SAULA CHECQUOLO

Associate professor

email: saula.checquolo@uniroma1.it
phone: 0649255674

PRESENT POSITION
Associate Professor, General Pathology, MED/04

DEPARTMENT OF MEDICO-SURGICAL SCIENCES AND BIOTECHONOLOGIES

EDUCATION AND CAREER
2008 - present: Assistant Professor, General Pathology (SSD MED/04), Dept. of Medico-Surgical Sciences and Siotechonologies, University La Sapienza.
2006 - 2008: Research Associate (Post-doc) - Fellowship of Italian Federation of Cancer Research (FIRC) - Dept. Experimental Medicine, University La Sapienza.
2005 - 2006: Research Associate (Post-doc) - Fellowship of Italian Association of Cancer Research (AIRC) - Dept. Experimental Medicine, University La Sapienza.
2001 - 2004: PhD in Immunological Sciences, Dept of Experimental Medicine, University La Sapienza.
2000: Degree in Biological Sciences, University La Sapienza. Graduation Cum Laude.

MOST RELEVANT RESEARCH LINES
1. Analysis of cellular and molecular mechanisms involved in female solid tumors (breast and ovarian cancers): role of Notch signaling and its implications in molecular mechanisms of drug resistance.
2. Analysis of Notch receptors role in cancer, through both in vitro and in vivo studies:
i) identification of Notch post-transductional modifications (PTMs) events regulating its expression/function in cancers, ii) identification of Notch cross-talk with other signaling pathways in regulating cancer behaviour; iii) identification of therapeutic application of Notch targeting as novel approach in the treatment of Notch-driving cancers.
3. Analysis of cellular and molecular mechanisms involved in T cell leukemia development and progression and identification of new molecular markers of TALLs.

FIVE SELECTED PUBLICATIONS
1. Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.
Maria Valeria Giuli, Giulia Diluvio, Eugenia Giuliani, Giulia Franciosa, Laura Di Magno, Maria Gemma Pignataro, Luca Tottone, Carmine Nicoletti, Zein Mersini Besharat, Giovanna Peruzzi, Maria Pelullo, Rocco Palermo, Gianluca Canettieri, Claudio Talora, Giulia d’Amati, Diana Bellavia, Isabella Screpanti and Saula Checquolo. Oncogenesis. 2020. Oct 18;9(10):93. DOI: 10.1038/s41389-020-00279-7. PMID: 33071287.
2. Notch Signaling Activation as a Hallmark for Triple-Negative Breast Cancer Subtype. Giuli MV, Giuliani E, Screpanti I, Bellavia D, Checquolo S. J Oncol. 2019. Jul 11;2019:8707053. DOI: 10.1155/2019/8707053. eCollection 2019. PMID: 31379945.
3. Kras/ADAM17-dependent Jag1-ICD reverse signaling sustains colorectal cancer progression and chemoresistance. Pelullo M, Nardozza F, Zema S, Quaranta R, Nicoletti C, Besharat ZM, Felli MP, Cerbelli B, d'Amati, G, Palermo R, Capalbo C, Talora C, Marcotullio LD, Giannini G, Checquolo S*, Screpanti I, Bellavia D*. Cancer Research. 2019. Nov 1;79(21):5575-5586. DOI: 10.1158/0008-5472.CAN-19-0145. Epub 2019 Sep 10. PMID: 31506332. * co-corresponding authors
4. NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest. G. Diluvio, F. Del Gaudio, M. V. Giuli, G. Franciosa, E. Giuliani, R. Palermo, Z. M. Besharat, M. G. Pignataro, A. Vacca, G. d'Amati, M. Maroder, C. Talora, C. Capalbo, D. Bellavia, S. Checquolo..Oncogenesis. 2018. May 25;7(5):42. DOI: 10.1038/s41389-018-0051-9. PMID: 29795369.
5. Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. G. Franciosa, G. Diluvio, F. D. Gaudio, M. V. Giuli, R. Palermo, P. Grazioli, A. F. Campese, C. Talora, D. Bellavia, G. D'Amati, Z. M. Besharat, C. Nicoletti, C. W. Siebel, L. Choy, A. Rustighi, G. D. Sal, I. Screpanti, S. Checquolo.Oncogene. 2016. Sep 8;35(36):4741-51.DOI: 10.1038/onc.2016.5. PMID: 26876201.

Research products

11573/1718047 - 2024 - Dilated cardiomyopathy due to a novel combination of TTN and BAG3 genetic variants: From acute heart failure to subclinical phenotypes

Bottillo, Irene; Giordano, Carla; Ciccone, Maria Pia; Pignataro, Maria Gemma; Albi, Fiammetta; Parisi, Gabriella; Formicola, Daniela; Grotta, Simona; Ranocchi, Federico; Giuli, Maria Valeria; Checquolo, Saula; Masuelli, Laura; Lo Re, Federica; Majore, Silvia; D'amati, Giulia; Grammatico, Paola - 01i Case report

paper: CARDIOVASCULAR PATHOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. - - issn: 1054-8807 - wos: WOS:001293480100001 (1) - scopus: 2-s2.0-85200815242 (1)

11573/1693986 - 2024 - pH-sensitive niosomes for ATRA delivery. A promising approach to inhibit Pin1 in high-grade serous ovarian cancer

Giuli, Maria Valeria; Hanieh, Patrizia Nadia; Forte, Jacopo; Fabiano, Maria Gioia; Mancusi, Angelica; Natiello, Bianca; Rinaldi, Federica; Del Favero, Elena; Grazia Ammendolia, Maria; Marianecci, Carlotta; Checquolo, Saula; Carafa, Maria - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF PHARMACEUTICS (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. - - issn: 0378-5173 - wos: WOS:001133086100001 (1) - scopus: (0)

11573/1723855 - 2024 - Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery

Renzi, Serena; Digiacomo, Luca; Pozzi, Daniela; Quagliarini, Erica; Vulpis, Elisabetta; Giuli, Maria Valeria; Mancusi, Angelica; Natiello, Bianca; Pignataro, Maria Gemma; Canettieri, Gianluca; Di Magno, Laura; Pesce, Luca; De Lorenzi, Valentina; Ghignoli, Samuele; Loconte, Luisa; Montone, Carmela Maria; Laura Capriotti, Anna; Laganà, Aldo; Nicoletti, Carmine; Amenitsch, Heinz; Rossi, Marco; Mura, Francesco; Parisi, Giacomo; Cardarelli, Francesco; Zingoni, Alessandra; Checquolo, Saula; Caracciolo, Giulio - 01a Articolo in rivista

paper: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 1-20 - issn: 2041-1723 - wos: (0) - scopus: (0)

11573/1659953 - 2023 - Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential

Cardinale, Vincenzo; Carpino, Guido; Overi, Diletta; Safarikia, Samira; Zhang, Wencheng; Kanke, Matt; Franchitto, Antonio; Costantini, Daniele; Riccioni, Olga; Nevi, Lorenzo; Chiappetta, Michele; Onori, Paolo; Franchitto, Matteo; Bini, Simone; Hung, Yu-Han; Lai, Quirino; Zizzari, Ilaria; Nuti, Marianna; Nicoletti, Carmine; Checquolo, Saula; Di Magno, Laura; Giuli, Maria Valeria; Rossi, Massimo; Sethupathy, Praveen; Reid, Lola M; Alvaro, Domenico; Gaudio, Eugenio - 01a Articolo in rivista

paper: JOURNAL OF HEPATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 165-179 - issn: 0168-8278 - wos: WOS:000927845200015 (7) - scopus: 2-s2.0-85138931448 (8)

11573/1676923 - 2023 - Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease

Zonfrilli, A.; Truglio, F.; Simeone, A.; Pelullo, M.; Deturris, V.; Benelli, D.; Checquolo, S.; Bellavia, D.; Palermo, R.; Uccelletti, D.; Screpanti, I.; Cialfi, S.; Talora, C. - 01a Articolo in rivista

paper: EXPERIMENTAL DERMATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1-12 - issn: 0906-6705 - wos: WOS:000938040500001 (0) - scopus: 2-s2.0-85149748147 (2)

11573/1615334 - 2022 - Opsonin-deficient nucleoproteic corona endows unPEGylated liposomes with stealth properties in vivo

Giulimondi, F.; Vulpis, E.; Digiacomo, L.; Giuli, M. V.; Mancusi, A.; Capriotti, A. L.; Lagana, A.; Cerrato, A.; Zenezini Chiozzi, R.; Nicoletti, C.; Amenitsch, H.; Cardarelli, F.; Masuelli, L.; Bei, R.; Screpanti, I.; Pozzi, D.; Zingoni, A.; Checquolo, S.; Caracciolo, G. - 01a Articolo in rivista

paper: ACS NANO (Washington, DC : American Chemical Society) pp. 2088-2100 - issn: 1936-0851 - wos: WOS:000746639100001 (33) - scopus: 2-s2.0-85123925991 (39)

11573/1659734 - 2022 - 5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer. A novel mechanism of intrinsic drug resistance

Pelullo, Maria; Zema, Sabrina; De Carolis, Mariangela; Cialfi, Samantha; Giuli, Maria Valeria; Palermo, Rocco; Capalbo, Carlo; Giannini, Giuseppe; Screpanti, Isabella; Checquolo, Saula; Bellavia, Diana - 01a Articolo in rivista

paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 1-10 - issn: 2234-943X - wos: WOS:000827974000001 (3) - scopus: 2-s2.0-85134211105 (3)

11573/1664088 - 2022 - Identification of a novel curcumin derivative influencing notch pathway and DNA damage as a potential therapeutic agent in T-ALL

Zhdanovskaya, Nadezda; Lazzari, Sara; Caprioglio, Diego; Firrincieli, Mariarosaria; Maioli, Chiara; Pace, Eleonora; Imperio, Daniela; Talora, Claudio; Bellavia, Diana; Checquolo, Saula; Mori, Mattia; Screpanti, Isabella; Minassi, Alberto; Palermo, Rocco - 01a Articolo in rivista

paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000897324700001 (4) - scopus: 2-s2.0-85143627645 (4)

11573/1612769 - 2021 - Notch signaling in female cancers. A multifaceted node to overcome drug resistance

Giuli, M. V.; Mancusi, A.; Giuliani, E.; Screpanti, I.; Checquolo, S. - 01g Articolo di rassegna (Review)

paper: CANCER DRUG RESISTANCE (Alhambra CA: OAE Publishing Inc., 2018-) pp. 805-836 - issn: 2578-532X - wos: WOS:000849619900006 (8) - scopus: 2-s2.0-85117929405 (8)

11573/1502467 - 2020 - Current trends in ATRA delivery for cancer therapy

Giuli, M. V.; Hanieh, P. N.; Giuliani, E.; Rinaldi, F.; Marianecci, C.; Screpanti, I.; Checquolo, S.; Carafa, M. - 01g Articolo di rassegna (Review)

paper: PHARMACEUTICS (Basel: MDPI, 2009-) pp. 1-32 - issn: 1999-4923 - wos: WOS:000564057100001 (45) - scopus: 2-s2.0-85088942324 (46)

11573/1446421 - 2020 - Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

Giuli, Maria Valeria; Diluvio, Giulia; Giuliani, Eugenia; Franciosa, Giulia; Di Magno, Laura; Pignataro, Maria Gemma; Tottone, Luca; Nicoletti, Carmine; Besharat, Zein Mersini; Peruzzi, Giovanna; Pelullo, Maria; Palermo, Rocco; Canettieri, Gianluca; Talora, Claudio; D'amati, Giulia; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 01a Articolo in rivista

paper: ONCOGENESIS (London Nature Publishing Group) pp. 1-16 - issn: 2157-9024 - wos: WOS:000579242100001 (15) - scopus: 2-s2.0-85092794807 (14)

11573/1210601 - 2019 - Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation

Antonucci, Laura; Di Magno, Laura; D'amico, Davide; Manni, Simona; Serrao, Silvia Maria; Di Pastena, Fiorella; Bordone, Rosa; Yurtsever, Zuleyha Nihan; Caimano, Miriam; Petroni, Marialaura; Giorgi, Alessandra; Schininà, Maria Eugenia; Yates Iii, John R; Di Marcotullio, Lucia; De Smaele, Enrico; Checquolo, Saula; Capalbo, Carlo; Agostinelli, Enzo; Maroder, Marella; Coni, Sonia; Canettieri, Gianluca - 01a Articolo in rivista

paper: INTERNATIONAL JOURNAL OF ONCOLOGY (National Hellenic Research Foundation:48 Vas Constatinou Avenue, Athens 11635 Greece:011 30 1 7241505, Fax: 011 30 1 7241505Editore attuale:PROFESSOR D A SPANDIDOS, 1, S MERKOURI ST, EDITORIAL OFFICE,, ATHENS, GREECE, 116 35. Editore precedente:Editorial Academy of the International Journal of Oncology.) pp. 505-514 - issn: 1019-6439 - wos: WOS:000454923900009 (25) - scopus: 2-s2.0-85058877986 (27)

11573/1225914 - 2019 - Notch3 targeting. A novel weapon against ovarian cancer stem cells

Ceccarelli, Simona; Megiorni, Francesca; Bellavia, Diana; Marchese, Cinzia; Screpanti, Isabella; Checquolo, Saula - 01g Articolo di rassegna (Review)

paper: STEM CELLS INTERNATIONAL (Cairo: Hindawi Publishing Corporation) pp. 1-8 - issn: 1687-966X - wos: WOS:000456842000001 (22) - scopus: 2-s2.0-85061392458 (24)

11573/1345708 - 2019 - PLK1 targets NOTCH1 during DNA damage and mitotic progression

De Blasio, Carlo; Zonfrilli, A.; Franchitto, Matteo; Mariano, G.; Cialfi, S.; Verma, Nagendra; Checquolo, S.; Bellavia, D.; Palermo, R.; Benelli, D.; Screpanti, I.; Talora, C. - 01a Articolo in rivista

paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 17941-17950 - issn: 0021-9258 - wos: WOS:000504206800020 (15) - scopus: 2-s2.0-85075566790 (16)

11573/1303782 - 2019 - Notch signaling activation as a hallmark for triple-negative breast cancer subtype

Giuli, M. V.; Giuliani, E.; Screpanti, I.; Bellavia, D.; Checquolo, S. - 01g Articolo di rassegna (Review)

paper: JOURNAL OF ONCOLOGY (Cairo: Hindawi Publishing Corporation) pp. - - issn: 1687-8450 - wos: WOS:000476770500001 (112) - scopus: 2-s2.0-85069758376 (115)

11573/1344899 - 2019 - Molecular basis of Notch3-Pin1 functional crosstalk in aggressive female tumors: therapeutic targeting implications in ovarian cancer treatment

Giuli, Mv; Giuliani, E; Mancusi, A; Franciosa, G; Olsen, Jv; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: SIPMeT Young Meeting (Firenze, Italy)

book: PATHOBIOLOGY: FROM MOLECULAR DISEASE TO CLINICAL APPLICATION - ()

11573/1344900 - 2019 - Notch3-Pin1 crosstalk in ovarian cancer: from molecular mechanism dissection to therapeutic application

Giuli, Mv; Giuliani, E; Mancusi, A; Franciosa, G; Olsen, Jv; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: The XI Notch meeting (Athens, Greece)

book: The XI Notch meeting - ()

11573/1344902 - 2019 - Getting insights into Pin1-Notch3 functional crosstalk in ovarian cancer

Giuli, Mv; Giuliani, E; Mancusi, A; Franciosa, G; Olsen, Jv; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: 4Th ANNUAL MEETING OF ALLIANCE AGAINST CANCER (ACC) (Roma, Italy)

book: NEW TECHNOLOGIES TO FIGHT CANCER - ()

11573/1347680 - 2019 - Notch3 contributes to T-cell leukemia growth via regulation of the unfolding protein response

Giuliani, Eugenia; Giuli, Maria Valeria; Diluvio, Giulia; Pelullo, Maria; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 04d Abstract in atti di convegno

conference: The Biennial Congress of the Italian Association of cell biology and differentiation (Bologna, Italy)

book: The Biennial Congress of the Italian Association of cell biology and differentiation - ()

11573/1310873 - 2019 - Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance

Pelullo, Maria; Nardozza, Francesca; Zema, Sabrina; Quaranta, Roberta; Nicoletti, Carmine; Besharat, Zein Mersini; Felli, Maria Pia; Cerbelli, Bruna; D’Amati, Giulia; Palermo, Rocco; Capalbo, Carlo; Talora, Claudio; Di Marcotullio, Lucia; Giannini, Giuseppe; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

paper: CANCER RESEARCH (Philadelphia : American Association for Cancer Research) pp. 5575-5586 - issn: 1538-7445 - wos: WOS:000494363200013 (25) - scopus: 2-s2.0-85074445960 (27)

11573/1309854 - 2019 - Wnt, notch, and TGF-β pathways impinge on hedgehog signaling complexity: an open window on cancer

Pelullo, Maria; Zema, Sabrina; Nardozza, Francesca; Checquolo, Saula; Screpanti, Isabella; Bellavia, Diana - 01g Articolo di rassegna (Review)

paper: FRONTIERS IN GENETICS (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-8021 - wos: WOS:000482067800001 (83) - scopus: 2-s2.0-85071472276 (91)

11573/1261501 - 2019 - Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL

Tottone, Luca; Zhdanovskaya, Nadezda; Carmona Pestaña, Álvaro; Zampieri, Michele; Simeoni, Fabrizio; Lazzari, Sara; Ruocco, Valeria; Pelullo, Maria; Caiafa, Paola; Felli, Maria Pia; Checquolo, Saula; Bellavia, Diana; Talora, Claudio; Screpanti, Isabella; Palermo, Rocco - 01a Articolo in rivista

paper: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 1-15 - issn: 2234-943X - wos: WOS:000463425600001 (29) - scopus: 2-s2.0-85067443438 (28)

11573/1130744 - 2018 - The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms

Bellavia, Diana; Checquolo, Saula; Palermo, Rocco; Screpanti, Isabella - 02a Capitolo o Articolo

book: Molecular Mechanisms of Notch Signaling - (978-3-319-89511-6; 978-3-319-89512-3)

11573/1088655 - 2018 - Notch signaling as a therapeutic target for acute lymphoblastic leukemia

Bellavia, Diana; Palermo, Rocco; Felli, Maria Pia; Screpanti, Isabella; Checquolo, Saula - 01g Articolo di rassegna (Review)

paper: EXPERT OPINION ON THERAPEUTIC TARGETS (--London United Kingdom:Informa Healthcare -London : Ashley, 2002-.) pp. 331-342 - issn: 1472-8222 - wos: WOS:000430074900004 (33) - scopus: 2-s2.0-85045679979 (37)

11573/1111436 - 2018 - NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest

Diluvio, Giulia; Del Gaudio, Francesca; Giuli, Maria Valeria; Franciosa, Giulia; Giuliani, Eugenia; Palermo, Rocco; Besharat, Zein Mersini; Pignataro, Maria Gemma; Vacca, Alessandra; D'amati, Giulia; Maroder, Marella; Talora, Claudio; Capalbo, Carlo; Bellavia, Diana; Checquolo, Saula - 01a Articolo in rivista

paper: ONCOGENESIS (London Nature Publishing Group) pp. - - issn: 2157-9024 - wos: WOS:000433997800002 (39) - scopus: 2-s2.0-85047628678 (40)

11573/1114780 - 2018 - Targeting the ER/UPR signalling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.

Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: ABCD - Ph.D. meeting (Salerno)

book: Atti del ABCD - Ph.D. meeting - ()

11573/1344887 - 2018 - Potential targeted therapy for T-cell acute lymphoblastic leukemia: perturbing ER/UPR signaling via Notch3 down-regulation

Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: 31st Annual conference of Italian Association of Cell Cultures (AICC) (Bologna, Italy)

book: Cell communication and signaling: how to turn bad language into positive one - ()

11573/1174598 - 2018 - NOTCH3 inactivation increases Triple Negative Breast Cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.

Giuliani, Eugenia; Giuli, Maria Valeria; Diluvio, Giulia; Del Gaudio, Francesca; Franciosa, Giulia; Bellavia, Diana; Screpanti, Isabella; Checquolo, Saula - 04d Abstract in atti di convegno

conference: ABCD - Ph.D. meeting (Salerno)

book: Atti del ABCD - PPh.D. meeting - ()

11573/1166892 - 2018 - "Notch3 and CXCR4 cross-signaling sustains acute T-cell leukemia progression"

Tsaouli, G; Ferrandino, F; Bernardini, G; Grazioli, P; Campese, Af; Bellavia, D; Checquolo, S; Screpanti, I; Felli., Mp - 01h Abstract in rivista

paper: ESMO OPEN (London: BMJ) pp. A383- - issn: 2059-7029 - wos: (0) - scopus: (0)

11573/1022327 - 2017 - Cytotoxic activity of Juglone against Notch3-overexpressing T-cell acute lymphoblastic leukemia: targeting the ER/UPR signaling

Giuli, Mv; Diluvio, G.; Giuliani, Eugenia; Bellavia, D.; Palermo, R.; Screpanti, I.; Checquolo, S. - 04d Abstract in atti di convegno

book: Notch meeting X - ()

11573/1114777 - 2017 - Role of Notch3 in sustaining UPR signaling in Notch3-overexpressing T-cell acute lymphoblastic leukemia.

Giuli, Mv; Diluvio, G; Giuliani, E; Bellavia, D; Palermo, R; Screpanti, I; Checquolo, S - 04d Abstract in atti di convegno

conference: SIPMeT "Young Scientist Meeting" (Milano)

book: Atti del SIPMeT "Young Scientist Meeting" - ()

11573/969457 - 2017 - Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway

Quaranta, Roberta; Pelullo, Maria; Zema, Sabrina; Nardozza, Francesca; Checquolo, Saula; Lauer, Dieter Matthias; Bufalieri, Francesca; Palermo, Rocco; Felli, Maria Pia; Vacca, Alessandra; Talora, Claudio; Di Marcotullio, Lucia; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. - - issn: 2041-4889 - wos: WOS:000406870400031 (33) - scopus: 2-s2.0-85035040836 (34)

11573/982167 - 2016 - Notch3 sustains CXCR4 expression in acute T cell lymphoblastic leukemia progression

Ferrandino, Francesca; Bernardini, Giovanni; Grazioli, Paola; Campese, Antonio Francesco; Bellavia, Diana; Checquolo, Saula; Screpanti, Isabella; Felli, Maria Pia - 04c Atto di convegno in rivista

paper: EUROPEAN JOURNAL OF CANCER (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. S87-S87 - issn: 0959-8049 - wos: WOS:000431649800307 (0) - scopus: (0)

conference: 24th Biennial Congress of the European Association for Proceedings Book Cancer Research (Manchester, UK)

11573/846078 - 2016 - Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression

Franciosa, Giulia; Diluvio, Giulia; Del Gaudio, Francesca; Giuli, Maria Valeria; Palermo, Rocco; Grazioli, Paola; Campese, Antonio Francesco; Talora, Claudio; Bellavia, Diana; D'amati, Giulia; Besharat, Zein Mersini; Nicoletti, Carmine; Siebel, Christian William; Choy, Lisa; Rustighi, Alessandra; Del Sal, Giannino; Screpanti, Isabella; Checquolo, Saula - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 4741-4751 - issn: 0950-9232 - wos: WOS:000383324700007 (47) - scopus: 2-s2.0-84958093172 (48)

11573/887319 - 2016 - RET mutation and increased angiogenesis in medullary thyroid carcinomas

Verrienti, Antonella; Tallini, Giovanni; Colato, Chiara; Boichard, Amélie; Checquolo, Saula; Pecce, Valeria; Sponziello, Marialuisa; Rosignolo, Francesca; De Biase, Dario; Rhoden, Kerry; Casadei, Gian Piero; Russo, Diego; Visani, Michela; Acquaviva, Giorgia; Ferdeghini, Marco; Filetti, Sebastiano; Durante, Cosimo - 01a Articolo in rivista

paper: ENDOCRINE-RELATED CANCER (Bristol: BioScientifica Bristol: Journal of Endocrinology Ltd, 1994- Journal of Endocrinology Limited:17 18 Courtyard Woodlands, Bristol BS12 4NQ United Kingdom:011 44 117 9616046, EMAIL: sxa15@psu.edu, INTERNET: http://www.psu.edu, Fax: 011 44 117 9616071) pp. 665-676 - issn: 1351-0088 - wos: WOS:000384188900010 (22) - scopus: 2-s2.0-84989306653 (26)

11573/782968 - 2015 - The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPalpha

Vargas Romero, Paula Estefania; Cialfi, Samantha; Palermo, Rocco; De Blasio, Carlo; Checquolo, Saula; Bellavia, Diana; Chiaretti, Sabina; Foa, Roberto; Amadori, Alberto; Gulino, Alberto; Zardo, Giuseppe; Talora, Claudio; Screpanti, Isabella - 01f Lettera, Nota

paper: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 2442-2445 - issn: 0887-6924 - wos: WOS:000366393900032 (29) - scopus: 2-s2.0-84951569042 (28)

11573/670477 - 2014 - Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis

Cialfi, Samantha; Palermo, Rocco; Manca, Sonia; De Blasio, Carlo; Vargas Romero, Paula Estefania; Checquolo, Saula; Bellavia, Diana; Uccelletti, Daniela; Saliola, Michele; Angelo, D’Alessandro; Lello, Zolla; Gulino, Alberto; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2046-2055 - issn: 1538-4101 - wos: WOS:000338041700011 (28) - scopus: 2-s2.0-84903756189 (30)

11573/557636 - 2014 - Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia

Kumar, Vivek; Palermo, Rocco; Talora, Claudio; Campese, Antonio Francesco; Checquolo, Saula; Bellavia, Diana; Tottone, Luca; Testa, G.; Miele, Evelina; Indraccolo, S.; Amadori, A.; Ferretti, Elisabetta; Gulino, Alberto; Vacca, Alessandra; Screpanti, Isabella - 01a Articolo in rivista

paper: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 2324-2335 - issn: 0887-6924 - wos: WOS:000346177500009 (142) - scopus: 2-s2.0-84925282873 (151)

11573/649693 - 2014 - Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.

Martin Blanco, Nm; Checquolo, Saula; Del Gaudio, Francesca; Palermo, Rocco; Franciosa, Giulia; Di Marcotullio, Lucia; Gulino, Alberto; Canelles, M; Screpanti, Isabella - 01a Articolo in rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. Article Number: e1472- - issn: 2041-4889 - wos: WOS:000344994000044 (5) - scopus: 2-s2.0-84925810051 (5)

11573/543225 - 2014 - The Molecular Basis of Notch Signaling Regulation: A Complex Simplicity

Palermo, Rocco; Checquolo, Saula; Bellavia, Diana; Talora, Claudio; Screpanti, Isabella - 01a Articolo in rivista

paper: CURRENT MOLECULAR MEDICINE (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 34-44 - issn: 1566-5240 - wos: WOS:000329187800004 (33) - scopus: 2-s2.0-84891837770 (34)

11573/656612 - 2014 - Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL.

Pelullo, Maria; Quaranta, Roberta; Talora, Claudio; Checquolo, Saula; Cialfi, Samantha; Felli, Maria Pia; Te Kronnie, G; Borga, C; Besharat, Zein Mersini; Palermo, Rocco; Di Marcotullio, Lucia; Capobianco, Aj; Gulino, Alberto; Screpanti, Isabella; Bellavia, Diana - 01a Articolo in rivista

paper: NEOPLASIA (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1007-1017 - issn: 1522-8002 - wos: WOS:000347172100002 (45) - scopus: 2-s2.0-85003322506 (46)

11573/759618 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation process by influencing membrane migration of its transmembrane form

Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, R.; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

conference: ESF-EMBO RESEARCH CONFERENCE (POLONIA)

book: ESF-EMBO RESEARCH CONFERENCE - ()

11573/759623 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation by influencing its migration to the cell membrane

Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

conference: SIPMET 2013 (Roma)

book: SIPMET 2013 - ()

11573/759629 - 2013 - The prolyl-isomerase Pin1 regulates Notch3 receptor maturation process by influencing membrane migration of its transmembrane form

Checquolo, Saula; Franciosa, Giulia; Del Gaudio, Francesca; Diluvio, Giulia; Palermo, Rocco; Talora, Claudio; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

conference: ABCD 2013 (Ravenna)

book: ABCD 2013 - ()

11573/484435 - 2013 - Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression

Cialfi, Samantha; Palermo, Rocco; Sonia, Manca; Checquolo, Saula; Bellavia, Diana; Pelullo, Maria; Quaranta, Roberta; Dominici, Carlo; Gulino, Alberto; Screpanti, Isabella; Talora, Claudio - 01a Articolo in rivista

paper: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 485-488 - issn: 0887-6924 - wos: WOS:000315553600027 (30) - scopus: 2-s2.0-84873566711 (30)

11573/434259 - 2012 - Acetylation controls Notch3 stability and function in T-cell leukemia

Palermo, Rocco; Checquolo, Saula; A., Giovenco; Grazioli, Paola; Kumar, Vivek; Campese, Antonio Francesco; Giorgi, Alessandra; Napolitano, Maddalena; Canettieri, Gianluca; G., Ferrara; Schinina', Maria Eugenia; Maroder, Marella; Frati, Luigi; Gulino, Alberto; Vacca, Alessandra; Screpanti, Isabella - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3807-3817 - issn: 0950-9232 - wos: WOS:000307924900007 (48) - scopus: 2-s2.0-84865202947 (50)

11573/480447 - 2012 - Loss of CBL E3-ligase activity in B-lineage childhood acute lymphoblastic leukaemia

Simone, Martinelli; Checquolo, Saula; Consoli, Federica; Emilia, Stellacci; Cesare, Rossi; Marianna, Silvano; Franciosa, Giulia; Elisabetta, Flex; Carla, Cossu; A., De Luca; Foa, Roberto; Giovanni, Cazzaniga; Andrea, Biondi; Screpanti, Isabella; Marco, Tartaglia - 01a Articolo in rivista

paper: BRITISH JOURNAL OF HAEMATOLOGY (British Society for Haematology and John Wiley & Sons Ltd Oxford: Blackwell, 1955-) pp. 115-119 - issn: 0007-1048 - wos: WOS:000308871500019 (7) - scopus: 2-s2.0-84866335390 (6)

11573/759613 - 2011 - Deletion of NF-kappaB/p50 influences the outcome of NOTCH3-dependent T cell leukemia

Campese, Antonio Francesco; Grazioli, Paola; C., Mari; Scafetta, Gaia; Noce, Claudia; Verkhovskaia, Sofia; Checquolo, Saula; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

conference: THE NOTCH MEETING V (ATENE)

book: THE NOTCH MEETING V - ()

11573/759615 - 2011 - The Prolyl-Isomerase PIN1 represent a regulator of Notch3 activity

Checquolo, Saula; Palermo, Rocco; Franciosa, Giulia; Pelullo, Maria; Bellavia, Diana; Gulino, Alberto; Screpanti, Isabella - 04d Abstract in atti di convegno

conference: THE NOTCH MEETING V (ATENE)

book: THE NOTCH MEETING V - ()

11573/145820 - 2010 - Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia

Checquolo, Saula; Palermo, Rocco; Cialfi, Samantha; Ferrara, Grazia; C., Oliviero; Talora, Claudio; Bellavia, Diana; A., Giovenco; Grazioli, Paola; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 1463-1474 - issn: 0950-9232 - wos: WOS:000275392400005 (27) - scopus: 2-s2.0-77949425560 (27)

11573/501432 - 2010 - NOTCH3: A MORE PROMINENT PLAYER THAN NOTCH1 IN THE PATHOGENESIS OF T-ALL?

E., Radwan; Ferretti, Elisabetta; Checquolo, Saula; Grazioli, Paola; Talora, Claudio; H., Moussa; Campese, Antonio Francesco; M., El Ansary; S., Hussein; D., Yassin; A., Kamel; Screpanti, Isabella - 04c Atto di convegno in rivista

paper: HAEMATOLOGICA (Fondaz Ferrata Storti:Strada Nuova 134, 27100 Pavia Italy:011 39 0382 531182, EMAIL: office@haematologica.it, Fax: 011 39 0382 27721) pp. 4-5 - issn: 0390-6078 - wos: WOS:000279051300011 (1) - scopus: (0)

conference: 15th Annual Meeting of the European-Hematology-Association (Barcelona, SPAIN)

11573/390881 - 2010 - Heterozygous Germline Mutations in the CBL Tumor-Suppressor Gene Cause a Noonan Syndrome-like Phenotype

Simone, Martinelli; Alessandro De, Luca; Emilia, Stellacci; Cesare, Rossi; Checquolo, Saula; Francesca, Lepri; Caputo, Viviana; Marianna, Silvano; Francesco, Buscherini; Consoli, Federica; Ferrara, Grazia; Maria C., Digilio; Cavaliere, Maria Laura; Johanna M., Van Hagen; Giuseppe, Zampino; Ineke Van Der, Burgt; Giovanni B., Ferrero; Laura, Mazzanti; Screpanti, Isabella; Helger G., Yntema; Willy M., Nillesen; Ravi, Savarirayan; Martin, Zenker; Bruno, Dallapiccola; Bruce D., Gelb; Marco, Tartaglia - 01a Articolo in rivista

paper: AMERICAN JOURNAL OF HUMAN GENETICS (University of Chicago Press:PO Box 37005, Journals Division:Chicago, IL 60637:(877)705-1878, (877)705-1878, (773)753-2247, EMAIL: subscriptions@press.uchicago.edu, INTERNET: http://www.press.uchicago.edu, Fax: (877)705-1879, (773)753-0811) pp. 250-257 - issn: 0002-9297 - wos: WOS:000281107000009 (195) - scopus: 2-s2.0-77955583599 (206)

11573/229251 - 2009 - Notch3 and pT{alpha}/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.

Campese, Antonio Francesco; Grazioli, Paola; Colantoni, S; Anastasi, Emanuela; Mecarozzi, Marco; Checquolo, Saula; De Luca, G; Bellavia, Diana; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: INTERNATIONAL IMMUNOLOGY (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 727-743 - issn: 0953-8178 - wos: WOS:000266499800010 (25) - scopus: 2-s2.0-66249108256 (25)

11573/228912 - 2008 - Notch3: from subtle structural differences to functional diversity

Bellavia, Diana; Checquolo, Saula; Campese, Antonio Francesco; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 5092-5098 - issn: 0950-9232 - wos: WOS:000258914900002 (63) - scopus: 2-s2.0-50849112357 (67)

11573/501328 - 2007 - Notch3 and pre-TCR interaction differentially regulate T cell development and leukemogenesis

Bellavia, Diana; Campese, Antonio Francesco; Talora, Claudio; Checquolo, Saula; Vacca, Alessandra; Felli, Maria Pia; Gulino, Alberto; Screpanti, Isabella - 04c Atto di convegno in rivista

paper: IMMUNOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 33-33 - issn: 0019-2805 - wos: WOS:000244080000127 (0) - scopus: (0)

conference: Annual Congress of the British-Society-of-Immunology (Glasgow, SCOTLAND)

11573/358248 - 2005 - PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia

Felli, Maria Pia; Vacca, Alessandra; Calce, A; Bellavia, Diana; Campese, Antonio Francesco; Grillo, R; Di Giovine, M; Checquolo, Saula; Talora, Claudio; Palermo, Rocco; Di Mario, G; Frati, Luigi; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 992-1000 - issn: 0950-9232 - wos: WOS:000226749200005 (63) - scopus: 2-s2.0-13944266008 (68)

11573/387826 - 2003 - Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes

Anastasi, Emanuela; Campese, Antonio Francesco; Bellavia, Diana; A., Bulotta; A., Balestri; M., Pascucci; Checquolo, Saula; Gradini, Roberto; U., Lendahl; Frati, Luigi; Gulino, Alberto; Di Mario, Umberto; Screpanti, Isabella - 01a Articolo in rivista

paper: JOURNAL OF IMMUNOLOGY (American Association of Immunologists:9650 Rockville Pike:Bethesda, MD 20814:(301)634-7024, EMAIL: staff@dues.faseb.org, INTERNET: http://www.aai.org, Fax: (301)634-7099) pp. 4504-4511 - issn: 0022-1767 - wos: WOS:000186136800005 (108) - scopus: 2-s2.0-10744222828 (112)

11573/250473 - 2003 - Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

Talora, Claudio; Campese, Antonio Francesco; Bellavia, Diana; Pascucci, M.; Checquolo, Saula; Groppioni, M.; Frati, Luigi; Von Boehmer, H.; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 1067-1072 - issn: 1469-221X - wos: WOS:000186342800014 (64) - scopus: 2-s2.0-0348133609 (68)

11573/501403 - 2002 - Notch3 transgenic mice are protected against experimental autoimmune diabetes and display enhanced generation of T regulatory cells

Anastasi, Emanuela; Campese, Antonio Francesco; Bellavia, Diana; Bulotta, A.; Emaldi, F.; Balestri, A.; Checquolo, Saula; Gradini, Roberto; Lendahl, U.; Frati, Luigi; Gulino, Alberto; Di Mario, U.; Screpanti, Isabella - 04c Atto di convegno in rivista

paper: DIABETOLOGIA (Springer Verlag Germany:Tiergartenstrasse 17, D 69121 Heidelberg Germany:011 49 6221 3450, EMAIL: g.braun@springer.de, INTERNET: http://www.springer.de, Fax: 011 49 6221 345229) pp. 38-39 - issn: 0012-186X - wos: WOS:000177813600108 (0) - scopus: (0)

conference: 38th EASD Annual Meeting of the European Association for the Study of Diabetes (Budapest, Ungheria)

11573/250487 - 2002 - Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

Bellavia, Diana; Campese, Antonio Francesco; Checquolo, Saula; Balestri, A.; Biondi, A.; Cazzaniga, G.; Lendahl, U.; Fehling, H. J.; Hayday, A. C.; Frati, Luigi; Von Boehmer, H.; Gulino, Alberto; Screpanti, Isabella - 01a Articolo in rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 3788-3793 - issn: 0027-8424 - wos: WOS:000174511000078 (172) - scopus: 2-s2.0-0037133497 (176)

11573/501782 - 2002 - Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

Screpanti, Isabella; Bellavia, Diana; Campese, Antonio Francesco; Checquolo, Saula; Balestri, A.; Biondi, A.; Cazzaniga, G.; Von Boehmer, H.; Frati, Luigi; Gulino, Alberto - 04c Atto di convegno in rivista

paper: EUROPEAN JOURNAL OF CANCER (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 106-106 - issn: 0959-8049 - wos: WOS:000179895700359 (0) - scopus: (0)

conference: 14th EORTC/NCI/AACR Symposium on Molecular Targets and Cancer Therapeutics (Francoforte, Germania)