VALENTINA NOEMI MADIA

PhD Graduate

PhD program:: XXIX



Thesis title: Pyrrolyl derivatives as novel anti-hiv-1 agents


Research products

11573/1697149 - 2023 - New blood-brain-barrier permeable compounds as Naegleria Fowleri CYP51 inhibitors.
Arpacioglu, M.; Madia, V. N.; Ialongo, D.; Patacchini, E.; Messore, A.; Tudino, V.; Sharma, V.; Nguyen, J.; Debnath, A.; Podust, L.; Palenca, I.; Basili Franzin, S.; Seguella, L.; Esposito, G.; Petrucci, R.; Di Matteo, P.; Bortolami, M.; Scipione, L.; Costi, R.; Di Santo, R. - 04f Poster
conference: XXVIII edition of the National Meeting on Medicinal Chemistry (Chieti; Italy)
book: XXVIII edition of the National Meeting on Medicinal Chemistry - ()

11573/1697156 - 2023 - Novel nsp13 inhibitors capable of blocking viral replication of SARS-CoV-2.
Arpacioglu, M.; Madia, V. N.; Messore, A.; Patacchini, E.; Ialongo, D.; Tudino, V.; Scipione, L.; Corona, A.; Esposito, F.; Artico, M.; Amatore, D.; Faggioni, G.; De Santis, R.; Lista, F.; Tramontano, E.; Costi, R.; Di Santo, R. - 04f Poster
conference: ESMEC 2023 - European School of Medicinal Chemistry – 42nd Edition (Urbino; Italy)
book: ESMEC 2023 - European School of Medicinal Chemistry – 42nd Edition - ()

11573/1686714 - 2023 - Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication
Corona, Angela; Madia, Valentina Noemi; De Santis, Riccardo; Manelfi, Candida; Emmolo, Roberta; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Amatore, Donatella; Faggioni, Giovanni; Artico, Marco; Iaconis, Daniela; Talarico, Carmine; Di Santo, Roberto; Lista, Florigio; Costi, Roberta; Tramontano, Enzo - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH (Amsterdam: Elsevier Science) pp. - - issn: 1872-9096 - wos: WOS:001062175600001 (0) - scopus: 2-s2.0-85167598331 (0)

11573/1686713 - 2023 - Effects of modified glucosamine on the chondrogenic potential of circulating stem cells under experimental inflammation
Gasparella, Marco; Cenzi, Carola; Piccione, Monica; Madia, Valentina Noemi; Di Santo, Roberto; Tudino, Valeria; Artico, Marco; Taurone, Samanta; De Ponte, Chiara; Costi, Roberta; Di Liddo, Rosa - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001020920600001 (0) - scopus: 2-s2.0-85163945199 (0)

11573/1697165 - 2023 - Aminopyrimidine derivatives as new protein kinase inhibitors endowed with anticancer activity.
Ialongo, D.; Madia, V. N.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Scarpa, S.; Rauh, D; Di Santo, R.; Costi, R. - 04f Poster
conference: 10th EFMC Young Medicinal Chemists' Symposium (Zagreb; Croatia.)
book: 10th EFMC Young Medicinal Chemists' Symposium - ()

11573/1697174 - 2023 - Pyrimidine-based compounds as new promising protein kinase inhibitors for cancer treatment.
Ialongo, D.; Madia, V. N.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Scarpa, S.; Rauh, D; Di Santo, R.; Costi, R. - 04f Poster
conference: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (Zagreb; Croatia.)
book: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - ()

11573/1697175 - 2023 - Diketo acid heterocyclic derivatives as new SARS-CoV-2 nsp13 inhibitors blocking viral replication.
Ialongo, D.; Madia, V. N.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Tudino, V.; Scipione, L.; Corona, A.; Esposito, F.; Artico, M.; Amatore, D.; Faggioni, G.; De Santis, R.; Lista, F.; Tramontano, E.; Costi, R.; Di Santo, R. - 04f Poster
conference: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (Zagreb; Croatia.)
book: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - ()

11573/1697147 - 2023 - Identification of novel aminopyrimidine derivatives as protein kinase inhibitors blocking cell growth.
Ialongo, Davide; Madia, Valentina Noemi; Messore, Antonella; Patacchini, Elisa; Arpacioglu, Merve; Scipione, Luigi; Scarpa, S.; Rauh, D.; Di Santo, R.; Costi, R. - 04f Poster
conference: XXVIII edition of the National Meeting on Medicinal Chemistry (Chieti; Italy)
book: XXVIII edition of the National Meeting on Medicinal Chemistry - ()

11573/1697162 - 2023 - New diketo acid derivatives as dual SARS-CoV-2 nsp13 inhibitors active against viral replication.
Ialongo, Davide; Madia, Valentina Noemi; Messore, Antonella; Patacchini, Elisa; Arpacioglu, Merve; Tudino, Valeria; Scipione, Luigi; Corona, Angela; Esposito, Francesca; Artico, Marco; Amatore, Donatella; Faggioni, Giovanni; De Santis, Riccardo; Lista, Florigio; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto - 04f Poster
conference: 10th EFMC Young Medicinal Chemists' Symposium (Zagreb; Croatia.)
book: 10th EFMC Young Medicinal Chemists' Symposium - ()

11573/1668131 - 2023 - Pyrrolyl and indolyl α-γ-diketo acid derivatives acting as selective inhibitors of human carbonic anhydrases IX and XII
Ialongo, Davide; Messore, Antonella; Madia, Valentina Noemi; Tudino, Valeria; Nocentini, Alessio; Gratteri, Paola; Giovannuzzi, Simone; Supuran, Claudiu T.; Nicolai, Alice; Scarpa, Susanna; Taurone, Samanta; Camarda, Michele; Artico, Marco; Papa, Veronica; Saccoliti, Francesco; Scipione, Luigi; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000941695000001 (0) - scopus: 2-s2.0-85148943598 (0)

11573/1684012 - 2023 - Synergistic Effects of Caffeine in Combination with Conventional Drugs: Perspectives of a Drug That Never Ages
Ialongo, Davide; Tudino, Valeria; Arpacioglu, Merve; Messore, Antonella; Patacchini, Elisa; Costi, Roberta; Di Santo, Roberto; Madia, Valentina Noemi - 01g Articolo di rassegna (Review)
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 730- - issn: 1424-8247 - wos: WOS:000997931100001 (2) - scopus: 2-s2.0-85160675541 (2)

11573/1678807 - 2023 - Plants and Small Molecules: An Up-and-Coming Synergy
Lepri, A.; Longo, C.; Messore, A.; Kazmi, H.; Madia, V. N.; Di Santo, R.; Costi, R.; Vittorioso, P. - 01g Articolo di rassegna (Review)
paper: PLANTS (Basel: MDPI) pp. - - issn: 2223-7747 - wos: WOS:000977210900001 (2) - scopus: 2-s2.0-85156214656 (1)

11573/1697142 - 2023 - Discovery of new small molecules as anti-SARS-CoV-2 agents inhibiting ACE2-spike binding.
Madia, V. N.; Ialongo, D.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Di Santo, R.; Costi, R. - 04f Poster
conference: XXVIII edition of the National Meeting on Medicinal Chemistry (Chieti; Italy)
book: XXVIII edition of the National Meeting on Medicinal Chemistry - ()

11573/1697168 - 2023 - Dual HIV-1 integrase catalytic site and integrase-RNA interaction inhibitors.
Madia, V. N.; Ialongo, D.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Kvaratskhelia, M.; Di Santo, R.; Costi, R. - 04f Poster
conference: 10th EFMC Young Medicinal Chemists' Symposium (Zagreb; Croatia.)
book: 10th EFMC Young Medicinal Chemists' Symposium - ()

11573/1697179 - 2023 - Quinolinonyl derivatives as dual inhibitors of the HIV-1 integrase catalytic site and integrase-RNA interactions.
Madia, V. N.; Ialongo, D.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Kvaratskhelia, M.; Di Santo, R.; Costi, R. - 04f Poster
conference: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (Zagreb; Croatia.)
book: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - ()

11573/1697181 - 2023 - Design and synthesis of brain permeable anti-Naegleria fowleri agents targeting CYP51 for primary amoebic meningoencephalitis treatment.
Madia, V. N.; Ialongo, D.; Messore, A.; Patacchini, E.; Arpacioglu, M.; Tudino, V.; Sharma, V.; Nguyen, J.; Debnath, A.; Podust, L.; Palenca, I.; Basili Franzin, S.; Seguella, L.; Esposito, G.; Petrucci, R.; Di Matteo, P.; Bortolami, M.; Scipione, L.; Costi, R.; Di Santo, R. - 04f Poster
conference: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (Zagreb; Croatia.)
book: IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry - ()

11573/1697153 - 2023 - Small molecule derivatives as dual inhibitors of SARS-CoV-2 nsp13 blocking viral replication.
Madia, V. N.; Ialongo, D.; Patacchini, E.; Arpacioglu, M.; Messore, A.; Tramontano, E.; De Santis, R.; Lista, F.; Costi, R.; Di Santo, R. - 04f Poster
conference: 3rd Synthesis in Drug Discovery and Development (Virtual meeting)
book: 3rd Synthesis in Drug Discovery and Development - ()

11573/1697146 - 2023 - Discovery of quinolinonyl derivatives as anti-HIV-1 inhibitors endowed with an innovative mechanism of action.
Madia, Valentina Noemi; Ialongo, Davide; Messore, Antonella; Patacchini, Elisa; Arpacioglu, Merve; Scipione, Luigi; Di Santo, Roberto; And Costi, Roberta. - 04f Poster
conference: XXVIII edition of the National Meeting on Medicinal Chemistry (Chieti; Italy)
book: XXVIII edition of the National Meeting on Medicinal Chemistry - ()

11573/1663401 - 2023 - Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site
Madia, Valentina Noemi; Ialongo, Davide; Patacchini, Elisa; Exertier, Cécile; Antonelli, Lorenzo; Colotti, Gianni; Messore, Antonella; Tudino, Valeria; Saccoliti, Francesco; Scipione, Luigi; Ilari, Andrea; Costi, Roberta; Di Santo, Roberto Di - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 338- - issn: 1420-3049 - wos: WOS:000909976300001 (0) - scopus: 2-s2.0-85145692255 (0)

11573/1697172 - 2023 - Miconazole-like compounds as brain permeable anti-Naegleria Fowleri agents targeting CYP51.
Madia, Valentina Noemi; Ialongo, Davide; Patacchini, Elisa; Messore, Antonella; Arpacioglu, Merve; Tudino, V.; Sharma, V.; Nguyen, J.; Debnath, A.; Podust, L.; Palenca, I.; Basili Franzin, S.; Seguella, L.; Esposito, G.; Petrucci, R.; Di Matteo, P.; Bortolami, M.; Scipione, L.; Costi, Roberta; Di Santo, Roberto. - 04f Poster
conference: 10th EFMC Young Medicinal Chemists' Symposium (Zagreb; Croatia.)
book: 10th EFMC Young Medicinal Chemists' Symposium - ()

11573/1687531 - 2023 - Role of a Novel Heparanase Inhibitor on the Balance between Apoptosis and Autophagy in U87 Human Glioblastoma Cells
Manganelli, V.; Misasi, R.; Riitano, G.; Capozzi, A.; Mattei, V.; Caglar, T. R.; Ialongo, D.; Madia, V. N.; Messore, A.; Costi, R.; Di Santo, R.; Sorice, M.; Garofalo, T. - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 1-14 - issn: 2073-4409 - wos: WOS:001038054000001 (0) - scopus: 2-s2.0-85165884087 (0)

11573/1697140 - 2023 - Design and synthesis of tetrahydro-β-carbolines derivatives as PDIA inhibitors.
Messore, A.; Madia, V. N.; Ialongo, D.; Patacchini, E.; Arpacioglu, M.; Scipione, L.; Altieri, F.; Paglia, G.; Meschiari, G.; Di Santo, R.; Costi, R. - 04f Poster
conference: XXVIII edition of the National Meeting on Medicinal Chemistry (Chieti; Italy)
book: XXVIII edition of the National Meeting on Medicinal Chemistry - ()

11573/1697150 - 2023 - From Iloperidone to new Sigma1 agonists: a structure-based approach for Huntington's disease treatment.
Patacchini, Elisa; Madia, Valentina Noemi; Ialongo, Davide; Messore, Antonella; Ilari, Andrea; Cosconati, Sandro; Di Santo, Roberto; Costi, Roberta. - 04f Poster
conference: ESMEC 2023 - European School of Medicinal Chemistry – 42nd Edition (Urbino; Italy)
book: ESMEC 2023 - European School of Medicinal Chemistry – 42nd Edition - ()

11573/1696092 - 2023 - Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors
Sharma, Vandna; Madia, Valentina Noemi; Tudino, Valeria; V Nguyen, Jennifer; Debnath, Anjan; Messore, Antonella; Ialongo, Davide; Patacchini, Elisa; Palenca, Irene; Basili Franzin, Silvia; Seguella, Luisa; Esposito, Giuseppe; Petrucci, Rita; Di Matteo, Paola; Bortolami, Martina; Saccoliti, Francesco; Di Santo, Roberto; Scipione, Luigi; Costi, Roberta; M Podust, Larissa - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 17059-17073 - issn: 0022-2623 - wos: WOS:001134079100001 (0) - scopus: 2-s2.0-85180091142 (0)

11573/1638218 - 2022 - Design, synthesis, and In vitro, in silico and in cellulo evaluation of new Pyrimidine and Pyridine amide and Carbamate derivatives as multi-functional Cholinesterase Inhibitors
Bortolami, Martina; Pandolfi, Fabiana; Tudino, Valeria; Messore, Antonella; Madia, Valentina Noemi; De Vita, Daniela; Di Santo, Roberto; Costi, Roberta; Romeo, Isabella; Alcaro, Stefano; Colone, Marisa; Stringaro, Annarita; Espargaró, Alba; Sabatè, Raimon; Scipione, Luigi - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. 1-31 - issn: 1424-8247 - wos: WOS:000818156100001 (3) - scopus: 2-s2.0-85134396743 (2)

11573/1654141 - 2022 - New Inhibitors of the human p300/CBP acetyltransferase are selectively active against the Arabidopsis HAC proteins
Longo, Chiara; Lepri, Andrea; Paciolla, Andrea; Messore, Antonella; De Vita, Daniela; Bonaccorsi Di Patti, Maria Carmela; Amadei, Matteo; Madia, Valentina Noemi; Ialongo, Davide; Di Santo, Roberto; Costi, Roberta; Vittorioso, Paola - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-18 - issn: 1422-0067 - wos: WOS:000859422800001 (3) - scopus: 2-s2.0-85138734584 (3)

11573/1648549 - 2022 - Ultrastructural damages to H1N1 influenza virus caused by vapor essential oils
Madia, Valentina Noemi; Toscanelli, Walter; De Vita, Daniela; De Angelis, Marta; Messore, Antonella; Ialongo, Davide; Scipione, Luigi; Tudino, Valeria; D'auria, Felicia Diodata; Di Santo, Roberto; Garzoli, Stefania; Stringaro, Annarita; Colone, Marisa; Marchetti, Magda; Superti, Fabiana; Nencioni, Lucia; Costi, Roberta - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-14 - issn: 1420-3049 - wos: WOS:000816243700001 (5) - scopus: 2-s2.0-85131746075 (5)

11573/1623281 - 2022 - Oxidative stress and visual system a review
Taurone, S.; Ralli, M.; Artico, M.; Madia, V. N.; Scarpa, S.; Nottola, S. A.; Maconi, A.; Betti, M.; Familiari, P.; Nebbioso, M.; Costi, R.; Micera, A. - 01g Articolo di rassegna (Review)
paper: EXCLI JOURNAL (Mainz: EXCLI Journal Business Office c/o 2nd Medical Department, University of Mainz.) pp. 544-553 - issn: 1611-2156 - wos: WOS:000766811300001 (8) - scopus: 2-s2.0-85125850235 (10)

11573/1564954 - 2021 - Toxicological aspects of cannabinoid, pesticide and metal levels detected in light Cannabis inflorescences grown in Italy
Amendola, G.; Bocca, B.; Picardo, V.; Pelosi, P.; Battistini, B.; Ruggieri, F.; Attard Barbini, D.; De Vita, D.; Madia, V. N.; Messore, A.; Di Santo, R.; Costi, R. - 01a Articolo in rivista
paper: FOOD AND CHEMICAL TOXICOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. - - issn: 0278-6915 - wos: WOS:000696988600002 (5) - scopus: 2-s2.0-85112006002 (7)

11573/1490818 - 2021 - Acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease–a patent review (2016–present)
Bortolami, M.; Rocco, D.; Messore, A.; Di Santo, R.; Costi, R.; Madia, V. N.; Scipione, L.; Pandolfi, F. - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 1-22 - issn: 1354-3776 - wos: WOS:000607685400001 (28) - scopus: 2-s2.0-85099470810 (27)

11573/1584588 - 2021 - New pyrimidine and pyridine derivatives as multitarget cholinesterase inhibitors. Design, synthesis, and in vitro and in cellulo evaluation
Bortolami, Martina; Pandolfi, Fabiana; Tudino, Valeria; Messore, Antonella; Madia, Valentina Noemi; De Vita, Daniela; Di Santo, Roberto; Costi, Roberta; Romeo, Isabella; Alcaro, Stefano; Colone, Marisa; Stringaro, Annarita; Espargaró, Alba; Sabatè, Raimon; Scipione, Luigi - 01a Articolo in rivista
paper: ACS CHEMICAL NEUROSCIENCE (Washington, D.C. : American Chemical Society) pp. 4090-4112 - issn: 1948-7193 - wos: WOS:000715842900011 (10) - scopus: 2-s2.0-85118138783 (12)

11573/1404920 - 2021 - Towards a new application of amaranth seed oil as an agent against Candida albicans
De Vita, Daniela; Messore, Antonella; Toniolo, Chiara; Frezza, Claudio; Scipione, Luigi; Bertea, Cinzia Margherita; Micera, Marco; Di Sarno, Veronica; Madia, Valentina Noemi; Pindinello, Ivano; Roscilli, Patrizia; Botto, Alfonso; Simonetti, Giovanna; Orekhova, Anastasia; Manfredini, Stefano; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: NATURAL PRODUCT RESEARCH (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 4621-4626 - issn: 1478-6419 - wos: WOS:000500457200001 (14) - scopus: 2-s2.0-85075913942 (5)

11573/1540215 - 2021 - Investigation of Commiphora myrrha (Nees) Engl. oil and its main components for antiviral activity
Madia, Valentina Noemi; De Angelis, Marta; De Vita, Daniela; Messore, Antonella; De Leo, Alessandro; Ialongo, Davide; Tudino, Valeria; Saccoliti, Francesco; De Chiara, Giovanna; Garzoli, Stefania; Scipione, Luigi; Palamara, Anna Teresa; Di Santo, Roberto; Nencioni, Lucia; Costi, Roberta - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000634055800001 (15) - scopus: 2-s2.0-85102987115 (18)

11573/1564144 - 2021 - Recent advances in recovery of lycopene from tomato waste. A potent antioxidant with endless benefits
Madia, Valentina Noemi; De Vita, Daniela; Ialongo, Davide; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; Di Santo, Roberto; Costi, Roberta; Messore, Antonella - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-18 - issn: 1420-3049 - wos: WOS:000682223800001 (33) - scopus: 2-s2.0-85111602310 (40)

11573/1540619 - 2021 - Analytical characterization of an inulin-type fructooligosaccharide from root-tubers of Asphodelus ramosus L
Madia, Valentina Noemi; De Vita, Daniela; Messore, Antonella; Toniolo, Chiara; Tudino, Valeria; De Leo, Alessandro; Pindinello, Ivano; Ialongo, Davide; Saccoliti, Francesco; D'ursi, Anna Maria; Grimaldi, Manuela; Ceccobelli, Pietro; Scipione, Luigi; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000634075100001 (4) - scopus: 2-s2.0-85103099178 (3)

11573/1565318 - 2021 - Small-molecule inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H function. Challenges and recent developments
Madia, Valentina Noemi; Messore, Antonella; De Leo, Alessandro; Tudino, Valeria; Pindinello, Ivano; Saccoliti, Francesco; De Vita, Daniela; Scipione, Luigi; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: CURRENT MEDICINAL CHEMISTRY (Hilversum: Bentham Science Publishers) pp. 1-33 - issn: 1875-533X - wos: WOS:000696992000004 (3) - scopus: 2-s2.0-85115249511 (4)

11573/1493998 - 2021 - Design, synthesis and biological evaluation of new pyrimidine derivatives as anticancer agents
Madia, Valentina Noemi; Nicolai, Alice; Messore, Antonella; De Leo, Alessandro; Ialongo, Davide; Tudino, Valeria; Saccoliti, Francesco; De Vita, Daniela; Scipione, Luigi; Artico, Marco; Taurone, Samanta; Taglieri, Ludovica; Di Santo, Roberto; Scarpa, Susanna; Costi, Roberta - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000615455300001 (11) - scopus: 2-s2.0-85101195321 (12)

11573/1556284 - 2021 - Quinolinonyl non-diketo acid derivatives as Inhibitors of HIV-1 ribonuclease H and polymerase functions of reverse transcriptase
Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8579-8598 - issn: 0022-2623 - wos: WOS:000668340800039 (9) - scopus: 2-s2.0-85108607601 (8)

11573/1553152 - 2021 - Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines
Nicolai, Alice; Madia, Valentina Noemi; Messore, Antonella; De Vita, Daniela; De Leo, Alessandro; Ialongo, Davide; Tudino, Valeria; Tortorella, Elisabetta; Scipione, Luigi; Taurone, Samanta; Pergolizzi, Tiziano; Artico, Marco; Di Santo, Roberto; Costi, Roberta; Scarpa, Susanna - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000666329400001 (6) - scopus: 2-s2.0-85110773299 (6)

11573/1408850 - 2020 - Pyrrolyl pyrazoles as non-diketo acid inhibitors of the HIV-1 ribonuclease H function of reverse transcriptase
Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 798-805 - issn: 1948-5875 - wos: WOS:000535281200029 (22) - scopus: 2-s2.0-85086659986 (23)

11573/1274892 - 2020 - Discovery of a pyrimidine compound endowed with antitumor activity
Taglieri, Ludovica; Saccoliti, Francesco; Nicolai, Alice; Peruzzi, Giovanna; Madia, Valentina Noemi; Tudino, Valeria; Messore, Antonella; Di Santo, Roberto; Artico, Marco; Taurone, Samanta; Salvati, Maurizio; Costi, Roberta; Scarpa, Susanna - 01a Articolo in rivista
paper: INVESTIGATIONAL NEW DRUGS (attuale: -SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ -Kluwer Academic Publishers / Massachusetts:PO Box 358, Accord Station:Hingham, MA 02018:(617)871-6600) pp. 39-49 - issn: 0167-6997 - wos: WOS:000512107200005 (11) - scopus: 2-s2.0-85063345760 (11)

11573/1336764 - 2019 - Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism
Colotti, G.; Saccoliti, F.; Gramiccia, M.; Di Muccio, T.; Prakash, J.; Yadav, S.; Dubey, V. K.; Vistoli, G.; Battista, T.; Mocci, S.; Fiorillo, A.; Bibi, Aasia; Madia, V. N.; Messore, A.; Costi, R.; Di Santo, R.; Ilari, A. - 01a Articolo in rivista
paper: AMINO ACIDS (Wien: Springer Verlag) pp. - - issn: 0939-4451 - wos: WOS:000519385700013 (10) - scopus: 2-s2.0-85065106515 (11)

11573/1285185 - 2019 - Comparison of different methods for the extraction of cannabinoids from cannabis
De Vita, D.; Madia, V. N.; Tudino, V.; Saccoliti, F.; De Leo, A.; Messore, A.; Roscilli, P.; Botto, A.; Pindinello, I.; Santilli, G.; Scipione, L.; Costi, R.; Di Santo, R. - 01a Articolo in rivista
paper: NATURAL PRODUCT RESEARCH (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1-7 - issn: 1478-6419 - wos: WOS:000575920700013 (32) - scopus: 2-s2.0-85065155862 (36)

11573/1205976 - 2019 - In vitro antiviral activity of new oxazoline derivatives as potent poliovirus inhibitors
Madia, Valentina Noemi; Messore, Antonella; Pescatori, Luca; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; Fiore, Lucia; Rhoden, Eric; Manetti, Fabrizio; Oberste, M Steven; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 798-810 - issn: 0022-2623 - wos: WOS:000457067600026 (8) - scopus: 2-s2.0-85060542889 (10)

11573/1405464 - 2019 - Tegaserod for the treatment of Irritable Bowel syndrome
Madia, Valentina Noemi; Messore, Antonella; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; De Vita, Daniela; Bortolami, Martina; Scipione, Luigi; Pindinello, Ivano; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: ANTI-INFLAMMATORY & ANTI-ALLERGY AGENTS IN MEDICINAL CHEMISTRY (Hilversum : Bentham Science Publsihers) pp. 1-28 - issn: 1871-5230 - wos: (0) - scopus: 2-s2.0-85083912835 (0)

11573/1321741 - 2019 - Inhibition of Polycomb Repressive Complex2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings
Ruta, Veronica; Longo, Chiara; Boccaccini, Alessandra; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; Di Santo, Roberto; Lorrai, Riccardo; Dello Ioio, Raffaele; Sabatini, Sabrina; Costi, Roberta; Costantino, Paolo; Vittorioso, Paola - 01a Articolo in rivista
paper: BMC PLANT BIOLOGY (London: BioMed Central.MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB) pp. - - issn: 1471-2229 - wos: WOS:000490716900003 (12) - scopus: 2-s2.0-85073428390 (12)

11573/1222183 - 2019 - Design, synthesis, and biological evaluation of new 1-(aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents
Saccoliti, Francesco; Madia, Valentina Noemi; Tudino, Valeria; De Leo, Alessandro; Pescatori, Luca; Messore, Antonella; De Vita, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; Mäser, Pascal; Calvet Alvarez, Claudia Magalhaes; Jennings, Gareth K; Podust, Larissa M; Pepe, Giacomo; Cirilli, Roberto; Faggi, Cristina; Di Marco, Annalise; Battista, Maria Rosaria; Summa, Vincenzo; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1330-1347 - issn: 0022-2623 - wos: WOS:000459223600016 (23) - scopus: 2-s2.0-85061636363 (26)

11573/1176836 - 2018 - Novel benzazole derivatives endowed with potent antiheparanase activity
Madia, Valentina Noemi; Messore, Antonella; Pescatori, Luca; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Bortolami, Martina; Scipione, Luigi; Costi, Roberta; Rivara, Silvia; Scalvini, Laura; Mor, Marco; Fosca Ferrara, Fabiana; Pavoni, Emiliano; Roscilli, Giuseppe; Cassinelli, Giuliana; M Milazzo, Ferdinando; Battistuzzi, Gianfranco; Di Santo, Roberto; Giannin, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6918-6936 - issn: 0022-2623 - wos: WOS:000441484300030 (28) - scopus: 2-s2.0-85050088127 (28)

11573/1221546 - 2018 - Novel symmetrical benzazolyl derivatives endowed with potent anti-heparanase activity
Messore, Antonella; Madia, Valentina Noemi; Pescatori, Luca; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Bortolami, Martina; De Vita, Daniela; Scipione, Luigi; Pepi, Federico; Costi, Roberta; Rivara, Silvia; Scalvini, Laura; Mor, Marco; Ferrara, Fabiana Fosca; Pavoni, Emiliano; Roscilli, Giuseppe; Cassinelli, Giuliana; Milazzo, Ferdinando M; Battistuzzi, Gianfranco; Di Santo, Roberto; Giannini, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10834-10859 - issn: 0022-2623 - wos: WOS:000453488200031 (17) - scopus: 2-s2.0-85058215116 (16)

11573/1174521 - 2018 - Selective inhibition of the PRC2 methyltransferase activity suppresses trimethylation of H3K27 in Arabidopsis seeds
Ruta, Veronica; Boccaccini, Alessandra; Longo, Chiara; Madia, Valentina Noemi; Tudino, Valeria; Costi, Roberta; Costantino, Paolo; Vittorioso, Paola - 04f Poster
conference: International Plant and Molecular Biology 2018- IPMB2018 (Montpellier)
book: nessuna - ()

11573/1176720 - 2018 - Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents
Saccoliti, Francesco; Madia, Valentina Noemi; Tudino, Valeria; De Leo, Alessandro; Pescatori, Luca; Messore, Antonella; De Vita, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; Mäser, Pascal; Magalhaes Calvet, Claudia; K Jennings, Gareth; M Podust, Larissa; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 53-60 - issn: 0223-5234 - wos: WOS:000443663200005 (16) - scopus: 2-s2.0-85049312582 (20)

11573/1192249 - 2017 - Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase
Madia, Valentina Noemi; Benedetti, Rosaria; Letizia Barreca, Maria; Ngo, Liza; Pescatori, Luca; Messore, Antonella; Pupo, Giovanni; Saccoliti, Francesco; Valente, Sergio; Mai, Antonello; Scipione, Luigi; George Zheng, Yujun; Tintori, Cristina; Botta, Maurizio; Cecchetti, Violetta; Altucci, Lucia; Di Santo, Roberto; Costi, Roberta - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 1359-1368 - issn: 1860-7187 - wos: WOS:000429592300014 (10) - scopus: 2-s2.0-85017448829 (9)

11573/929856 - 2017 - Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives
Saccoliti, Francesco; Angiulli, Gabriella; Pupo, Giovanni; Pescatori, Luca; Madia, Valentina Noemi; Messore, Antonella; Colotti, Gianni; Fiorillo, Annarita; Scipione, Luigi; Gramiccia, Marina; Di Muccio, Trentina; Di Santo, Roberto; Costi, Roberta; Ilari, Andrea - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 304-310 - issn: 1475-6366 - wos: WOS:000392591100025 (46) - scopus: 2-s2.0-85013797723 (48)

11573/910116 - 2016 - New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H
Corona, A; Di Leva, Fs; Rigogliuso, G; Pescatori, Luca; Madia, Valentina Noemi; Subra, F; Delelis, O; Esposito, F; Cadeddu, M; Costi, Roberta; Cosconati, S; Novellino, E; Di Santo, Roberto; Tramontano, E. - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH ([Amsterdam]; [New York]: Elsevier/North-Holland, [c1981]-) pp. 236-243 - issn: 0166-3542 - wos: WOS:000386983800026 (35) - scopus: 2-s2.0-84989205085 (34)

11573/852938 - 2015 - Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75
Cuzzucoli Crucitti, G.; Pescatori, L.; Messore, A.; Madia, V. N.; Pupo, G.; Saccoliti, F; Scipione, L; Tortorella, S.; Di Leva, F. S; Cosconati, S; Novellino, E; Debyser, Z; Christ, F; Costi, R; Di Santo, R - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 288-294 - issn: 0223-5234 - wos: WOS:000360771900026 (16) - scopus: 2-s2.0-84936802596 (16)

11573/895359 - 2015 - Structure−activity relationship of pyrrolyl diketo acid derivatives as dual Inhibitors of HIV‑1 integrase and reverse transcriptase ribonuclease H domain
Cuzzucoli Crucitti, Giuliana; Métifiot, Mathieu; Pescatori, Luca; Messore, Antonella; Madia, Valentina Noemi; Pupo, Giovanni; Saccoliti, Francesco; Scipione, Luigi; Tortorella, Silvano; Esposito, Francesca; Corona, Angela; Cadeddu, Marta; Marchand, Christophe; Pommier, Yves; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1915-1928 - issn: 0022-2623 - wos: WOS:000351186700021 (72) - scopus: 2-s2.0-84923882396 (76)

11573/787196 - 2015 - N‑substituted quinolinonyl diketo acid derivatives as HIV integrase strand transfer inhibitors and their activity against RNase H function of reverse transcriptase
Pescatori, Luca; Metifiot, Mathieu; Chung, Suhman; Masoaka, Takashi; Crucitti Cuzzucoli, Giuliana; Messore, Antonella; Pupo, Giovanni; Madia, Valentina Noemi; Saccoliti, Francesco; Scipione, Luigi; Tortorella, Silvano; Di Leva, Francesco Saverio; Cosconati, Sandro; Marinelli, Luciana; Novellino, Ettore; Le Grice, Stuart F. J.; Pommier, Yves; Marchand, Christophe; Costi, Roberta; Di Santo, Roberto - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4610-4623 - issn: 0022-2623 - wos: WOS:000356316600015 (40) - scopus: 2-s2.0-84935877076 (44)

11573/559331 - 2014 - Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase
Costi, Roberta; Mathieu, Metifiot; Suhman, Chung; Cuzzucoli Crucitti, Giuliana; Kasthuraiah, Maddali; Pescatori, Luca; Messore, Antonella; Madia, Valentina Noemi; Giovanni, Pupo; Scipione, Luigi; Tortorella, Silvano; Francesco Saverio Di, Leva; Sandro, Cosconati; Luciana, Marinelli; Ettore, Novellino; Stuart F: J., Le Grice; Angela, Corona; Yves, Pommier; Christophe, Marchand; Di Santo, Roberto - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 3223-3234 - issn: 1520-4804 - wos: WOS:000335113900005 (52) - scopus: 2-s2.0-84899554749 (56)

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