11573/1680491 - 2023 -
Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators Bufano, Marianna; Puxeddu, Michela; Nalli, Marianna; La Regina, Giuseppe; Toto, Angelo; Liberati, Francesca Romana; Paone, Alessio; Cutruzzolà, Francesca; Masci, Domiziana; Bigogno, Chiara; Dondio, Giulio; Silvestri, Romano; Gianni, Stefano; Coluccia, Antonio - 01a Articolo in rivista
rivista: BIOORGANIC CHEMISTRY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 106607- - issn: 0045-2068 - wos: WOS:001007153500001 (0) - scopus: 2-s2.0-85159597372 (0)
11573/1688401 - 2023 -
Valorisation of Side Stream Products through Green Approaches: The Rapeseed Meal Case Cairone, F.; Allevi, D.; Cesa, S.; Fabrizi, G.; Goggiamani, A.; Masci, D.; Iazzetti, A. - 01a Articolo in rivista
rivista: FOODS (Basel: MDPI) pp. 3286- - issn: 2304-8158 - wos: WOS:001062011600001 (0) - scopus: 2-s2.0-85170257810 (0)
11573/1696165 - 2023 -
Recent advances in drug discovery for Triple-Negative Breast cancer treatment Masci, Domiziana; Naro, Chiara; Puxeddu, Michela; Urbani, Andrea; Sette, Claudio; La Regina, Giuseppe; Silvestri, Romano - 01g Articolo di rassegna (Review)
rivista: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:001120971200001 (1) - scopus: 2-s2.0-85177764631 (1)
11573/1696179 - 2023 -
4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells Masci, Domiziana; Puxeddu, Michela; Di Magno, Laura; D'ambrosio, Michele; Parisi, Anastasia; Nalli, Marianna; Bai, Ruoli; Coluccia, Antonio; Sciò, Pietro; Orlando, Viviana; D'angelo, Sara; Biagioni, Stefano; Urbani, Andrea; Hamel, Ernest; Nocentini, Alessio; Filiberti, Serena; Turati, Marta; Ronca, Roberto; Kopecka, Joanna; Riganti, Chiara; Fionda, Cinzia; Bordone, Rosa; Della Rocca, Giorgia; Canettieri, Gianluca; Supuran, Claudiu T; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 14824-14842 - issn: 1520-4804 - wos: WOS:001096765200001 (1) - scopus: 2-s2.0-85176509722 (1)
11573/1684557 - 2023 -
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent Nalli, Marianna; Di Magno, Laura; Wen, Yichao; Liu, Xin; D’Ambrosio, Michele; Puxeddu, Michela; Parisi, Anastasia; Sebastiani, Jessica; Sorato, Andrea; Coluccia, Antonio; Ripa, Silvia; Di Pastena, Fiorella; Capelli, Davide; Montanari, Roberta; Masci, Domiziana; Urbani, Andrea; Naro, Chiara; Sette, Claudio; Orlando, Viviana; D’Angelo, Sara; Biagioni, Stefano; Bigogno, Chiara; Dondio, Giulio; Pastore, Arianna; Stornaiuolo, Mariano; Canettieri, Gianluca; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
rivista: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. 1087-1103 - issn: 2575-9108 - wos: WOS:001022871100001 (0) - scopus: 2-s2.0-85164931909 (0)
11573/1669754 - 2023 -
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo Sebastiani, J.; Puxeddu, M.; Nalli, M.; Bai, R.; Altieri, L.; Rovella, P.; Gaudio, E.; Trisciuoglio, D.; Spriano, F.; Lavia, P.; Fionda, C.; Masci, D.; Urbani, A.; Bigogno, C.; Dondio, G.; Hamel, E.; Bertoni, F.; Silvestri, R.; La Regina, G. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. - - issn: 1768-3254 - wos: WOS:000902003000001 (4) - scopus: 2-s2.0-85145425603 (5)
11573/1616528 - 2022 -
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000773498900001 (4) - scopus: 2-s2.0-85131007159 (4)
11573/1669809 - 2022 -
Emerging Direct Targeting β-Catenin Agents Nalli, M.; Masci, D.; Urbani, A.; La Regina, G.; Silvestri, R. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. 7735- - issn: 1420-3049 - wos: WOS:000887474600001 (3) - scopus: 2-s2.0-85142604566 (3)
11573/1664745 - 2022 -
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor Puxeddu, Michela; Wu, Jianchao; Bai, Ruoli; D’Ambrosio, Michele; Nalli, Marianna; Coluccia, Antonio; Manetto, Simone; Ciogli, Alessia; Masci, Domiziana; Urbani, Andrea; Fionda, Cinzia; Coni, Sonia; Bordone, Rosa; Canettieri, Gianluca; Bigogno, Chiara; Dondio, Giulio; Hamel, Ernest; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 15805-15818 - issn: 0022-2623 - wos: WOS:000888017600001 (12) - scopus: 2-s2.0-85142634063 (11)
11573/1436323 - 2020 -
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains Nalli, M.; Armijos Rivera, J. I.; Masci, D.; Coluccia, A.; Badia, R.; Riveira-Muñoz, E.; Brambilla, A.; Cinquina, E.; Turriziani, O.; Falasca, F.; Catalano, M.; Limatola, C.; Esté, J. A.; Maga, G.; Silvestri, R.; Crespan, E.; La Regina, G. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000600384300005 (9) - scopus: 2-s2.0-85090028457 (9)
11573/1338512 - 2019 -
Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Bufano, M.; Nalli, M.; Coluccia, A.; Orlando, V.; Canettieri, G.; Gianni, S.; Silvestri, R. - 04f Poster
congresso: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
libro: Abstract Book - ()
11573/1338507 - 2019 -
Small molecule inhibitors of kdm5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing JARID1B La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Nalli, M.; Coluccia, A.; Negri, R.; Silvestri, R. - 04f Poster
congresso: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
libro: Abstract Book - ()
11573/1348230 - 2019 -
A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution Lauder, Kate; Masci, Domiziana; Toscani, Anita; Al Mekdad, Aya; Black, Gary W.; Brown, Nicola L.; Turner, Nicholas J.; Luisi, Renzo; Castagnolo, Daniele - 01a Articolo in rivista
rivista: ORGANIC & BIOMOLECULAR CHEMISTRY (Cambridge : Royal Society of Chemistry, c2003-) pp. - - issn: 1477-0539 - wos: WOS:000490731400006 (1) - scopus: 2-s2.0-85073488621 (1)
11573/1284052 - 2019 -
Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: structure-activity relationships and mode of action studies Masci, D.; Hind, C.; Islam, M. K.; Toscani, A.; Clifford, M.; Coluccia, A.; Conforti, Irene; Touitou, M.; Memdouh, S.; Wei, X.; La Regina, G.; Silvestri, R.; Sutton, J. M.; Castagnolo, D. - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 500-514 - issn: 0223-5234 - wos: WOS:000480664100037 (19) - scopus: 2-s2.0-85067210411 (20)
11573/1316273 - 2019 -
Biocatalytic aromatization of indolines into indoles by monoamine oxidase (MAO-N) whole cells Masci, D.; Zhao, F.; Colonna, S.; Black, G.; Turner, N. J.; Castagnolo, D. - 04f Poster
congresso: 14th International Symposium on Biocatalysis and Biotransformations (BioTrans 2019) (Groningen)
libro: Biotrans 2019 Symposium - Program Book - ()
11573/1286716 - 2019 -
Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria Masci, Domiziana; Sutton, Mark; Castagnolo, Daniele - 04f Poster
congresso: 3rd International StaPa Retreat (Rome)
libro: Poster - ()
11573/1117651 - 2018 -
New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors La Regina, Giuseppe; Bai, Ruoli; Coluccia, Antonio; Naccarato, Valentina; Famiglini, Valeria; Nalli, Marianna; Masci, Domiziana; Verrico, Annalisa; Rovella, Paola; Mazzoccoli, Carmela; Da Pozzo, Eleonora; Cavallini, Chiara; Martini, Claudia; Vultaggio, Stefania; Dondio, Giulio; Varasi, Mario; Mercurio, Ciro; Hamel, Ernest; Lavia, Patrizia; Silvestri, Romano - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 283-297 - issn: 0223-5234 - wos: WOS:000435048900023 (28) - scopus: 2-s2.0-85046738606 (30)
11573/1118125 - 2018 -
Indolylarylsulfones with potent anti-HIV-1 activity Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04f Poster
congresso: 31st International Conference on Antiviral Research (Porto, Portogallo)
libro: Program and Abstracts - ()
11573/1286679 - 2018 -
Indolylarylsulfones as novel potent anti-HIV-1 agents Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04d Abstract in atti di convegno
congresso: 9th Biology and Molecular Medicine PhD School Symposium (BeMM) (Roma)
libro: Book of Abstract - ()
11573/1284150 - 2017 -
Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Badia, Roger; Esté, José A.; Crespan, Emmanuele; Maga, Giovanni - 04d Abstract in atti di convegno
congresso: 30th International Conference on Antiviral Research (Atlanta, Stati Uniti)
libro: Program and Abstracts - ()
11573/1014226 - 2017 -
Chiral indolylarylsulfone non-nucleoside reverse transcriptase inhibitors as new potent and broad spectrum anti-HIV-1 agents Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Brancale, Andrea; Badia, Roger; Riveira Muã±Oz, Eva; Estã©, Josã© A.; Crespan, Emmanuele; Brambilla, Alessandro; Maga, Giovanni; Catalano, Myriam; Limatola, Cristina; Formica, Francesca Romana; Cirilli, Roberto; Novellino, Ettore; Silvestri, Romano - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6528-6547 - issn: 0022-2623 - wos: WOS:000407656700004 (18) - scopus: 2-s2.0-85027261384 (20)
11573/1033450 - 2017 -
Inhibition of Dengue virus by novel inhibitors of RNA-dependent RNA polymerase and protease activities La Regina, Giuseppe; Famiglini, Valeria; Masci, Domiziana; Coluccia, Antonio; Lee, Jin-Ching; Hiscott, John; Silvestri, Romano - 04f Poster
congresso: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
libro: Book of Abstracts - ()
11573/1033458 - 2017 -
Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors Masci, Domiziana; La Regina, Giuseppe; Famiglini, Valeria; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04f Poster
congresso: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
libro: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()
11573/1033449 - 2017 -
Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors Passacantilli, Sara; Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Esté, José A.; Maga, Giovanni; Silvestri, Romano - 04f Poster
congresso: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
libro: Book of Abstracts - ()
11573/1025425 - 2017 -
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities Pelliccia, S.; Wub, Y. H.; Coluccia, A.; La Regina, G.; Tseng, C. K.; Famiglini, V.; Masci, D.; Hiscott, J.; Lee, J. C.; Silvestri, R. - 01a Articolo in rivista
rivista: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1091-1101 - issn: 1475-6366 - wos: WOS:000408991900004 (30) - scopus: 2-s2.0-85026861941 (32)