11573/1667362 - 2023 -
Toll-like receptor 4-dependent platelet-related thrombosis in SARS-CoV-2 infection Carnevale, Roberto; Cammisotto, Vittoria; Bartimoccia, Simona; Nocella, Cristina; Castellani, Valentina; Bufano, Marianna; Loffredo, Lorenzo; Sciarretta, Sebastiano; Frati, Giacomo; Coluccia, Antonio; Silvestri, Romano; Ceccarelli, Giancarlo; Oliva, Alessandra; Venditti, Mario; Pugliese, Francesco; Mastroianni, Claudio Maria; Turriziani, Ombretta; Leopizzi, Martina; D'amati, Giulia; Pignatelli, Pasquale; Violi, Francesco - 01a Articolo in rivista
paper: CIRCULATION RESEARCH (Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
PRimo editore:
Baltimore, Md. : Grune & Stratton, c1953-) pp. 290-305 - issn: 0009-7330 - wos: WOS:000924202600003 (1) - scopus: 2-s2.0-85147310768 (1)
11573/1669754 - 2023 -
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo Sebastiani, Jessica; Puxeddu, Michela; Nalli, Marianna; Altieri, Ludovica; Fionda, Cinzia; Masci, Domiziana; Bertoni, Federico; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ([Paris] : Elsevier, [198?]-) pp. - - issn: 1768-3254 - wos: WOS:000902003000001 (0) - scopus: 2-s2.0-85145425603 (0)
11573/1669812 - 2023 -
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations Puxeddu, Michela; La Regina, Giuseppe; Silvestri, Romano; Borioni, Andrea; Cirilli, Raffaela - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. 431- - issn: 1420-3049 - wos: WOS:000909218800001 (0) - scopus: 2-s2.0-85145678833 (0)
11573/1616528 - 2022 -
Anticancer activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a new dishevelled 1 inhibitor Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe; Puxeddu, Michela; Toto, Angelo; Paone, Alessio; Bouzidi, Amani; Orlando, Viviana; Biagioni, Stefano; Masci, Domiziana; Cantatore, Chiara; Cutruzzola', Francesca; Gianni, Stefano; Silvestri, Romano - 01a Articolo in rivista
paper: CANCERS (Basel : MDPI) pp. - - issn: 2072-6694 - wos: WOS:000773498900001 (1) - scopus: 2-s2.0-85131007159 (1)
11573/1622472 - 2022 -
Single-run chemo- and enantio-selective high-performance liquid chromatography separation of tramadol and its principal metabolite, O-desmethyltramadol, using a chlorinated immobilized amylose-based chiral stationary phase under multimodal elution conditions La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: SEPARATION SCIENCE PLUS (Hoboken New Jersey : John Wiley) pp. 99-104 - issn: 2573-1815 - wos: WOS:000757674000001 (0) - scopus: 2-s2.0-85147396296 (0)
11573/1622488 - 2022 -
Modulating undruggable targets to overcome cancer therapy resistance La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: DRUG RESISTANCE UPDATES (W B Saunders Company:Fulfillment Department, The Curtis Center, Independence Square West:Philadelphia, PA 19106:(800)654-2452, (215)238-7800, EMAIL: wbspcs@harcourt.com, INTERNET: http://elsevierhealth.com, Fax: (215)238-6445) pp. - - issn: 1368-7646 - wos: WOS:000758804000001 (5) - scopus: 2-s2.0-85124496115 (5)
11573/1645691 - 2022 -
Exploring CCRL2 chemerin binding using accelerated molecular dynamics Bufano, Marianna; Laffranchi, Mattia; Sozzani, Silvano; Raimondo, Domenico; Silvestri, Romano; Coluccia, Antonio - 01a Articolo in rivista
paper: PROTEINS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. - - issn: 0887-3585 - wos: WOS:000788507200001 (1) - scopus: 2-s2.0-85128889142 (2)
11573/1660747 - 2022 -
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment Di Magno, Laura; Coluccia, Antonio; Bufano, Marianna; Ripa, Silvia; La Regina, Giuseppe; Nalli, Marianna; Di Pastena, Fiorella; Canettieri, Gianluca; Silvestri, Romano; Frati, Luigi - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 114605- - issn: 0223-5234 - wos: WOS:000834164000003 (1) - scopus: 2-s2.0-85134696311 (1)
11573/1662369 - 2022 -
EFFICACY AND SAFETY OF A NOVEL FOOD SUPPLEMENT IN THE TREATMENT OF FUNCTIONAL DYSPEPSIA: A PILOT OPEN STUDY Innocenti, Matteo; Silvestri, Romano - 01a Articolo in rivista
paper: AGRO FOOD INDUSTRY HI-TECH (Milano : Teknoscienze srl) pp. - - issn: 1722-6996 - wos: (0) - scopus: (0)
11573/1664745 - 2022 -
Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor Puxeddu, Michela; D'ambrosio, Michele; Nalli, Marianna; Coluccia, Antonio; Manetto, Simone; Ciogli, Alessia; Masci, Domiziana; Fionda, Cinzia; Coni, Sonia; Bordone, Rosa; Canettieri, Gianluca; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 15805-15818 - issn: 0022-2623 - wos: WOS:000888017600001 (0) - scopus: 2-s2.0-85142634063 (0)
11573/1669809 - 2022 -
Emerging Direct Targeting β-Catenin Agents Nalli, Marianna; Masci, Domiziana; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. 7735- - issn: 1420-3049 - wos: WOS:000887474600001 (0) - scopus: 2-s2.0-85142604566 (0)
11573/1554505 - 2021 -
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme Puxeddu, Michela; Nalli, Marianna; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 173936-173936 - issn: 0014-2999 - wos: WOS:000628752700009 (7) - scopus: 2-s2.0-85102892586 (7)
11573/1554523 - 2021 -
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia Puxeddu, Michela; Coluccia, Antonio; Bufano, Marianna; Nalli, Marianna; Sebastiani, Jessica; Orlando, Viviana; Biagioni, Stefano; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 1-18 - issn: 0223-5234 - wos: WOS:000661282500029 (10) - scopus: 2-s2.0-85106600720 (11)
11573/1554566 - 2021 -
RS4651 suppresses lung fibroblast activation via the TGF-β1/SMAD signalling pathway La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACOLOGY (AMSTERDAM, NETHERLANDS: ELSEVIER SCIENCE) pp. 174135-174135 - issn: 0014-2999 - wos: WOS:000657380100001 (2) - scopus: 2-s2.0-85105328489 (2)
11573/1573217 - 2021 -
RS-5645 attenuates inflammatory cytokine storm induced by SARS-CoV-2 spike protein and LPS by modulating pulmonary microbiota La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (Lake Haven, N.S.W., Australia : Ivyspring International, c2004-) pp. 3305-3319 - issn: 1449-2288 - wos: WOS:000685459400004 (4) - scopus: 2-s2.0-85113771922 (4)
11573/1579282 - 2021 -
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer Nardella, Caterina; Visconti, Lorenzo; Malagrinò, Francesca; Pagano, Livia; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Gianni, Stefano; Toto, Angelo - 01a Articolo in rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. - - issn: 1745-6150 - wos: WOS:000706722300001 (2) - scopus: 2-s2.0-85117321017 (3)
11573/1587169 - 2021 -
Enantiomerization barrier of 1-[2-(2-methyl-2-methoxycarbonylacetamido) benzenesulfonyl]-1h-pyrrole studied by enantioselective dynamic HPLC, classical off column technique and computational approach Buonsenso, Fabio; Silvestri, Romano; Pierini, Marco - 04f Poster
conference: Merck Young Chemists' Symposium XX edition (Rimini)
book: Proceedings of the Merck Young Chemists' Symposium XX edition - (978-88-94952-25-4)
11573/1604507 - 2021 -
Discovery of a novel class of norovirus inhibitors with high barrier of resistance Puxeddu, Michela; La Regina, Giuseppe; Sebastiani, Jessica; Nalli, Marianna; Silvestri, Romano - 01a Articolo in rivista
paper: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:000711764700001 (0) - scopus: 2-s2.0-85116529403 (0)
11573/1604509 - 2021 -
Emerging therapeutic agents for colorectal cancer Nalli, Marianna; Puxeddu, Michela; La Regina, Giuseppe; Gianni, Stefano; Silvestri, Romano - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. 7463-7463 - issn: 1420-3049 - wos: WOS:000736380500001 (7) - scopus: 2-s2.0-85121522712 (7)
11573/1662370 - 2021 -
A METHOD TO MEASURE THE BARRIER EFFECT OF DRUGS AND ITS APPLICATION IN THE STUDY OF HYDROLYZED COLLAGEN Silvestri, Romano; Innocenti, Matteo - 01a Articolo in rivista
paper: AGRO FOOD INDUSTRY HI-TECH (Milano : Teknoscienze srl) pp. - - issn: 1722-6996 - wos: (0) - scopus: (0)
11573/1033380 - 2020 -
Selenotriapine - an isostere of the most studied thiosemicarbazone with pronounced pro-apoptotic activity, low toxicity and ability to challenge phenotype reprogramming of 3-D mammary adenocarcinoma tumors Pelliccia, Sveva; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ARABIAN JOURNAL OF CHEMISTRY (Amsterdam : Elsevier) pp. 1466-1489 - issn: 1878-5352 - wos: WOS:000505076000109 (5) - scopus: 2-s2.0-85037552505 (6)
11573/1336446 - 2020 -
Design, synthesis and discovery of novel N,N'-carbazoyl-aryl-urea inhibitors of Zika NS5 methyltransferase and virus replication. Spizzichino, Sharon; Silvestri, Romano - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 385-390 - issn: 1860-7187 - wos: WOS:000505817500001 (9) - scopus: 2-s2.0-85078073812 (10)
11573/1338475 - 2020 -
Discovery of new 1,1'-biphenyl-4-sulfonamides as selective subnanomolar human carbonic anhydrase II inhibitors La Regina, Giuseppe; Puxeddu, Michela; Nalli, Marianna; Silvestri, Romano - 01f Lettera, Nota
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 633-637 - issn: 1948-5875 - wos: WOS:000535281200005 (1) - scopus: 2-s2.0-85075123548 (1)
11573/1338485 - 2020 -
Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies Puxeddu, Michela; Coluccia, Antonio; Nalli, Marianna; Mazzoccoli, Carmela; Orlando, Viviana; Biagioni, Stefano; Mazzoni, Cristina; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000503099900046 (3) - scopus: 2-s2.0-85075503012 (4)
11573/1436287 - 2020 -
Discovery of Zika virus NS2B/NS3 inhibitors that prevent mice from fife-threatening infection and brain damage Coluccia, Antonio; Puxeddu, Michela; Nalli, Marianna; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 1869-1874 - issn: 1948-5875 - wos: WOS:000580567800013 (11) - scopus: 2-s2.0-85089122411 (11)
11573/1436323 - 2020 -
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains Nalli, Marianna; Masci, Domiziana; Coluccia, Antonio; Cinquina, Elisabetta; Turriziani, Ombretta; Falasca, Francesca; Catalano, Myriam; Limatola, Cristina; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. - - issn: 0223-5234 - wos: WOS:000600384300005 (8) - scopus: 2-s2.0-85090028457 (7)
11573/1436420 - 2020 -
Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics Bufano, Marianna; Nalli, Marianna; Silvestri, Romano; Coluccia, Antonio - 01a Articolo in rivista
paper: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (-SPRINGER, VAN GODEWIJCKSTRAAT 30, DORDRECHT, NETHERLANDS, 3311 GZ
-Kluwer Academic Publishers:Journals Department, PO Box 322, 3300 AH Dordrecht Netherlands:011 31 78 6576050, EMAIL: frontoffice@wkap.nl, kluweronline@wkap.nl, INTERNET: http://www.kluwerlaw.com, Fax: 011 31 78 6576254) pp. - - issn: 0920-654X - wos: WOS:000551348400001 (2) - scopus: 2-s2.0-85088437648 (1)
11573/1451071 - 2020 -
Sulfonamide inhibitors of beta-catenin signaling as anticancer agents with different output on c-Myc Di Magno, Laura; Di Pastena, Fiorella; Puxeddu, Michela; La Regina, Giuseppe; Coluccia, Antonio; Ciogli, Alessia; Manetto, Simone; Maroder, Marella; Canettieri, Gianluca; Silvestri, Romano; Nalli, Marianna - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 2264-2268 - issn: 1860-7179 - wos: WOS:000577594900001 (3) - scopus: 2-s2.0-85092511066 (3)
11573/1452337 - 2020 -
Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites Di Matteo, Adele; Coluccia, Antonio; Lo Sciuto, Alessandra; Travaglini Allocatelli, Carlo; Silvestri, Romano - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London : Nature Publishing Group) pp. 11276- - issn: 2045-2322 - wos: WOS:000548559600037 (4) - scopus: 2-s2.0-85087717252 (5)
11573/1456152 - 2020 -
Targeting the interaction between the SH3 domain of Grb2 and Gab2 Malagrinò, Francesca; Coluccia, Antonio; Bufano, Marianna; La Regina, Giuseppe; Puxeddu, Michela; Toto, Angelo; Visconti, Lorenzo; Paone, Alessio; Magnifico, Maria Chiara; Troilo, Francesca; Cutruzzola', Francesca; Silvestri, Romano; Gianni, Stefano - 01a Articolo in rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. 2435- - issn: 2073-4409 - wos: WOS:000592940700001 (4) - scopus: 2-s2.0-85096028884 (4)
11573/1487109 - 2020 -
HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53 Silvestri, Romano - 01a Articolo in rivista
paper: NEURO-ONCOLOGY (Carden Jennings Pub.) pp. 550-562 - issn: 1522-8517 - wos: WOS:000537427200015 (8) - scopus: 2-s2.0-85083545548 (8)
11573/1223718 - 2019 -
Drug design and synthesis of first in class PDZ1 targeting NHERF1 inhibitors as anticancer agents Coluccia, Antonio; La Regina, Giuseppe; Naccarato, Valentina; Nalli, Marianna; Orlando, Viviana; Biagioni, Stefano; Gautier, Candice Natacha Anna; Gianni, Stefano; Di Pastena, Fiorella; Di Magno, Laura; Canettieri, Gianluca; Silvestri, Romano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 499-503 - issn: 1948-5875 - wos: WOS:000464767700019 (11) - scopus: 2-s2.0-85064264813 (11)
11573/1223723 - 2019 -
Towards modern anticancer agents that interact with tubulin La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (Amsterdam Netherlands: Elsevier BV) pp. 58-68 - issn: 0928-0987 - wos: WOS:000460399800006 (29) - scopus: 2-s2.0-85061343987 (31)
11573/1266997 - 2019 -
Small molecule inhibitors of KDM5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing Jarid1b Pippa, Simone; Licursi, Valerio; Bombardi, Luca; Colotti, Gianni; Mollica, Adriano; Coluccia, Antonio; Naccarato, Valentina; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000469518100098 (16) - scopus: 2-s2.0-85065652898 (17)
11573/1278540 - 2019 -
First in class pdz1 targeting NHERF1 inhibitors as anticancer agents La Regina, Giuseppe; Naccarato, Valentina; Puxeddu, Michela; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 12th European Workshop in Drug Design (Siena)
book: Book of Abstract - ()
11573/1278549 - 2019 -
Inhibition of human Norovirus replication by a novel class of oindolylarylsulfones in vitro and in zebrafish larvae Naccarato, Valentina; La Regina, Giuseppe; Silvestri, Romano - 04f Poster
conference: 32nd International Conference on Antiviral Research (Baltimora, Stati Uniti)
book: Program and Abstracts - ()
11573/1278679 - 2019 -
New anti-cancer agents through an interaction with tubulin La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Silvestri, Romano - 04f Poster
conference: New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours - First Working-Group Meeting (Torino (TO))
book: Abstract Book - ()
11573/1278685 - 2019 -
Nitrogen donor ligands and their coordination compounds as a tool for treatment of multi drug resistant tumors Silvestri, Romano; La Regina, Giuseppe; Pelliccia, Sveva - 04f Poster
conference: New Diagnostic and Therapeutic Tools against Multidrug-Resistant Tumours - First Working-Group Meeting (Torino (TO))
book: Abstract Book - ()
11573/1282534 - 2019 -
Nox2-mediated platelet activation by glycoprotein (GP) VI: Effect of rivaroxaban alone and in combination with aspirin Cammisotto, Vittoria; Carnevale, Roberto; Nocella, Cristina; Stefanini, Lucia; Bartimoccia, Simona; Coluccia, Antonio; Silvestri, Romano; Pignatelli, Pasquale; Pastori, Daniele; Violi, Francesco - 01a Articolo in rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited
-London ; New York : Pergamon Press, 1958-) pp. 111-118 - issn: 0006-2952 - wos: WOS:000466060000011 (14) - scopus: 2-s2.0-85061548638 (15)
11573/1284052 - 2019 -
Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: structure-activity relationships and mode of action studies Masci, Domiziana; Coluccia, Antonio; Conforti, Irene; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 500-514 - issn: 0223-5234 - wos: WOS:000480664100037 (17) - scopus: 2-s2.0-85067210411 (17)
11573/1338507 - 2019 -
Small molecule inhibitors of kdm5 histone demethylases increase the radiosensitivity of breast cancer cells overexpressing JARID1B La Regina, Giuseppe; Naccarato, Valentina; Masci, Domiziana; Puxeddu, Michela; Nalli, Marianna; Coluccia, Antonio; Negri, Rodolfo; Silvestri, Romano - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()
11573/1338512 - 2019 -
Design, synthesis and biological evaluation of PDZ1 targeting NHERF1 inhibitors as anticancer agents La Regina, Giuseppe; Naccarato, Valentina; Masci, Domiziana; Bufano, Marianna; Nalli, Marianna; Coluccia, Antonio; Orlando, Viviana; Canettieri, Gianluca; Gianni, Stefano; Silvestri, Romano - 04f Poster
conference: XXVI National Meeting in Medicinal Chemistry - XII Young Medicinal Chemists’ Symposium (Milano)
book: Abstract Book - ()
11573/1338740 - 2019 -
Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: CARDIOVASCULAR RESEARCH (editore attuale:
ELSEVIER SCIENCE BV, PO BOX 211, AMSTERDAM, NETHERLANDS, 1000 AE
primo editore:
BMJ / British Medical Journal Publishing Group:PO Box 299, London WC1H 9TD United Kingdom:011 44 20 73836270, EMAIL: subscriptions@bmjgroup.com, INTERNET: http://www.bmjpg.com/bmj, Fax: 011 44 20 73836402) pp. 1766-1777 - issn: 0008-6363 - wos: WOS:000491246600015 (22) - scopus: 2-s2.0-85072535959 (22)
11573/1019836 - 2018 -
Arginine- and lysine-rich peptides: synthesis, characterization and antimicrobial activity Mollica, Adriano; Stefanucci, Azzurra; Carradori, Simone; Di Giulio , Anna Maria; Cellini, Lorenzo; Silvestri, Romano; Giordano, Cesare Giovanni; Scipioni, Anita; Punzi, Pasqualina - 01a Articolo in rivista
paper: LETTERS IN DRUG DESIGN & DISCOVERY (Bentham Science Publishers Ltd) pp. 220-226 - issn: 1570-1808 - wos: WOS:000423791700002 (11) - scopus: 2-s2.0-85042152424 (16)
11573/1071883 - 2018 -
A negative allosteric modulator of WNT receptor frizzled 4 switches into an allosteric agonist La Regina, Giuseppe; Passacantilli, Sara; Silvestri, Romano - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 839-851 - issn: 0006-2960 - wos: WOS:000424723300047 (16) - scopus: 2-s2.0-85041457316 (16)
11573/1071891 - 2018 -
β-catenin knockdown promotes nherf1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy Coluccia, Antonio; La Regina, Giuseppe; Famiglini, Valeria; Naccarato, Valentina; Bonetti, Daniela; Gautier, Candice Natacha Anna; Gianni, Stefano; Silvestri, Romano - 01a Articolo in rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3301-3316 - issn: 0950-9232 - wos: WOS:000435526600009 (14) - scopus: 2-s2.0-85044095990 (15)
11573/1072456 - 2018 -
Indolylarylsulfones, a fascinating story of highly potent human immunodeficiency virus type 1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 1-19 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-85064224696 (11)
11573/1117651 - 2018 -
New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Famiglini, Valeria; Nalli, Marianna; Masci, Domiziana; Verrico, Annalisa; Mazzoccoli, Carmela; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 283-297 - issn: 0223-5234 - wos: WOS:000435048900023 (23) - scopus: 2-s2.0-85046738606 (23)
11573/1117672 - 2018 -
Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects Carnevale, Roberto; Silvestri, Romano; Loffredo, Lorenzo; Novo, Marta; Cammisotto, Vittoria; Bartimoccia, Simona; Nocella, Cristina; Violi, Francesco - 01a Articolo in rivista
paper: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 1566-1574 - issn: 0306-5251 - wos: WOS:000435440600019 (53) - scopus: 2-s2.0-85046287954 (59)
11573/1117718 - 2018 -
New 6- and 7-heterocyclyl-1H-indole derivatives as potent tubulin assembly and cancer cell growth inhibitors La Regina, Giuseppe; Naccarato, Valentina; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: Seventh European Workshop in Drug Synthesis (Siena)
book: Seventh European Workshop in Drug Synthesis - ()
11573/1118125 - 2018 -
Indolylarylsulfones with potent anti-HIV-1 activity Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 31st International Conference on Antiviral Research (Porto, Portogallo)
book: Program and Abstracts - ()
11573/1170129 - 2018 -
Treating chronic myeloid leukemia by inhibition of tubulin polymerization La Regina, Giuseppe; Coluccia, Antonio; Naccarato, Valentina; Silvestri, Romano - 04b Atto di convegno in volume
conference: Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry (Palermo)
book: Book of Abstracts - ()
11573/1174760 - 2018 -
Structure-based drug design of potent pyrazole derivatives against Rhinovirus replication Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8402-8416 - issn: 0022-2623 - wos: WOS:000446142000022 (21) - scopus: 2-s2.0-85053181101 (22)
11573/1200815 - 2018 -
A high-throughput screening of a chemical compound library in ovarian cancer stem cells Silvestri, Romano; Ingallina, Cinzia; Botta, Bruno - 01a Articolo in rivista
paper: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 50-56 - issn: 1386-2073 - wos: WOS:000427836800007 (3) - scopus: 2-s2.0-85048467638 (3)
11573/1286679 - 2018 -
Indolylarylsulfones as novel potent anti-HIV-1 agents Masci, Domiziana; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04d Abstract in atti di convegno
conference: 9th Biology and Molecular Medicine PhD School Symposium (BeMM) (Roma)
book: Book of Abstract - ()
11573/954245 - 2018 -
Bax activation blocks self-renewal and induces apoptosis of human glioblastoma stem cells La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ACS CHEMICAL NEUROSCIENCE (Washington, D.C. : American Chemical Society) pp. 85-99 - issn: 1948-7193 - wos: WOS:000423016300010 (16) - scopus: 2-s2.0-85040673427 (18)
11573/1014226 - 2017 -
Chiral indolylarylsulfone non-nucleoside reverse transcriptase inhibitors as new potent and broad spectrum anti-HIV-1 agents Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Catalano, Myriam; Limatola, Cristina; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6528-6547 - issn: 0022-2623 - wos: WOS:000407656700004 (16) - scopus: 2-s2.0-85027261384 (17)
11573/1025425 - 2017 -
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities Pelliccia, Sveva; Coluccia, Antonio; La Regina, Giuseppe; Famiglini, Valeria; Masci, Domiziana; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 1091-1101 - issn: 1475-6366 - wos: WOS:000408991900004 (28) - scopus: 2-s2.0-85026861941 (28)
11573/1026343 - 2017 -
Computer-aided identification and lead optimization of dual murine double minute 2 and 4 binders: structure-activity relationship studies and pharmacological activity Pelliccia, Sveva; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8115-8130 - issn: 0022-2623 - wos: WOS:000413131400012 (13) - scopus: 2-s2.0-85031292289 (13)
11573/1033449 - 2017 -
Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors Passacantilli, Sara; Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Masci, Domiziana; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()
11573/1033450 - 2017 -
Inhibition of Dengue virus by novel inhibitors of RNA-dependent RNA polymerase and protease activities La Regina, Giuseppe; Famiglini, Valeria; Masci, Domiziana; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()
11573/1033456 - 2017 -
3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin La Regina, Giuseppe; Naccarato, Valentina; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: 10th Joint Meeting on Medicinal Chemistry (Dubrovnik, Croazia)
book: Book of Abstracts - ()
11573/1033457 - 2017 -
New pyrrole inhibitors of chronic myeloid leukemia cell growth Naccarato, Valentina; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()
11573/1033458 - 2017 -
Drug design and synthesis of new indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors Masci, Domiziana; La Regina, Giuseppe; Famiglini, Valeria; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()
11573/1033459 - 2017 -
New inhibitors of Dengue and Zika virus protease Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04f Poster
conference: XXVI Congresso Nazionale della Società Chimica Italiana (Paestum (SA))
book: Programma del XXVI Congresso Nazionale della Società Chimica Italiana - ()
11573/1033464 - 2017 -
Heterocyclic pharmacochemistry of new rhinovirus antiviral agents: a combined computational and experimental study Coluccia, Antonio; Rosetti, Alessia; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 528-541 - issn: 0223-5234 - wos: WOS:000414620000037 (8) - scopus: 2-s2.0-85030546760 (11)
11573/902826 - 2017 -
p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells Soriani, Alessandra; Borrelli, Cristiana; Molfetta, Rosa; Zingoni, Alessandra; Fionda, Cinzia; Abruzzese, Maria Pia; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; La Regina, Giuseppe; Silvestri, Romano; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela - 01a Articolo in rivista
paper: ONCOIMMUNOLOGY ([Abingdon]: Taylor & Francis) pp. e1264564-e1264564 - issn: 2162-402X - wos: WOS:000397069400020 (23) - scopus: 2-s2.0-85015270684 (24)
11573/935705 - 2017 -
Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules Di Cesare, Erica; Verrico, Annalisa; Miele, Andrea; Giubettini, Maria; Coluccia, Antonio; Famiglini, Valeria; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 19738-19759 - issn: 1949-2553 - wos: WOS:000396879200088 (14) - scopus: 2-s2.0-85015806343 (15)
11573/952050 - 2017 -
Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells Stirpe, Mariarita; Palermo, Vanessa; Bianchi, Michele Maria; Silvestri, Romano; Falcone, Claudio; Mazzoni, Cristina - 01a Articolo in rivista
paper: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (London: BioMed Central.) pp. - - issn: 1472-6882 - wos: WOS:000398770600001 (16) - scopus: 2-s2.0-85017244055 (20)
11573/954246 - 2017 -
3-Aroyl-1,4-diarylpyrroles inhibit chronic myeloid leukemia cell growth through an interaction with tubulin La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Naccarato, Valentina; Ortar, Giorgio; Mazzoccoli, Carmela; Nalli, Marianna; Silvestri, Romano - 01a Articolo in rivista
paper: ACS MEDICINAL CHEMISTRY LETTERS (USA: ACS Publications) pp. 521-526 - issn: 1948-5875 - wos: WOS:000401402900010 (6) - scopus: 2-s2.0-85018898332 (6)
11573/955362 - 2017 -
Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors Mollica, Adriano; Pelliccia, Sveva; Famiglini, Valeria; Stefanucci, Azzurra; Ragno, Rino; Patsilinakos, Alexandros; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 444-451 - issn: 1475-6366 - wos: WOS:000392591100034 (25) - scopus: 2-s2.0-85015583368 (25)
11573/955375 - 2017 -
N-Pyrrylarylsulfones with high therapeutic potential Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000398743500095 (7) - scopus: 2-s2.0-85015716668 (7)
11573/838741 - 2016 -
Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo Masuelli, Laura; Pantanella, Fabrizio; La Regina, Giuseppe; Benvenuto, Monica; Mattera, Rosanna; Di Stefano, Enrica; Silvestri, Romano; Schippa, Serena - 01a Articolo in rivista
paper: TUMOR BIOLOGY (S Karger AG:Allschwilerstrasse 10, CH-4009 Basel Switzerland:011 41 61 3061111, EMAIL: orders@karger.ch, INTERNET: http://www.karger.com, Fax: 011 41 61 3061234) pp. 3705-3717 - issn: 1010-4283 - wos: WOS:000374903500096 (41) - scopus: 2-s2.0-84944704386 (42)
11573/872535 - 2016 -
VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 453-462 - issn: 0223-5234 - wos: WOS:000375360800039 (5) - scopus: 2-s2.0-84962663541 (7)
11573/879604 - 2016 -
Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(III) complex in human cancer cell lines Portalone, Gustavo; Pelliccia, Sveva; Silvestri, Romano - 01a Articolo in rivista
paper: MEDCHEMCOMM (Cambridge : Royal Society of Chemistry, 2010-) pp. 1604-1616 - issn: 2040-2503 - wos: WOS:000381413300012 (12) - scopus: 2-s2.0-84982156083 (12)
11573/880563 - 2016 -
Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase Pennacchietti, Eugenia; Coluccia, Antonio; Silvestri, Romano; De Biase, Daniela - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 295-301 - issn: 1475-6366 - wos: WOS:000368719800014 (12) - scopus: 2-s2.0-84955443104 (13)
11573/887652 - 2016 -
New Inhibitors of Dengue Virus Replication Famiglini, Valeria; Pelliccia, Sveva; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV National Meeting on Medicinal Chemistry (Perugia)
book: Abstract eBook - ()
11573/887653 - 2016 -
New Inhibitors of indoleamine 2,3-dioxygenase 1: molecular modelling studies, synthesis and biological evaluation La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Passacantilli, Sara; Mazzoccoli, Carmela; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV National Meeting on Medicinal Chemistry (Perugia)
book: Abstract eBook - ()
11573/897502 - 2016 -
New inhibitors of indoleamine 2,3-dioxygenase 1: molecular modeling studies, synthesis, and biological evaluation Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Sabatino, Manuela; Patsilinakos, Alexandros; Ragno, Rino; Mazzoccoli, Carmela; Silvestri, Romano; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9760-9773 - issn: 0022-2623 - wos: WOS:000387737600010 (28) - scopus: 2-s2.0-84994853619 (30)
11573/907866 - 2016 -
Structure-based virtual screening to get new scaffold inhibitors of the Ser/Thr protein kinase PknB from Mycobacterium tuberculosis Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: LETTERS IN DRUG DESIGN & DISCOVERY (Bentham Science Publishers Ltd) pp. 1012-1018 - issn: 1570-1808 - wos: WOS:000389464700004 (4) - scopus: 2-s2.0-84995937420 (4)
11573/955391 - 2016 -
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: MOLECULES (Basel: MDPI
Berlin: Springer, 1996-) pp. - - issn: 1420-3049 - wos: WOS:000371895900041 (16) - scopus: 2-s2.0-84964558153 (18)
11573/1505230 - 2015 -
New frontiers in selective human MAO-B inhibitors Silvestri, Romano - 01g Articolo di rassegna (Review)
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington DC : ACS Publications) pp. 6717-6732 - issn: 1520-4804 - wos: WOS:000361254600001 (152) - scopus: 2-s2.0-84937240385 (162)
11573/663213 - 2015 -
New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2 Pelliccia, Sveva; La Regina, Giuseppe; Famiglini, Valeria; Coluccia, Antonio; Nencioni, Lucia; Palamara, Anna Teresa; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 497-506 - issn: 0223-5234 - wos: WOS:000348951900040 (21) - scopus: 2-s2.0-84914680268 (24)
11573/764095 - 2015 -
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents La Regina, Giuseppe; Passacantilli, Sara; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2135-2148 - issn: 0022-2623 - wos: WOS:000351186500007 (29) - scopus: 2-s2.0-84924664711 (30)
11573/764098 - 2015 -
Pharmacological folding chaperones act as allosteric ligands of Frizzled4 La Regina, Giuseppe; Passacantilli, Sara; Silvestri, Romano - 01a Articolo in rivista
paper: NATURE CHEMICAL BIOLOGY (NATURE PUBLISHING GROUP, 75 VARICK STREET, 9TH FLOOR, NEW YORK, USA, NY, 10013-1917) pp. 280-286 - issn: 1552-4450 - wos: WOS:000351666500011 (29) - scopus: 2-s2.0-84930247167 (29)
11573/780891 - 2015 -
Kinetic characterization of 4,4'-biphenylsulfonamides as selective non-zinc binding MMP inhibitors La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (Taylor & Francis Limited:Rankine Road, Basingstoke RG24 8PR United Kingdom:011 44 1256 813035, EMAIL: madeline.sims@tandf.co.uk, info@tandf.co.uk, INTERNET: http://www.tandf.co.uk, Fax: 011 44 1256 330245) pp. 947-954 - issn: 1475-6366 - wos: WOS:000369915500012 (12) - scopus: 2-s2.0-84945914800 (13)
11573/845349 - 2015 -
Discovery of 1,1'-biiphenyl-4-sulfonamides as a new class of potent and selective carbonic anhydrase XIV inhibitors La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Monti, Ludovica; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8564-8572 - issn: 0022-2623 - wos: WOS:000364796100017 (33) - scopus: 2-s2.0-84947266183 (34)
11573/845838 - 2015 -
Endogenous vs exogenous allosteric modulators in GPCRs: a dispute for shuttling CB1 among different membrane microenvironments La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: SCIENTIFIC REPORTS (London : Nature Publishing Group) pp. - - issn: 2045-2322 - wos: WOS:000363036200001 (34) - scopus: 2-s2.0-84945193701 (35)
11573/845844 - 2015 -
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer La Regina, Giuseppe; Verrico, Annalisa; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Mazzoccoli, Carmela; Miele, Andrea; Monti, Ludovica; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Ricci, Biancamaria; Soriani, Alessandra; Santoni, Angela; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5789-5807 - issn: 0022-2623 - wos: WOS:000359683700008 (46) - scopus: 2-s2.0-84939138196 (46)
11573/854568 - 2015 -
Poster: "In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation” Danovska, Svetlana; Licursi, Valerio; Rinaldi, Teresa; Proietto, Marco; Pippa, Simone; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 04a Atto di comunicazione a congresso
conference: ICYGMB - Internationa Congress of Yeast Genetics and Molecular Biology (Levico Terme (TN))
book: Abstracts of the 27th International Conference on Yeast Genetics and Molecular Biology - ()
11573/868746 - 2015 -
New indole tubulin assembly inhibitors with stable arrest of mitotic progression, enhanced stimulation of natural killer cell cytotoxic activity and repression of Hedgehog-dependent cancer La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Spanish-Italian Medicinal Chemistry Congress (Barcellona, Spagna)
book: SIMCC2015 - ()
11573/868759 - 2015 -
Synthesis of New Indoles with Potent Tubulin Polymerization Inhibiting Activity Including Hedgehog-Dependent Cancer and Enhanced Stimulation of NK Cell Cytotoxic Activity Passacantilli, Sara; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()
11573/868767 - 2015 -
New Pyrazolecarboxamides a s Anti-HCV Agents via Targeting Cyclooxygenase-2 Pelliccia, Sveva; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()
11573/868769 - 2015 -
Drug Design and Synthesis of New Indolylarylsulfones as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII National Meeting on Medicinal Chemistry - Nuove Prospettive in Chimica Farmaceutica 9° Meeting (Fisciano)
book: Abstract eBook - ()
11573/872560 - 2015 -
In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: VIROLOGY JOURNAL (London : Biomed Central) pp. - - issn: 1743-422X - wos: WOS:000357775400001 (24) - scopus: 2-s2.0-84937203434 (25)
11573/955444 - 2015 -
Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells Silvestri, Romano - 01a Articolo in rivista
paper: CANCER BIOLOGY & THERAPY (Georgetown, TX : Landes Bioscience) pp. 1820-1829 - issn: 1555-8576 - wos: WOS:000369916100016 (6) - scopus: 2-s2.0-84954526267 (7)
11573/955459 - 2015 -
Distinct temporal fingerprint for cyclic adenosine monophosphate (cAMP) signaling of Indole-2-carboxamides as allosteric modulators of the cannabinoid receptors Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5979-5988 - issn: 0022-2623 - wos: WOS:000359683700021 (24) - scopus: 2-s2.0-84939169250 (24)
11573/538415 - 2014 -
An High-Throughput In Vivo Screening System to Select H3K4-Specific Histone Demethylase Inhibitors Proietto, Marco; Bufalieri, Francesca; Alagia, Angela Alessandra; Danovska, Svetlana; Rinaldi, Teresa; Famiglini, Valeria; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano; Negri, Rodolfo - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. e86002-e86002 - issn: 1932-6203 - wos: WOS:000330570000022 (13) - scopus: 2-s2.0-84900435770 (14)
11573/558611 - 2014 -
New, simple and high-yielding synthesis of 2,9-dihydro-1H-pyrido[3,4-b]indol-1-ones La Regina, Giuseppe; Famiglini, Valeria; Passacantilli, Sara; Silvestri, Romano - 01a Articolo in rivista
paper: SYNTHESIS (Stuttgart : Thieme Verlag) pp. 2093-2097 - issn: 0039-7881 - wos: WOS:000340874800016 (7) - scopus: 2-s2.0-84904763883 (10)
11573/559735 - 2014 -
New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 101-111 - issn: 0223-5234 - wos: WOS:000337985400009 (19) - scopus: 2-s2.0-84899103627 (21)
11573/649699 - 2014 -
New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Pelliccia, Sveva; Passacantilli, Sara; Miele, Andrea; Nalli, Marianna; Alfonsi, Romina; Di Marcotullio, Lucia; Gulino, Alberto; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6531-6552 - issn: 0022-2623 - wos: WOS:000340445900020 (63) - scopus: 2-s2.0-84906094556 (68)
11573/671843 - 2014 -
Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 9945-9957 - issn: 0022-2623 - wos: WOS:000346321200017 (39) - scopus: 2-s2.0-84918566396 (42)
11573/671846 - 2014 -
Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4598-4605 - issn: 0022-2623 - wos: WOS:000337336600014 (26) - scopus: 2-s2.0-84902438483 (26)
11573/675361 - 2014 -
3-Aroyl-1-arylpyrroles as new anticancer agents La Regina, Giuseppe; Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXV Congresso Nazionale della Società Chimica Italiana (Arcavacata di Rende (CS))
book: Atti del Congresso - ()
11573/675406 - 2014 -
3-Aroyl-1-arylpyrroles: a new class of potent inhibitors of tubulin polymerization La Regina, Giuseppe; Coluccia, Antonio; Passacantilli, Sara; Famiglini, Valeria; Pelliccia, Sveva; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Fifth European Workshop in Drug Synthesis (Siena (SI))
book: Fifth European Workshop in Drug Synthesis - ()
11573/675447 - 2014 -
New modulator of the tumoural immune escape via Indoleamin 2,3-dioxygenase (IDO) inhibition. Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXV Congresso Nazionale della Società Chimica Italiana (Arcavacata di Rende)
book: Atti del Congresso - ()
11573/675451 - 2014 -
New Indolylarylsulfones as Potent and Broad Spectrum HIV‐1 Non-Nucleoside Reverse Transcriptase Inhibitors. II. Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()
11573/675453 - 2014 -
Selective Synthesis of 2,9-Dihydro-1H-Pyrido[3,4-b]indol-1-ones. Passacantilli, Sara; La Regina, Giuseppe; Famiglini, Valeria; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()
11573/675489 - 2014 -
New 1-Phenyl‐5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides Inhibit Hepatitis C Virus Replication and Suppress the Expression of Cyclooxygenase-2. La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica - VIII Edizione del Meeting (Parma)
book: Book degli Abstracts - ()
11573/675493 - 2014 -
New Indolylarylsulfones as Potent and Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: International Conference on Antiviral Research (Raleigh, USA)
book: Program and Abstracts - ()
11573/675496 - 2014 -
New 1-Phenyl-5-(1H-Pyrrol-1-Yl)-1H-Pyrazole-3-Carboxamides Inhibit Hepatitis C Virus Replication and Suppress the Expression of Cyclooxygenase-2. La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 27th International Conference on Antiviral Research (Raleigh, USA)
book: Program and Abstracts - ()
11573/509896 - 2013 -
Toward Highly Potent Cancer Agents by Modulating the C-2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors La Regina, Giuseppe; Di Cesare, Erica; Coluccia, Antonio; Piscitelli, Francesco; Famiglini, Valeria; Nalli, Marianna; Pelliccia, Sveva; Soriani, Alessandra; Iannitto, Maria Luisa; Santoni, Angela; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 123-149 - issn: 0022-2623 - wos: WOS:000313221600012 (108) - scopus: 2-s2.0-84872352365 (105)
11573/541254 - 2013 -
Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 10066-10078 - issn: 0022-2623 - wos: WOS:000329331600018 (27) - scopus: 2-s2.0-84891341466 (33)
11573/546082 - 2013 -
Arylsulfone-based HIV-1 non-nucleoside reverse transcriptase inhibitors Famiglini, Valeria; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: FUTURE MEDICINAL CHEMISTRY (London : Future Science, 2009-.) pp. 2141-2156 - issn: 1756-8919 - wos: WOS:000327222400008 (16) - scopus: 2-s2.0-84889578221 (17)
11573/547286 - 2013 -
Highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors. La Regina, Giuseppe; Coluccia, Antonio; Famiglini, Valeria; Nalli, Marianna; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()
11573/547287 - 2013 -
A new, simple and high yielding synthesis of 2,9-dihydro-1H-pyrido[3,4-b]indol-1-ones. La Regina, Giuseppe; Famiglini, Valeria; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()
11573/547288 - 2013 -
New indolylarylsulfones as potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors. Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()
11573/547290 - 2013 -
Drug design and synthesis of GSK-3β inhibitors. Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()
11573/555492 - 2013 -
New prospects for vinblastine analogues as anticancer agents. Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 625-627 - issn: 0022-2623 - wos: WOS:000315182100002 (38) - scopus: 2-s2.0-84873886062 (36)
11573/555507 - 2013 -
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus. Gatti, Valerio; Silvestri, Romano; Coluccia, Antonio - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH ([Amsterdam]; [New York]: Elsevier/North-Holland, [c1981]-) pp. 12-18 - issn: 0166-3542 - wos: WOS:000318466200003 (71) - scopus: 2-s2.0-84874632357 (81)
11573/555510 - 2013 -
Exploring (4-substituted-thiazol-2-yl)hydrazine derivatives of 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors. Chimenti, Paola; Silvestri, Romano; Secci, Daniela - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 221-227 - issn: 0223-5234 - wos: WOS:000323628500024 (23) - scopus: 2-s2.0-84879467536 (23)
11573/675503 - 2013 -
Computational studies of colchicine site compounds. Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry (Roma)
book: Abstract Book - ()
11573/771841 - 2013 -
D,L peptides as strong inhibitors of HIV-1 GP120. Punzi, Pasqualina; Morosetti, Stefano; Silvestri, Romano; Scipioni, Anita - 04a Atto di comunicazione a congresso
conference: XXII National Meeting on Medicinal Chemistry NMMC 2013 (Roma)
book: XXII National Meeting on Medicinal Chemistry NMMC 2013 - ()
11573/461861 - 2012 -
New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Famiglini, Valeria; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6634-6638 - issn: 0022-2623 - wos: WOS:000306764600035 (45) - scopus: 2-s2.0-84864247649 (53)
11573/482220 - 2012 -
A new allosteric inhibitor of the hepatitis C virus NS5B polymerase is effective on HCV replication in infected cell culture system. Anticoli, Simona; Piscitelli, Francesco; Silvestri, Romano; Nencioni, Lucia; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
conference: 11th NATIONAL CONGRESS OF THE ITALIAN SOCIETY FOR VIROLOGY (ORVIETO (TR)
, Italy)
11573/483800 - 2012 -
Apple Can Act as Anti-Aging on Yeast Cells Palermo, Vanessa; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 01a Articolo in rivista
paper: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (London: Hindawi
AUSTIN, USA, TX: LANDES BIOSCIENCE) pp. 1-8 - issn: 1942-0900 - wos: WOS:000308498000001 (25) - scopus: 2-s2.0-84867365062 (25)
11573/501381 - 2012 -
New Indolylarylsulfones as Potent and Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors Famiglini, Valeria; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 12° Sigma Aldrich Young Chemists Symposium (Riccione)
book: Abstracts - ()
11573/501390 - 2012 -
New 2-Heterocyclil-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 12° Sigma Aldrich Young Chemists Symposium (Riccione)
book: Abstracts - ()
11573/501679 - 2012 -
First venting while heating microwave-assisted synthesis of 3-arylthioindoles as potent Inhibitors of tubulin polymerization. Famiglini, Valeria; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Meeting Nuove Prospettive in Chimica Farmaceutica 6 (Riccione)
book: Abstracts - ()
11573/501681 - 2012 -
Computer aided drug design approach in the development of PKnB inhibitors as potential antimycobacterial agents. Coluccia, Antonio; La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Meeting Nuove Prospettive in Chimica Farmaceutica 6 (Riccione)
book: Abstracts - ()
11573/502138 - 2012 -
Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid CB1 Receptor Piscitelli, Francesco; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5627-5631 - issn: 0022-2623 - wos: WOS:000305356400058 (53) - scopus: 2-s2.0-84862272370 (53)
11573/502189 - 2012 -
Venting-while-heating microwave-assisted synthesis of 3-arylthioindoles La Regina, Giuseppe; Gatti, Valerio; Famiglini, Valeria; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: ACS COMBINATORIAL SCIENCE (Washington, DC : American Chemical Society) pp. 258-262 - issn: 2156-8952 - wos: WOS:000303076400003 (35) - scopus: 2-s2.0-84859727783 (53)
11573/555514 - 2012 -
De novo computer-aided design of novel antiviral agents. Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: DRUG DISCOVERY TODAY (Elsevier Science Limited Trends Journals:PO Box 331, Haywards Heath RH16 3FG United Kingdom:011 44 1444 475651, EMAIL: ct.subs@rbi.co.uk, Fax: 011 44 1444 445423) pp. 213-218 - issn: 1359-6446 - wos: (0) - scopus: 2-s2.0-84873076621 (1)
11573/681651 - 2012 -
The tubulin colchicine domain: a molecular modelling perspective. Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: CHEMMEDCHEM (Weinheim : Wiley-VCH-Verl..) pp. 33-42 - issn: 1860-7179 - wos: WOS:000298549100003 (123) - scopus: 2-s2.0-84555195099 (126)
11573/1026412 - 2011 -
Open vessel and cooling while heating microwave-assisted synthesis of pyridinyl N-aryl hydrazones La Regina, Giuseppe; Gatti, Valerio; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: ACS COMBINATORIAL SCIENCE (Washington, DC : American Chemical Society) pp. 2-6 - issn: 2156-8952 - wos: WOS:000288062600001 (19) - scopus: 2-s2.0-78651432876 (21)
11573/355392 - 2011 -
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors. New cyclic substituents at the Indole-2-carboxamide La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04d Abstract in atti di convegno
conference: The 24th International Meeting on Antiviral Research (Sofia; Bulgaria)
book: Abstracts - ()
11573/395350 - 2011 -
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. Piscitelli, Francesco; La Regina, Giuseppe; Gatti, Valerio; Silvestri, Romano - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 5641-5653 - issn: 0223-5234 - wos: WOS:000298120500043 (13) - scopus: 2-s2.0-80054960004 (15)
11573/396005 - 2011 -
Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. New Cyclic Substituents at the Indole-2-carboxamide. Coluccia, Antonio; La Regina, Giuseppe; Gatti, Valerio; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV Congresso Nazionale della Società Chimica Italiana (Lecce)
book: Atti del Congresso - ()
11573/396013 - 2011 -
1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. Piscitelli, Francesco; La Regina, Giuseppe; Gatti, Valerio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIV Congresso Nazionale della Società Chimica Italiana (Lecce)
book: Atti del Congresso - ()
11573/502195 - 2011 -
Drug-induced inhibition of tubulin polymerization induces mitochondrion-mediated apoptosis in yeast Palermo, Vanessa; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 01a Articolo in rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3208-3209 - issn: 1538-4101 - wos: WOS:000294954400034 (8) - scopus: 2-s2.0-80052908186 (8)
11573/502211 - 2011 -
Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 107-118 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-84861534913 (8)
11573/502225 - 2011 -
Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Gatti, Valerio; Soriani, Alessandra; Iannitto, Maria Luisa; Santoni, Angela; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 8394-8406 - issn: 0022-2623 - wos: WOS:000297946300016 (68) - scopus: 2-s2.0-84055211830 (71)
11573/502235 - 2011 -
Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: New Cyclic Substituents at the Indole-2-carboxamide. La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Gatti, Valerio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1587-1598 - issn: 0022-2623 - wos: WOS:000288400700005 (110) - scopus: 2-s2.0-79952792724 (133)
11573/226813 - 2010 -
Synthesis, in vivo pharmacological evaluation and pharmacokinetic studies of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide cannabinoid receptor ligands. Gatti, Valerio; La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Nuove Prospettive in Chimica Farmaceutica, IV Meeting – Workshop (Santa Margherita di Pula (CA))
book: Abstracts - ()
11573/227389 - 2010 -
Radiosynthesis and in vivo evaluation of [11C]-labelled pyrrole-2-carboxamide derivates as novel radioligands for PET imaging of monoamine oxidase A La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: NUCLEAR MEDICINE AND BIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 459-467 - issn: 0969-8051 - wos: WOS:000277701900010 (10) - scopus: 2-s2.0-77952549176 (13)
11573/355390 - 2010 -
Molecular dynamic studies of arylthioindoles, potent inhibitors of tubulin polymerization Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX national Meeting on Medicinal Chemistry (Abano Terme, Padova)
book: Book of Abstracts - ()
11573/355391 - 2010 -
Indolylarylsulfones bearing natural and unnatural amino acids as inhibitors of HIV-1 reverse transcriptase and Coxsackie B4 virus. Gatti, Valerio; La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Antiviral Congress (Amsterdam (NL))
book: Abstracts - ()
11573/355731 - 2010 -
Discovery of a novel hcv helicase inhibitors by a de novo design approach. Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX national Meeting on Medicinal Chemistry (Abano Terme, Padova)
book: Book of Abtracts - ()
11573/362000 - 2010 -
Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Silvestri, Romano; La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 5878-5886 - issn: 0223-5234 - wos: WOS:000285485000040 (9) - scopus: 2-s2.0-78649319952 (9)
11573/362016 - 2010 -
Enantioselective HPLC combined with spectroscopic methods: A valid strategy to determine the absolute configuration of potential beta-secretase inhibitors La Regina, Giuseppe; Pierini, Marco; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: TALANTA (-Oxford, United Kingdom: Elsevier Science Limited
Oxford: Pergamon, 1958-) pp. 1306-1312 - issn: 0039-9140 - wos: WOS:000282480500032 (11) - scopus: 2-s2.0-77956182621 (11)
11573/366769 - 2010 -
Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 213-237 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-77956900680 (57)
11573/396161 - 2010 -
New N-Alkyl 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as potent cannabinoid receptor ligands. La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XX National Meetings on Medicinal Chemistry (Abano Terme - Padova)
book: Book of Abstracts - ()
11573/412070 - 2010 -
S. cerevisiae as a model for the study of new therapeutic molecules Palermo, Vanessa; Silvestri, Romano; La Regina, Giuseppe; Falcone, Claudio; Mazzoni, Cristina - 04c Atto di convegno in rivista
paper: JOURNAL OF BIOTECHNOLOGY (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 412-412 - issn: 0168-1656 - wos: WOS:000288873401735 (0) - scopus: (0)
conference: 14th International Biotechnology Symposium and Exhibition (Rimini Italy)
11573/502271 - 2010 -
Arylthioindoles: Promising compounds against cancer cell proliferation. Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ONCOLOGY LETTERS (Athens Greece: Spandidos Publications Ltd.) pp. 109-112 - issn: 1792-1074 - wos: WOS:000284562300020 (9) - scopus: 2-s2.0-77955753209 (9)
11573/71306 - 2010 -
A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds Silvestri, Romano - 01a Articolo in rivista
paper: PLOS ONE (San Francisco, CA : Public Library of Science) pp. 1-13 - issn: 1932-6203 - wos: WOS:000279924500007 (14) - scopus: 2-s2.0-77955407826 (16)
11573/71630 - 2010 -
Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs) exert their anti-proliferative activity by interfering with Akt-mTOR signaling and bax:bcl-2 ratio modulation in cells from chronic myeloid leukemic patients Silvestri, Romano - 01a Articolo in rivista
paper: CANCER SCIENCE (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 991-1000 - issn: 1347-9032 - wos: WOS:000275728200024 (6) - scopus: 2-s2.0-77957282697 (7)
11573/225640 - 2009 -
Molecular Modeling applications studies on the Indolyl Aryl Sulphones (IASs) as HIV-1 Non-Nucleotidic Reverse transcriptase inhibitors. Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()
11573/225842 - 2009 -
Drug Design of New NS3/4A HCV Serine Protease Inhibitors. Structure-Based and Ligand-Based Approaches. Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()
11573/225843 - 2009 -
Indolylarylsulfones Bearing Natural and Unnatural Amino Acids as Potent HIV-1 NNRTIs. Piscitelli, Francesco; La Regina, Giuseppe; Gatti, Valerio; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()
11573/225846 - 2009 -
Design and synthesis of novel metalloproteinases inhibitors La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()
11573/226394 - 2009 -
Indolylarylsulfones Bearing Natural and Unnatural Amino Acids are Potent HIV-1 Reverse Transcriptase and Coxsackie B4 Virus Non-Nucleoside Inhibitors. Piscitelli, Francesco; Coluccia, Antonio; La Regina, Giuseppe; La Torre, Filippo; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: The 22nd International Meeting on Antiviral Research (Miami Beach, Florida, USA)
book: Abstracts - ()
11573/226395 - 2009 -
Arylthioindole Bioisosteres as Potent Tubulin Polymerization and MCF-7 Cell Growth Inhibitors Gatti, Valerio; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()
11573/226397 - 2009 -
New Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as High Affinity hCB1 Ligands La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXIII Congresso Nazionale della Società Chimica Italiana (Sorrento (NA))
book: Atti del Congresso - ()
11573/226478 - 2009 -
Molecular Modeling Studies of Arylthioindoles and Related Bioisosteres, Potent Inhibitors of Tubulin Polymerization. La Regina, Giuseppe; Coluccia, Antonio; Gatti, Valerio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: VI European Workshop in Drug Design (Certosa di Pontignano)
book: Abstracts - ()
11573/226692 - 2009 -
Polymerization and MCF-7 Cell Growth Inhibitors. New Bioisosteres at the Sulfur Bridging Group. Gatti, Valerio; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()
11573/358688 - 2009 -
New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Gatti, Valerio; Palermo, Vanessa; Mazzoni, Cristina; Falcone, Claudio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 7512-7527 - issn: 0022-2623 - wos: WOS:000272338000020 (86) - scopus: 2-s2.0-72249084715 (92)
11573/359833 - 2009 -
Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile Silvestri, Romano; La Regina, Giuseppe; Piscitelli, Francesco; Gatti, Valerio - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 5549-5564 - issn: 0968-0896 - wos: WOS:000268099700023 (14) - scopus: 2-s2.0-67849084545 (13)
11573/362045 - 2009 -
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex. La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL RESEARCH ([Amsterdam]; [New York]: Elsevier/North-Holland, [c1981]-) pp. 47-55 - issn: 0166-3542 - wos: WOS:000262589900006 (15) - scopus: 2-s2.0-57149112301 (16)
11573/364409 - 2009 -
Study of the effects of a new pyrazolecarboxamide: Changes in mitochondria and induction of apoptosis Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (Applied Science Publishers:Ripple Road, Barking Essex United Kingdom) pp. 1890-1898 - issn: 1357-2725 - wos: WOS:000270351100016 (15) - scopus: 2-s2.0-68949092046 (18)
11573/364587 - 2009 -
Indolyl Aryl Sulfones bearing Natural and Unnatural Aminoacids. Discovery of Potent Inhibitors of both HIV-1 Non-Nucleoside Wild Type and Resistant Mutant Strains Reverse Transcriptase, and Coxsackie B4 Virus. Piscitelli, Francesco; Coluccia, Antonio; La Regina, Giuseppe; La Torre, Filippo; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1922-1934 - issn: 0022-2623 - wos: WOS:000264835800014 (54) - scopus: 2-s2.0-64549155260 (58)
11573/396023 - 2009 -
Radiosynthesis and in vivo evaluation of [11C]-(R)-N-(1-cyclohexylethyl-N-methyl-1H-pyrrole-2-carboxamide. La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 18th International Symposium on Radiopharmaceutical Sciences (Edmonton, Canada)
book: Abstracts of Presentations - ()
11573/501687 - 2009 -
Pirazolocarbossiamidi e morte cellulare: una nuova arma per la chemioterapia. Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: La morte della cellula: implicazioni fisio-patologiche e terapeutiche (Firenze)
book: Atti - ()
11573/502676 - 2009 -
Synthetic Strategies of Non-Peptidic beta-Secretase (BACE1) Inhibitors. La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF HETEROCYCLIC CHEMISTRY (Hetero Corporation:PO Box 170:Provo, UT 84603:(801)400-7373, EMAIL: jhetchem@yahoo.com, Fax: (801)356-7373) pp. 10-17 - issn: 0022-152X - wos: WOS:000264349600002 (6) - scopus: 2-s2.0-61849126868 (9)
11573/71628 - 2009 -
Boom in the development of non-peptidic beta-secretase (BACE1) inhibitors for the treatment of Alzheimer's disease Silvestri, Romano - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 295-338 - issn: 0198-6325 - wos: WOS:000263510600003 (107) - scopus: 2-s2.0-62249167406 (113)
11573/224408 - 2008 -
Docking and Molecular Dynamics Studies of Arylthioindoles. La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XIX National Meeting on Medicinal Chemistry (Verona, Italy)
book: Book of Abstracts - ()
11573/224410 - 2008 -
Progress in the development of arylthioindoles, potent inhibitors of tubulin polymerization and MCF-7 cell growth. La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XIX National Meeting on Medicinal Chemistry (Verona, Italy)
book: Book of Abstracts - ()
11573/362035 - 2008 -
Synthesis, Cannabinoid Receptor Affinity and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. Silvestri, Romano; La Regina, Giuseppe; Piscitelli, Francesco - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1560-1576 - issn: 0022-2623 - wos: WOS:000254209800005 (65) - scopus: 2-s2.0-41149151354 (69)
11573/364131 - 2008 -
1-[(3-Aryloxy-3-aryl)propyl]-2H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies La Regina, Giuseppe; D'auria, Felicia Diodata; Piscitelli, Francesco; Nencioni, Lucia; Artico, Marino; Palamara, Anna Teresa; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3841-3855 - issn: 0022-2623 - wos: WOS:000257391000019 (31) - scopus: 2-s2.0-46849105237 (32)
11573/364205 - 2008 -
An improved synthesis of ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 204-208 - issn: 0030-4948 - wos: WOS:000255310900004 (4) - scopus: 2-s2.0-44149117529 (5)
11573/364212 - 2008 -
Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B. La Regina, Giuseppe; Silvestri, Romano; Gatti, Valerio; Agostinelli, Enzo - 01a Articolo in rivista
paper: BIOORGANIC & MEDICINAL CHEMISTRY (Oxford: Pergamon, 1993-) pp. 9729-9740 - issn: 0968-0896 - wos: WOS:000260758200011 (35) - scopus: (0)
11573/396351 - 2008 -
Progress in the development of arylthioindoles, potent inhibitors of tubulin polymerization and MCF-7 cell growth. La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()
11573/396552 - 2008 -
Docking and Molecular Dynamics Studies of Arylthioindoles. La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()
11573/396610 - 2008 -
Indolyl Aryl Sulfones with aminoacid units as potent HIV-1 NNRTIs. Piscitelli, Francesco; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Strutture Eteroclicliche nella Ricerca Farmaceutica (Palermo)
book: Atti - ()
11573/144595 - 2007 -
Arylthioindole Inhibitors of Tubulin Polymerization. 3. Biological Evaluation, Structure−Activity Relationships and Molecular Modeling Studies La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2865-2874 - issn: 0022-2623 - wos: WOS:000247033900011 (170) - scopus: 2-s2.0-34250869030 (173)
11573/234427 - 2007 -
Arylthioindoles: Docking and Molecular Dynamics Studies. La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()
11573/237475 - 2007 -
Induction of Apoptosis in Human Tumor Cells by a New Pyrazolcarboxamide La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena, Italy)
book: Program and Abstracts - ()
11573/237477 - 2007 -
Arylthioindoles: Design, Synthesis and Biological Activity La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti, Italy)
book: Atti del Convegno - ()
11573/237794 - 2007 -
New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. La Regina, Giuseppe; Silvestri, Romano; Artico, Marino; Agostinelli, Enzo - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 922-931 - issn: 0022-2623 - wos: WOS:000244530400004 (115) - scopus: 2-s2.0-33847770688 (116)
11573/237900 - 2007 -
Effects of a new arylthioindole on HeLa cell metabolism La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena)
book: Program and Abstracts - ()
11573/238314 - 2007 -
Synthesis of Indol Aryl Sulfones bearing Natural and Unnatural Aminoacids as Potent HIV-1 Non-Nucleoside Reverse Transcriptase. Piscitelli, Francesco; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()
11573/240105 - 2007 -
PYRROLO[1,2-b][1,2,5]BENZOTHIADIAZEPINES (PBTDs) induce apoptosis in K562 cells. Silvestri, Romano; Di Renzo, Livia Maria; La Regina, Giuseppe - 01a Articolo in rivista
paper: BMC CANCER (BIOMED CENTRAL LTD, MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB) pp. 207- - issn: 1471-2407 - wos: WOS:000252786900001 (7) - scopus: 2-s2.0-38949085858 (9)
11573/358071 - 2007 -
Indolyl Aryl Sulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Role of Two Halogen Atoms at the Indole Ring in Developing New Analogues with Improved Antiviral Activity La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5034-5038 - issn: 0022-2623 - wos: WOS:000249871300022 (50) - scopus: 2-s2.0-34948862163 (55)
11573/363492 - 2007 -
Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3-D QSAR studies. Ragno, Rino; Coluccia, Antonio; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: EXPERT OPINION ON DRUG DISCOVERY (--London United Kingdom:Informa Healthcare
-London : Informa Healthcare, 2006-.) pp. 87-114 - issn: 1746-0441 - wos: WOS:000207616400006 (7) - scopus: 2-s2.0-34447527787 (7)
11573/395984 - 2007 -
Indolilarilsolfoni, potenti e selettivi agenti anti-HIV La Regina, Giuseppe; Piscitelli, Francesco; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 7° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) (Riccione (RN))
book: 7° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) - ()
11573/396620 - 2007 -
Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-Pyrazole-3-Carboxamides as Potent Pyrrole Bioisosteres of Rimonabant and SR144528. Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Frontiers in CNS and Oncology Medicinal Chemistry (Siena)
book: Program and Abstracts - ()
11573/396664 - 2007 -
Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides, as Potent Pyrrole Bioisosteres of Rimonabant and SR144528. Piscitelli, Francesco; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVIII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Chieti)
book: Atti del Convegno - ()
11573/502809 - 2007 -
Arylcarbonlyindoles: Antimitotic Agents and Potent Inhibitors of Tubulin Polymerization. La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: American Society for Cell Biology (ASCB) 47th Annual Meeting (Washington, USA)
book: Abstracts - ()
11573/72148 - 2007 -
Indole, a Core Nucleus for Potent Inhibitors of Tubulin Polymerization. Silvestri, Romano - 01a Articolo in rivista
paper: MEDICINAL RESEARCH REVIEWS (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 209-238 - issn: 0198-6325 - wos: WOS:000244254500003 (323) - scopus: 2-s2.0-33847172794 (323)
11573/144591 - 2006 -
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carbxamide. La Regina, Giuseppe; Ragno, Rino; Coluccia, Antonio; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: ANTIVIRAL CHEMISTRY & CHEMOTHERAPY (International Medical Press:2-4 Idol Lane, London EC3R 5DD United Kingdom:011 44 207 3980700, EMAIL: imp@intmedpress.com, INTERNET: http://www.intmedpress.com, Fax: 011 44 207 3980701) pp. 59-77 - issn: 0956-3202 - wos: (0) - scopus: 2-s2.0-33745100897 (40)
11573/203690 - 2006 -
Synthesis and evaluation of novel potential HCV helicase ihibitors. Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 9th International Conference on Antiviral Research (San Juan, Porto Rico)
book: Abtracts - ()
11573/233924 - 2006 -
Synthesis of Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): New Agents for the Treatment of Chronic Myelogenus Leukemia (CML). La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Atti del Congresso - ()
11573/238618 - 2006 -
Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs): A New Class of Agents with High Apoptotic Activity in Chronic Myelogenous Leukemia K562 Cells and in Cells from Patients at Onset and Who Were Imatinib-Resistant. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; La Torre, Filippo - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 5840-5844 - issn: 0022-2623 - wos: WOS:000240495600019 (61) - scopus: 2-s2.0-33748877961 (62)
11573/359248 - 2006 -
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide Ragno, Rino; Coluccia, Antonio; La Regina, Giuseppe; Piscitelli, Francesco; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3172-3184 - issn: 0022-2623 - wos: WOS:000237832400018 (154) - scopus: 2-s2.0-33744831188 (160)
11573/361589 - 2006 -
New Arylthioindoles: Potent Inhibitors of Tubulin Polymerization. 2. Structure-Activity Relationships and Molecular Modeling Studies. La Regina, Giuseppe; Coluccia, Antonio; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 947-954 - issn: 0022-2623 - wos: WOS:000235826300014 (340) - scopus: 2-s2.0-32344432249 (347)
11573/396469 - 2006 -
Arylthioindoles, Potent Inhibitors of Tubulin Polymerization: Structure-Activity Relationships and Molecular Modeling Studies. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()
11573/396668 - 2006 -
Structure-Based and 3-D QSAR Drug Design of New Indolyl Aryl Sulfones. Coluccia, Antonio; Ragno, Rino; La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()
11573/396674 - 2006 -
New Indolyl Aryl Sulfones (IASs) as potent anti-HIV agents. Piscitelli, Francesco; La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XXII Congresso Nazionale della Società Chimica Italiana (Firenze)
book: Atti del Congresso - ()
11573/53434 - 2006 -
Improved 3-D QSAR Model on Indolyl Aryl Sulfones: Design of potent anti-HIV-1 active against both wild type and mutant form of RT. Coluccia, Antonio; Ragno, Rino; La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: The 16th European Symposium on Quantitative Structure-Activity Relationships & Molecular Modelling (Civitavecchia)
11573/57584 - 2006 -
Indole nucleus as a selected pharmacophore for the design of novel highly anti-HIV RT inhibitors and also capable to inhibit tumor cell replication. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Piscitelli, Francesco; Coluccia, Antonio; Ragno, Rino - 04a Atto di comunicazione a congresso
conference: Hosts, Symbionts and Parasites: Molecular and Pharmacological Approaches (Roma)
book: Abstracts - ()
11573/57661 - 2006 -
Ariltioindoli, potenti inibitori della polimerizzazione della tubulina La Regina, Giuseppe; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 6° Sigma Aldrich Young Chemists Symposium (S.A.Y.C.S.) (Riccione (RN))
book: 6° Sigma Aldrich Young Chemists Symposium - ()
11573/71187 - 2006 -
Direct HPLC enantioseparation of chiral aptazepine derivatives on coated and bonded polysaccharide-based chiral stationery phases. Orlando, Viviana; Silvestri, Romano; La Torre, Filippo - 01a Articolo in rivista
paper: CHIRALITY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 621-632 - issn: 0899-0042 - wos: WOS:000239204000008 (29) - scopus: 2-s2.0-33750071730 (32)
11573/72150 - 2006 -
Current state-of-the-art in preclinical and clinical development of novel non-nucleoside HIV-1 reverse transcriptase inhibitors Silvestri, Romano - 01a Articolo in rivista
paper: EXPERT OPINION ON THERAPEUTIC PATENTS (--London United Kingdom:Informa Healthcare
-London, United Kingdom: Ashley Publications Limited) pp. 939-962 - issn: 1354-3776 - wos: WOS:000202984700004 (11) - scopus: 2-s2.0-34247179717 (11)
11573/138978 - 2005 -
Comparative study between the polysaccharidebased Chiralcel OJ and Chiralcel OD CSPs in chromatographic enantioseparation of imidazole analogues of Fluoxetine and Miconazole. La Torre, Filippo; La Regina, Giuseppe; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF SEPARATION SCIENCE (WILEY-V C H VERLAG GMBH, PO BOX 10 11 61, WEINHEIM, GERMANY, D-69451) pp. 627-634 - issn: 1615-9314 - wos: WOS:000229160400004 (26) - scopus: 2-s2.0-19044400487 (27)
11573/138979 - 2005 -
Novel 1-[2-(Diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. A Structure-Activity Relationship Investigation. La Regina, Giuseppe; Ragno, Rino; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 4378-4388 - issn: 0022-2623 - wos: WOS:000230121800023 (43) - scopus: 2-s2.0-21244459659 (52)
11573/232310 - 2005 -
High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme Silvestri, Romano; Ragno, Rino; Artico, Marino; La Regina, Giuseppe - 01a Articolo in rivista
paper: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (American Society for Microbiology:PO Box 11127:Birmingham, AL 35201:(800)633-4931, (205)995-1567, EMAIL: asm.nonmembers.subs@ebsco.com, INTERNET: http://www.asm.org, Fax: (205)995-1588) pp. 4546-4554 - issn: 0066-4804 - wos: WOS:000233020900016 (18) - scopus: 2-s2.0-27644482321 (20)
11573/232365 - 2005 -
Design, Synthesis and Biological Evaluation of New Pyrrole MAO-B Inhibitors. La Regina, Giuseppe; Ragno, Rino; Agostinelli, Enzo; Turini, Paola; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
book: Abstracts - ()
11573/233895 - 2005 -
Arylthioindoles, Potent Inhibitors of Tubulin Polymerization. La Regina, Giuseppe; Coluccia, Antonio; Piscitelli, Francesco; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Second Joint Italian - Swiss Meeting on Medicinal Chemistry (Modena)
book: Abstracts - ()
11573/235905 - 2005 -
Dihalo Indolyl Aryl Sulfones (IASs) Highly Active In Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations. La Regina, Giuseppe; Ragno, Rino; Coluccia, Antonio; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: 20th International Congress of Heterocyclic Chemistry (Palermo)
book: Abstracts - ()
11573/240140 - 2005 -
Indolyl aryl Sulfones (IASs): Development of highly potent NNRTIs active against wt-HIV-1 and clinically relevant drug resistant mutants Silvestri, Romano; Artico, Marino - 01a Articolo in rivista
paper: CURRENT PHARMACEUTICAL DESIGN (Bentham Science Publishers BV:PO Box 7917, Exec Ste Y 26, Saif Zone Sharjah Uae:011 971 6 5571132, EMAIL: benthams@emirates.net.ae, INTERNET: http://www.bentham.org, Fax: 011 971 6 5571134) pp. 3779-3806 - issn: 1381-6128 - wos: WOS:000232839600006 (21) - scopus: 2-s2.0-27744462731 (20)
11573/359603 - 2005 -
Docking and 3-D QSAR Studies on Indolyl Aryl Sulfones. Binding Mode Exploration at the HIV-1 Reverse Transcriptase Non-Nucleoside Binding Site and Design of Highly Active N-(2-Hydroxyethyl)carboxamide and N-(2-Hydroxyethyl)carbohydrazide Derivatives. Ragno, Rino; Artico, Marino; La Regina, Giuseppe; Coluccia, Antonio; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 213-223 - issn: 0022-2623 - wos: WOS:000226212900021 (69) - scopus: 2-s2.0-12144279076 (82)
11573/502726 - 2005 -
Chiral resolution and binding study of 1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino[2,1-d]pyrrolo[1,2-b] [1,2,5]benzotriazepine (10-methyl-10-azaaptazepine) and 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo[1,2-b][1,2,5]-benzothiadiazepine 10,10-dioxide (tiaaptazepine). La Regina, Giuseppe; La Torre, Filippo; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 931-937 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-27744558834 (2)
11573/203455 - 2004 -
Studies of enantiomerization barrier of 1-[2-(2-methoxycarbonylacetamido) benzenesulfonyl]-1H-pyrrole by enantio selective dynamic HPLC. La Torre, Filippo; Silvestri, Romano; Di Pasquali, Alessandra - 04a Atto di comunicazione a congresso
conference: 25th International Symposium on Chromatograph (Parigi)
book: Book of Abstracts - ()
11573/233541 - 2004 -
Simple, Short Peptide Derivatives of L-737,126 Active In Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3892-3896 - issn: 0022-2623 - wos: WOS:000222530700019 (49) - scopus: 2-s2.0-3142651936 (52)
11573/238383 - 2004 -
Anti-HIV-1 Activity of Pyrryl Aryl Sulfone (PAS) Derivatives: Synthesis and SAR Studies of Novel Esters and Amides at the Position 2 of the Pyrrole Nucleus. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe - 01a Articolo in rivista
paper: IL FARMACO (Attuale:ELSEVIER SCIENCE SA, PO BOX 564, LAUSANNE, SWITZERLAND, 1001
Societa Chimica Italiana:Viale Liegi 48, 00198 Rome Italy:011 39 06 8549691, EMAIL: soc.chim.it@agora.stm.it, Fax: 011 39 06 8548734) pp. 201-210 - issn: 0014-827X - wos: (0) - scopus: 2-s2.0-1342321756 (39)
11573/239423 - 2004 -
Synthetic approaches to difluoroindolecarboxylic acid ethyl esters. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe - 01a Articolo in rivista
paper: ARKIVOC (ARKAT USA INC, C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, USA, FL, 32611) pp. 26-31 - issn: 1551-7012 - wos: WOS:000222493900003 (5) - scopus: 2-s2.0-2942631454 (6)
11573/360936 - 2004 -
Arylthioindoles, potent inhibitors of tubulin polymerization. La Regina, Giuseppe; Coluccia, Antonio; Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 6120-6123 - issn: 0022-2623 - wos: WOS:000225409400003 (253) - scopus: 2-s2.0-10044236627 (262)
11573/396498 - 2004 -
Chemotherapeutic Agents for the Treatment of Fungal Infections. Imidazole Derivatives HighlyActive Against Candida albicans. La Regina, Giuseppe; Nencioni, Lucia; Palamara, Anna Teresa; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()
11573/396687 - 2004 -
Studies on Novel Agents for Depression and Parkinson’s Disease. Potent Pyrrole and Indole Monoamine Oxidase Inhibitors. La Regina, Giuseppe; Ragno, Rino; Agostinelli, Enzo; Turini, Paola; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()
11573/396688 - 2004 -
New Agents Highly Active in Cancer Therapy. Indoles, Potent Inhibitors of Tubulin Polymerization. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Conferenza sulla Ricerca Scientifica Facoltà di Farmacia - Dalle molecole agli organismi (Roma)
book: Riassunti - ()
11573/396698 - 2004 -
Arylthioindoles, Potent Inhibitors of Tubulin Polymerization. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Istituto Pasteur – Fondazione Cenci Bolognetti, Giornate Scientifiche Della Fondazione, Molecular Recognition (Roma)
book: Abstracts - ()
11573/396700 - 2004 -
Novel Indolyl Aryl Sulfones (IAAs) Highly Active in Vitro Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Cost D28 MC Action. Natural Products as a Source for Discovery, Synthesis, and Application of New Pharmaceuticals. (Siena)
book: Program & Abstracts - ()
11573/396702 - 2004 -
Imidazole Derivatives Highly Active Against Candida Albicans. La Regina, Giuseppe; Nencioni, Lucia; Palamara, Anna Teresa; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: Cost D28 MC Action. Natural Products as a Source for Discovery, Synthesis, and Application of New Pharmaceuticals. (Siena)
book: Program & Abstracts - ()
11573/396712 - 2004 -
Nuovi Indolil Aril Solfoni 2-Sostituiti Attivi su HIV-1 WT e su Altri Mutanti Resistenti. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()
11573/396722 - 2004 -
Potenti Inibitori della Tubulina a Struttura Indolica. La Regina, Giuseppe; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()
11573/396727 - 2004 -
Derivati Imidazolici Isomeri dell’Econazolo ad Azione Anti-Candida. La Regina, Giuseppe; Nencioni, Lucia; Palamara, Anna Teresa; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()
11573/396732 - 2004 -
Potenti Inibitori delle Monoamino Ossidasi a Struttura Pirrolica ed Indolica. La Regina, Giuseppe; Ragno, Rino; Agostinelli, Enzo; Turini, Paola; Artico, Marino; Silvestri, Romano - 04a Atto di comunicazione a congresso
conference: XVII Convegno Nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana (Pisa)
book: Atti del Convegno - ()
11573/502712 - 2004 -
Imidazole Analogues of Fluoxetine, a Novel Class of Anti-Candida Agents. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; D'auria, Felicia Diodata; Nencioni, Lucia; Palamara, Anna Teresa - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 3924-3926 - issn: 0022-2623 - wos: WOS:000222856800004 (50) - scopus: 2-s2.0-3242778536 (53)
11573/189709 - 2003 -
Analoghi azolici della fluoxetina, una nuova classe di agenti antifungini D'auria, Felicia Diodata; Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Palamara, Anna Teresa - 04a Atto di comunicazione a congresso
conference: 31° Congresso Nazionale Società Italiana di Microbiologia (Roma)
book: Riassunti - ()
11573/218643 - 2003 -
N-Benzyl and N-propargyl 1H-pyrrole-2-carboxyamides, as simple and effective monoamine oxidase inhibitors. Silvestri, Romano; Artico, Marino; Befani, Olivia; Turini, Paola; Agostinelli, Enzo - 13a Altro ministeriale
11573/249931 - 2003 -
Novel Indolyl Aryl Sulfones Active against HIV-1 Carrying NNRTI Resistance Mutations: Synthesis and SAR Studies. Silvestri, Romano; La Regina, Giuseppe; Artico, Marino - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 2482-2493 - issn: 0022-2623 - wos: WOS:000183220400024 (153) - scopus: 2-s2.0-12444315080 (162)
11573/255841 - 2003 -
Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B Silvestri, Romano; La Regina, Giuseppe; Agostinelli, Enzo; Turini, Paola - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 917-920 - issn: 0022-2623 - wos: WOS:000181399100004 (41) - scopus: 2-s2.0-0037435063 (41)
11573/396740 - 2003 -
Docking and 3-D QSAR Studies on Indolyl Aryl Solfones (IASs). Binding Mode Exploration at the HIV-1 RT NNBS and Structure Based Drug Design. Ragno, Rino; Silvestri, Romano; La Regina, Giuseppe; Artico, Marino - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()
11573/396772 - 2003 -
Azole Analogues of Fluoxetine, a Novel Class of anti-Candida Agents. Silvestri, Romano; La Regina, Giuseppe; Artico, Marino; D'auria, Felicia Diodata - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()
11573/396947 - 2003 -
Synthesis of Indole Derivatives active against Flaviviridae Viruses. Silvestri, Romano; La Regina, Giuseppe; Artico, Marino - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()
11573/57586 - 2003 -
Pyrrolo[1,2-b]benzothiadiazepines (PBTDs) induce Apoptosis in Chronic Myelogenous K562 Leucemic Cells Silvestri, Romano; La Regina, Giuseppe; Artico, Marino - 04a Atto di comunicazione a congresso
conference: XXI Congresso Nazionale della Società Chimica Italiana (Torino)
book: Atti - ()
11573/252766 - 2002 -
Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase Silvestri, Romano; Artico, Marino; Ragno, Rino - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1567-1576 - issn: 0022-2623 - wos: WOS:000174844600004 (65) - scopus: 2-s2.0-0037061639 (62)
11573/253535 - 2002 -
Anti-HIV-1 NNRT Agents: Acylamino Pyrryl Aryl Sulfones (APASs) as Truncated Analogues of Tricyclic PBTDs. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Ragno, Rino - 01a Articolo in rivista
paper: MEDICINAL CHEMISTRY RESEARCH (Birkhauser Boston Incorporated:c/o Springer Verlag, PO Box 2485:Secaucus, NJ 07096:(800)777-4643, (973)348-4033, Fax: (973)348-4505) pp. 195-218 - issn: 1054-2523 - wos: WOS:000178074100001 (8) - scopus: 2-s2.0-0036439429 (9)
11573/396783 - 2002 -
Agenti anti-HIV-1: Acilamino Pirril Aril Solfoni (APAS), Analoghi Troncati delle PBTD Tricicliche. Silvestri, Romano; La Regina, Giuseppe; Artico, Marino; Ragno, Rino - 04a Atto di comunicazione a congresso
conference: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica (Sorrento)
book: Atti del Convegno - ()
11573/396787 - 2002 -
N-Benzil e N-Propargil 1H-Pirrolo-2-carbossiamidi, Semplici ed Efficaci Inibitori delle Monoamino Ossidasi. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Agostinelli, Enzo; Turini, Paola - 04a Atto di comunicazione a congresso
conference: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica (Sorrento)
book: Atti del Convegno - ()
11573/396788 - 2002 -
N-Benzyl and N-Propargyl 1H-Pyrrole-2-carboxyamides, as Simple and Potent MAO Inhibitors. Silvestri, Romano; Artico, Marino; La Regina, Giuseppe; Agostinelli, Enzo; Turini, Paola - 04a Atto di comunicazione a congresso
conference: 23rd IUPAC – 2002. International Symposium on the Chemistry of Natural Products (Firenze)
book: Abstracts Book - ()
11573/396801 - 2002 -
Anti-HIV-1 NNRT Agents: Acylamino Pyrryl Aryl Sulfones (APASs) as Truncated Analogues of Tricyclic PBTDs. Silvestri, Romano; La Regina, Giuseppe; Artico, Marino; Ragno, Rino - 04a Atto di comunicazione a congresso
conference: 23rd IUPAC – 2002. International Symposium on the Chemistry of Natural Products (Firenze)
book: Abstracts Book - ()
11573/53418 - 2002 -
Attività anti-HIV-1 di Ariltiazolilcarbossiamidi, Nuova Classe di NNRTI ibridi tra PETT, UC781 e TDA Silvestri, Romano; Artico, Marino; Ragno, Rino - 04a Atto di comunicazione a congresso
book: XVI Convegno Nazionale della Divisione di Chimica Farmaceutica della SCI - ()
11573/72141 - 2002 -
A simplified synthesis of ethyl 5-chloro-6-fluro-1H-indole-2-carboxylate and ethyl 5-chloro-4-fluro-1H-indole-2-carboxylate Silvestri, Romano - 01a Articolo in rivista
paper: ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (Organic Preparations and Procedures Incorporated:PO Box 610009:Newton Highlands, MA 02161:(617)287-6130, EMAIL: jp.anselme@umb.edu, Fax: (617)287-6030) pp. 507-510 - issn: 0030-4948 - wos: (0) - scopus: 2-s2.0-0036796527 (7)
11573/256233 - 2000 -
Structure based design, synthesis and biological evaluation of novel pyrrolyl aryl sulfones (PASs) active at nanomolar concentration as HIV-1 non nucleoside reverse transcriptase inhibitors. Artico, Marino; Silvestri, Romano - 01a Articolo in rivista
paper: JOURNAL OF MEDICINAL CHEMISTRY (Washington, DC: American Chemical Society) pp. 1886-1891 - issn: 0022-2623 - wos: WOS:000086969400025 (120) - scopus: 2-s2.0-0034075488 (122)
11573/453053 - 1992 -
AROMATIC HYDRAZIDES AS SPECIFIC INHIBITORS OF BOVINE SERUM AMINE OXIDASE Artico, Marino; Silvestri, Romano; Agostinelli, Enzo - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 219-228 - issn: 0223-5234 - wos: WOS:A1992HX47900005 (28) - scopus: 2-s2.0-0026716029 (28)
11573/470114 - 1992 -
Antibacterial and antifungal agents. XV. Synthesis and antifungal activity of structural analogues of bifonazole and ketoconazole. Artico, Marco; Ortar, Giorgio; Silvestri, Romano; Simonetti, Giovanna; Artico, Marino - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 687-694 - issn: 0365-6233 - wos: WOS:A1992JZ63600001 (5) - scopus: 2-s2.0-0026948071 (4)
11573/470167 - 1992 -
Researches on antibacterial and antifungal agents, XIV: Thiophene analogues of bifonazole Silvestri, Romano; Artico, Marco; Simonetti, Giovanna - 01a Articolo in rivista
paper: ARCHIV DER PHARMAZIE (Wiley-VCH Verlag GmBH:PO Box 101161, D 69451 Weinheim Germany:011 49 6201 606147, EMAIL: service@wiley-vch.de, INTERNET: http://www.wiley-vch.de, Fax: 011 49 6201 606328) pp. 199-204 - issn: 0365-6233 - wos: WOS:A1992HR85900002 (12) - scopus: 2-s2.0-0026563544 (12)
11573/470215 - 1992 -
Research on antibacterial and antifungal agents. 16. Synthesis and antifungal activities of 1-[α-(1-naphthyl)benzyl]imidazole derivatives and related 2-naphthyl isomers Artico, Marino; Silvestri, Romano; Artico, Marco - 01a Articolo in rivista
paper: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (Editions Scientifique & Medical Elsevier:23 Rue Linois, F 75724 Paris Cedex 15 France:011 33 1 71724646, INTERNET: http://www.elsevier.fr, Fax: 011 33 1 71724664) pp. 693-699 - issn: 0223-5234 - wos: WOS:A1992JZ82500006 (17) - scopus: 2-s2.0-0026458733 (17)
11573/70421 - 1992 -
Bovine Serum Amine Oxidase: Half-Site Reactivity with Phenylhydrazine, Semicarbazide and Aromatic Hydrazides. Agostinelli, Enzo; Silvestri, Romano; Artico, Marino - 01a Articolo in rivista
paper: BIOCHEMISTRY (American Chemical Society:1155 Sixteenth Street Northwest:Washington, DC 20036:(800)227-5558, EMAIL: service@acs.org, INTERNET: http://www.pubs.acs.org, Fax: (614)447-3671) pp. 2615-2621 - issn: 0006-2960 - wos: WOS:A1992HH48900023 (59) - scopus: 2-s2.0-0026562320 (59)