STEFANO GIANNI

Professore ordinario

email: stefano.gianni@uniroma1.it
telefono: 067886799



Stefano GIANNI
Curriculum Vitae

Parte I – Informazioni Generali

Nome Cognome Stefano GIANNI
Data di nascita 27 Gennaio 1976
Luogo di nascita Rome
Cittadinanza Italiana
Indirizzo Via Tommaso da Celano 94, 00179, Roma, Italia
Telefono 338-8964614
E-mail stefano.gianni@uniroma1.it
Lingue Italian (madre lingua), English (fluente)
ORCID 0000-0003-1653-1925

Parte II – Titoli di Studio


Laurea Dic 1999 Sapienza Università di Roma Laurea in Biologia
PhD Marzo 2003 Sapienza Università di Roma PhD in Biochimica
Pre-doctorate training Ott 2001 – Mazo 2003 Medical Research Council – Centre for Protein Engineering, Cambridge (UK) Visiting Scientist
Post-doctorate training Mar 2003 – Genn 2004 Medical Research Council – Centre for Protein Engineering, Cambridge (UK) Visiting Scientist
Post-doctorate training Mar 2004 – Mag 2005 Sapienza University of Rome Assegnista di Ricerca
Post-doctorate training Giu 2005 – Dic 2005 Sapienza Università di Roma Borsista Istituto Pasteur –Fondazione Cenci Bolognetti (borse di studio per l’Italia per il rientro dall’estero)


Parte III – Incarichi

IIIA – Incarichi Accademici


Dic 2005 Dic 2012 CNR – Consiglio Nazionale delle Ricerche – Istituto di Biologia e Patologia Molecolari, Roma, Italia Ricercatore
Dic 2012 Ott 2016 Sapienza Università di Roma Professore Associato
Maggio 2013 Lug 2016 University of Cambridge, Dept. of Chemistry, Cambridge (UK) Visiting Professor
Nov 2016 oggi Sapienza Università di Roma Professore Ordinario


IIIB – Altro Incarichi


Lug 2013 oggi Sapienza Università di Roma – Facoltà di Farmacia e Medicina – Corso di Laurea in Scienze Farmaceutiche Applicate Commissione Pratiche studenti
2015 date Sapienza Università di Roma – Facoltà di Farmacia e Medicina – Corsi di Laurea in: Scienze Farmaceutiche Applicate; Inform. scientifica sul farmaco; Scienze e Tecn. dei Prod. Erbor. Referente Incaricato per le procedure part-time
2014 oggi Sapienza Università di Roma – Facoltà di Farmacia e Medicina – Corsi di Laurea in: Medicina e Chirurgia; Scienze Farmaceutiche Applicate Presidente d’Aula Commissioni test di Ingresso
2013 oggi Sapienza Università di Roma – Facoltà di Farmacia e Medicina PhD Course of Biochemistry, Membro del Collegio dei Docenti
2013 oggi MIUR Membro dell' Albo Revisori Progetti
2015 oggi European Union COST Action BM1405 – Non globular proteins – MC Member
2016 oggi ANVUR Evaluator VQR 2011-2014
2016 oggi European Union Member of the Evaluator Panels of FET-OPEN - NOVEL IDEAS FOR RADICALLY NEW TECHNOLOGIES







Part IV – Attività didattica



2004-2010 Sapienza, Università di Roma Modulo “Struttura della Cellula e Meccanismi di duplicazione Cellulare”, Professioni Sanitarie in Tecniche Audioprotesiche;
2004-2010 Sapienza, Università di Roma Modulo “Struttura della Cellula e Meccanismi di duplicazione Cellulare”, Professioni Sanitarie in Tecniche Audiometristiche
2004-2012 Sapienza, Università di Roma Member of the commission for the exam of “Chimica e Propedeutica Biochimica” in the course of “Medicina e Chirurgia”
2013-2015 Sapienza, Università di Roma Corso di Laurea in Medicina e Chirurgia – CLMMC “E” - Corso di “Chimica e Prop. Biochimica”
2013-oggi Sapienza, Università di Romae Corso di Laurea in Scienze Farmaceutiche Applicate – Corso di “Biotecnologie Modecolari”
2015-oggi Sapienza, Università di Roma Corso di Laurea in Tecnico di Laboratorio Biomedico (Sede di Pozzilli –NEUROMED) – Corso di Basi Fisiche e Chimiche – Titolare del Corso in Chimica e Prop. Biochimica e Co-ordinatore di corso Integrato
2015-oggi Sapienza, Università di Roma Corso di Laurea in Tecniche di Radiologia Medica per Immagini e Radioterapia (Sede di Pozzilli –NEUROMED) – Corso di Basi Fisiche e Chimiche – Titolare del Corso in Chimica e Prop. Biochimica
2013 -oggi Sapienza, Università di Roma Relatore di tesi di Laurea per tesi di Laurea in Fisica, Chimica e Scienze Farmacuetiche Applicate.
2013 - oggi Sapienza, Università di Roma Docente Guida presso il Dottorato di Ricerca in Biochimica di PhD students.

2017-oggi Coordinatore del Dottorato di Ricerca in Scienze Biochimiche, Sapienza, Università di Roma













Part V - - Membro di Società, Editorial Board, Premi


2009 Accademia Nazionale delle Scienze, detta dei XL, e Accademia Nazionale dei Lincei. “Vincenzo Caglioti" International Prize for Chemistry
2010 Young Researcher Prize, CNR Department of Life Sciences (awarded by the Director and including a grant of 5.000 Euro for research)
2008-2014 Membro of the Italian Society of Biochemistry and Molecular Biology (SIB)
2005-oggi Membro dell'Editorial Board di Protein Engineering Design & Selection (Oxford Journals)
2008-2015 Membro dell'Editorial Board di Research Letters in Biochemistry (Hindawi)
2014-oggi Membro dell'Editorial Board di Scientific Reports (Nature Publishing Group)
2015-oggi Membro dell'Editorial Board di Biophysical Chemistry (Elsevier)
2017-oggi Membro dell'Editorial Board di Protein and Peptide Letter (Bentham Science)
2017-oggi Membro dell'Editorial Board di International Journal of Molecular Sciences (MDPI)
2020 Accademia Nazionale delle Scienze, detta dei X, Medaglia "Emilia Chiancone" per la Biologia Molecolare
2020 Accademia Nazionale dei Lincei, Premio Tartufari per la Biologia

Part VI - Funding Information [grants as PI-principal investigator or I-investigator]


2011 -2013 The dark side of protein folding: denatured states and misfolded species in molecular recognition and pathological processes. Istituto Pasteur Fondazione Cenci Bolognetti – Investigator 60k Euro
2013 No structure but function: the new paradigm of modern biophysics (C26A13T9NB) Sapienza Progetti di Ricerca di Università - Principal Investigator
12k Euro
2014 - 2016 PDZ Domains and Cancer Istituto Pasteur Fondazione Cenci Bolognetti – Progetti di Ricerca Under 40 – Principal Investigator 90k Euro
2015 - 2018 Meccanismi molecolari del folding di proteine intrinsecamente disordinate
Università Italo Francese – Bando Vinci – Principal Investigator 60k Euro
2015 - 2018 Unveiling the role protein disorder in molecular interaction and signaling (C26A155S48)
Sapienza Progetti di Ricerca di Università - Principal Investigator
31k Euro
2016 - 2019 PDZnet (EU proposal 675341) European Union – Marie Curie International Training Network – Beneficiary Investigator 250k Euro
2017 - 2020 AIRC My First AIRC Grant - Principal Investigator - 205k Euro
2020 - 2024 UBIMOTIF (EU proposal 860517) European Union – Marie Curie International Training Network – Beneficiary Investigator 250k Euro
2021 - 2025 AIRC Investigator Grant - Principal Investigator - 400k Euro
2023 - 2027 IDPro (EU proposal 10119633) European Union – Marie Curie International Training Network – Beneficiary Investigator 250k Euro

Part VII – Pubblicazioni e comunicazioni

Pubblicazioni internazionali 153

Hirsch (H) index 38


Invited Talks e seminari:

Il Prof. Gianni ha comunicato oltre 30 seminari in conferenze nazionali ed internazionali (Comprese una FEBS annual meeting e due Protein Society annual meetings)
Membro dell' Organizing Committee of the International Conference
Protein Structure and Dynamics, 1-3 Dec 2010, Acc. Naz. Dei Lincei, Rome Italy
Membro dello Scientific Committee of the International Conference
Proteine, 31 Mar-1 Apr 2014, Padua, Italy.

PUBBLICAZIONI

1) Gianni, S., Travaglini-Allocatelli, C., Cutruzzolà, F., Bigotti, M.G. & Brunori, M. (2001). Snapshots of protein folding. A study on the multiple transition state pathway of cytochrome c551 from Pseudomonas aeruginosa. J. Mol. Biol., 309, 1177-87.

2) Gianni, S., Brunori, M. & Travaglini-Allocatelli, C. (2001). Refolding kinetics of cytochrome c551 reveals mechanistic defference between urea and guanidine. Protein Science, 10, 1685-1688

3) Arcovito, A., Gianni, S., Brunori, M., Travaglini-Allocatelli, C. & Bellelli, A. (2001). Fast coordination changes in cytochrome c do not necessarily imply folding. J. Biol. Chem. 276, 41073-41078.

4) Brunori, M., Bigotti, M.G., Cutruzzolà, F., Gianni, S. & Travaglini-Allocatelli, C. (2003) Cytochrome c551 as a model system for protein folding. Biophys. Chem. 100, 409-419.

5) Gianni, S., Travaglini-Allocatelli, C., Cutruzzolà, F., Brunori, M., Ramachandra Shastry, M.C. & Roder, H. (2003) Parallel pathways in cytochrome c551 folding. J. Mol. Biol. 330, 1145-1152 .

6) Travaglini-Allocatelli, C., Gianni, S., Morea, V., Tramontano, A., Soulimane, T. & Brunori, M. (2003) Exploring the cytochrome c folding mechanisms: cyt c552 from Thermus thermophilus folds through an on-pathway intermediate. J. Biol. Chem., 278, 41136-41140 .

7) Gianni, S., Guydosh, N.R., Khan, F., Caldas, T.D., Mayor, U., White, G.W.N., DeMarco, M.L., Daggett, V. & Fersht A.R. (2003) Unifying features in protein folding mechanisms. Proc. Natl. Acad. Sci USA, 100, 13286-13291.

8) Khan, F., Chuang, J.I., Gianni, S. and Fersht, A.R. (2003)The kinetic pathway of folding of barnase. J. Mol. Biol., 333, 169-186.

9) Gianni, S., Mayor, U. and Fersht, A.R. (2003) Structural insights in the folding of single domain proteins. Ital. J. Biochem., 52, 157-161.

10) Jemth, P.*, Gianni S.*, Day, R., Li, B., Johnson, C.M., Daggett, V. and Fersht, A.R. (2004) Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation. Proc. Natl. Acad. Sci USA, 101, 6450-6455.

11) Travaglini-Allocatelli, C., Gianni, S. and Brunori, M. (2004) A common folding mechanism in the cytochrome c family. Trends Bioch. Sci., 29, 535-541.

12) White, G.W.N.*, Gianni, S.*, Grossman, J.G., Jemth, P., Fersht, A.R., and Daggett, V. (2005) Simulation and Experiment Conspire to reveal Cryptic Intermediates and the Slide from Framework to Nucleation-Condensation Mechanism in the Folding of the Homeodomain Superfamily. J. Mol. Biol., 350, 757-775.

13) Jemth, P., Day, R., Gianni, S., Khan, F., Allen, M. D., Daggett, V., and Fersht, A. R. (2005) The structure of the major transition state for folding of an FF domain from experiment and simulation. J. Mol. Biol., 350, 363-378

14) Travaglini-Allocatelli, C.*, Gianni, S.*, Dubey, V.K., Borgia, A., Di Matteo, A., Bonivento, D., Cutruzzolà, F., Bren, K.L. and Brunori, M. (2005) An obligatory intermediate in the folding of cytochrome c552 from Hydrogenobacter thermophilus. J. Biol. Chem., 280, 25729-25734

15) Gianni S., Calosci, N., Aelen, J., Vuister, G.W., Brunori, M. and Travaglini-Allocatelli C. (2005) Kinetic folding mechanism of PDZ2 from PTP-BL, Protein Eng. Des. Sel., 18, 389-395.

16) Gianni, S., Engström, A., Larsson, M., Calosci, N., Malatesta, F., Eklund, L., Ngang, C.C., Travaglini-Allocatelli, C., and Jemth P., (2005) The Kinetics Of Pdz Domain – Ligand Interactions And Implications For The Binding Mechanism, J. Biol. Chem., 280, 34805-34812.

17) Chi, C.N, Engstrom, Å, Gianni, S., Larsson, M. and Jemth, P. (2006) Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain. J.Biol. Chem., 281, 36811-36888.

18) Gianni, S., Walma, T., Arcovito, A., Calosci, N., Bellelli, A., Engstrom, Å, Travaglini-Allocatelli, C., Brunori, M., Jemth, P. and Vuister, G.W. (2006) Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering. Structure, 14, 1801-1809.

19) Gianni, S., Geeierhaas, C.D., Calosci, N., Jemth, P., Vuister, G.W., Travaglini-Allocatelli, C., Vendruscolo, M. and Brunori M. (2007) A PDZ domain recapitulates a unifying mechanism for protein folding. Proc. Natl. Acad. Sci USA, 104, 128-133.

20) Federici, L., Masulli, M., Bonivento, D., Di Matteo, A., Gianni, S., Favaloro, B., Di Ilio, C. and Allocati, N., (2007) Role of Ser11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase. Biochem J. 2007 403, 267-274

21) Ivarsson, Y., Travaglini-Allocatelli, C., Jemth, P., Malatesta, F., Brunori, M. and Gianni, S.† (2007) An on-pathway intermediate in the folding of a PDZ domain.
J Biol Chem. 282, 8568-8572

22) Chi, C.N*, Gianni, S.*†, Calosci, N., Travaglini-Allocatelli, C. Engstrom, Å, and Jemth, P. (2007) A conserved folding mechanism for PDZ domains. FEBS Letters 2007 581, 1109-1113.

23) Gianni, S.†, Ivarsson, Y., Jemth, P., Brunori, M., Travaglini-Allocatelli, C. (2007) Identification and characterization of protein folding intermediates. Biophys. Chem 128, 105-113.

24) Gianni, S., Brunori, M., Travaglini-Allocatelli, C., (2007) Plasticity of the protein folding landscape: switching between on and off-pathway intermediates Arch. Biochem. Biophys. 466 172-176.

25) Di Matteo, A., Gianni, S., Schininà, M.E., Giorgi, A., Altieri, F., Calosci, N., Brunori, M., Travaglini-Allocatelli, C. (2007) A strategic protein in cytochrome c maturation: 3D structure of CcmH and binding to apocytochrome c. J. Biol. Chem. 282, 27012-27019.

26) Jemth, P., Gianni, S.† (2007) PDZ domains: folding and binding. Biochemistry 46, 8701-8708

27) Gianni, S.†, Ivarsson, Y., Bah, A., Bush-Pelic, L.A., Di Cera, E. (2007) Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics. Biophys. Chem. 131, 111-114.

28) Ivarsson, Y., Travaglini-Allocatelli, C., Morea, V., Brunori, M., Gianni, S.† (2008) The folding pathway of an engineered circularly permuted PDZ domain. Protein Eng. Des. Sel 21 155-160.

29) Ivarsson, Y., Travaglini-Allocatelli, C., Brunori, M., Gianni, S.† (2008) Mechanisms of proten folding. Eur. Biophys. J. 37, 721-728

30) Jemth, P., Johnson, C.M., Gianni, S., Fersht, A.R. (2008) Demonstration by burst phase analysis of a robust folding intermediate in the FF domain Protein Eng. Des. Sel. 21, 207-214.

31) Ivarsson, Y, Travaglini-Allocatelli, C., Brunori, M., Gianni, S.†, (2008) Folding and Misfolding in a naturally circularly permuted PDZ domain. J. Biol. Chem. 283, 8954-8960.

32) Borgia, A., Gianni, S., Brunori, M., Travaglini-Allocatelli, C., (2008) Fast folding kinetics and stabilization of apo-cytochrome c FEBS Letters .582 1003-1007.

33) Parrini, C., Bemporad, F., Baroncelli, A., Gianni, S., Travaglini-Allocatelli, C., Kohn, J.E., Ramazzotti, M., Chiti, F., Taddei, N., (2008) The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond. J. Mol. Biol. 379, 1107-1118.

34) Calosci, N., Chi, C.N., Richter, B., Camilloni, C., Engstrom, A, Eklund, L, Travaglini-Allocatelli, C., Gianni, S.†, Vendruscolo, M.†, Jemth, P.†, (2008) Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins Proc. Natl. Acad. Sci. USA, 105, 19241-19246.

35) Sicorello, A., Torrassa, S., Soldi, G., Gianni, S., Travaglini-Allocatelli, C., Taddei, N., Relini, A., Chiti, F., (2009) Agitation and high ionic strength induce amyloidogenesis of a folded PDZ domain in native conditions Biophys. J 96, 2289-2298.

36) Travaglini-Allocatelli, C., Ivarsson, Y., Jemth, P., and Gianni, S.,† (2009) Folding and stability of globular proteins and implications for function. Curr. Opin. Struct. Biol. 19, 3-7.

37) Scaloni, F., Gianni, S., Federici, L., Falini, B., Brunori, M. (2009) Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance. FASEB J. 23, 2360-2365.

38) Federici, L., Masulli, M., Gianni, S., Di Ilio, C., Allocati, N. (2009) A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases. Biochem Biophys Res Commun. 382: 525-529.

39) Ivarsson, Y., Travaglini-Allocatelli, C., Brunori, M., Gianni, S., (2009) Engineered symmetric connectivity highlights malleability in protein folding pathways J. Am. Chem. Soc. 131, 11727-11733.

40) Chi, C.N., Bach, A., Engström, A., Wang, H., Strømgaard, K., Gianni, S.†, Jemth, P. † (2009) A sequential binding mechanism in a PDZ domain. Biochemistry. 48, 7089-7097.

41) Savino, C., Montemiglio, L.C., Sciara, G., Miele, A.E., Kendrew, S.G., Jemth, P., Gianni, S.†, Vallone, B., (2009) Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate. J. Biol. Chem. 284, 29170-29179.

42) Gianni, S., Brunori, M., Jemth, P., Oliveberg, M., Zhang, M., (2009) Distinguishing between smooth and rough free energy barriers in protein folding. Biochemistry 48, 11825-11830.

43) Giansanti, F., Di Leandro, L., Koutris, I., Pitari, G., Fabbrini, M.S., Lombardi, A., Flavell, D.J., Flavell, S.U., Gianni, S. †, Ippoliti, R. (2010) Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants. Protein Eng. Des, Sel. 23. 61-68.

44) Scaloni, F., Federici, L., Brunori, M., Gianni, S., (2010) Deciphering the folding transition state structure and denatured state properties of nucleophosmin C-terminal domain. Proc. Natl. Acad. Sci, USA 107, 5447-5452.

45) Haq, S.R., Jurgens, M.C., Chi, C.N., Koh, C.S., Elfstrom, L., Selmer, M., Gianni, S†, Jemth, P (2010) The plastic energy landscape of protein folding: a triangular folding mechanism with an equilibrium intermediate for a small protein domain. J Biol Chem. 285, 18051-18059

46) Di Matteo, A., Calosci, N., Gianni ,S., Jemth, P., Brunori, M., Travaglini-Allocatelli, C. (2010) Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins. Struct. Funct. Bioinf. 78, 2213-21.

47) Montemiglio, L.C., Gianni, S., Vallone, B., Savino, C. (2010) Azole drugs trap cytochrome P450 EryK in alternative conformational states. Biochemistry 49, 9199-9206.

48) Gianni, S., Ivarsson, Y., De Simone, A., Travaglini-Allocatelli, C., Brunori, M., Vendruscolo M., (2010) Characterization of the Structure of a Misfolded Intermediate Populated during the Folding Process of a PDZ domain Nature Struct. Mol Biol. 17, 1431-1437.

49) Morrone, A., McCully, M.E., Bryan, P.N., Brunori, M., Daggett, V., Gianni, S.†, Travaglini-Allocatelli, C., (2011) The denatured state dictates the topology of two proteins with almost identical sequence but different native structure and function. J. Biol., Chem. . 286, 3863-3872.

50) Gianni, S., Haq, S.R., Montemiglio, L.C., Jürgens, M.C., Engström, Å., Chi, C.N., Brunori, M., Jemth, P. (2011) Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity. J. Biol. Chem. 286, 27167-27175.

51) Morrone, A., Giri, R., Toofanny, R.D., Travaglini-Allocatelli, C., Brunori, M., Daggett, V., Gianni, S.†, (2011) GB1 is not a two-state folder: identification and characterization of an on-pathway intermadiate. Biophys. J 101, 2053-2060.

52) Giardina, G., Montioli, R., Gianni, S., Cellini, B., Paiardini, A., Borri-Voltattorni, C., Cutruzzolà, F., (2011) The open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. Proc. Natl. Acad. Sci. USA 108, 20514-20519.

53) Haq SR, Chi CN, Bach A, Dogan J, Engström A, Hultqvist G, Karlsson A, Lundström P, Montemiglio LC, Strømgaard K, Gianni S, Jemth P. (2011) Side chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. J. Am. Chem. Soc. 134, 599-605


54) Brunori, M., Gianni, S., Giri, R., Morrone, A., Travaglini-Allocatelli, C., (2012) Morphogenesis of a protein: folding pathways and the energy landscape Bioch. Soc. Trans 40(2):429-32.

55) Hultqvist G, Pedersen SW, Chi CN, Strømgaard K, Gianni S, Jemth P. (2012) An expanded view of the protein folding landscape of PDZ domains. Biochem Biophys Res Commun. 421, 550-553.

56) Chi, C.N., Bach, A., Stromgaard, K., Gianni, S., Jemth, P., (2012) Ligand binding by PDZ domains. Biofactors, 38, 338-348.

57) Giri., R., Morrone, A., Travaglini-Allocatelli C., Jemth, P., Brunori, M., Gianni, S.†, (2012) The folding pathways of proteins with increasing degree of sequence identities but different structure and function. Proc. Natl. Acad. Sci. USA. 109, 17772-17776.

58) Morrone, A., Giri, R., Brunori, M., Gianni S. †, (2012) Reassessing the folding of the KIX domain: Evidence for a two-state mechanism Protein Sci. 21, 1775-1779.

59) Gianni, S. †, Morrone, A., Giri, R., Brunori, M. (2012) A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein. Biochem Biophys Res Commun. 428, 205-209

60) Chi CN, Haq SR, Rinaldo S, Dogan J, Cutruzzolà F, Engström A, Gianni S, Lundström P, Jemth P. (2012) Interactions outside the Boundaries of the Canonical Binding Groove of a PDZ Domain Influence Ligand Binding. Biochemistry. 51, 8971-8979

61) Polticelli, F., Caprari, S., Gianni, S., Ascenzi, P., (2012) GA/GB Fold switching may modulate fatty acid transfer from human serum albumin to bacteria. IUBMB Life 64, 885-888.

62) Hultqvist, G., Punekar, A., Morrone, A., Chi, C.N., Engstrom, A, Selmer, M, Gianni, S. †, Jemth, P., (2012) Tolerance of protein folding to a circular permutation in a PDZ domain, PLOS ONE, 7, e50055

63) Chiarella, S., Federici, L., Di Matteo, A., Brunori, M., Gianni, S. †, (2013) The folding pathway of a functionally competent C-terminal domain of nucleophosmin: protein stability and denatured state residual structure. Biochem Biophys Res Commun. 435, 64-68.

64) Ascenzi, P., and Gianni S. †, (2013) On the functional role of reaction intermediates: rediscovering "chronosteric effects" thirty years later. IUBMB Life, 65, 836-844

65) Eildal JN, Hultqvist G, Balle T, Stuhr-Hansen N, Padrah S, Gianni S, Strømgaard K, Jemth P. (2013) Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations J. Am. Chem. Soc. 135, 12998-13007

66) Hultqvist G, Haq SR, Punekar AS, Chi CN, Engström Å, Bach A, Strømgaard K, Selmer M, Gianni, S. †, Jemth P. (2013) Energetic pathway sampling in a protein interaction domain. Structure. 21, 1193-1202.

67) Giri R, Morrone A, Toto A, Brunori M, Gianni, S. † (2013) Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system. Proc Natl Acad Sci U S A. 110, 149422-149427

68) Dogan, J., Gianni, S. †, Jemth, P. (2014) The binding mechanisms of intrinsically disordered proteins Phys. Chem. Chem. Phys. 16, 6323-6331

69) Bonetti D, Toto A, Giri R, Morrone A, Sanfelice D, Pastore A, Temussi P, Gianni, S. †, Brunori M. (2014) The kinetics of folding of frataxin. Phys Chem Chem Phys. 16, 6391-6397.

70) Gianni, S. †, Dogan J, Jemth P. (2014) Distinguishing induced fit from conformational selection. Biophys. Chem. 189, 33-39.

71) Toto A, Giri R, Brunori M, Gianni, S. † (2014) The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb. Protein Sci. 23, 962-969.

72) Di Silvio, E., Bonetti, D., Toto, A., Morrone, A., Gianni, S. † (2014) The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor. Protein Eng. Des. Sel. 27, 249-253

73) Gianni, S. † Jemth, P., (2014) Conserved nucleation sites reinforce the significance of Phi value analysis in protein-folding studies. IUBMB Life 66, 449-452

74) Conti, S., Li, X., Gianni, S., Ghadami, S. A., Buxbaum, J., Cecchi, C., Chiti, F., Bemporad, F., (2014) A complex equilibrium among partially unfolded conformations in monomeric transthyretin. Biochemistry 53, 4381-4392

75) Gianni, S. †, Camilloni, C., Giri, R., Toto, A., Bonetti, D., Morrone, A., Sormanni, P, Brunori, M., Vendruscolo, M. (2014) Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein. Proc. Natl. Acad. Sci. USA 111, 14141-14146

76) Dosnon, M., Bonetti, D., Morrone, A., Erales, J., Di Silvio, E., Longhi, S., Gianni, S. † (2015) Demonstration of a Folding after Binding Mechanism in the Recognition between the Measles Virus NTAIL and X Domains. ACS Chem Biol 10, 795-802.

77) Di Silvio, E., Toto, A., Bonetti, D., Morrone, A., Gianni, S. † (2015) Understanding the effect of alternative splicing in the folding and function of the second PDZ from protein tyrosine phosphatase-BL. Sci Rep. 5: 9299.

78) Di Silvio, E., Brunori, M., Gianni, S. † (2015) Frustration Scuplts the early stages of protein folding Angew Chem Int Ed Engl 54, 10867-10869.

79) Gruet A, Dosnon M, Blocquel D, Brunel J, Gerlier D, Das RK, Bonetti D, Gianni, S., Fuxreiter M, Longhi S, Bignon C. (2016) Fuzzy regions in an intrinsically disordered protein impair protein-protein interactions. FEBS J.

80) Gianni, S., Dogan, J., Jemth, P. (2016) Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics? Curr. Opin. Struct. Biol. 38, 18-24.

81) Toto A, Camilloni C, Giri R, Brunori M, Vendruscolo M, Gianni, S. † (2016) Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein Sci. Rep. 6 21994

82) Toto A, Pedersen SW, Karlsson OA, Moran GE, Andersson E, Chi CN, Strømgaard K, Gianni, S. † Jemth P. (2016) Ligand binding to the PDZ domains of postsynaptic density protein 95. Protein Eng. Des. Sel. Mar 2 [epub ahead of print]

83) Gianni, S. †, Jemth, P. (2016) Protein Folding: Vexing debates on a fundamental problem. Biophys. Chem 212, 17-21

84) Bonetti D, Camilloni C, Visconti L, Longhi S, Brunori M, Vendruscolo M, Gianni, S. † (2016) Identification and Structural Characterization of an Intermediate in the Folding of the Measles Virus X domain. J. Biol. Chem. Mar 21 [epub ahead of print]

85) Camilloni, C., Bonetti, D., Morrone, D., Giri, R., Dobson, C. M., Brunori, M., Gianni, S. † , Vendruscolo, M. (2016) Structural Biology of the hydrophobic effect in protein folding Sci. Rep. Accepted for publication.

86) Toto, A., Gianni, S. † (2016) Mutational Analysis of the Binding-Induced Folding Reaction of the Mixed-Lineage Leukemia Protein to the KIX Domain. Biochemistry. 55, 3957-3962

87) Dogan J, Toto A, Andersson E, Gianni, S. †, Jemth P. (2016) Activation Barrier-Limited Folding and Conformational Sampling of a Dynamic Protein Domain. Biochemistry. 55, 5289-5295.

88) Toto A, Mattei A, Jemth P, Gianni, S. †, (2016) Understanding the role of phosphorylation in the binding mechanism of a PDZ domain. Protein Eng Des Sel. 2016 Oct 19. [Epub ahead of print]

89) Brunori M, Gianni, S. † .(2016) Molecuar Medicine – To be or not to be Biophys Chem. 2016 Jul-Aug;214-215:33-46.

90) Kukic P, Pustovalova Y, Camilloni C, Gianni, S., Korzhnev DM, Vendruscolo M. (2017) Structural Characterization of the Early Events in the Nucleation- Condensation Mechanism in a Protein Folding Process. J Am Chem Soc. 139, 6899- 6910.

91) Troilo F, Bonetti D, Toto A, Visconti L, Brunori M, Longhi S, Gianni, S. † (2017) The folding pathway of the KIX domain ACS Chem. Biol. 12, 1683-1690

92) Longhi S, Bloyet LM, Gianni, S., Gerlier D. (2017) How order and disorder within paramyxoviral nucleoproteins and phosphoproteins orchestrate the molecular interplay of transcription and replication. Cell Mol Life Sci. 74, 3091-3118.

93) Bonetti D, Troilo F, Toto A, Brunori M, Longhi S, Gianni, S. † (2017) Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering. Biochemistry 56, 3780-3786.

94) Caillet-Saguy C, Toto A, Guerois R, Maisonneuve P, di Silvio E, Sawyer K, Gianni, S. † Wolff N. (2017) Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains. Sci Rep. 7, 7875.

95) Toto, A., Bonetti, D., De Simone A., Gianni, S. † (2017) Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2 Oncotarget 8, 82344-82351.

96) Gautier C, Visconti L, Jemth P, Gianni S. † (2017) Addressing the role of the α-helical extension in the folding of the third PDZ domain from PSD-95. Sci Rep. 7, 12593.

97) Gianni S†, Jemth P. (2017) How Fast Is Protein-Ligand Association? Trends Biochem Sci. 42, 847-849.

98) Bignon C, Troilo F, Gianni S, Longhi S. (2017) Partner-Mediated Polymorphism of an Intrinsically Disordered Protein. J Mol Biol. S0022-2836(17)30562-4.

99) Schramm A, Lieutaud P, Gianni S, Longhi S, Bignon C. (2017) InSiDDe: A Server for Designing Artificial Disordered Proteins. Int J Mol Sci. 19: E91.

100) Saponaro, C., Sergio, S., Coluccia, A., De Luca, M., La Regina, G., Mologni, L., Famiglini, V.,Naccarato, V., Bonetti, D., Gautier, C., Gianni, S., Vergara, D., Salzet, M., Fournier, I., Bucci, C., Silvestri, R., Gambacorti Passerini, C., Maffia, M., Coluccia, A.M.L (2018) β-Catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy Oncogene. 2018 Mar 19.

101) Caflisch, A., Gianni, S.†, (2018) Curr Opin Struct. Biol. 48:iv-vii.

102) Bonetti D, Troilo F, Brunori M, Longhi S, Gianni S. (2018) How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein? Biophys J.114, 1889-1894.

103) Del Poggetto E, Toto A, Aloise C, Di Piro F, Gori L, Malatesta F, Gianni S, Chiti F, Bemporad F. (2018) Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity. J Biol Chem. 2018 May 14. pii: jbc.RA118.002087.

104) Malgieri G, D'Abrosca G, Pirone L, Toto A, Palmieri M, Russo L, Sciacca MFM, Tatè R, Sivo V, Baglivo I, Majewska R, Coletta M, Pedone PV, Isernia C, De Stefano M, Gianni S, Pedone EM, Milardi D, Fattorusso R. (2018) Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins. Chem Sci. 9: 3290-3298.

105) Bignon C, Troilo F, Gianni S, Longhi S. Modulation of Measles Virus NTAIL Interactions through Fuzziness and Sequence Features of Disordered Binding Sites. (2018) Biomolecules. 2018; 9, E8.

106) Karlsson E, Andersson E, Dogan J, Gianni S, Jemth P, Camilloni C. A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins. (2019) J Biol Chem. 294, 1230-1239

107) Troilo F, Bignon C, Gianni S, Fuxreiter M, Longhi S. (2018) Experimental Characterization of Fuzzy Protein Assemblies: Interactions of Paramyxoviral NTAIL Domains With Their Functional Partners. Methods Enzymol. 611:137-192.

108) Gianni S, McCully ME, Malagrinò F, Bonetti D, De Simone A, Brunori M, Daggett V. (2018) A Carboxylate to Amide Substitution That Switches Protein Folds. Angew Chem Int Ed Engl. 2018 57:12795-12798.

109) Troilo F, Bonetti D, Camilloni C, Toto A, Longhi S, Brunori M, Gianni S†. (2018) Folding Mechanism of the SH3 Domain from Grb2. J Phys Chem B. 122(49):11166-11173.

110) Bonetti D, Troilo F, Toto A, Travaglini-Allocatelli C, Brunori M, Gianni S†. (2018) Mechanism of Folding and Binding of the N-Terminal SH2 Domain from SHP2. J Phys Chem B. 122(49):11108-11114.

111) Visconti L, Malagrinò F, Toto A, Gianni S.† (2019) The kinetics of folding of the NSH2 domain from p85. Sci Rep. 9, 4058

112) Troilo F, Bonetti D, Bignon C, Longhi S, Gianni S.†(2019) Understanding Intramolecular Crosstalk in an Intrinsically Disordered Protein. ACS Chem Biol. 14, 337-341.

113) Visconti L, Malagrinò F, Broggini L, De Luca CMG, Moda F, Gianni S†, Ricagno S, Toto A. (2019) Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State. Int J Mol Sci. 20 pii: E396.

114) Coluccia A, La Regina G, Naccarato V, Nalli M, Orlando V, Biagioni S, De Angelis ML, Baiocchi M, Gautier C, Gianni S, Di Pastena F, Di Magno L, Canettieri G, Coluccia AML, Silvestri R. (2019) Drug Design and Synthesis of First in Class PDZ1 Targeting NHERF1 Inhibitors as Anticancer Agents. ACS Med Chem Lett, 10, 499-503

115) Malagrinò F, Troilo F, Bonetti D, Toto A, Gianni, S. † (2019) Mapping the allosteric network within a SH3 domain. Sci Rep. 2019 9:8279.

116) Visconti L, Malagrinò F, Gianni, S. †, Toto A. (2019) Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2. FEBS J. 286(23):4769-4777.

117) Gianni, S. †, Jemth P. (2019) Affinity versus specificity in coupled binding and folding reactions. Protein Eng Des Sel. 32:203.

118) Toto A, Troilo F, Visconti L, Malagrinò F, Bignon C, Longhi S, Gianni, S. †, (2019) Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD. Arch Biochem Biophys. 671:255-261.

119) Petrosino M, Pasquo A, Novak L, Toto A, Gianni S, Mantuano E, Veneziano L, Minicozzi V, Pastore A, Puglisi R, Capriotti E, Chiaraluce R, Consalvi V. (2019) Characterization of human frataxin missense variants in cancer tissues. Hum Mutat. 2019 Sep;40(9):1400-1413.

120) Troilo F, Malagrinò F, Visconti L, Toto A, Gianni S. (2019) The Effect of Proline cis-trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85. Int J Mol Sci. 2019 Dec 23;21(1). pii: E125.

121) Laursen, L, Karlsson, E., Gianni, S. †, Jemth, P., (2020) Functional interplay between protein domains in a supramodular structure J. Biol. Chem, J Biol Chem. 2020 Feb 14;295(7):1992-2000.

122) Toto A, Malagrinò F, Visconti L, Troilo F, Gianni S. (2020) Unveiling the Molecular Basis of the Noonan Syndrome-Causing Mutation T42A of SHP2. Int J Mol Sci. 2020 Jan 10;21(2). pii: E461.

123) Gautier, C., Gianni, S. †, (2020) Unveiling the folding mechanism of PDZ domains Methods Mol. Biol. Accepted for publication

124) Toto, A., Troilo, F., Malagrinò, F., Gianni, S. †, (2020) Understanding binding induced folding by temperature jump Methods Mol. Biol.2141:651-661.

125) Toto A, Malagrinò F, Visconti L, Troilo F, Pagano L, Brunori M, Jemth P, Gianni S. (2020) Templated folding of intrinsically disordered proteins J Biol Chem. 2020 May 8;295(19):6586-6593.

126) Malagrinò F, Visconti L, Pagano L, Toto A, Troilo F, Gianni S. (2020) Understanding the Binding Induced Folding of Intrinsically Disordered Proteins by Protein Engineering: Caveats and Pitfalls Int J Mol Sci. 2020 May 15;21(10):3484.

127) Visconti L, Toto A, Jarvis JA, Troilo F, Malagrinò F, De Simone A, Gianni S. (2020) Demonstration of Binding Induced Structural Plasticity in a SH2 Domain Front Mol Biosci. 2020 May 12;7:89.

128) Gautier C, Troilo F, Cordier F, Malagrinò F, Toto A, Visconti L, Zhu Y, Brunori M, Wolff N, Gianni S. (2020) Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19963-19969.

129) Toto A, Ma S, Malagrinò F, Visconti L, Pagano L, Stromgaard K, Gianni S. (2020) Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein Protein Sci. 2020 Oct;29(10):2038-2042.

130) Laursen L, Kliche J, Gianni S, Jemth P. (2020) Supertertiary protein structure affects an allosteric network. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24294-24304.

131) Gianni S, Jemth P. (2020) Direct Quantification of Protein Dimerization Preference Shed Light on SOD1-associated ALS J Mol Biol. 2020 Nov 20;432(23):6003-6004.

132) Malagrinò F, Coluccia A, Bufano M, Regina G, Puxeddu M, Toto A, Visconti L, Paone A, Magnifico MC, Troilo F, Cutruzzolà F, Silvestri R, Gianni S. (2020) Targeting the Interaction between the SH3 Domain of Grb2 and Gab2. Cells. 2020 Nov 7;9(11):2435.

133) Pagano L, Toto A, Malagrinò F, Visconti L, Jemth P, Gianni S. (2021) Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery. Int J Mol Sci. 2021 Jan 15;22(2):828.

134) Visconti L, Malagrinò F, Troilo F, Pagano L, Toto A, Gianni S. (2021) Folding and Misfolding of a PDZ Tandem Repeat. J Mol Biol. 2021 Apr 2;433(7):166862

135) Gianni S, Freiberger MI, Jemth P, Ferreiro DU, Wolynes PG, Fuxreiter M. (2021) Fuzziness and Frustration in the Energy Landscape of Protein Folding, Function, and Assembly Acc Chem Res. 2021 Mar 2;54(5):1251-1259.

136) Fusco G, Gianni S. (2021) Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins Life (Basel) 2021 Feb 12;11(2):140.

137) Nalli M, Puxeddu M, La Regina G, Gianni S, Silvestri R. Emerging Therapeutic Agents for Colorectal Cancer. Molecules. 2021 Dec 9;26(24):7463. doi: 10.3390/molecules26247463.

138) Pagano L, Malagrinò F, Nardella C, Gianni S, Toto A. Experimental Characterization of the Interaction between the N-Terminal SH3 Domain of Crkl and C3G. Int J Mol Sci. 2021 Dec 7;22(24):13174.

139) Nardella C, Malagrinò F, Pagano L, Rinaldo S, Gianni S, Toto A. Determining folding and binding properties of the C-terminal SH2 domain of SHP2. Protein Sci. 2021 Dec;30(12):2385-2395. doi: 10.1002/pro.4201.

140) Nardella C, Visconti L, Malagrinò F, Pagano L, Bufano M, Nalli M, Coluccia A, La Regina G, Silvestri R, Gianni S, Toto A. Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer. Biol Direct. 2021 Oct 12;16(1):15. doi: 10.1186/s13062-021-00303-9.

141) Laursen L, Gianni S, Jemth P. Dissecting Inter-domain Cooperativity in the Folding of a Multi Domain Protein. J Mol Biol. 2021 Sep 3;433(18):167148. doi: 10.1016/j.jmb.2021.167148. Epub 2021 Jul 8.

142) Pagano L, Malagrinò F, Visconti L, Troilo F, Pennacchietti V, Nardella C, Toto A, Gianni S. Probing the Effects of Local Frustration in the Folding of a Multidomain Protein. J Mol Biol. 2021 Jul 23;433(15):167087. doi: 10.1016/j.jmb.2021.167087. Epub 2021 Jun 3.

143) Malagrinò F, Pennacchietti V, Santorelli D, Pagano L, Nardella C, Diop A, Toto A, Gianni S. On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains Biomolecules. 2022 Jan 26;12(2):209. doi: 10.3390/biom12020209

144) Malagrinò F, Diop A, Pagano L, Nardella C, Toto A, Gianni S. Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes Curr Opin Struct Biol . 2022 Feb;72:153-160. doi: 10.1016/j.sbi.2021.11.004.

145) Coluccia A, Bufano M, La Regina G, Puxeddu M, Toto A, Paone A, Bouzidi A, Musto G, Badolati N, Orlando V, Biagioni S, Masci D, Cantatore C, Cirilli R, Cutruzzolà F, Gianni S, Stornaiuolo M, Silvestri R. Anticancer Activity of ( S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)- N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1 H-indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor Cancers (Basel). 2022 Mar 7;14(5):1358. doi: 10.3390/cancers14051358.

146) Toto A, Malagrinò F, Nardella C, Pennacchietti V, Pagano L, Santorelli D, Diop A, Gianni S. Characterization of early and late transition states of the folding pathway of a SH2 domain Protein Sci. 2022 Jun;31(6):e4332. doi: 10.1002/pro.4332.

147) Brunori M, Gianni S. An Outlook on the Complexity of Protein Morphogenesis in Health and Disease. Front Mol Biosci. 2022 Jun 13;9:909567. doi: 10.3389/fmolb.2022.909567.

148) Nardella C, Toto A, Santorelli D, Pagano L, Diop A, Pennacchietti V, Pietrangeli P, Marcocci L, Malagrinò F, Gianni S. Folding and Binding Mechanisms of the SH2 Domain from Crkl. Biomolecules. 2022 Jul 22;12(8):1014. doi: 10.3390/biom12081014.

149) Malagrinò F, Fusco G, Pennacchietti V, Toto A, Nardella C, Pagano L, de Simone A, Gianni S. Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat. Protein Sci. 2022 Sep;31(9):e4396. doi: 10.1002/pro.4396.

150) Gautier C, Gianni S. A short structural extension dictates the early stages of folding of a PDZ domain. Biochim Biophys Acta Proteins Proteom. 2022 Nov 1;1870(11-12):140852.

151) Pagano L, Pennacchietti V, Diop A, Santorelli D, Pietrangeli P, Marcocci L, Nardella C, Malagrinò F, Toto A, Gianni S. Exploring the effect of tethered domains on the folding of Grb2 protein.
Arch Biochem Biophys. 2022 Nov 30;731:109444.

152) Hollås H, Ramirez J, Nominé Y, Kostmann C, Toto A, Gianni S, Travé G, Vedeler A. The cooperative folding of annexin A2 relies on a transient nonnative intermediate. Biophys J. 2022 Dec 6;121(23):4492-4504.

153) Diop A, Santorelli D, Malagrinò F, Nardella C, Pennacchietti V, Pagano L, Marcocci L, Pietrangeli P, Gianni S, Toto A. SH2 Domains: Folding, Binding and Therapeutical Approaches. Int J Mol Sci. 2022 Dec 15;23(24):15944.

† Corresponding Author
* Shared First-Author


Produzione scientifica

11573/1706810 - 2024 - The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain
Di Felice, Mariana; Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Pietrangeli, Paola; Marcocci, Lucia; Di Matteo, Sara; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. - - issn: 0021-9258 - wos: (0) - scopus: 2-s2.0-85188713900 (0)

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11573/1680491 - 2023 - Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators
Bufano, Marianna; Puxeddu, Michela; Nalli, Marianna; La Regina, Giuseppe; Toto, Angelo; Liberati, Francesca Romana; Paone, Alessio; Cutruzzolà, Francesca; Masci, Domiziana; Bigogno, Chiara; Dondio, Giulio; Silvestri, Romano; Gianni, Stefano; Coluccia, Antonio - 01a Articolo in rivista
rivista: BIOORGANIC CHEMISTRY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 106607- - issn: 0045-2068 - wos: WOS:001007153500001 (0) - scopus: 2-s2.0-85159597372 (0)

11573/1683686 - 2023 - Biophysical characterization of the binding mechanism between the MATH domain of SPOP and its physiological partners
Diop, Awa; Pietrangeli, Paola; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 10138- - issn: 1422-0067 - wos: WOS:001017317000001 (2) - scopus: 2-s2.0-85163977385 (2)

11573/1695759 - 2023 - Addressing the binding mechanism of the Meprin and TRAF-C hmology domain of the Speckle-Type POZ protein using protein engineering
Diop, Awa; Pietrangeli, Paola; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001131010700001 (0) - scopus: (0)

11573/1670583 - 2023 - Allostery frustrates the experimentalist
Gianni, Stefano; Jemth, Per - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (Elsevier Health Sciences:11830 Westline Industrial Drive:Saint Louis, MO 63146:(800)545-2522, EMAIL: customerservice@elsevier.com, Fax: (314)453-4535) pp. 167934- - issn: 1089-8638 - wos: WOS:000918100900001 (6) - scopus: 2-s2.0-85146015417 (7)

11573/1685968 - 2023 - An intramolecular energetic network regulates ligand recognition in a SH2 domain
Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; Malagrinò, Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:001040354200001 (1) - scopus: 2-s2.0-85166371265 (3)

11573/1686025 - 2023 - Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands
Pennacchietti, Valeria; Pagano, Livia; Malagrinò, Francesca; Diop, Awa; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Pietrangeli, Paola; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 109703- - issn: 0003-9861 - wos: WOS:001053305400001 (0) - scopus: 2-s2.0-85166633882 (0)

11573/1673852 - 2023 - Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains
Santorelli, Daniele; Marcocci, Lucia; Pennacchietti, Valeria; Nardella, Caterina; Diop, Awa; Pietrangeli, Paola; Pagano, Livia; Toto, Angelo; Malagrino, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 102983- - issn: 0021-9258 - wos: WOS:001009100600001 (3) - scopus: 2-s2.0-85149793931 (3)

11573/1708917 - 2022 - An Outlook on the Complexity of Protein Morphogenesis in Health and Disease
Brunor, Maurizio; Gianni, Stefano - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. 1-9 - issn: 2296-889X - wos: WOS:000816852000001 (0) - scopus: 2-s2.0-85133548735 (0)

11573/1616528 - 2022 - Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor
Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano - 01a Articolo in rivista
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000773498900001 (4) - scopus: 2-s2.0-85131007159 (4)

11573/1662469 - 2022 - SH2 Domains: folding, binding and therapeutical approaches
Diop, Awa; Santorelli, Daniele; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 15944- - issn: 1422-0067 - wos: WOS:000902565100001 (9) - scopus: 2-s2.0-85144969444 (11)

11573/1708916 - 2022 - A short structural extension dictates the early stages of folding of a PDZ domain
Gautier, Candice; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (Tokyo ; Oxford ; New York ; London ; Amsterdam ; Shannon ; Paris : Elsevier) pp. 1-6 - issn: 1570-9639 - wos: WOS:000859328300002 (1) - scopus: 2-s2.0-85137114091 (1)

11573/1659078 - 2022 - The cooperative folding of annexin A2 relies on a transient nonnative intermediate
Hollås, Hanne; Ramirez, Juan; Nominé, Yves; Kostmann, Camille; Toto, Angelo; Gianni, Stefano; Travé, Gilles; Vedeler, Anni - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. - - issn: 0006-3495 - wos: WOS:000908349700009 (1) - scopus: 2-s2.0-85141976426 (1)

11573/1607647 - 2022 - On the effects of disordered tails, supertertiary structure and quinary interactions on the folding and function of protein domains
Malagrino, F.; Pennacchietti, V.; Santorelli, D.; Pagano, L.; Nardella, C.; Diop, A.; Toto, A.; Gianni, S. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 209- - issn: 2218-273X - wos: WOS:000763931100001 (6) - scopus: 2-s2.0-85123285981 (7)

11573/1652072 - 2022 - Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat
Malagrinò, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; De Simone, Alfonso; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000840110600001 (2) - scopus: 2-s2.0-85137125864 (4)

11573/1651291 - 2022 - Folding and binding mechanisms of the SH2 domain from Crkl
Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrinò, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. 1014- - issn: 2218-273X - wos: WOS:000846180000001 (4) - scopus: 2-s2.0-85137360513 (4)

11573/1657644 - 2022 - Exploring the effect of tethered domains on the folding of Grb2 protein
Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 109444- - issn: 0003-9861 - wos: WOS:000880049100004 (2) - scopus: 2-s2.0-85141826263 (3)

11573/1635685 - 2022 - Characterization of early and late transition states of the folding pathway of a SH2 domain
Toto, Angelo; Malagrinò, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000798704500001 (3) - scopus: 2-s2.0-85131218830 (3)

11573/1501450 - 2021 - Fuzziness and frustration in the energy landscape of protein folding, function, and assembly
Gianni, Stefano; Inés Freiberger, María; Jemth, Per; Ferreiro, Diego U.; Wolynes, Peter G.; Monika Fuxreiter, And - 01a Articolo in rivista
rivista: ACCOUNTS OF CHEMICAL RESEARCH (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. - - issn: 0001-4842 - wos: WOS:000626269900016 (73) - scopus: 2-s2.0-85101397929 (78)

11573/1593241 - 2021 - Unveiling induced folding of intrinsically disordered proteins - Protein engineering, frustration and emerging themes
Malagrinò, Francesca; Diop, Awa; Pagano, Livia; Nardella, Caterina; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 160-160 - issn: 0959-440X - wos: WOS:000768730600018 (13) - scopus: 2-s2.0-85120903843 (12)

11573/1604509 - 2021 - Emerging therapeutic agents for colorectal cancer
Nalli, M.; Puxeddu, M.; La Regina, G.; Gianni, S.; Silvestri, R. - 01a Articolo in rivista
rivista: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 7463-7463 - issn: 1420-3049 - wos: WOS:000736380500001 (14) - scopus: 2-s2.0-85121522712 (14)

11573/1577022 - 2021 - Determining folding and binding properties of the C-terminal SH2 domain of SHP2
Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000705532500001 (5) - scopus: 2-s2.0-85116539527 (6)

11573/1579282 - 2021 - Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer
Nardella, Caterina; Visconti, Lorenzo; Malagrinò, Francesca; Pagano, Livia; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: BIOLOGY DIRECT (London: BioMed Central) pp. - - issn: 1745-6150 - wos: WOS:000706722300001 (8) - scopus: 2-s2.0-85117321017 (13)

11573/1596175 - 2021 - Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g
Pagano, L.; Malagrino, F.; Nardella, C.; Gianni, S.; Toto, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 13174- - issn: 1661-6596 - wos: WOS:000738238000001 (1) - scopus: 2-s2.0-85120657305 (1)

11573/1552783 - 2021 - Probing the effects of local frustration in the folding of a multidomain protein
Pagano, Livia; Malagrinò, Francesca; Visconti, Lorenzo; Troilo, Francesca; Pennacchietti, Valeria; Nardella, Caterina; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 167087- - issn: 0022-2836 - wos: WOS:000672680300017 (6) - scopus: 2-s2.0-85107967375 (6)

11573/1477086 - 2021 - Double mutant cycles as a tool to address folding, binding, and allostery
Pagano, Livia; Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Jemth, Per; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 828- - issn: 1422-0067 - wos: WOS:000611298300001 (9) - scopus: 2-s2.0-85099547793 (12)

11573/1495668 - 2021 - Folding and misfolding of a PDZ tandem repeat
Visconti, Lorenzo; Malagrinò, Francesca; Troilo, Francesca; Pagano, Livia; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 166862- - issn: 0022-2836 - wos: WOS:000630007900009 (7) - scopus: 2-s2.0-85100673226 (9)

11573/1435307 - 2020 - Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate
Gautier, Candice; Troilo, Francesca; Cordier, Florence; Malagrinò, Francesca; Toto, Angelo; Visconti, Lorenzo; Zhu, Yanlei; Brunori, Maurizio; Wolff, Nicolas; Gianni, Stefano - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19963-19969-19969 - issn: 0027-8424 - wos: WOS:000567818600007 (12) - scopus: 2-s2.0-85089787733 (14)

11573/1464543 - 2020 - Supertertiary protein structure affects an allosteric network
Laursen, L; Kliche, J; Gianni, S; Jemth, P. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 24294-24304 - issn: 1091-6490 - wos: WOS:000576672700011 (20) - scopus: 2-s2.0-85092281157 (22)

11573/1456152 - 2020 - Targeting the interaction between the SH3 domain of Grb2 and Gab2
Malagrinò, Francesca; Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe; Puxeddu, Michela; Toto, Angelo; Visconti, Lorenzo; Paone, Alessio; Magnifico, Maria Chiara; Troilo, Francesca; Cutruzzolà, Francesca; Silvestri, Romano; Gianni, Stefano - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 2435- - issn: 2073-4409 - wos: WOS:000592940700001 (6) - scopus: 2-s2.0-85096028884 (6)

11573/1401198 - 2020 - Understanding the binding induced folding of intrinsically disordered proteins by protein engineering: caveats and pitfalls
Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Toto, Angelo; Troilo, Francesca; Gianni, Stefano - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 3484- - issn: 1422-0067 - wos: WOS:000539312100080 (11) - scopus: 2-s2.0-85084964055 (12)

11573/1359552 - 2020 - Unveiling the molecular basis of the noonan syndrome-causing mutation T42A of SHP2
Toto, A.; Malagrino, F.; Visconti, L.; Troilo, F.; Gianni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 461- - issn: 1661-6596 - wos: WOS:000515380000091 (6) - scopus: 2-s2.0-85077880233 (8)

11573/1445451 - 2020 - Understanding binding-induced folding by temperature jump
Toto, A.; Troilo, F.; Malagrino, F.; Gianni, S. - 02a Capitolo o Articolo
libro: Methods in Molecular Biology - (978-1-0716-0523-3; 978-1-0716-0524-0)

11573/1435303 - 2020 - Comparing the binding properties of peptides mimicking the envelope protein of sars-cov and sars-cov-2 to the pdz domain of the tight junction-associated pals1 protein
Toto, Angelo; Ma, Sana; Malagrinò, Francesca; Visconti, Lorenzo; Pagano, Livia; Stromgaard, Kristian; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000566781500001 (34) - scopus: 2-s2.0-85090470025 (38)

11573/1401188 - 2020 - Templated folding of intrinsically disordered proteins
Toto, Angelo; Malagrinò, Francesca; Visconti, Lorenzo; Troilo, Francesca; Pagano, Livia; Brunori, Maurizio; Jemth, Per; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 6586-6593 - issn: 0021-9258 - wos: WOS:000537685000027 (44) - scopus: 2-s2.0-85084721842 (45)

11573/1359561 - 2020 - The effect of proline cis‐trans isomerization on the folding of the C‐terminal SH2 domain from p85
Troilo, F.; Malagrino, F.; Visconti, L.; Toto, A.; Gianni, S. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 125- - issn: 1661-6596 - wos: WOS:000515378000125 (4) - scopus: 2-s2.0-85077263439 (5)

11573/1399303 - 2020 - Demonstration of binding induced structural plasticity in a sh2 domain
Visconti, Lorenzo; Toto, Angelo; Jarvis, James A.; Troilo, Francesca; Malagrinò, Francesca; De Simone, Alfonso; Gianni, Stefano - 01a Articolo in rivista
rivista: FRONTIERS IN MOLECULAR BIOSCIENCES (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-889X - wos: WOS:000537268200001 (6) - scopus: (0)

11573/1223718 - 2019 - Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents
Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R. - 01a Articolo in rivista
rivista: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 499-503 - issn: 1948-5875 - wos: WOS:000464767700019 (13) - scopus: 2-s2.0-85064264813 (13)

11573/1336097 - 2019 - Seeking allosteric networks in PDZ domains
Gautier, C; Laursen, L; Jemth, P; Gianni, S - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford : Oxford University Press) pp. - - issn: 1741-0134 - wos: WOS:000489553100002 (21) - scopus: 2-s2.0-85065500883 (22)

11573/1336091 - 2019 - A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins
Karlsson, E; Andersson, E; Dogan, J.; Gianni, S.; Jemth, P.; Camilloni, C. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 1230-1239 - issn: 1067-8816 - wos: WOS:000457879500014 (31) - scopus: 2-s2.0-85060586312 (32)

11573/1338512 - 2019 - Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Bufano, M.; Nalli, M.; Coluccia, A.; Orlando, V.; Canettieri, G.; Gianni, S.; Silvestri, R. - 04f Poster
congresso: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
libro: Abstract Book - ()

11573/1336078 - 2019 - Mapping the allosteric network within a SH3 domain
Malagrinò, F.; Troilo, F.; Bonetti, D.; Toto, A.; Gianni, S. - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000470075600028 (13) - scopus: 2-s2.0-85066618062 (16)

11573/1277788 - 2019 - Characterization of human frataxin missense variants in cancer tissues
Petrosino, Maria; Pasquo, Alessandra; Novak, Leonore; Toto, Angelo; Gianni, Stefano; Mantuano, Elide; Veneziano, Liana; Minicozzi, Velia; Pastore, Annalisa; Puglisi, Rita; Capriotti, Emidio; Chiaraluce, Roberta; Consalvi, Valerio - 01a Articolo in rivista
rivista: HUMAN MUTATION (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-14 - issn: 1059-7794 - wos: WOS:000485994200020 (14) - scopus: 2-s2.0-85070717849 (16)

11573/1336088 - 2019 - Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD
Toto, A.; Troilo, F.; Visconti, L.; Malagrinò, F.; Bignon, C.; Longhi, Sonia Rachele Agata; Gianni, S.; S, - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 255-261 - issn: 0003-9861 - wos: WOS:000525438900029 (6) - scopus: 2-s2.0-85069557296 (6)

11573/1336100 - 2019 - Understanding intramolecular crosstalk in an intrinsically disordered protein
Troilo, F.; Bonetti, D; Bignon, C; Longhi, S; Gianni, S - 01a Articolo in rivista
rivista: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. - - issn: 1554-8937 - wos: WOS:000461844100004 (15) - scopus: 2-s2.0-85061911824 (15)

11573/1336085 - 2019 - Structural characterization of an on-pathway intermediate and transition state in the folding of the N-terminal SH2 domain from SHP2
Visconti, L.; Malagrinò, F.; Gianni, S.; Toto, A. - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4769-4777 - issn: 1742-4658 - wos: WOS:000499718600012 (7) - scopus: 2-s2.0-85069838702 (8)

11573/1218458 - 2019 - Investigating the molecular basis of the aggregation propensity of the pathological d76n mutant of beta-2 microglobulin: role of the denatured state
Visconti, L; Malagrinò, F; Broggini, L; De Luca, Cmg; Moda, F; Gianni, S; Ricagno, S; Toto, A. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000459746500164 (5) - scopus: 2-s2.0-85060402058 (5)

11573/1253355 - 2019 - The kinetics of folding of the NSH2 domain from p85
Visconti, Lorenzo; Malagrinò, Francesca; Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 4058- - issn: 2045-2322 - wos: WOS:000460751700013 (9) - scopus: 2-s2.0-85062766339 (9)

11573/1218454 - 2018 - Modulation of measles virus NTAIL interactions through fuzziness and sequence features of disordered binding sites
Bignon, C; Troilo, F; Gianni, S; Longhi, S. - 01a Articolo in rivista
rivista: BIOMOLECULES (Basel: MDPI) pp. - - issn: 2218-273X - wos: WOS:000458051700008 (9) - scopus: 2-s2.0-85059235938 (11)

11573/1111610 - 2018 - How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein?
Bonetti, D; Troilo, F; Brunori, M; Longhi, S; Gianni, S. - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 1889-1894 - issn: 0006-3495 - wos: WOS:000432692800013 (31) - scopus: 2-s2.0-85046536598 (33)

11573/1140852 - 2018 - Mechanism of folding and binding of the n-terminal SH2 domain from SHP2
Bonetti, Daniela; Troilo, Francesca; Toto, Angelo; Travaglini-Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. - - issn: 1520-6106 - wos: WOS:000453488100016 (16) - scopus: 2-s2.0-85050853721 (18)

11573/1111606 - 2018 - Editorial overview: Folding and binding: In silico, in vitro and in cellula
Caflisch, A.; Gianni, S. - 01a Articolo in rivista
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. - - issn: 0959-440X - wos: WOS:000427218300001 (0) - scopus: 2-s2.0-85042263170 (0)

11573/1159784 - 2018 - Stability of an aggregation-prone partially folded state of human profilin-1 correlates with aggregation propensity
Edoardo Del Poggetto‡, ; Toto, Angelo; Chiara, Aloise‡; Francesco Di Piro‡, ; Ludovica, Gori‡; Malatesta, Francesco; Gianni, Stefano; X Fabrizio Chiti‡, ; And, X Francesco Bemporad‡1 - 01a Articolo in rivista
rivista: JOURNAL OF BIOLOGICAL CHEMISTRY (Bethesda, Md. : American Society for Biochemistry and Molecular Biology) pp. 10303-10313 - issn: 1083-351X - wos: WOS:000437096700028 (9) - scopus: 2-s2.0-85049653406 (9)

11573/1159789 - 2018 - A carboxylate to amide substitution that switches protein folds
Gianni, Stefano; Mccully, Michelle E.; Malagrinò, Francesca; Bonetti, Daniela; De Simone, Alfonso; Brunori, Maurizio; And Valerie Daggett, - 01a Articolo in rivista
rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 12795-12798 - issn: 1433-7851 - wos: WOS:000444941600032 (3) - scopus: 2-s2.0-85053053524 (3)

11573/1111524 - 2018 - Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins
Malgieri, G; D'abrosca, G; Pirone, L; Toto, A; Palmieri, M; Russo, L; Sciacca, Mfm; Tatè, R; Sivo, V; Baglivo, I; Majewska, R; Coletta, M; Pedone, Pv; Isernia, C; De Stefano, M; Gianni, S; Pedone, Em; Milardi, D; Fattorusso, R. - 01a Articolo in rivista
rivista: CHEMICAL SCIENCE (Cambridge : Royal Society of Chemistry, 2010-) pp. 3290-3298 - issn: 2041-6520 - wos: WOS:000431113300004 (17) - scopus: 2-s2.0-85044759336 (18)

11573/1071891 - 2018 - β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
Saponaro, Concetta; Sergio, Sara; Coluccia, Antonio; De Luca, Maria; La Regina, Giuseppe; Mologni, Luca; Famiglini, Valeria; Naccarato, Valentina; Bonetti, Daniela; Gautier, Candice Natacha Anna; Gianni, Stefano; Vergara, Daniele; Salzet, Michel; Fournier, Isabelle; Bucci, Cecilia; Silvestri, Romano; Gambacorti Passerini, Carlo; Maffia, Michele; Maria Luce Coluccia, Addolorata - 01a Articolo in rivista
rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3301-3316 - issn: 0950-9232 - wos: WOS:000435526600009 (18) - scopus: 2-s2.0-85044095990 (20)

11573/1111615 - 2018 - InSiDDe: A server for designing artificial disordered proteins
Schramm, A; Lieutaud, P.; Gianni, S.; Longhi, ; S., Bignon - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000424407200089 (5) - scopus: 2-s2.0-85039854886 (7)

11573/1140869 - 2018 - The folding mechanism of the SH3 domain from Grb2
Troilo, Francesca; Bonetti, Daniela; Camilloni, Carlo; Toto, Angelo; Longhi, Sonia; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL (American Chemical Society, Washington, D.C.) pp. - - issn: 1520-6106 - wos: WOS:000453488100022 (6) - scopus: 2-s2.0-85052317485 (7)

11573/1113877 - 2017 - Partner-mediated polymorphism of an intrinsically disordered protein
Bignon, C; Troilo, F; Gianni, S; Longhi, S. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (Elsevier Health Sciences:11830 Westline Industrial Drive:Saint Louis, MO 63146:(800)545-2522, EMAIL: customerservice@elsevier.com, Fax: (314)453-4535) pp. - - issn: 1089-8638 - wos: WOS:000439402200017 (12) - scopus: 2-s2.0-85039043862 (14)

11573/1014998 - 2017 - Analyzing the folding and binding steps of an intrinsically disordered protein by protein engineering
Bonetti, Daniela; Troilo, Francesca; Toto, Angelo; Brunori, Maurizio; Longhi, Sonia; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 3780-3786 - issn: 0006-2960 - wos: WOS:000406573100011 (25) - scopus: 2-s2.0-85025827155 (25)

11573/1014994 - 2017 - Regulation of the human phosphatase ptpn4 by the inter-domain linker connecting the pdz and the phosphatase domains
Caillet-Saguy, Célia; Toto, Angelo; Guerois, Raphael; Maisonneuve, Pierre; Di Silvio, Eva; Sawyer, Kristi; Gianni, Stefano; Wolff, Nicolas - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000407442500015 (10) - scopus: 2-s2.0-85031675178 (10)

11573/1014992 - 2017 - Addressing the role of the α-helical extension in the folding of the third PDZ domain from PSD-95
Gautier, Candice Natacha Anna; Visconti, Lorenzo; Per, Jemth; Gianni, Stefano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000412138800029 (10) - scopus: 2-s2.0-85030565452 (10)

11573/1014988 - 2017 - How fast is protein– ligand association?
Gianni, Stefano; Jemth, Per - 01a Articolo in rivista
rivista: TRENDS IN BIOCHEMICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 847-849 - issn: 0968-0004 - wos: WOS:000413441400002 (8) - scopus: 2-s2.0-85029226446 (9)

11573/1014985 - 2017 - Structural characterization of the early events in the nucleation− condensation mechanism in a protein folding process
Kukic, Predrag; Pustovalova, Yulia; Carlo, Camilloni; Gianni, Stefano; Korzhnev, Dmitry M.; Michele, Vendruscolo - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 6899-6910 - issn: 0002-7863 - wos: WOS:000416406202017 (0) - scopus: 2-s2.0-85019877885 (18)

11573/1014983 - 2017 - How order and disorder within paramyxoviral nucleoproteins and phosphoproteins orchestrate the molecular interplay of transcription and replication
Longhi1, Sonia; • Louis-Marie Bloyet3, 2; Gianni, Stefano; Gerlier, Denis - 01a Articolo in rivista
rivista: CELLULAR AND MOLECULAR LIFE SCIENCES (Basel: Birkhäuser 1997-) pp. - - issn: 1420-9071 - wos: WOS:000406500700003 (26) - scopus: 2-s2.0-85020622279 (30)

11573/1014977 - 2017 - Understanding the mechanism of binding between Gab2 and the C terminal SH3 domain from Grb2
Toto, Angelo; Bonetti, Daniela; De Simone, Alfonso; Gianni, Stefano - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 82344-82351 - issn: 1949-2553 - wos: WOS:000412683900060 (9) - scopus: 2-s2.0-85030863721 (9)

11573/954031 - 2017 - Understanding the role of phosphorylation in the binding mechanism of a PDZ domain
Toto, Angelo; Mattei, A.; Jemth, P.; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford : Oxford University Press) pp. 1-5 - issn: 1741-0134 - wos: WOS:000397129400001 (9) - scopus: 2-s2.0-85014750887 (11)

11573/956496 - 2017 - The folding pathway of the KIX domain
Troilo, Francesca; Bonetti, Daniela; Toto, Angelo; Visconti, L; Brunori, Maurizio; Longhi, S; Gianni, Stefano - 01a Articolo in rivista
rivista: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 1683-1690 - issn: 1554-8937 - wos: WOS:000403854000030 (6) - scopus: 2-s2.0-85020525210 (6)

11573/866165 - 2016 - Identification and structural characterization of an intermediate in the folding of the measles virus x domain
Bonetti, Daniela; Camilloni, Carlo; Visconti, Lorenzo; Longhi, Sonia; Brunori, Maurizio; Vendruscolo, Michele; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 10886-10892 - issn: 0021-9258 - wos: WOS:000377042600038 (18) - scopus: 2-s2.0-84969179536 (18)

11573/954032 - 2016 - Molecular medicine - to be or not to be
Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 33-46 - issn: 0301-4622 - wos: WOS:000378184800005 (3) - scopus: 2-s2.0-84969132884 (3)

11573/867523 - 2016 - Towards a structural biology of the hydrophobic effect in protein folding
Camilloni, Carlo; Bonetti, Daniela; Morrone, Angela; Giri, Rajanish; Dobson, Christopher M.; Brunori, Maurizio; Gianni, Stefano; Vendruscolo, Michele - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 28285- - issn: 2045-2322 - wos: WOS:000380327800001 (85) - scopus: 2-s2.0-84979738503 (92)

11573/862815 - 2016 - Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics?
Gianni, Stefano; Dogan, J.; Jemth, P. - 01a Articolo in rivista
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 18-24 - issn: 0959-440X - wos: WOS:000372681200005 (66) - scopus: 2-s2.0-84959288285 (68)

11573/931695 - 2016 - Protein folding: vexing debates on a fundamental problem
Gianni, Stefano; Jemth, - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 17-21 - issn: 0301-4622 - wos: WOS:000374625600003 (16) - scopus: 2-s2.0-84961652523 (18)

11573/849898 - 2016 - Fuzzy regions in an intrinsically disordered protein impair protein-protein interactions
Gruet, Antoine; Dosnon, Marion; Blocquel, David; Brunel, Joanna; Gerlier, Denis; Das, Rahul K.; Bonetti, Daniela; Gianni, Stefano; Fuxreiter, Monika; Longhi, Sonia; Bignon, Christophe - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. n/a-n/a - issn: 1742-464X - wos: WOS:000371071900001 (28) - scopus: 2-s2.0-84958945587 (28)

11573/953785 - 2016 - Activation barrier-limited folding and conformational sampling of a dynamic protein domain
Jakob Dogan, *; Toto, Angelo; Eva Andersson, §; Gianni, Stefano; Per Jemth, § - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 5289-5295 - issn: 0006-2960 - wos: WOS:000384038700010 (13) - scopus: 2-s2.0-84988672614 (13)

11573/860590 - 2016 - Molecular recognition by templated folding of an intrinsically disordered protein
Toto, Angelo; Camilloni, Carlo; Giri, Rajanish; Brunori, Maurizio; Vendruscolo, Michele; Gianni, Stefano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 21994- - issn: 2045-2322 - wos: WOS:000370796200001 (80) - scopus: 2-s2.0-84959441550 (82)

11573/931704 - 2016 - Mutational analysis of the binding-induced folding reaction of the mixed-lineage leukemia protein to the KIX domain.
Toto, Angelo; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 3957-3962 - issn: 0006-2960 - wos: WOS:000380297100011 (17) - scopus: 2-s2.0-84979527196 (17)

11573/931691 - 2016 - Ligand binding to the pdz domains of postsynaptic density protein 95
Toto, Angelo; Pedersen, Sw; Karlsson, Oa; Moran, Ge; Andersson, E; Chi, Cn; Strømgaard, K; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford : Oxford University Press) pp. 169-175 - issn: 1741-0134 - wos: WOS:000376351600002 (11) - scopus: 2-s2.0-84965026277 (11)

11573/782784 - 2015 - Understanding the effect of alternative splicing in the folding and function of the second pdz from protein tyrosine phosphatase-bl
Di Silvio, E; Toto, Angelo; Bonetti, Daniela; Morrone, A; Gianni, Stefano - 01a Articolo in rivista
rivista: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 9299- - issn: 2045-2322 - wos: WOS:000351277000008 (3) - scopus: 2-s2.0-84925396547 (3)

11573/862814 - 2015 - Frustration sculpts the early stages of protein folding
Di Silvio, Eva; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 10867-10869 - issn: 1433-7851 - wos: WOS:000360628500028 (11) - scopus: 2-s2.0-84940721459 (11)

11573/782780 - 2015 - Demonstration of a folding after binding mechanism in the recognition between the measles virus NTAIL and X domains
Dosnon, M; Bonetti, Daniela; Morrone, A; Erales, J; Di Silvio, E; Longhi, S; Gianni, Stefano - 01a Articolo in rivista
rivista: ACS CHEMICAL BIOLOGY (Washington, D.C. : American Chemical Society, c2006-) pp. 795-802 - issn: 1554-8937 - wos: WOS:000351558700018 (57) - scopus: 2-s2.0-84925346923 (60)

11573/554302 - 2014 - The kinetics of folding of frataxin.
Bonetti, Daniela; Toto, Angelo; Giri, R; Morrone, A; Sanfelice, D; Pastore, A; Temussi, P; Gianni, Stefano; Brunori, Maurizio - 01a Articolo in rivista
rivista: PHYSICAL CHEMISTRY CHEMICAL PHYSICS ([London, England] : Royal Society of Chemistry, 1999-) pp. 6391-6397 - issn: 1463-9084 - wos: WOS:000333119800009 (15) - scopus: 2-s2.0-84896367793 (17)

11573/658611 - 2014 - A complex equilibrium among partially unfolded conformations in monomeric transthyretin.
Conti, S; Li, X; Gianni, Stefano; Ghadami, Sa; Buxbaum, J; Cecchi, C; Chiti, F; Bemporad, F. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. - - issn: 0006-2960 - wos: WOS:000339226500008 (14) - scopus: 2-s2.0-84904331701 (12)

11573/577793 - 2014 - The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor
Di Silvio, Eva; Bonetti, Daniela; Toto, Angelo; A., Morrone; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford University Press) pp. 249-253 - issn: 1741-0126 - wos: WOS:000343042400001 (3) - scopus: 2-s2.0-84906230429 (3)

11573/554301 - 2014 - The binding mechanisms of intrinsically disordered proteins.
Dogan, J; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: PHYSICAL CHEMISTRY CHEMICAL PHYSICS ([London, England] : Royal Society of Chemistry, 1999-) pp. 6323-6331 - issn: 1463-9084 - wos: WOS:000333119800002 (106) - scopus: 2-s2.0-84896336036 (113)

11573/675273 - 2014 - Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.
Gianni, Stefano; Camilloni, C; Giri, R; Toto, Angelo; Bonetti, Daniela; Morrone, A; Sormanni, P; Brunori, Maurizio; Vendruscolo, M. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. - - issn: 0027-8424 - wos: WOS:000342350200039 (45) - scopus: 2-s2.0-84907573466 (45)

11573/658424 - 2014 - Distinguishing induced fit from conformational selection.
Gianni, Stefano; Dogan, J; Jemth, P. - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0301-4622 - wos: WOS:000336115700005 (121) - scopus: 2-s2.0-84898953700 (130)

11573/675274 - 2014 - Conserved nucleation sites reinforce the significance of Phi value analysis in protein-folding studies.
Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. - - issn: 1521-6543 - wos: WOS:000340575200001 (14) - scopus: 2-s2.0-84906347772 (14)

11573/658425 - 2014 - The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb.
Toto, Angelo; Giri, R; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000337669800012 (34) - scopus: 2-s2.0-84904215986 (33)

11573/554298 - 2013 - Functional role of transient conformations: Rediscovering "chronosteric effects" thirty years later.
Ascenzi, P; Gianni, Stefano - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 836-844 - issn: 1521-6543 - wos: WOS:000325027200004 (16) - scopus: 2-s2.0-84884923355 (16)

11573/554291 - 2013 - The folding pathway of a functionally competent C-terminal domain of nucleophosmin: protein stability and denatured state residual structure.
Chiarella, S; Federici, L; Di Matteo, A; Brunori, M; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 64-68 - issn: 0006-291X - wos: WOS:000320012900011 (6) - scopus: 2-s2.0-84878180768 (7)

11573/554294 - 2013 - Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations.
Eildal, Jn; Hultqvist, G; Balle, T; Stuhr Hansen, N; Padrah, S; Gianni, Stefano; Strømgaard, K; Jemth, P. - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 12998-13007 - issn: 0002-7863 - wos: WOS:000330163100020 (45) - scopus: 2-s2.0-84883679976 (43)

11573/554296 - 2013 - Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.
Giri, R; Morrone, A; Toto, Angelo; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 14942-14947 - issn: 0027-8424 - wos: WOS:000324125100038 (88) - scopus: 2-s2.0-84883780190 (91)

11573/554295 - 2013 - Energetic pathway sampling in a protein interaction domain.
Hultqvist, G; Haq, Sr; Punekar, As; Chi, Cn; Engström, Å; Bach, A; Strømgaard, K; Selmer, M; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: STRUCTURE (London: Current Biology.) pp. 1193-1202 - issn: 0969-2126 - wos: WOS:000321681600016 (35) - scopus: 2-s2.0-84879842193 (35)

11573/458690 - 2012 - Morphogenesis of a protein: folding pathways and the energy landscape
Brunori, Maurizio; Gianni, Stefano; Giri, Rajanish; Morrone, Angela; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 429-432 - issn: 0300-5127 - wos: WOS:000303624200022 (9) - scopus: 2-s2.0-84859311965 (9)

11573/488091 - 2012 - Interactions outside the Boundaries of the Canonical Binding Groove of a PDZ Domain Influence Ligand Binding
Celestine N., Chi; S., Raza Haq; Rinaldo, Serena; Jakob, Dogan; Cutruzzola', Francesca; Åke, Engstrom; Gianni, Stefano; Patrik, Lundstrom; Per, Jemth - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 8971-8979 - issn: 0006-2960 - wos: WOS:000310664200025 (17) - scopus: 2-s2.0-84868600086 (18)

11573/675050 - 2012 - Ligand binding by PDZ domains.
Chi, Cn; Bach, A; Strømgaard, K; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: BIOFACTORS (primo editore Oxford: IRL Press IOS Press:Nieuwe Hemweg 6B, 1013 BG Amsterdam Netherlands:011 31 20 6883355, EMAIL: r.tosendjojo@iospress.nl, INTERNET: http://www.iospress.nl, Fax: 011 31 20 6203419) pp. - - issn: 0951-6433 - wos: WOS:000310070100004 (59) - scopus: 2-s2.0-84867725616 (57)

11573/675251 - 2012 - A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein.
Gianni, Stefano; Morrone, A; Giri, R; Brunori, Maurizio - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. - - issn: 0006-291X - wos: WOS:000312431900001 (66) - scopus: 2-s2.0-84869218677 (67)

11573/486644 - 2012 - Folding pathways of proteins with increasing degree of sequence identities but different structure and function
Giri, Rajanish; Morrone, Angela; Travaglini Allocatelli, Carlo; Jemth, P; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 17772-17776 - issn: 1091-6490 - wos: WOS:000311149900024 (24) - scopus: 2-s2.0-84868122220 (24)

11573/675249 - 2012 - An expanded view of the protein folding landscape of PDZ domains.
Hultqvist, G; Pedersen, Sw; Chi, Cn; Strømgaard, K; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. - - issn: 0006-291X - wos: WOS:000306152000025 (11) - scopus: 2-s2.0-84860674621 (12)

11573/674850 - 2012 - Tolerance of protein folding to a circular permutation in a PDZ domain.
Hultqvist, G; Punekar, As; Morrone, A; Chi, Cn; Engström, A; Selmer, M; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000311821000173 (11) - scopus: 2-s2.0-84869796108 (13)

11573/675049 - 2012 - Reassessing the folding of the KIX domain: evidence for a two-state mechanism.
Morrone, A; Giri, R; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000310032900017 (1) - scopus: 2-s2.0-84867687230 (2)

11573/674852 - 2012 - GA/GB fold switching may modulate fatty acid transfer from human serum albumin to bacteria.
Polticelli, F; Caprari, S; Gianni, Stefano; Ascenzi, P. - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. - - issn: 1521-6543 - wos: WOS:000310345800004 (9) - scopus: 2-s2.0-84867783926 (9)

11573/427315 - 2011 - Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity.
Gianni, Stefano; S. R., Haq; Montemiglio, Linda Celeste; M. C., Jürgens; Å., Engström; C. N., Chi; Brunori, Maurizio; P., Jemth - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 27167-27175 - issn: 0021-9258 - wos: WOS:000293268700012 (56) - scopus: 2-s2.0-79961006047 (58)

11573/410615 - 2011 - Crystal structure of the apo form of human aromatic L-amino acid decarboxylase: an open conformation unveils novel insights into the mechanism of PLP addition to the apoenzymes of group II decarboxylases
Giardina, Giorgio; Montioli, R.; Gianni, Stefano; Cellini, B.; Paiardini, Alessandro; Voltattorni, Cb; Cutruzzola', Francesca - 04d Abstract in atti di convegno
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 263-263 - issn: 1742-464X - wos: WOS:000292333102058 (0) - scopus: (0)
congresso: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/426205 - 2011 - Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
Giardina, Giorgio; R., Montioli; Gianni, Stefano; B., Cellini; Paiardini, Alessandro; C., Borri Voltattorni; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 20514-20519 - issn: 0027-8424 - wos: WOS:000298289400055 (87) - scopus: 2-s2.0-84855517335 (85)

11573/408249 - 2011 - Addressing the folding pathway of two proteins with high sequence identity but different structure and function
Giri, Rajanish; Morrone, Angela; Travaglini Allocatelli, Carlo; Gianni, Stefano; Brunori, Maurizio - 04d Abstract in atti di convegno
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 107-107 - issn: 1742-4658 - wos: WOS:000292333101110 (0) - scopus: (0)

11573/675267 - 2011 - Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains
Haq, Sr; Chi, Cn; Bach, A; Dogan, J; Engström, Å; Hultqvist, G; Karlsson, Oa; Lundström, P; Strømgaard, K; Gianni, Stefano; Jemth, P.; Montemiglio, Linda Celeste - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 599-605 - issn: 0002-7863 - wos: WOS:000301084200096 (39) - scopus: 2-s2.0-84855656923 (39)

11573/468966 - 2011 - Investigating the structural plasticity of a cytochrome P450: 3D structure of EryK and binding to its physiological substrate and inhibitors
Montemiglio, L. C.; Vallone, Beatrice; Gianni, S.; Savino, C. - 04c Atto di convegno in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 120-120 - issn: 1742-4658 - wos: WOS:000292333101150 (0) - scopus: (0)
congresso: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/408262 - 2011 - Detection of an on-pathway intermediate in the folding of the small single-domain protein GB1
Morrone, Angela; Giri, Rajanish; Gianni, Stefano; Travaglini Allocatelli, Carlo; Brunori, Maurizio - 04d Abstract in atti di convegno
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 120-121 - issn: 1742-4658 - wos: WOS:000292333101152 (0) - scopus: (0)

11573/425119 - 2011 - GB1 Is Not a Two-State Folder: Identification and Characterization of an On-Pathway Intermediate
Morrone, Angela; Giri, Rajanish; Rudesh D, Toofanny; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Valerie, Daggett; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 2053-2060 - issn: 0006-3495 - wos: WOS:000296075800030 (28) - scopus: 2-s2.0-80054705419 (28)

11573/377442 - 2011 - The Denatured State Dictates the Topology of Two Proteins with Almost Identical Sequence but Different Native Structure and Function
Morrone, Angela; M. E., Mccully; P. N., Bryan; Brunori, Maurizio; V., Daggett; Gianni, Stefano; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 3863-3872 - issn: 0021-9258 - wos: WOS:000286653200067 (35) - scopus: 2-s2.0-79952805688 (35)

11573/401280 - 2011 - The folding mechanism of c-type cytochromes
Travaglini Allocatelli, Carlo; Gianni, Stefano; Brunori, Maurizio - 02a Capitolo o Articolo
libro: Protein Folding and Metal Ions - (9781439809648)

11573/359035 - 2010 - Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus
Di Matteo, Adele; Calosci, Nicoletta; Gianni, Stefano; Per, Jemth; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 2213-2221 - issn: 0887-3585 - wos: WOS:000279387400003 (20) - scopus: 2-s2.0-77955822694 (19)

11573/69778 - 2010 - Azole drugs trap cytochrome P450 EryK in alternative conformational states
Gianni S., Montemiglio Lc; Vallone, Beatrice; Carmelinda, Savino - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 9199-9206 - issn: 0006-2960 - wos: WOS:000283409100009 (16) - scopus: 2-s2.0-78049311396 (18)

11573/377436 - 2010 - Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain
Gianni, Stefano; Ivarsson, Y; De Simone, A; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Vendruscolo, M. - 01a Articolo in rivista
rivista: NATURE STRUCTURAL & MOLECULAR BIOLOGY (New York, N.Y. : Nature Pub. Group, [2004]-) pp. 1431-1437 - issn: 1545-9985 - wos: WOS:000284942200006 (46) - scopus: 2-s2.0-78649885501 (47)

11573/338221 - 2010 - Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants.
Giansanti, F; Di Leandro, L; Koutris, I; Pitari, G; Fabbrini, Ms; Lombardi, A; Flavell, Dj; Flavell, Su; Gianni, Stefano; Ippoliti, R. - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford University Press) pp. 61-68 - issn: 1741-0126 - wos: WOS:000274286200002 (11) - scopus: 2-s2.0-75649122575 (12)

11573/339026 - 2010 - The plastic energy landscape of protein folding: A triangular folding mechanism with an equilibrium intermediate for a small protein domain.
Haq, Sr; Juergens, Mc; Chi, Cn; Koh, Cs; Elfstrom, L; Selmer, M; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 18051-18059 - issn: 0021-9258 - wos: WOS:000278133400080 (20) - scopus: 2-s2.0-77952913083 (21)

11573/362851 - 2010 - Deciphering the folding transition state structure and denatured state properties of Nucleophosmin C-terminal domain
Scaloni, Flavio; Luca, Federici; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 5447-5452 - issn: 0027-8424 - wos: WOS:000275898300034 (32) - scopus: 2-s2.0-77950375373 (32)

11573/362280 - 2009 - Agitation and High Ionic Strength Induce Amyloidogenesis of a Folded PDZ Domain in Native Conditions
Alessandro, Sicorello; Silvia, Torrassa; Gemma, Soldi; Gianni, Stefano; Travaglini Allocatelli, Carlo; Niccolo, Taddei; Annalisa, Relini; Fabrizio, Chiti - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 2289-2298 - issn: 0006-3495 - wos: WOS:000266376700025 (30) - scopus: 2-s2.0-66149144761 (31)

11573/338217 - 2009 - A sequential binding mechanism in a PDZ domain.
Chi, Cn; Bach, A; Engström, A; Wang, H; Strømgaard, K; Gianni, Stefano; Jemth, P. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 7089-7097 - issn: 0006-2960 - wos: WOS:000268231800002 (41) - scopus: 2-s2.0-68049085520 (41)

11573/338215 - 2009 - A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases.
Federici, L; Masulli, M; Gianni, Stefano; Di Ilio, C; Allocati, N. - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 525-529 - issn: 0006-291X - wos: WOS:000265429200010 (7) - scopus: 2-s2.0-64049098665 (8)

11573/362269 - 2009 - Distinguishing between Smooth and Rough Free Energy Barriers in Protein Folding
Gianni, Stefano; Brunori, Maurizio; Per, Jemth; Mikael, Oliveberg; Mingjie, Zhang - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 11825-11830 - issn: 0006-2960 - wos: WOS:000272394000025 (11) - scopus: 2-s2.0-71549123381 (12)

11573/359076 - 2009 - Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.
Savino, C; Montemiglio, Linda Celeste; Sciara, G; Miele, Adriana Erica; Kendrew, Sg; Jemth, P; Gianni, S.; Vallone, Beatrice - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 29170-29179 - issn: 0021-9258 - wos: WOS:000270678900072 (64) - scopus: 2-s2.0-70350353089 (68)

11573/362859 - 2009 - Folding mechanism of the C-terminal domain of nucleophosmin: residual structure in the denatured state and its pathophysiological significance
Scaloni, Flavio; Gianni, S.; Federici, L.; Falini, B.; Brunori, Maurizio - 01a Articolo in rivista
rivista: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 2360-2365 - issn: 0892-6638 - wos: WOS:000268836700004 (28) - scopus: 2-s2.0-68849105588 (30)

11573/363844 - 2009 - Folding and stability of globular proteins and implications for function
Travaglini Allocatelli, Carlo; Ylva, Ivarsson; Per, Jemth; Gianni, Stefano - 01a Articolo in rivista
rivista: CURRENT OPINION IN STRUCTURAL BIOLOGY (Current Biology Limited:84 Theobalds Road, London WC1X 8RR United Kingdom:011 44 20 76114202, EMAIL: info@biomednet.com, INTERNET: http://www.biomednet.com, Fax: 011 44 20 76114479) pp. 3-7 - issn: 0959-440X - wos: WOS:000264282000002 (18) - scopus: 2-s2.0-60649096450 (19)

11573/362282 - 2009 - Engineered Symmetric Connectivity of Secondary Structure Elements Highlights Malleability of Protein Folding Pathways
Ylva, Ivarsson; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 11727-11733 - issn: 0002-7863 - wos: WOS:000269379400033 (23) - scopus: 2-s2.0-69049115135 (22)

11573/364902 - 2008 - Fast folding kinetics and stabilization of apo-cytochrome c
Borgia, Alessandro; Gianni, Stefano; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: FEBS LETTERS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1003-1007 - issn: 0014-5793 - wos: WOS:000257331400028 (7) - scopus: 2-s2.0-40349108420 (7)

11573/42934 - 2008 - “Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins
Calosci, Nicoletta; Chi C., N; Richter, B; Camilloni, C; Engström, A; Eklund, L; Travaglini Allocatelli, Carlo; Gianni, Stefano; Vendruscolo, M; Jemth, P. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 19240-19245 - issn: 0027-8424 - wos: WOS:000261706600041 (52) - scopus: 2-s2.0-58049200632 (54)

11573/363649 - 2008 - Folding and misfolding in a naturally occuring circularly permuted PDZ domain.
Ivarsson, Y; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 8954-8960 - issn: 0021-9258 - wos: WOS:000254465800024 (25) - scopus: 2-s2.0-44049089395 (25)

11573/366021 - 2008 - Mechanisms of protein folding.
Ivarsson, Y; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 721-728 - issn: 0175-7571 - wos: WOS:000256823000001 (15) - scopus: 2-s2.0-45849102407 (21)

11573/341354 - 2008 - Demonstration by burst phase analysis of a robust folding intermediate in the FF domain
Jemth, P; Johnson, C. M.; Gianni, Stefano; Fersht, A. R. - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford University Press) pp. - - issn: 1741-0126 - wos: (0) - scopus: 2-s2.0-40049101670 (10)

11573/42933 - 2008 - The folding process of acylphosphatase from Escherichia coli is remarkably accelerated by the presence of a disulfide bond.
Parrini, C; Bemporad, F; Baroncelli, A; Gianni, Stefano; Travaglini Allocatelli, Carlo; Kohn J., E; Ramazzotti, M; Chiti, F; Taddei, N. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 1107-1118 - issn: 0022-2836 - wos: WOS:000256815800013 (14) - scopus: 2-s2.0-44349147790 (16)

11573/358132 - 2008 - The folding pathway of an engineered circularly permuted PDZ domain
Y., Ivarsson; Travaglini Allocatelli, Carlo; V., Morea; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford University Press) pp. 155-160 - issn: 1741-0126 - wos: WOS:000253831300004 (16) - scopus: 2-s2.0-40049087433 (16)

11573/362837 - 2007 - A conserved folding mechanism for PDZ domains
Celestine N., Chi; Gianni, Stefano; Calosci, Nicoletta; Travaglini Allocatelli, Carlo; K., Engstrom; Per, Jemth - 01a Articolo in rivista
rivista: FEBS LETTERS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 1109-1113 - issn: 0014-5793 - wos: WOS:000245370600006 (44) - scopus: 2-s2.0-33847712992 (45)

11573/75154 - 2007 - A strategic protein in cytochrome c maturation: Three-dimensional structure of CcmH and binding to apocytochrome c
Di Matteo, Adele; Gianni, Stefano; Schinina', Maria Eugenia; Giorgi, Alessandra; Altieri, Fabio; Calosci, Nicoletta; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 27012-27019 - issn: 0021-9258 - wos: WOS:000249304900042 (34) - scopus: 2-s2.0-34848835185 (35)

11573/365111 - 2007 - Plasticity of the protein folding landscape: Switching between on- and off-pathway intermediates
Gianni, Stefano; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 172-176 - issn: 0003-9861 - wos: WOS:000250067700003 (4) - scopus: 2-s2.0-34548839354 (5)

11573/361948 - 2007 - A PDZ domain recapitulates a unifying mechanism for protein folding
Gianni, Stefano; C. D., Geierhaas; Calosci, Nicoletta; P., Jemth; G. W., Vuister; Travaglini Allocatelli, Carlo; M., Vendruscolo; Brunori, Maurizio - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 128-133 - issn: 0027-8424 - wos: WOS:000243456300025 (60) - scopus: 2-s2.0-33846115692 (65)

11573/340623 - 2007 - Mechanism of Na(+) binding to thrombin resolved by ultra-rapid kinetics.
Gianni, Stefano; Ivarsson, Y; Bah, A; Bush Pelic, L. A.; Di Cera, E. - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0301-4622 - wos: (0) - scopus: 2-s2.0-35648975465 (25)

11573/362577 - 2007 - Identification and characterization of protein folding intermediates
Gianni, Stefano; Y., Ivarrson; Per, Jemth; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 105-113 - issn: 0301-4622 - wos: WOS:000247582800002 (60) - scopus: 2-s2.0-34249691304 (76)

11573/340622 - 2007 - PDZ domains: folding and binding.
Jemth, P; Gianni, Stefano - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. - - issn: 0006-2960 - wos: (0) - scopus: 2-s2.0-34547643210 (145)

11573/362585 - 2007 - An on-pathway intermediate in the folding of a PDZ domain
Y., Ivarsson; Travaglini Allocatelli, Carlo; P., Jemth; Malatesta, Francesco; Brunori, Maurizio; Gianni, Stefano - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 8568-8572 - issn: 0021-9258 - wos: WOS:000245780300002 (39) - scopus: 2-s2.0-34247872879 (44)

11573/340395 - 2006 - Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain.
Chi, C. N.; Engstrom, Å; Gianni, Stefano; Larsson, M; Jemth, P. - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. - - issn: 0021-9258 - wos: (0) - scopus: 2-s2.0-33845995427 (44)

11573/358307 - 2006 - Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering
Gianni, Stefano; Tine, Walma; Arcovito, Alessandro; Calosci, Nicoletta; Bellelli, Andrea; Åke, Engstrom; Travaglini Allocatelli, Carlo; Brunori, Maurizio; Per, Jemth; Geerten W., Vuister - 01a Articolo in rivista
rivista: STRUCTURE (London: Current Biology.) pp. 1801-1809 - issn: 0969-2126 - wos: WOS:000242888600008 (96) - scopus: 2-s2.0-33845186553 (96)

11573/361974 - 2005 - The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism
Gianni, Stefano; A., Engstrom; M., Larsson; Calosci, Nicoletta; Malatesta, Francesco; L., Eklund; C. C., Ngang; Travaglini Allocatelli, Carlo; P., Jemth - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 34805-34812 - issn: 0021-9258 - wos: WOS:000232403900052 (79) - scopus: 2-s2.0-27144437020 (83)

11573/363884 - 2005 - Kinetic folding mechanism of PDZ2 from PTP-BL
Gianni, Stefano; Calosci, Nicoletta; J. M. A., Aelen; G. W., Vuister; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: PROTEIN ENGINEERING, DESIGN & SELECTION (Oxford University Press) pp. 389-395 - issn: 1741-0126 - wos: WOS:000231362100005 (52) - scopus: 2-s2.0-23944452163 (53)

11573/339832 - 2005 - The structure of the major transition state for folding of an FF domain from experiment and simulation.
Jemth, P; Day, R; Gianni, Stefano; Khan, F; Allen, M. D.; Daggett, V; Fersht, A. R. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. - - issn: 0022-2836 - wos: (0) - scopus: 2-s2.0-20444409471 (64)

11573/362597 - 2005 - An obligatory intermediate in the folding pathway of cyctochrome c552 from Hydrogenobacter thermophilus
Travaglini Allocatelli, Carlo; Gianni, Stefano; Dubey V., K; Borgia, Alessandro; Di Matteo, Adele; Bonivento, Daniele; Cutruzzola', Francesca; Bren K., L; Brunori, Maurizio - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 25729-25734 - issn: 0021-9258 - wos: WOS:000230207900053 (64) - scopus: 2-s2.0-21844453660 (67)

11573/339831 - 2005 - Simulation and Experiment Conspire to reveal Cryptic Intermediates and the Slide from Framework to Nucleation-Condensation Mechanism in the Folding of the Homeodomain Superfamily.
White G. W., N; Gianni, Stefano; Grossman J., G; Jemth, P; Fersht A., R; Daggett, V. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. - - issn: 0022-2836 - wos: (0) - scopus: (0)

11573/339829 - 2004 - Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation.
Jemth, P; Gianni, Stefano; Day, R; Li, B; Johnson C., M; Daggett, V; Fersht, A. R. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. - - issn: 1091-6490 - wos: (0) - scopus: 2-s2.0-2342655032 (101)

11573/364606 - 2004 - A common folding mechanism in the cytochrome c family
Travaglini Allocatelli, Carlo; Gianni, Stefano; Brunori, Maurizio - 01a Articolo in rivista
rivista: TRENDS IN BIOCHEMICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 535-541 - issn: 0968-0004 - wos: WOS:000224580300007 (47) - scopus: 2-s2.0-4644231179 (52)

11573/364932 - 2003 - Cytochrome c551 as a model system for protein folding
Brunori, Maurizio; Bigotti, Maria Giulia; Cutruzzola', Francesca; Gianni, Stefano; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: BIOPHYSICAL CHEMISTRY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 409-419 - issn: 0301-4622 - wos: WOS:000181883300037 (7) - scopus: 2-s2.0-0037438602 (7)

11573/339590 - 2003 - Unifying features in protein folding mechanisms.
Gianni, Stefano; Guydosh, N. R.; Khan, F; Caldas, T. D.; Mayor, U; White, G. W. N.; Demarco, M. L.; Daggett, V; Fersht, A. R. - 01a Articolo in rivista
rivista: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. - - issn: 1091-6490 - wos: (0) - scopus: 2-s2.0-0345255608 (226)

11573/339592 - 2003 - Structural insights in the folding of single domain proteins.
Gianni, Stefano; Mayor, U; Fersht, A. R. - 01a Articolo in rivista
rivista: ITALIAN JOURNAL OF BIOCHEMISTRY (Il Pensiero Scientifico) pp. - - issn: 0021-2938 - wos: (0) - scopus: (0)

11573/363340 - 2003 - Parallel pathways in cytochrome c551 folding
Gianni, Stefano; Travaglini Allocatelli, Carlo; Cutruzzola', Francesca; Brunori, Maurizio; Ramachandra Shastry M., C; Roder, H. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 1145-1152 - issn: 0022-2836 - wos: WOS:000184299000020 (48) - scopus: 2-s2.0-0037675765 (49)

11573/339591 - 2003 - The kinetic pathway of folding of barnase.
Khan, F; Chuang J., I; Gianni, Stefano; Fersht, A. R. - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. - - issn: 0022-2836 - wos: WOS:000185794700013 (74) - scopus: 2-s2.0-0141457507 (76)

11573/127664 - 2003 - Exploring the cytochrome c folding: cyt c552 from Thermus Thermopilus folds through and on-pathway intermediate
Travaglini Allocatelli, Carlo; Gianni, Stefano; Morea, V.; Tramontano, Anna; Soulimane, T.; Brunori, Maurizio - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 41136-41140 - issn: 0021-9258 - wos: WOS:000185847200089 (39) - scopus: 2-s2.0-0142135083 (39)

11573/364393 - 2001 - Fast coordination changes in cytochrome c do not necessarily imply folding
A., Arcovito; Gianni, Stefano; Brunori, Maurizio; Travaglini Allocatelli, Carlo; Bellelli, Andrea - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 41073-41078 - issn: 0021-9258 - wos: WOS:000171925600094 (27) - scopus: 2-s2.0-0035798650 (30)

11573/42403 - 2001 - Refolding kinetics of cyt c551 from Pseudomonas aeruginosa reveals a mechanistic difference between guanidine and urea.
Gianni, Stefano; Brunori, Maurizio; Travaglini Allocatelli, Carlo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. 1685-1688 - issn: 0961-8368 - wos: WOS:000169984100022 (25) - scopus: 2-s2.0-0034917762 (25)

11573/393231 - 2001 - Snapshots of protein folding. A study on the multiple transition state pathway of cytochrome c(551) from Pseudomonas aeruginosa.
Gianni, Stefano; Travaglini Allocatelli, Carlo; Cutruzzola', Francesca; Bigotti, Mg; Brunori, Maurizio - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 1177-1187 - issn: 0022-2836 - wos: WOS:000169586000013 (29) - scopus: 2-s2.0-0035933343 (33)

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