SERENA RINALDO

Professore associato


email: serena.rinaldo@uniroma1.it
telefono: 0649910713
edificio: cu027
stanza: 312, t2

Posizione attuale: Professore associato (05/E2 - SSD BIO/11) Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli' - SAPIENZA, Università di Roma. FORMAZIONE E CARRIERA 2016-2019 Ricercatore con tenure track SAPIENZA, Università di Roma 2015-2016 Post-doctoral fellowship (1 year) SAPIENZA, Università di Roma 2012-2015 Ricercatore (full-time, art. 24 c.3-a L. 240/10) SAPIENZA, Università di Roma 2009-2012 Post-doctoral fellowship SAPIENZA, Università di Roma 2007-to date Docente presso la Facoltà di Farmacia e Medicina di SAPIENZA, Università di Roma 2005-2008 Post-doctoral research contract SAPIENZA, University of Rome 2006 PhD -Biochimica (Relatore Prof. M. Brunori) SAPIENZA, Università di Roma 2002 Laurea cum laude in Biologia SAPIENZA, Università di Roma INCARICHI E ABILITAZIONI 2021 Co Task-leader for End-users training schools and short courses – MOSBRI H2020-INFRAIA 2018 Abilitazione Scientifica Nazionale in Biochimica (05/E1 - SSD BIO/10) - Professore Prima Fascia 2017 Abilitazione Scientifica Nazionale in Biochimica (05/E1 - SSD BIO/10) - Professore Seconda Fascia 2015 Abilitazione Scientifica Nazionale in Biologia Molecolare (05/E2 - SSD BIO/11) - Professore Seconda Fascia 2012 MIUR - Coordinatore e PI del progetto FIRB-FUTURO IN RICERCA 2010 RBFR10LHD1 2007 ESTACIÓN EXPERIMENTAL DEL ZAIDÍN- Granada (E) Short term scientific mission aboard finanziata da European COST Action 856 2004 Free University of Amsterdam (NL) Short term scientific mission aboard finanziata da European COST Action 856 e Società Italiana di Biochimica e Biologia Molecolare (SIB) ATTIVITÀ DI RICERCA L’attività scientifica è incentrata sull’analisi dei meccanismi molecolari che controllano l’attività di proteine coinvolte in processi biologici cruciali per l’omeostasi e il mantenimento della cellula al fine di chiarire i meccanismi molecolari che portano a condizioni patologiche. L’analisi della relazione struttura-funzione di proteine chiave in processi cellulari complessi e importanti, quali le infezioni croniche o i tumori, è condotta attraverso un approccio multidisciplinare che vede l’integrazione della biochimica, della biologia molecolare e della biofisica molecolare. La realizzazione di questi obiettivi è stata possibile grazie all’esperienza specifica acquisita nella biochimica di proteine (enzimi e fattori di trascrizione) redox, coinvolte nella sintesi e percezione dell’ossido nitrico, nella trasduzione del segnale e nel riconoscimento di acidi nucleici e nutrienti. L'approccio metodologico prevede studi di ingegneria proteica, cinetica rapida, spettroscopia e tecniche di biofisica molecolare quali la microcalorimetria per lo studio di interazioni molecolari. FINANZIAMENTI COME PI: 2023-2025 Nucleotide-based tools to inhibit nanoRNA degradation in cells: is REXO2 a novel target in cancer therapy? 2022KC3X9L PRIN “finanziato dall’Unione europea – Next Generation EU” € 184921 2022 FEMS Meeting Organizer Grant (25th European Nitrogen cycle meeting, FEMS-GO-2021-048) Federation of European Microbiological Societies € 5000 2021 25th European Nitrogen Cycle meeting. CC12117A599C4755 Sapienza - Università di Roma € 4300 2020-2023 -Sapienza Università di Roma - Tuning c-di-GMP in Pseudomonas aeruginosa to control biofilm dispersion: molecular mechanism of signal transduction in response to environmental cues. RM120172A7AD98EB (€ 33787) 2019-2021 - Istituto Pasteur - Fondazione Cenci Bolognetti -Sensing arginine through the Venus Fly Trap domain to control c-di-GMP levels in Pseudomonas aeruginosa: molecular mechanism and metabolic effects of signal transduction (€ 40000) 2017-2020 Sapienza - Universita' di Roma - Nucleotide signalling in prokaryotes and eukaryotes: from proteins to metabolic networks (€ 8000) 2017 MIUR- Finanziamento delle attività base di ricerca (€ 3000) 2012-2016 MIUR - FIRB-FUTURO IN RICERCA 2010 - BIOCHEMISTRY AND MOLECULAR BIOLOGY OF CYCLIC DI-GMP AND QUORUM SENSING SIGNALING PATHWAYS IN PSEUDOMONAS AERUGINOSA. RBFR10LHD1; Coordinator of two research units (€ 453300). ALTRO • Responsabile della Facility ProFacT, Protein FActory Training Lab in Sapienza • Data Analyst in the HypACB facility for oxygen-controlled respiration measurement.

Produzione scientifica

11573/1702420 - 2024 - Beyond the barrier: the immune-inspired pathways of tumor extravasation
Di Russo, S.; Liberati, F. R.; Riva, A.; Di Fonzo, F.; Macone, A.; Giardina, G.; Arese, M.; Rinaldo, S.; Cutruzzola, F.; Paone, A. - 01g Articolo di rassegna (Review)
rivista: CELL COMMUNICATION AND SIGNALING (BioMed Central, London) pp. 104- - issn: 1478-811X - wos: WOS:001160608800001 (0) - scopus: 2-s2.0-85184788152 (1)

11573/1711799 - 2024 - Biliverdin reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
Lanzillotta, Chiara; Tramutola, Antonella; Lanzillotta, Simona; Greco, Viviana; Pagnotta, Sara; Sanchini, Caterina; Di Angelantonio, Silvia; Forte, Elena; Rinaldo, Serena; Paone, Alessio; Cutruzzolà, Francesca; Cimini, Flavia Agata; Barchetta, Ilaria; Cavallo, Maria Gisella; Urbani, Andrea; Butterfield, D Allan; Di Domenico, Fabio; Paul, Bindu D; Perluigi, Marzia; Duarte, Joao M N; Barone, Eugenio - 01a Articolo in rivista
rivista: REDOX BIOLOGY (Amsterdam : Elsevier) pp. - - issn: 2213-2317 - wos: (0) - scopus: 2-s2.0-85195097821 (0)

11573/1711262 - 2024 - AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach
Rosignoli, Serena; Lustrino, Elisa; Conci, Alessio; Fabrizi, Alessandra; Rinaldo, Serena; Latella, Maria&Nbsp;; Carmela, ; Enzo, Elena; Prosseda, Gianni; De Rosa, Laura; De Luca, Michele; Paiardini, Alessandro - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. - - issn: 0305-1048 - wos: WOS:001230689400001 (0) - scopus: (0)

11573/1709178 - 2024 - Exploring the Metabolic Response of Pseudomonas putida to L-arginine
Scribani-Rossi, Chiara; Molina-Henares, María Antonia; Espinosa-Urgel, Manuel; Rinaldo, Serena - 02a Capitolo o Articolo
libro: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY - ()

11573/1714195 - 2024 - Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
Spizzichino, Sharon; Di Fonzo, Federica; Marabelli, Chiara; Tramonti, Angela; Chaves-Sanjuan, Antonio; Parroni, Alessia; Boumis, Giovanna; Liberati, Francesca Romana; Paone, Alessio; Montemiglio, Linda Celeste; Ardini, Matteo; Jakobi, Arjen J.; Bharadwaj, Alok; Swuec, Paolo; Tartaglia, Gian Gaetano; Paiardini, Alessandro; Contestabile, Roberto; Mai, Antonello; Rotili, Dante; Fiorentino, Francesco; Macone, Alberto; Giorgi, Alessandra; Tria, Giancarlo; Rinaldo, Serena; Bolognesi, Martino; Giardina, Giorgio; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: MOLECULAR CELL (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. - - issn: 1097-2765 - wos: (0) - scopus: (0)

11573/1714654 - 2024 - Targeting mitochondrial homeostasis with small molecules: from environmental contaminants to inhibitors of nucleotide re-cycling
Sprovera, Benedetta; Commisso, Manuela; Pacelli, Maddalena; Fagiani, Stefano; Paone, Alessio; Cutruzzola, Francesca; Arese, Marzia; Rinaldo, Serena - 04f Poster
congresso: 48th FEBS CONGRESS (Milano, Italy)
libro: 48th FEBS CONGRESS - ()

11573/1698285 - 2023 - 3-O-Methyltolcapone and its lipophilic analogues are potent inhibitors of transthyretin amyloidogenesis with high permeability and low toxicity
Poonsiri, Thanalai; Dell'accantera, Davide; Loconte, Valentina; Casnati, Alessandro; Cervoni, Laura; Arcovito, Alessandro; Benini, Stefano; Ferrari, Alberto; Cipolloni, Marco; Cacioni, Elisa; De Franco, Francesca; Giacche', Nicola; Rinaldo, Serena; Folli, Claudia; Sansone, Francesco; Berni, Rodolfo; Cianci, Michele - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:001140637500001 (0) - scopus: (0)

11573/1689849 - 2023 - Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa.
Scribani Rossi, C; Eckartt, K; Scarchilli, E; Angeli, S; Price-Whelan, A; Di Matteo, A; Chevreuil, M; Raynal, B; Arcovito, A; Giacon, N; Fiorentino, F; Rotili, D; Mai, A; Espinosa-Urgel, M; Cutruzzola', F; Dietrich, Lep; Paone, A; Paiardini, A; Rinaldo, S - 01a Articolo in rivista
rivista: MICROBIOLOGICAL RESEARCH (Urban & Fischer Verlag Jena:Postfach 100537, D-07705 Jena Germany:011 49 3641 626430, EMAIL: journals@urbanfischer.de, INTERNET: http://www.urbanfischer.de, Fax: 011 49 3641 626500) pp. 127498- - issn: 0944-5013 - wos: WOS:001097478000001 (0) - scopus: 2-s2.0-85173505521 (0)

11573/1689850 - 2023 - Exploring innovative approaches to isolate a one-component c-di-GMP transducer: A pilot study
Scribani Rossi, C; Parisi, G; Paiardini, A; Rinaldo, S - 02a Capitolo o Articolo
libro: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY - ()

11573/1689461 - 2023 - The phosphodiesterase RmcA contributes to the adaptation of Pseudomonas putida to l-arginine
Scribani-Rossi, Chiara; Antonia Molina-Henares, María; Angeli, Simone; Cutruzzola, Francesca; Paiardini, Alessandro; Espinosa-Urgel, Manuel; Rinaldo, Serena - 01a Articolo in rivista
rivista: FEMS MICROBIOLOGY LETTERS ([S.l.] : Blackwell S.l.] : Elsevier Science) pp. - - issn: 1574-6968 - wos: WOS:001046826600003 (1) - scopus: 2-s2.0-85168750549 (1)

11573/1666833 - 2022 - Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms
Cappello, Angela; Mancini, Mara; Madonna, Stefania; Rinaldo, Serena; Paone, Alessio; Scarponi, Claudia; Belardo, Antonio; Zolla, Lello; Zuccotti, Alessandro; Panatta, Emanuele; Pallotta, Sabatino; Annicchiarico-Petruzzelli, Margherita; Albanesi, Cristina; Cutruzzola', Francesca; Wang, Lu; Jia, Wei; Melino, Gerry; Candi, Eleonora - 01a Articolo in rivista
rivista: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000905194200011 (7) - scopus: 2-s2.0-85144193681 (6)

11573/1575071 - 2022 - A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins
Cutruzzolà, Francesca; Paiardini, Alessandro; Scribani Rossi, Chiara; Spizzichino, Sharon; Paone, Alessio; Giardina, Giorgio; Rinaldo, Serena - 01g Articolo di rassegna (Review)
rivista: COORDINATION CHEMISTRY REVIEWS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 214228- - issn: 0010-8545 - wos: WOS:000706196900003 (3) - scopus: 2-s2.0-85115933139 (3)

11573/1651824 - 2022 - Riboregulation as a new player in the control of cellular metabolism: clues from the cryo-EM structure of serine hydroxymethyltransferase-RNA complex
Giardina, Giorgio; Spizzichino, Sharon; Marabelli, Chiara; Di Fonzo, Federica; Tramonti, Angela; Parroni, Alessia; Contestabile, Roberto; Chaves, Antonio; Rinaldo, Serena; Bolognesi, Martino; Cutruzzola', Francesca - 04d Abstract in atti di convegno
congresso: 17th SIBBM Seminar Frontiers in Molecular Biology - The RNA World 3.0 Abstracts (Roma)
libro: Abstract Book - ()

11573/1641216 - 2022 - Nutrient sensing and biofilm modulation: the example of L-arginine in Pseudomonas
Scribani Rossi, C; Barrientos-Moreno, L.; Paone, A.; Cutruzzola', F.; Paiardini, A.; Espinosa-Urgel, M.; Rinaldo, S. - 01g Articolo di rassegna (Review)
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 4386- - issn: 1661-6596 - wos: WOS:000785501700001 (19) - scopus: 2-s2.0-85128190924 (22)

11573/1584599 - 2022 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 1625-1649 - issn: 1742-464X - wos: WOS:000717476400001 (1) - scopus: 2-s2.0-85118844105 (2)

11573/1673938 - 2022 - Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome
Turco, E. M.; Giovenale, A. M. G.; Sireno, L.; Mazzoni, M.; Cammareri, A.; Marchioretti, C.; Goracci, L.; Di Veroli, A.; Marchesan, E.; D'andrea, D.; Falconieri, A.; Torres, B.; Bernardini, L.; Magnifico, M. C.; Paone, A.; Rinaldo, S.; Della Monica, M.; D'arrigo, S.; Postorivo, D.; Nardone, A. M.; Zampino, G.; Onesimo, R.; Leoni, C.; Caicci, F.; Raimondo, D.; Binda, E.; Trobiani, L.; De Jaco, A.; Tata, A. M.; Ferrari, D.; Cutruzzola, F.; Mazzoccoli, G.; Ziviani, E.; Pennuto, M.; Vescovi, A. L.; Rosati, J. - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000886207500001 (2) - scopus: 2-s2.0-85142392229 (2)

11573/1654701 - 2022 - Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I-Mediated Antiviral Responses in Primary Human Dendritic Cells
Zevini, Alessandra; Palermo, Enrico; Di Carlo, Daniele; Alexandridi, Magdalini; Rinaldo, Serena; Paone, Alessio; Cutruzzola, Francesca; Etna, Marilena P; Coccia, Eliana M; Olagnier, David; Hiscott, John - 01a Articolo in rivista
rivista: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (Lausanne : Frontiers Media SA, 2011-) pp. 1-14 - issn: 2235-2988 - wos: WOS:000841727700001 (4) - scopus: 2-s2.0-85135279463 (6)

11573/1553790 - 2021 - The emerging role of amino acids of the brain microenvironment in the process of metastasis formation
Cutruzzola', Francesca; Bouzidi, Amani; Liberati, Francesca Romana; Spizzichino, Sharon; Boumis, Giovanna; Macone, Alberto; Rinaldo, Serena; Giardina, Giorgio; Paone, Alessio - 01g Articolo di rassegna (Review)
rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000666104500001 (4) - scopus: 2-s2.0-85107408621 (4)

11573/1609024 - 2021 - Structure and metal-binding properties of PA4063, a novel player in periplasmic zinc trafficking by Pseudomonas aeruginosa
Fiorillo, A.; Battistoni, A.; Ammendola, S.; Secli, V.; Rinaldo, S.; Cutruzzola, F.; Demitri, N.; Ilari, A. - 01a Articolo in rivista
rivista: ACTA CRYSTALLOGRAPHICA. SECTION D, STRUCTURAL BIOLOGY (Chester : International Union of Crystallography, 2016-) pp. 1401-1410 - issn: 2059-7983 - wos: WOS:000714429000007 (6) - scopus: 2-s2.0-85118921269 (6)

11573/1492549 - 2021 - Studying ggdef domain in the act: Minimize conformational frustration to prevent artefacts
Mantoni, F.; Scribani Rossi, C.; Paiardini, A.; Di Matteo, A.; Cappellacci, L.; Petrelli, R.; Ricciutelli, M.; Paone, A.; Cutruzzola', F.; Giardina, G.; Rinaldo, S. - 01a Articolo in rivista
rivista: LIFE (Basel: MDPI) pp. 1-13 - issn: 2075-1729 - wos: WOS:000610391100001 (4) - scopus: 2-s2.0-85100221529 (4)

11573/1551300 - 2021 - Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments
Monti, Michele; Guiducci, Giulia; Paone, Alessio; Rinaldo, Serena; Giardina, Giorgio; Liberati, Francesca Romana; Cutruzzolá, Francesca; Tartaglia, Gian Gaetano - 01a Articolo in rivista
rivista: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (Göteborg : Chalmers University of Technology, 2011-) pp. 3034-3041 - issn: 2001-0370 - wos: WOS:000684817100004 (7) - scopus: 2-s2.0-85106619221 (8)

11573/1577022 - 2021 - Determining folding and binding properties of the C-terminal SH2 domain of SHP2
Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
rivista: PROTEIN SCIENCE (Cambridge University Press / New York:40 West 20th Street:New York, NY 10011:(800)872-7423, (212)924-3900, EMAIL: journals_subscriptions@cup.org, INTERNET: http://www.journals.cambridge.org, Fax: (212)691-3239) pp. - - issn: 0961-8368 - wos: WOS:000705532500001 (5) - scopus: 2-s2.0-85116539527 (6)

11573/1551305 - 2021 - Importance of amino acids in brain parenchyma invasion by cancer cells
Paone, Alessio; Bouzidi, Amani; Rinaldo, Serena; Giardina, Giorgio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: ONCOSCIENCE (Impact Journals LLC -) pp. 47-49 - issn: 2331-4737 - wos: (0) - scopus: (0)

11573/1558512 - 2021 - L- Arginine in Pseudomonas aeruginosa controls c-di-GMP levels and biofilm formation
Scribani Rossi, Chiara; Mantoni, Federico; Giardina, Giorgio; Paiardini, Alessandro; Di Matteo, Adele; Cutruzzola', Francesca; Rinaldo, Serena - 04d Abstract in atti di convegno
congresso: efb 2021 (online)
libro: efb 2021 - ()

11573/1558505 - 2021 - Signal transduction and c-di-GMP second messenger: novel tools to investigare the mechanism of nutrient sensing.
Scribani Rossi, Chiara; Parisi, Giacomo; Giardina, Giorgio; Cutruzzola', Francesca; Paiardini, Alessandro; Rinaldo, Serena - 04d Abstract in atti di convegno
congresso: WEBPRO - Proteins on the Web 2021. (online)
libro: WEBPRO - Proteins on the Web 2021. - ()

11573/1553985 - 2021 - Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Tramonti, Angela; Paiardini, Alessandro; Contestabile, Roberto; Pochetti, Giorgio; Rinaldo, Serena; Paone, Alessio; Giardina, Giorgio; Cutruzzola', Francesca - 04d Abstract in atti di convegno
congresso: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research (online)
libro: 16th SIBBM Seminar Frontiers in Molecular Biology Frontiers in metabolic research Abstracts - ()

11573/1558518 - 2021 - Structural clues of Serine hidroxymethyltransferase (SHMT) riboregulation
Spizzichino, Sharon; Marabelli, Chiara; Chaves Sanjuan, Antonio; Swuec, Paolo; Montemiglio, Linda Celeste; Ardini, Matteo; Rinaldo, Serena; Paone, Alessio; Boumis, Giovanna; Giardina, Giorgio; Bolognesi, Martino; Cutruzzola', Francesca - 04d Abstract in atti di convegno
congresso: 2nd Italian Crystallographic Association Biological MacroMolecules Group Meeting (online)
libro: 2nd Italian Crystallographic Association Biological MacroMolecules Group Meeting - ()

11573/1532739 - 2021 - High-fat diet leads to reduced protein o-glcnacylation and mitochondrial defects promoting the development of Alzheimer’s disease signatures
Zuliani, I.; Lanzillotta, C.; Tramutola, A.; Barone, E.; Perluigi, M.; Rinaldo, S.; Paone, A.; Cutruzzola', F.; Bellanti, F.; Spinelli, M.; Natale, F.; Fusco, S.; Grassi, C.; Di Domenico, F. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000638633700001 (18) - scopus: 2-s2.0-85103489586 (19)

11573/1463758 - 2020 - Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
Bouzidi, Amani; Magnifico, Maria Chiara; Paiardini, Alessandro; Macone, Alberto; Boumis, Giovanna; Giardina, Giorgio; Rinaldo, Serena; Liberati, Francesca Romana; Lauro, Clotilde; Limatola, Cristina; Lanzillotta, Chiara; Tramutola, Antonella; Perluigi, Marzia; Sgarbi, Gianluca; Solaini, Giancarlo; Baracca, Alessandra; Paone, Alessio; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000595956300001 (10) - scopus: 2-s2.0-85096677891 (10)

11573/1648069 - 2020 - Structure and function of HD-GYP phosphodiesterases
Rinaldo, S.; Paiardini, A.; Paone, A.; Cutruzzola', F.; Giardina, G. - 02a Capitolo o Articolo
libro: Microbial Cyclic Di-Nucleotide Signaling - (978-3-030-33307-2; 978-3-030-33308-9)

11573/1244108 - 2019 - The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism
Guiducci, Giulia; Paone, Alessio; Tramonti, Angela; Giardina, Giorgio; Rinaldo, Serena; Bouzidi, Amani; Magnifico, Maria C; Marani, Marina; Menendez, Javier A; Fatica, Alessandro; Macone, Alberto; Armaos, Alexandros; Tartaglia, Gian G; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. 1-16 - issn: 0305-1048 - wos: WOS:000473754300036 (25) - scopus: 2-s2.0-85067847112 (26)

11573/1330057 - 2019 - Fractalkine Modulates Microglia Metabolism in Brain Ischemia
Lauro, C.; Chece, G.; Monaco, L.; Antonangeli, F.; Peruzzi, G.; Rinaldo, S.; Paone, A.; Cutruzzola, F.; Limatola, C. - 01a Articolo in rivista
rivista: FRONTIERS IN CELLULAR NEUROSCIENCE (Lausanne (PO Box 110, 1015) : Frontiers Research Foundation, 2007-) pp. - - issn: 1662-5102 - wos: WOS:000485730400001 (52) - scopus: 2-s2.0-85072834928 (52)

11573/1330042 - 2019 - Linking infection and prostate cancer progression: Toll-like receptor3 stimulation rewires glucose metabolism in prostate cells
Magnifico, M. C.; Macone, A.; Marani, M.; Bouzidi, A.; Giardina, G.; Rinaldo, S.; Cutruzzola, F.; Paone, A. - 01a Articolo in rivista
rivista: ANTICANCER RESEARCH (Kapandriti: International Institute of Anticancer Research, 1995 Earliest publisher: Καπανδρίτι: Ιωάννης Γ. Δεληνάσιος, 1981-1995 Kapandriti: Iōannīs G. Delīnasios, 1981-1995) pp. 5541-5549 - issn: 0250-7005 - wos: WOS:000488512600028 (6) - scopus: 2-s2.0-85072761348 (6)

11573/1338788 - 2019 - Structural and functional investigation of the small ribosomal subunit biogenesis GTPase A (RsgA) from pseudomonas aeruginosa
Rocchio, S.; Santorelli, D.; Rinaldo, S.; Franceschini, M.; Malatesta, F.; Imperi, F.; Federici, L.; Travaglini-Allocatelli, C.; Di Matteo, A. - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4245-4260 - issn: 1742-464X - wos: WOS:000493833700007 (7) - scopus: 2-s2.0-85068524955 (8)

11573/1143149 - 2018 - The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells
Giardina, Giorgio; Paone, Alessio; Tramonti, Angela; Lucchi, Roberta; Marani, Marina; Magnifico, Maria Chiara; Bouzidi, Amani; Pontecorvi, Valentino; Guiducci, Giulia; Zamparelli, Carlotta; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3238-3253 - issn: 1742-464X - wos: WOS:000443814200008 (24) - scopus: 2-s2.0-85052452668 (26)

11573/1139413 - 2018 - Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa
Mantoni, Federico; Paiardini, Alessandro; Brunotti, Paolo; D'angelo, Cecilia; Cervoni, Laura; Paone, Alessio; Cappellacci, Loredana; Petrelli, Riccardo; Ricciutelli, Massimo; Leoni, Livia; Rampioni, Giordano; Arcovito, Alessandro; Rinaldo, Serena; Cutruzzolà, Francesca; Giardina, Giorgio - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 3815-3834 - issn: 1742-464X - wos: WOS:000447880900011 (22) - scopus: 2-s2.0-85052825956 (24)

11573/1151881 - 2018 - A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa
Paiardini, A.; Mantoni, F.; Giardina, G.; Paone, A.; Janson, G.; Leoni, L.; Rampioni, G.; Cutruzzolà, F.; Rinaldo, S. - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0887-3585 - wos: WOS:000450353600008 (24) - scopus: 2-s2.0-85052809619 (26)

11573/1113671 - 2018 - Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms
Rinaldo, Serena; Giardina, Giorgio; Mantoni, Federico; Paone, Alessio; Cutruzzolà, Francesca - 01g Articolo di rassegna (Review)
rivista: FEMS MICROBIOLOGY LETTERS ([S.l.] : Blackwell S.l.] : Elsevier Science) pp. fny029- - issn: 1574-6968 - wos: WOS:000441109000002 (43) - scopus: 2-s2.0-85046858121 (44)

11573/1131469 - 2018 - Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes
Tramonti, Angela; Paiardini, Alessandro; Paone, Alessio; Bouzidi, Amani; Giardina, Giorgio; Guiducci, Giulia; Magnifico, Maria Chiara; Rinaldo, Serena; Mcdermott, Lee; Menendez, Javier A.; Contestabile, Roberto; Cutruzzolà, Francesca - 01a Articolo in rivista
rivista: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (Attuale:ELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, USA, NY, 10010-1710 Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 71-79 - issn: 0003-9861 - wos: WOS:000442192500007 (14) - scopus: 2-s2.0-85049429016 (13)

11573/952949 - 2017 - Identification of small molecule inhibitors of the aurora-A/TPX2 complex
Asteriti, Italia Anna; Daidone, F; Colotti, G; Rinaldo, Serena; Lavia, P; Guarguaglini, Giulia; Paiardini, Alessandro - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. - - issn: 1949-2553 - wos: WOS:000401003200118 (19) - scopus: 2-s2.0-85019153604 (20)

11573/954375 - 2017 - Glucose metabolism in the progression of prostate cancer
Cutruzzola', Francesca; Giardina, Giorgio; Marani, Marina; Macone, Alberto; Paiardini, Alessandro; Rinaldo, Serena; Paone, Alessio - 01a Articolo in rivista
rivista: FRONTIERS IN PHYSIOLOGY (Lausanne: Frontiers Research Foundation, 2010-) pp. 97- - issn: 1664-042X - wos: WOS:000394487500001 (90) - scopus: 2-s2.0-85014162527 (99)

11573/1020398 - 2017 - Discovering selective diguanylate cyclase inhibitors: From PleD to discrimination of the active site of cyclic-di-GMP phosphodiesterases
Rinaldo, S.; Giardina, G.; Mantoni, F.; Paiardini, A.; Paone, Alessio; Cutruzzolã , Francesca - 02a Capitolo o Articolo
libro: c-di-GMP signaling - (978-1-4939-7239-5; 978-1-4939-7240-1)

11573/1070158 - 2017 - CHAPTER 4: Nitrite Reductase - Cytochrome cd1
Rinaldo, Serena; Giardina, Giorgio; Cutruzzolà, Francesca - 02a Capitolo o Articolo
libro: RSC Metallobiology - (978-1-78262-334-2)

11573/832010 - 2016 - In silico discovery and in vitro validation of catechol-containing sulfonohydrazide compounds as potent inhibitors of the diguanylate cyclase PleD
Fernicola, Silvia; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Leoni, Livia; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 147-156 - issn: 0021-9193 - wos: WOS:000366587800006 (29) - scopus: 2-s2.0-84953898134 (38)

11573/845279 - 2016 - A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic hydroxymethyltransferase and induces cell death in lung cancer cells
Marani, Marina; Paone, Alessio; Fiascarelli, Alessio; Macone, Alberto; Gargano, Maurizio; Rinaldo, Serena; Giardina, Giorgio; Pontecorvi, Valentino; Koes, David; Mcdermott, Lee; Yang, Tianyi; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca - 01a Articolo in rivista
rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 4570-4583 - issn: 1949-2553 - wos: WOS:000369952400069 (42) - scopus: 2-s2.0-84958012663 (43)

11573/832012 - 2016 - Novel genetic tools to tackle c-di-GMP-dependent signaling in Pseudomonas aeruginosa
Vishnu Pawar, Sarika; Messina, Marco; Rinaldo, Serena; Cutruzzola', Francesca; Kaever, Volkhard; Rampioni, Giordano; Leoni, Livia - 01a Articolo in rivista
rivista: JOURNAL OF APPLIED MICROBIOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 205-217 - issn: 1364-5072 - wos: WOS:000367686900019 (15) - scopus: 2-s2.0-84954525196 (15)

11573/832011 - 2015 - Synthesis of triazole-linked analogues of c-di-gmp and their interactions with diguanylate cyclase
Fernicola, Silvia; Torquati, Ilaria; Paiardini, Alessandro; Giardina, Giorgio; Rampioni, Giordano; Messina, Marco; Leoni, Livia; Del Bello, Fabio; Petrelli, Riccardo; Rinaldo, Serena; Cappellacci, Loredana; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8269-8284 - issn: 0022-2623 - wos: WOS:000363915600025 (29) - scopus: 2-s2.0-84945345287 (35)

11573/780499 - 2015 - How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
Giardina, Giorgio; Brunotti, Paolo; Fiascarelli, Alessio; Cicalini, A; Costa, Mg; Buckle, Am; Di Salvo, Martino Luigi; Giorgi, Alessandra; Marani, Marina; Paone, Alessio; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. - - issn: 1742-464X - wos: WOS:000352226400005 (69) - scopus: 2-s2.0-84964265516 (74)

11573/780502 - 2015 - Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase
Paiardini, Alessandro; Fiascarelli, Alessio; Rinaldo, Serena; Daidone, Frederick; Giardina, Giorgio; Koes, Dr; Parroni, Alessia; Montini, G; Marani, Marina; Paone, Alessio; Mcdermott, La; Contestabile, Roberto; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 490-497 - issn: 1860-7179 - wos: WOS:000350456200006 (28) - scopus: 2-s2.0-84923349870 (29)

11573/781589 - 2015 - Structural basis of functional diversification of the HD-GYP domain revealed by the pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site
Rinaldo, Serena; Paiardini, Alessandro; Stelitano, Valentina; Brunotti, Paolo; Cervoni, Laura; Fernicola, Silvia; Protano, Carmela; Vitali, Matteo; Cutruzzola', Francesca; Giardina, Giorgio - 01a Articolo in rivista
rivista: JOURNAL OF BACTERIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 1525-1535 - issn: 0021-9193 - wos: WOS:000351738600021 (28) - scopus: 2-s2.0-84930786571 (30)

11573/613990 - 2014 - Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR
Cutruzzola', Francesca; Alessandro, Arcovito; Giardina, Giorgio; Stefano Della, Longa; D'angelo, Paola; Rinaldo, Serena - 01a Articolo in rivista
rivista: BIOMETALS (Rapid Science Publishers:2-6 Boundary Row, London SE1 8HN United Kingdom:011 44 207 9407500, EMAIL: rapidcom@vax.oxford.ac.uk, Fax: 011 44 207 8650027) pp. 763-773 - issn: 0966-0844 - wos: WOS:000339878700016 (14) - scopus: 2-s2.0-84905093005 (14)

11573/542045 - 2014 - The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.
Paiardini, Alessandro; P., Aducci; Cervoni, Laura; Cutruzzola', Francesca; C. D., Lucente; Janson, Giacomo; Pascarella, Stefano; Rinaldo, Serena; S., Visconti; L., Camoni - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 52-62 - issn: 1521-6543 - wos: WOS:000331299000008 (24) - scopus: 2-s2.0-84893774983 (24)

11573/618583 - 2014 - SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
Paone, Alessio; Marani, Marina; Fiascarelli, Alessio; Rinaldo, Serena; Giardina, Giorgio; Contestabile, Roberto; Paiardini, Alessandro; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: CELL DEATH & DISEASE (Nature Group) pp. e1525- - issn: 2041-4889 - wos: WOS:000345643900019 (87) - scopus: 2-s2.0-84923383679 (88)

11573/613995 - 2014 - Nitrosylation of c heme in cd(1)-nitrite reductase is enhanced during catalysis
Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 449-454 - issn: 0006-291X - wos: WOS:000341553700018 (1) - scopus: 2-s2.0-84908365280 (1)

11573/514722 - 2013 - The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
Davide, Antoniani; Elio, Rossi; Rinaldo, Serena; Paola, Bocci; Marco, Lolicato; Paiardini, Alessandro; Nadia, Raffaelli; Cutruzzola', Francesca; Paolo, Landini - 01a Articolo in rivista
rivista: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (Germany: Springer Verlag Germany:Tiergartenstrasse) pp. 7325-7336 - issn: 0175-7598 - wos: WOS:000322408100024 (59) - scopus: 2-s2.0-84881232457 (68)

11573/534127 - 2013 - Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: Clues from the structure of the catalytic domain
Giardina, Giorgio; Paiardini, Alessandro; Fernicola, Silvia; Stefano, Franceschini; Rinaldo, Serena; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e81324- - issn: 1932-6203 - wos: WOS:000327541700059 (36) - scopus: 2-s2.0-84896718101 (39)

11573/509344 - 2013 - Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy
Stelitano, Valentina; A., Brandt; Fernicola, Silvia; S., Franceschini; Giardina, Giorgio; A., Pica; Rinaldo, Serena; F., Sica; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: NUCLEIC ACIDS RESEARCH (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485 Editore precedente: Information Retrieval ltd., London) pp. e79-e79 - issn: 0305-1048 - wos: WOS:000318167900006 (33) - scopus: 2-s2.0-84876543297 (38)

11573/525774 - 2013 - C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG
Stelitano, Valentina; Giardina, Giorgio; Paiardini, Alessandro; Castiglione, Nicoletta; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e74920- - issn: 1932-6203 - wos: WOS:000324494000139 (46) - scopus: 2-s2.0-84884194723 (50)

11573/435909 - 2012 - Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease
Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 684-716 - issn: 1523-0864 - wos: WOS:000305470500010 (52) - scopus: 2-s2.0-84862566342 (55)

11573/488091 - 2012 - Interactions outside the Boundaries of the Canonical Binding Groove of a PDZ Domain Influence Ligand Binding
Celestine N., Chi; S., Raza Haq; Rinaldo, Serena; Jakob, Dogan; Cutruzzola', Francesca; Åke, Engstrom; Gianni, Stefano; Patrik, Lundstrom; Per, Jemth - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 8971-8979 - issn: 0006-2960 - wos: WOS:000310664200025 (17) - scopus: 2-s2.0-84868600086 (18)

11573/488094 - 2012 - Solvent Accessibility in the Distal Heme Pocket of the Nitrosyl d1-Heme Complex of Pseudomonas Stutzeri cd1 Nitrite Reductase.
Radoul, M; Barak, Y; Rinaldo, Serena; Cutruzzola', Francesca; Pecht, I; Goldfarb, D. - 01a Articolo in rivista
rivista: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 9192-9201 - issn: 0006-2960 - wos: WOS:000311189900017 (4) - scopus: 2-s2.0-84869209770 (4)

11573/441049 - 2012 - Unusual Heme Binding Properties of the Dissimilative Nitrate Respiration Regulator, a Bacterial Nitric Oxide Sensor
Rinaldo, Serena; Castiglione, Nicoletta; Giardina, Giorgio; Caruso, Manuela; Alessandro, Arcovito; S., Della Longa; D'angelo, Paola; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: ANTIOXIDANTS & REDOX SIGNALING (Mary Ann Liebert Incorporated:2 Madison Avenue:Larchmont, NY 10538:(914)834-3100, EMAIL: info@liebertpub.com, swilliams@liebertpub.com, INTERNET: http://www.liebertpub.com, Fax: (914)834-3688) pp. 1178-1189 - issn: 1523-0864 - wos: WOS:000308405800002 (21) - scopus: 2-s2.0-84865627725 (23)

11573/375989 - 2011 - Metabolism of cyclic-di-GMP in bacterial biofilms: From a general overview to biotechnological applications
Castiglione, Nicoletta; Stelitano, Valentina; Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: INDIAN JOURNAL OF BIOTECHNOLOGY (New Delhi : National Institute of Science Communication and Information Resources, CSIR) pp. 423-431 - issn: 0972-5849 - wos: WOS:000297905800007 (5) - scopus: 2-s2.0-83455170648 (5)

11573/387166 - 2011 - Structure and function of the DNR transcription factor, a master regulator of nitric oxide homeostasis in Pseudomonas aeruginosa
Cutruzzola', Francesca; Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Caruso, M.; Arcovito, A.; Della Longa, S.; D'angelo, Paola - 04c Atto di convegno in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 166-166 - issn: 1742-4658 - wos: WOS:000292333101293 (0) - scopus: (0)
congresso: 36th FEBS Congress, Biochemistry for Tomorrow's Medicine (Lingotto Conference Center, Torino, Italy)

11573/377566 - 2011 - In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Daidone, Frederick; Florio, Rita; Rinaldo, Serena; Contestabile, Roberto; Di Salvo, Martino Luigi; Cutruzzola', Francesca; Bossa, Francesco; Paiardini, Alessandro - 01a Articolo in rivista
rivista: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1616-1621 - issn: 0223-5234 - wos: WOS:000289655100017 (50) - scopus: 2-s2.0-79953228534 (52)

11573/359031 - 2011 - The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide sensing mechanism.
Giardina, Giorgio; Castiglione, Nicoletta; Caruso, Manuela; Cutruzzola', Francesca; Rinaldo, Serena - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 294-298 - issn: 0300-5127 - wos: WOS:000287438000053 (25) - scopus: 2-s2.0-79551487830 (26)

11573/410597 - 2011 - High field pulse EPR and DFT calculations of nitrosyl d-(1) heme complex of cd(1) nitrite reductase: From resolved ligand nuclear frequencies to structure and function
Goldfarb, D; Radoul, M; Bykov, D.; Sundararajan, M; Neese, F; Rinaldo, Serena; Cutruzzola', Francesca - 04d Abstract in atti di convegno
rivista: ABSTRACTS OF PAPERS - AMERICAN CHEMICAL SOCIETY (Washington, DC: American Chemical Society) pp. 894-INOR- - issn: 0065-7727 - wos: WOS:000291982802615 (0) - scopus: (0)
congresso: 241st National Meeting and Exposition of the American-Chemical-Society (ACS) (Anaheim, CA (USA))

11573/47809 - 2011 - Dynamic hydrogen bonding network in the distal pocket of the nitrosyl complex of Pseudomonas aeruginosa cd1 nitrite reductase
Radoul, M; Bykov, D; Rinaldo, Serena; Cutruzzola', Francesca; Neese, F; Goldfarb, D. - 01a Articolo in rivista
rivista: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ([Washington, USA: American Chemical Society] 1879-) pp. 3043-3055 - issn: 0002-7863 - wos: WOS:000289455200042 (30) - scopus: 2-s2.0-79952262446 (32)

11573/359034 - 2011 - The catalytic mechanism of Pseudomonas aeruginosa cd1 nitrite reductase
Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Stelitano, Valentina; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 195-200 - issn: 0300-5127 - wos: WOS:000287438000034 (19) - scopus: 2-s2.0-79551504905 (20)

11573/227023 - 2011 - Observation of fast release of NO from ferrous d₁ haem allows formulation of a unified reaction mechanism for cytochrome cd₁ nitrite reductases.
Rinaldo, Serena; K. A., Sam; Castiglione, Nicoletta; Stelitano, Valentina; A., Arcovito; Brunori, Maurizio; J. W., Allen; S. J., Ferguson; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL JOURNAL (London : Portland Press) pp. 217-225 - issn: 1470-8728 - wos: WOS:000289182100020 (27) - scopus: 2-s2.0-79952838557 (29)

11573/411203 - 2011 - Characterization of proteins from Pseudomonas aeruginosa involved in c-di-GMP turnover
Stelitano, Valentina; Caruso, Manuela; Castiglione, Nicoletta; Giardina, Giorgio; Rinaldo, Serena; Cutruzzola', Francesca - 04d Abstract in atti di convegno
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 172-173 - issn: 1742-464X - wos: WOS:000292333101314 (0) - scopus: (0)
congresso: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine (Torino, ITALY)

11573/411221 - 2010 - Inhibition Of Bacterial Biofilms: New Molecular Strategies Targeting Cyclic-Di-GMP Metabolism.
Stelitano, Valentina; Rinaldo, Serena; Giardina, Giorgio; Castiglione, Nicoletta; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso
congresso: International Conference on Genomic Sciences 2010(ICGS 2010) (Madurai (India))

11573/411378 - 2009 - Nitrite reduction, a function emerging from a pre-aerobic past
Brunori, Maurizio; Castiglione, Nicoletta; Giardina, Giorgio; I., Pecht; Rinaldo, Serena; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso
congresso: 54mo Congresso Societa' Biochimica e Biologia Molecolare (Catania (I))

11573/411382 - 2009 - THE TRANSCRIPTION FACTOR DNR FROM PSEUDOMONAS AERUGINOSA SPECIFICALLY REQUIRES NITRIC OXIDE AND HEME FOR THE ACTIVATION OF A TARGET PROMOTER IN ESCHERICHIA COLI
Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Caruso, Manuela; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso
congresso: 54mo Convegno Societa' Biochimica e Biologia Molecolare (Catania (I))

11573/359009 - 2009 - The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli
Castiglione, Nicoletta; Rinaldo, Serena; Giardina, Giorgio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: MICROBIOLOGY (Society for General Microbiology:Marlboro House, Basingstoke Road, Spencers Wood, Reading RG7 1AE United Kingdom:011 44 118 9881814, EMAIL: d.smith@sgm.ac.ukadmin@socgenmicrobiol.org.uk, INTERNET: http://www.sgm.ac.uk, Fax: 011 44 118 9885656) pp. 2838-2844 - issn: 1350-0872 - wos: WOS:000270264300004 (47) - scopus: 2-s2.0-69949151824 (45)

11573/358279 - 2009 - Nitrite reduction: a ubiquitous function from a pre-aerobic past
Cutruzzola', Francesca; Rinaldo, Serena; Castiglione, Nicoletta; Giardina, Giorgio; Israel, Pecht; Brunori, Maurizio - 01a Articolo in rivista
rivista: BIOESSAYS (-HOBOKEN, USA, NJ: JOHN WILEY & SONS INC -Cambridge : Cambridge University Press, 1984-) pp. 885-891 - issn: 0265-9247 - wos: WOS:000268762500009 (15) - scopus: 2-s2.0-70349972020 (15)

11573/359024 - 2009 - Intramolecular electron transfer in Pseudomonas aeruginosa cd1 nitrite reductase: thermodynamics and kinetics
Farver, O; Brunori, Maurizio; Cutruzzola', Francesca; Rinaldo, Serena; Wherland, S; Pecht, I. - 01a Articolo in rivista
rivista: BIOPHYSICAL JOURNAL (New York: Published for the Biophysical Society by the Rockefeller University Press) pp. 2849-2856 - issn: 0006-3495 - wos: WOS:000266376900029 (27) - scopus: 2-s2.0-67649337219 (27)

11573/411372 - 2009 - DNR FROM PSEUDOMONAS AERUGINOSA: STRUCTURAL AND SPECTROSCOPIC PROPERTIES OF A BACTERIAL NO-SENSOR
Giardina, Giorgio; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Arcovito, A.; Della Longa, S.; D’Angelo, P.; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso
congresso: 54 Convegno Società Italiana di Biochimica e Biologia Molecolare (Catania)

11573/357837 - 2009 - A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild type DNR
Giardina, Giorgio; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 174-180 - issn: 0887-3585 - wos: WOS:000269300000015 (30) - scopus: 2-s2.0-70349334424 (28)

11573/411240 - 2009 - BIOFILM FORMATION IN THE HUMAN PATHOGEN PSEUDOMONAS AERUGINOSA: A STRUCTURAL BIOLOGY STUDY OF PROTEINS INVOLVED IN c-diGMP HOMEOSTASIS
Giardina, Giorgio; Stelitano, Valentina; Rinaldo, Serena; Castiglione, Nicoletta; Caruso, Manuela; Brunori, Maurizio; Cutruzzola', Francesca - 04a Atto di comunicazione a congresso
congresso: EUROBIOFILMS 2009 (ROMA (I))

11573/366598 - 2009 - Heme d1 Nitrosyl Complex of cd1 Nitrite Reductase Studied by High-Field-Pulse Electron Paramagnetic Resonance Spectroscopy
Radoul, M; Centola, F; Rinaldo, Serena; Cutruzzola', Francesca; Pecht, I; Goldfarb, D. - 01a Articolo in rivista
rivista: INORGANIC CHEMISTRY (Washington, DC: American Chemical Society) pp. 3913-3915 - issn: 0020-1669 - wos: WOS:000265749000006 (13) - scopus: 2-s2.0-66149118133 (12)

11573/44486 - 2009 - XAS study of the active site of a bacterial heme-sensor
S., Della Longa; A., Arcovito; Brunori, Maurizio; Castiglione, Nicoletta; Cutruzzola', Francesca; D'angelo, Paola; Giardina, Giorgio; Rinaldo, Serena - 01a Articolo in rivista
rivista: JOURNAL OF PHYSICS. CONFERENCE SERIES (Bristol : Institute of Physics Publishing) pp. 012202-012202 - issn: 1742-6588 - wos: WOS:000275152100203 (1) - scopus: 2-s2.0-73449111238 (1)

11573/359022 - 2008 - NO-sensing in Pseudomonas aeruginosa: Structure of the transcriptional regulator DNR
Giardina, Giorgio; Rinaldo, Serena; Johnson K., A; Di Matteo, Adele; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: JOURNAL OF MOLECULAR BIOLOGY (-LONDON, ENGLAND: ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, -London; New York: Academic Press.) pp. 1002-1015 - issn: 0022-2836 - wos: WOS:000256171900004 (70) - scopus: 2-s2.0-42649125235 (71)

11573/358998 - 2008 - New insights into the activity of Pseudomonas aeruginosa cd(1) nitrite reductase
Rinaldo, Serena; Arcovito, A; Giardina, Giorgio; Castiglione, Nicoletta; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 1155-1159 - issn: 0300-5127 - wos: WOS:000261749200011 (18) - scopus: 2-s2.0-59149088482 (17)
congresso: Biochemical Society Focused Meeting Transition metals in biochemistry (Norwich; United Kingdom)
libro: Biochemical Society Focused Meeting Transition metals in biochemistry - ()

11573/46564 - 2008 - Ancient hemes for ancient catalysts
Rinaldo, Serena; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: PLANT SIGNALING & BEHAVIOR (landes bioscience Kimberly Mitchell Journals Publications Director 810 S. Church St. Georgetown, TX 78626 ph. 512.863.7762 fax. 512.863.0081 kmitchell@landesbioscience.com) pp. 135-136 - issn: 1559-2316 - wos: WOS:000213928700017 (6) - scopus: 2-s2.0-42249085806 (8)

11573/361907 - 2007 - Reaction of Aplysia limacina metmyoglobin with hydrogen peroxide
Dimitri A., Svistunenko; Brandon J., Reeder; Mieebi M., Wankasi; Radu Lucian Silaghi, Dumitrescu; Chris E., Cooper; Rinaldo, Serena; Cutruzzola', Francesca; Michael T., Wilson - 01a Articolo in rivista
rivista: DALTON TRANSACTIONS (Royal Society of Chemistry:Thomas Graham House, Science Park, Cambridge CB4 0WF United Kingdom:011 44 1223 432360, EMAIL: sales@rsc.org, INTERNET: http://www.rsc.org, http://www.chensoc.org, Fax: 011 44 1223 423429) pp. 840-850 - issn: 1477-9226 - wos: WOS:000244691200006 (31) - scopus: 2-s2.0-33847016052 (34)

11573/359033 - 2007 - Fast dissociation of nitric oxide from ferrous Pseudomonas aeruginosa cd1 nitrite reductase - A novel outlook on the catalytic mechanism
Rinaldo, Serena; Arcovito, A; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 14761-14767 - issn: 0021-9258 - wos: WOS:000246589000011 (43) - scopus: 2-s2.0-34447527889 (44)

11573/359023 - 2007 - Nitrite controls the release of nitric oxide in Pseudomonas aeruginosa cd(1) nitrite reductase
Rinaldo, Serena; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 662-666 - issn: 0006-291X - wos: WOS:000250359400036 (19) - scopus: 2-s2.0-34848832891 (19)

11573/360614 - 2007 - Nitrite reductases in denitrification
Rinaldo, Serena; Cutruzzola', Francesca - 02a Capitolo o Articolo
libro: BIOLOGY OF THE NITROGEN CYCLE - (0444528571)

11573/359028 - 2006 - Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1 nitrite reductase with oxygen
Centola, F; Rinaldo, Serena; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: THE FEBS JOURNAL (Blackwell Pub., Oxford, UK) pp. 4495-4503 - issn: 1742-464X - wos: WOS:000240558500013 (5) - scopus: 2-s2.0-33748750224 (5)

11573/410682 - 2006 - PSEUDOMONAS AERUGINOSA NITRITE REDUCTASE: CATALYTIC AND REGULATORY MECHANISMS
Cutruzzola', Francesca; Rinaldo, Serena; Fabio, Centola; Brunori, Maurizio - 04a Atto di comunicazione a congresso
rivista: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES (Soc Porphyrins & Phthalocyanin:6 Boulevard Gabriel, JPP Office, 21000 Dijon France:011 33 3 80396118, EMAIL: jpp@u-bourgogne.fr, Fax: 011 33 3 80396869) pp. - - issn: 1088-4246 - wos: (0) - scopus: (0)
congresso: International Conference on Porphyrins and Phtalocyanins (ICPP4) (ROMA)

11573/361552 - 2006 - N-oxide sensing and denitrification: the DNR transcription factors
Rinaldo, Serena; Giardina, Giorgio; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 185-187 - issn: 0300-5127 - wos: WOS:000235265500048 (13) - scopus: 2-s2.0-32544450194 (14)
congresso: 11th Nitrogen Cycle Meeting (Granada, SPAIN)

11573/359020 - 2005 - N-oxide sensing in Pseudomonas aeruginosa: expression and preliminary characterization of DNR, an FNR-CRP type transcriptional regulator.
Rinaldo, Serena; Giardina, Giorgio; Brunori, Maurizio; Cutruzzola', Francesca - 01a Articolo in rivista
rivista: BIOCHEMICAL SOCIETY TRANSACTIONS (Portland Press Limited:Commerce Way, Colchester CO2 8HP Essex United Kingdom:011 44 1206 796351, EMAIL: sales@portland-services.com, INTERNET: http://www.portland-services.com, Fax: 011 44 1206 799331) pp. 184-186 - issn: 0300-5127 - wos: WOS:000227269800054 (7) - scopus: 2-s2.0-14644401763 (7)

11573/393040 - 2003 - NO production by Pseudomonas aeruginosa cd1 nitrite reductase.
Cutruzzola', Francesca; Rinaldo, Serena; Centola, F; Brunori, Maurizio - 01a Articolo in rivista
rivista: IUBMB LIFE (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 617-621 - issn: 1521-6543 - wos: WOS:000187526800011 (18) - scopus: 2-s2.0-0346991917 (20)

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