VALENTINA NACCARATO

PhD Graduate

PhD program:: XXXII


supervisor: Prof. Romano Silvestri
advisor: Prof. Romano Silvestri
co-supervisor: Prof. Romano Silvestri

Thesis title: New tubulin and NHERF1 targeting anticancer agents


Research products

11573/1223718 - 2019 - Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents
Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 499-503 - issn: 1948-5875 - wos: WOS:000464767700019 (14) - scopus: 2-s2.0-85064264813 (14)

11573/1223723 - 2019 - Towards modern anticancer agents that interact with tubulin
La Regina, G.; Coluccia, A.; Naccarato, V.; Silvestri, R. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (Amsterdam Netherlands: Elsevier BV) pp. 58-68 - issn: 0928-0987 - wos: WOS:000460399800006 (41) - scopus: 2-s2.0-85061343987 (42)

11573/1338512 - 2019 - Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Bufano, M.; Nalli, M.; Coluccia, A.; Orlando, V.; Canettieri, G.; Gianni, S.; Silvestri, R. - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()

11573/1338507 - 2019 - Small molecule inhibitors of kdm5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing JARID1B
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Nalli, M.; Coluccia, A.; Negri, R.; Silvestri, R. - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()

11573/1278679 - 2019 - New anti-cancer agents through an interaction with tubulin
La Regina, G; Coluccia, A; Naccarato, V; Silvestri, R. - 04f Poster
conference: New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours - First Working-Group Meeting (Torino (TO))
book: Abstract Book - ()

11573/1278540 - 2019 - First in class pdz1 targeting NHERF1 inhibitors as anticancer agents
La Regina, Giuseppe; Naccarato, Valentina; Puxeddu, Michela; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 12th European Workshop in Drug Design (Siena)
book: Book of Abstract - ()

11573/1266997 - 2019 - Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b
Pippa, S; Mannironi, C; Licursi, V; Bombardi, Luca; Colotti, G; Cundari, E; Mollica, A; Coluccia, A; Naccarato, V; La Regina, G; Silvestri, R; Negri, R - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000469518100098 (24) - scopus: 2-s2.0-85065652898 (25)

11573/1278549 - 2019 - Inhibition of human Norovirus replication by a novel class of oindolylarylsulfones in vitro and in zebrafish larvae
Van Dycke, Jana; Naccarato, Valentina; La Regina, Giuseppe; Mastrangelo, Eloise; Tarantino, Delia; Neyts, Johan; Silvestri, Romano; Rocha-Pereira, Joana - 04f Poster
conference: 32nd International Conference on Antiviral Research (Baltimora, Stati Uniti)
book: Program and Abstracts - ()

11573/1117718 - 2018 - New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors
La Regina, G.; Naccarato, V.; Coluccia, A.; Hamel, E.; Silvestri, R. - 04f Poster
conference: Seventh European Workshop in Drug Synthesis (Siena)
book: Seventh European Workshop in Drug Synthesis - ()

11573/1117651 - 2018 - New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors
La Regina, Giuseppe; Bai, Ruoli; Coluccia, Antonio; Naccarato, Valentina; Famiglini, Valeria; Nalli, Marianna; Masci, Domiziana; Verrico, Annalisa; Rovella, Paola; Mazzoccoli, Carmela; Da Pozzo, Eleonora; Cavallini, Chiara; Martini, Claudia; Vultaggio, Stefania; Dondio, Giulio; Varasi, Mario; Mercurio, Ciro; Hamel, Ernest; Lavia, Patrizia; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 283-297 - issn: 0223-5234 - wos: WOS:000435048900023 (31) - scopus: 2-s2.0-85046738606 (34)

11573/1170129 - 2018 - Treating chronic myeloid leukemia by inhibition of tubulin polymerization
La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Maria Luce Coluccia, Addolorata; Hamel, Ernest; Novellino, Ettore; Silvestri, Romano - 04b Atto di convegno in volume
conference: Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry (Palermo)
book: Book of Abstracts - ()

11573/1071891 - 2018 - β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
Saponaro, Concetta; Sergio, Sara; Coluccia, Antonio; De Luca, Maria; La Regina, Giuseppe; Mologni, Luca; Famiglini, Valeria; Naccarato, Valentina; Bonetti, Daniela; Gautier, Candice Natacha Anna; Gianni, Stefano; Vergara, Daniele; Salzet, Michel; Fournier, Isabelle; Bucci, Cecilia; Silvestri, Romano; Gambacorti Passerini, Carlo; Maffia, Michele; Maria Luce Coluccia, Addolorata - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3301-3316 - issn: 0950-9232 - wos: WOS:000435526600009 (18) - scopus: 2-s2.0-85044095990 (20)

11573/954246 - 2017 - 3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin
La Regina, Giuseppe; Bai, R.; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Naccarato, Valentina; Ortar, Giorgio; Mazzoccoli, Carmela; Ruggieri, V.; Agriesti, F.; Piccoli, C.; Tataranni, T.; Nalli, Marianna; Brancale, A.; Vultaggio, S.; Mercurio, C.; Varasi, M.; Saponaro, C.; Sergio, S.; Maffia, M.; Coluccia, A. M. L.; Hamel, E.; Silvestri, Romano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 521-526 - issn: 1948-5875 - wos: WOS:000401402900010 (8) - scopus: 2-s2.0-85018898332 (9)

11573/1284136 - 2017 - Inhibition of dengue virus by novel inhibitors of RNA-dependent RNA polymerase and protease activity
La Regina, Giuseppe; Famiglini, Valeria; Naccarato, Valentina; Coluccia, Antonio; Hiscott, John; Lee, Jin-Ching - 04d Abstract in atti di convegno
conference: 30th International Conference on Antiviral Research (Atlanta, Stati Uniti)
book: Program and Abstracts - ()

11573/1033456 - 2017 - 3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin
La Regina, Giuseppe; Naccarato, Valentina; Coluccia, Antonio; Maria Luce Coluccia, Addolorata; Hamel, Ernest; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()

11573/1033457 - 2017 - New pyrrole inhibitors of chronic myeloid leukemia cell growth
Naccarato, Valentina; La Regina, Giuseppe; Coluccia, Antonio; Maria Luce Coluccia, Addolorata; Hamel, Hernest; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()

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