Research: Lymph node micrometastases in HNSCC: molecular profiling of histologically negative lymph nodes for prognostic and therapeutic purposes
• PERSONAL DATA
Date and place of birth: 26/09/1997, Salerno (SA), Italy
Work address: IRCCS Regina Elena National Cancer Institute, Rome, Italy
Phone number: +39 06 52662533 e-mail address: valentina.depascale@ifo.it
• EDUCATION
2019-2021: Master Degree in Biology, University of Perugia, Perugia, Italy
2017-2019: Bachelor Degree in Biology, University of Perugia, Perugia, Italy
• RESEARCH EXPERIENCE
2023: Health Researcher, Lab. Translational Oncology Research (head Dr. Giovanni Blandino), IRCCS Regina Elena National Cancer Institute, Rome, Italy
2022: Sapienza Fellowship, Lab. Translational Oncology Research (head Dr. Giovanni Blandino), IRCCS Regina Elena National Cancer Institute, Rome, Italy
2020-2021: Master Degree Internship, Laboratory of Gastroenterology, University of Perugia, Perugia, Italy
• TECHNICAL SKILLS AND COMPETENCES
Establishment and maintenance of adherent/suspension cell cultures; Separation of mononuclear cells from BM or PB by density gradient centrifugation; Cell sorting (BD FACSMelody); Isolation and purification of nucleic acids from cells and blood (DNAs/RNAs, circulating-free DNAs/RNAs/microRNAs); PCR, RT-qPCR and digital PCR (QuantStudio3D and Absolute Q); NGS analysis (IonTorrent GeneStudio S5); Preparation of protein lysates from cell cultures; Analysis of protein expression (Western Blotting, FACS); Cytometric evaluation of MM population (BD FACSLyric), cell cycle (Acridin Orange, PI, BrdU, EdU), and apoptosis (AnnV/PI); Database Interrogation and bioinformatics.
• AWARDS
2022: Winner of Sapienza-IRE 1-year fellowship for the project NANO-COVD-TEST
• PUBLICATIONS
2023 - Detection of anti-SARS CoV-2 antibodies in human serum by means of Bloch surface waves on 1D photonic crystal biochips
2023 - It is time to improve the diagnostic workup of oropharyngeal cancer with circulating tumor HPV DNA: Systematic review and meta‐analysis