Education Background
1975-1978 - B.Sc. (First Class Honour), The University of Hong Kong.
1978-1980 - Ph.D. in Inorganic Chemistry, The University of Hong Kong.
(Supervisor: Professor Chung-Kwong Poon).
1980-1983 - Research in Organometallic Photochemistry and Bioinorganic Chemistry,
California Institute of Technology.
(Supervisor: Professor Harry B. Gray).
Academic and Working Experience
Member : American Chemical Society, Royal Society of Chemistry
1994–1997 Advisory Committee, Institution of Chemistry, Academia Sinica, Taiwan,
Chinese Academy of Sciences, China (elected in 1995). (The first Hong Kong citizen elected to Chinese Academy of Sciences)
Fellow:
- The Royal Society of Chemistry
-The Academy of Sciences for the Developing World (TWAS)
-Federation of Asian Chemical Societies
-Foreign Fellow of National Academy of Sciences, USA (elected in 2013)
Lecturer: The University of Hong Kong, August 1983–August 1990
Reader: The University of Hong Kong, September 1990–October 1992
Chair Professor: The University of Hong Kong, November 1992–present
Visiting Professor:
- Chemistry Department, National Taiwan University, July 1990 to June 1994
-Jilin University, China (1996)
-Sun Yat-Sen University (2004–2007)
Honorary Professor:
-Institute of Photographic Chemistry, Chinese Academy of Sciences, China (1997)
- State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Chemistry, Chinese Academy of Sciences, China (1996)
- Huazhong University of Science and Technology (1999)
- Northeast Normal University (2002)
- Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, China (2012)
Professor:
- Chemistry Department, Nanjing University, China (1996-present)
- Chemistry Department, Nankai University, China (1996)
- Chemistry Department, Tsing Hua University, China (20092012)
Guest Professor: Peking University, China (1996)
- Director HKU-CAS Joint Laboratory on New Materials, The University of Hong Kong (2001–present)
- State Key Laboratory of Synthetic Chemistry, The University of Hong Kong (2011–present)
Visiting Research Associate:
-California Institute of Technology, Summer Vacations of 1984–1988
Visiting Scientist :
-Invited by National Science Council of Taiwan and hosted by National Taiwan University, July–August of 1989 and April 2009
- National Research Council of Italy (2004)
Editor-in-chief:
- Advances in Transition Metal Coordination Chemistry, JAI
International Advisory Editorial Board Member:
-Journal of the Chemical Society, Dalton Transactions (1998–2002)
- New Journal of Chemistry (1998–2000)
- European Journal of Inorganic Chemistry (2001–2006)
-Chemistry – A European Journal (2001–present)
- Chemistry – An Asian Journal (2006–present)
- Inorganic Chemistry (2012–present)
- ChemCatChem (2009–present)
- Journal of Inorganic Biochemistry (2009–present)
- Chemical Science (2010–present)
- ChemPlusChem (2011–present)
Chemmical Communications (2013–present)
-Inorganic Chemistry (2013–present)
-Coordination Chemistry Reviews (2014-present)
Awards and Honor
[1] 1994 State Natural Science Award of China (The 3rd Class Prize)
[2] 1995 Elected to Member of Chinese Academy of Sciences, Chinan
[3] 1997 Croucher Senior Fellowship Award from the Croucher Foundation of Hong Kong
[4] 1997 Chung-Hsing S&T Lecturership, Taiwan
[5] 2000 Distinguished Research Achievement Award honored by The University of Hong Kong
[6] National Outstanding Young Scholar Award, The National Science Foundation of China, 2000-2003
[7] IUF Invited Professorship, France
[8] 2003 Federation of Asian Chemical Societies (FACS) Foundation Lectureship Award
[9] 2004 Visiting Scientist Award of National Research Council of Italy
[10] Admitted to Fellow of The World Innovation Foundation
[11] 2005 Admitted to Fellow of Federation of Asian Chemical Societies
[12] Listed as ISI Highly Cited Researcher by ISIHighlyCited.com
[13] Ranked 21st in a list of the world’s top 40 most cited authors for their papers published in the widely-read journal Chemical Communications between 1965 and
2004; interviewed by Chemical Communications
[14] 2006 TWAS Prize in Chemistry from the Academy of Sciences for the Developing World
[15] Pfizer Lectureship at the Sixth International Symposium for Chinese Organic Chemists (ISCOC-6) and Ninth International Symposium for Chinese Inorganic
Chemists (ISCIC-9)
[16] The First Class Prize of the State Natural Science Award of China
[17] 2007 Seaborg Lectureship at the University of California at Berkeley
[18] Prize of Ho Leung Ho Lee (HLHL) Foundation for Scientific and Technological Progress
[19] Elected to Fellow of the Academy of Sciences for the Developing World (TWAS)
[20] 2008 Leader of the Year 2007 Prize, Hong Kong SAR.
[21] Julia S. and Edward C. Lee Lectureship at University of Chicago
[22] 2009 Admitted as Fellow of The Royal Society of Chemistry
[23] HKU Science Distinguished Alumni
[24] KC Wong Education Foundation Lecturership
[25] 2010 Nanqiang Lecturership at Xiamen University
[26] 2011 Fudan Advisory Professorship at Fudan University
[27] 2013 Centurary Prize of the Royal Society of Chemistry
[28] Elected as Foreign Fellow of National Academy of Sciences, USA
[29] Davison Lectureship at Massachusetts Institute of Technology
Research Interests
Inorganic and Organic Synthesis, Metal Ions Promoted Organic Transformations, Organometallic and Inorganic Photochemistry, Electron Transfer Reactions in Biological Systems, Chiral Metal Catalysts, Asymmetric Organic Oxidations, Highly Reactive Metal-Carbon Multiple Bonded Complexes, Luminescent Materials, Bioinorganic Chemistry, and Inorganic Medicines
Publications in the last 5 years
(1) Liang, X.; Zhang, F.; Yan, Z.-P.; Wu, Z.-G.; Zheng, Y.; Cheng, G.; Wang, Y.; Zuo, J.-L.; Pan, Y.; Che, C.-M. Fast Synthesis of Iridium(III) Complexes Incorporating a Bis(Diphenylphorothioyl)Amide Ligand for Efficient Pure Green OLEDs. ACS Appl. Mater. Interfaces 2019, 11 (7), 7184–7191. https://doi.org/10.1021/acsami.8b19318.
(2) Lee, P.; Lok, C.-N.; Che, C.-M.; Kao, W. J. A Multifunctional Hydrogel Delivers Gold Compound and Inhibits Human Lung Cancer Xenograft. Pharm. Res. 2019, 36 (4), 61. https://doi.org/10.1007/s11095-019-2581-z.
(3) Lee, C. L.; Wu, L.; Huang, J.-S.; Che, C.-M. Stable Iridium(Iv) Complexes Supported by Tetradentate Salen Ligands. Synthesis, Structures and Reactivity. Chem. Commun. Camb. Engl. 2019. https://doi.org/10.1039/c8cc10220a.
(4) Lam, T.-L.; Tong, K.-C.; Yang, C.; Kwong, W.-L.; Guan, X.; Li, M.-D.; Kar-Yan Lo, V.; Lai-Fung Chan, S.; Lee Phillips, D.; Lok, C.-N.; et al. Luminescent Ruffled Iridium(Iii) Porphyrin Complexes Containing N-Heterocyclic Carbene Ligands: Structures, Spectroscopies and Potent Antitumor Activities under Dark and Light Irradiation Conditions. Chem. Sci. 2019, 10 (1), 293–309. https://doi.org/10.1039/c8sc02920b.
(5) Du, Y.-D.; Xu, Z.-J.; Zhou, C.-Y.; Che, C.-M. An Effective [FeIII(TF4DMAP)Cl] Catalyst for C-H Bond Amination with Aryl and Alkyl Azides. Org. Lett. 2019, 21 (4), 895–899. https://doi.org/10.1021/acs.orglett.8b03765.
(6) Zou, T.; Lok, C.-N.; Wan, P.-K.; Zhang, Z.-F.; Fung, S.-K.; Che, C.-M. Anticancer Metal-N-Heterocyclic Carbene Complexes of Gold, Platinum and Palladium. Curr. Opin. Chem. Biol. 2018, 43, 30–36. https://doi.org/10.1016/j.cbpa.2017.10.014.
(7) Zhang, L.-L.; Wang, X.-Y.; Jiang, K.-Y.; Zhao, B.-Y.; Yan, H.-M.; Zhang, X.-Y.; Zhang, Z.-X.; Guo, Z.; Che, C.-M. A Theoretical Study on the Oxidation of Alkenes to Aldehydes Catalyzed by Ruthenium Porphyrins Using O2 as the Sole Oxidant. Dalton Trans. Camb. Engl. 2003 2018, 47 (15), 5286–5297. https://doi.org/10.1039/C8DT00614H.
(8) Yuan, J.; To, W.-P.; Zhang, Z.-Y.; Yue, C.-D.; Meng, S.; Chen, J.; Liu, Y.; Yu, G.-A.; Che, C.-M. Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium Tert-Butoxide. Org. Lett. 2018. https://doi.org/10.1021/acs.orglett.8b03265.
(9) Wu, K.; Zhou, C.-Y.; Che, C.-M. Perfluoroalkyl Aziridines with Ruthenium Porphyrin Carbene Intermediates. Org. Lett. 2018. https://doi.org/10.1021/acs.orglett.8b03514.
(10) Wu, K.; Cao, B.; Zhou, C.-Y.; Che, C.-M. RhII -Catalyzed Intermolecular C-H Arylation of Aromatics with Diazo Quinones. Chem. Weinh. Bergstr. Ger. 2018, 24 (19), 4815–4819. https://doi.org/10.1002/chem.201800648.
(11) Wang, E.-H.; Ping, Y.-J.; Li, Z.-R.; Qin, H.; Xu, Z.-J.; Che, C.-M. Iron Porphyrin Catalyzed Insertion Reaction of N-Tosylhydrazone-Derived Carbenes into X-H (X = Si, Sn, Ge) Bonds. Org. Lett. 2018, 20 (15), 4641–4644. https://doi.org/10.1021/acs.orglett.8b01931.
(12) Wan, Q.; Xiao, X.-S.; To, W.-P.; Lu, W.; Chen, Y.; Low, K.-H.; Che, C.-M. Counteranion- and Solvent-Mediated Chirality Transfer in the Supramolecular Polymerization of Luminescent Platinum(II) Complexes. Angew. Chem. Int. Ed Engl. 2018, 57 (52), 17189–17193. https://doi.org/10.1002/anie.201811943.
(13) Wan, Q.; To, W.-P.; Yang, C.; Che, C.-M. The Metal-Metal-to-Ligand Charge Transfer Excited State and Supramolecular Polymerization of Luminescent Pincer PdII -Isocyanide Complexes. Angew. Chem. Int. Ed Engl. 2018, 57 (12), 3089–3093. https://doi.org/10.1002/anie.201712249.
(14) Tse, C.-W.; Liu, Y.; Wai-Shan Chow, T.; Ma, C.; Yip, W.-P.; Chang, X.-Y.; Low, K.-H.; Huang, J.-S.; Che, C.-M. Cis-Oxoruthenium Complexes Supported by Chiral Tetradentate Amine (N4) Ligands for Hydrocarbon Oxidations. Chem. Sci. 2018, 9 (10), 2803–2816. https://doi.org/10.1039/c7sc05224c.
(15) Sun, C.-Y.; To, W.-P.; Hung, F.-F.; Wang, X.-L.; Su, Z.-M.; Che, C.-M. Metal-Organic Framework Composites with Luminescent Pincer Platinum(Ii) Complexes: 3MMLCT Emission and Photoinduced Dehydrogenation Catalysis. Chem. Sci. 2018, 9 (8), 2357–2364. https://doi.org/10.1039/c7sc04528j.
(16) Shing, K.-P.; Liu, Y.; Cao, B.; Chang, X.-Y.; You, T.; Che, C.-M. N-Heterocyclic Carbene Iron(III) Porphyrin-Catalyzed Intramolecular C(Sp3 )-H Amination of Alkyl Azides. Angew. Chem. Int. Ed Engl. 2018, 57 (37), 11947–11951. https://doi.org/10.1002/anie.201806059.
(17) Shing, K.-P.; Cao, B.; Liu, Y.; Lee, H. K.; Li, M.-D.; Phillips, D. L.; Chang, X.-Y.; Che, C.-M. Arylruthenium(III) Porphyrin-Catalyzed C-H Oxidation and Epoxidation at Room Temperature and [RuV(Por)(O)(Ph)] Intermediate by Spectroscopic Analysis and Density Functional Theory Calculations. J. Am. Chem. Soc. 2018, 140 (22), 7032–7042. https://doi.org/10.1021/jacs.8b04470.
(18) Shi, R.; Ye, H.-F.; Liang, F.; Wang, Z.; Li, K.; Weng, Y.; Lin, Z.; Fu, W.-F.; Che, C.-M.; Chen, Y. Interstitial P-Doped CdS with Long-Lived Photogenerated Electrons for Photocatalytic Water Splitting without Sacrificial Agents. Adv. Mater. Deerfield Beach Fla 2018, 30 (6). https://doi.org/10.1002/adma.201705941.
(19) Qin, L.; Guan, X.; Yang, C.; Huang, J.-S.; Che, C.-M. Near-Infrared Phosphorescent Supramolecular Alkyl/Aryl-Iridium Porphyrin Assemblies by Axial Coordination. Chem. Weinh. Bergstr. Ger. 2018, 24 (54), 14400–14408. https://doi.org/10.1002/chem.201803238.
(20) Luo, X.; Yuan, J.; Yue, C.-D.; Zhang, Z.-Y.; Chen, J.; Yu, G.-A.; Che, C.-M. Synthesis of Peri-Substituted (Naphthalen-1-Yl)Phosphine Ligands by Rhodium(I)-Catalyzed Phosphine-Directed C-H Arylation. Org. Lett. 2018, 20 (7), 1810–1814. https://doi.org/10.1021/acs.orglett.8b00305.
(21) Liu, Q.; Xie, M.; Chang, X.; Cao, S.; Zou, C.; Fu, W.-F.; Che, C.-M.; Chen, Y.; Lu, W. Tunable Multicolor Phosphorescence of Crystalline Polymeric Complex Salts with Metallophilic Backbones. Angew. Chem. Int. Ed Engl. 2018, 57 (21), 6279–6283. https://doi.org/10.1002/anie.201803965.
(22) Li, P.; Fung, Y.-M. E.; Yin, X.; Seneviratne, C. J.; Che, C.-M.; Jin, L. Controlled Cellular Redox, Repressive Hemin Utilization and Adaptive Stress Responses Are Crucial to Metronidazole Tolerance of Porphyromonas Gingivalis Persisters. J. Clin. Periodontol. 2018, 45 (10), 1211–1221. https://doi.org/10.1111/jcpe.13002.
(23) Li, K.; Wan, Q.; Yang, C.; Chang, X.-Y.; Low, K.-H.; Che, C.-M. Air-Stable Blue Phosphorescent Tetradentate Platinum(II) Complexes as Strong Photo-Reductant. Angew. Chem. Int. Ed Engl. 2018, 57 (43), 14129–14133. https://doi.org/10.1002/anie.201808642.
(24) Chang, I.-S.; Sy, L.-K.; Cao, B.; Lum, C. T.; Kwong, W.-L.; Fung, Y.-M. E.; Lok, C.-N.; Che, C.-M. Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus Effusus. J. Proteome Res. 2018, 17 (7), 2470–2479. https://doi.org/10.1021/acs.jproteome.8b00227.
(25) Zhong, J.-J.; Yang, C.; Chang, X.-Y.; Zou, C.; Lu, W.; Che, C.-M. Platinum(Ii) Photo-Catalysis for Highly Selective Difluoroalkylation Reactions. Chem. Commun. Camb. Engl. 2017, 53 (64), 8948–8951. https://doi.org/10.1039/c7cc03823b.
(26) Yeung, K.-T.; To, W.-P.; Sun, C.; Cheng, G.; Ma, C.; Tong, G. S. M.; Yang, C.; Che, C.-M. Luminescent Tungsten(VI) Complexes: Photophysics and Applicability to Organic Light-Emitting Diodes and Photocatalysis. Angew. Chem. Int. Ed Engl. 2017, 56 (1), 133–137. https://doi.org/10.1002/anie.201608240.
(27) Tso, K. C.-H.; Chan, S. L.-F.; Huang, J.-S.; Che, C.-M. Wheel-to-Rhomboid Isomerization as Well as Nitrene Transfer Catalysis of Ruthenium-Thiolate Wheels. Chem. Commun. Camb. Engl. 2017, 53 (16), 2419–2422. https://doi.org/10.1039/c6cc09903c.
(28) To, W.-P.; Zhou, D.; Tong, G. S. M.; Cheng, G.; Yang, C.; Che, C.-M. Highly Luminescent Pincer Gold(III) Aryl Emitters: Thermally Activated Delayed Fluorescence and Solution-Processed OLEDs. Angew. Chem. Int. Ed Engl. 2017, 56 (45), 14036–14041. https://doi.org/10.1002/anie.201707193.
(29) To, W.-P.; Tong, G. S. M.; Cheung, C.-W.; Yang, C.; Zhou, D.; Che, C.-M. Luminescent Cyclometalated Gold(III) Alkyl Complexes: Photophysical and Photochemical Properties. Inorg. Chem. 2017, 56 (9), 5046–5059. https://doi.org/10.1021/acs.inorgchem.7b00180.
(30) So, G. K.-M.; Cheng, G.; Wang, J.; Chang, X.; Kwok, C.-C.; Zhang, H.; Che, C.-M. Efficient Color-Tunable Copper(I) Complexes and Their Applications in Solution-Processed Organic Light-Emitting Diodes. Chem. Asian J. 2017, 12 (13), 1490–1498. https://doi.org/10.1002/asia.201700081.
(31) Ng, V. Y.-M.; Tse, C.-W.; Guan, X.; Chang, X.; Yang, C.; Low, K.-H.; Lee, H. K.; Huang, J.-S.; Che, C.-M. Cis-Dioxorhenium(V/VI) Complexes Supported by Neutral Tetradentate N4 Ligands. Synthesis, Characterization, and Spectroscopy. Inorg. Chem. 2017, 56 (24), 15066–15080. https://doi.org/10.1021/acs.inorgchem.7b02404.
(32) Lam, T. L.; Tso, K. C.-H.; Cao, B.; Yang, C.; Chen, D.; Chang, X.-Y.; Huang, J.-S.; Che, C.-M. Tripodal S-Ligand Complexes of Copper(I) as Catalysts for Alkene Aziridination, Sulfide Sulfimidation, and C-H Amination. Inorg. Chem. 2017, 56 (8), 4253–4257. https://doi.org/10.1021/acs.inorgchem.7b00226.
(33) Fung, S. K.; Zou, T.; Cao, B.; Lee, P.-Y.; Fung, Y. M. E.; Hu, D.; Lok, C.-N.; Che, C.-M. Cyclometalated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets. Angew. Chem. Int. Ed Engl. 2017, 56 (14), 3892–3896. https://doi.org/10.1002/anie.201612583.
(34) Fu, Z.-C.; Xu, Y.; Chan, S. L.-F.; Wang, W.-W.; Li, F.; Liang, F.; Chen, Y.; Lin, Z.-S.; Fu, W.-F.; Che, C.-M. Highly Efficient Hydrolysis of Ammonia Borane by Anion (-OH, F-, Cl-)-Tuned Interactions between Reactant Molecules and CoP Nanoparticles. Chem. Commun. Camb. Engl. 2017, 53 (4), 705–708. https://doi.org/10.1039/c6cc08120g.
(35) Chung, C. Y.-S.; Fung, S.-K.; Tong, K.-C.; Wan, P.-K.; Lok, C.-N.; Huang, Y.; Chen, T.; Che, C.-M. A Multi-Functional PEGylated Gold(Iii) Compound: Potent Anti-Cancer Properties and Self-Assembly into Nanostructures for Drug Co-Delivery. Chem. Sci. 2017, 8 (3), 1942–1953. https://doi.org/10.1039/c6sc03210a.
(36) Chang, X.-Y.; Xu, G.-T.; Cao, B.; Wang, J.-Y.; Huang, J.-S.; Che, C.-M. Assembly of Strongly Phosphorescent Hetero-Bimetallic and -Trimetallic [2]Catenane Structures Based on a Coinage Metal Alkynyl System. Chem. Sci. 2017, 8 (11), 7815–7820. https://doi.org/10.1039/c7sc03529b.
(37) Chan, K. T.; Tong, G. S. M.; Wan, Q.; Cheng, G.; Yang, C.; Che, C.-M. Strongly Luminescent Cyclometalated Gold(III) Complexes Supported by Bidentate Ligands Displaying Intermolecular Interactions and Tunable Emission Energy. Chem. Asian J. 2017, 12 (16), 2104–2120. https://doi.org/10.1002/asia.201700686.
(38) Chan, K. T.; Tong, G. S. M.; To, W.-P.; Yang, C.; Du, L.; Phillips, D. L.; Che, C.-M. The Interplay between Fluorescence and Phosphorescence with Luminescent Gold(i) and Gold(Iii) Complexes Bearing Heterocyclic Arylacetylide Ligands. Chem. Sci. 2017, 8 (3), 2352–2364. https://doi.org/10.1039/c6sc03775e.
(39) Cao, T.-T.; Lin, S.-H.; Fu, L.; Tang, Z.; Che, C.-M.; Zhang, L.-Y.; Ming, X.-Y.; Liu, T.-F.; Tang, X.-M.; Tan, B.-B.; et al. Eukaryotic Translation Initiation Factor 5A2 Promotes Metabolic Reprogramming in Hepatocellular Carcinoma Cells. Carcinogenesis 2017, 38 (1), 94–104. https://doi.org/10.1093/carcin/bgw119.
(40) Wang, F.; Lan, M.; To, W.-P.; Li, K.; Lok, C.-N.; Wang, P.; Che, C.-M. A Macromolecular Cyclometalated Gold(Iii) Amphiphile Displays Long-Lived Emissive Excited State in Water: Self-Assembly and in Vitro Photo-Toxicity. Chem. Commun. Camb. Engl. 2016, 52 (90), 13273–13276. https://doi.org/10.1039/c6cc06767k.
(41) Zou, T.; Lum, C. T.; Lok, C.-N.; Zhang, J.-J.; Che, C.-M. Chemical Biology of Anticancer Gold(III) and Gold(I) Complexes. Chem. Soc. Rev. 2015, 44 (24), 8786–8801. https://doi.org/10.1039/c5cs00132c.
(42) Xu, C.; Cai, Y.; Fan, P.; Bai, B.; Chen, J.; Deng, H.-B.; Che, C.-M.; Xu, A.; Vanhoutte, P. M.; Wang, Y. Calorie Restriction Prevents Metabolic Aging Caused by Abnormal SIRT1 Function in Adipose Tissues. Diabetes 2015, 64 (5), 1576–1590. https://doi.org/10.2337/db14-1180.
(43) Wang, B.; Shelar, D. P.; Han, X.-Z.; Li, T.-T.; Guan, X.; Lu, W.; Liu, K.; Chen, Y.; Fu, W.-F.; Che, C.-M. Long-Lived Excited States of Zwitterionic Copper(I) Complexes for Photoinduced Cross-Dehydrogenative Coupling Reactions. Chem. Weinh. Bergstr. Ger. 2015, 21 (3), 1184–1190. https://doi.org/10.1002/chem.201405356.
(44) Tsai, J. L.-L.; Zou, T.; Liu, J.; Chen, T.; Chan, A. O.-Y.; Yang, C.; Lok, C.-N.; Che, C.-M. Luminescent Platinum(Ii) Complexes with Self-Assembly and Anti-Cancer Properties: Hydrogel, PH Dependent Emission Color and Sustained-Release Properties under Physiological Conditions. Chem. Sci. 2015, 6 (7), 3823–3830. https://doi.org/10.1039/c4sc03635b.
(45) Tsai, J. L.-L.; Chan, A. O.-Y.; Che, C.-M. A Luminescent Cyclometalated Gold(Iii)-Avidin Conjugate with a Long-Lived Emissive Excited State That Binds to Proteins and DNA and Possesses Anti-Proliferation Capacity. Chem. Commun. Camb. Engl. 2015, 51 (40), 8547–8550. https://doi.org/10.1039/c5cc00186b.
(46) Ming Tong, G. S.; Chan, K. T.; Chang, X.; Che, C.-M. Theoretical Studies on the Photophysical Properties of Luminescent Pincer Gold(Iii) Arylacetylide Complexes: The Role of π-Conjugation at the C-Deprotonated [C^N^C] Ligand. Chem. Sci. 2015, 6 (5), 3026–3037. https://doi.org/10.1039/c4sc03697b.
(47) Lo, V. K.-Y.; Chan, A. O.-Y.; Che, C.-M. Gold and Silver Catalysis: From Organic Transformation to Bioconjugation. Org. Biomol. Chem. 2015, 13 (24), 6667–6680. https://doi.org/10.1039/c5ob00407a.
(48) Li, K.; Zou, T.; Chen, Y.; Guan, X.; Che, C.-M. Pincer-Type Platinum(II) Complexes Containing N-Heterocyclic Carbene (NHC) Ligand: Structures, Photophysical and Anion-Binding Properties, and Anticancer Activities. Chem. Weinh. Bergstr. Ger. 2015, 21 (20), 7441–7453. https://doi.org/10.1002/chem.201406453.
(49) Lau, S.-T.; Zhou, T.; Liu, J. A.-J.; Fung, E. Y.-M.; Che, C.-M.; Lang, B. H.-H.; Ngan, E. S.-W. Dysregulation of Clathrin Promotes Thyroid Cell Growth and Contributes to Multinodular Goiter Pathogenesis. Biochim. Biophys. Acta 2015, 1852 (8), 1676–1686. https://doi.org/10.1016/j.bbadis.2015.05.005.
(50) Kwong, W.-L.; Lok, C.-N.; Tse, C.-W.; Wong, E. L.-M.; Che, C.-M. Anti-Cancer Iron(II) Complexes of Pentadentate N-Donor Ligands: Cytotoxicity, Transcriptomics Analyses, and Mechanisms of Action. Chem. Weinh. Bergstr. Ger. 2015, 21 (7), 3062–3072. https://doi.org/10.1002/chem.201404749.
(51) Guo, Y.; Xu, L.; Liu, H.; Li, Y.; Che, C.-M.; Li, Y. Self-Assembly of Functional Molecules into 1D Crystalline Nanostructures. Adv. Mater. Deerfield Beach Fla 2015, 27 (6), 985–1013. https://doi.org/10.1002/adma.201403846.
(52) Chow, P.-K.; Cheng, G.; Tong, G. S. M.; To, W.-P.; Kwong, W.-L.; Low, K.-H.; Kwok, C.-C.; Ma, C.; Che, C.-M. Luminescent Pincer Platinum(II) Complexes with Emission Quantum Yields up to Almost Unity: Photophysics, Photoreductive C-C Bond Formation, and Materials Applications. Angew. Chem. Int. Ed Engl. 2015, 54 (7), 2084–2089. https://doi.org/10.1002/anie.201408940.
(53) Cheng, G.; So, G. K.-M.; To, W.-P.; Chen, Y.; Kwok, C.-C.; Ma, C.; Guan, X.; Chang, X.; Kwok, W.-M.; Che, C.-M. Luminescent Zinc(Ii) and Copper(i) Complexes for High-Performance Solution-Processed Monochromic and White Organic Light-Emitting Devices. Chem. Sci. 2015, 6 (8), 4623–4635. https://doi.org/10.1039/c4sc03161j.
(54) Chen, Y.; Che, C.-M.; Lu, W. Phosphorescent Organoplatinum(II) Complexes with a Lipophilic Anion: Supramolecular Soft Nanomaterials through Ionic Self-Assembly and Metallophilicity. Chem. Commun. Camb. Engl. 2015, 51 (25), 5371–5374. https://doi.org/10.1039/c4cc08569h.