Phd in MOLECULAR DESIGN AND CHARACTERIZATION FOR THE
PROMOTION OF HEALTH AND WELL-BEING: FROM DRUG TO FOOD

email: chiara.dimeo@uniroma1.it
phone: 0649913961
building: CU019
room: 261

Academic positions
2018 - , Associate Professor in Pharmaceutical Technology (Chim/09), Department of Drug Chemistry and Technologies, Sapienza University of Rome
2015-2018, Researcher RTDB, Department of Drug Chemistry and Technologies, Sapienza University of Rome
2014-2015 Post-doc, Department of Drug Chemistry and Technologies, Sapienza University of Rome
2011-2014, Researcher RTDM, Department of Drug Chemistry and Technologies, Sapienza University of Rome
2009-2010, Visiting Post-doc at the UMR CNRS 8612 (Physico-Chimie - Pharmacotechnie – Biopharmacie) laboratory, Faculty of Pharmacy, University of Paris-Sud XI
2007-2011, Post-doc, Department of Drug Chemistry and Technologies, Sapienza University of Rome
2007, Post-doc, Department of Chemistry, Sapienza University of Rome

Education
2006, Ph.D. in Industrial Chemical Processes, Sapienza University of Rome
2002, Master's Degree in Industrial Chemistry, Sapienza University of Rome

Teaching
2012 - , Polymers for Pharmaceutics, Faculty of Pharmacy and Medicine, Sapienza University of Rome
2019 - ,Chemistry of Cosmetic Products, Faculty of Pharmacy and Medicine, Sapienza University of Rome

Research Activities
• Development of self-assembling nanogels based on hydrophobic derivatives of polysaccharides for applications in drug delivery: derivatization of biocompatible and bioactive polysaccharides with hydrophobic molecules to obtain the development of self-assembling nanostructures in aqueous medium (nanogels). Such nanostructures, stable and non-cytotoxic, are studied as carriers of drugs or proteins in anticancer, antibiotic, anti-inflammatory therapies.
• Synthesis and physico-chemical characterization of polysaccharide matrices in the gel phase and study of their potential use as drug delivery systems (DDS): development of gel polysaccharide matrices (both chemical and physical, in the form of massive hydrogels, injectable gels, beads, microspheres) for applications in the modified drug release, and their structural (NMR, SAXS) and mechanical (rheology, dynamometry) characterization. Study of the release kinetics of biologically active molecules, small molecules or therapeutic proteins, from hydrogels in hydrated or dried form.
• Synthesis and physico-chemical characterization of polymeric prodrugs: development of pharmacologically active derivatives based on hyaluronic acid and their physico-chemical characterization by means of spectrophotometric and spectroscopic techniques.