ROMANO SILVESTRI

Full professor


email: romano.silvestri@uniroma1.it
phone: 0649113800
building: CU019
room: 104

Prof. Romano Silvestri is Full Professor of Medicinal Chemistry at the Sapienza University of Rome, Italy. He graduated cum laude from Sapienza University and completed his PhD studies in Pharmaceutical Sciences by the same University. Since being recruited to the Department of Pharmaceutical Studies, he became Assistant Professor (1991-1998) and Associate Professor (1998-2010). In 2008 he moved to Department of Drug Chemistry and Technologies, and in 2010 became Full Professor. He was visting professor at Emory University, Department of Chemistry, Atlanta, USA (prof. Dennis Liotta), and at King’s College, London (UK).
The research projects are mainly focused on the drug design and synthesis of new biologically active chemical entities in the areas of antitumor, infective and SNC drugs. The drug design is based on molecular models performed by the internal computational unit New procedures for themicrowave-assisted synthesis and the highly automated purification of relevant pharmaceutical molecules are also developed.
Scopus metric overview 01-Mar-2023: 196 publications, 5870 citations, H-index 40

Research products

11573/1738008 - 2024 - Induction of ferroptosis by new pyrrole tubulin assembly inhibitors
La Regina, G.; Hamel, E.; Liu, T.; Canettieri, G.; Silvestri, R. - 04b Atto di convegno in volume
conference: The 4th Molecules Medicinal Chemistry Symposium (Barcellona, Spagna)
book: Abstract Book - ()

11573/1710165 - 2024 - Metabolic Rewiring in Cancer: Small Molecule Inhibitors in Colorectal Cancer Therapy
Masci, Domiziana; Puxeddu, Michela; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 2110-2110 - issn: 1420-3049 - wos: WOS:001219954100001 (3) - scopus: 2-s2.0-85192770247 (4)

11573/1728002 - 2024 - Targeting CBP and p300. Emerging anticancer agents
Masci, Domiziana; Puxeddu, Michela; Silvestri, Romano; La Regina, Giuseppe - 01g Articolo di rassegna (Review)
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-22 - issn: 1420-3049 - wos: WOS:001332484400001 (0) - scopus: 2-s2.0-85206558839 (0)

11573/1726988 - 2024 - 4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses
Puxeddu, M.; Donalisio, M.; Bugert, J. J.; Corona, A.; Cocomazzi, P.; Milani, M.; Hucke, F.; Arduino, I.; Esposito, F.; Moretti, P.; Ortore, M. G.; Nalli, M.; Manetto, S.; Mazzoccanti, G.; Bigogno, C.; Dondio, G.; Scio', P.; Coluccia, A.; Fracella, M.; Antonelli, G.; Lembo, D.; Tramontano, E.; Silvestri, R.; Mastrangelo, E.; La Regina, G. - 01a Articolo in rivista
paper: ACS INFECTIOUS DISEASES (Washington, DC : American Chemical Society, 2015-) pp. 3158-3175 - issn: 2373-8227 - wos: WOS:001284160100001 (1) - scopus: 2-s2.0-85200391860 (1)

11573/1727020 - 2024 - Development of N-(4-(1 H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability
Puxeddu, Michela; Ling, Lele; Ripa, Silvia; D'ambrosio, Michele; Nalli, Marianna; Parisi, Anastasia; Scio', Pietro; Coluccia, Antonio; Granese, Arianna; Santelli, Martina; Masci, Domiziana; Cuřínová, Petra; Naro, Chiara; Sette, Claudio; Pastore, Arianna; Stornaiuolo, Mariano; Bigogno, Chiara; Dondio, Giulio; Di Magno, Laura; Canettieri, Gianluca; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 20298-20314 - issn: 1520-4804 - wos: WOS:001350014100001 (0) - scopus: 2-s2.0-85208709914 (1)

11573/1715709 - 2024 - New Potent EV-A71 Antivirals Targeting Capsid
Roux, Hugo; Touret, Franck; Coluccia, Antonio; Khoumeri, Omar; Majdi, Chaimae; Scio, Pietro; Silvestri, Romano; Vanelle, Patrice; Manon Roche, And - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-18 - issn: 0223-5234 - wos: WOS:001286467500001 (1) - scopus: 2-s2.0-85199915542 (1)

11573/1726911 - 2023 - New potential yeast probiotic strains isolated from Buffalo milk whey
Bonfanti, Andrea; Silvestri, Romano; Novellino, Ettore; Maisto, Maria; Tenore, Giancarlo; Mazzoni, Cristina - 04f Poster
conference: 8th Conference on Physiology of Yeasts and Filamentous Fungi (PYFF8) (Cork)
book: https://efbiotechnology.org/images/uploads/PYFF8_Abstract_book.pdf - ()

11573/1680491 - 2023 - Targeting the Grb2 cSH3 domain: design, synthesis and biological evaluation of the first series of modulators
Bufano, Marianna; Puxeddu, Michela; Nalli, Marianna; La Regina, Giuseppe; Toto, Angelo; Liberati, Francesca Romana; Paone, Alessio; Cutruzzolà, Francesca; Masci, Domiziana; Bigogno, Chiara; Dondio, Giulio; Silvestri, Romano; Gianni, Stefano; Coluccia, Antonio - 01a Articolo in rivista
paper: BIOORGANIC CHEMISTRY (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 106607- - issn: 0045-2068 - wos: WOS:001007153500001 (2) - scopus: 2-s2.0-85159597372 (2)

11573/1667362 - 2023 - Toll-like receptor 4-dependent platelet-related thrombosis in SARS-CoV-2 infection
Carnevale, Roberto; Cammisotto, Vittoria; Bartimoccia, Simona; Nocella, Cristina; Castellani, Valentina; Bufano, Marianna; Loffredo, Lorenzo; Sciarretta, Sebastiano; Frati, Giacomo; Coluccia, Antonio; Silvestri, Romano; Ceccarelli, Giancarlo; Oliva, Alessandra; Venditti, Mario; Pugliese, Francesco; Maria Mastroianni, Claudio; Turriziani, Ombretta; Leopizzi, Martina; D'amati, Giulia; Pignatelli, Pasquale; Violi, Francesco - 01a Articolo in rivista
paper: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320 PRimo editore: Baltimore, Md. : Grune & Stratton, c1953-) pp. 290-305 - issn: 0009-7330 - wos: WOS:000924202600003 (19) - scopus: 2-s2.0-85147310768 (23)

11573/1696168 - 2023 - Rimonabant-Based Compounds Bearing Hydrophobic Amino Acid Derivatives as Cannabinoid Receptor Subtype 1 Ligands
Dvorácskó, Szabolcs; Dimmito, Marilisa Pia; Sebastiani, Jessica; La Regina, Giuseppe; Silvestri, Romano; Pieretti, Stefano; Stefanucci, Azzurra; Tömböly, Csaba; Mollica, Adriano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 479-486 - issn: 1948-5875 - wos: WOS:000948759200001 (1) - scopus: 2-s2.0-85149790546 (1)

11573/1669812 - 2023 - A novel validated UHPLC method for the estimation of rosuvastatin and its complete impurity profile in tablet formulations
Mammone, F. R.; Zanitti, L.; Puxeddu, M.; La Regina, G.; Silvestri, R.; Borioni, A.; Cirilli, Roberto - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-12 - issn: 1420-3049 - wos: WOS:000909218800001 (7) - scopus: 2-s2.0-85145678833 (7)

11573/1725621 - 2023 - Chemo- and enantio-selective reversed-phase HPLC analysis of rosuvastatin using a cellulose-based chiral stationary phase in gradient elution mode
Mammone, Francesca Romana; Rotundo, Paola; Ferretti, Rosella; Puxeddu, Michela; Silvestri, Romano; Cirilli, Roberto - 01a Articolo in rivista
paper: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (Oxford ; New York : Pergamon Press Amsterdam : Elsevier Science) pp. 1-6 - issn: 0731-7085 - wos: WOS:000982097700001 (8) - scopus: 2-s2.0-85146057165 (7)

11573/1696165 - 2023 - Recent advances in drug discovery for Triple-Negative Breast cancer treatment
Masci, Domiziana; Naro, Chiara; Puxeddu, Michela; Urbani, Andrea; Sette, Claudio; La Regina, Giuseppe; Silvestri, Romano - 01g Articolo di rassegna (Review)
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:001120971200001 (6) - scopus: 2-s2.0-85177764631 (6)

11573/1696179 - 2023 - 4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a novel carbonic anhydrase and Wnt/β-Catenin signaling pathway dual-targeting inhibitor with potent activity against multidrug resistant cancer cells
Masci, Domiziana; Puxeddu, Michela; Di Magno, Laura; D'ambrosio, Michele; Parisi, Anastasia; Nalli, Marianna; Bai, Ruoli; Coluccia, Antonio; Sciò, Pietro; Orlando, Viviana; D'angelo, Sara; Biagioni, Stefano; Urbani, Andrea; Hamel, Ernest; Nocentini, Alessio; Filiberti, Serena; Turati, Marta; Ronca, Roberto; Kopecka, Joanna; Riganti, Chiara; Fionda, Cinzia; Bordone, Rosa; Della Rocca, Giorgia; Canettieri, Gianluca; Supuran, Claudiu T; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 14824-14842 - issn: 1520-4804 - wos: WOS:001096765200001 (4) - scopus: 2-s2.0-85176509722 (6)

11573/1710164 - 2023 - Biological evaluation of [4‐(4‐aminophenyl)‐1‐(4‐fluorophenyl)‐1H‐pyrrol‐3‐yl](3,4,5‐trimethoxyphenyl)methanone as potential antineoplastic agent in 2D and 3D breast cancer models
Mazzoccoli, Carmela; Crispo, Fabiana; Laurenzana, Ilaria; Pietrafesa, Michele; Sisinni, Lorenza; Lerose, Rosa; Telesca, Donatella; Milella, Maria R.; Liu, Te; Della Sala, Gerardo; Sebastiani, Jessica; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 2300354-2300354 - issn: 0365-6233 - wos: WOS:001051448000001 (0) - scopus: 2-s2.0-85168515388 (0)

11573/1684557 - 2023 - Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent
Nalli, Marianna; Di Magno, Laura; Wen, Yichao; Liu, Xin; D’Ambrosio, Michele; Puxeddu, Michela; Parisi, Anastasia; Sebastiani, Jessica; Sorato, Andrea; Coluccia, Antonio; Ripa, Silvia; Di Pastena, Fiorella; Capelli, Davide; Montanari, Roberta; Masci, Domiziana; Urbani, Andrea; Naro, Chiara; Sette, Claudio; Orlando, Viviana; D’Angelo, Sara; Biagioni, Stefano; Bigogno, Chiara; Dondio, Giulio; Pastore, Arianna; Stornaiuolo, Mariano; Canettieri, Gianluca; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (Washington DC: American Chemical Society) pp. 1087-1103 - issn: 2575-9108 - wos: WOS:001022871100001 (3) - scopus: 2-s2.0-85164931909 (2)

11573/1669754 - 2023 - RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo
Sebastiani, J.; Puxeddu, M.; Nalli, M.; Bai, R.; Altieri, L.; Rovella, P.; Gaudio, E.; Trisciuoglio, D.; Spriano, F.; Lavia, P.; Fionda, C.; Masci, D.; Urbani, A.; Bigogno, C.; Dondio, G.; Hamel, E.; Bertoni, F.; Silvestri, R.; La Regina, G. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. - - issn: 1768-3254 - wos: WOS:000902003000001 (7) - scopus: 2-s2.0-85145425603 (7)

11573/1645691 - 2022 - Exploring CCRL2 chemerin binding using accelerated molecular dynamics
Bufano, M.; Laffranchi, M.; Sozzani, S.; Raimondo, D.; Silvestri, R.; Coluccia, A. - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 1-7 - issn: 0887-3585 - wos: WOS:000788507200001 (8) - scopus: 2-s2.0-85128889142 (8)

11573/1622472 - 2022 - Single-run chemo- and enantio-selective high-performance liquid chromatography separation of tramadol and its principal metabolite, O-desmethyltramadol, using a chlorinated immobilized amylose-based chiral stationary phase under multimodal elution conditions
Cantatore, C.; La Regina, G.; Ferretti, R.; Silvestri, R.; Cirilli, R. - 01a Articolo in rivista
paper: SEPARATION SCIENCE PLUS (Hoboken New Jersey : John Wiley) pp. 99-104 - issn: 2573-1815 - wos: WOS:000757674000001 (2) - scopus: 2-s2.0-85147396296 (2)

11573/1616528 - 2022 - Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor
Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe La; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Musto, Giorgia; Badolati, Nadia; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cirilli, Roberto; Cutruzzolà, Francesca; Gianni, Stefano; Stornaiuolo, Mariano; Silvestri, Romano - 01a Articolo in rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000773498900001 (7) - scopus: 2-s2.0-85131007159 (7)

11573/1660747 - 2022 - Discovery of novel human lactate dehydrogenase inhibitors. Structure-based virtual screening studies and biological assessment
Di Magno, L; Coluccia, A; Bufano, M; Ripa, S; La Regina, G; Nalli, M; Di Pastena, F; Canettieri, G; Silvestri, R; Frati, L - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-12 - issn: 0223-5234 - wos: WOS:000834164000003 (8) - scopus: 2-s2.0-85134696311 (8)

11573/1662369 - 2022 - Efficacy and safety of a new food supplement in the treatment of functional dyspepsia. An open study
Innocenti, Matteo; Silvestri, Romano; Ceracchi, Maurizio; Silvestrini, Bruno - 01a Articolo in rivista
paper: AGRO FOOD INDUSTRY HI-TECH (Milano : Teknoscienze srl) pp. 42-47 - issn: 1722-6996 - wos: (0) - scopus: (0)

11573/1669809 - 2022 - Emerging direct targeting β-catenin agents
Nalli, M.; Masci, D.; Urbani, A.; La Regina, G.; Silvestri, R. - 01g Articolo di rassegna (Review)
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 1-15 - issn: 1420-3049 - wos: WOS:000887474600001 (5) - scopus: 2-s2.0-85142604566 (5)

11573/1622488 - 2022 - Modulating undruggable targets to overcome cancer therapy resistance
Passirani, C.; Vessieres, A.; La Regina, G.; Link, W.; Silvestri, R. - 01a Articolo in rivista
paper: DRUG RESISTANCE UPDATES (W B Saunders Company:Fulfillment Department, The Curtis Center, Independence Square West:Philadelphia, PA 19106:(800)654-2452, (215)238-7800, EMAIL: wbspcs@harcourt.com, INTERNET: http://elsevierhealth.com, Fax: (215)238-6445) pp. - - issn: 1368-7646 - wos: WOS:000758804000001 (18) - scopus: 2-s2.0-85124496115 (18)

11573/1664745 - 2022 - Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
Puxeddu, Michela; Wu, Jianchao; Bai, Ruoli; D’Ambrosio, Michele; Nalli, Marianna; Coluccia, Antonio; Manetto, Simone; Ciogli, Alessia; Masci, Domiziana; Urbani, Andrea; Fionda, Cinzia; Coni, Sonia; Bordone, Rosa; Canettieri, Gianluca; Bigogno, Chiara; Dondio, Giulio; Hamel, Ernest; Liu, Te; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 15805-15818 - issn: 0022-2623 - wos: WOS:000888017600001 (16) - scopus: 2-s2.0-85142634063 (15)

11573/1587169 - 2021 - Enantiomerization barrier of 1-[2-(2-methyl-2-methoxycarbonylacetamido) benzenesulfonyl]-1h-pyrrole studied by enantioselective dynamic HPLC, classical off column technique and computational approach
Buonsenso, Fabio; Cirilli, Roberto; Silvestri, Romano; Pierini, Marco - 04f Poster
conference: Merck Young Chemists' Symposium XX edition (Rimini)
book: Proceedings of the Merck Young Chemists' Symposium XX edition - (978-88-94952-25-4)

11573/1554505 - 2021 - CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme
Daniele, S.; La Pietra, V.; Piccarducci, R.; Pietrobono, D.; Cavallini, C.; D'amore, V. M.; Cerofolini, L.; Giuntini, S.; Russomanno, P.; Puxeddu, M.; Nalli, M.; Pedrini, M.; Fragai, M.; Luchinat, C.; Novellino, E.; Taliani, S.; La Regina, G.; Silvestri, R.; Martini, C.; Marinelli, L. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 1-17 - issn: 0014-2999 - wos: WOS:000628752700009 (17) - scopus: 2-s2.0-85102892586 (17)

11573/1554566 - 2021 - RS4651 suppresses lung fibroblast activation via the TGF-β1/SMAD signalling pathway
Li, S.; Xu, A.; Li, Y.; Tan, C.; La Regina, G.; Silvestri, R.; Wang, H.; Qi, W. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 1-10 - issn: 0014-2999 - wos: WOS:000657380100001 (6) - scopus: 2-s2.0-85105328489 (6)

11573/1573217 - 2021 - RS-5645 attenuates inflammatory cytokine storm induced by SARS-CoV-2 spike protein and LPS by modulating pulmonary microbiota
Liu, T.; Wu, J.; Han, C.; Gong, Z.; La Regina, G.; Chen, J.; Dou, F.; Silvestri, R.; Chen, C.; Yu, Z. - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (Lake Haven, N.S.W., Australia : Ivyspring International, c2004-) pp. 3305-3319 - issn: 1449-2288 - wos: WOS:000685459400004 (10) - scopus: 2-s2.0-85113771922 (10)

11573/1604509 - 2021 - Emerging therapeutic agents for colorectal cancer
Nalli, M.; Puxeddu, M.; La Regina, G.; Gianni, S.; Silvestri, R. - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. 7463-7463 - issn: 1420-3049 - wos: WOS:000736380500001 (21) - scopus: 2-s2.0-85121522712 (21)

11573/1579282 - 2021 - Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer
Nardella, Caterina; Visconti, Lorenzo; Malagrinò, Francesca; Pagano, Livia; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. - - issn: 1745-6150 - wos: WOS:000706722300001 (14) - scopus: 2-s2.0-85117321017 (16)

11573/1738007 - 2021 - New pyrroles derivatives as anti-glioblastoma and anti-chronic myeloid leukemia agents
Puxeddu, M.; Sebastiani, J.; Coluccia, A.; Bufano, M.; Hamel, E.; Liu, T.; Silvestri, R.; La Regina, G. - 04b Atto di convegno in volume
conference: XXVII Congresso Nazionale della Società Chimica Italiana (Online meeting)
book: Abstract Book - ()

11573/1554523 - 2021 - Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia
Puxeddu, M.; Shen, H.; Bai, R.; Coluccia, A.; Bufano, M.; Nalli, M.; Sebastiani, J.; Brancaccio, D.; Da Pozzo, E.; Tremolanti, C.; Martini, C.; Orlando, V.; Biagioni, S.; Sinicropi, M. S.; Ceramella, J.; Iacopetta, D.; Coluccia, A. M. L.; Hamel, E.; Liu, T.; Silvestri, R.; La Regina, G. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-18 - issn: 0223-5234 - wos: WOS:000661282500029 (15) - scopus: 2-s2.0-85106600720 (16)

11573/1662370 - 2021 - A method to measure the barrier effect of drugs and its application in the study of hydrolyzed collagen
Silvestrini, Bruno; Silvestri, Romano; Cheng, C. Y.; Ceracchi, Maurizio; Innocenti, Matteo - 01a Articolo in rivista
paper: AGRO FOOD INDUSTRY HI-TECH (Milano : Teknoscienze srl) pp. 12-16 - issn: 1722-6996 - wos: (0) - scopus: (0)

11573/1604507 - 2021 - Discovery of a novel class of norovirus inhibitors with high barrier of resistance
Van Dycke, J.; Puxeddu, M.; La Regina, G.; Mastrangelo, E.; Tarantino, D.; Rymenants, J.; Sebastiani, J.; Nalli, M.; Matthijnssens, J.; Neyts, J.; Silvestri, R.; Rocha-Pereira, J. - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel: MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000711764700001 (1) - scopus: 2-s2.0-85116529403 (2)

11573/1436420 - 2020 - Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics
Bufano, M.; Laudette, M.; Blondeau, J. -P.; Lezoualc'h, F.; Nalli, M.; Silvestri, R.; Brancale, A.; Coluccia, A. - 01a Articolo in rivista
paper: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ -Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. - - issn: 0920-654X - wos: WOS:000551348400001 (2) - scopus: 2-s2.0-85088437648 (1)

11573/1487109 - 2020 - HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53
Capdevielle, Caroline; Desplat, Angelique; Charpentier, Justine; Sagliocco, Francis; Thiebaud, Pierre; Theze, Nadine; Fedou, Sandrine; Hooks, Katarzyna B.; Silvestri, Romano; Guyonnet-Duperat, Veronique; Petrel, Melina; Raymond, Anne-Aurelie; Dupuy, Jean-William; Grosset, Christophe F.; Hagedorn, Martin - 01a Articolo in rivista
paper: NEURO-ONCOLOGY (Carden Jennings Pub.) pp. 550-562 - issn: 1522-8517 - wos: WOS:000537427200015 (10) - scopus: 2-s2.0-85083545548 (10)

11573/1436287 - 2020 - Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage
Coluccia, A.; Puxeddu, M.; Nalli, M.; Wei, C. K.; Wu, Y. H.; Mastrangelo, E.; Elamin, T.; Tarantino, D.; Bugert, J. J.; Schreiner, B.; Nolte, J.; Schwarze, F.; La Regina, G.; Lee, J. C.; Silvestri, R. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 1869-1874 - issn: 1948-5875 - wos: WOS:000580567800013 (21) - scopus: 2-s2.0-85089122411 (20)

11573/1451071 - 2020 - Sulfonamide inhibitors of beta-catenin signaling as anticancer agents with different output on c-Myc
Di Magno, Laura; Di Pastena, Fiorella; Puxeddu, Michela; La Regina, Giuseppe; Coluccia, Antonio; Ciogli, Alessia; Manetto, Simone; Maroder, Marella; Canettieri, Gianluca; Silvestri, Romano; Nalli, Marianna - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 2264-2268 - issn: 1860-7179 - wos: WOS:000577594900001 (7) - scopus: 2-s2.0-85092511066 (7)

11573/1033380 - 2020 - Selenotriapine - an isostere of the most studied thiosemicarbazone with pronounced pro-apoptotic activity, low toxicity and ability to challenge phenotype reprogramming of 3-D mammary adenocarcinoma tumors
Filipović, N. R.; Bjelogrlić, S. K.; Pelliccia, S.; Jovanović, V. B.; Kojić, M.; Senćanski, M.; La Regina, G.; Silvestri, R.; Muller, C. D.; Todorović, T. R. - 01a Articolo in rivista
paper: ARABIAN JOURNAL OF CHEMISTRY (Amsterdam : Elsevier) pp. 1466-1489 - issn: 1878-5352 - wos: WOS:000505076000109 (6) - scopus: 2-s2.0-85037552505 (7)

11573/1338475 - 2020 - Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors
La Regina, G.; Puxeddu, M.; Nalli, M.; Vullo, D.; Gratteri, P.; Supuran, C. T.; Nocentini, A.; Silvestri, R. - 01f Lettera, Nota
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 633-637 - issn: 1948-5875 - wos: WOS:000535281200005 (4) - scopus: 2-s2.0-85075123548 (4)

11573/1456152 - 2020 - Targeting the interaction between the SH3 domain of Grb2 and Gab2
Malagrinò, Francesca; Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe; Puxeddu, Michela; Toto, Angelo; Visconti, Lorenzo; Paone, Alessio; Magnifico, Maria Chiara; Troilo, Francesca; Cutruzzolà, Francesca; Silvestri, Romano; Gianni, Stefano - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 2435- - issn: 2073-4409 - wos: WOS:000592940700001 (7) - scopus: 2-s2.0-85096028884 (7)

11573/1436323 - 2020 - New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains
Nalli, M.; Armijos Rivera, J. I.; Masci, D.; Coluccia, A.; Badia, R.; Riveira-Muñoz, E.; Brambilla, A.; Cinquina, E.; Turriziani, O.; Falasca, F.; Catalano, M.; Limatola, C.; Esté, J. A.; Maga, G.; Silvestri, R.; Crespan, E.; La Regina, G. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000600384300005 (14) - scopus: 2-s2.0-85090028457 (14)

11573/1338485 - 2020 - Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies
Puxeddu, M.; Shen, H.; Bai, R.; Coluccia, A.; Nalli, M.; Mazzoccoli, C.; Da Pozzo, E.; Cavallini, C.; Martini, C.; Orlando, V.; Biagioni, S.; Mazzoni, C.; Coluccia, A. M. L.; Hamel, E.; Liu, T.; Silvestri, R.; La Regina, G. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000503099900046 (7) - scopus: 2-s2.0-85075503012 (8)

11573/1452337 - 2020 - Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites
Scala, R.; Di Matteo, A.; Coluccia, A.; Lo Sciuto, A.; Federici, L.; Travaglini-Allocatelli, C.; Visca, P.; Silvestri, R.; Imperi, F. - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. 11276- - issn: 2045-2322 - wos: WOS:000548559600037 (4) - scopus: 2-s2.0-85087717252 (5)

11573/1336446 - 2020 - Design, synthesis and discovery of novel N,N'-carbazoyl-aryl-urea inhibitors of Zika NS5 methyltransferase and virus replication.
Spizzichino, S; Mattedi, G; Lauder, K; Valle, C; Aouadi, W; Canard, B; Decroly, E; Kaptein, Sjf; Neyts, J; Graham, C; Sule, Z; Barlow, Dj; Silvestri, R; Castagnolo, D. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 385-390 - issn: 1860-7187 - wos: WOS:000505817500001 (14) - scopus: 2-s2.0-85078073812 (18)

11573/1282534 - 2019 - Nox2-mediated platelet activation by glycoprotein (GP) VI: Effect of rivaroxaban alone and in combination with aspirin
Cammisotto, Vittoria; Carnevale, Roberto; Nocella, Cristina; Stefanini, Lucia; Bartimoccia, Simona; Coluccia, Antonio; Silvestri, Romano; Pignatelli, Pasquale; Pastori, Daniele; Violi, Francesco - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 111-118 - issn: 0006-2952 - wos: WOS:000466060000011 (18) - scopus: 2-s2.0-85061548638 (19)

11573/1223718 - 2019 - Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents
Coluccia, A.; La Regina, G.; Naccarato, V.; Nalli, M.; Orlando, V.; Biagioni, S.; De Angelis, M. L.; Baiocchi, M.; Gautier, C.; Gianni, S.; Di Pastena, F.; Di Magno, L.; Canettieri, G.; Coluccia, A. M. L.; Silvestri, R. - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 499-503 - issn: 1948-5875 - wos: WOS:000464767700019 (14) - scopus: 2-s2.0-85064264813 (14)

11573/1278685 - 2019 - Nitrogen donor ligands and their coordination compounds as a tool for treatment of multi drug resistant tumors
Filipović, Nr; Todorović, Tr; Bjelogrlić, S; Silvestri, R; La Regina, G; Pelliccia, S; Padron, Jm; Schembri-Wismayer, P; Donard, M; Gulea, M; Muler, Cd - 04f Poster
conference: New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours - First Working-Group Meeting (Torino (TO))
book: Abstract Book - ()

11573/1223723 - 2019 - Towards modern anticancer agents that interact with tubulin
La Regina, G.; Coluccia, A.; Naccarato, V.; Silvestri, R. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (Amsterdam Netherlands: Elsevier BV) pp. 58-68 - issn: 0928-0987 - wos: WOS:000460399800006 (41) - scopus: 2-s2.0-85061343987 (43)

11573/1338512 - 2019 - Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Bufano, M.; Nalli, M.; Coluccia, A.; Orlando, V.; Canettieri, G.; Gianni, S.; Silvestri, R. - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()

11573/1338507 - 2019 - Small molecule inhibitors of kdm5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing JARID1B
La Regina, G.; Naccarato, V.; Masci, D.; Puxeddu, M.; Nalli, M.; Coluccia, A.; Negri, R.; Silvestri, R. - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()

11573/1278679 - 2019 - New anti-cancer agents through an interaction with tubulin
La Regina, G; Coluccia, A; Naccarato, V; Silvestri, R. - 04f Poster
conference: New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours - First Working-Group Meeting (Torino (TO))
book: Abstract Book - ()

11573/1278540 - 2019 - First in class pdz1 targeting NHERF1 inhibitors as anticancer agents
La Regina, Giuseppe; Naccarato, Valentina; Puxeddu, Michela; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 12th European Workshop in Drug Design (Siena)
book: Book of Abstract - ()

11573/1338740 - 2019 - Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress
Laudette, Marion; Coluccia, Antonio; Sainte-Marie, Yannis; Solari, Andrea; Fazal, Loubina; Sicard, Pierre; Silvestri, Romano; Mialet-Perez, Jeanne; Pons, Sandrine; Ghaleh, Bijan; Blondeau, Jean-Paul; Frank Lezoualc’H, And - 01a Articolo in rivista
paper: CARDIOVASCULAR RESEARCH (Oxford: Oxford University Press Amsterdam: Elsevier London: British Medical Association, 1967-) pp. 1766-1777 - issn: 0008-6363 - wos: WOS:000491246600015 (31) - scopus: 2-s2.0-85072535959 (32)

11573/1284052 - 2019 - Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: structure-activity relationships and mode of action studies
Masci, D.; Hind, C.; Islam, M. K.; Toscani, A.; Clifford, M.; Coluccia, A.; Conforti, Irene; Touitou, M.; Memdouh, S.; Wei, X.; La Regina, G.; Silvestri, R.; Sutton, J. M.; Castagnolo, D. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 500-514 - issn: 0223-5234 - wos: WOS:000480664100037 (27) - scopus: 2-s2.0-85067210411 (29)

11573/1266997 - 2019 - Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b
Pippa, S; Mannironi, C; Licursi, V; Bombardi, Luca; Colotti, G; Cundari, E; Mollica, A; Coluccia, A; Naccarato, V; La Regina, G; Silvestri, R; Negri, R - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000469518100098 (24) - scopus: 2-s2.0-85065652898 (25)

11573/1278549 - 2019 - Inhibition of human Norovirus replication by a novel class of oindolylarylsulfones in vitro and in zebrafish larvae
Van Dycke, Jana; Naccarato, Valentina; La Regina, Giuseppe; Mastrangelo, Eloise; Tarantino, Delia; Neyts, Johan; Silvestri, Romano; Rocha-Pereira, Joana - 04f Poster
conference: 32nd International Conference on Antiviral Research (Baltimora, Stati Uniti)
book: Program and Abstracts - ()

11573/1117672 - 2018 - Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects
Carnevale, Roberto; Silvestri, Romano; Loffredo, Lorenzo; Novo, Marta; Cammisotto, Vittoria; Castellani, Valentina; Bartimoccia, Simona; Nocella, Cristina; Violi, Francesco - 01a Articolo in rivista
paper: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (London: Macmillan Journals, 1974-) pp. 1566-1574 - issn: 0306-5251 - wos: WOS:000435440600019 (84) - scopus: 2-s2.0-85046287954 (90)

11573/1174760 - 2018 - Structure-based drug design of potent pyrazole derivatives against Rhinovirus replication
Da Costa, L.; Scheers, E.; Coluccia, A.; Casulli, A.; Roche, M.; Di Giorgio, C.; Neyts, J.; Terme, T.; Cirilli, R.; La Regina, G.; Silvestri, R.; Mirabelli, C.; Vanelle, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8402-8416 - issn: 0022-2623 - wos: WOS:000446142000022 (34) - scopus: 2-s2.0-85053181101 (38)

11573/954245 - 2018 - Bax activation blocks self-renewal and induces apoptosis of human glioblastoma stem cells
Daniele, S.; Pietrobono, D.; Costa, B.; Giustiniano, M.; La Pietra, V.; Giacomelli, C.; La Regina, Giuseppe; Silvestri, Romano; Taliani, S.; Trincavelli, M. L.; Da Settimo, F.; Novellino, E.; Martini, C.; Marinelli, L. - 01a Articolo in rivista
paper: ACS CHEMICAL NEUROSCIENCE (Washington, D.C. : American Chemical Society) pp. 85-99 - issn: 1948-7193 - wos: WOS:000423016300010 (22) - scopus: 2-s2.0-85040673427 (25)

11573/1072456 - 2018 - Indolylarylsulfones, a fascinating story of highly potent human immunodeficiency virus type 1 non-nucleoside reverse transcriptase inhibitors
Famiglini, V.; Silvestri, R. - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 1-19 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-85064224696 (16)

11573/1117718 - 2018 - New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors
La Regina, G.; Naccarato, V.; Coluccia, A.; Hamel, E.; Silvestri, R. - 04f Poster
conference: Seventh European Workshop in Drug Synthesis (Siena)
book: Seventh European Workshop in Drug Synthesis - ()

11573/1117651 - 2018 - New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors
La Regina, Giuseppe; Bai, Ruoli; Coluccia, Antonio; Naccarato, Valentina; Famiglini, Valeria; Nalli, Marianna; Masci, Domiziana; Verrico, Annalisa; Rovella, Paola; Mazzoccoli, Carmela; Da Pozzo, Eleonora; Cavallini, Chiara; Martini, Claudia; Vultaggio, Stefania; Dondio, Giulio; Varasi, Mario; Mercurio, Ciro; Hamel, Ernest; Lavia, Patrizia; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 283-297 - issn: 0223-5234 - wos: WOS:000435048900023 (31) - scopus: 2-s2.0-85046738606 (35)

11573/1170129 - 2018 - Treating chronic myeloid leukemia by inhibition of tubulin polymerization
La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Maria Luce Coluccia, Addolorata; Hamel, Ernest; Novellino, Ettore; Silvestri, Romano - 04b Atto di convegno in volume
conference: Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry (Palermo)
book: Book of Abstracts - ()

11573/1118125 - 2018 - Indolylarylsulfones with potent anti-HIV-1 activity
Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04f Poster
conference: 31st International Conference on Antiviral Research (Porto, Portogallo)
book: Program and Abstracts - ()

11573/1286679 - 2018 - Indolylarylsulfones as novel potent anti-HIV-1 agents
Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04d Abstract in atti di convegno
conference: 9th Biology and Molecular Medicine PhD School Symposium (BeMM) (Roma)
book: Book of Abstract - ()

11573/1019836 - 2018 - Arginine- and lysine-rich peptides: synthesis, characterization and antimicrobial activity
Mollica, A.; Macedonio, G.; Stefanucci, Azzurra; Costante, R.; Carradori, Simone; Cataldi, V.; Di Giulio, Anna Maria; Cellini, L.; Silvestri, Romano; Giordano, C.; Scipioni, Anita; Punzi, P.; Mirzaie, S. - 01a Articolo in rivista
paper: LETTERS IN DRUG DESIGN & DISCOVERY (Bentham Science Publishers Ltd) pp. 220-226 - issn: 1570-1808 - wos: WOS:000423791700002 (19) - scopus: 2-s2.0-85042152424 (24)

11573/1200815 - 2018 - A high-throughput screening of a chemical compound library in ovarian cancer stem cells
Ricci, F.; Carrassa, L.; Christodoulou, M. S.; Passarella, D.; Michel, B.; Benhida, R.; Martinet, N.; Hunyadi, A.; Ioannou, E.; Roussis, V.; Musso, L.; Dallavalle, S.; Silvestri, R.; Westwood, N.; Mori, M.; Ingallina, C.; Botta, B.; Kavetsou, E.; Detsi, A.; Majer, Z.; Hudecz, F.; Bősze, S.; Kaminska, B.; Hansen, T. V.; Bertrand, P.; Athanassopulos, C. M.; Damia, G. - 01a Articolo in rivista
paper: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 50-56 - issn: 1386-2073 - wos: WOS:000427836800007 (3) - scopus: 2-s2.0-85048467638 (4)

11573/1071883 - 2018 - A negative allosteric modulator of WNT receptor frizzled 4 switches into an allosteric agonist
Riccio, G.; Bottone, S.; La Regina, G.; Badolati, N.; Passacantilli, S.; Rossi, G. B.; Accardo, A.; Dentice, M.; Silvestri, R.; Novellino, E.; Stornaiuolo, M. - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 839-851 - issn: 0006-2960 - wos: WOS:000424723300047 (28) - scopus: 2-s2.0-85041457316 (27)

11573/1071891 - 2018 - β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy
Saponaro, Concetta; Sergio, Sara; Coluccia, Antonio; De Luca, Maria; La Regina, Giuseppe; Mologni, Luca; Famiglini, Valeria; Naccarato, Valentina; Bonetti, Daniela; Gautier, Candice Natacha Anna; Gianni, Stefano; Vergara, Daniele; Salzet, Michel; Fournier, Isabelle; Bucci, Cecilia; Silvestri, Romano; Gambacorti Passerini, Carlo; Maffia, Michele; Maria Luce Coluccia, Addolorata - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3301-3316 - issn: 0950-9232 - wos: WOS:000435526600009 (19) - scopus: 2-s2.0-85044095990 (22)

11573/1033464 - 2017 - Heterocyclic pharmacochemistry of new rhinovirus antiviral agents: a combined computational and experimental study
Da Costa, Laurene; Scheers, Els; Coluccia, Antonio; Rosetti, Alessia; Roche, Manon; Neyts, Johan; Terme, Thierry; Cirilli, Roberto; Mirabelli, Carmen; Silvestri, Romano; Vanelle, Patrice - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 528-541 - issn: 0223-5234 - wos: WOS:000414620000037 (11) - scopus: 2-s2.0-85030546760 (15)

11573/935705 - 2017 - Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules
Di Cesare, Erica; Verrico, Annalisa; Miele, Andrea; Giubettini, Maria; Rovella, Paola; Coluccia, Antonio; Famiglini, Valeria; La Regina, Giuseppe; Cundari, Enrico; Silvestri, Romano; Lavia, Patrizia - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 19738-19759 - issn: 1949-2553 - wos: WOS:000396879200088 (20) - scopus: 2-s2.0-85015806343 (21)

11573/1033459 - 2017 - New inhibitors of Dengue and Zika virus protease
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Lee, Jin-Ching; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()

11573/1014226 - 2017 - Chiral indolylarylsulfone non-nucleoside reverse transcriptase inhibitors as new potent and broad spectrum anti-HIV-1 agents
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Brancale, Andrea; Badia, Roger; Riveira Muã±Oz, Eva; Estã©, Josã© A.; Crespan, Emmanuele; Brambilla, Alessandro; Maga, Giovanni; Catalano, Myriam; Limatola, Cristina; Formica, Francesca Romana; Cirilli, Roberto; Novellino, Ettore; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6528-6547 - issn: 0022-2623 - wos: WOS:000407656700004 (20) - scopus: 2-s2.0-85027261384 (22)

11573/955375 - 2017 - N-​Pyrrylarylsulfones with high therapeutic potential
Famiglini, Valeria; Silvestri, Romano; Castellano, Sabrina - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000398743500095 (7) - scopus: 2-s2.0-85015716668 (8)

11573/1026343 - 2017 - Computer-aided identification and lead optimization of dual murine double minute 2 and 4 binders: structure-activity relationship studies and pharmacological activity
Giustiniano, M.; Daniele, S.; Pelliccia, S.; La Pietra, V.; Pietrobono, D.; Brancaccio, D.; Cosconati, S.; Messere, A.; Giuntini, S.; Cerofolini, L.; Fragai, M.; Luchinat, C.; Taliani, S.; La Regina, G.; Da Settimo, F.; Silvestri, R.; Martini, C.; Novellino, E.; Marinelli, L. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8115-8130 - issn: 0022-2623 - wos: WOS:000413131400012 (20) - scopus: 2-s2.0-85031292289 (20)

11573/954246 - 2017 - 3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin
La Regina, Giuseppe; Bai, R.; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Naccarato, Valentina; Ortar, Giorgio; Mazzoccoli, Carmela; Ruggieri, V.; Agriesti, F.; Piccoli, C.; Tataranni, T.; Nalli, Marianna; Brancale, A.; Vultaggio, S.; Mercurio, C.; Varasi, M.; Saponaro, C.; Sergio, S.; Maffia, M.; Coluccia, A. M. L.; Hamel, E.; Silvestri, Romano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 521-526 - issn: 1948-5875 - wos: WOS:000401402900010 (8) - scopus: 2-s2.0-85018898332 (9)

11573/1033450 - 2017 - Inhibition of Dengue virus by novel inhibitors of RNA-dependent RNA polymerase and protease activities
La Regina, Giuseppe; Famiglini, Valeria; Masci, Domiziana; Coluccia, Antonio; Lee, Jin-Ching; Hiscott, John; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()

11573/1033456 - 2017 - 3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin
La Regina, Giuseppe; Naccarato, Valentina; Coluccia, Antonio; Maria Luce Coluccia, Addolorata; Hamel, Ernest; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()

11573/1033458 - 2017 - Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors
Masci, Domiziana; La Regina, Giuseppe; Famiglini, Valeria; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()

11573/955362 - 2017 - Exploring the first Rimonabant analog-​opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors
Mollica, Adriano; Pelliccia, Sveva; Famiglini, Valeria; Stefanucci, Azzurra; Macedonio, Giorgia; Chiavaroli, Annalisa; Orlando, Giustino; Brunetti, Luigi; Ferrante, Claudio; Pieretti, Stefano; Novellino, Ettore; Benyhe, Sandor; Zador, Ferenc; Erdei, Anna; Szucs, Edina; Samavati, Reza; Dvrorasko, Szalbolch; Tomboly, Csaba; Ragno, Rino; Patsilinakos, Alexandros; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 444-451 - issn: 1475-6366 - wos: WOS:000392591100034 (33) - scopus: 2-s2.0-85015583368 (35)

11573/1033457 - 2017 - New pyrrole inhibitors of chronic myeloid leukemia cell growth
Naccarato, Valentina; La Regina, Giuseppe; Coluccia, Antonio; Maria Luce Coluccia, Addolorata; Hamel, Hernest; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()

11573/1033449 - 2017 - Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors
Passacantilli, Sara; Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Esté, José A.; Maga, Giovanni; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()

11573/1025425 - 2017 - Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities
Pelliccia, S.; Wub, Y. H.; Coluccia, A.; La Regina, G.; Tseng, C. K.; Famiglini, V.; Masci, D.; Hiscott, J.; Lee, J. C.; Silvestri, R. - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1091-1101 - issn: 1475-6366 - wos: WOS:000408991900004 (32) - scopus: 2-s2.0-85026861941 (33)

11573/902826 - 2017 - p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells
Soriani, Alessandra; Borrelli, Cristiana; Ricci, Biancamaria; Molfetta, Rosa; Zingoni, Alessandra; Fionda, Cinzia; Carnevale, Silvia; Abruzzese, Maria Pia; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; La Regina, Giuseppe; Cesare, Erica Di; Lavia, Patrizia; Silvestri, Romano; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. e1264564-e1264564 - issn: 2162-402X - wos: WOS:000397069400020 (32) - scopus: 2-s2.0-85015270684 (32)

11573/952050 - 2017 - Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells
Stirpe, Mariarita; Palermo, Vanessa; Bianchi, Michele Maria; Silvestri, Romano; Falcone, Claudio; Tenore, Giancarlo; Novellino, Ettore; Mazzoni, Cristina - 01a Articolo in rivista
paper: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (London: BioMed Central.) pp. - - issn: 1472-6882 - wos: WOS:000398770600001 (16) - scopus: 2-s2.0-85017244055 (20)

11573/907866 - 2016 - Structure-based virtual screening to get new scaffold inhibitors of the Ser/Thr protein kinase PknB from Mycobacterium tuberculosis
Coluccia, Antonio; La Regina, Giuseppe; Barilone, Nathalie; Lisa, María Natalia; Brancale, Andrea; André Leroux, Gwenaëlle; Alzari, Pedro M.; Silvestri, Romano - 01a Articolo in rivista
paper: LETTERS IN DRUG DESIGN & DISCOVERY (Bentham Science Publishers Ltd) pp. 1012-1018 - issn: 1570-1808 - wos: WOS:000389464700004 (5) - scopus: 2-s2.0-84995937420 (5)

11573/897502 - 2016 - New inhibitors of indoleamine 2,3-dioxygenase 1: molecular modeling studies, synthesis, and biological evaluation
Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Sabatino, Manuela; Patsilinakos, Alexandros; Ragno, Rino; Mazzoccoli, Carmela; Sisinni, L.; Okuno, A.; Takikawa, O.; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9760-9773 - issn: 0022-2623 - wos: WOS:000387737600010 (35) - scopus: 2-s2.0-84994853619 (37)

11573/872535 - 2016 - VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection
Da Costa, Laurène; Roche, Manon; Scheers, Els; Coluccia, Antonio; Neyts, Johan; Terme, Thierry; Leyssen, Pieter; Silvestri, Romano; Vanelle, Patrice - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 453-462 - issn: 0223-5234 - wos: WOS:000375360800039 (7) - scopus: 2-s2.0-84962663541 (9)

11573/887652 - 2016 - New Inhibitors of Dengue Virus Replication
Famiglini, Valeria; Pelliccia, Sveva; La Regina, Giuseppe; Coluccia, Antonio; Lee, J. C.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV National Meeting on Medicinal Chemistry (Perugia)
book: Abstract eBook - ()

11573/955391 - 2016 - Focus on chirality of HIV-​1 non-​nucleoside reverse transcriptase inhibitors
Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000371895900041 (21) - scopus: 2-s2.0-84964558153 (23)

11573/879604 - 2016 - Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(III) complex in human cancer cell lines
Filipović, N. R.; Bjelogrlić, S.; Portalone, G.; Pelliccia, S.; Silvestri, R.; Klisurić, O.; Senćanski, M.; Stanković, D.; Todorović, T. R.; Muller, Christian D. - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 1604-1616 - issn: 2040-2503 - wos: WOS:000381413300012 (16) - scopus: 2-s2.0-84982156083 (16)

11573/887653 - 2016 - New Inhibitors of indoleamine 2,3-dioxygenase 1: molecular modelling studies, synthesis and biological evaluation
La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Mazzoccoli, Carmela; Takikawa, O.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV National Meeting on Medicinal Chemistry (Perugia)
book: Abstract eBook - ()

11573/838741 - 2016 - Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo
Masuelli, Laura; Pantanella, Fabrizio; La Regina, Giuseppe; Benvenuto, Monica; Fantini, Massimo; Mattera, Rosanna; Di Stefano, Enrica; Mattei, Maurizio; Silvestri, Romano; Schippa, Serena; Manzari, Vittorio; Modesti, Andrea; Bei, Roberto - 01a Articolo in rivista
paper: TUMOR BIOLOGY (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 3705-3717 - issn: 1010-4283 - wos: WOS:000374903500096 (47) - scopus: 2-s2.0-84944704386 (52)

11573/880563 - 2016 - Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase
Pinto, Andrea; Tamborini, Lucia; Pennacchietti, Eugenia; Coluccia, Antonio; Silvestri, Romano; Cullia, Gregorio; De Micheli, Carlo; Conti, Paola; De Biase, Daniela - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 295-301 - issn: 1475-6366 - wos: WOS:000368719800014 (15) - scopus: 2-s2.0-84955443104 (15)

11573/1505230 - 2015 - New frontiers in selective human MAO-​B inhibitors
Carradori, S; Silvestri, R. - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6717-6732 - issn: 1520-4804 - wos: WOS:000361254600001 (194) - scopus: 2-s2.0-84937240385 (206)

11573/955459 - 2015 - Distinct temporal fingerprint for cyclic adenosine monophosphate (cAMP) signaling of Indole-​2-​carboxamides as allosteric modulators of the cannabinoid receptors
Cawston, Erin E.; Connor, Mark; Di Marzo, Vincenzo; Silvestri, Romano; Glass, Michelle - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5979-5988 - issn: 0022-2623 - wos: WOS:000359683700021 (25) - scopus: 2-s2.0-84939169250 (24)

11573/854568 - 2015 - Poster: "In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation”
Danovska, Svetlana; Cundari, Enrico; Mannironi, Cecilia; Licursi, Valerio; Rinaldi, Teresa; Fabozzi, Simone; Cerini, Valentina; Proietto, Marco; Pippa, Simone; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 04a Atto di comunicazione a congresso
conference: ICYGMB - Internationa Congress of Yeast Genetics and Molecular Biology (Levico Terme (TN))
book: Abstracts of the 27th International Conference on Yeast Genetics and Molecular Biology - ()

11573/868769 - 2015 - Drug Design and Synthesis of New Indolylarylsulfones as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Brancale, Andrea; Esté, José A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()

11573/764098 - 2015 - Pharmacological folding chaperones act as allosteric ligands of Frizzled4
Generoso, S. F; Giustiniano, M; La Regina, Giuseppe; Bottone, S; Passacantilli, Sara; Di Maro, S; Cassese, H; Bruno, A; Mallardo, M; Dentice, M; Silvestri, Romano; Marinelli, L; Sarnataro, D; Bonatti, S; Novellino, E; Stornaiuolo, M. - 01a Articolo in rivista
paper: NATURE CHEMICAL BIOLOGY (NATURE PUBLISHING GROUP, 75 VARICK STREET, 9TH FLOOR, NEW YORK, USA, NY, 10013-1917) pp. 280-286 - issn: 1552-4450 - wos: WOS:000351666500011 (44) - scopus: 2-s2.0-84930247167 (44)

11573/845844 - 2015 - New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer
La Regina, Giuseppe; Bai, Ruoli; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Mazzoccoli, Carmela; Ruggieri, Vitalba; Verrico, Annalisa; Miele, Andrea; Monti, Ludovica; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Ricci, Biancamaria; Soriani, Alessandra; Santoni, Angela; Caraglia, Michele; Porto, Stefania; Da Pozzo, Eleonora; Martini, Claudia; Brancale, Andrea; Marinelli, Luciana; Novellino, Ettore; Vultaggio, Stefania; Varasi, Mario; Mercurio, Ciro; Bigogno, Chiara; Dondio, Giulio; Hamel, Ernest; Lavia, Patrizia; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5789-5807 - issn: 0022-2623 - wos: WOS:000359683700008 (57) - scopus: 2-s2.0-84939138196 (57)

11573/845349 - 2015 - Discovery of 1,1'-biiphenyl-4-sulfonamides as a new class of potent and selective carbonic anhydrase XIV inhibitors
La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Monti, Ludovica; Vullo, Daniela; Nuti, Elisa; Alterio, Vincenzo; De Simone, Giuseppina; Monti, Simona Maria; Pan, Peiwen; Parkkila, Seppo; Supuran, Claudiu T.; Rossello, Armando; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8564-8572 - issn: 0022-2623 - wos: WOS:000364796100017 (36) - scopus: 2-s2.0-84947266183 (38)

11573/868746 - 2015 - New indole tubulin assembly inhibitors with stable arrest of mitotic progression, enhanced stimulation of natural killer cell cytotoxic activity and repression of Hedgehog-dependent cancer
La Regina, Giuseppe; Coluccia, Antonio; Hamel, Ernest; Novellino, Ettore; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Spanish-Italian Medicinal Chemistry Congress (Barcellona, Spagna)
book: SIMCC2015 - ()

11573/872560 - 2015 - In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses
Lacroix, Céline; Laconi, Samuela; Angius, Fabrizio; Coluccia, Antonio; Silvestri, Romano; Pompei, Raffaello; Neyts, Johan; Leyssen, Pieter - 01a Articolo in rivista
paper: VIROLOGY JOURNAL (London : Biomed Central) pp. - - issn: 1743-422X - wos: WOS:000357775400001 (26) - scopus: 2-s2.0-84937203434 (29)

11573/663213 - 2015 - New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2
Manvar, D.; Pelliccia, S.; La Regina, G.; Famiglini, V.; Coluccia, A.; Ruggieri, A.; Anticoli, S.; Lee, J. -C.; Basu, A.; Cevik, O.; Nencioni, L.; Palamara, A. T.; Zamperini, C.; Botta, M.; Neyts, J.; Leyssen, P.; Kaushik-Basu, N.; Silvestri, R. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 497-506 - issn: 0223-5234 - wos: WOS:000348951900040 (27) - scopus: 2-s2.0-84914680268 (31)

11573/868759 - 2015 - Synthesis of New Indoles with Potent Tubulin Polymerization Inhibiting Activity Including Hedgehog-Dependent Cancer and Enhanced Stimulation of NK Cell Cytotoxic Activity
Passacantilli, Sara; La Regina, Giuseppe; Coluccia, Antonio; Creta, Matteo; Hamel, Ernest; Novellino, Ettore; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()

11573/868767 - 2015 - New Pyrazolecarboxamides a s Anti-HCV Agents via Targeting Cyclooxygenase-2
Pelliccia, Sveva; La Regina, Giuseppe; Manvar, Dinesh; Kaushik Basu, Neerja; Neyts, Johan; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()

11573/955444 - 2015 - Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-​resistant Jurkat​/A4 cells
Philchenkov, Alex A.; Zavelevich, Michael P.; Tryndyak, Volodymyr P.; Kuiava, Ludmila M.; Blokhin, Dmitry Yu; Miura, Koh; Silvestri, Romano; Pogribny, Igor P. - 01a Articolo in rivista
paper: CANCER BIOLOGY & THERAPY (Georgetown, TX : Landes Bioscience) pp. 1820-1829 - issn: 1555-8576 - wos: WOS:000369916100016 (6) - scopus: 2-s2.0-84954526267 (7)

11573/780891 - 2015 - Kinetic characterization of 4,4'-biphenylsulfonamides as selective non-zinc binding MMP inhibitors
Santamaria, S; Nuti, E; Cercignani, G; La Regina, Giuseppe; Silvestri, Romano; Supuran C., T; Rossello, A. - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 947-954 - issn: 1475-6366 - wos: WOS:000369915500012 (14) - scopus: 2-s2.0-84945914800 (15)

11573/764095 - 2015 - Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents
Stornaiuolo, M.; La Regina, Giuseppe; Passacantilli, Sara; Grassia, G.; Coluccia, Antonio; La Pietra, V.; Giustiniano, M.; Cassese, H.; Di Maro, S.; Brancaccio, D.; Taliani, S.; Ialenti, A.; Silvestri, Romano; Martini, C.; Novellino, E.; Marinelli, L. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2135-2148 - issn: 0022-2623 - wos: WOS:000351186500007 (36) - scopus: 2-s2.0-84924664711 (37)

11573/845838 - 2015 - Endogenous vs exogenous allosteric modulators in GPCRs: a dispute for shuttling CB1 among different membrane microenvironments
Stornaiuolo, Mariano; Bruno, Agostino; Botta, Lorenzo; La Regina, Giuseppe; Cosconati, Sandro; Silvestri, Romano; Marinelli, Luciana; Novellino, Ettore - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London: Springer Nature London: Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000363036200001 (35) - scopus: 2-s2.0-84945193701 (38)

11573/538415 - 2014 - An High-Throughput In Vivo Screening System to Select H3K4-Specific Histone Demethylase Inhibitors
Cecilia, Mannironi; Proietto, Marco; Bufalieri, Francesca; Enrico, Cundari; Alagia, Angela Alessandra; Danovska, Svetlana; Rinaldi, Teresa; Famiglini, Valeria; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e86002-e86002 - issn: 1932-6203 - wos: WOS:000330570000022 (15) - scopus: 2-s2.0-84900435770 (16)

11573/675447 - 2014 - New modulator of the tumoural immune escape via Indoleamin 2,3-dioxygenase (IDO) inhibition.
Coluccia, Antonio; La Regina, Giuseppe; Okuno, A.; Takikawa, O.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXV Congresso Nazionale della Società Chimica Italiana (Arcavacata di Rende)
book: Atti del Congresso - ()

11573/675493 - 2014 - New Indolylarylsulfones as Potent and Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors.
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Brancale, A.; Esté, J. A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: International Conference on Antiviral Research (Raleigh, USA)
book: Program and Abstracts - ()

11573/675451 - 2014 - New Indolylarylsulfones as Potent and Broad Spectrum HIV‐1 Non-Nucleoside Reverse Transcriptase Inhibitors. II.
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Brancale, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()

11573/671843 - 2014 - Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Pelliccia, S.; Brancale, A.; Maga, G.; Crespan, E.; Badia, R.; Riveira Munoz, E.; Este, J. A.; Ferretti, R.; Cirilli, R.; Zamperini, C.; Botta, M.; Schols, D.; Limongelli, V.; Agostino, B.; Novellino, E.; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9945-9957 - issn: 0022-2623 - wos: WOS:000346321200017 (44) - scopus: 2-s2.0-84918566396 (49)

11573/559735 - 2014 - New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Pelliccia, S; Brancale, A; Maga, G; Crespan, E; Badia, R; Clotet, B; Este J., A; Cirilli, R; Novellino, E; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 101-111 - issn: 0223-5234 - wos: WOS:000337985400009 (22) - scopus: 2-s2.0-84899103627 (24)

11573/649699 - 2014 - New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer
La Regina, Giuseppe; Bai, R; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Mazzoccoli, C; Ruggieri, V; Sisinni, L; Bolognesi, A; Rensen, W. M.; Miele, Andrea; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Brancale, A; Novellino, E; Dondio, G; Vultaggio, S; Varasi, M; Mercurio, C; Hamel, E; Lavia, P; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6531-6552 - issn: 0022-2623 - wos: WOS:000340445900020 (80) - scopus: 2-s2.0-84906094556 (86)

11573/675361 - 2014 - 3-Aroyl-1-arylpyrroles as new anticancer agents
La Regina, Giuseppe; Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Pelliccia, S.; Hamel, E.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXV Congresso Nazionale della Società Chimica Italiana (Arcavacata di Rende (CS))
book: Atti del Congresso - ()

11573/675406 - 2014 - 3-Aroyl-1-arylpyrroles: a new class of potent inhibitors of tubulin polymerization
La Regina, Giuseppe; Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Pelliccia, Sveva; Hamel, E.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Fifth European Workshop in Drug Synthesis (Siena (SI))
book: Fifth European Workshop in Drug Synthesis - ()

11573/558611 - 2014 - New, simple and high-yielding synthesis of 2,9-dihydro-1H-pyrido[3,4-b]indol-1-ones
La Regina, Giuseppe; Famiglini, Valeria; Passacantilli, Sara; Pelliccia, S; Punzi, P; Silvestri, Romano - 01a Articolo in rivista
paper: SYNTHESIS (Stuttgart : Thieme Verlag) pp. 2093-2097 - issn: 0039-7881 - wos: WOS:000340874800016 (7) - scopus: 2-s2.0-84904763883 (10)

11573/671846 - 2014 - Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors
Marzaro, G.; Coluccia, Antonio; Ferrarese, A.; Brun, P.; Castagliuolo, I.; Conconi, M. T.; La Regina, Giuseppe; Bai, R.; Silvestri, Romano; Hamel, E.; Chilin, A. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4598-4605 - issn: 0022-2623 - wos: WOS:000337336600014 (30) - scopus: 2-s2.0-84902438483 (28)

11573/675453 - 2014 - Selective Synthesis of 2,9-Dihydro-1H-Pyrido[3,4-b]indol-1-ones.
Passacantilli, Sara; Pelliccia, S.; La Regina, Giuseppe; Famiglini, Valeria; Punzi, P.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()

11573/675489 - 2014 - New 1-Phenyl‐5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides Inhibit Hepatitis C Virus Replication and Suppress the Expression of Cyclooxygenase-2.
Pelliccia, S.; La Regina, Giuseppe; Manvar, D.; Kaushik Basu, N.; Neyts, J.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()

11573/675496 - 2014 - New 1-Phenyl-5-(1H-Pyrrol-1-Yl)-1H-Pyrazole-3-Carboxamides Inhibit Hepatitis C Virus Replication and Suppress the Expression of Cyclooxygenase-2.
Pelliccia, S.; Manvar, D.; La Regina, Giuseppe; Neyts, J.; Kaushik Basu, N.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 27th International Conference on Antiviral Research (Raleigh, USA)
book: Program and Abstracts - ()

11573/555507 - 2013 - Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus.
Bassetto, M.; De Burghgraeveb, T.; Delangb, L.; Massarotti, A.; Zonta, N.; Gatti, Valerio; Colombano, G.; Sorba, G.; Silvestri, Romano; Tron, G. C.; Neyts, J.; Leyssen, P.; Brancale, A.; Coluccia, Antonio - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH ([Amsterdam]; [New York]: Elsevier/North-Holland, [c1981]-) pp. 12-18 - issn: 0166-3542 - wos: WOS:000318466200003 (86) - scopus: 2-s2.0-84874632357 (96)

11573/555510 - 2013 - Exploring (4-substituted-thiazol-2-yl)hydrazine derivatives of 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors.
Chimenti, Paola; Petzer, A.; Carradori, S.; D’Ascenzio, M.; Silvestri, Romano; Alcaro, S.; Ortuso, F.; Petzer, J. J.; Secci, Daniela - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 221-227 - issn: 0223-5234 - wos: WOS:000323628500024 (27) - scopus: 2-s2.0-84879467536 (26)

11573/675503 - 2013 - Computational studies of colchicine site compounds.
Coluccia, Antonio; La Regina, Giuseppe; Brancale, A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()

11573/547290 - 2013 - Drug design and synthesis of GSK-3β inhibitors.
Famiglini, Valeria; Bordoni, C.; La Pietra, V.; La Regina, Giuseppe; Coluccia, Antonio; Pelliccia, S.; Plotkin, B.; Eldar Finkelman, H.; Brancale, A.; Marinelli, L.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()

11573/546082 - 2013 - Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors
Famiglini, Valeria; Coluccia, Antonio; Andrea, Brancale; Sveva, Pelliccia; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2141-2156 - issn: 1756-8919 - wos: WOS:000327222400008 (17) - scopus: 2-s2.0-84889578221 (18)

11573/547288 - 2013 - New indolylarylsulfones as potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Brancale, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()

11573/509896 - 2013 - Toward Highly Potent Cancer Agents by Modulating the C-2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors
La Regina, Giuseppe; Ruoli, Bai; Whilelmina Maria, Rensen; Di Cesare, Erica; Coluccia, Antonio; Piscitelli, Francesco; Famiglini, Valeria; Alessia, Reggio; Nalli, Marianna; Pelliccia, Sveva; Eleonora Da, Pozzo; Barbara, Costa; Ilaria, Granata; Amalia, Porta; Bruno, Maresca; Soriani, Alessandra; Iannitto, Maria Luisa; Santoni, Angela; Junjie, Li; M. M., Cona; Feng, Chen; Yicheng, Ni; Andrea, Brancale; Giulio, Dondio; Stefania, Vultaggio; Mario, Varasi; Ciro, Mercurio; Claudia, Martini; Ernest, Hamel; Patrizia, Lavia; Ettore, Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 123-149 - issn: 0022-2623 - wos: WOS:000313221600012 (120) - scopus: 2-s2.0-84872352365 (121)

11573/547286 - 2013 - Highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
Pelliccia, S.; La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Nalli, M.; Brancale, A.; Hamel, E.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()

11573/547287 - 2013 - A new, simple and high yielding synthesis of 2,9-dihydro-1H-pyrido[3,4-b]indol-1-ones.
Pelliccia, S.; La Regina, Giuseppe; Famiglini, Valeria; Punzi, P.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()

11573/771841 - 2013 - D,L peptides as strong inhibitors of HIV-1 GP120.
Punzi, Pasqualina; C., Giordano; Morosetti, Stefano; P., De Santis; Silvestri, Romano; Scipioni, Anita - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry NMMC 2013 (Roma)
book: XXII National Meeting on Medicinal Chemistry NMMC 2013 - ()

11573/555492 - 2013 - New prospects for vinblastine analogues as anticancer agents.
Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 625-627 - issn: 0022-2623 - wos: WOS:000315182100002 (47) - scopus: 2-s2.0-84873886062 (50)

11573/541254 - 2013 - Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors
V., La Pietra; La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; S., Pelliccia; B., Plotkin; H., Eldar Finkelman; A., Brancale; C., Ballatore; A., Crowe; Kr, Brunden; L., Marinelli; E., Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10066-10078 - issn: 0022-2623 - wos: WOS:000329331600018 (36) - scopus: 2-s2.0-84891341466 (43)

11573/482220 - 2012 - A new allosteric inhibitor of the hepatitis C virus NS5B polymerase is effective on HCV replication in infected cell culture system.
A., Ruggieri; Anticoli, Simona; Piscitelli, Francesco; Silvestri, Romano; Nencioni, Lucia; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
conference: 11th NATIONAL CONGRESS OF THE ITALIAN SOCIETY FOR VIROLOGY (ORVIETO (TR)
, Italy)

11573/501681 - 2012 - Computer aided drug design approach in the development of PKnB inhibitors as potential antimycobacterial agents.
Coluccia, Antonio; La Regina, Giuseppe; Piscitelli, Francesco; E., Novellino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Meeting Nuove Prospettive in Chimica Farmaceutica 6 (Riccione)
book: Abstracts - ()

11573/501381 - 2012 - New Indolylarylsulfones as Potent and Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; A., Brancale; E., Novellino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 12° Sigma Aldrich Young Chemists Symposium (Riccione)
book: Abstracts - ()

11573/501679 - 2012 - First venting while heating microwave-assisted synthesis of 3-arylthioindoles as potent Inhibitors of tubulin polymerization.
Famiglini, Valeria; La Regina, Giuseppe; E., Novellino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Meeting Nuove Prospettive in Chimica Farmaceutica 6 (Riccione)
book: Abstracts - ()

11573/461861 - 2012 - New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
La Regina, Giuseppe; Coluccia, Antonio; Andrea, Brancale; Piscitelli, Francesco; Famiglini, Valeria; Sandro, Cosconati; Giovanni, Maga; Alberta, Samuele; E., Gonzales; Bonaventura, Clotet; Dominique, Schols; Jose A., Este; Ettore, Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6634-6638 - issn: 0022-2623 - wos: WOS:000306764600035 (52) - scopus: 2-s2.0-84864247649 (64)

11573/502189 - 2012 - Venting-while-heating microwave-assisted synthesis of 3-arylthioindoles
La Regina, Giuseppe; Gatti, Valerio; Famiglini, Valeria; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: ACS COMBINATORIAL SCIENCE (Washington, DC : American Chemical Society) pp. 258-262 - issn: 2156-8952 - wos: WOS:000303076400003 (39) - scopus: 2-s2.0-84859727783 (57)

11573/681651 - 2012 - The tubulin colchicine domain: a molecular modelling perspective.
Massarotti, A.; Coluccia, Antonio; Silvestri, Romano; Brancale, A. - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 33-42 - issn: 1860-7179 - wos: WOS:000298549100003 (141) - scopus: 2-s2.0-84555195099 (145)

11573/555514 - 2012 - De novo computer-aided design of novel antiviral agents.
Massarotti, A.; Coluccia, Antonio; Sorba, G.; Silvestri, Romano; Brancale, A. - 01a Articolo in rivista
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 213-218 - issn: 1359-6446 - wos: (0) - scopus: 2-s2.0-84873076621 (2)

11573/483800 - 2012 - Apple Can Act as Anti-Aging on Yeast Cells
Palermo, Vanessa; Fulvio, Mattivi; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 01a Articolo in rivista
paper: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. 1-8 - issn: 1942-0900 - wos: WOS:000308498000001 (26) - scopus: 2-s2.0-84867365062 (26)

11573/502138 - 2012 - Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid CB1 Receptor
Piscitelli, Francesco; A., Ligresti; La Regina, Giuseppe; Coluccia, Antonio; L., Morera; M., Allara; E., Novellino; V., Di Marzo; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5627-5631 - issn: 0022-2623 - wos: WOS:000305356400058 (56) - scopus: 2-s2.0-84862272370 (58)

11573/501390 - 2012 - New 2-Heterocyclil-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors
S., Pelliccia; La Regina, Giuseppe; Coluccia, Antonio; A., Brancale; E., Novellino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 12° Sigma Aldrich Young Chemists Symposium (Riccione)
book: Abstracts - ()

11573/502211 - 2011 - Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates
A., Samuele; S., Bisi; A., Kataropoulou; La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Silvestri, Romano; G., Maga - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 107-118 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-84861534913 (8)

11573/396005 - 2011 - Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. New Cyclic Substituents at the Indole-2-carboxamide.
Coluccia, Antonio; La Regina, Giuseppe; Gatti, Valerio; Piscitelli, Francesco; Famiglini, V.; Brancale, A.; Maga, G.; Balzarini, J.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV Congresso Nazionale della Società Chimica Italiana (Lecce)
book: Atti del Congresso - ()

11573/1026412 - 2011 - Open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-aryl hydrazones
La Regina, G.; Gatti, V.; Piscitelli, F.; Silvestri, R. - 01a Articolo in rivista
paper: ACS COMBINATORIAL SCIENCE (Washington, DC : American Chemical Society) pp. 2-6 - issn: 2156-8952 - wos: WOS:000288062600001 (22) - scopus: 2-s2.0-78651432876 (24)

11573/355392 - 2011 - Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors. New cyclic substituents at the Indole-2-carboxamide
La Regina, Giuseppe; Coluccia, Antonio; A., Brancale; G., Maga; J., Balzarini; E., Novellino; Silvestri, Romano - 04d Abstract in atti di convegno
conference: The 24th International Meeting on Antiviral Research (Sofia; Bulgaria)
book: Abstracts - ()

11573/502235 - 2011 - Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: New Cyclic Substituents at the Indole-2-carboxamide.
La Regina, Giuseppe; Coluccia, Antonio; A., Brancale; Piscitelli, Francesco; Gatti, Valerio; G., Maga; A., Samuele; C., Pannecouque; D., Schols; J., Balzarini; E., Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1587-1598 - issn: 0022-2623 - wos: WOS:000288400700005 (132) - scopus: 2-s2.0-79952792724 (161)

11573/502225 - 2011 - Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability
La Regina, Giuseppe; Ruoli, Bai; Willeke, Rensen; Coluccia, Antonio; Piscitelli, Francesco; Gatti, Valerio; Alessio, Bolognesi; Antonio, Lavecchia; Ilaria, Granata; Amalia, Porta; Bruno, Maresca; Soriani, Alessandra; Iannitto, Maria Luisa; Marisa, Mariani; Santoni, Angela; Andrea, Brancale; Cristiano, Ferlini; Giulio, Dondio; Mario, Varasi; Ciro, Mercurio; Ernest, Hamel; Patrizia, Lavia; Ettore, Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8394-8406 - issn: 0022-2623 - wos: WOS:000297946300016 (76) - scopus: 2-s2.0-84055211830 (80)

11573/502195 - 2011 - Drug-induced inhibition of tubulin polymerization induces mitochondrion-mediated apoptosis in yeast
Palermo, Vanessa; Luisa, Pieri; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3208-3209 - issn: 1538-4101 - wos: WOS:000294954400034 (8) - scopus: 2-s2.0-80052908186 (8)

11573/395350 - 2011 - 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands.
Piscitelli, Francesco; Ligresti, A.; La Regina, Giuseppe; Gatti, Valerio; Brizzi, A.; Pasquini, S.; Allarà, M.; Carai, M. A. M.; Novellino, E.; Colombo, G.; Di Marzo, V.; Corelli, F.; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 5641-5653 - issn: 0223-5234 - wos: WOS:000298120500043 (19) - scopus: 2-s2.0-80054960004 (20)

11573/396013 - 2011 - 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands.
Piscitelli, Francesco; Ligresti, A.; La Regina, Giuseppe; Gatti, Valerio; Brizzi, A.; Pasquini, S.; Allara’, M.; Carai, M. A. M.; Novellino, E.; Colombo, G.; Di Marzo, V.; Corelli, F.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV Congresso Nazionale della Società Chimica Italiana (Lecce)
book: Atti del Congresso - ()

11573/71630 - 2010 - Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs) exert their anti-proliferative activity by interfering with Akt-mTOR signaling and bax:bcl-2 ratio modulation in cells from chronic myeloid leukemic patients
Carla Di, Stefano; Gabriella, Marfe; Malgorzata Monika, Trawinska; Paola Sinibaldi, Salimei; Silvestri, Romano; Sergio, Amadori; Elisabetta, Abruzzese - 01a Articolo in rivista
paper: CANCER SCIENCE (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 991-1000 - issn: 1347-9032 - wos: WOS:000275728200024 (7) - scopus: 2-s2.0-77957282697 (7)

11573/355390 - 2010 - Molecular dynamic studies of arylthioindoles, potent inhibitors of tubulin polymerization
Coluccia, A; Brancale, A; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX national Meeting on Medicinal Chemistry (Abano Terme, Padova)
book: Book of Abstracts - ()

11573/355731 - 2010 - Discovery of a novel hcv helicase inhibitors by a de novo design approach.
Coluccia, A; Leyssen, P; Neyts, J; Kandil, S; Brancale, A; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX national Meeting on Medicinal Chemistry (Abano Terme, Padova)
book: Book of Abtracts - ()

11573/355391 - 2010 - Indolylarylsulfones bearing natural and unnatural amino acids as inhibitors of HIV-1 reverse transcriptase and Coxsackie B4 virus.
Gatti, Valerio; La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; C., Giordano; A., Brancale; J., Balzarini; G., Maga; E., Novellino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Antiviral Congress (Amsterdam (NL))
book: Abstracts - ()

11573/226813 - 2010 - Synthesis, in vivo pharmacological evaluation and pharmacokinetic studies of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide cannabinoid receptor ligands.
Gatti, Valerio; La Regina, Giuseppe; Piscitelli, Francesco; Colombo, G.; Di Marzo, V.; Corelli, F.; Novellino, E.; La Vecchia, A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica, IV Meeting – Workshop (Santa Margherita di Pula (CA))
book: Abstracts - ()

11573/502271 - 2010 - Arylthioindoles: Promising compounds against cancer cell proliferation.
Giansanti, V.; Piscitelli, Francesco; Camboni, T.; Prosperi, E.; La Regina, Giuseppe; Parks, M.; Silvestri, Romano; Scovassi, A. I. - 01a Articolo in rivista
paper: ONCOLOGY LETTERS (Athens Greece: Spandidos Publications Ltd.) pp. 109-112 - issn: 1792-1074 - wos: WOS:000284562300020 (9) - scopus: 2-s2.0-77955753209 (9)

11573/366769 - 2010 - Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors
La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 213-237 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-77956900680 (66)

11573/396161 - 2010 - New N-Alkyl 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as potent cannabinoid receptor ligands.
La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Colombo, G.; Di Marzo, V.; Corelli, F.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX National Meetings on Medicinal Chemistry (Abano Terme - Padova)
book: Book of Abstracts - ()

11573/412070 - 2010 - S. cerevisiae as a model for the study of new therapeutic molecules
Palermo, Vanessa; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 04c Atto di convegno in rivista
paper: JOURNAL OF BIOTECHNOLOGY (Amsterdam Netherlands: Elsevier BV) pp. 412-412 - issn: 0168-1656 - wos: WOS:000288873401735 (0) - scopus: (0)
conference: 14th International Biotechnology Symposium and Exhibition (Rimini Italy)

11573/362016 - 2010 - Enantioselective HPLC combined with spectroscopic methods: A valid strategy to determine the absolute configuration of potential beta-secretase inhibitors
R., Cirilli; R., Ferretti; La Regina, Giuseppe; G., Morelli; Pierini, Marco; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: TALANTA (-Oxford, United Kingdom: Elsevier Science Limited Oxford: Pergamon, 1958-) pp. 1306-1312 - issn: 0039-9140 - wos: WOS:000282480500032 (12) - scopus: 2-s2.0-77956182621 (12)

11573/71306 - 2010 - A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds
Screpanti, E; Santaguida, S; Mguyen, T; Silvestri, Romano; Gussio, R; Musacchio, A; Hamel, E; De Wulf, P. - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. 1-13 - issn: 1932-6203 - wos: WOS:000279924500007 (16) - scopus: 2-s2.0-77955407826 (19)

11573/362000 - 2010 - Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands.
Silvestri, Romano; Ligresti, A.; La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Lavecchia, A.; Brizzi, A.; Pasquini, S.; Allarà, M.; Fantini, N.; Carai, M. A. M.; Bigogno, C.; Rozio, M. G.; Sinisi, R.; Novellino, E.; Colombo, E.; Di Marzo, V.; Dondio, G.; Corelli, F. - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 5878-5886 - issn: 0223-5234 - wos: WOS:000285485000040 (10) - scopus: 2-s2.0-78649319952 (10)

11573/227389 - 2010 - Radiosynthesis and in vivo evaluation of [11C]-labelled pyrrole-2-carboxamide derivates as novel radioligands for PET imaging of monoamine oxidase A
Sylvie De, Bruyne; La Regina, Giuseppe; S., Staelensc; Leonie, Wyffels; Steven, Deleye; Silvestri, Romano; Filip De, Vos - 01a Articolo in rivista
paper: NUCLEAR MEDICINE AND BIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 459-467 - issn: 0969-8051 - wos: WOS:000277701900010 (10) - scopus: 2-s2.0-77952549176 (13)

11573/225640 - 2009 - Molecular Modeling applications studies on the Indolyl Aryl Sulphones (IASs) as HIV-1 Non-Nucleotidic Reverse transcriptase inhibitors.
Coluccia, Antonio; Brancale, A.; La Regina, Giuseppe; Lavecchia, A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()

11573/225842 - 2009 - Drug Design of New NS3/4A HCV Serine Protease Inhibitors. Structure-Based and Ligand-Based Approaches.
Coluccia, Antonio; La Regina, Giuseppe; Giordano, C.; Sansone, A.; Brancale, A.; Neyts, J.; Leyssen, P.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()

11573/396023 - 2009 - Radiosynthesis and in vivo evaluation of [11C]-(R)-N-(1-cyclohexylethyl-N-methyl-1H-pyrrole-2-carboxamide.
De Bruyne, S.; Wyffels, L.; Moerman, L.; La Regina, Giuseppe; Silvestri, Romano; De Vos, F. - 04a Atto di comunicazione a congresso
conference: 18th International Symposium on Radiopharmaceutical Sciences (Edmonton, Canada)
book: Abstracts of Presentations - ()

11573/226395 - 2009 - Arylthioindole Bioisosteres as Potent Tubulin Polymerization and MCF-7 Cell Growth Inhibitors
Gatti, Valerio; La Regina, Giuseppe; Coluccia, Antonio; Brancale, A.; Hamel, E.; Scovassi, A.; Maresca, B.; Campiglia, P.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()

11573/226692 - 2009 - Polymerization and MCF-7 Cell Growth Inhibitors. New Bioisosteres at the Sulfur Bridging Group.
Gatti, Valerio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()

11573/225846 - 2009 - Design and synthesis of novel metalloproteinases inhibitors
Kieres, K.; Sala, M.; Campiglia, P.; Musella, S.; Giustiniano, M.; Nuti, E.; La Regina, Giuseppe; Silvestri, Romano; Gomez Monterrey, I.; Novellino, E.; Rossello, A. - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()

11573/226478 - 2009 - Molecular Modeling Studies of Arylthioindoles and Related Bioisosteres, Potent Inhibitors of Tubulin Polymerization.
La Regina, Giuseppe; Coluccia, Antonio; Gatti, Valerio; Saletti, R.; Brancale, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: VI European Workshop in Drug Design (Certosa di Pontignano)
book: Abstracts - ()

11573/226397 - 2009 - New Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as High Affinity hCB1 Ligands
La Regina, Giuseppe; Piscitelli, Francesco; Ligresti, A.; Brizzi, A.; Pasquini, S.; Colombo, G.; Lavecchia, A.; Corelli, F.; Di Marzo, V.; Novellino, R.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()

11573/502676 - 2009 - Synthetic Strategies of Non-Peptidic beta-Secretase (BACE1) Inhibitors.
La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 10-17 - issn: 0022-152X - wos: WOS:000264349600002 (6) - scopus: 2-s2.0-61849126868 (9)

11573/358688 - 2009 - New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies
La Regina, Giuseppe; Taradas, Sarkar; Ruoli, Bai; Michael C., Edler; Roberto, Saletti; Coluccia, Antonio; Piscitelli, Francesco; Lara, Minelli; Gatti, Valerio; Carmela, Mazzoccoli; Palermo, Vanessa; Mazzoni, Cristina; Falcone, Claudio; Anna Ivana, Scovassi; Vincenzo, Giansanti; Pietro, Campiglia; Amalia, Porta; Bruno, Maresca; Ernest, Hamel; Andrea, Brancale; Ettore, Novellino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 7512-7527 - issn: 0022-2623 - wos: WOS:000272338000020 (95) - scopus: 2-s2.0-72249084715 (101)

11573/226394 - 2009 - Indolylarylsulfones Bearing Natural and Unnatural Amino Acids are Potent HIV-1 Reverse Transcriptase and Coxsackie B4 Virus Non-Nucleoside Inhibitors.
Piscitelli, Francesco; Coluccia, Antonio; Brancale, A.; La Regina, Giuseppe; Sansone, A.; Giordano, C.; Balzarini, J.; Maga, G.; Zanoli, S.; Samuele, A.; Cirilli, R.; La Torre, F.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: The 22nd International Meeting on Antiviral Research (Miami Beach, Florida, USA)
book: Abstracts - ()

11573/364587 - 2009 - Indolyl Aryl Sulfones bearing Natural and Unnatural Aminoacids. Discovery of Potent Inhibitors of both HIV-1 Non-Nucleoside Wild Type and Resistant Mutant Strains Reverse Transcriptase, and Coxsackie B4 Virus.
Piscitelli, Francesco; Coluccia, Antonio; Brancale, A.; La Regina, Giuseppe; Sansone, A.; Giordano, C.; Balzarini, J.; Maga, G.; Zanoli, S.; Samuele, A.; Cirilli, R.; La Torre, F.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1922-1934 - issn: 0022-2623 - wos: WOS:000264835800014 (59) - scopus: 2-s2.0-64549155260 (62)

11573/225843 - 2009 - Indolylarylsulfones Bearing Natural and Unnatural Amino Acids as Potent HIV-1 NNRTIs.
Piscitelli, Francesco; La Regina, Giuseppe; Gatti, Valerio; Coluccia, Antonio; Brancale, A.; Giordano, C.; Balzarini, J.; Maga, G.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()

11573/362045 - 2009 - Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex.
Samuele, A.; Kataropoulou, A.; Viola, M.; Zanoli, S.; La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano; Maga, G. - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH ([Amsterdam]; [New York]: Elsevier/North-Holland, [c1981]-) pp. 47-55 - issn: 0166-3542 - wos: WOS:000262589900006 (16) - scopus: 2-s2.0-57149112301 (17)

11573/71628 - 2009 - Boom in the development of non-peptidic beta-secretase (BACE1) inhibitors for the treatment of Alzheimer's disease
Silvestri, Romano - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 295-338 - issn: 0198-6325 - wos: WOS:000263510600003 (108) - scopus: 2-s2.0-62249167406 (115)

11573/359833 - 2009 - Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile
Silvestri, Romano; Alessia, Ligresti; La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Antonella, Brizzi; Serena, Pasquini; Antonio, Lavecchia; Marco, Allara; Noemi, Fantini; Mauro Antonio Maria, Carai; Ettore, Novellino; Giancarlo, Colombo; V., Di Marzo; C., Corelli - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 5549-5564 - issn: 0968-0896 - wos: WOS:000268099700023 (18) - scopus: 2-s2.0-67849084545 (17)

11573/501687 - 2009 - Pirazolocarbossiamidi e morte cellulare: una nuova arma per la chemioterapia.
V., Giansanti; T., Camboni; M., Tillhon; M., Parks; E., Prosperi; G. Santin, G.; Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano; A. Scovassi, A. - 04a Atto di comunicazione a congresso
conference: La morte della cellula: implicazioni fisio-patologiche e terapeutiche (Firenze)
book: Atti - ()

11573/364409 - 2009 - Study of the effects of a new pyrazolecarboxamide: Changes in mitochondria and induction of apoptosis
Vincenzo, Giansanti; Tania, Camboni; Piscitelli, Francesco; Ennio, Prosperi; La Regina, Giuseppe; Maria C., Lazze; Giada, Santin; Silvestri, Romano; Anna I., Scovassi - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1890-1898 - issn: 1357-2725 - wos: WOS:000270351100016 (16) - scopus: 2-s2.0-68949092046 (19)

11573/364131 - 2008 - 1-[(3-Aryloxy-3-aryl)propyl]-2H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies
La Regina, Giuseppe; D'auria, Felicia Diodata; Tafi, A; Piscitelli, Francesco; Olla, S; Caporuscio, F; Nencioni, Lucia; Cirilli, R; La Torre, R; De Melo N., R; Kelly S., L; Lamb D., C; Artico, Marino; Botta, M; Palamara, Anna Teresa; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3841-3855 - issn: 0022-2623 - wos: WOS:000257391000019 (32) - scopus: 2-s2.0-46849105237 (33)

11573/224410 - 2008 - Progress in the development of arylthioindoles, potent inhibitors of tubulin polymerization and MCF-7 cell growth.
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Brancale, A.; Hamel, E.; Diaz, J. F.; Scovassi, A. I.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XIX National Meeting on Medicinal Chemistry (Verona, Italy)
book: Book of Abstracts - ()

11573/396351 - 2008 - Progress in the development of arylthioindoles, potent inhibitors of tubulin polymerization and MCF-7 cell growth.
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Brancale, A.; Hamel, E.; Diaz, J. F.; Scovassi, A. I.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()

11573/224408 - 2008 - Docking and Molecular Dynamics Studies of Arylthioindoles.
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Minelli, L.; Brancale, A.; Kandil, S.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XIX National Meeting on Medicinal Chemistry (Verona, Italy)
book: Book of Abstracts - ()

11573/396552 - 2008 - Docking and Molecular Dynamics Studies of Arylthioindoles.
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Minelli, L.; Brancale, A.; Kandil, S.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()

11573/364212 - 2008 - Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B.
La Regina, Giuseppe; Silvestri, Romano; Gatti, Valerio; Lavecchia, A.; Novellino, E.; Befani, O.; Turini, P.; Agostinelli, Enzo - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 9729-9740 - issn: 0968-0896 - wos: WOS:000260758200011 (38) - scopus: (0)

11573/396610 - 2008 - Indolyl Aryl Sulfones with aminoacid units as potent HIV-1 NNRTIs.
Piscitelli, Francesco; La Regina, Giuseppe; Coluccia, Antonio; Sansone, A.; Giordano, C.; Bergamini, A.; Sinistro, A.; Cavazza, A.; Maga, G.; Samuele, A.; Zanoli, S.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()

11573/364205 - 2008 - An improved synthesis of ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 204-208 - issn: 0030-4948 - wos: WOS:000255310900004 (4) - scopus: 2-s2.0-44149117529 (5)

11573/362035 - 2008 - Synthesis, Cannabinoid Receptor Affinity and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.
Silvestri, Romano; Cascio, M. G.; La Regina, Giuseppe; Piscitelli, Francesco; Lavecchia, A.; Brizzi, A.; Pasquini, S.; Botta, M.; Novellino, E.; Di Marzo, V.; Corelli, F. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1560-1576 - issn: 0022-2623 - wos: WOS:000254209800005 (69) - scopus: 2-s2.0-41149151354 (73)

11573/72148 - 2007 - Indole, a Core Nucleus for Potent Inhibitors of Tubulin Polymerization.
Brancale, A; Silvestri, Romano - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 209-238 - issn: 0198-6325 - wos: WOS:000244254500003 (347) - scopus: 2-s2.0-33847172794 (351)

11573/358071 - 2007 - Indolyl Aryl Sulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Role of Two Halogen Atoms at the Indole Ring in Developing New Analogues with Improved Antiviral Activity
La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Bergamini, A.; Sinistro, A.; Cavazza, A.; Maga, G.; Samuele, A.; Zanoli, S.; Novellino, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5034-5038 - issn: 0022-2623 - wos: WOS:000249871300022 (53) - scopus: 2-s2.0-34948862163 (58)

11573/144595 - 2007 - Arylthioindole Inhibitors of Tubulin Polymerization. 3. Biological Evaluation, Structure−Activity Relationships and Molecular Modeling Studies
La Regina, Giuseppe; Edler, M. C.; Brancale, A.; Kandil, S.; Coluccia, Antonio; Piscitelli, Francesco; Hamel, E.; De Martino, G.; Matesanz, R.; Daz, J. F.; Scovassi, A. I.; Ennio, P.; Lavecchia, A.; Novellino, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2865-2874 - issn: 0022-2623 - wos: WOS:000247033900011 (193) - scopus: 2-s2.0-34250869030 (202)

11573/237477 - 2007 - Arylthioindoles: Design, Synthesis and Biological Activity
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Brancale, A.; Hamel, E.; Diaz, J. F.; Scovassi, A. I.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti, Italy)
book: Atti del Convegno - ()

11573/234427 - 2007 - Arylthioindoles: Docking and Molecular Dynamics Studies.
La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Minelli, L.; Brancale, A.; Kandil, S.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()

11573/395984 - 2007 - Indolilarilsolfoni, potenti e selettivi agenti anti-HIV
La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 7° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) (Riccione (RN))
book: 7° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) - ()

11573/237794 - 2007 - New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity.
La Regina, Giuseppe; Silvestri, Romano; Artico, Marino; Lavecchia, A.; Novellino, E.; Befani, O.; Turini, P.; Agostinelli, Enzo - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 922-931 - issn: 0022-2623 - wos: WOS:000244530400004 (124) - scopus: 2-s2.0-33847770688 (124)

11573/240105 - 2007 - PYRROLO[1,2-b][1,2,5]BENZOTHIADIAZEPINES (PBTDs) induce apoptosis in K562 cells.
Marfè, G.; Di Stefano, C.; Silvestri, Romano; Abruzzese, E.; Catalano, G.; Di Renzo, Livia Maria; Filomeni, G.; Giorda, E.; La Regina, Giuseppe; Morgante, E.; Ciriolo, M. R.; Russo, M. A.; Amadori, S.; Sinibaldi Salimei, P. - 01a Articolo in rivista
paper: BMC CANCER (London: BioMed Central, [2001]-) pp. 207- - issn: 1471-2407 - wos: WOS:000252786900001 (7) - scopus: 2-s2.0-38949085858 (9)

11573/238314 - 2007 - Synthesis of Indol Aryl Sulfones bearing Natural and Unnatural Aminoacids as Potent HIV-1 Non-Nucleoside Reverse Transcriptase.
Piscitelli, Francesco; La Regina, Giuseppe; Coluccia, Antonio; Sansone, A.; Giordano, C.; Bergamini, A.; Sinistro, A.; Cavazza, A.; Maga, G.; Samuele, A.; Zanoli, S.; Lavecchia, A.; Novellino, E.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()

11573/396620 - 2007 - Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-Pyrazole-3-Carboxamides as Potent Pyrrole Bioisosteres of Rimonabant and SR144528.
Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano; Cascio, M. G.; Lavecchia, A.; Brizzi, A.; Pasquini, S.; Botta, M.; Novellino, E.; Di Marzo, V.; Corelli, F. - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena)
book: Program and Abstracts - ()

11573/396664 - 2007 - Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides, as Potent Pyrrole Bioisosteres of Rimonabant and SR144528.
Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano; Cascio, M. G.; Lavecchia, A.; Brizzi, A.; Pasquini, S.; Botta, M.; Novellino, E.; Di Marzo, V.; Corelli, F. - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()

11573/363492 - 2007 - Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3-D QSAR studies.
Ragno, Rino; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: EXPERT OPINION ON DRUG DISCOVERY (--London United Kingdom:Informa Healthcare -London : Informa Healthcare, 2006-.) pp. 87-114 - issn: 1746-0441 - wos: WOS:000207616400006 (7) - scopus: 2-s2.0-34447527787 (7)

11573/237475 - 2007 - Induction of Apoptosis in Human Tumor Cells by a New Pyrazolcarboxamide
Scovassi, A. I.; Camboni, T.; Prosperi, E.; La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena, Italy)
book: Program and Abstracts - ()

11573/237900 - 2007 - Effects of a new arylthioindole on HeLa cell metabolism
Scovassi, A. I.; Giansanti, V.; Prosperi, E.; La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena)
book: Program and Abstracts - ()

11573/502809 - 2007 - Arylcarbonlyindoles: Antimitotic Agents and Potent Inhibitors of Tubulin Polymerization.
T., Sarkar; La Regina, Giuseppe; Silvestri, Romano; E., Hamel - 04a Atto di comunicazione a congresso
conference: American Society for Cell Biology (ASCB) 47th Annual Meeting (Washington, USA)
book: Abstracts - ()

11573/203690 - 2006 - Synthesis and evaluation of novel potential HCV helicase ihibitors.
Brancale, A; Vlachakis, D; Barbera, Mc; Silvestri, Romano; Berry, C; Netys, J. - 04a Atto di comunicazione a congresso
conference: 9th International Conference on Antiviral Research (San Juan, Porto Rico)
book: Abtracts - ()

11573/71187 - 2006 - Direct HPLC enantioseparation of chiral aptazepine derivatives on coated and bonded polysaccharide-based chiral stationery phases.
Cirilli, R; Orlando, Viviana; Ferretti, R; Turchetto, L; Silvestri, Romano; De Martino, G; La Torre, F. - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 621-632 - issn: 0899-0042 - wos: WOS:000239204000008 (31) - scopus: 2-s2.0-33750071730 (36)

11573/396668 - 2006 - Structure-Based and 3-D QSAR Drug Design of New Indolyl Aryl Sulfones.
Coluccia, Antonio; Ragno, Rino; La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()

11573/53434 - 2006 - Improved 3-D QSAR Model on Indolyl Aryl Sulfones: Design of potent anti-HIV-1 active against both wild type and mutant form of RT.
Coluccia, Antonio; Ragno, Rino; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: The 16th European Symposium on Quantitative Structure-Activity Relationships & Molecular Modelling (Civitavecchia)

11573/361589 - 2006 - New Arylthioindoles: Potent Inhibitors of Tubulin Polymerization. 2. Structure-Activity Relationships and Molecular Modeling Studies.
De Martino, G.; Edler, M. C.; La Regina, Giuseppe; Coluccia, Antonio; Barbera, M. C.; Barrow, D.; Nicholson, R. I.; Chiosis, G.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 947-954 - issn: 0022-2623 - wos: WOS:000235826300014 (372) - scopus: 2-s2.0-32344432249 (383)

11573/233924 - 2006 - Synthesis of Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): New Agents for the Treatment of Chronic Myelogenus Leukemia (CML).
De Martino, G.; La Regina, Giuseppe; Artico, Marino; Silvestri, Romano; Lavecchia, A.; Novellino, E. - 04a Atto di comunicazione a congresso
book: Atti del Congresso - ()

11573/144591 - 2006 - Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carbxamide.
De Martino, G.; La Regina, Giuseppe; Ragno, Rino; Coluccia, Antonio; Bergamini, A.; Caprini, C.; Sinistro, A.; Maga, G.; Crespan, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 59-77 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-33745100897 (45)

11573/396469 - 2006 - Arylthioindoles, Potent Inhibitors of Tubulin Polymerization: Structure-Activity Relationships and Molecular Modeling Studies.
La Regina, Giuseppe; Brancale, A.; De Martino, G.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()

11573/57661 - 2006 - Ariltioindoli, potenti inibitori della polimerizzazione della tubulina
La Regina, Giuseppe; Brancale, A.; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 6° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) (Riccione (RN))
book: 6° Sigma Aldrich Young Chemists Symposium - ()

11573/396674 - 2006 - New Indolyl Aryl Sulfones (IASs) as potent anti-HIV agents.
Piscitelli, Francesco; La Regina, Giuseppe; De Martino, G.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()

11573/359248 - 2006 - Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide
Ragno, Rino; Coluccia, Antonio; La Regina, Giuseppe; Gabriella De, Martino; Piscitelli, Francesco; Antonio, Lavecchia; Ettore, Novellino; Alberto, Bergamini; Chiara, Ciaprini; Anna, Sinistro; Giovanni, Maga; Emanuele, Crespan; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3172-3184 - issn: 0022-2623 - wos: WOS:000237832400018 (177) - scopus: 2-s2.0-33744831188 (184)

11573/57584 - 2006 - Indole nucleus as a selected pharmacophore for the design of novel highly anti-HIV RT inhibitors and also capable to inhibit tumor cell replication.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Ragno, Rino - 04a Atto di comunicazione a congresso
conference: Hosts, Symbionts and Parasites: Molecular and Pharmacological Approaches (Roma)
book: Abstracts - ()

11573/72150 - 2006 - Current state-of-the-art in preclinical and clinical development of novel non-nucleoside HIV-1 reverse transcriptase inhibitors
Silvestri, Romano; Giovanni, Maga - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare -London, United Kingdom: Ashley Publications Limited) pp. 939-962 - issn: 1354-3776 - wos: WOS:000202984700004 (11) - scopus: 2-s2.0-34247179717 (11)

11573/238618 - 2006 - Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): A New Class of Agents with High Apoptotic Activity in Chronic Myelogenous Leukemia K562 Cells and in Cells from Patients at Onset and Who Were Imatinib-Resistant.
Silvestri, Romano; Marfe', G.; Artico, Marino; La Regina, Giuseppe; La Vecchia, A.; Novellino, E.; Morgante, E.; Di Stefano, C.; Catalano, G.; Filomeni, G.; Abruzzese, E.; Ciriolo, M. R.; Russo, M.; Amadori, S.; Birilli, R.; La Torre, F.; Sinibaldi Solimei, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5840-5844 - issn: 0022-2623 - wos: WOS:000240495600019 (64) - scopus: 2-s2.0-33748877961 (66)

11573/138978 - 2005 - Comparative study between the polysaccharidebased Chiralcel OJ and Chiralcel OD CSPs in chromatographic enantioseparation of imidazole analogues of Fluoxetine and Miconazole.
Cirilli, R.; Ferretti, R.; Gallinella, B.; La Torre, F.; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF SEPARATION SCIENCE (WILEY-V C H VERLAG GMBH, PO BOX 10 11 61, WEINHEIM, GERMANY, D-69451) pp. 627-634 - issn: 1615-9314 - wos: WOS:000229160400004 (26) - scopus: 2-s2.0-19044400487 (27)

11573/233895 - 2005 - Arylthioindoles, Potent Inhibitors of Tubulin Polymerization.
De Martino, G.; La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Edler, M. C.; Barbera, M. C.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Second Joint Italian - Swiss Meeting on Medicinal Chemistry (Modena)
book: Abstracts - ()

11573/502726 - 2005 - Chiral resolution and binding study of 1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino[2,1-d]pyrrolo[1,2-b] [1,2,5]benzotriazepine (10-methyl-10-azaaptazepine) and 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo[1,2-b][1,2,5]-benzothiadiazepine 10,10-dioxide (tiaaptazepine).
De Martino, G.; La Regina, Giuseppe; La Torre, F.; Cirilli, R.; Mereghetti, I.; Cagnotto, A.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 931-937 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-27744558834 (2)

11573/235905 - 2005 - Dihalo Indolyl Aryl Sulfones (IASs) Highly Active In Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations.
De Martino, G.; La Regina, Giuseppe; Ragno, Rino; Coluccia, Antonio; Maga, G.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 20th International Congress of Heterocyclic Chemistry (Palermo)
book: Abstracts - ()

11573/138979 - 2005 - Novel 1-[2-(Diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. A Structure-Activity Relationship Investigation.
De Martino, G.; La Regina, Giuseppe; Ragno, Rino; Loddo, R.; La Colla, M.; Mura, M.; La Colla, P.; Maga, G.; Crespan, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4378-4388 - issn: 0022-2623 - wos: WOS:000230121800023 (51) - scopus: 2-s2.0-21244459659 (58)

11573/232365 - 2005 - Design, Synthesis and Biological Evaluation of New Pyrrole MAO-B Inhibitors.
La Regina, Giuseppe; De Martino, G.; Robortaccio, G.; Ragno, Rino; Befani, O.; Agostinelli, Enzo; Turini, Paola; Fabi, A.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()

11573/232310 - 2005 - High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme
R., Cancio; Silvestri, Romano; Ragno, Rino; Artico, Marino; G., De Martino; La Regina, Giuseppe; E., Crespan; S., Zanoli; U., Hubscher; S., Spadari; G., Maga - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 4546-4554 - issn: 0066-4804 - wos: WOS:000233020900016 (19) - scopus: 2-s2.0-27644482321 (22)

11573/359603 - 2005 - Docking and 3-D QSAR Studies on Indolyl Aryl Sulfones. Binding Mode Exploration at the HIV-1 Reverse Transcriptase Non-Nucleoside Binding Site and Design of Highly Active N-(2-Hydroxyethyl)carboxamide and N-(2-Hydroxyethyl)carbohydrazide Derivatives.
Ragno, Rino; Artico, Marino; De Martino, G.; La Regina, Giuseppe; Coluccia, Antonio; Di Pasquali, A.; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 213-223 - issn: 0022-2623 - wos: WOS:000226212900021 (73) - scopus: 2-s2.0-12144279076 (84)

11573/240140 - 2005 - Indolyl aryl Sulfones (IASs): Development of highly potent NNRTIs active against wt-HIV-1 and clinically relevant drug resistant mutants
Silvestri, Romano; Artico, Marino - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3779-3806 - issn: 1381-6128 - wos: WOS:000232839600006 (22) - scopus: 2-s2.0-27744462731 (21)

11573/203455 - 2004 - Studies of enantiomerization barrier of 1-[2-(2-methoxycarbonylacetamido) benzenesulfonyl]-1H-pyrrole by enantio selective dynamic HPLC.
Cirilli, R; Ferretti, R; La Torre, F; Gallinella, B; Zanitti, L; Silvestri, Romano; Di Pasquali, Alessandra; Pierini, M. - 04a Atto di comunicazione a congresso
conference: 25th International Symposium on Chromatograph (Parigi)
book: Book of Abstracts - ()

11573/396688 - 2004 - New Agents Highly Active in Cancer Therapy. Indoles, Potent Inhibitors of Tubulin Polymerization.
De Martino, G.; La Regina, Giuseppe; Barbera, M. C.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()

11573/396698 - 2004 - Arylthioindoles, Potent Inhibitors of Tubulin Polymerization.
De Martino, G.; La Regina, Giuseppe; Barbera, M. C.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Istituto Pasteur – Fondazione Cenci Bolognetti, Giornate Scientifiche Della Fondazione, Molecular Recognition (Roma)
book: Abstracts - ()

11573/396722 - 2004 - Potenti Inibitori della Tubulina a Struttura Indolica.
De Martino, G.; La Regina, Giuseppe; Barbera, M. C.; Brancale, A.; Hamel, E.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()

11573/360936 - 2004 - Arylthioindoles, potent inhibitors of tubulin polymerization.
De Martino, G.; La Regina, Giuseppe; Coluccia, Antonio; Edler, M. C.; Barbera, M. C.; Brancale, A.; Wilcox, E.; Hamel, E.; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6120-6123 - issn: 0022-2623 - wos: WOS:000225409400003 (280) - scopus: 2-s2.0-10044236627 (292)

11573/396700 - 2004 - Novel Indolyl Aryl Sulfones (IAAs) Highly Active in Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations.
De Martino, G.; La Regina, Giuseppe; Crespan, E.; Maga, G.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Cost D28 MC Action. Natural Products as a Source for Discovery, Synthesis, and Application of New Pharmaceuticals. (Siena)
book: Program & Abstracts - ()

11573/396712 - 2004 - Nuovi Indolil Aril Solfoni 2-Sostituiti Attivi su HIV-1 WT e su Altri Mutanti Resistenti.
De Martino, G.; La Regina, Giuseppe; Crespan, E.; Maga, G.; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()

11573/396687 - 2004 - Studies on Novel Agents for Depression and Parkinson’s Disease. Potent Pyrrole and Indole Monoamine Oxidase Inhibitors.
La Regina, Giuseppe; De Martino, G.; Di Pasquali, A.; Ragno, Rino; Befani, O.; Agostinelli, Enzo; Turini, Paola; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()

11573/396732 - 2004 - Potenti Inibitori delle Monoamino Ossidasi a Struttura Pirrolica ed Indolica.
La Regina, Giuseppe; De Martino, G.; Di Pasquali, A.; Ragno, Rino; Befani, O.; Palumbo, M.; Agostinelli, Enzo; Turini, Paola; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()

11573/396702 - 2004 - Imidazole Derivatives Highly Active Against Candida Albicans.
La Regina, Giuseppe; De Martino, G; D’Auria F., D; Nencioni, Lucia; Palamara, Anna Teresa; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Cost D28 MC Action. Natural Products as a Source for Discovery, Synthesis, and Application of New Pharmaceuticals. (Siena)
book: Program & Abstracts - ()

11573/396498 - 2004 - Chemotherapeutic Agents for the Treatment of Fungal Infections. Imidazole Derivatives HighlyActive Against Candida albicans.
La Regina, Giuseppe; De Martino, G; Di Pasquali, A; D’Auria F., D; Nencioni, Lucia; Palamara, Anna Teresa; Artico, M; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()

11573/396727 - 2004 - Derivati Imidazolici Isomeri dell’Econazolo ad Azione Anti-Candida.
La Regina, Giuseppe; De Martino, G; Di Pasquali, A; D’Auria F., D; Nencioni, Lucia; Palamara, Anna Teresa; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()

11573/233541 - 2004 - Simple, Short Peptide Derivatives of L-737,126 Active In Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations.
Silvestri, Romano; Artico, Marino; De Martino, G.; La Regina, Giuseppe; Loddo, R.; La Colla, M.; Mura, M.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3892-3896 - issn: 0022-2623 - wos: WOS:000222530700019 (53) - scopus: 2-s2.0-3142651936 (56)

11573/502712 - 2004 - Imidazole Analogues of Fluoxetine, a Novel Class of Anti-Candida Agents.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; A., Di Pasquali; G., De Martino; D'auria, Felicia Diodata; Nencioni, Lucia; Palamara, Anna Teresa - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3924-3926 - issn: 0022-2623 - wos: WOS:000222856800004 (56) - scopus: 2-s2.0-3242778536 (59)

11573/239423 - 2004 - Synthetic approaches to difluoroindolecarboxylic acid ethyl esters.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; De Martino, G. - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 26-31 - issn: 1551-7012 - wos: WOS:000222493900003 (5) - scopus: 2-s2.0-2942631454 (6)

11573/238383 - 2004 - Anti-HIV-1 Activity of Pyrryl Aryl Sulfone (PAS) Derivatives: Synthesis and SAR Studies of Novel Esters and Amides at the Position 2 of the Pyrrole Nucleus.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; De Martino, G.; La Colla, M.; Loddo, R.; La Colla, P. - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001 Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 201-210 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-1342321756 (44)

11573/189709 - 2003 - Analoghi azolici della fluoxetina, una nuova classe di agenti antifungini
D'auria, Felicia Diodata; Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; De Martino, G.; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
conference: 31° Congresso Nazionale Società Italiana di Microbiologia (Roma)
book: Riassunti - ()

11573/396740 - 2003 - Docking and 3-D QSAR Studies on Indolyl Aryl Solfones (IASs). Binding Mode Exploration at the HIV-1 RT NNBS and Structure Based Drug Design.
Ragno, Rino; Silvestri, Romano; De Martino, G.; La Regina, Giuseppe; Artico, Marino; Massa, S.; Marongiu, M.; Attori, M.; Marongiu, E.; Cabras, A.; Saddi, M.; La Colla, P. - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()

11573/218643 - 2003 - N-Benzyl and N-propargyl 1H-pyrrole-2-carboxyamides, as simple and effective monoamine oxidase inhibitors.
Silvestri, Romano; Artico, Marino; La Regina, G.; De Martino, G.; Massa, S.; Befani, Olivia; Palumbo, M.; Turini, Paola; Agostinelli, Enzo - 13a Altro ministeriale

11573/249931 - 2003 - Novel Indolyl Aryl Sulfones Active against HIV-1 Carrying NNRTI Resistance Mutations: Synthesis and SAR Studies.
Silvestri, Romano; De Martino, G.; La Regina, Giuseppe; Artico, Marino; Massa, S.; Vargiu, L.; Mura, M.; Loi, A. G.; Marceddu, T.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2482-2493 - issn: 0022-2623 - wos: WOS:000183220400024 (171) - scopus: 2-s2.0-12444315080 (181)

11573/396772 - 2003 - Azole Analogues of Fluoxetine, a Novel Class of anti-Candida Agents.
Silvestri, Romano; La Regina, Giuseppe; De Martino, G.; Artico, Marino; D’Auria, F. D.; Palamara, A. T. - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()

11573/57586 - 2003 - Pyrrolo[1,2-b]benzothiadiazepines (PBTDs) induce Apoptosis in Chronic Myelogenous K562 Leucemic Cells
Silvestri, Romano; La Regina, Giuseppe; De Martino, G.; Artico, Marino; Marfe', G.; Sinibaldi Salimei, P.; Morgante, E.; Russo, M. A.; Di Stefano, C. - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()

11573/396947 - 2003 - Synthesis of Indole Derivatives active against Flaviviridae Viruses.
Silvestri, Romano; La Regina, Giuseppe; De Martino, G.; Artico, Marino; Massa, S.; Marongiu, M.; Attori, M.; Cabras, A.; Saddi, M.; La Colla, P. - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()

11573/255841 - 2003 - Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B
Silvestri, Romano; La Regina, Giuseppe; Gabriella De, Martino; Marino, Artico; Olivia, Befani; Marianna, Palumbo; Agostinelli, Enzo; Turini, Paola - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 917-920 - issn: 0022-2623 - wos: WOS:000181399100004 (47) - scopus: 2-s2.0-0037435063 (47)

11573/252766 - 2002 - Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase
Silvestri, Romano; Artico, Marino; Gabriella De, Martino; Ragno, Rino; Silvio, Massa; Roberta, Loddo; Chiara, Murgioni; Anna Giulia, Loi; Paolo La, Colla; Alessandra, Pani - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1567-1576 - issn: 0022-2623 - wos: WOS:000174844600004 (67) - scopus: 2-s2.0-0037061639 (66)

11573/396788 - 2002 - N-Benzyl and N-Propargyl 1H-Pyrrole-2-carboxyamides, as Simple and Potent MAO Inhibitors.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; De Martino, G.; Massa, S.; Befani, O.; Palumbo, M.; Agostinelli, Enzo; Turini, Paola - 04a Atto di comunicazione a congresso
conference: 23rd IUPAC – 2002. International Symposium on the Chemistry of Natural Products (Firenze)
book: Abstracts Book - ()

11573/396787 - 2002 - N-Benzil e N-Propargil 1H-Pirrolo-2-carbossiamidi, Semplici ed Efficaci Inibitori delle Monoamino Ossidasi.
Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; De Martino, G.; Massa, S.; Befani, P.; Palumbo, M.; Agostinelli, Enzo; Turini, Paola - 04a Atto di comunicazione a congresso
conference: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica (Sorrento)
book: Atti del Convegno - ()

11573/253535 - 2002 - Anti-HIV-1 NNRT Agents: Acylamino Pyrryl Aryl Sulfones (APASs) as Truncated Analogues of Tricyclic PBTDs.
Silvestri, Romano; De Martino, G.; Artico, Marino; La Regina, Giuseppe; Ragno, Rino; Loddo, P.; La Colla, P.; Marongiu, M. E.; La Colla, M.; Pani, A. - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 195-218 - issn: 1054-2523 - wos: WOS:000178074100001 (8) - scopus: 2-s2.0-0036439429 (9)

11573/396783 - 2002 - Agenti anti-HIV-1: Acilamino Pirril Aril Solfoni (APAS), Analoghi Troncati delle PBTD Tricicliche.
Silvestri, Romano; De Martino, G.; La Regina, Giuseppe; Artico, Marino; Ragno, Rino; La Colla, M.; Loddo, R.; Marongiu, M. E.; La Colla, P.; Pani, A. - 04a Atto di comunicazione a congresso
conference: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica (Sorrento)
book: Atti del Convegno - ()

11573/396801 - 2002 - Anti-HIV-1 NNRT Agents: Acylamino Pyrryl Aryl Sulfones (APASs) as Truncated Analogues of Tricyclic PBTDs.
Silvestri, Romano; De Martino, G.; La Regina, Giuseppe; Artico, Marino; Ragno, Rino; La Colla, P.; Marongiu, M. E.; Pani, A. - 04a Atto di comunicazione a congresso
conference: 23rd IUPAC – 2002. International Symposium on the Chemistry of Natural Products (Firenze)
book: Abstracts Book - ()

11573/72141 - 2002 - A simplified synthesis of ethyl 5-chloro-6-fluro-1H-indole-2-carboxylate and ethyl 5-chloro-4-fluro-1H-indole-2-carboxylate
Silvestri, Romano; De Martino, G.; Sbardella, G. - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 507-510 - issn: 0030-4948 - wos: (0) - scopus: 2-s2.0-0036796527 (7)

11573/53418 - 2002 - Attività anti-HIV-1 di Ariltiazolilcarbossiamidi, Nuova Classe di NNRTI ibridi tra PETT, UC781 e TDA
Silvestri, Romano; Gianluca, Sbardella; Gabriella De, Martino; Artico, Marino; Ragno, Rino; Roberta, Loddo; Massimiliano La, Colla; Paolo La, Colla; Maria E., Marongiu; And Alessandra, Pani - 04a Atto di comunicazione a congresso
book: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica della SCI - ()

11573/256233 - 2000 - Structure based design, synthesis and biological evaluation of novel pyrrolyl aryl sulfones (PASs) active at nanomolar concentration as HIV-1 non nucleoside reverse transcriptase inhibitors.
Artico, Marino; Silvestri, Romano; Pagnozzi, E.; Bruno, B.; Novellino, E.; Greco, G.; Massa, S.; Ettorre, A.; Loi, A. G.; Scintu, F.; La Colla, P. - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1886-1891 - issn: 0022-2623 - wos: WOS:000086969400025 (136) - scopus: 2-s2.0-0034075488 (138)

11573/453053 - 1992 - AROMATIC HYDRAZIDES AS SPECIFIC INHIBITORS OF BOVINE SERUM AMINE OXIDASE
Artico, Marino; Silvestri, Romano; Stefancich, ; A. V. I. G. L. I. A. N. O. L., Maccarrone Digiulio; Agostinelli, Enzo - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 219-228 - issn: 0223-5234 - wos: WOS:A1992HX47900005 (29) - scopus: 2-s2.0-0026716029 (29)

11573/470215 - 1992 - Research on antibacterial and antifungal agents. 16. Synthesis and antifungal activities of 1-[α-(1-naphthyl)benzyl]imidazole derivatives and related 2-naphthyl isomers
Artico, Marino; Stefancich, Giorgio; Silvestri, Romano; Massa, Silvio; G., Apuzzo; Artico, Marco; G., Simonetti - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 693-699 - issn: 0223-5234 - wos: WOS:A1992JZ82500006 (17) - scopus: 2-s2.0-0026458733 (17)

11573/70421 - 1992 - Bovine Serum Amine Oxidase: Half-Site Reactivity with Phenylhydrazine, Semicarbazide and Aromatic Hydrazides.
Laura, Morpurgo; Agostinelli, Enzo; Mondovi', Bruno; Luciana, Avigliano; Silvestri, Romano; Artico, Marino - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 2615-2621 - issn: 0006-2960 - wos: WOS:A1992HH48900023 (59) - scopus: 2-s2.0-0026562320 (59)

11573/470114 - 1992 - Antibacterial and antifungal agents. XV. Synthesis and antifungal activity of structural analogues of bifonazole and ketoconazole.
Stefancich, Giorgio; Artico, Marco; Ortar, Giorgio; Silvestri, Romano; Simonetti, Giovanna; Germana, Apuzzo; Artico, Marino - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 687-694 - issn: 0365-6233 - wos: WOS:A1992JZ63600001 (5) - scopus: 2-s2.0-0026948071 (5)

11573/470167 - 1992 - Researches on antibacterial and antifungal agents, XIV: Thiophene analogues of bifonazole
Stefancich, Giorgio; Silvestri, Romano; Retico, Augusta; Artico, Marco; Simonetti, Giovanna - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 199-204 - issn: 0365-6233 - wos: WOS:A1992HR85900002 (13) - scopus: 2-s2.0-0026563544 (14)

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