SILVIA PERNA

PhD Student

PhD program:: XL
email: silvia.perna@uniroma1.it
building: V clinica medica, Policlinico Umberto I
room: L07




supervisor: Claudia Carissimi
advisor: Laura Stronati

Research: Role of the transcription factor ZNF281 in controlling cancer progression and invasion

WORK EXPERIENCE:
1 November 2024 - Present PhD in Human Biology and Medical Genetics
Department of Experimental Medicine, University of Rome ‘La Sapienza’ (RM)

1 June 2024 – 31 October 2024 JUNIOR Scholarship
Department of Molecular Medicine, University of Rome ‘La Sapienza’ (RM)
JUNIOR Scholarship as part of the FIRB 2011 funded project entitled: ‘Multiomics and machine learning to predict response to drug therapies in paediatric Eosinophilic Oesophagitis’.

1 June 2023 – 31 May 2024 Category B Type I Research Grant – SSD BIO12
Department of Molecular Medicine, University of Rome ‘La Sapienza’ (RM)
Research Grant Project: ‘Multiomics and machine learning to predict response to drug therapies in paediatric eosinophilic oesophagitis’.
● Molecular and cellular biology techniques: cell cultures, optical microscopy, RNA interference, Western Blot, PCR, Real Time PCR;
● CRISPR/CAS9 methodology

March 2022 – October 2022 Curricular internship
I.R.C.C.S. Policlinico San Matteo Foundation, Pavia (PV)
Thesis internship aimed at writing a paper entitled: “Development of an alginate and gelatin-based hydrogel suitable for the proliferation of porcine mesenchymal stromal cells”.


● Applied cell biology techniques: isolation, cultivation and expansion of mesenchymal stromal cells and their derivatives;
● Mesenchymal cell-based scaffolds;
● Study of the functional activities of mesenchymal stromal cells and their derivatives (nanoparticles).

July 2019 – September 2019 Curricular internship
Buonarroti Diagnostic Centre, Civitavecchia (RM)
The experience trained me in the various areas of an anatomical pathology laboratory: cytological, histological, immunohistochemical.
● Diagnostics and laboratory analysis: haematology slide staining; microscopic reading of urine samples and their chemical-physical analysis; immunoenzymatic assays for the processing of oropharyngeal/genital swabs; sperm analysis.

EDUCATION AND TRAINING:
March 2025 Registration in the Register of Biologists of Lazio and Abruzzo

March 2024 Qualification to practise as a biologist
University of Bari Aldo Moro (BA)

December 2022 Master's Degree in Medical Biotechnology, 110 cum laude
Faculty of Pharmacy and Medicine, University of Pavia (PV)
Thesis: 'Development of an alginate and gelatin-based hydrogel suitable for the
proliferation of porcine mesenchymal stromal cells'

September 2020 Bachelor's Degree in Biotechnology, 109/110
Department for Innovation in Biological, Agri-Food and Forestry Systems at the University of Tuscia (VT)
Thesis: ‘Biotechnological production of molecules of therapeutic interest’

July 2016 Scientific High School Diploma
Galileo Galilei Scientific High School, Santa Marinella (RM)



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L'elenco e le finalità delle attività intraprese dalla Sapienza sono descritte nella pagina dedicata Sapienza per il Pnrr.

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