Cinzia Fionda

Associate professor

email: cinzia.fionda@uniroma1.it
phone: 0649255121
building: Ex-Regina Elena Palazzina B
room: 314

Personal information
Cinzia Fionda
Department of Molecular Medicine, Sapienza, University of Rome
Viale Regina Elena 291, 00161 Rome
cinzia.fionda@uniroma1.it
Education and training
1999 Degree in Biological Science, Sapienza, University of Rome.
2000 Training in Immunology, Department of Experimental Medicine and Pathology, Sapienza, University of Rome.
2005 PhD in Immunology Sapienza, University of Rome.
Working experience
2005 Scientific collaborator, Dept. Experimental Medicine, “Sapienza” University of Rome
Immunology and Immunopathology.
2006-08 Research fellow FIRC, Dept. Experimental Medicine, “Sapienza” University of Rome.
2009-11 Postdoc research fellow, Dept. Experimental Medicine, “Sapienza” University of Rome.
2012-16 Researcher Assistant Professor (RTDA), Dept. Molecular Medicine, “Sapienza”, University of Rome.
2017-2020 Researcher Assistant Professor (RTDB), Dept. Molecular Medicine, “Sapienza”, University of Rome.
2020-oggi Associate Professor Dept. Molecular Medicine, “Sapienza”, University of Rome.

Teaching experience
2006/07 Immunology Lectures and member of examination board in the course of “Immunology and Immunopathology”, Master Degree in Medicine and Surgery, Sapienza, University of Rome.
2015/16 Course of Immunology, Master Degree in Biological Sciences (6 CFU), La Tuscia, University of Viterbo.
2015-today Course of Immunology, Master Degree in Pharmacy (8 CFU), Sapienza, University of Rome.
2017-today Immunology Lectures and member of examination board in the course of “Immunology and Immunopathology”, Master Degree in Medicine and Surgery, Sapienza, University of Rome.
2017-today Faculty member of PhD course in “Innovation in Immuno-mediated and hematological disorders” Sapienza, University of Rome.
2017-today Course of Microbiology, Virological Diagnostics module, Master degree in Biomedical Laboratory Technician, Sapienza, University of Rome.
2019-today Faculty member of the Postgraduate School of Clinical Pathology and Clinical Biochemistry, Sapienza, University of Rome.
2020- today Course of Technical sciences of laboratory medicine, Master degree in Sciences of diagnostic technical health professions Sapienza, University of Rome.
Editorial experiences
2017 Guest editor for Journal of Immunology Research, Special issue: "The role of Natural killer cells in cancer: therapeutic implications".
2017 Guest editor for AIMS Allergy Immunology-Special issue: "Novel insights in NK cell receptors and their ligands in health and disease".
2017-oggi Associate editor for “Frontiers in Immunology”.
2019 Guest editor for Journal of Clinical Medicine, Special issue “Development and Function of NK cells and its Importance in Immunotherapy”

Publications
1-Cippitelli M., Fionda C., Di Bona D., Di Rosa F., Lupo A., Piccoli M., Frati L. and Santoni A. Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes. J. Immunol. 2002. February (1), 168(3), 1154-66. doi: 10.4049/jimmunol.168.3.1154.
2-Cippitelli M., Fionda C., Di Bona D., Lupo A., Piccoli M., Frati L. and Santoni A. The cyclopentenone-type prostaglandin 15-deoxy-delta12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms.J. Immunol. 2003. May 1;170(9), 4578-92. doi: 10.4049/jimmunol.170.9.4578.
3-Cippitelli M*., Fionda C.*, Di Bona D., Piccoli M., Frati L. and Santoni A. Hyperthermia enhances CD95-Ligand gene expression in T lymphocytes. J. Immunol. 2005. Jan 1;174 (1), 223-32. (*equally contributed). doi: 10.4049/jimmunol.174.1.223.
4-Di Bona D., Cippitelli M., Fionda C., Licata A., Santoni A. and Craxì A. Oxidative stress inhibits expression of IFN-induced antiviral gene expression by blocking the JAK-STAT pathway. J. Hepatol. 2006 Aug 1;45(2):271-9. Epub 2006 Mar 9. doi:10.1016/j.jhep.2006.01.037.
5-Fionda C., Nappi F., Piccoli M., Frati L., Santoni A. and Cippitelli M.15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors.J. Immunol. 2007 Apr 1;178(7):4039-50. doi: 10.4049/jimmunol.178.7.4039.
6-Fionda C., Nappi F., Piccoli M., Frati L., Santoni A. and Cippitelli M. Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes. Mol. Pharmacol. 2007. Nov3;72(5):1246-57. doi:10.1124/mol.107.038042.
7-Soriani A, Zingoni A, Cerboni C, Iannitto ML, Ricciardi MR, Di Gialleoonardo V, Cippitelli M, Fionda C, Petrucci MT, Guarini A, Foa R, Santoni A. ATM-ATR dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK susceptibility and is associated with a senescent phenotype. Blood. 2009 Apr 9;113(15):3503-11. doi: 10.1182/blood-2008-08-173914.
8-Fionda C, Soriani A, Malgarini G, Iannitto ML, Santoni A, Cippitelli M. Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation. J. Immunol. 2009 Oct 1;183(7):4385-94. doi 10.4049/jimmunol. 0901797.
9-Quinci AC., Vitale S., Parretta E., Soriani A., Iannitto ML., Cippitelli M., Fionda C., Bulfone-Paus S., Santoni A., Di Rosa F. IL-15 inhibits IL-7 Rα expression by memory phenotype CD8 T cells in the bone marrow. Eur. J. Immunol. 2012 May; 42(5): 1129-39. doi: 10.1002/eji. 2011142019.
10-Fionda C., Malgarini G., Soriani A., Zingoni A., Cecere F., Iannitto ML., Ricciardi MR., Federico V., Petrucci MT., Santoni A., Cippitelli M. Inhibition of Glycogen Synthase Kinase-3 increases NKG2D Ligand MICA expression and sensitivity to NK cell–mediated cytotoxicity in multiple myeloma cells: role of STAT3. J. Immunol. 2013. Jun 15;190 (12):6662-72. doi: 10.4049/jimmunol.1201426.

11-Soriani A, Fionda C, Ricci B, Iannitto ML, Cippitelli M, Santoni A. Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma.Oncoimmunology. 2013. Dec 1;2(12):e26663. doi.org/10.4161/onci.26663.

12-Cerboni C, Fionda C, Soriani A, Zingoni A, Doria M, Cippitelli M, Santoni A. The DNA damage response: a common pathway in the regulation of NKG2D and DNAM-1 ligand expression in normal, infected, and cancer cells. Front. Immunol. 2014. 4: (508). doi10.3389/fimmu.2013.00508.
13-Soriani A, Iannitto ML, Ricci B, Fionda C, Malgarini G, Morrone S, Peruzzi G, Ricciardi MR, Petrucci MT, Cippitelli M, Santoni A.Reactive oxygen species- and DNA damage response dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.J. Immunol. 2014. 193(2):950-60. doi: 10.4049/jimmunol.1400271.
14-Fionda C, Abruzzese MP, Zingoni A, Soriani A, Ricci B, Molfetta R, Paolini R, Santoni A, Cippitelli M. Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation. BMC Cancer. 2015. 22;15:17. doi: 10.1186/s12885-015-1023-5.
15-Zingoni A, Cecere F, Vulpis E, Fionda C, Molfetta R, Soriani A, Petrucci MT, Ricciardi MR, Fuerst D, Amendola MG, Mytilineos J, Cerboni C, Paolini R, Cippitelli M, Santoni A. Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.J. Immunol. 2015. 195(2):736-48. doi: 10.4049/jimmunol.1402643.
16- Fionda C., Soriani A., Zingoni A., Santoni A., Cippitelli M. NKG2D and DNAM-1 Ligands: molecular targets for NK cell-mediated immunotherapeutic intervention in Multiple Myeloma. Biomed Res. Int. 2015: 178698. doi: 10.1155/2015/178698.
17- Fionda C, Abruzzese MP, Zingoni A, Cecere F, Vulpis E, Peruzzi G, Soriani A, Molfetta R, Paolini R, Ricciardi MR, Petrucci MT, Santoni A, Cippitelli M. The IMiDs targets IKZF1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in Multiple Myeloma. Oncotarget 2015. 6(27): 23609-30. doi: 10.18632/oncotarget.4603.
18- Quatrini L, Molfetta R, Zitti B, Peruzzi G, Fionda C, Capuano C, Galandrini R, Cippitelli M, Santoni A, Paolini R. Ubiquitin-dependent NKG2D/DAP10 endocytosis controls signal propagation and functional responses in human Natural Killer cells. Sci Signal. 2015 Oct 27;8(400):ra108. doi: 10.1126/scisignal.aab2724.
19- Fionda C, Abruzzese MP, Santoni A, CippitelliM. Immunoregulatory and effector activities of nitric oxide and reactive nitrogen species in cancer. Curr Med Chem. 2016, 23(24), 2618-2636. doi:10.2174/0929867323666160727105101.
20- Pignoloni B*, Fionda C*, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C. (*Authors equally contributed). Distinct roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the transcriptional regulation of MICA and PVR/CD155 expression. .J. Immunol. 2016 Nov 15;197 (10):4066-4078. doi:10.4049/jimmunol.1502527.
21- Abruzzese MP, Bilotta MT, Fionda C, Zingoni A, Soriani A, Vulpis E, Borrelli C, Zitti B, Petrucci MT, Ricciardi MR, Molfetta R, Paolini R, Santoni A, Cippitelli M. Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay. J Hematol Oncol. 2016 Dec 1;9(1):134. doi: 10.1186/s13045-016-0362-2.
22-Soriani A, Borrelli C, Ricci B, Molfetta R, Zingoni A, Fionda C, Carnevale S, Abruzzese MP, Petrucci MT, Ricciardi MR, La Regina G, Di Cesare E, Lavia P, Silvestri R, Paolini R, Cippitelli M &Santoni A. p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells. Oncoimmunology 2016 Dec 2; 6(1): e1264564. doi: 10.1080/2162402X.2016.1264564.
23- Vulpis E, Cecere F, Molfetta R, Soriani A, Fionda C, Peruzzi G, Caracciolo G, Palchetti S, Masuelli L, Simonelli L, D’Oro U, Abruzzese MP, Petrucci MT, Ricciardi MT, Paolini R, Cippitelli M, Santoni A, ZingoniA. Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis. Oncoimmunology. 2017 Jan 13;6(3): e1279372. doi: 10.1080/2162402X.2017.1279372. eCollection 2017.
24- Stabile H*, Fionda C*, Gismondi A and Santoni A. Role of Distinct Natural Killer Cell Subsets in Anticancer Response. 2017. Front Immunol. 2017 Mar 16; 8:293. doi: 10.3389/fimmu.2017.00293. eCollection 2017. Review (*Authors equally contributed).
25- Stabile H, Nisti P, Peruzzi G, Fionda C, Daria P, Letizia P, Merli P, Locatelli F, Santoni A, Gismondi A. Reconstitution of multifunctional CD56lowCD16low natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation. Oncoimmunol. 2017 Aug 10;6(9): e1342024. doi: 10.1080/2162402X.2017.1342024.
26- Zitti B, Molfetta R, Fionda C, Quatrini L, Stabile H, Lecce M, de Turris V, Ricciardi MR, Petrucci MT, Cippitelli M, Gismondi A, Santoni A, Paolini R. Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells. Sci Rep. 2017 Sep 5;7(1):10445. doi:10.1038/s41598-017-10403-0.
27- Zingoni A, Fionda C, Borrelli C, Cippitelli M, Santoni A, Soriani A. Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance. Front Immunol. 2017 Sep 25; 8:1194. doi: 10.3389/fimmu.2017.01194.
28- Zingoni A, Molfetta R, Fionda C, Soriani A, Paolini R, Cippitelli M, Cerboni C, Santoni A. NKG2D and Its Ligands: "One for All, All for One". Front Immunol. 2018 Mar 12; 9:476. doi:
10.3389/fimmu.2018.00476. eCollection 2017. Review.
29- Stabile H, Fionda C, Santoni A, Gismondi A. Impact of bone marrow-derived signals on NK cell development and functional maturation. Cytokine Growth Factor Rev. 2018 Mar 27. doi: 10.1016/j.cytogfr.2018.03.008. Epub 2018 Mar 27. Review.
30- Borrelli C, Ricci B, Vulpis E, Fionda C, Ricciardi MR, Petrucci MT, Masuelli L, Peri A, Cippitelli M, Zingoni A, Santoni A, Soriani A. Drug-induced senescent multiple myeloma cells elicit NK cell proliferation by direct or exosome-mediated IL-15 trans-presentation. Cancer Immunol Res. 2018 Apr 24. doi: 10.1158/2326-6066.CIR-17-0604. Epub 2018 Apr 24.
31- Zingoni A, Vulpis E, Cecere F, Amendola MG, Fuerst D, Saribekyan T, Achour A, Sandalova T, Nardone I, Peri A, Soriani A, Fionda C, Mariggiò E, Petrucci MT, Ricciardi MR, Mytilineos J, Cippitelli M, Cerboni C, Santoni A. MICA-129 dimorphism and soluble MICA are associated with the progression of multiple myeloma. Front Immunol. 2018 May 1; 9:926. doi: 10.3389/fimmu.2018.00926. eCollection 2018.
32- Stabile H, Fionda C, Santoni A, Gismondi A. Impact of bone marrow-derived signals on NK cell development and functional maturation. Cytokine Growth Factor Rev. 2018 Aug;42:13-19. doi: 10.1016/j.cytogfr.2018.03.008. Epub 2018 Mar 27. Review.
33- Stabile H, Scarno G, Fionda C, Gismondi A, Santoni A, Gadina M, Sciumè G. JAK/STAT signaling in regulation of innate lymphoid cells: The gods before the guardians. Immunol Rev. 2018 Nov;286(1):148-159. doi: 10.1111/imr.12705. Review.
34- Fionda C, Stabile H, Molfetta R, Soriani A, Bernardini G, Zingoni A, Gismondi A, Paolini R, Cippitelli M, Santoni A. Translating the anti-myeloma activity of Natural Killer cells into clinical application. Cancer Treat Rev. 2018 Nov; 70:255-264. doi: 10.1016/j.ctrv.2018.10.005. Epub 2018 Oct 10. Review.
35- Vulpis E, Stabile H, Soriani A, Fionda C, Petrucci MT, Mariggio' E, Ricciardi MR, Cippitelli M, Gismondi A, Santoni A, Zingoni A. Key Role of the CD56lowCD16low Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells. Cancers (Basel). 2018 Nov 29;10(12). pii: E473. doi: 10.3390/cancers10120473.
36- Sciumè G, Fionda C, Stabile H, Gismondi A, Santoni A. Negative regulation of innate lymphoid cell responses in inflammation and cancer. Immunol Lett. 2019 Jan 31. pii: S0165-2478(18)30610-2. doi: 10.1016/j.imlet.2019.01.011.
37- Molfetta R, Milito ND, Zitti B, Lecce M, Fionda C, Cippitelli M, Santoni A, Paolini R.The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing. Eur J Immunol. 2019 Mar 19. doi: 10.1002/eji.201847848.
38- Abruzzese MP, Bilotta MT, Fionda C, Zingoni A, Soriani A, Petrucci MT, Ricciardi MR, Molfetta R, Paolini R, Santoni A, Cippitelli M. The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors. Cell Death Dis. 2019 Apr 11;10(4):324. doi: 10.1038/s41419-019-1562-9.
39- Bilotta MT, Abruzzese MP, Molfetta R, Scarno G, Fionda C, Soriani A, Zingoni A, Paolini R, Santoni A, Cippitelli M. Activation of Liver X Receptor upregulates the expression of the NKG2D ligands MICA and MICB in Multiple Myeloma through different molecular mechanisms. FASEB J. 2019 May 24:fj201900319R. doi: 10.1096/fj.201900319R.
40- Fionda C, Di Bona D, Kosta A, Stabile H, Santoni A, Cippitelli M. The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress. Cancers (Basel). 2019 Jun 11;11(6). pii: E810. doi: 10.3390/cancers11060810.
41- Stabile H, Nisti P, Fionda C, Pagliara D, Gaspari S, Locatelli F, Santoni A, Gismondi A. NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells. J Clin Med. 2019 Nov 7;8(11). pii: E1904. doi: 10.3390/jcm8111904.
42- Fionda C, Stabile H, Cerboni C, Soriani A, Gismondi A, Cippitelli M, Santoni A. Hitting More Birds with a Stone: Impact of TGF-β on ILC Activity in Cancer. J Clin Med. 2020 Jan 5;9(1). pii: E143. doi: 10.3390/jcm9010143. Review.
43- Molfetta R, Zitti B, Lecce M, Milito ND, Stabile H, Fionda C, Cippitelli M, Gismondi A, Santoni A, Paolini R. CD155: A Multi-Functional Molecule in Tumor Progression. Int J Mol Sci. 2020 Jan 30;21(3). pii: E922. doi: 10.3390/ijms21030922. Review.
44- Mekhloufi A, Kosta A, Stabile H, Molfetta R, Zingoni A, Soriani A, Cippitelli M, Paolini R, Gismondi A, Ricciardi MR, Petrucci MT, Masuelli L, Caracciolo G, Palchetti S, Santoni A, Fionda C. Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor. Cancers (Basel). 2020 Feb 13;12(2). pii: E440. doi: 10.3390/cancers12020440.
45- Macchia I, La Sorsa V, Ruspantini I, Sanchez M, Tirelli V, Carollo M, Fedele G, Leone P, Schiavoni G, Buccione C, Rizza P, Nisticò P, Palermo B, Morrone S, Stabile H, Rughetti A, Nuti M, Zizzari IG, Fionda C, Maggio R, Capuano C, Quintarelli C, Sinibaldi M, Agrati C, Casetti R, Rozo Gonzalez A, Iacobone F, Gismondi A, Belardelli F, Biffoni M, Urbani F. Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring. J Immunol Res. 2020 Apr 12;2020:1938704. doi: 10.1155/2020/1938704. eCollection 2020.
46- Cippitelli M, Stabile H, Kosta A, Petillo S, Gismondi A, Santoni A, Fionda C. Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them. Int J Mol Sci. 2021 Jan 22;22(3):1103. doi: 10.3390/ijms22031103.
47-Fionda C, Stabile H, Molfetta R, Kosta A, Peruzzi G, Ruggeri S, Zingoni A, Capuano C, Soriani A, Paolini R, Gismondi A, Cippitelli M, Santoni A. Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation. Eur J Immunol. 2021 Nov;51(11):2607-2617. doi: 10.1002/eji.202149269. Epub 2021 Sep 18.
48-Petillo S, Capuano C, Molfetta R, Fionda C, Mekhloufi A, Pighi C, Antonangeli F, Zingoni A, Soriani A, Petrucci MT, Galandrini R, Paolini R, Santoni A, Cippitelli M. Immunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition. Cell Death Dis. 2021 Sep 4;12(9):836. doi: 10.1038/s41419-021-04104-w.
49Grimaldi A, Pietropaolo G, Stabile H, Kosta A, Capuano C, Gismondi A, Santoni A, Sciumè G, Fionda C. The Regulatory Activity of Noncoding RNAs in ILCs. Cells. 2021 Oct 14;10(10):2742. doi: 10.3390/cells10102742.
50-Vulpis E, Loconte L, Peri A, Molfetta R, Caracciolo G, Masuelli L, Tomaipitinca L, Peruzzi G, Petillo S, Petrucci MT, Fazio F, Simonelli L, Fionda C, Soriani A, Cerboni C, Cippitelli M, Paolini R, Bernardini G, Palmieri G, Santoni A, Zingoni A. Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle-associated MICA: Dual role in cancer immunosurveillance. J Extracell Vesicles. 2022 Jan;11(1): e12176. doi: 10.1002/jev2.12176.
51- Capuano C, Pighi C, Battella S, Pulcinelli F, Santoro C, Ferretti A, Turriziani O, De Federicis D, Fionda C, Sciumè G, Galandrini R, Palmieri G. (Auto) Antibody Responses Shape Memory NK Cell Pool Size and Composition. Biomedicines. 2022 Mar 8;10(3):625. doi: 10.3390/biomedicines10030625.
52-Kosta A, Mekhloufi A, Lucantonio L, Zingoni A, Soriani A, Cippitelli M, Gismondi A, Fazio F, Petrucci MT, Santoni A, Stabile H, Fionda C. GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells. Front Immunol. 2022 Jul 28;13:942640. doi: 10.3389/fimmu.2022.942640. eCollection 2022.
53-Fionda C, Scarno G, Stabile H, Molfetta R, Di Censo C, Gismondi A, Paolini R, Sozzani S, Santoni A, Sciumè G. NK Cells and Other Cytotoxic Innate Lymphocytes in Colorectal Cancer Progression and Metastasis. Int J Mol Sci. 2022 Jul 16;23(14):7859. doi: 10.3390/ijms23147859.
54- Puxeddu M, Wu J, Bai R, D'Ambrosio M, Nalli M, Coluccia A, Manetto S, Ciogli A, Masci D, Urbani A, Fionda C, Coni S, Bordone R, Canettieri G, Bigogno C, Dondio G, Hamel E, Liu T, Silvestri R, La Regina G. Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor. J Med Chem. 2022 Dec 8;65(23):15805-15818. doi: 10.1021/acs.jmedchem.2c01457. Epub 2022 Nov 17.
55- Fionda C, Ruggeri S, Sciumè G, Laffranchi M, Quinti I, Milito C, Palange P, Menichini I, Sozzani S, Frati L, Gismondi A, Santoni A, Stabile H. Age-dependent NK cell dysfunctions in severe COVID-19 patients. Front Immunol. 2022 Nov 17;13:1039120. doi: 10.3389/fimmu.2022.1039120. eCollection 2022.
56- Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5.
57- Cippitelli M, Stabile H, Kosta A, Petillo S, Lucantonio L, Gismondi A, Santoni A, Fionda C. Role of NF-κB Signaling in the Interplay between Multiple Myeloma and Mesenchymal Stromal Cells. Int. J. Mol. Sci. 2023, 24, 1823. https://doi.org/10.3390/ijms24031823.










Research products

11573/1709853 - 2024 - CD38 restrains the activity of extracellular cGAMP in a model of multiple myeloma
Cuollo, Lorenzo; Di Cristofano, Samuele; Sandomenico, Annamaria; Iaccarino, Emanuela; Oliver, Angela; Zingoni, Alessandra; Cippitelli, Marco; Fionda, Cinzia; Petillo, Sara; Kosta, Andrea; Tassinari, Valentina; Petrucci, Maria Teresa; Fazio, Francesca; Menotti, Ruvo; Santoni, Angela; Raimondo, Domenico; Soriani, Alessandra - 01a Articolo in rivista
paper: ISCIENCE ([Cambridge MA] : Cell Press Elsevier Inc.) pp. - - issn: 2589-0042 - wos: WOS:001238506200001 (1) - scopus: 2-s2.0-85192203827 (1)

11573/1712097 - 2024 - Analysis of infiltrating MC subsets in Colorectal cancer by single-cell RNA-sequencing.
Putro, Erisa; Carnevale, Alessia; Marangio, Caterina; Peruzzi, Giovanna; Fionda, Cinzia; Stabile, Helena; Pietropaolo, Giuseppe; Sciumè, Giuseppe; Gismondi, Angela; Molfetta, Rosa; Fulci, Valerio; Paolini, Rossella - 04d Abstract in atti di convegno
conference: ECI 2024 (Dublin, Ireland)
book: ECI 2024 - ()

11573/1669090 - 2023 - Role of NF-κB Signaling in the Interplay between Multiple Myeloma and Mesenchymal Stromal Cells
Cippitelli, Marco; Stabile, Maria Helena; Kosta, Andrea; Petillo, Sara; Lucantonio, Lorenzo; Gismondi, Angela; Santoni, Angela; Fionda, Cinzia - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000932958300001 (10) - scopus: 2-s2.0-85148012728 (9)

11573/1696179 - 2023 - 4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells
Masci, Domiziana; Puxeddu, Michela; Di Magno, Laura; D'ambrosio, Michele; Parisi, Anastasia; Nalli, Marianna; Bai, Ruoli; Coluccia, Antonio; Sciò, Pietro; Orlando, Viviana; D'angelo, Sara; Biagioni, Stefano; Urbani, Andrea; Hamel, Ernest; Nocentini, Alessio; Filiberti, Serena; Turati, Marta; Ronca, Roberto; Kopecka, Joanna; Riganti, Chiara; Fionda, Cinzia; Bordone, Rosa; Della Rocca, Giorgia; Canettieri, Gianluca; Supuran, Claudiu T; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 14824-14842 - issn: 1520-4804 - wos: WOS:001096765200001 (2) - scopus: 2-s2.0-85176509722 (3)

11573/1685597 - 2023 - NEDD8-activating enzyme inhibition potentiates the anti-myeloma activity of natural killer cells
Petillo, S.; Sproviero, E.; Loconte, L.; Cuollo, L.; Zingoni, A.; Molfetta, R.; Fionda, C.; Soriani, A.; Cerboni, C.; Petrucci, M. T.; Fazio, F.; Paolini, R.; Santoni, A.; Cippitelli, M. - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 438- - issn: 2041-4889 - wos: WOS:001031302800001 (4) - scopus: 2-s2.0-85165040036 (4)

11573/1690639 - 2023 - Nitric Oxide Prevents Glioblastoma Stem Cells’ Expansion and Induces Temozolomide Sensitization
Salvatori, L.; Malatesta, S.; Illi, B.; Somma, M. P.; Fionda, C.; Stabile, H.; Fontanella, R. A.; Gaetano, C. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-23 - issn: 1422-0067 - wos: WOS:001036199400001 (0) - scopus: 2-s2.0-85166241447 (2)

11573/1692972 - 2023 - Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation
Scarno, Gianluca; Mazej, Julija; Laffranchi, Mattia; Di Censo, Chiara; Mattiola, Irene; Candelotti, Arianna M; Pietropaolo, Giuseppe; Stabile, Helena; Fionda, Cinzia; Peruzzi, Giovanna; Brooks, Stephen R; Tsai, Wanxia Li; Mikami, Yohei; Bernardini, Giovanni; Gismondi, Angela; Sozzani, Silvano; Di Santo, James P; Vosshenrich, Christian A J; Diefenbach, Andreas; Gadina, Massimo; Santoni, Angela; Sciume, Giuseppe - 01a Articolo in rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. - - issn: 0027-8424 - wos: WOS:001230735600004 (1) - scopus: 2-s2.0-85172813212 (2)

11573/1669754 - 2023 - RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo
Sebastiani, J.; Puxeddu, M.; Nalli, M.; Bai, R.; Altieri, L.; Rovella, P.; Gaudio, E.; Trisciuoglio, D.; Spriano, F.; Lavia, P.; Fionda, C.; Masci, D.; Urbani, A.; Bigogno, C.; Dondio, G.; Hamel, E.; Bertoni, F.; Silvestri, R.; La Regina, G. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. - - issn: 1768-3254 - wos: WOS:000902003000001 (7) - scopus: 2-s2.0-85145425603 (7)

11573/1678468 - 2023 - Doxorubicin–Mediated miR–433 Expression on Exosomes Promotes Bystander Senescence in Multiple Myeloma Cells in a DDR–Independent Manner
Vulpis, Elisabetta; Cuollo, Lorenzo; Borrelli, Cristiana; Antonangeli, Fabrizio; Masuelli, Laura; Cippitelli, Marco; Fionda, Cinzia; Caracciolo, Giulio; Petrucci, Maria Teresa; Santoni, Angela; Zingoni, Alessandra; Soriani, Alessandra - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 6862- - issn: 1422-0067 - wos: WOS:000970073600001 (3) - scopus: 2-s2.0-85152709164 (4)

11573/1683019 - 2023 - Cross-Dressing of Multiple Myeloma Cells Mediated by Extracellular Vesicles Conveying MIC and ULBP Ligands Promotes NK Cell Killing
Vulpis, Elisabetta; Loconte, Luisa; Cassone, Chiara; Antonangeli, Fabrizio; Caracciolo, Giulio; Masuelli, Laura; Fazio, Francesca; Petrucci, Maria Teresa; Fionda, Cinzia; Soriani, Alessandra; Cerboni, Cristina; Cippitelli, Marco; Santoni, Angela; Zingoni, Alessandra - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001004972000001 (2) - scopus: 2-s2.0-85161586954 (2)

11573/1625384 - 2022 - (Auto)Antibody Responses Shape Memory NK Cell Pool Size and Composition
Capuano, C.; Pighi, C.; Battella, S.; Pulcinelli, F.; Santoro, C.; Ferretti, A.; Turriziani, O.; De Federicis, D.; Fionda, C.; Sciume, G.; Galandrini, R.; Palmieri, G. - 01a Articolo in rivista
paper: BIOMEDICINES (Basel: MDPI) pp. 625- - issn: 2227-9059 - wos: WOS:000775800700001 (1) - scopus: 2-s2.0-85126562052 (1)

11573/1661964 - 2022 - Age-dependent NK cell dysfunctions in severe COVID-19 patients
Fionda, Cinzia; Ruggeri, Silvia; Sciume', Giuseppe; Laffranchi, Mattia; Quinti, Isabella; Milito, Cinzia; Palange, Paolo; Menichini, Ilaria; Sozzani, Silvano; Frati, Luigi; Gismondi, Angela; Santoni, Angela; Stabile, Maria Helena - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-19 - issn: 1664-3224 - wos: WOS:000892950000001 (6) - scopus: 2-s2.0-85143231775 (8)

11573/1655262 - 2022 - NK Cells and Other Cytotoxic Innate Lymphocytes in Colorectal Cancer Progression and Metastasis
Fionda, Cinzia; Scarno, Gianluca; Stabile, Maria Helena; Molfetta, Rosa; Di Censo, Chiara; Gismondi, Angela; Paolini, Rossella; Sozzani, Silvano; Santoni, Angela; Sciume', Giuseppe - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 7859- - issn: 1422-0067 - wos: WOS:000833151000001 (12) - scopus: 2-s2.0-85137190157 (14)

11573/1654089 - 2022 - GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells
Kosta, Andrea; Mekhloufi, Abdelilah; Lucantonio, Lorenzo; Zingoni, Alessandra; Soriani, Alessandra; Cippitelli, Marco; Gismondi, Angela; Fazio, Francesca; Petrucci, Maria Teresa; Santoni, Angela; Stabile, Maria Helena; Fionda, Cinzia - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000879237800001 (2) - scopus: 2-s2.0-85136836715 (2)

11573/1664745 - 2022 - Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
Puxeddu, Michela; Wu, Jianchao; Bai, Ruoli; D’Ambrosio, Michele; Nalli, Marianna; Coluccia, Antonio; Manetto, Simone; Ciogli, Alessia; Masci, Domiziana; Urbani, Andrea; Fionda, Cinzia; Coni, Sonia; Bordone, Rosa; Canettieri, Gianluca; Bigogno, Chiara; Dondio, Giulio; Hamel, Ernest; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 15805-15818 - issn: 0022-2623 - wos: WOS:000888017600001 (14) - scopus: 2-s2.0-85142634063 (14)

11573/1602470 - 2022 - Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle-associated MICA. Dual role in cancer immunosurveillance
Vulpis, Elisabetta; Loconte, Luisa; Peri, Agnese; Molfetta, Rosa; Caracciolo, Giulio; Masuelli, Laura; Tomaipitinca, Luana; Peruzzi, Giovanna; Petillo, Sara; Petrucci, Maria Teresa; Fazio, Francesca; Simonelli, Lucilla; Fionda, Cinzia; Soriani, Alessandra; Cerboni, Cristina; Cippitelli, Marco; Paolini, Rossella; Bernardini, Giovanni; Palmieri, Gabriella; Santoni, Angela; Zingoni, Alessandra - 01a Articolo in rivista
paper: JOURNAL OF EXTRACELLULAR VESICLES (Järfälla : Co-Action Publishing, 2012-) pp. 1-22 - issn: 2001-3078 - wos: WOS:000736851700001 (29) - scopus: 2-s2.0-85123037207 (30)

11573/1496106 - 2021 - Role of aiolos and ikaros in the antitumor and immunomodulatory activity of imids in multiple myeloma: better to lose than to find them
Cippitelli, M.; Stabile, H.; Kosta, A.; Petillo, S.; Gismondi, A.; Santoni, A.; Fionda, C. - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000615301200001 (21) - scopus: 2-s2.0-85099698073 (24)

11573/1569443 - 2021 - Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation
Fionda, Cinzia; Stabile, Maria Helena; Molfetta, Rosa; Kosta, Andrea; Peruzzi, Giovanna; Ruggeri, Silvia; Zingoni, Alessandra; Capuano, Cristina; Soriani, Alessandra; Paolini, Rossella; Gismondi, Angela; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF IMMUNOLOGY (Weinheim : Wiley-VCH-Verl.) pp. - - issn: 1521-4141 - wos: WOS:000696906500001 (9) - scopus: 2-s2.0-85114996665 (9)

11573/1583306 - 2021 - The regulatory activity of noncoding RNAs in ILCs
Grimaldi, A.; Pietropaolo, G.; Stabile, H.; Kosta, A.; Capuano, C.; Gismondi, A.; Santoni, A.; Sciume', G.; Fionda, C. - 01g Articolo di rassegna (Review)
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000713993900001 (6) - scopus: 2-s2.0-85117047944 (7)

11573/1568857 - 2021 - Immunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition
Petillo, S.; Capuano, C.; Molfetta, R.; Fionda, C.; Mekhloufi, A.; Pighi, C.; Antonangeli, F.; Zingoni, A.; Soriani, A.; Petrucci, M. T.; Galandrini, R.; Paolini, R.; Santoni, A.; Cippitelli, M. - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000693034400003 (7) - scopus: 2-s2.0-85114613727 (9)

11573/1359055 - 2020 - Hitting more birds with a stone: impact of TGF-β on ILC activity in cancer
Fionda, Cinzia; Stabile, Helena; Cerboni, Cristina; Soriani, Alessandra; Gismondi, Angela; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF CLINICAL MEDICINE (MDPI Publishing, Basel, Switzerland) pp. - - issn: 2077-0383 - wos: WOS:000515388400143 (19) - scopus: 2-s2.0-85080052266 (19)

11573/1386510 - 2020 - Multicentre harmonisation of a six-colour flow cytometry panel for naïve/memory T cell immunomonitoring
Macchia, Iole; La Sorsa, Valentina; Ruspantini, Irene; Sanchez, Massimo; Tirelli, Valentina; Carollo, Maria; Fedele, Giorgio; Leone, Pasqualina; Schiavoni, Giovanna; Buccione, Carla; Rizza, Paola; Nisticò, Paola; Palermo, Belinda; Morrone, Stefania; Stabile, Helena; Rughetti, Aurelia; Nuti, Marianna; Zizzari, Ilaria Grazia; Fionda, Cinzia; Maggio, Roberta; Capuano, Cristina; Quintarelli, Concetta; Sinibaldi, Matilde; Agrati, Chiara; Casetti, Rita; Rozo Gonzalez, Andrea; Iacobone, Floriana; Gismondi, Angela; Belardelli, Filippo; Biffoni, Mauro; Urbani, Francesca - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY RESEARCH (Cairo : Hindawi Publishing Corporation) pp. 1-15 - issn: 2314-8861 - wos: WOS:000524295000001 (9) - scopus: 2-s2.0-85083702092 (9)

11573/1368093 - 2020 - Bone marrow stromal cell-derived IL-8 upregulates PVR expression on multiple myeloma cells via NF-kB transcription factor
Mekhloufi, A; Kosta, A; Stabile, H; Molfetta, R; Zingoni, A; Soriani, A; Cippitelli, M; Paolini, R; Gismondi, A; Ricciardi, Maria Rosaria; Petrucci, Maria Teresa; Masuelli, L; Caracciolo, G; Palchetti, S; Santoni, A; Fionda, C. - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. 1-22 - issn: 2072-6694 - wos: WOS:000522477300186 (23) - scopus: 2-s2.0-85079694562 (24)

11573/1363453 - 2020 - CD155: a multi-functional molecule in tumor progression
Molfetta, R.; Zitti, B.; Lecce, M.; Milito, Nadia Domenica; Stabile, H.; Fionda, C.; Cippitelli, M.; Gismondi, A.; Santoni, A.; Paolini, R. - 01g Articolo di rassegna (Review)
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000522551604019 (50) - scopus: 2-s2.0-85079008310 (63)

11573/1264340 - 2019 - The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in multiple myeloma. modulation by bromodomain and Extra-Terminal (BET) protein inhibitors
Abruzzese, Maria Pia; Bilotta, Maria Teresa; Fionda, Cinzia; Zingoni, Alessandra; Soriani, Alessandra; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Molfetta, Rosa; Paolini, Rossella; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000468660000005 (13) - scopus: 2-s2.0-85064251274 (14)

11573/1274659 - 2019 - Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms
Bilotta, Maria Teresa; Abruzzese, Maria Pia; Molfetta, Rosa; Scarno, Gianluca; Fionda, Cinzia; Zingoni, Alessandra; Soriani, Alessandra; Garofalo, Tina; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Paolini, Rossella; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 1-6 - issn: 0892-6638 - wos: WOS:000478832900061 (18) - scopus: 2-s2.0-85070781545 (19)

11573/1290872 - 2019 - The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress
Fionda, Cinzia; Di Bona, Danilo; Kosta, Andrea; Stabile, Helena; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000475351200074 (8) - scopus: 2-s2.0-85068670569 (9)

11573/1249876 - 2019 - The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing.
Molfetta, Rosa; Milito, Nadia D.; Zitti, Beatrice; Lecce, Mario; Fionda, Cinzia; Cippitelli, Marco; Santoni, Angela; Paolini, Rossella - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF IMMUNOLOGY (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 873-883 - issn: 0014-2980 - wos: WOS:000470912000006 (22) - scopus: 2-s2.0-85063471276 (24)

11573/1244732 - 2019 - Negative regulation of innate lymphoid cell responses in inflammation and cancer
Sciumè, Giuseppe; Fionda, Cinzia; Stabile, Helena; Gismondi, Angela; Santoni, Angela - 01a Articolo in rivista
paper: IMMUNOLOGY LETTERS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0165-2478 - wos: WOS:000498338300005 (9) - scopus: 2-s2.0-85061346622 (10)

11573/1359057 - 2019 - NK cell reconstitution in paediatric leukemic patients after T-cell-depleted HLA-haploidentical haematopoietic stem cell transplantation followed by the reinfusion of iCasp9-modified donor T cells
Stabile, Helena; Nisti, Paolo; Fionda, Cinzia; Pagliara, Daria; Gaspari, Stefania; Locatelli, Franco; Santoni, Angela; Gismondi, Angela. - 01a Articolo in rivista
paper: JOURNAL OF CLINICAL MEDICINE (MDPI Publishing, Basel, Switzerland) pp. - - issn: 2077-0383 - wos: WOS:000502294400147 (3) - scopus: 2-s2.0-85089406787 (3)

11573/1109857 - 2018 - Drug-induced senescent Multiple Myeloma cells elicit NK cell proliferation by direct or exosome-mediated IL-15 trans-presentation
Borrelli, Cristiana; Ricci, Biancamaria; Vulpis, Elisabetta; Fionda, Cinzia; Ricciardi, Maria Rosaria; Petrucci, Maria Teresa; Masuelli, Laura; Peri, Agnese; Cippitelli, Marco; Zingoni, Alessandra; Santoni, Angela; Soriani, Alessandra - 01a Articolo in rivista
paper: CANCER IMMUNOLOGY RESEARCH (American Association for Cancer Research, Inc. (AACR), 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404; Phone: (215) 440-9300 or Toll Free: (866) 423-3965; Fax: (215) 446-7289; E-mail: cancerimmunolres@aacr.org.) pp. canimm.0604.2017- - issn: 2326-6066 - wos: WOS:000437212800011 (61) - scopus: 2-s2.0-85049790279 (65)

11573/1176569 - 2018 - Translating the anti-myeloma activity of Natural Killer cells into clinical application
Fionda, C; Stabile, H; Molfetta, R; Soriani, A; Bernardini, G; Zingoni, A; Gismondi, A; Paolini, R; Cippitelli, M; Santoni, A. - 01g Articolo di rassegna (Review)
paper: CANCER TREATMENT REVIEWS (-Attuale:W B SAUNDERS CO LTD, 32 JAMESTOWN RD, LONDON, ENGLAND, NW1 7BY -Harcourt Publishers Limited:Foots Cray High Street, Sidcup Kent DA14 5HP United Kingdom:011 44 20 83085700, EMAIL: journals@harcourt.com, INTERNET: http://www.harcourt-international.com, Fax: 011 44 20 83085876) pp. 255-264 - issn: 0305-7372 - wos: WOS:000452345300027 (29) - scopus: 2-s2.0-85054654749 (29)

11573/1094145 - 2018 - Impact of bone marrow-derived signals on NK cell development and functional maturation
Stabile, Helena; Fionda, Cinzia; Santoni, Angela; Gismondi, Angela. - 01a Articolo in rivista
paper: CYTOKINE & GROWTH FACTOR REVIEWS (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 13-19 - issn: 1359-6101 - wos: WOS:000444604100003 (11) - scopus: 2-s2.0-85044772323 (14)

11573/1191152 - 2018 - JAK/STAT signaling in regulation of innate lymphoid cells: The gods before the guardians
Stabile, Helena; Scarno, Gianluca; Fionda, Cinzia; Gismondi, Angela; Santoni, Angela; Gadina, Massimo; Sciumè, Giuseppe - 01a Articolo in rivista
paper: IMMUNOLOGICAL REVIEWS (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 148-159 - issn: 0105-2896 - wos: WOS:000446561100011 (46) - scopus: 2-s2.0-85054384463 (49)

11573/1203217 - 2018 - Key role of the CD56lowCD16low Natural Killer cell subset in the recognition and killing of Multiple Myeloma cells
Vulpis, Elisabetta; Stabile, Maria Helena; Soriani, Alessandra; Fionda, Cinzia; Petrucci, Maria Teresa; Mariggio', Elena; Ricciardi, Maria Rosaria; Cippitelli, Marco; Gismondi, Angela; Santoni, Angela; Zingoni, Alessandra - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000455199200011 (26) - scopus: 2-s2.0-85058437212 (28)

11573/1094093 - 2018 - NKG2D and its ligands: one for all, all for one
Zingoni, Alessandra; Molfetta, Rosa; Fionda, Cinzia; Soriani, Alessandra; Paolini, Rossella; Cippitelli, Marco; Cerboni, Cristina; Santoni, Angela - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000427177100001 (158) - scopus: 2-s2.0-85043468645 (171)

11573/1109275 - 2018 - MICA-129 dimorphism and soluble MICA are associated with the progression of multiple myeloma
Zingoni, Alessandra; Vulpis, Elisabetta; Cecere, Francesca; Giulia Amendola, Maria; Fuerst, Daniel; Saribekyan, Taron; Achour, Adnane; Sandalova, Tatyana; Nardone, Ilaria; Peri, Agnese; Soriani, Alessandra; Fionda, Cinzia; Mariggio', Elena; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Mylitineous, Joannis; Cippitelli, Marco; Cerboni, Cristina; Santoni, Angela - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000431192300001 (36) - scopus: 2-s2.0-85046275915 (39)

11573/902826 - 2017 - p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells
Soriani, Alessandra; Borrelli, Cristiana; Ricci, Biancamaria; Molfetta, Rosa; Zingoni, Alessandra; Fionda, Cinzia; Carnevale, Silvia; Abruzzese, Maria Pia; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; La Regina, Giuseppe; Cesare, Erica Di; Lavia, Patrizia; Silvestri, Romano; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. e1264564-e1264564 - issn: 2162-402X - wos: WOS:000397069400020 (30) - scopus: 2-s2.0-85015270684 (31)

11573/952098 - 2017 - Role of distinct natural killer cell subsets in anticancer response
Stabile, Helena°; Fionda, Cinzia°; Gismondi, Angela; Santoni, Angela; °Stabile H And Fionda, C Equally Contributed - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-3224 - wos: WOS:000396350400001 (104) - scopus: 2-s2.0-85017195553 (114)

11573/1019062 - 2017 - Reconstitution of multifunctional CD56(low)CD16(low) natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation
Stabile, Maria Helena; Nisti, Paolo; Peruzzi, Giovanna; Fionda, Cinzia; Daria, Pagliara; Letizia, Pomonia Brescia; Pietro, Merli; Locatelli, Franco; Santoni, Angela; Gismondi, Angela - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. - - issn: 2162-402X - wos: WOS:000410856100020 (13) - scopus: 2-s2.0-85027344121 (19)

11573/935954 - 2017 - Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis
Vulpis, Elisabetta; Cecere, Francesca; Molfetta, Rosa; Soriani, Alessandra; Fionda, Cinzia; Peruzzi, Giovanna; Caracciolo, Giulio; Palchetti, Sara; Masuelli, Laura; Simonelli, Lucilla; D'oro, Ugo; Abruzzese, Maria Pia; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela; Zingoni, Alessandra - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. - - issn: 2162-402X - wos: WOS:000397988500010 (100) - scopus: 2-s2.0-85014499860 (103)

11573/1010694 - 2017 - Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance.
Zingoni, Alessandra; Fionda, Cinzia; Borrelli, Cristiana; Cippitelli, Marco; Santoni, Angela; Soriani, Alessandra - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. 1-10 - issn: 1664-3224 - wos: WOS:000411601400001 (94) - scopus: 2-s2.0-85029801729 (101)

11573/1003837 - 2017 - Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells
Zitti, B°; Molfetta, R°; Fionda, C; Quatrini, L; Stabile, H; Lecce, M; De Turris, V; Ricciardi, Mr; Petrucci, Mt; Cippitelli, M; Gismondi, A; Santoni, A; Paolini, R; °These Authors Contributed Equally To The, Work - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 10445- - issn: 2045-2322 - wos: WOS:000409309300033 (29) - scopus: 2-s2.0-85028913165 (29)

11573/903811 - 2016 - Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells. role of cMYC-IRF4-miR-125b interplay
Abruzzese, Maria Pia; Bilotta, Maria Teresa; Fionda, Cinzia; Zingoni, Alessandra; Soriani, Alessandra; Vulpis, Elisabetta; Borrelli, Cristiana; Zitti, Beatrice; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Molfetta, Rosa; Paolini, Rossella; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: JOURNAL OF HEMATOLOGY & ONCOLOGY (London : BioMed Central) pp. 1-19 - issn: 1756-8722 - wos: WOS:000389305200001 (70) - scopus: 2-s2.0-85001090549 (81)

11573/884550 - 2016 - Immunoregulatory and effector activities of nitric oxide and reactive nitrogen species in cancer
Fionda, Cinzia; Abruzzese, Maria Pia; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: CURRENT MEDICINAL CHEMISTRY (Hilversum: Bentham Science Publishers) pp. 2618-2636 - issn: 1875-533X - wos: WOS:000382265400005 (40) - scopus: 2-s2.0-84989187512 (41)

11573/907753 - 2016 - Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression
Pignoloni, Benedetta; Fionda, Cinzia; Dell’Oste, Valentina; Luganini, Anna; Cippitelli, Marco; Zingoni, Alessandra; Landolfo, Santo; Gribaudo, Giorgio; Santoni, Angela; Cerboni, Cristina; Fionda C., Equally Contributed - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 4066-4078 - issn: 0022-1767 - wos: WOS:000389634600030 (23) - scopus: 2-s2.0-84994415884 (24)

11573/952095 - 2016 - Targeting NKG2D and NKp30 ligands shedding to improve NK cell–based immunotherapy
Zingoni, Alessandra; Vulpis, Elisabetta; Nardone, Ilaria; Soriani, Alessandra; Fionda, Cinzia; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: CRITICAL REVIEWS IN IMMUNOLOGY (Begell House Incorporated:170 Birch Hollow:Richmondville, NY 12149:(212)725-1999, EMAIL: susan@begellhouse.com, INTERNET: http://www.begellhouse.com, Fax: (212)213-8368) pp. 445-459 - issn: 1040-8401 - wos: WOS:000408490100001 (24) - scopus: 2-s2.0-85029509079 (24)

11573/791338 - 2015 - The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma
Fionda, Cinzia; Abruzzese, Maria Pia; Zingoni, Alessandra; Cecere, Francesca; Vulpis, Elisabetta; Peruzzi, Giovanna; Soriani, Alessandra; Molfetta, Rosa; Paolini, Rossella; Ricciardi, Maria Rosaria; Petrucci, Maria Teresa; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 23609-23630 - issn: 1949-2553 - wos: WOS:000363157700043 (72) - scopus: 2-s2.0-84943409539 (73)

11573/870926 - 2015 - Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation
Fionda, Cinzia; Abruzzese, Maria Pia; Zingoni, Alessandra; Soriani, Alessandra; Ricci, Biancamaria; Molfetta, Rosa; Paolini, Rossella; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: BMC CANCER (London: BioMed Central, [2001]-) pp. 1-14 - issn: 1471-2407 - wos: WOS:000348813000002 (50) - scopus: 2-s2.0-84931262988 (52)

11573/786936 - 2015 - NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma
Fionda, Cinzia; Soriani, Alessandra; Zingoni, Alessandra; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: BIOMED RESEARCH INTERNATIONAL (London: Hindawi, [2001]-) pp. 1-9 - issn: 2314-6141 - wos: WOS:000357190200001 (59) - scopus: 2-s2.0-84934300385 (59)

11573/831022 - 2015 - Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells
Quatrini, Linda; Molfetta, Rosa; Zitti, Beatrice; Peruzzi, Giovanna; Fionda, Cinzia; Capuano, Cristina; Galandrini, Ricciarda; Cippitelli, Marco; Santoni, Angela; Paolini, Rossella - 01a Articolo in rivista
paper: SCIENCE SIGNALING () pp. - - issn: 1937-9145 - wos: WOS:000365865800005 (46) - scopus: 2-s2.0-84945551002 (48)

11573/795922 - 2015 - Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells
Zingoni, Alessandra; Cecere, Francesca; Vulpis, Elisabetta; Fionda, Cinzia; Molfetta, Rosa; Soriani, Alessandra; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; Fuerst, Daniel; Amendola, Maria Giulia; Mytilineos, Joannis; Cerboni, Cristina; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 736-748 - issn: 0022-1767 - wos: WOS:000358066800033 (82) - scopus: 2-s2.0-84936791354 (87)

11573/541538 - 2014 - The DNA damage response: a common pathway in the regulation of NKG2D and DNAM-1 ligand expression in normal, infected, and cancer cells
Cerboni, Cristina; Fionda, Cinzia; Soriani, Alessandra; Zingoni, Alessandra; Margherita, Doria; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: FRONTIERS IN IMMUNOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. art. 508-1-art. 508-7 - issn: 1664-3224 - wos: WOS:000354031300001 (105) - scopus: 2-s2.0-84987776130 (108)

11573/578579 - 2014 - Reactive Oxygen Species- and DNA Damage Response-Dependent NK Cell Activating Ligand Upregulation Occurs at Transcriptional Levels and Requires the Transcriptional Factor E2F1.
Soriani, Alessandra; Maria Luisa, Iannitto; Ricci, Biancamaria; Fionda, Cinzia; Giulia, Malgarini; Morrone, Stefania; Peruzzi, Giovanna; Ricciardi, Maria Rosaria; Maria Teresa, Petrucci; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 950-960 - issn: 0022-1767 - wos: WOS:000338958300051 (77) - scopus: 2-s2.0-84904265813 (80)

11573/516920 - 2013 - Inhibition of Glycogen Synthase Kinase-3 Increases NKG2D Ligand MICA Expression and Sensitivity to NK Cell-Mediated Cytotoxicity in Multiple Myeloma Cells: Role of STAT3
Fionda, Cinzia; Malgarini, Giulia; Soriani, Alessandra; Zingoni, Alessandra; Cecere, Francesca; Iannitto, Maria Luisa; Ricciardi, Maria Rosaria; V., Federico; Petrucci, Maria Teresa; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 6662-6672 - issn: 0022-1767 - wos: WOS:000320373700079 (61) - scopus: 2-s2.0-84879115465 (65)

11573/541540 - 2013 - Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma
Soriani, Alessandra; Fionda, Cinzia; Ricci, Biancamaria; Maria Luisa, Iannitto; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY (Austin, TX : Landes Bioscience) pp. e26663-1-e26663-3 - issn: 2162-4011 - wos: WOS:000330425100016 (39) - scopus: 2-s2.0-84896692416 (39)

11573/445266 - 2012 - IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.
Angela C., Quinci; Sara, Vitale; Elisabetta, Parretta; Soriani, Alessandra; Iannitto, Maria Luisa; Cippitelli, Marco; Fionda, Cinzia; Silvia Bulfone, Paus; Santoni, Angela; Francesca Di, Rosa - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF IMMUNOLOGY (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 1129-1139 - issn: 0014-2980 - wos: WOS:000303317700010 (21) - scopus: 2-s2.0-84860335345 (21)

11573/358675 - 2009 - Heat Shock Protein-90 Inhibitors Increase MHC Class I-Related Chain A and B Ligand Expression on Multiple Myeloma Cells and Their Ability to Trigger NK Cell Degranulation
Fionda, Cinzia; Soriani, Alessandra; Malgarini, Giulia; Iannitto, Maria Luisa; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 4385-4394 - issn: 0022-1767 - wos: WOS:000270522500031 (73) - scopus: 2-s2.0-70449717531 (78)

11573/363784 - 2009 - ATM-ATR dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK cell susceptibility and is associated with a senescent phenotype
Soriani, Alessandra; Zingoni, Alessandra; Cerboni, Cristina; Iannitto, Ml; Ricciardi, Maria Rosaria; Di Gialleonardo, V; Cippitelli, Marco; Fionda, Cinzia; Petrucci, Mt; Guarini, Anna; Foa, Roberto; Santoni, Angela - 01a Articolo in rivista
paper: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 3503-3511 - issn: 0006-4971 - wos: WOS:000265052300016 (350) - scopus: 2-s2.0-65349131915 (364)

11573/501218 - 2008 - When damage prevents cancer: the activation of the DNA damage response regulate the expression of DNAM-1 and NKG2D activating receptor ligands on human multiple myeloma cells
Soriani, Alessandra; Cerboni, Cristina; Zingoni, Alessandra; Di Gialleonardo, V.; Cippitelli, Marco; Fionda, Cinzia; Ricciardi, Maria Rosaria; Petrucci, M. T.; Guarini, R.; Foa, Roberto; Santoni, Angela - 04d Abstract in atti di convegno
paper: MINERVA MEDICA (Edizioni Minerva Medica:Corso Bramante 83-85, 10126 Turin Italy:011 39 011 678282318, EMAIL: journals.dept@minervamedica.it, INTERNET: http://www.minervamedica.it, Fax: 011 39 011 674502) pp. 46-46 - issn: 0026-4806 - wos: (0) - scopus: (0)
conference: 6th national conference SIICA (Rome)

11573/56523 - 2008 - The activation of the DNA damage response regulate the expression of DNAM-1 and NKG2D activating receptor ligands on human multiple myeloma (MM) cells.
Soriani, Alessandra; Zingoni, Alessandra; Cerboni, Cristina; V., Di Gialleonardo; Cippitelli, Marco; Fionda, Cinzia; Ricciardi, Maria Rosaria; M. T., Petrucci; R., Guarini; Foà, R.; Santoni, Angela - 04a Atto di comunicazione a congresso
paper: THE AMERICAN JOURNAL OF PATHOLOGY (American Society for Investigative Pathology:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7130, EMAIL: asjp@asip.org, INTERNET: http://www.asip.org, Fax: (301)634-7990) pp. - - issn: 0002-9440 - wos: (0) - scopus: (0)

11573/361929 - 2007 - 15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors.
Fionda, Cinzia; F., Nappi; Piccoli, Mario; Frati, Luigi; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 4039-4050 - issn: 0022-1767 - wos: WOS:000245197300008 (14) - scopus: 2-s2.0-33947665437 (14)

11573/365115 - 2007 - Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) in T lymphocytes
Fionda, Cinzia; Nappi, F; Piccoli, Mario; Frati, Luigi; Santoni, Angela; Cippitelli, Marco - 01a Articolo in rivista
paper: MOLECULAR PHARMACOLOGY (American Society for Pharmacology and Experimental Therapeutics:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7024, EMAIL: pstoute@aspet.org, INTERNET: http://www.aspet.org, Fax: (301)634-7099) pp. 1246-1257 - issn: 0026-895X - wos: WOS:000250385300018 (12) - scopus: 2-s2.0-35548979142 (14)

11573/366904 - 2006 - Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway.
Di Bona, D; Cippitelli, Marco; Fionda, Cinzia; Camma, C; Licata, A; Santoni, Angela; Craxi, A. - 01a Articolo in rivista
paper: JOURNAL OF HEPATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 271-279 - issn: 0168-8278 - wos: WOS:000239545700016 (77) - scopus: 2-s2.0-33745580391 (87)

11573/358219 - 2005 - Hyperthermia enhances CD95-ligand gene expression in T lymphocytes
Cippitelli, Marco; Fionda, Cinzia; Di Bona, D.; Piccoli, Mario; Frati, Luigi; Santoni, Angela; Equally Contributed, °Cippitelli M. And Fionda C. - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 223-232 - issn: 0022-1767 - wos: WOS:000225852900026 (38) - scopus: 2-s2.0-10844242970 (37)

11573/362184 - 2003 - The cyclopentenone-type prostaglandin 15-deoxy-delta12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms
Cippitelli, Marco; Fionda, Cinzia; Di Bona, D.; Lupo, A.; Piccoli, Mario; Frati, L.; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 4578-4592 - issn: 0022-1767 - wos: WOS:000182528100023 (29) - scopus: 2-s2.0-0037408301 (30)

11573/365267 - 2002 - Negative regulation of CD95-ligand gene expression by vitamin D3 in T lymphocytes.
Cippitelli, Marco; Fionda, Cinzia; Di Bona, D; Di Rosa, F; Lupo, A; Piccoli, Mario; Frati, Luigi; Santoni, Angela - 01a Articolo in rivista
paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 1154-1166 - issn: 0022-1767 - wos: WOS:000173429300024 (59) - scopus: 2-s2.0-0036467478 (71)

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