11573/1773408 - 2026 -
Molecular striptease of a thiadiazolopyrimidine hit yields a streamlined, artifact-free NADPH mimic for NOX inhibition Fabbrizi, Emanuele; Mancini, Andrea; Lambona, Chiara; Macrì, Salvatore; Nalli, Marianna; Quilli, Francesco; Pandolfi, Federico; Raimondo, Domenico; Marchese, Sara; Mattevi, Andrea; Lee, Jihyeon; Choi, Minhye; Soo Bae, Yun; Hristova-Avakumova, Nadya; Kondeva-Burdina, Magdalena; Stefanova, Denitsa; Anastassova, Neda; Valente, Sergio; Rotili, Dante; Mai, Antonello - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. - - issn: 1948-5875 - wos: WOS:001845908400001 (0) - scopus: (0)
11573/1775149 - 2026 -
Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones. Effects in HIV-1 infected cells and reverse transcriptase enzymes Degtyarenko, Egor; Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Astolfi, Roberta; Giuliani, Lidia; Mancini, Andrea; Nawrozkij, Maxim B; Chernyshov, Vladimir; Pupillo, Clarissa; Cirilli, Roberto; Bavagnoli, Laura; Ragno, Rino; Esté, José A; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. 1-18 - issn: 1768-3254 - wos: WOS:001875392200001 (0) - scopus: 2-s2.0-105049199102 (0)
11573/1775144 - 2026 -
METTL1/WDR4 Complex: A Novel Epitranscriptomic Target at the Crossroads of RNA Methylation and Drug Discovery Fabbrizi, Emanuele; Hailu, Gebremedhin Solomon; Mancini, Andrea; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 17736-17769 - issn: 1520-4804 - wos: WOS:001825578700001 (0) - scopus: 2-s2.0-105047215837 (0)
11573/1775148 - 2026 -
Deubiquitinase-targeting chimeras (DUBTACs). A game-changing approach for targeted protein stabilization in drug discovery Hailu, Gebremedhin Solomon; Fabbrizi, Emanuele; Mancini, Andrea; Fiorentino, Francesco; Mai, Antonello; Rotili, Dante - 01g Articolo di rassegna (Review)
rivista: DRUG DISCOVERY TODAY (Amsterdam: Elsevier) pp. 1-20 - issn: 1878-5832 - wos: WOS:001861197500001 (0) - scopus: 2-s2.0-105048164104 (0)
11573/1775150 - 2026 -
Systematic structure–activity relationship investigation on novel 5-alkyl-6-benzyl-2-{[(methylthio/phenylthio)alkyl]thio}-pyrimidin-4(3H)-ones endowed with potent anti-hiv-1 activity Hailu, Gebremedhin Solomon; Degtyarenko, Egor; Fabbrizi, Emanuele; Golovina, Anastasia; Voronkov, Andrey; Mancini, Andrea; Nawrozkij, Maxim B.; Chernyshov, Vladimir; Bavagnoli, Laura; Bianchi, Elena; Astolfi, Roberta; Ragno, Rino; Esté, José A.; Crespan, Emmanuele; Fiorentino, Francesco; Ivanov, Roman; Mai, Antonello; Rotili, Dante - 01a Articolo in rivista
rivista: ACS OMEGA (Washington, D.C. : American Chemical Society, 2016-) pp. 1-18 - issn: 2470-1343 - wos: WOS:001877209400001 (0) - scopus: (0)