of Bachelor Degree program in Bioinformatics, Sapienza University of Rome (English course). Teaching assistant for Computational Biology course (6 CFU - SSD ING-INF/06) at Master Degree in Genetics and Molecular Biology at Sapienza University of Rome (English course). a.y. 2015–2016 Teaching assistant for for Biologia Computazionale course (6 CFU - SSD ING-INF/06) at Master Degree in Genetics and Molecular Biology at Sapienza University of Rome. ORAL PRESENTATIONS Sept 2023 12th Probiotics, Prebiotics and New Foods, Nutraceuticals and Botanicals for Nutrition and Human and Microbiota Health. – September 16th-19th 2023, Università Urbaniana, Rome (Italy). ROLE: Invited Speaker for the Session “Autism and gut/oral microbiome" PRESENTATION TITLE: Network-based data analyses for studying human diseases: autism spectrum disorders (ASDs). Sept 2023 14th Scientific Meeting of The CLAssification and Data Analysis Group of the Italian Statistical Society. CLADAG 2023 – September 11st-13rd 2023, Salerno (Italy). ROLE: Invited Speaker for the Session “Networks and higher-order networks data analysis and applications" PRESENTATION TITLE: The broad phenotype-specific applications of the network-based SWIM tool. Sept 2022 7th Global Insight Conference on BREAST CANCER. GICBC 2022 – September 20th-21st 2022, Barcelona (Spain). ROLE: Invited Speaker PRESENTATION TITLE: In silico recognition of a prognostic signature in basal-like breast cancer patients. Jun 2022 La Statistica al CNR al servizio del Paese – July 5th 2022. ROLE: Invited Speaker PRESENTATION TITLE: In silico recognition of a prognostic signature in basal-like breast cancer patients. Sept 2021 Mathematical Modelling and Control for Healthcare and Biomedical Systems. Virtual Workshop – September 28th-30th 2021. ROLE: Speaker PRESENTATION TITLE: Recognition of gene signatures in breast cancer subtypes. Sept 2021 11th Probiotics, Prebiotics & New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health – September 12th-14th 2021, Università Urbaniana, Rome (Italy). ROLE: Speaker PRESENTATION TITLE: Network-Based Approaches for the Identification of Complex Disease: Signature from Omics Data. Sept 2021 AUTOMATICA.IT 2021 workshop – September 8th-10th 2021, Catania (Italy). ROLE: Speaker PRESENTATION TITLE: The New Paradigm of Network Medicine to Analyze Breast Cancer Phenotypes. Jul 2021 BITS 2021- Annual Meeting of the Bioinformatics Italian Society – July 1st-2nd 2021. ROLE: Speaker PRESENTATION TITLE: The New Paradigm of Network Medicine to Analyze Breast Cancer Phenotypes. POSTERS Jun 2023 VIII CONGRESSO DEL GRUPPO NAZIONALE DI BIOINGEGNERIA - GNB 2023, June 21st-23rd 2023, Paduva (Italia). AUTHORS: Federica Conte, Giulia Fiscon, Paola Paci TITLE: Bioinformatics analyses to identify molecular gene signatures associated with breast cancer phenotypes. Dec 2018 ARTIFICIAL INTELLIGENCE AND HEALTH CONFERENCE, December 14th 2018, Rome (Italy). AUTHORS: Eleonora Cappelli, Federica Conte, Fabio Cumbo, Giulia Fiscon. TITLE: Combining knowledge-based approach with logic data mining techniques to improve data querying and analysis on Alzheimer’s Disease Data. Oct 028 ATA 2018 – 88th Annual Meeting of the American Thyroid Association, October 3rd-7th 2018, Washington,DC (USA). AUTHORS: Rosa Falcone, Paola Paci, Antonella Verrienti, Giulia Fiscon, Maria Luisa Sponziello, Federica Conte, Valeria Pecce, Francesca Rosignolo, Giorgio Grani, Livia Lamartina, Valeria Ramundo, Cosimo Durante, Lorenzo Farina, Sebastiano Filetti. TITLE: Network analysis of expression profiling data in papillary thyroid cancer. Sept 2018 THE FIRST INTERNATIONAL CONFERENCE ON NETWORK MEDICINE AND BIG DATA: The Transformation of Medicine, September 24th-26th 2018, Sapienza University of Rome (Italy). AUTHORS: Paola Paci, Giulia Fiscon, Federica Conte, Lorenzo Farina. TITLE: SWIM tool identifies specific genes controlling glioblastoma stem-like cells fate. Jun 2018 BITS 2018 – 15th Annual Meeting of the Bioinformatics Italian Society, June 27th-29th 2018, Turin (Italy). [Best poster award]. AUTHORS: Giulia Fiscon, Federica Conte, Paola Paci. TITLE: SWIM tool identifies specific genes controlling glioblastoma stem-like cells fate. Jun 2018 BITS 2018 – 15th Annual Meeting of the Bioinformatics Italian Society, June 27th-29th 2018, Turin (Italy). [Best poster award]. AUTHORS: Federica Conte, Giulia Fiscon, Paola Paci. TITLE: Computational analysis to study the long non-coding RNAs associated ceRNA activity in human breast cancer. Jul 2017 LIPARI SCHOOL ON COMPUTATIONAL DRUG SCIENCE AND HIGH-PRECISION MEDICINE, July 9th-15th 2017, Lipari (Italy). AUTHORS: Giulia Fiscon, Federica Conte, Paola Paci. TITLE: SWIM: a computational tool for network medicine. Jul 2017 LIPARI SCHOOL ON COMPUTATIONAL DRUG SCIENCE AND HIGH-PRECISION MEDICINE, July 9th-15th 2017, Lipari (Italy). [Best poster award]. AUTHORS: Federica Conte, Giulia Fiscon, Paola Paci. TITLE: Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer. May 2017 REGIONE LAZIO – Le nuove sfide della ricerca oncologica: verso una partnership tra Enti Pubblici e Industria nella regione Lazio, May 17th 2017, Rome (Italy). AUTHORS: Federica Conte*, Giulia Fiscon, Paola Paci, Pasquale Palumbo, Paola Bertolazzi. *Corrisponding author TITLE: Optimization, Models, And Algorithms For Bionformatics And Systems Biology. Jul 2016 LIPARI SCHOOL ON COMPUTATIONAL MICROBIOLOGY AND MICROBIOME-BASED MEDICINE, July 17th-24th 2016, Lipari (Italy). [Best poster award]. AUTHORS: Giulia Fiscon, Federica Conte, Teresa Colombo, Lorenzo Farina, Paola Paci. TITLE: Integrated network analysis for studying human lung squamous cell carcinoma. Jul 2016 LIPARI SCHOOL ON COMPUTATIONAL MICROBIOLOGY AND MICROBIOME-BASED MEDICINE, July 17th-24th 2016, Lipari (Italy). [Best poster award]. AUTHORS: Alessandro Bertuzzi, Federica Conte , Geltrude Mingrone, Federico Papa, Serenella Salinari and Carmela Sinisgalli. TITLE: Insulin Signaling in Insulin Resistance States and Cancer: A Modeling Analysis. Jun 2016 GNB 2016 – Gruppo Nazionale di Bioingegneria, June 20th-22nd 2016, Naples (Italy). AUTHORS: Giulia Fiscon, Federica Conte, Teresa Colombo, Lorenzo Farina, Paola Paci. TITLE: Integrated network analysis for studying human lung squamous cell carcinoma. Feb 2015 GBIOSB/LORENTZ WORKSHOP "DATA INTEGRATION IN THE LIFE SCIENCES", February 2015, Leiden (Netherlands). AUTHORS: Federica Conte, Alessandro Bertuzzi, Geltrude Mingrone, Federico Papa, Serenella Salinari and Carmela Sinisgalli. TITLE: Mathematical modeling of the insulin signaling pathway and parameter estimation from experimental data. Research Interests Bioinformatics, Computational Biology, Network Medicine, Systems Biology, Mathematical modeling and parameter estimation in Biomedicine, Optimal control theory, Biomedical Engineering. BIBLIOMETRIC INDEXES (SCOPUS) H-index 17 Number of citations 967 Number of articles 42

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