Ricerca: Targeting Notch signaling by the g-secretase inhibitor nirogacestat to counteract fibrosis onset and mainteinance in chronic skin diseases
WORK EXPERIENCES
January 2025 - present
Researcher/PhD student - Skin fibrotic disorders. Department of Genodermatosis - Ospedale Pediatrico Bambino Gesù (Rome, IT) - Scientific tutors: Dr. Giovanna Zambruno and Dr. Angelo Giuseppe Condorelli.
May 2023 - December 2024
Researcher - Gene editing technologies for the treatment of blood disorders and pediatric myelodysplasia Department of Pediatric Onco-Hematology - Ospedale Pediatrico Bambino Gesù (Rome, IT) - Tutor: Dr. Giulia Ceglie.
May 2023 - December 2023
Laboratory activities - Evidence analysis and personal identification Forensic Genetics Laboratory - University of Rome Tor Vergata (Rome, IT) - Director: Prof. Emiliano Giardina.
February 2023 - April 2023
Laboratory internship - Gene editing technologies for the treatment of USH2A mutations-mediated retinopathy Molecular Genetics Laboratory, Institute for Ophthalmic Research (Tuebingen, DE) - Tutor: Dr. Pietro De Angeli.
December 2022 - January 2023
Laboratory internship - Metabolic reprogramming in EGFR mutated NSCLC cells Laboratory of Experimental Oncology, Department of Medicine and Surgery (Parma, IT) - Tutor: Prof. Andrea Cavazzoni.
April 2021 - October 2021
Internship for Master’s degree - Laboratory of molecular (CRISPR/Cas9 based approaches) and cellular biology. Laboratory of Medical Genetics, Department of Cellular Therapies, Hematology and Laboratory Medicine, Policlinico Le Scotte (Siena, IT) -Director: Prof. Alessandra Renieri.
May 2019 - June 2019
Internship for Bachelor’s degree - Training on principal laboratory techniques. Retrovirus Center, Department of Translational Research and New Technologies in Medicine and Surgery (Pisa, IT) - Dr. Prof. Mauro Pistillo
EDUCATION
November 2024 - present
PhD in Human Biology and Medical Genetics: University of Rome “La Sapienza” (IT).
February 2023 - December 2023
Second Level Master Degree in Forensic Genetic - University of Rome Tor Vergata (Rome, IT). Dissertation title: “Evolution of personal identification - Salivary and microbial DNA analysis”.
October 2022
Professional qualification exam, University of Bari (IT).
September 2019 - October 2021
Master’s Degree: Scienze Biomolecolari, Genomiche e Cellulari, University of Parma (IT). Dissertation title: “Application of CRISPR/Cas9 technology for the treatment of intellectual disability associated with IQSEC2”.
September 2016 - October 2019
Bachelor’s Degree: Scienze Biologiche, University of Pisa (IT). Dissertation title: “Anomalies in nerve conduction: Guillain-Barré Syndrome“.