ROSSELLA TOZZI

Dottoressa di ricerca

ciclo: XXXV


supervisore: Prof.ssa Stefania Mariani
relatore: Prof. Lucio Gnessi

Titolo della tesi: Role of SIRT1 in the regulation of adipose tissue and metabolism: implications with the ketogenic diet.

Sirtuin1 (SIRT1) has a regulatory role mainly in metabolism and aging, extending health span through effects able to prevent metabolic derangements and degenerative diseases, including aging-related bone loss. Being a histone deacetylase using NAD as a cofactor, its activity increases with caloric restriction or starvation. Overnutrition reduce SIRT1, while transgenic mice for SIRT1 overexpression are protected from fatty liver, type 2 diabetes (T2D), age- induced cancer and osteoporosis. We demonstrated that circulating SIRT1 – as well as the tissue – is inversely correlated with fat amounts and coherently associated with the levels of the two well-known adipokines adiponectin and leptin, being predictive of visceral adipose tissue (VAT), specifically. In addition, circulating SIRT1 proved to be directly correlated with bone mineral density and was the best predictor of trabecular structure, reflecting the negative relationship with sclerostin – an osteoblast inhibitor – observed in murine studies. Ketogenesis is a metabolic process involved in controlling energy homeostasis by a fine epigenetic regulation implemented during fasting or intense exercise. Endogenous or exogenous ketosis delay aging by improving anti-inflammatory and mitochondrial activities, mnemonic and muscle performance and reduces metabolic diseases through the disposal of fatty acids. Being proposed as an alternative therapy option even during acute illness such as COVID-19, the ketogenic diet (KD) has been successfully introduced for the treatment of obesity and its main complications such as NAFLD and T2D. Recent advances in understanding the influence on health span and the shared outcomes between ketone bodies and SIRT1 suggest a joint work with the same beneficial intent, probably also via epigenetic modulation. The aim of our study was to understand whether a KD leads to the increase of SIRT1, assuming the role of SIRT1 as a downstream effector of the metabolic adaptations observed during ketosis, beyond caloric restriction and weight loss. We evaluated 20 C57BL/6J 8 weeks old male mice treated with isocaloric KD or standard diet of the same caloric intake for 4 weeks. Blood and urine were collected at baseline and after the sacrifice. SIRT1 was evaluated in serum, liver, and adipose tissue including VAT, subcutaneous adipose tissue (SAT) and brown adipose tissue (BAT). All organs were weighed dry and collected as follows: 1/2 in 10% Neutral Buffered Formalin Solution (for histology) and 1/2 dry at -80°C (for molecular analyses). After 4 weeks, despite the 1.7-fold higher caloric intake, KD-fed mice showed no significative changes in weight gain, VAT (g), SAT (g), glycemia (mg/dl) and TRG (mg/dl). Ketosis was efficaciously achieved in the treated group (p<0.001) and serum SIRT1 increased significantly compared to the controls under normal chow (p<0.05). Tissue SIRT1 expression increased both in VAT and SAT in mice under KD compared to normal chow group (p<0.05), while no differences were seen regarding liver and BAT. This study supports the hypothesis of a ketone body-mediated activation of SIRT1, specifically exerted in white adipose tissue, able to counteract the development of metabolic derangements. The possible cooperation between ketone bodies and SIRT1 could be of considerable interest in terms of promoting metabolic health.

Produzione scientifica

11573/1664670 - 2023 - Genome Editing and Obesity
Masi, D.; Tozzi, R.; Watanabe, M. - 02a Capitolo o Articolo
libro: Advances in Experimental Medicine and Biology - (978-981-19-5641-6; 978-981-19-5642-3)

11573/1687795 - 2023 - Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study
Puliani, G.; Sbardella, E.; Cozzolino, A.; Sada, V.; Tozzi, R.; Andreoli, C.; Fiorelli, M.; Di Biasi, C.; Corallino, D.; Balla, A.; Paganini, A. M.; Venneri, M. A.; Lenzi, A.; Lubrano, C.; Isidori, A. M. - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF OBESITY (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 948-955 - issn: 0307-0565 - wos: WOS:001035565900001 (2) - scopus: 2-s2.0-85165296514 (1)

11573/1687796 - 2023 - Correction: Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study
Puliani, Giulia; Sbardella, Emilia; Cozzolino, Alessia; Sada, Valentina; Tozzi, Rossella; Andreoli, Chiara; Fiorelli, Marco; Di Biasi, Claudio; Corallino, Diletta; Balla, Andrea; Paganini, Alessandro M; Venneri, Mary Anna; Lenzi, Andrea; Lubrano, Carla; Isidori, Andrea M - 01b Commento, Erratum, Replica e simili
rivista: INTERNATIONAL JOURNAL OF OBESITY (Basingstoke: Nature Publishing Group.) pp. - - issn: 1476-5497 - wos: WOS:001188414700001 (0) - scopus: 2-s2.0-85169102554 (0)

11573/1664774 - 2022 - Growth Hormone Secretory Capacity Is Associated with Cardiac Morphology and Function in Overweight and Obese Patients: A Controlled, Cross-Sectional Study
Gangitano, Elena; Barbaro, Giuseppe; Susi, Martina; Rossetti, Rebecca; Spoltore, Maria Elena; Masi, Davide; Tozzi, Rossella; Mariani, Stefania; Gnessi, Lucio; Lubrano, Carla - 01a Articolo in rivista
rivista: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 2420- - issn: 2073-4409 - wos: WOS:000840214700001 (3) - scopus: 2-s2.0-85136342459 (3)

11573/1629451 - 2022 - The Influence of Ketone Bodies on Circadian Processes Regarding Appetite, Sleep and Hormone Release: A Systematic Review of the Literature
Masi, D.; Spoltore, M. E.; Rossetti, R.; Watanabe, M.; Tozzi, R.; Caputi, A.; Risi, R.; Balena, A.; Gandini, O.; Mariani, S.; Spera, G.; Gnessi, L.; Lubrano, C. - 01a Articolo in rivista
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. 1410- - issn: 2072-6643 - wos: WOS:000783117500001 (14) - scopus: 2-s2.0-85127045255 (14)

11573/1622184 - 2022 - Circulating SIRT1 and Sclerostin Correlates with Bone Status in Young Women with Different Degrees of Adiposity
Tozzi, R.; Masi, D.; Cipriani, F.; Contini, S.; Gangitano, E.; Spoltore, M. E.; Barchetta, I.; Basciani, S.; Watanabe, M.; Baldini, E.; Ulisse, S.; Lubrano, C.; Gnessi, L.; Mariani, S. - 01a Articolo in rivista
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. - - issn: 2072-6643 - wos: WOS:000775633900001 (4) - scopus: 2-s2.0-85125183451 (5)

11573/1664775 - 2022 - Oxytocin correlates with body dysmorphic concerns and predicts weight loss in patients with obesity after a very low carbohydrate ketogenic diet
Tozzi, R.; Rossetti, R.; Basciani, S.; Masi, D.; Risi, R.; Balena, A.; Spoltore, M.; Watanabe, M.; Mariani, S.; Gnessi, L.; Lubrano, C. - 01h Abstract in rivista
rivista: DIABETOLOGIA (Berlin; Heidelberg: Springer.) pp. 268-268 - issn: 1432-0428 - wos: WOS:000835600800001 (0) - scopus: 2-s2.0-85136910121 (3)

11573/1645811 - 2022 - Reduction in Oxytocin levels predict body weight loss in patients with obesity after a very low carbohydrate ketogenic diet (VLCKD).
Tozzi, Rossella; Basciani, Sabrina; Rossetti, Rebecca; Balena, Angela; Masi, Davide; Risi, Renata; Veroi, Gabriele; Colonnello, Elena; Chiara Massari, Maria; Curreli, Mariaignazia; Gangitano, Elena; Watanabe, Mikiko; Mariani, Stefania; Gnessi &Amp;, Lucio; Lubrabno, Carla - 01h Abstract in rivista
rivista: ENDOCRINE ABSTRACTS (Bristol: Bioscientifica.) pp. - - issn: 1479-6848 - wos: (0) - scopus: (0)

11573/1662449 - 2022 - Ketogenic Diet Increases Serum and White Adipose Tissue SIRT1 Expression in Mice
Tozzi, Rossella; Campolo, Federica; Baldini, Enke; Venneri, Mary Anna; Lubrano, Carla; Ulisse, Salvatore; Gnessi, Lucio; Mariani, Stefania - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000902572400001 (1) - scopus: 2-s2.0-85144712477 (2)

11573/1654699 - 2022 - Ketone Bodies and SIRT1, Synergic Epigenetic Regulators for Metabolic Health: A Narrative Review
Tozzi, Rossella; Cipriani, Fiammetta; Masi, Davide; Basciani, Sabrina; Watanabe, Mikiko; Lubrano, Carla; Gnessi, Lucio; Mariani, Stefania - 01g Articolo di rassegna (Review)
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. 3145- - issn: 2072-6643 - wos: WOS:000839773300001 (12) - scopus: 2-s2.0-85136529673 (17)

11573/1607458 - 2022 - Rapid Weight Loss, Central Obesity Improvement and Blood Glucose Reduction Are Associated with a Stronger Adaptive Immune Response Following COVID-19 mRNA Vaccine
Watanabe, M.; Balena, A.; Masi, D.; Tozzi, R.; Risi, R.; Caputi, A.; Rossetti, R.; Spoltore, M. E.; Biagi, F.; Anastasi, E.; Angeloni, A.; Mariani, S.; Lubrano, C.; Tuccinardi, D.; Gnessi, L. - 01a Articolo in rivista
rivista: VACCINES (Basel: MDPI) pp. 79- - issn: 2076-393X - wos: WOS:000748052300001 (25) - scopus: 2-s2.0-85123275387 (28)

11573/1560506 - 2021 - GROWTH HORMONE SECRETORY CAPACITY AND BONE HEALTH INDICES IN OVERWEIGHT AND OBESE FEMALE PATIENTS
Gangitano, E.; Caputi, A.; Balena, A.; Rossetti, R.; Spoltore, M. E.; Tozzi, R.; Masi, D.; Risi, R.; Watanabe, M.; Mariani, S.; Gnessi, L.; Lubrano, C. - 04d Abstract in atti di convegno
congresso: X Congresso Nazionale SIO 2021 (Livorno)
libro: Atti del 10° congresso nazionale SIO - ()

11573/1540141 - 2021 - Ketogenic diet as a preventive and supportive care for covid-19 patients
Gangitano, E.; Tozzi, R.; Gandini, O.; Watanabe, M.; Basciani, S.; Mariani, S.; Lenzi, A.; Gnessi, L.; Lubrano, C. - 01g Articolo di rassegna (Review)
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. - - issn: 2072-6643 - wos: WOS:000633939300001 (23) - scopus: 2-s2.0-85102707865 (25)

11573/1613900 - 2021 - Ketogenic diet for obese COVID-19 patients: is respiratory disease a contraindication? A narrative review of the literature on ketogenic diet and respiratory function
Gangitano, E.; Tozzi, R.; Mariani, S.; Lenzi, A.; Gnessi, L.; Lubrano, C. - 01g Articolo di rassegna (Review)
rivista: FRONTIERS IN NUTRITION (Lausanne : Frontiers Media S.A., 2014-) pp. - - issn: 2296-861X - wos: WOS:000738706900001 (10) - scopus: 2-s2.0-85121631584 (11)

11573/1560515 - 2021 - Chondrosarcoma of the cavernous sinus treated with postoperative proton radiation therapy: case report and endocrinological follow up at 24 months
Masi, Davide; Risi, Renata; Balena, Angela; Caputi, Alessandra; Spoltore, Maria Elena; Rossetti, Rebecca; Watanabe, Mikiko; Tozzi, Rossella; Gangitano, Elena; Mariani, Stefania; Lubrano, Carla; Gnessi, Lucio - 04d Abstract in atti di convegno
congresso: 48° CONGRESSO NAZIONALE SIE 2021 (Roma)
libro: Atti in Congresso Nazionale SIE 2021 - ()

11573/1558060 - 2021 - Beyond weight loss in nonalcoholic fatty liver disease: the role of carbohydrate restriction
Risi, R.; Tozzi, R.; Watanabe, M. - 01g Articolo di rassegna (Review)
rivista: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (Rapid Science Publishers, London) pp. 349-353 - issn: 1363-1950 - wos: WOS:000661966200011 (8) - scopus: 2-s2.0-85107390712 (10)

11573/1560428 - 2021 - Evaluation of plasma levels of oxytocin in relation to body composition and cardiovascular risk parameters in obese and normal weight subjects.
Tozzi, R.; Rossetti, R.; Watanabe, M.; Gangitano, E.; Gnessi, L.; Mariani, S.; Lubrano, C. - 04d Abstract in atti di convegno
congresso: 41° Congresso Società Italiana di Endocrinologia (SIE) (Rome, Italy)
libro: 41° Congresso Società Italiana di Endocrinologia (SIE) - ()

11573/1474647 - 2021 - Case report: pituitary morphology and function are preserved in female patients with idiopathic intracranial hypertension under pharmacological treatment
Tozzi, Rossella; Moramarco, Antonietta; Watanabe, Mikiko; Balena, Angela; Caputi, Alessandra; Gangitano, Elena; Petrangeli, Elisa; Mariani, Stefania; Gnessi, Lucio; Lubrano, Carla - 01i Case report
rivista: FRONTIERS IN ENDOCRINOLOGY (Lausanne : Frontiers Research Foundation, 2010-) pp. - - issn: 1664-2392 - wos: WOS:000609254800001 (2) - scopus: 2-s2.0-85099727381 (2)

11573/1560429 - 2021 - Sirt1 and sclerostin: a pathophysiological connection between obesity and bone
Tozzi, Rossella; Spoltore, Maria Elena; Masi, Davide; Contini, Savina; Watanabe, Mikiko; Lubrano, Carla; Gnessi, Lucio; Mariani, Stefania - 04d Abstract in atti di convegno
congresso: 41° congresso nazionale Società Italiana di Endocrinologia (Roma; Italia)
libro: 41° congresso nazionale Società Italiana di Endocrinologia - ()

11573/1555926 - 2021 - Central obesity, smoking habit, and hypertension are associated with lower antibody titres in response to COVID‐19 mRNA vaccine
Watanabe, Mikiko; Balena, Angela; Tuccinardi, Dario; Tozzi, Rossella; Risi, Renata; Masi, Davide; Caputi, Alessandra; Rossetti, Rebecca; Spoltore, Maria Elena; Filippi, Valeria; Gangitano, Elena; Manfrini, Silvia; Mariani, Stefania; Lubrano, Carla; Lenzi, Andrea; Mastroianni, Claudio; Gnessi, Lucio - 01a Articolo in rivista
rivista: DIABETES/METABOLISM RESEARCH AND REVIEWS (John Wiley & Sons Limited:1 Oldlands Way, Bognor Regis, P022 9SA United Kingdom:011 44 1243 779777, EMAIL: cs-journals@wiley.co.uk, INTERNET: http://www.wiley.co.uk, Fax: 011 44 1243 843232) pp. - - issn: 1520-7552 - wos: WOS:000648919700001 (176) - scopus: 2-s2.0-85105501967 (190)

11573/1379722 - 2020 - Very Low-Calorie Ketogenic Diet: a safe and effective tool for weight loss in patients with obesity and mild kidney failure
Bruci, A; Tuccinardi, D; Tozzi, R; Balena, A; Santucci, S; Frontani, R; Mariani, S; Basciani, S; Spera, G; Gnessi, L; Lubrano, C; Watanabe, M - 01a Articolo in rivista
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. 1-12 - issn: 2072-6643 - wos: WOS:000522458700060 (106) - scopus: 2-s2.0-85078947095 (117)

11573/1499819 - 2020 - La capacità secretoria di GH costituisce un importante determinante del fenotipo metabolico nei pazienti sovrappeso ed obesi
Gangitano, Elena; Susi, Martina; Caputi, Alessandra; De Giorgi, Francesca; Tozzi, Rossella; Watanabe, Mikiko; Balena, Angela; Risi, Renata; Masi, Davide; Barbaro, Giuseppe; Gnessi, Lucio; Lubrano, Carla - 04f Poster
congresso: Incontri Italiani di Endocrinologia e Metabolismo (online)
libro: Incontri Italiani di Endocrinologia e Metabolismo - ()

11573/1463028 - 2020 - Blood sirt1 shows a coherent association with leptin and adiponectin in relation to the degree and distribution of adiposity: A study in obesity, normal weight and anorexia nervosa
Mariani, S.; Di Giorgio, M. R.; Rossi, E.; Tozzi, R.; Contini, S.; Bauleo, L.; Cipriani, F.; Toscano, R.; Basciani, S.; Barbaro, G.; Watanabe, M.; Valenti, A.; Cotugno, A.; Ancona, C.; Lubrano, C.; Gnessi, L. - 01a Articolo in rivista
rivista: NUTRIENTS (Basel, Switzerland: Molecular Diversity Preservation International (MDPI)) pp. 1-13 - issn: 2072-6643 - wos: WOS:000594509900001 (13) - scopus: 2-s2.0-85096225671 (16)

11573/1469793 - 2020 - Nickel sensitivity is associated with GH-IGF1 axis impairment and pituitary abnormalities on MRI in overweight and obese subjects
Risi, Renata; Masieri, Simonetta; Poggiogalle, Eleonora; Watanabe, Mikiko; Caputi, Alessandra; Tozzi, Rossella; Gangitano, Elena; Masi, Davide; Mariani, Stefania; Gnessi, Lucio; Lubrano, Carla - 01a Articolo in rivista
rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. - - issn: 1422-0067 - wos: WOS:000602759400001 (9) - scopus: 2-s2.0-85098148432 (8)

11573/1560496 - 2020 - Body composition, oxidative stress and bone strength parameters in patients with obesity: a cross sectional observational study
Watanabe, Mikiko; Raffa, Milena; Tozzi, Rossella; Gangitano, Elena; De Giorgi, Francesca; Caputi, Alessandra; Risi, Renata; Balena, Angela; Masi, Davide; Mariani, Stefania; Basciani, Sabrina; Petrangeli, Elisa; Gnessi, Lucio; Lubrano, Carla - 04d Abstract in atti di convegno
congresso: European and International Congress on Obesity (Dublin)
libro: European and International Congress on Obesity, Dublin, Ireland, May 2020 - ()

11573/1560503 - 2020 - Circulating lymphocytes characterization in obese subjects: a correlation with risk factors for cancer
Watanabe, Mikiko; Rossi, Vittoria; Tozzi, Rossella; Gangitano, Elena; De Giorgi, Francesca; Caputi, Alessandra; Risi, Renata; Balena, Angela; Masi, Davide; Mariani, Stefania; Basciani, Sabrina; Gnessi, Lucio; Lubrano, Carla - 04d Abstract in atti di convegno
congresso: Congresso Nazionale OPERA 2020 (Obesity, Programs of nutrition, Education, Research and Assessment of the best treatment) Workshop (Naples)
libro: Atti in OPERA (Obesity, Programs of nutrition, Education, Research and Assessment of the best treatment) Workshop - ()

11573/1381535 - 2020 - Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature
Watanabe, Mikiko; Tozzi, Rossella; Risi, Renata; Tuccinardi, Dario; Mariani, Stefania; Basciani, Sabrina; Spera, Giovanni; Lubrano, Carla; Gnessi, Lucio - 01g Articolo di rassegna (Review)
rivista: OBESITY REVIEWS (Blackwell Science, Oxford) pp. - - issn: 1467-7881 - wos: WOS:000521079100001 (113) - scopus: 2-s2.0-85082728751 (124)

11573/1499862 - 2019 - Oxytocin and emotional dysregulation in obese patients: a pilot study
Gangitano, Elena; Tozzi, Rossella; Watanabe, Mikiko; Basciani, Sabrina; Caputi, Alessandra; Costantini, Daniela; De Giorgi, Francesca; Mariani, Stefania; Gnessi, Lucio; Lubrano, Carla - 04d Abstract in atti di convegno
congresso: American Association of Clinical Endocrinologists AACE 28th Annual Scientific & Clinical Congress (Los Angeles, California)
libro: Endocrine Practice - ()

11573/1560431 - 2019 - Oxytocin levels correlate with metabolic syndrome in obese patients
Tozzi, R.; Gangitano, E.; Watanabe, M.; Basciani, S.; Caputi, A.; Costantini, D.; De Giorgi, F.; Mariani, S.; Gnessi, L.; Lubrano, C. - 04f Poster
congresso: 40 ° Congresso Nazionale della Società Italiana di Endocrinologia (SIE) (Rome; Italy)
libro: 40 ° Congresso Nazionale della Società Italiana di Endocrinologia (SIE) - ()

11573/1560483 - 2019 - Binge eating disorder is associated with lower glucose levels three hours after an oral glucose tolerance test
Watanabe, M.; Tozzi, R.; De Giorgi, F.; Caputi, A.; Poggiogalle, E.; Risi, R.; Balena, A.; Gangitano, E.; Basciani, S.; Mariani, S.; Gnessi, L.; Lubrano, C. - 01h Abstract in rivista
rivista: OBESITY FACTS (Basel: S. Karger AG) pp. 1-290 - issn: 1662-4025 - wos: (0) - scopus: (0)

11573/1250530 - 2018 - Impatto dei farmaci modulatori della proteina CFTR sulle alterazioni dell’asse GH – IGF-1 in pazienti adulti affetti da Fibrosi Cistica
Pascucci, C; De Biase, Riccardo Valerio; Watanabe, M; Tozzi, R; Gangitano, E; Di Giorgio, Maria Rosaria; Vari, M; Mariani, S; Gnessi, L; Lubrano, C - 04d Abstract in atti di convegno
congresso: Incontri Italiani di Endocrinologia e Metabolismo 2018 (Bari; Italia)
libro: atti di Convegno Incontri Italiani di Endocrinologia e Metabolismo 2018 - ()

11573/1250536 - 2018 - Secrezione di GH e morfologia ipofisaria in pazienti obesi
Tozzi, R; Watanabe, M; Pascucci, C; De Giorgi, Francesca; Costantini, D; Caputi, Alessandra; Vari, M; Contini, S; Petrangeli, E; Mariani, S; Isidori, Am; Lubrano, C - 04d Abstract in atti di convegno
congresso: Incontri Italiani di Endocrinologia e Metabolismo 2018 (Bari; Italia)
libro: atti di Convegno Incontri Italiani di Endocrinologia e Metabolismo 2018 - ()

11573/1250541 - 2018 - Bmd/bmi ratio and trabecular bone score: new potential tools to assess the risk of fracture in obese patients
Watanabe, M; Costantini, D; Tozzi, Rossella; De Giorgi, Roberta; Gangitano, E; Poggiogalle, E; Mariani, S; Basciani, S; Petrangeli, E; Gnessi, L; Lubrano, C - 04d Abstract in atti di convegno
congresso: AACE 2018 (Boston, MA; USA)
libro: Abstract Book AACE 2018 - ()

11573/1136601 - 2018 - Overweight and obese patients with nickel allergy have a worse metabolic profile compared to weight matched non-allergic individuals
Watanabe, Mikiko; Masieri, S; Costantini, D; Tozzi, R; De Giorgi, F; Gangitano, Elena; Tuccinardi, D; Poggiogalle, E; Mariani, S; Basciani, S; Petrangeli, Elisa; Gnessi, L; Lubrano, C. - 01a Articolo in rivista
rivista: PLOS ONE (San Francisco, CA : Public Library of Science) pp. - - issn: 1932-6203 - wos: WOS:000443001700021 (28) - scopus: 2-s2.0-85052611041 (28)

11573/1560423 - 2017 - Obesity, cardiomyopathy and anabolic hormones
Gangitano, Elena; Costantini, Daniela; Tozzi, Rossella; De Giorgi, Francesca; Poggiogalle, Eleonora; Mariani, Stefania; Petrangeli, Elisa; Donini, Lorenzo Maria; Barbaro, Giuseppe; Gnessi, Lucio; Lubrano, Carla - 01h Abstract in rivista
rivista: ENDOCRINE ABSTRACTS (Bristol: Bioscientifica.) pp. - - issn: 1479-6848 - wos: (0) - scopus: (0)

11573/1560446 - 2017 - Osteoprotegerin levels are related to endothelial dysfunction in obese women
Tozzi, R.; Rossi, Fm.; Bertone, C.; Anzuini, A.; Gangitano, E.; Basciani, S.; Mariani, S.; Lenzi, A.; Gnessi, L.; Lubrano, Carla - 04f Poster
congresso: 39° Congresso Nazionale della Società Italiana di Endocrinologia (Rome; Italy)
libro: 39° Congresso Nazionale della Società Italiana di Endocrinologia - ()

11573/1250527 - 2017 - Sensibilità al nickel in una popolazione italiana sovrappeso ed obesa
Watanabe, M; Petrangeli, E; Mariani, S; Tozzi, R; De Giorgi, F; Costantini, D; Vari, M; Gangitano, E; Lenzi, A; Gnessi, L; Lubrano, C - 04d Abstract in atti di convegno
congresso: 1° Meeting Club SIE Endocrinologia Ambientale (roma;Italia)
libro: Atti di Convegno 1° Meeting Club SIE Endocrinologia Ambientale - ()

11573/1250520 - 2017 - Metabolically Healthy Obesity: an Endocrinological Issue?
Watanabe, M; Poggiogalle, E; Tozzi, R; Basciani, S; Mariani, S; Petrangeli, E; Donini, Lm; Lenzi, A; Gnessi, L; Lubrano, C - 04d Abstract in atti di convegno
congresso: XXXIX Congresso Nazionale SIE (Roma;Italia)
libro: atti di convegno XXXIX Congresso Nazionale SIE - ()

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