Research: Romosozumab and Systemic Frailty: A Longitudinal Study of Bone, Immune and Endothelial Biomarkers
WORK EXPERIENCE:
- Medical Doctor, Specialist in Endocrinology and Metabolic Diseases
- Medical Doctor, AOU Policlinico Umberto I - Rome (IT) - DSATOB TOBIA Project (Internal Medicine)
- PhD Candidate in Endocrinological Sciences (XLI cycle), Department of Experimental Medicine, Sapienza University of Rome (Supervisor: Prof. Elisa Giannetta)
RESEARCH ACTIVITY:
- Clinical activity and clinical research in endocrinology, with particular interest in metabolic bone diseases (osteoporosis, Paget’s disease of bone, osteogenesis imperfecta, fibrous dysplasia, complex regional pain syndrome, hypophosphatasia), disorders of calcium metabolism and parathyroid diseases (primary hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism), thyroid diseases (nodular thyroid disease, hyperthyroidism, hypothyroidism), and neck ultrasound diagnostics.
EDUCATION:
- PhD in Endocrinological Sciences (XLI cycle), Department of Experimental Medicine, Sapienza University of Rome (Nov. 2025 – present)
- Residency in Endocrinology and Metabolic Diseases, Department of Experimental Medicine, Sapienza University of Rome (Nov. 2021 – Nov. 2025)
- Degree in Medicine and Surgery, Sapienza University of Rome (2015 – 2021)
PUBLICATIONS AND ABSTRACTS:
- 2025 – Cabozantinib in the Treatment of Neuroendocrine Neoplasms: Insights Across Different Tumor Origins "Vitale G., Arrivi G., Filice A., Nardi C., Faggiano A."
Review article – Neuroendocrinology
- 2025 – Breaking Down Bone Disease in People Living with HIV: Pathophysiology, Diagnosis, and Treatment "Hasenmajer V., D’Addario N.F., Bonaventura I., Sada V., Nardi C., D’Ettorre G., Mastroianni C.M., Gianfrilli D." Book chapter – Advances in Experimental Medicine and Biology
- 2024 – Detection of Spermatozoa in a Patient with Klinefelter Syndrome with XXY/XX Mosaicism "Tahani N., Cargnelutti F., Spaziani M., Nardi C., Paoli D., Isidori A."
Abstract in conference – IIEM 2024 Italian Meetings of Endocrinology and Metabolism (Genoa)
2023 – C-Cell Hyperplasia and Cystic Papillary Thyroid Carcinoma in a Patient with Type 1B Pseudohypoparathyroidism and Hypercalcitoninaemia: Case Report and Review of the Literature "Pandozzi C., Filice A., Nardi C., et al." Journal of Clinical Medicine
PARTICIPATION IN CLINICAL TRIALS
- Sub-Investigator in the clinical trial “IMVT1402-2503- FORWARD2 – A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves’ Disease” (2026 – ongoing);
- Sub-Investigator in the clinical trial “TCH306: ForesiGHt – A Multicenter, Randomized, Parallel-arm, Placebo-controlled (Double-Blind) and Active-controlled (Open-label) Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency” (2022 – 2024)
- Sub-Investigator in the clinical trial (extension study) “TCH-306EXT – A Multicenter, Open-Label Extension Trial to Investigate Long-Term Efficacy and Safety of Lonapegsomatropin in Adults with Growth Hormone Deficiency” (2023 – 2025)